Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_003963                                                              17    2528
XP_005270323                                                           17    2528
XP_005270322                                                           17    2528
NP_004351                                                              17    3301
NP_036222                                                              16    5631
XP_006710603                                                           16    5631
XP_006710602                                                           16    5631
XP_006710600                                                           16    5631
XP_005270757                                                           16    5631
XP_006710599                                                           16    5631
XP_006710598                                                           16    5631
XP_006710597                                                           16    5631
XP_006710596                                                           16    5631
XP_006710595                                                           16    5631
XP_006710594                                                           16    5631
XP_006710593                                                           16    5631
XP_006710592                                                           16    5631
XP_006710591                                                           16    5631
XP_006710590                                                           16    5631
XP_006710589                                                           16    5631
XP_006710588                                                           16    5631
XP_006710587                                                           16    5631
XP_006710586                                                           16    5631
XP_006710585                                                           16    5631
XP_005270755                                                           16    5631
XP_006710584                                                           16    5631
XP_005270754                                                           16    5631
XP_005270753                                                           16    5631
XP_006710583                                                           16    5631
XP_005270752                                                           16    5631
XP_006710582                                                           16    5631
XP_005270751                                                           16    5631
NP_004221                                                              15    9605
XP_006722999                                                           15    9605
>NP_003963
          Length = 1849

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IANTILSQ 9
            IANT++SQ
Sbjct: 1774 IANTVISQ 1781
>XP_005270323
          Length = 1519

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IANTILSQ 9
            IANT++SQ
Sbjct: 1444 IANTVISQ 1451
>XP_005270322
          Length = 1646

 Score = 17.3 bits (33), Expect =  2528
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2    IANTILSQ 9
            IANT++SQ
Sbjct: 1571 IANTVISQ 1578
>NP_004351
          Length = 882

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AIANTILSQ 9
           AIA TILSQ
Sbjct: 299 AIAYTILSQ 307
>NP_036222
          Length = 5430

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 4516 ILNTVLSQ 4523
>XP_006710603
          Length = 5324

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 4404 ILNTVLSQ 4411
>XP_006710602
          Length = 7391

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6471 ILNTVLSQ 6478
>XP_006710600
          Length = 5384

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 4404 ILNTVLSQ 4411
>XP_005270757
          Length = 5460

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 4546 ILNTVLSQ 4553
>XP_006710599
          Length = 5656

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 4676 ILNTVLSQ 4683
>XP_006710598
          Length = 7553

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6573 ILNTVLSQ 6580
>XP_006710597
          Length = 7451

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6471 ILNTVLSQ 6478
>XP_006710596
          Length = 7512

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6532 ILNTVLSQ 6539
>XP_006710595
          Length = 7526

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6546 ILNTVLSQ 6553
>XP_006710594
          Length = 7528

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6548 ILNTVLSQ 6555
>XP_006710593
          Length = 7539

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6559 ILNTVLSQ 6566
>XP_006710592
          Length = 7544

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6564 ILNTVLSQ 6571
>XP_006710591
          Length = 7558

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6578 ILNTVLSQ 6585
>XP_006710590
          Length = 7563

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6583 ILNTVLSQ 6590
>XP_006710589
          Length = 7595

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6615 ILNTVLSQ 6622
>XP_006710588
          Length = 7614

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6634 ILNTVLSQ 6641
>XP_006710587
          Length = 7645

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6665 ILNTVLSQ 6672
>XP_006710586
          Length = 7645

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6743 ILNTVLSQ 6750
>XP_006710585
          Length = 7657

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6743 ILNTVLSQ 6750
>XP_005270755
          Length = 7663

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6743 ILNTVLSQ 6750
>XP_006710584
          Length = 7686

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6743 ILNTVLSQ 6750
>XP_005270754
          Length = 7694

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6743 ILNTVLSQ 6750
>XP_005270753
          Length = 7700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6743 ILNTVLSQ 6750
>XP_006710583
          Length = 7702

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6722 ILNTVLSQ 6729
>XP_005270752
          Length = 7717

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6743 ILNTVLSQ 6750
>XP_006710582
          Length = 7720

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6740 ILNTVLSQ 6747
>XP_005270751
          Length = 7723

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    IANTILSQ 9
            I NT+LSQ
Sbjct: 6743 ILNTVLSQ 6750
>NP_004221
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  IANTILS 8
          +ANT+LS
Sbjct: 87 VANTLLS 93
>XP_006722999
          Length = 353

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  IANTILS 8
          +ANT+LS
Sbjct: 87 VANTLLS 93
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.314    0.120    0.276 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 251,975
Number of extensions: 321
Number of successful extensions: 34
Number of sequences better than 10000.0: 34
Number of HSP's gapped: 34
Number of HSP's successfully gapped: 34
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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