Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              20     390
NP_001035957                                                           20     390
XP_005276506                                                           20     390
XP_006721991                                                           20     390
XP_006721990                                                           20     390
XP_006721989                                                           20     390
XP_005258041                                                           20     390
XP_006721988                                                           20     390
XP_006721987                                                           20     390
XP_006721986                                                           20     390
XP_005258040                                                           20     390
XP_006721985                                                           20     390
XP_006720412                                                           20     390
NP_005094                                                              17    3301
XP_005271792                                                           17    3301
XP_005271791                                                           17    3301
NP_001182156                                                           16    5631
NP_060106                                                              16    5631
XP_005259075                                                           16    5631
XP_005259074                                                           16    5631
XP_006723312                                                           16    5631
NP_665873                                                              16    7355
NP_009215                                                              16    7355
NP_059108                                                              16    7355
NP_001009555                                                           16    7355
NP_001122396                                                           16    7355
NP_001230278                                                           16    7355
XP_006714165                                                           16    7355
XP_005262824                                                           16    7355
XP_006714164                                                           16    7355
XP_006714163                                                           16    7355
XP_006714162                                                           16    7355
XP_006714161                                                           16    7355
XP_006714160                                                           16    7355
XP_005262823                                                           16    7355
NP_001122395                                                           16    7355
NP_870991                                                              15    9605
NP_060783                                                              15    9605
NP_001193923                                                           15    9605
NP_001193924                                                           15    9605
NP_001364                                                              15    9605
NP_001193925                                                           15    9605
NP_694999                                                              15    9605
NP_065978                                                              15    9605
XP_005270269                                                           15    9605
XP_005248036                                                           15    9605
XP_005248035                                                           15    9605
XP_005248034                                                           15    9605
XP_006713297                                                           15    9605
XP_006713296                                                           15    9605
XP_006713295                                                           15    9605
XP_005265345                                                           15    9605
XP_006713294                                                           15    9605
XP_006713293                                                           15    9605
XP_006713292                                                           15    9605
XP_006713291                                                           15    9605
XP_006713290                                                           15    9605
XP_006713289                                                           15    9605
XP_005265340                                                           15    9605
XP_005265339                                                           15    9605
XP_006713288                                                           15    9605
XP_005265337                                                           15    9605
XP_005265336                                                           15    9605
XP_006713287                                                           15    9605
XP_006713286                                                           15    9605
XP_005265332                                                           15    9605
XP_006713285                                                           15    9605
XP_006713284                                                           15    9605
XP_006713283                                                           15    9605
XP_006711798                                                           15    9605
NP_001135780                                                           15    9605
>NP_000258
          Length = 2818

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ARRDDLSF 8
            ARRDDLSF
Sbjct: 1024 ARRDDLSF 1031
>NP_001035957
          Length = 2839

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ARRDDLSF 8
            ARRDDLSF
Sbjct: 1024 ARRDDLSF 1031
>XP_005276506
          Length = 151

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  ARRDDLSF 8
          ARRDDLSF
Sbjct: 57 ARRDDLSF 64
>XP_006721991
          Length = 1632

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ARRDDLSF 8
            ARRDDLSF
Sbjct: 1034 ARRDDLSF 1041
>XP_006721990
          Length = 2823

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ARRDDLSF 8
            ARRDDLSF
Sbjct: 1034 ARRDDLSF 1041
>XP_006721989
          Length = 2823

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ARRDDLSF 8
            ARRDDLSF
Sbjct: 1034 ARRDDLSF 1041
>XP_005258041
          Length = 2836

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ARRDDLSF 8
            ARRDDLSF
Sbjct: 1024 ARRDDLSF 1031
>XP_006721988
          Length = 2846

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ARRDDLSF 8
            ARRDDLSF
Sbjct: 1034 ARRDDLSF 1041
>XP_006721987
          Length = 2849

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ARRDDLSF 8
            ARRDDLSF
Sbjct: 1034 ARRDDLSF 1041
>XP_006721986
          Length = 2854

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ARRDDLSF 8
            ARRDDLSF
Sbjct: 1021 ARRDDLSF 1028
>XP_005258040
          Length = 2857

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ARRDDLSF 8
            ARRDDLSF
Sbjct: 1024 ARRDDLSF 1031
>XP_006721985
          Length = 2867

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1    ARRDDLSF 8
            ARRDDLSF
Sbjct: 1034 ARRDDLSF 1041
>XP_006720412
          Length = 128

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1  ARRDDLSF 8
          ARRDDLSF
Sbjct: 34 ARRDDLSF 41
>NP_005094
          Length = 392

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARRDDLSF 8
           ARRD+L F
Sbjct: 255 ARRDELEF 262
>XP_005271792
          Length = 392

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARRDDLSF 8
           ARRD+L F
Sbjct: 255 ARRDELEF 262
>XP_005271791
          Length = 392

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARRDDLSF 8
           ARRD+L F
Sbjct: 255 ARRDELEF 262
>NP_001182156
          Length = 1069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARRDDLSF 8
           ARR DL+F
Sbjct: 610 ARRKDLAF 617
>NP_060106
          Length = 1214

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARRDDLSF 8
           ARR DL+F
Sbjct: 610 ARRKDLAF 617
>XP_005259075
          Length = 678

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ARRDDLSF 8
          ARR DL+F
Sbjct: 74 ARRKDLAF 81
>XP_005259074
          Length = 785

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARRDDLSF 8
           ARR DL+F
Sbjct: 181 ARRKDLAF 188
>XP_006723312
          Length = 1129

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARRDDLSF 8
           ARR DL+F
Sbjct: 525 ARRKDLAF 532
>NP_665873
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RRDDLSFS 9
           RR++LSF+
Sbjct: 195 RREELSFA 202
>NP_009215
          Length = 349

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   RDDLSFS 9
           +DDLSF+
Sbjct: 126 KDDLSFA 132
>NP_059108
          Length = 666

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RRDDLSFS 9
           RR++LSF+
Sbjct: 195 RREELSFA 202
>NP_001009555
          Length = 790

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RRDDLSFS 9
           ++D+LSFS
Sbjct: 586 QKDELSFS 593
>NP_001122396
          Length = 731

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RRDDLSFS 9
           ++D+LSFS
Sbjct: 527 QKDELSFS 534
>NP_001230278
          Length = 767

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RRDDLSFS 9
           ++D+LSFS
Sbjct: 563 QKDELSFS 570
>XP_006714165
          Length = 790

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RRDDLSFS 9
           ++D+LSFS
Sbjct: 586 QKDELSFS 593
>XP_005262824
          Length = 790

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RRDDLSFS 9
           ++D+LSFS
Sbjct: 586 QKDELSFS 593
>XP_006714164
          Length = 1011

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RRDDLSFS 9
           ++D+LSFS
Sbjct: 807 QKDELSFS 814
>XP_006714163
          Length = 1011

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RRDDLSFS 9
           ++D+LSFS
Sbjct: 807 QKDELSFS 814
>XP_006714162
          Length = 1011

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RRDDLSFS 9
           ++D+LSFS
Sbjct: 807 QKDELSFS 814
>XP_006714161
          Length = 1020

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RRDDLSFS 9
           ++D+LSFS
Sbjct: 816 QKDELSFS 823
>XP_006714160
          Length = 1047

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RRDDLSFS 9
           ++D+LSFS
Sbjct: 843 QKDELSFS 850
>XP_005262823
          Length = 1070

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RRDDLSFS 9
           ++D+LSFS
Sbjct: 866 QKDELSFS 873
>NP_001122395
          Length = 767

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   RRDDLSFS 9
           ++D+LSFS
Sbjct: 563 QKDELSFS 570
>NP_870991
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RRDDLS 7
           RRDD+S
Sbjct: 400 RRDDIS 405
>NP_060783
          Length = 1582

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 488 ARRDDI 493
>NP_001193923
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RRDDLS 7
           RRDD+S
Sbjct: 393 RRDDIS 398
>NP_001193924
          Length = 440

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RRDDLS 7
           RRDD+S
Sbjct: 393 RRDDIS 398
>NP_001364
          Length = 4515

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    RDDLSFS 9
            +DD SFS
Sbjct: 4070 KDDFSFS 4076
>NP_001193925
          Length = 430

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RRDDLS 7
           RRDD+S
Sbjct: 383 RRDDIS 388
>NP_694999
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DDLSFS 9
           DD+SFS
Sbjct: 318 DDISFS 323
>NP_065978
          Length = 419

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DDLSFS 9
           DD+SFS
Sbjct: 151 DDMSFS 156
>XP_005270269
          Length = 226

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ARRDDLSFS 9
          A+R DLSF+
Sbjct: 33 AKRLDLSFN 41
>XP_005248036
          Length = 230

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RRDDLS 7
           RRDD+S
Sbjct: 183 RRDDIS 188
>XP_005248035
          Length = 342

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RRDDLS 7
           RRDD+S
Sbjct: 295 RRDDIS 300
>XP_005248034
          Length = 447

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 2   RRDDLS 7
           RRDD+S
Sbjct: 400 RRDDIS 405
>XP_006713297
          Length = 1600

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 506 ARRDDI 511
>XP_006713296
          Length = 1615

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 506 ARRDDI 511
>XP_006713295
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 474 ARRDDI 479
>XP_005265345
          Length = 1627

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 506 ARRDDI 511
>XP_006713294
          Length = 1652

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 506 ARRDDI 511
>XP_006713293
          Length = 1667

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 506 ARRDDI 511
>XP_006713292
          Length = 1670

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 506 ARRDDI 511
>XP_006713291
          Length = 1682

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 506 ARRDDI 511
>XP_006713290
          Length = 1690

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 474 ARRDDI 479
>XP_006713289
          Length = 1697

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 506 ARRDDI 511
>XP_005265340
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 488 ARRDDI 493
>XP_005265339
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 488 ARRDDI 493
>XP_006713288
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 488 ARRDDI 493
>XP_005265337
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 488 ARRDDI 493
>XP_005265336
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 488 ARRDDI 493
>XP_006713287
          Length = 1704

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 488 ARRDDI 493
>XP_006713286
          Length = 1707

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 506 ARRDDI 511
>XP_005265332
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 506 ARRDDI 511
>XP_006713285
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 506 ARRDDI 511
>XP_006713284
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 506 ARRDDI 511
>XP_006713283
          Length = 1722

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARRDDL 6
           ARRDD+
Sbjct: 506 ARRDDI 511
>XP_006711798
          Length = 4586

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    RDDLSFS 9
            +DD SFS
Sbjct: 4132 KDDFSFS 4138
>NP_001135780
          Length = 2156

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   DDLSFS 9
           DD+SFS
Sbjct: 219 DDISFS 224
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.134    0.362 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 563,136
Number of extensions: 1037
Number of successful extensions: 71
Number of sequences better than 10000.0: 71
Number of HSP's gapped: 71
Number of HSP's successfully gapped: 71
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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