Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_542779                                                              17    2528
NP_001161074                                                           17    2528
NP_001161071                                                           17    2528
NP_001161073                                                           17    2528
NP_001161072                                                           17    2528
XP_005249232                                                           17    2528
NP_000273                                                              17    4312
NP_001171475                                                           17    4312
NP_001185863                                                           17    4312
NP_258261                                                              17    4312
NP_665879                                                              17    4312
XP_005254116                                                           17    4312
XP_005249527                                                           17    4312
XP_006715303                                                           17    4312
NP_078853                                                              16    5631
NP_001267717                                                           16    5631
NP_149351                                                              16    5631
NP_001267721                                                           16    5631
NP_061859                                                              16    5631
NP_001267718                                                           16    5631
XP_006717320                                                           16    5631
XP_006713954                                                           16    5631
XP_006713953                                                           16    5631
XP_006713952                                                           16    5631
XP_005248031                                                           16    5631
XP_006713951                                                           16    5631
NP_006647                                                              16    5631
NP_065076                                                              16    7355
NP_653327                                                              16    7355
NP_001186312                                                           16    7355
NP_001186311                                                           16    7355
NP_001186310                                                           16    7355
NP_001186309                                                           16    7355
XP_006723662                                                           16    7355
XP_005260825                                                           16    7355
XP_006723661                                                           16    7355
XP_005265883                                                           16    7355
NP_060426                                                              16    7355
NP_000352                                                              15    9605
NP_005148                                                              15    9605
NP_009297                                                              15    9605
NP_001012745                                                           15    9605
NP_006403                                                              15    9605
NP_060587                                                              15    9605
NP_001120650                                                           15    9605
NP_001275980                                                           15    9605
NP_060203                                                              15    9605
NP_848652                                                              15    9605
NP_055646                                                              15    9605
NP_001275982                                                           15    9605
NP_001275981                                                           15    9605
NP_150377                                                              15    9605
XP_006721650                                                           15    9605
XP_005270021                                                           15    9605
XP_005270020                                                           15    9605
XP_005270019                                                           15    9605
XP_005266060                                                           15    9605
XP_005272346                                                           15    9605
XP_005272345                                                           15    9605
XP_005272344                                                           15    9605
XP_006713955                                                           15    9605
XP_005272341                                                           15    9605
XP_005272340                                                           15    9605
XP_006713495                                                           15    9605
NP_795370                                                              15    9605
NP_076407                                                              15    9605
NP_003546                                                              15    9605
>NP_542779
          Length = 496

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           ARLC + SR
Sbjct: 134 ARLCCVASR 142
>NP_001161074
          Length = 484

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           ARLC + SR
Sbjct: 122 ARLCCVASR 130
>NP_001161071
          Length = 497

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           ARLC + SR
Sbjct: 135 ARLCCVASR 143
>NP_001161073
          Length = 484

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           ARLC + SR
Sbjct: 122 ARLCCVASR 130
>NP_001161072
          Length = 484

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           ARLC + SR
Sbjct: 122 ARLCCVASR 130
>XP_005249232
          Length = 189

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   ARLCLIVS 8
           ARLCL VS
Sbjct: 95  ARLCLAVS 102
>NP_000273
          Length = 728

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ARLCLIVSR 9
          +R CL+VSR
Sbjct: 41 SRQCLMVSR 49
>NP_001171475
          Length = 681

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ARLCLIVSR 9
          +R CL+VSR
Sbjct: 41 SRQCLMVSR 49
>NP_001185863
          Length = 1492

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ARLCLIV 7
           ARLCL++
Sbjct: 170 ARLCLLI 176
>NP_258261
          Length = 1464

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ARLCLIV 7
           ARLCL++
Sbjct: 127 ARLCLLI 133
>NP_665879
          Length = 349

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RLCLIVSR 9
           RLC +VSR
Sbjct: 328 RLCPVVSR 335
>XP_005254116
          Length = 640

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  ARLCLIVSR 9
          +R CL+VSR
Sbjct: 41 SRQCLMVSR 49
>XP_005249527
          Length = 822

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ARLCLIV 7
           ARLCL++
Sbjct: 170 ARLCLLI 176
>XP_006715303
          Length = 1463

 Score = 16.5 bits (31), Expect =  4312
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   ARLCLIV 7
           ARLCL++
Sbjct: 170 ARLCLLI 176
>NP_078853
          Length = 1288

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           ARLC ++ R
Sbjct: 528 ARLCFLLGR 536
>NP_001267717
          Length = 254

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  ARLCLI 6
          ARLCLI
Sbjct: 14 ARLCLI 19
>NP_149351
          Length = 269

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  ARLCLI 6
          ARLCLI
Sbjct: 29 ARLCLI 34
>NP_001267721
          Length = 128

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  ARLCLI 6
          ARLCLI
Sbjct: 29 ARLCLI 34
>NP_061859
          Length = 1336

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           ARLC ++ R
Sbjct: 560 ARLCFLLGR 568
>NP_001267718
          Length = 159

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  ARLCLI 6
          ARLCLI
Sbjct: 29 ARLCLI 34
>XP_006717320
          Length = 301

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1  ARLCLI 6
          ARLCLI
Sbjct: 61 ARLCLI 66
>XP_006713954
          Length = 1043

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           ARLC ++ R
Sbjct: 267 ARLCFLLGR 275
>XP_006713953
          Length = 1043

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           ARLC ++ R
Sbjct: 267 ARLCFLLGR 275
>XP_006713952
          Length = 1165

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           ARLC ++ R
Sbjct: 389 ARLCFLLGR 397
>XP_005248031
          Length = 1260

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           ARLC ++ R
Sbjct: 484 ARLCFLLGR 492
>XP_006713951
          Length = 1309

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           ARLC ++ R
Sbjct: 533 ARLCFLLGR 541
>NP_006647
          Length = 461

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           ARLC I S+
Sbjct: 157 ARLCFIYSQ 165
>NP_065076
          Length = 1873

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           A LC+ +SR
Sbjct: 609 ANLCVYISR 617
>NP_653327
          Length = 691

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARLCLI 6
           ARLCL+
Sbjct: 186 ARLCLV 191
>NP_001186312
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARLCLI 6
           ARLCL+
Sbjct: 158 ARLCLV 163
>NP_001186311
          Length = 677

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARLCLI 6
           ARLCL+
Sbjct: 172 ARLCLV 177
>NP_001186310
          Length = 680

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARLCLI 6
           ARLCL+
Sbjct: 175 ARLCLV 180
>NP_001186309
          Length = 693

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARLCLI 6
           ARLCL+
Sbjct: 188 ARLCLV 193
>XP_006723662
          Length = 1920

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           A LC+ +SR
Sbjct: 609 ANLCVYISR 617
>XP_005260825
          Length = 1923

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           A LC+ +SR
Sbjct: 609 ANLCVYISR 617
>XP_006723661
          Length = 1970

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ARLCLIVSR 9
           A LC+ +SR
Sbjct: 609 ANLCVYISR 617
>XP_005265883
          Length = 679

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ARLCLI 6
           ARLCL+
Sbjct: 174 ARLCLV 179
>NP_060426
          Length = 448

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   RLCLIVSR 9
           +LCL VSR
Sbjct: 106 KLCLEVSR 113
>NP_000352
          Length = 575

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ARLCLIVS 8
           A LCL+V+
Sbjct: 524 ASLCLVVA 531
>NP_005148
          Length = 1130

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    LCLIVSR 9
            LCL +SR
Sbjct: 1039 LCLAISR 1045
>NP_009297
          Length = 1149

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3    LCLIVSR 9
            LCL +SR
Sbjct: 1058 LCLAISR 1064
>NP_001012745
          Length = 246

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ARLCLIVS 8
          AR C+IVS
Sbjct: 89 ARPCVIVS 96
>NP_006403
          Length = 278

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  ARLCLIVS 8
          AR C+IVS
Sbjct: 89 ARPCVIVS 96
>NP_060587
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   CLIVSR 9
           CL+VSR
Sbjct: 913 CLLVSR 918
>NP_001120650
          Length = 983

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARLCLIVS 8
           A LC+IVS
Sbjct: 517 ALLCVIVS 524
>NP_001275980
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARLCLIVS 8
           A LC+IVS
Sbjct: 428 ALLCVIVS 435
>NP_060203
          Length = 975

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARLCLIVS 8
           A LC+IVS
Sbjct: 509 ALLCVIVS 516
>NP_848652
          Length = 302

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   ARLCLIVSR 9
           A LC  VSR
Sbjct: 125 AALCFAVSR 133
>NP_055646
          Length = 2925

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RLCLIVS 8
            R CL+VS
Sbjct: 2681 RACLVVS 2687
>NP_001275982
          Length = 480

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARLCLIVS 8
           A LC+IVS
Sbjct: 428 ALLCVIVS 435
>NP_001275981
          Length = 850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARLCLIVS 8
           A LC+IVS
Sbjct: 384 ALLCVIVS 391
>NP_150377
          Length = 918

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  ARLCLI 6
          ARLCL+
Sbjct: 8  ARLCLL 13
>XP_006721650
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LCLIVS 8
           LCLI+S
Sbjct: 212 LCLIIS 217
>XP_005270021
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   CLIVSR 9
           CL+VSR
Sbjct: 442 CLLVSR 447
>XP_005270020
          Length = 965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   CLIVSR 9
           CL+VSR
Sbjct: 654 CLLVSR 659
>XP_005270019
          Length = 965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   CLIVSR 9
           CL+VSR
Sbjct: 654 CLLVSR 659
>XP_005266060
          Length = 955

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  ARLCLI 6
          ARLCL+
Sbjct: 8  ARLCLL 13
>XP_005272346
          Length = 539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARLCLIVS 8
           A LC+IVS
Sbjct: 517 ALLCVIVS 524
>XP_005272345
          Length = 619

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARLCLIVS 8
           A LC+IVS
Sbjct: 517 ALLCVIVS 524
>XP_005272344
          Length = 624

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARLCLIVS 8
           A LC+IVS
Sbjct: 517 ALLCVIVS 524
>XP_006713955
          Length = 861

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARLCLIVS 8
           A LC+IVS
Sbjct: 395 ALLCVIVS 402
>XP_005272341
          Length = 894

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARLCLIVS 8
           A LC+IVS
Sbjct: 428 ALLCVIVS 435
>XP_005272340
          Length = 913

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   ARLCLIVS 8
           A LC+IVS
Sbjct: 447 ALLCVIVS 454
>XP_006713495
          Length = 2969

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2    RLCLIVS 8
            R CL+VS
Sbjct: 2725 RACLVVS 2731
>NP_795370
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LCLIVS 8
           LCLI+S
Sbjct: 243 LCLIIS 248
>NP_076407
          Length = 309

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1  ARLCLI 6
          AR+CLI
Sbjct: 54 ARICLI 59
>NP_003546
          Length = 313

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   LCLIVS 8
           LCLI+S
Sbjct: 212 LCLIIS 217
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.349    0.148    0.451 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 502,949
Number of extensions: 504
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.8 bits)
S2: 28 (15.4 bits)

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