Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004251                                                              19     665
NP_004216                                                              17    2528
NP_848611                                                              17    2528
NP_071378                                                              16    5631
NP_005520                                                              16    5631
NP_003176                                                              16    5631
NP_000389                                                              16    5631
XP_005260563                                                           16    5631
XP_005260561                                                           16    5631
XP_006710661                                                           16    5631
XP_005245920                                                           16    5631
XP_006710660                                                           16    5631
XP_006710659                                                           16    5631
XP_006710658                                                           16    5631
XP_006710657                                                           16    5631
NP_001139660                                                           16    7355
NP_001073899                                                           16    7355
NP_003728                                                              16    7355
NP_075053                                                              16    7355
NP_001254757                                                           16    7355
NP_001254756                                                           16    7355
NP_714544                                                              16    7355
NP_060805                                                              16    7355
XP_005258568                                                           16    7355
XP_005255950                                                           16    7355
XP_005255949                                                           16    7355
XP_006720470                                                           16    7355
XP_006720266                                                           16    7355
XP_006720265                                                           16    7355
XP_005253264                                                           16    7355
XP_006714735                                                           16    7355
XP_005248626                                                           16    7355
NP_789781                                                              16    7355
NP_068506                                                              15    9605
NP_002451                                                              15    9605
NP_001182215                                                           15    9605
XP_006717557                                                           15    9605
XP_006717556                                                           15    9605
XP_005252630                                                           15    9605
XP_005252629                                                           15    9605
XP_005252628                                                           15    9605
XP_005252627                                                           15    9605
XP_005252625                                                           15    9605
XP_005252624                                                           15    9605
XP_005252622                                                           15    9605
XP_006717555                                                           15    9605
XP_005252621                                                           15    9605
XP_006715153                                                           15    9605
NP_857597                                                              15    9605
NP_872295                                                              15    9605
>NP_004251
          Length = 1208

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 1   AQLQALAH 8
           AQLQALAH
Sbjct: 954 AQLQALAH 961
>NP_004216
          Length = 1052

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQLQALAHM 9
           AQL ALAH+
Sbjct: 152 AQLGALAHL 160
>NP_848611
          Length = 746

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QLQALAHM 9
           QLQAL+H+
Sbjct: 129 QLQALSHL 136
>NP_071378
          Length = 1342

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLQALAH 8
            AQL+A AH
Sbjct: 1289 AQLEAAAH 1296
>NP_005520
          Length = 4391

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    QLQALAH 8
            QLQ LAH
Sbjct: 3317 QLQCLAH 3323
>NP_003176
          Length = 1085

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           AQ+QA AH
Sbjct: 474 AQMQAQAH 481
>NP_000389
          Length = 301

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1  AQLQALAHM 9
          AQL  L HM
Sbjct: 3  AQLSTLGHM 11
>XP_005260563
          Length = 1166

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLQALAH 8
            AQL+A AH
Sbjct: 1113 AQLEAAAH 1120
>XP_005260561
          Length = 1341

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1    AQLQALAH 8
            AQL+A AH
Sbjct: 1288 AQLEAAAH 1295
>XP_006710661
          Length = 4057

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    QLQALAH 8
            QLQ LAH
Sbjct: 3500 QLQCLAH 3506
>XP_005245920
          Length = 4392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    QLQALAH 8
            QLQ LAH
Sbjct: 3318 QLQCLAH 3324
>XP_006710660
          Length = 4397

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    QLQALAH 8
            QLQ LAH
Sbjct: 3317 QLQCLAH 3323
>XP_006710659
          Length = 4556

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    QLQALAH 8
            QLQ LAH
Sbjct: 3476 QLQCLAH 3482
>XP_006710658
          Length = 4563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    QLQALAH 8
            QLQ LAH
Sbjct: 3483 QLQCLAH 3489
>XP_006710657
          Length = 4579

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    QLQALAH 8
            QLQ LAH
Sbjct: 3499 QLQCLAH 3505
>NP_001139660
          Length = 571

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   QLQALAHM 9
           QLQ L HM
Sbjct: 510 QLQQLQHM 517
>NP_001073899
          Length = 576

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   QLQALAHM 9
           QLQ L HM
Sbjct: 515 QLQQLQHM 522
>NP_003728
          Length = 3298

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    QLQALAH 8
            QLQ LAH
Sbjct: 2346 QLQLLAH 2352
>NP_075053
          Length = 765

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QLQALAHM 9
           +LQAL+H+
Sbjct: 236 RLQALSHL 243
>NP_001254757
          Length = 811

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QLQALAHM 9
           QLQALA++
Sbjct: 561 QLQALANL 568
>NP_001254756
          Length = 811

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QLQALAHM 9
           QLQALA++
Sbjct: 561 QLQALANL 568
>NP_714544
          Length = 1775

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2    QLQALAHM 9
            QL+ LAH+
Sbjct: 1632 QLEVLAHL 1639
>NP_060805
          Length = 927

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QLQALAHM 9
           QLQALA++
Sbjct: 677 QLQALANL 684
>XP_005258568
          Length = 1029

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AQLQALAHM 9
           AQL+ L H+
Sbjct: 449 AQLEGLCHL 457
>XP_005255950
          Length = 572

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   QLQALAHM 9
           QLQ L HM
Sbjct: 511 QLQQLQHM 518
>XP_005255949
          Length = 575

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   QLQALAHM 9
           QLQ L HM
Sbjct: 514 QLQQLQHM 521
>XP_006720470
          Length = 1017

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   QLQALAHM 9
           QL+ LAH+
Sbjct: 874 QLEVLAHL 881
>XP_006720266
          Length = 811

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QLQALAHM 9
           QLQALA++
Sbjct: 561 QLQALANL 568
>XP_006720265
          Length = 811

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   QLQALAHM 9
           QLQALA++
Sbjct: 561 QLQALANL 568
>XP_005253264
          Length = 3443

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2    QLQALAH 8
            QLQ LAH
Sbjct: 2491 QLQLLAH 2497
>XP_006714735
          Length = 722

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QLQALAHM 9
           +LQAL+H+
Sbjct: 236 RLQALSHL 243
>XP_005248626
          Length = 724

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QLQALAHM 9
           +LQAL+H+
Sbjct: 195 RLQALSHL 202
>NP_789781
          Length = 1048

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   AQLQALAHM 9
           AQL+ L H+
Sbjct: 449 AQLEGLCHL 457
>NP_068506
          Length = 2214

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           A+LQA AH
Sbjct: 780 ARLQASAH 787
>NP_002451
          Length = 451

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           ++LQA AH
Sbjct: 366 SELQAFAH 373
>NP_001182215
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           ++LQA AH
Sbjct: 365 SELQAFAH 372
>XP_006717557
          Length = 1940

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           A+LQA AH
Sbjct: 464 ARLQASAH 471
>XP_006717556
          Length = 2024

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           A+LQA AH
Sbjct: 548 ARLQASAH 555
>XP_005252630
          Length = 2256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           A+LQA AH
Sbjct: 780 ARLQASAH 787
>XP_005252629
          Length = 2256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           A+LQA AH
Sbjct: 780 ARLQASAH 787
>XP_005252628
          Length = 2256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           A+LQA AH
Sbjct: 780 ARLQASAH 787
>XP_005252627
          Length = 2256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           A+LQA AH
Sbjct: 780 ARLQASAH 787
>XP_005252625
          Length = 2277

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           A+LQA AH
Sbjct: 801 ARLQASAH 808
>XP_005252624
          Length = 2292

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           A+LQA AH
Sbjct: 858 ARLQASAH 865
>XP_005252622
          Length = 2308

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           A+LQA AH
Sbjct: 858 ARLQASAH 865
>XP_006717555
          Length = 2328

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           A+LQA AH
Sbjct: 852 ARLQASAH 859
>XP_005252621
          Length = 2334

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           A+LQA AH
Sbjct: 858 ARLQASAH 865
>XP_006715153
          Length = 415

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AQLQALAH 8
           ++LQA AH
Sbjct: 330 SELQAFAH 337
>NP_857597
          Length = 1349

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2    QLQALAHM 9
            QLQA  HM
Sbjct: 1162 QLQAQQHM 1169
>NP_872295
          Length = 330

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 1  AQLQALAH 8
          AQLQ L H
Sbjct: 42 AQLQELEH 49
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.330    0.120    0.318 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 404,997
Number of extensions: 680
Number of successful extensions: 50
Number of sequences better than 10000.0: 50
Number of HSP's gapped: 50
Number of HSP's successfully gapped: 50
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.4 bits)
S2: 28 (15.4 bits)

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