Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_722576                                                              19     869
XP_005262424                                                           19     869
NP_149056                                                              17    4312
NP_060887                                                              16    5631
NP_001161221                                                           16    5631
XP_005245387                                                           16    5631
XP_005245386                                                           16    5631
XP_006711512                                                           16    5631
NP_067544                                                              16    7355
NP_001172019                                                           16    7355
NP_001172020                                                           16    7355
NP_000823                                                              16    7355
NP_076985                                                              16    7355
NP_015566                                                              16    7355
NP_001278261                                                           16    7355
NP_001034553                                                           16    7355
NP_005877                                                              16    7355
NP_060453                                                              16    7355
NP_001035282                                                           16    7355
NP_060303                                                              16    7355
NP_940870                                                              16    7355
XP_006725461                                                           16    7355
XP_006724090                                                           16    7355
XP_005257554                                                           16    7355
XP_006721186                                                           16    7355
XP_005255829                                                           16    7355
XP_006721185                                                           16    7355
XP_006721184                                                           16    7355
XP_005266130                                                           16    7355
XP_005266129                                                           16    7355
XP_005266128                                                           16    7355
XP_006715495                                                           16    7355
XP_006715494                                                           16    7355
XP_006715493                                                           16    7355
NP_000431                                                              15    9605
NP_005227                                                              15    9605
NP_612567                                                              15    9605
NP_003257                                                              15    9605
NP_612564                                                              15    9605
NP_783161                                                              15    9605
NP_001273742                                                           15    9605
NP_055504                                                              15    9605
NP_001277192                                                           15    9605
NP_001273743                                                           15    9605
NP_002913                                                              15    9605
NP_001273744                                                           15    9605
NP_001273746                                                           15    9605
NP_055165                                                              15    9605
NP_001071122                                                           15    9605
NP_002918                                                              15    9605
XP_005250008                                                           15    9605
XP_006715921                                                           15    9605
XP_005250007                                                           15    9605
XP_006714647                                                           15    9605
XP_006712687                                                           15    9605
XP_006712686                                                           15    9605
XP_006712685                                                           15    9605
XP_006712684                                                           15    9605
XP_006712683                                                           15    9605
XP_006712682                                                           15    9605
XP_006712681                                                           15    9605
XP_005246730                                                           15    9605
XP_005246729                                                           15    9605
XP_006712680                                                           15    9605
XP_006712679                                                           15    9605
NP_658912                                                              15    9605
NP_849150                                                              15    9605
>NP_722576
          Length = 3080

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AQKILKTLL 9
           AQKILKTL+
Sbjct: 299 AQKILKTLV 307
>XP_005262424
          Length = 2875

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AQKILKTLL 9
           AQKILKTL+
Sbjct: 94  AQKILKTLV 102
>NP_149056
          Length = 342

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  AQKILKT 7
          AQK+LKT
Sbjct: 52 AQKVLKT 58
>NP_060887
          Length = 1610

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QKILKTL 8
            QK+LKTL
Sbjct: 1112 QKLLKTL 1118
>NP_001161221
          Length = 1457

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   QKILKTL 8
           QK+LKTL
Sbjct: 959 QKLLKTL 965
>XP_005245387
          Length = 1203

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QKILKTL 8
            QK+LKTL
Sbjct: 1112 QKLLKTL 1118
>XP_005245386
          Length = 1518

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QKILKTL 8
            QK+LKTL
Sbjct: 1020 QKLLKTL 1026
>XP_006711512
          Length = 1547

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    QKILKTL 8
            QK+LKTL
Sbjct: 1112 QKLLKTL 1118
>NP_067544
          Length = 901

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           AQK L+TLL
Sbjct: 176 AQKRLETLL 184
>NP_001172019
          Length = 943

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           AQK L+TLL
Sbjct: 176 AQKRLETLL 184
>NP_001172020
          Length = 906

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           AQK L+TLL
Sbjct: 176 AQKRLETLL 184
>NP_000823
          Length = 885

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           AQK L+TLL
Sbjct: 176 AQKRLETLL 184
>NP_076985
          Length = 1104

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AQKILKTL 8
           A K+LKTL
Sbjct: 594 ASKLLKTL 601
>NP_015566
          Length = 938

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           AQK L+TLL
Sbjct: 176 AQKRLETLL 184
>NP_001278261
          Length = 841

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           +QK +KTLL
Sbjct: 664 SQKCVKTLL 672
>NP_001034553
          Length = 1323

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1    AQKILKTLL 9
            +QK +KTLL
Sbjct: 1146 SQKCVKTLL 1154
>NP_005877
          Length = 655

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           A KIL+TL+
Sbjct: 94  AAKILRTLM 102
>NP_060453
          Length = 446

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KILKTLL 9
           K+LKTLL
Sbjct: 130 KLLKTLL 136
>NP_001035282
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           AQKI +TL+
Sbjct: 337 AQKIYETLI 345
>NP_060303
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           AQKI +TL+
Sbjct: 337 AQKIYETLI 345
>NP_940870
          Length = 1243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KILKTLL 9
           K+LKTLL
Sbjct: 322 KLLKTLL 328
>XP_006725461
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           AQKI +TL+
Sbjct: 337 AQKIYETLI 345
>XP_006724090
          Length = 388

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           AQKI +TL+
Sbjct: 337 AQKIYETLI 345
>XP_005257554
          Length = 364

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3  KILKTLL 9
          K+LKTLL
Sbjct: 48 KLLKTLL 54
>XP_006721186
          Length = 658

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           A KIL+TL+
Sbjct: 94  AAKILRTLM 102
>XP_005255829
          Length = 672

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           A KIL+TL+
Sbjct: 94  AAKILRTLM 102
>XP_006721185
          Length = 675

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           A KIL+TL+
Sbjct: 94  AAKILRTLM 102
>XP_006721184
          Length = 675

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           A KIL+TL+
Sbjct: 94  AAKILRTLM 102
>XP_005266130
          Length = 959

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           AQK L+TLL
Sbjct: 176 AQKRLETLL 184
>XP_005266129
          Length = 922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           AQK L+TLL
Sbjct: 176 AQKRLETLL 184
>XP_005266128
          Length = 922

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           AQK L+TLL
Sbjct: 176 AQKRLETLL 184
>XP_006715495
          Length = 680

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KILKTLL 9
           K+LKTLL
Sbjct: 322 KLLKTLL 328
>XP_006715494
          Length = 1017

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KILKTLL 9
           K+LKTLL
Sbjct: 96  KLLKTLL 102
>XP_006715493
          Length = 1243

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KILKTLL 9
           K+LKTLL
Sbjct: 322 KLLKTLL 328
>NP_000431
          Length = 860

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   QKILKT 7
           QKILKT
Sbjct: 466 QKILKT 471
>NP_005227
          Length = 916

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   KILKTLL 9
           KIL+TLL
Sbjct: 289 KILRTLL 295
>NP_612567
          Length = 639

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKILKTLL 9
           QK+ KTLL
Sbjct: 572 QKVEKTLL 579
>NP_003257
          Length = 799

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKILKTLL 9
           QK+ KTLL
Sbjct: 732 QKVEKTLL 739
>NP_612564
          Length = 839

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   QKILKTLL 9
           QK+ KTLL
Sbjct: 772 QKVEKTLL 779
>NP_783161
          Length = 665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           A+K+LK L+
Sbjct: 653 AEKLLKNLI 661
>NP_001273742
          Length = 198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  AQKILKTLL 9
          A+KI+K L+
Sbjct: 68 AEKIIKNLI 76
>NP_055504
          Length = 2186

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AQKILKT 7
           AQKILK+
Sbjct: 536 AQKILKS 542
>NP_001277192
          Length = 2180

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AQKILKT 7
           AQKILK+
Sbjct: 530 AQKILKS 536
>NP_001273743
          Length = 210

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  AQKILKTLL 9
          A+KI+K L+
Sbjct: 80 AEKIIKNLI 88
>NP_002913
          Length = 209

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           AQK++ TL+
Sbjct: 174 AQKVIYTLM 182
>NP_001273744
          Length = 166

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  AQKILKTLL 9
          A+KI+K L+
Sbjct: 36 AEKIIKNLI 44
>NP_001273746
          Length = 166

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  AQKILKTLL 9
          A+KI+K L+
Sbjct: 36 AEKIIKNLI 44
>NP_055165
          Length = 198

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  AQKILKTLL 9
          A+KI+K L+
Sbjct: 68 AEKIIKNLI 76
>NP_001071122
          Length = 188

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  AQKILKTLL 9
          A+KI+K L+
Sbjct: 58 AEKIIKNLI 66
>NP_002918
          Length = 159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QKILKTL 8
           QK+LKT+
Sbjct: 147 QKLLKTM 153
>XP_005250008
          Length = 456

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           A+K+LK L+
Sbjct: 444 AEKLLKNLI 452
>XP_006715921
          Length = 665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           A+K+LK L+
Sbjct: 653 AEKLLKNLI 661
>XP_005250007
          Length = 665

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AQKILKTLL 9
           A+K+LK L+
Sbjct: 653 AEKLLKNLI 661
>XP_006714647
          Length = 201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1  AQKILKTLL 9
          A+KI+K L+
Sbjct: 71 AEKIIKNLI 79
>XP_006712687
          Length = 2166

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AQKILKT 7
           AQKILK+
Sbjct: 549 AQKILKS 555
>XP_006712686
          Length = 2173

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AQKILKT 7
           AQKILK+
Sbjct: 549 AQKILKS 555
>XP_006712685
          Length = 2175

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AQKILKT 7
           AQKILK+
Sbjct: 549 AQKILKS 555
>XP_006712684
          Length = 2189

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AQKILKT 7
           AQKILK+
Sbjct: 530 AQKILKS 536
>XP_006712683
          Length = 2195

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AQKILKT 7
           AQKILK+
Sbjct: 536 AQKILKS 542
>XP_006712682
          Length = 2199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AQKILKT 7
           AQKILK+
Sbjct: 549 AQKILKS 555
>XP_006712681
          Length = 2199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AQKILKT 7
           AQKILK+
Sbjct: 549 AQKILKS 555
>XP_005246730
          Length = 2199

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AQKILKT 7
           AQKILK+
Sbjct: 549 AQKILKS 555
>XP_005246729
          Length = 2201

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AQKILKT 7
           AQKILK+
Sbjct: 549 AQKILKS 555
>XP_006712680
          Length = 2206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AQKILKT 7
           AQKILK+
Sbjct: 549 AQKILKS 555
>XP_006712679
          Length = 2208

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AQKILKT 7
           AQKILK+
Sbjct: 549 AQKILKS 555
>NP_658912
          Length = 159

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   QKILKTL 8
           QK+LKT+
Sbjct: 147 QKLLKTM 153
>NP_849150
          Length = 1445

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2   QKILKTLL 9
           QK+L+TL+
Sbjct: 362 QKLLETLI 369
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.137    0.320 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 382,325
Number of extensions: 674
Number of successful extensions: 67
Number of sequences better than 10000.0: 67
Number of HSP's gapped: 67
Number of HSP's successfully gapped: 67
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)

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