Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              20     509
NP_009297                                                              20     509
NP_003172                                                              16    5631
NP_001193583                                                           16    5631
NP_006303                                                              16    5631
NP_001257413                                                           16    5631
NP_001070729                                                           16    5631
NP_001161328                                                           16    5631
NP_060653                                                              16    5631
NP_001177369                                                           16    5631
NP_006302                                                              16    5631
NP_001002844                                                           16    5631
NP_001275517                                                           16    5631
NP_001275518                                                           16    5631
NP_001002843                                                           16    5631
NP_060131                                                              16    5631
XP_005256932                                                           16    5631
XP_006721667                                                           16    5631
XP_005256931                                                           16    5631
XP_005256930                                                           16    5631
XP_006721666                                                           16    5631
XP_005256929                                                           16    5631
XP_005256928                                                           16    5631
XP_006721665                                                           16    5631
XP_005256925                                                           16    5631
XP_005256924                                                           16    5631
XP_006721664                                                           16    5631
XP_005256923                                                           16    5631
XP_006720644                                                           16    5631
XP_005254542                                                           16    5631
XP_005254541                                                           16    5631
XP_005254540                                                           16    5631
XP_005254538                                                           16    5631
XP_006709992                                                           16    5631
XP_005253633                                                           16    5631
XP_005253632                                                           16    5631
XP_006719537                                                           16    5631
XP_006719536                                                           16    5631
XP_005253630                                                           16    5631
XP_005253629                                                           16    5631
XP_006710191                                                           16    5631
NP_001010854                                                           16    7355
NP_002846                                                              16    7355
NP_060910                                                              16    7355
NP_001406                                                              16    7355
NP_976030                                                              16    7355
NP_976031                                                              16    7355
XP_006716525                                                           16    7355
XP_006716524                                                           16    7355
NP_001238892                                                           15    9605
NP_001238891                                                           15    9605
NP_002290                                                              15    9605
NP_002356                                                              15    9605
NP_060587                                                              15    9605
NP_056410                                                              15    9605
NP_001009959                                                           15    9605
NP_065762                                                              15    9605
XP_006725061                                                           15    9605
XP_005274567                                                           15    9605
XP_005270021                                                           15    9605
XP_005270020                                                           15    9605
XP_005270019                                                           15    9605
>NP_005148
          Length = 1130

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ANGAITKGV 9
            A+GAITKGV
Sbjct: 1023 ASGAITKGV 1031
>NP_009297
          Length = 1149

 Score = 19.6 bits (39), Expect =   509
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    ANGAITKGV 9
            A+GAITKGV
Sbjct: 1042 ASGAITKGV 1050
>NP_003172
          Length = 435

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ANGAITKG 8
           +NGA+T G
Sbjct: 354 SNGAVTPG 361
>NP_001193583
          Length = 2504

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GAITKGV 9
            G+ITKG+
Sbjct: 1196 GSITKGI 1202
>NP_006303
          Length = 2514

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GAITKGV 9
            G+ITKG+
Sbjct: 1206 GSITKGI 1212
>NP_001257413
          Length = 377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   ANGAITKG 8
           +NGA+T G
Sbjct: 296 SNGAVTPG 303
>NP_001070729
          Length = 2458

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3    GAITKGV 9
            G+ITKG+
Sbjct: 1196 GSITKGI 1202
>NP_001161328
          Length = 1393

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NGAITKGV 9
           NG++ KGV
Sbjct: 389 NGSVKKGV 396
>NP_060653
          Length = 1392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NGAITKGV 9
           NG++ KGV
Sbjct: 388 NGSVKKGV 395
>NP_001177369
          Length = 2337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    GAITKG 8
            GAITKG
Sbjct: 1346 GAITKG 1351
>NP_006302
          Length = 2440

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    GAITKG 8
            GAITKG
Sbjct: 1330 GAITKG 1335
>NP_001002844
          Length = 158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  NGAITKGV 9
          NGA+++G+
Sbjct: 75 NGALSRGI 82
>NP_001275517
          Length = 979

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  NGAITKGV 9
          NGA+++G+
Sbjct: 75 NGALSRGI 82
>NP_001275518
          Length = 158

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  NGAITKGV 9
          NGA+++G+
Sbjct: 75 NGALSRGI 82
>NP_001002843
          Length = 966

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  NGAITKGV 9
          NGA+++G+
Sbjct: 62 NGALSRGI 69
>NP_060131
          Length = 979

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2  NGAITKGV 9
          NGA+++G+
Sbjct: 75 NGALSRGI 82
>XP_005256932
          Length = 2448

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    GAITKG 8
            GAITKG
Sbjct: 1414 GAITKG 1419
>XP_006721667
          Length = 2456

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    GAITKG 8
            GAITKG
Sbjct: 1346 GAITKG 1351
>XP_005256931
          Length = 2466

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    GAITKG 8
            GAITKG
Sbjct: 1356 GAITKG 1361
>XP_005256930
          Length = 2508

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    GAITKG 8
            GAITKG
Sbjct: 1398 GAITKG 1403
>XP_006721666
          Length = 2511

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    GAITKG 8
            GAITKG
Sbjct: 1414 GAITKG 1419
>XP_005256929
          Length = 2514

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    GAITKG 8
            GAITKG
Sbjct: 1404 GAITKG 1409
>XP_005256928
          Length = 2515

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    GAITKG 8
            GAITKG
Sbjct: 1405 GAITKG 1410
>XP_006721665
          Length = 2523

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    GAITKG 8
            GAITKG
Sbjct: 1413 GAITKG 1418
>XP_005256925
          Length = 2523

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    GAITKG 8
            GAITKG
Sbjct: 1413 GAITKG 1418
>XP_005256924
          Length = 2524

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    GAITKG 8
            GAITKG
Sbjct: 1414 GAITKG 1419
>XP_006721664
          Length = 2524

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    GAITKG 8
            GAITKG
Sbjct: 1414 GAITKG 1419
>XP_005256923
          Length = 2524

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3    GAITKG 8
            GAITKG
Sbjct: 1414 GAITKG 1419
>XP_006720644
          Length = 699

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   NGAITKGV 9
           NGA+++G+
Sbjct: 239 NGALSRGI 246
>XP_005254542
          Length = 756

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   NGAITKGV 9
           NGA+++G+
Sbjct: 239 NGALSRGI 246
>XP_005254541
          Length = 890

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   NGAITKGV 9
           NGA+++G+
Sbjct: 239 NGALSRGI 246
>XP_005254540
          Length = 924

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   NGAITKGV 9
           NGA+++G+
Sbjct: 239 NGALSRGI 246
>XP_005254538
          Length = 993

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   NGAITKGV 9
           NGA+++G+
Sbjct: 239 NGALSRGI 246
>XP_006709992
          Length = 1311

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ANGAITKGV 9
           ANG  TKG+
Sbjct: 914 ANGDATKGM 922
>XP_005253633
          Length = 1392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NGAITKGV 9
           NG++ KGV
Sbjct: 388 NGSVKKGV 395
>XP_005253632
          Length = 1392

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NGAITKGV 9
           NG++ KGV
Sbjct: 388 NGSVKKGV 395
>XP_006719537
          Length = 1393

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NGAITKGV 9
           NG++ KGV
Sbjct: 389 NGSVKKGV 396
>XP_006719536
          Length = 1393

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NGAITKGV 9
           NG++ KGV
Sbjct: 389 NGSVKKGV 396
>XP_005253630
          Length = 1393

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NGAITKGV 9
           NG++ KGV
Sbjct: 389 NGSVKKGV 396
>XP_005253629
          Length = 1393

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NGAITKGV 9
           NG++ KGV
Sbjct: 389 NGSVKKGV 396
>XP_006710191
          Length = 1582

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1    ANGAITKGV 9
            ANG  TKG+
Sbjct: 1297 ANGDATKGM 1305
>NP_001010854
          Length = 843

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NGAITKGV 9
           NG +T+GV
Sbjct: 232 NGNLTRGV 239
>NP_002846
          Length = 517

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NGAITKGV 9
           NG++ KGV
Sbjct: 286 NGSLPKGV 293
>NP_060910
          Length = 432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  NGAITKG 8
          NGA+T G
Sbjct: 84 NGALTNG 90
>NP_001406
          Length = 472

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   ANGAITKGV 9
           A G+I KGV
Sbjct: 279 AGGSILKGV 287
>NP_976030
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NGAITKGV 9
           NG++ KGV
Sbjct: 286 NGSLPKGV 293
>NP_976031
          Length = 352

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   NGAITKGV 9
           NG++ KGV
Sbjct: 286 NGSLPKGV 293
>XP_006716525
          Length = 432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  NGAITKG 8
          NGA+T G
Sbjct: 84 NGALTNG 90
>XP_006716524
          Length = 432

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2  NGAITKG 8
          NGA+T G
Sbjct: 84 NGALTNG 90
>NP_001238892
          Length = 791

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ANGAIT 6
           ANGA+T
Sbjct: 129 ANGAVT 134
>NP_001238891
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ANGAIT 6
           ANGA+T
Sbjct: 129 ANGAVT 134
>NP_002290
          Length = 1927

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   NGAITKG 8
           NG +TKG
Sbjct: 845 NGFLTKG 851
>NP_002356
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   NGAITKG 8
           NG +T+G
Sbjct: 189 NGTVTRG 195
>NP_060587
          Length = 1224

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1    ANGAITKGV 9
            ANG + +GV
Sbjct: 1059 ANGKLAEGV 1067
>NP_056410
          Length = 871

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ANGAIT 6
           ANGA+T
Sbjct: 129 ANGAVT 134
>NP_001009959
          Length = 297

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  GAITKG 8
          GA+TKG
Sbjct: 64 GALTKG 69
>NP_065762
          Length = 284

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3  GAITKG 8
          GA+TKG
Sbjct: 51 GALTKG 56
>XP_006725061
          Length = 904

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   ANGAIT 6
           ANGA+T
Sbjct: 129 ANGAVT 134
>XP_005274567
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/7 (57%), Positives = 6/7 (85%)

Query: 2   NGAITKG 8
           NG +T+G
Sbjct: 189 NGTVTRG 195
>XP_005270021
          Length = 753

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ANGAITKGV 9
           ANG + +GV
Sbjct: 588 ANGKLAEGV 596
>XP_005270020
          Length = 965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ANGAITKGV 9
           ANG + +GV
Sbjct: 800 ANGKLAEGV 808
>XP_005270019
          Length = 965

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 7/9 (77%)

Query: 1   ANGAITKGV 9
           ANG + +GV
Sbjct: 800 ANGKLAEGV 808
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.128    0.343 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 526,552
Number of extensions: 963
Number of successful extensions: 62
Number of sequences better than 10000.0: 62
Number of HSP's gapped: 62
Number of HSP's successfully gapped: 62
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.4 bits)
S2: 28 (15.4 bits)

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