Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000042                                                              20     390
XP_005271621                                                           20     390
XP_006718907                                                           20     390
XP_006718906                                                           20     390
XP_005271619                                                           20     390
XP_005271618                                                           20     390
NP_001013757                                                           17    3301
NP_000013                                                              17    4312
XP_005260293                                                           17    4312
XP_006723742                                                           17    4312
NP_004993                                                              16    5631
NP_003256                                                              16    7355
NP_036565                                                              16    7355
NP_872420                                                              16    7355
NP_057480                                                              16    7355
XP_005254498                                                           16    7355
XP_006720628                                                           16    7355
XP_006720049                                                           16    7355
XP_005272472                                                           16    7355
XP_006720048                                                           16    7355
XP_005272471                                                           16    7355
XP_006720047                                                           16    7355
XP_006720046                                                           16    7355
XP_005272470                                                           16    7355
XP_006720045                                                           16    7355
XP_006715752                                                           16    7355
XP_006714357                                                           16    7355
XP_005246485                                                           16    7355
NP_001347                                                              15    9605
NP_001180346                                                           15    9605
NP_001180345                                                           15    9605
NP_001171864                                                           15    9605
NP_053586                                                              15    9605
NP_053584                                                              15    9605
NP_004874                                                              15    9605
NP_053585                                                              15    9605
NP_699204                                                              15    9605
NP_056009                                                              15    9605
NP_001265275                                                           15    9605
NP_001273384                                                           15    9605
NP_068764                                                              15    9605
XP_005258921                                                           15    9605
XP_006723252                                                           15    9605
XP_006715228                                                           15    9605
XP_005249342                                                           15    9605
XP_005266059                                                           15    9605
XP_006714988                                                           15    9605
XP_006714987                                                           15    9605
XP_006714873                                                           15    9605
XP_006714872                                                           15    9605
XP_006714871                                                           15    9605
NP_056297                                                              15    9605
NP_001073925                                                           15    9605
>NP_000042
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    AILNVIGKD 9
            AILNV+GKD
Sbjct: 1059 AILNVMGKD 1067
>XP_005271621
          Length = 2708

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AILNVIGKD 9
           AILNV+GKD
Sbjct: 711 AILNVMGKD 719
>XP_006718907
          Length = 3050

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    AILNVIGKD 9
            AILNV+GKD
Sbjct: 1053 AILNVMGKD 1061
>XP_006718906
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    AILNVIGKD 9
            AILNV+GKD
Sbjct: 1059 AILNVMGKD 1067
>XP_005271619
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    AILNVIGKD 9
            AILNV+GKD
Sbjct: 1059 AILNVMGKD 1067
>XP_005271618
          Length = 3056

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    AILNVIGKD 9
            AILNV+GKD
Sbjct: 1059 AILNVMGKD 1067
>NP_001013757
          Length = 432

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AILNVIGKD 9
           AI N+IG+D
Sbjct: 271 AIENIIGRD 279
>NP_000013
          Length = 363

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ILNVIGKD 9
          +LNVIG D
Sbjct: 46 LLNVIGMD 53
>XP_005260293
          Length = 339

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ILNVIGKD 9
          +LNVIG D
Sbjct: 46 LLNVIGMD 53
>XP_006723742
          Length = 354

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2  ILNVIGKD 9
          +LNVIG D
Sbjct: 46 LLNVIGMD 53
>NP_004993
          Length = 377

 Score = 16.2 bits (30), Expect =  5631
 Identities = 4/8 (50%), Positives = 8/8 (100%)

Query: 2   ILNVIGKD 9
           ++N+IG+D
Sbjct: 126 VINLIGRD 133
>NP_003256
          Length = 904

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LNVIGKD 9
           LNV+G D
Sbjct: 286 LNVVGND 292
>NP_036565
          Length = 1304

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AILNVIG 7
            AI+NVIG
Sbjct: 999  AIVNVIG 1005
>NP_872420
          Length = 326

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AILNVIG 7
           A+LNV+G
Sbjct: 200 AVLNVLG 206
>NP_057480
          Length = 466

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LNVIGKD 9
           LN++G+D
Sbjct: 390 LNILGRD 396
>XP_005254498
          Length = 466

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LNVIGKD 9
           LN++G+D
Sbjct: 390 LNILGRD 396
>XP_006720628
          Length = 466

 Score = 15.8 bits (29), Expect =  7355
 Identities = 4/7 (57%), Positives = 7/7 (100%)

Query: 3   LNVIGKD 9
           LN++G+D
Sbjct: 390 LNILGRD 396
>XP_006720049
          Length = 237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AILNVIG 7
           A+LNV+G
Sbjct: 111 AVLNVLG 117
>XP_005272472
          Length = 237

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AILNVIG 7
           A+LNV+G
Sbjct: 111 AVLNVLG 117
>XP_006720048
          Length = 311

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AILNVIG 7
           A+LNV+G
Sbjct: 233 AVLNVLG 239
>XP_005272471
          Length = 328

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AILNVIG 7
           A+LNV+G
Sbjct: 202 AVLNVLG 208
>XP_006720047
          Length = 329

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AILNVIG 7
           A+LNV+G
Sbjct: 203 AVLNVLG 209
>XP_006720046
          Length = 331

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AILNVIG 7
           A+LNV+G
Sbjct: 205 AVLNVLG 211
>XP_005272470
          Length = 357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AILNVIG 7
           A+LNV+G
Sbjct: 231 AVLNVLG 237
>XP_006720045
          Length = 359

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 1   AILNVIG 7
           A+LNV+G
Sbjct: 233 AVLNVLG 239
>XP_006715752
          Length = 1225

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   ILNVIGKD 9
           +LN IGK+
Sbjct: 592 LLNTIGKE 599
>XP_006714357
          Length = 904

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   LNVIGKD 9
           LNV+G D
Sbjct: 286 LNVVGND 292
>XP_005246485
          Length = 1158

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AILNVIG 7
           AI+NVIG
Sbjct: 853 AIVNVIG 859
>NP_001347
          Length = 662

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   ILNVIGKD 9
           +LN  GKD
Sbjct: 434 LLNATGKD 441
>NP_001180346
          Length = 646

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   ILNVIGKD 9
           +LN  GKD
Sbjct: 418 LLNATGKD 425
>NP_001180345
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 6/8 (75%)

Query: 2   ILNVIGKD 9
           +LN  GKD
Sbjct: 434 LLNATGKD 441
>NP_001171864
          Length = 784

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NVIGKD 9
           N++GKD
Sbjct: 315 NILGKD 320
>NP_053586
          Length = 852

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NVIGKD 9
           N++GKD
Sbjct: 315 NILGKD 320
>NP_053584
          Length = 844

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NVIGKD 9
           N++GKD
Sbjct: 315 NILGKD 320
>NP_004874
          Length = 850

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NVIGKD 9
           N++GKD
Sbjct: 315 NILGKD 320
>NP_053585
          Length = 858

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NVIGKD 9
           N++GKD
Sbjct: 315 NILGKD 320
>NP_699204
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AILNVIGKD 9
           A+LNV+ K+
Sbjct: 322 AVLNVLEKE 330
>NP_056009
          Length = 1006

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/8 (50%), Positives = 7/8 (87%)

Query: 2  ILNVIGKD 9
          +LN+ G+D
Sbjct: 54 LLNIYGRD 61
>NP_001265275
          Length = 409

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AILNVIGKD 9
           A+LNV+ K+
Sbjct: 281 AVLNVLEKE 289
>NP_001273384
          Length = 405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILNVIGK 8
           +LN+IGK
Sbjct: 232 LLNLIGK 238
>NP_068764
          Length = 405

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILNVIGK 8
           +LN+IGK
Sbjct: 232 LLNLIGK 238
>XP_005258921
          Length = 495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   AILNVIGKD 9
           +I+N++GK+
Sbjct: 129 SIVNLLGKE 137
>XP_006723252
          Length = 495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   AILNVIGKD 9
           +I+N++GK+
Sbjct: 129 SIVNLLGKE 137
>XP_006715228
          Length = 397

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILNVIGK 8
           +LN+IGK
Sbjct: 216 LLNLIGK 222
>XP_005249342
          Length = 694

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILNVIGK 8
           +LN+IGK
Sbjct: 513 LLNLIGK 519
>XP_005266059
          Length = 252

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AILNVIGKD 9
           A+LNV+ K+
Sbjct: 124 AVLNVLEKE 132
>XP_006714988
          Length = 408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AILNVIGKD 9
           A+LNV+ K+
Sbjct: 280 AVLNVLEKE 288
>XP_006714987
          Length = 409

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AILNVIGKD 9
           A+LNV+ K+
Sbjct: 281 AVLNVLEKE 289
>XP_006714873
          Length = 422

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NVIGKD 9
           N++GKD
Sbjct: 315 NILGKD 320
>XP_006714872
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NVIGKD 9
           N++GKD
Sbjct: 315 NILGKD 320
>XP_006714871
          Length = 647

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 4   NVIGKD 9
           N++GKD
Sbjct: 112 NILGKD 117
>NP_056297
          Length = 686

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ILNVIGK 8
           +LN+IGK
Sbjct: 513 LLNLIGK 519
>NP_001073925
          Length = 495

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/9 (44%), Positives = 9/9 (100%)

Query: 1   AILNVIGKD 9
           +I+N++GK+
Sbjct: 129 SIVNLLGKE 137
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.147    0.391 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 480,838
Number of extensions: 901
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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