Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000537                                                              19     665
NP_001263689                                                           19     665
NP_001119584                                                           19     665
NP_001119586                                                           19     665
NP_001263625                                                           19     665
NP_001119590                                                           19     665
NP_001263690                                                           19     665
NP_001119585                                                           19     665
NP_001263624                                                           19     665
NP_001119588                                                           19     665
NP_001119587                                                           19     665
NP_001119589                                                           19     665
NP_001263627                                                           19     665
NP_001263628                                                           19     665
NP_001263626                                                           19     665
NP_001108451                                                           18    1935
NP_001108454                                                           18    1935
NP_003713                                                              18    1935
NP_001108450                                                           18    1935
NP_001108452                                                           18    1935
NP_001108453                                                           18    1935
NP_001191121                                                           18    1935
NP_001119713                                                           18    1935
NP_001191117                                                           18    1935
NP_001119712                                                           18    1935
NP_001119714                                                           18    1935
NP_005418                                                              18    1935
NP_001191116                                                           18    1935
NP_001191115                                                           18    1935
NP_001191119                                                           18    1935
NP_001191113                                                           18    1935
NP_001191118                                                           18    1935
NP_001191120                                                           18    1935
NP_001191114                                                           18    1935
NP_001035519                                                           18    1935
XP_005266415                                                           18    1935
XP_005266414                                                           18    1935
XP_005247903                                                           18    1935
XP_005247901                                                           18    1935
XP_005247900                                                           18    1935
NP_001139114                                                           16    7355
NP_055502                                                              16    7355
NP_001138584                                                           16    7355
NP_001265617                                                           16    7355
XP_006720494                                                           16    7355
XP_005254281                                                           16    7355
XP_006717747                                                           16    7355
XP_006713894                                                           16    7355
XP_006713893                                                           16    7355
XP_006713892                                                           16    7355
XP_005269431                                                           16    7355
XP_006713891                                                           16    7355
XP_006713890                                                           16    7355
NP_976221                                                              15    9605
NP_001230829                                                           15    9605
NP_005327                                                              15    9605
NP_001257881                                                           15    9605
NP_001123572                                                           15    9605
NP_001123571                                                           15    9605
NP_005541                                                              15    9605
NP_005993                                                              15    9605
XP_006721253                                                           15    9605
XP_005256003                                                           15    9605
XP_005256002                                                           15    9605
XP_005256001                                                           15    9605
XP_006721252                                                           15    9605
XP_005256000                                                           15    9605
XP_005255994                                                           15    9605
XP_006721251                                                           15    9605
XP_006712539                                                           15    9605
XP_005247059                                                           15    9605
XP_005247058                                                           15    9605
XP_006712538                                                           15    9605
XP_005247060                                                           15    9605
XP_005247057                                                           15    9605
>NP_000537
          Length = 393

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           LIRVEGNL
Sbjct: 194 LIRVEGNL 201
>NP_001263689
          Length = 354

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           LIRVEGNL
Sbjct: 155 LIRVEGNL 162
>NP_001119584
          Length = 393

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           LIRVEGNL
Sbjct: 194 LIRVEGNL 201
>NP_001119586
          Length = 341

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           LIRVEGNL
Sbjct: 194 LIRVEGNL 201
>NP_001263625
          Length = 302

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           LIRVEGNL
Sbjct: 155 LIRVEGNL 162
>NP_001119590
          Length = 354

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           LIRVEGNL
Sbjct: 155 LIRVEGNL 162
>NP_001263690
          Length = 354

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           LIRVEGNL
Sbjct: 155 LIRVEGNL 162
>NP_001119585
          Length = 346

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           LIRVEGNL
Sbjct: 194 LIRVEGNL 201
>NP_001263624
          Length = 307

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           LIRVEGNL
Sbjct: 155 LIRVEGNL 162
>NP_001119588
          Length = 209

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LIRVEGNL 9
          LIRVEGNL
Sbjct: 62 LIRVEGNL 69
>NP_001119587
          Length = 261

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LIRVEGNL 9
          LIRVEGNL
Sbjct: 62 LIRVEGNL 69
>NP_001119589
          Length = 214

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LIRVEGNL 9
          LIRVEGNL
Sbjct: 62 LIRVEGNL 69
>NP_001263627
          Length = 182

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LIRVEGNL 9
          LIRVEGNL
Sbjct: 35 LIRVEGNL 42
>NP_001263628
          Length = 187

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LIRVEGNL 9
          LIRVEGNL
Sbjct: 35 LIRVEGNL 42
>NP_001263626
          Length = 234

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2  LIRVEGNL 9
          LIRVEGNL
Sbjct: 35 LIRVEGNL 42
>NP_001108451
          Length = 487

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 264 LIRVEGN 270
>NP_001108454
          Length = 393

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 170 LIRVEGN 176
>NP_003713
          Length = 680

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 264 LIRVEGN 270
>NP_001108450
          Length = 555

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 264 LIRVEGN 270
>NP_001108452
          Length = 586

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 170 LIRVEGN 176
>NP_001108453
          Length = 461

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 170 LIRVEGN 176
>NP_001191121
          Length = 565

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 143 LIRVEGN 149
>NP_001119713
          Length = 450

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 165 LIRVEGN 171
>NP_001191117
          Length = 540

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 214 LIRVEGN 220
>NP_001119712
          Length = 587

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 165 LIRVEGN 171
>NP_001119714
          Length = 426

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 165 LIRVEGN 171
>NP_005418
          Length = 636

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 214 LIRVEGN 220
>NP_001191116
          Length = 555

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 214 LIRVEGN 220
>NP_001191115
          Length = 403

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 214 LIRVEGN 220
>NP_001191119
          Length = 506

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 165 LIRVEGN 171
>NP_001191113
          Length = 499

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 214 LIRVEGN 220
>NP_001191118
          Length = 354

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 165 LIRVEGN 171
>NP_001191120
          Length = 491

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 165 LIRVEGN 171
>NP_001191114
          Length = 475

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 214 LIRVEGN 220
>NP_001035519
          Length = 1159

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           LIRV+GNL
Sbjct: 302 LIRVKGNL 309
>XP_005266415
          Length = 1158

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           LIRV+GNL
Sbjct: 302 LIRVKGNL 309
>XP_005266414
          Length = 1159

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           LIRV+GNL
Sbjct: 302 LIRVKGNL 309
>XP_005247903
          Length = 483

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 264 LIRVEGN 270
>XP_005247901
          Length = 663

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 247 LIRVEGN 253
>XP_005247900
          Length = 676

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIRVEGN
Sbjct: 264 LIRVEGN 270
>NP_001139114
          Length = 927

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IRVEGNL 9
           IRV GNL
Sbjct: 640 IRVRGNL 646
>NP_055502
          Length = 972

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IRVEGNL 9
           IRV GNL
Sbjct: 685 IRVRGNL 691
>NP_001138584
          Length = 543

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ALIRVEGNL 9
           +++R+EG+L
Sbjct: 259 SVVRIEGSL 267
>NP_001265617
          Length = 631

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RVEGNL 9
           R+EGNL
Sbjct: 441 RIEGNL 446
>XP_006720494
          Length = 478

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ALIRVEGNL 9
           +++R+EG+L
Sbjct: 172 SVVRIEGSL 180
>XP_005254281
          Length = 565

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   ALIRVEGNL 9
           +++R+EG+L
Sbjct: 259 SVVRIEGSL 267
>XP_006717747
          Length = 601

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 4   RVEGNL 9
           R+EGNL
Sbjct: 411 RIEGNL 416
>XP_006713894
          Length = 845

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IRVEGNL 9
           IRV GNL
Sbjct: 558 IRVRGNL 564
>XP_006713893
          Length = 845

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IRVEGNL 9
           IRV GNL
Sbjct: 558 IRVRGNL 564
>XP_006713892
          Length = 952

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IRVEGNL 9
           IRV GNL
Sbjct: 665 IRVRGNL 671
>XP_005269431
          Length = 987

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IRVEGNL 9
           IRV GNL
Sbjct: 700 IRVRGNL 706
>XP_006713891
          Length = 997

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IRVEGNL 9
           IRV GNL
Sbjct: 710 IRVRGNL 716
>XP_006713890
          Length = 1012

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   IRVEGNL 9
           IRV GNL
Sbjct: 725 IRVRGNL 731
>NP_976221
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIR+EG+
Sbjct: 480 LIRIEGD 486
>NP_001230829
          Length = 1235

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIR+EG+
Sbjct: 447 LIRIEGD 453
>NP_005327
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIR+EG+
Sbjct: 480 LIRIEGD 486
>NP_001257881
          Length = 194

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ALIRVEGNL 9
           AL+ V+G+L
Sbjct: 136 ALVHVDGHL 144
>NP_001123572
          Length = 826

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           L+R++GN+
Sbjct: 439 LVRLKGNI 446
>NP_001123571
          Length = 687

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           L+R++GN+
Sbjct: 300 LVRLKGNI 307
>NP_005541
          Length = 833

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           L+R++GN+
Sbjct: 439 LVRLKGNI 446
>NP_005993
          Length = 230

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   ALIRVEGNL 9
           AL+ V+G+L
Sbjct: 172 ALVHVDGHL 180
>XP_006721253
          Length = 828

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           L+R++GN+
Sbjct: 434 LVRLKGNI 441
>XP_005256003
          Length = 768

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           L+R++GN+
Sbjct: 381 LVRLKGNI 388
>XP_005256002
          Length = 769

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           L+R++GN+
Sbjct: 382 LVRLKGNI 389
>XP_005256001
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           L+R++GN+
Sbjct: 381 LVRLKGNI 388
>XP_006721252
          Length = 775

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           L+R++GN+
Sbjct: 381 LVRLKGNI 388
>XP_005256000
          Length = 776

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           L+R++GN+
Sbjct: 382 LVRLKGNI 389
>XP_005255994
          Length = 996

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           L+R++GN+
Sbjct: 602 LVRLKGNI 609
>XP_006721251
          Length = 1022

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   LIRVEGNL 9
           L+R++GN+
Sbjct: 628 LVRLKGNI 635
>XP_006712539
          Length = 1250

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIR+EG+
Sbjct: 480 LIRIEGD 486
>XP_005247059
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIR+EG+
Sbjct: 480 LIRIEGD 486
>XP_005247058
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIR+EG+
Sbjct: 480 LIRIEGD 486
>XP_006712538
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIR+EG+
Sbjct: 480 LIRIEGD 486
>XP_005247060
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIR+EG+
Sbjct: 480 LIRIEGD 486
>XP_005247057
          Length = 1268

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   LIRVEGN 8
           LIR+EG+
Sbjct: 480 LIRIEGD 486
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.324    0.146    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 570,939
Number of extensions: 970
Number of successful extensions: 75
Number of sequences better than 10000.0: 75
Number of HSP's gapped: 75
Number of HSP's successfully gapped: 75
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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