Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000258                                                              18    1135
NP_001035957                                                           18    1135
XP_006721991                                                           18    1135
XP_006721990                                                           18    1135
XP_006721989                                                           18    1135
XP_005258041                                                           18    1135
XP_006721988                                                           18    1135
XP_006721987                                                           18    1135
XP_006721986                                                           18    1135
XP_005258040                                                           18    1135
XP_006721985                                                           18    1135
NP_001230694                                                           16    5631
NP_036329                                                              16    5631
NP_001230693                                                           16    5631
NP_569118                                                              16    5631
NP_932065                                                              16    5631
NP_932064                                                              16    5631
XP_006720650                                                           16    5631
XP_005254559                                                           16    5631
XP_006720649                                                           16    5631
XP_005254557                                                           16    5631
XP_006717095                                                           16    5631
XP_006717094                                                           16    5631
XP_005251923                                                           16    5631
XP_005245738                                                           16    5631
XP_006711755                                                           16    5631
XP_005245737                                                           16    5631
NP_001135389                                                           16    5631
NP_060213                                                              16    5631
NP_005742                                                              16    7355
NP_671714                                                              16    7355
NP_004437                                                              16    7355
XP_006715890                                                           16    7355
XP_005250160                                                           16    7355
XP_005250159                                                           16    7355
NP_001239553                                                           15    9605
NP_066267                                                              15    9605
NP_001106272                                                           15    9605
NP_001106271                                                           15    9605
NP_066920                                                              15    9605
XP_006717852                                                           15    9605
XP_006717851                                                           15    9605
XP_006717850                                                           15    9605
XP_006717849                                                           15    9605
XP_006717848                                                           15    9605
XP_006717847                                                           15    9605
XP_006717846                                                           15    9605
XP_006717845                                                           15    9605
XP_005264571                                                           15    9605
XP_005264570                                                           15    9605
XP_006712148                                                           15    9605
XP_006712147                                                           15    9605
XP_006712146                                                           15    9605
XP_006712145                                                           15    9605
XP_006712144                                                           15    9605
XP_006712143                                                           15    9605
XP_005264569                                                           15    9605
NP_001106273                                                           15    9605
>NP_000258
          Length = 2818

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQTKLEVVL 9
           AQTKLEV L
Sbjct: 683 AQTKLEVAL 691
>NP_001035957
          Length = 2839

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQTKLEVVL 9
           AQTKLEV L
Sbjct: 683 AQTKLEVAL 691
>XP_006721991
          Length = 1632

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQTKLEVVL 9
           AQTKLEV L
Sbjct: 693 AQTKLEVAL 701
>XP_006721990
          Length = 2823

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQTKLEVVL 9
           AQTKLEV L
Sbjct: 693 AQTKLEVAL 701
>XP_006721989
          Length = 2823

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQTKLEVVL 9
           AQTKLEV L
Sbjct: 693 AQTKLEVAL 701
>XP_005258041
          Length = 2836

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQTKLEVVL 9
           AQTKLEV L
Sbjct: 683 AQTKLEVAL 691
>XP_006721988
          Length = 2846

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQTKLEVVL 9
           AQTKLEV L
Sbjct: 693 AQTKLEVAL 701
>XP_006721987
          Length = 2849

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQTKLEVVL 9
           AQTKLEV L
Sbjct: 693 AQTKLEVAL 701
>XP_006721986
          Length = 2854

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQTKLEVVL 9
           AQTKLEV L
Sbjct: 680 AQTKLEVAL 688
>XP_005258040
          Length = 2857

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQTKLEVVL 9
           AQTKLEV L
Sbjct: 683 AQTKLEVAL 691
>XP_006721985
          Length = 2867

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AQTKLEVVL 9
           AQTKLEV L
Sbjct: 693 AQTKLEVAL 701
>NP_001230694
          Length = 370

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AQTKLEVV 8
           AQTKL++V
Sbjct: 306 AQTKLQLV 313
>NP_036329
          Length = 1069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQTKLEVV 8
            AQTKL++V
Sbjct: 1015 AQTKLQLV 1022
>NP_001230693
          Length = 253

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AQTKLEVV 8
           AQTKL++V
Sbjct: 189 AQTKLQLV 196
>NP_569118
          Length = 882

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AQTKLEVVL 9
           +QT+L++VL
Sbjct: 382 SQTRLQIVL 390
>NP_932065
          Length = 847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AQTKLEVVL 9
           +QT+L++VL
Sbjct: 398 SQTRLQIVL 406
>NP_932064
          Length = 898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AQTKLEVVL 9
           +QT+L++VL
Sbjct: 398 SQTRLQIVL 406
>XP_006720650
          Length = 729

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AQTKLEVVL 9
           +QT+L++VL
Sbjct: 398 SQTRLQIVL 406
>XP_005254559
          Length = 829

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AQTKLEVVL 9
           +QT+L++VL
Sbjct: 398 SQTRLQIVL 406
>XP_006720649
          Length = 855

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AQTKLEVVL 9
           +QT+L++VL
Sbjct: 355 SQTRLQIVL 363
>XP_005254557
          Length = 898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AQTKLEVVL 9
           +QT+L++VL
Sbjct: 398 SQTRLQIVL 406
>XP_006717095
          Length = 900

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AQTKLEVV 8
           AQTKL++V
Sbjct: 846 AQTKLQLV 853
>XP_006717094
          Length = 1069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQTKLEVV 8
            AQTKL++V
Sbjct: 1015 AQTKLQLV 1022
>XP_005251923
          Length = 1069

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1    AQTKLEVV 8
            AQTKL++V
Sbjct: 1015 AQTKLQLV 1022
>XP_005245738
          Length = 1014

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AQTKLEVV 8
           AQTKL++V
Sbjct: 950 AQTKLQLV 957
>XP_006711755
          Length = 1051

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AQTKLEVV 8
           AQTKL++V
Sbjct: 987 AQTKLQLV 994
>XP_005245737
          Length = 1051

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AQTKLEVV 8
           AQTKL++V
Sbjct: 987 AQTKLQLV 994
>NP_001135389
          Length = 1335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AQTKLEVVL 9
            +QTKL V+L
Sbjct: 1141 SQTKLTVIL 1149
>NP_060213
          Length = 782

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/9 (55%), Positives = 9/9 (100%)

Query: 1   AQTKLEVVL 9
           +QT+L++VL
Sbjct: 382 SQTRLQIVL 390
>NP_005742
          Length = 3907

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQTKLEV 7
            AQTKLE+
Sbjct: 3169 AQTKLEL 3175
>NP_671714
          Length = 3899

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQTKLEV 7
            AQTKLE+
Sbjct: 3161 AQTKLEL 3167
>NP_004437
          Length = 1512

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1    AQTKLEVVL 9
            A+TKL+ +L
Sbjct: 1397 AETKLQAIL 1405
>XP_006715890
          Length = 3860

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQTKLEV 7
            AQTKLE+
Sbjct: 3122 AQTKLEL 3128
>XP_005250160
          Length = 3939

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQTKLEV 7
            AQTKLE+
Sbjct: 3201 AQTKLEL 3207
>XP_005250159
          Length = 3952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AQTKLEV 7
            AQTKLE+
Sbjct: 3214 AQTKLEL 3220
>NP_001239553
          Length = 965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKLEVVL 9
           TKLEV++
Sbjct: 702 TKLEVII 708
>NP_066267
          Length = 4377

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AQTKLEVV 8
            +Q+KLEV+
Sbjct: 3460 SQSKLEVI 3467
>NP_001106272
          Length = 960

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKLEVVL 9
           TKLEV++
Sbjct: 697 TKLEVII 703
>NP_001106271
          Length = 968

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKLEVVL 9
           TKLEV++
Sbjct: 705 TKLEVII 711
>NP_066920
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKLEVVL 9
           TKLEV++
Sbjct: 710 TKLEVII 716
>XP_006717852
          Length = 3508

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AQTKLEVV 8
            +Q+KLEV+
Sbjct: 2591 SQSKLEVI 2598
>XP_006717851
          Length = 3513

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AQTKLEVV 8
            +Q+KLEV+
Sbjct: 2596 SQSKLEVI 2603
>XP_006717850
          Length = 4364

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AQTKLEVV 8
            +Q+KLEV+
Sbjct: 3447 SQSKLEVI 3454
>XP_006717849
          Length = 4383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AQTKLEVV 8
            +Q+KLEV+
Sbjct: 3466 SQSKLEVI 3473
>XP_006717848
          Length = 4392

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AQTKLEVV 8
            +Q+KLEV+
Sbjct: 3475 SQSKLEVI 3482
>XP_006717847
          Length = 4395

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AQTKLEVV 8
            +Q+KLEV+
Sbjct: 3478 SQSKLEVI 3485
>XP_006717846
          Length = 4396

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AQTKLEVV 8
            +Q+KLEV+
Sbjct: 3479 SQSKLEVI 3486
>XP_006717845
          Length = 4397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 1    AQTKLEVV 8
            +Q+KLEV+
Sbjct: 3480 SQSKLEVI 3487
>XP_005264571
          Length = 937

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKLEVVL 9
           TKLEV++
Sbjct: 674 TKLEVII 680
>XP_005264570
          Length = 967

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKLEVVL 9
           TKLEV++
Sbjct: 704 TKLEVII 710
>XP_006712148
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKLEVVL 9
           TKLEV++
Sbjct: 710 TKLEVII 716
>XP_006712147
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKLEVVL 9
           TKLEV++
Sbjct: 710 TKLEVII 716
>XP_006712146
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKLEVVL 9
           TKLEV++
Sbjct: 710 TKLEVII 716
>XP_006712145
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKLEVVL 9
           TKLEV++
Sbjct: 710 TKLEVII 716
>XP_006712144
          Length = 973

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKLEVVL 9
           TKLEV++
Sbjct: 710 TKLEVII 716
>XP_006712143
          Length = 996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKLEVVL 9
           TKLEV++
Sbjct: 733 TKLEVII 739
>XP_005264569
          Length = 1003

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKLEVVL 9
           TKLEV++
Sbjct: 740 TKLEVII 746
>NP_001106273
          Length = 937

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   TKLEVVL 9
           TKLEV++
Sbjct: 674 TKLEVII 680
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.127    0.288 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 330,876
Number of extensions: 354
Number of successful extensions: 58
Number of sequences better than 10000.0: 58
Number of HSP's gapped: 58
Number of HSP's successfully gapped: 58
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package