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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_000360                                                              19     869
XP_005268094                                                           19     869
NP_001274426                                                           18    1482
NP_071929                                                              18    1482
XP_005250584                                                           18    1482
NP_001012301                                                           17    2528
NP_115730                                                              17    3301
NP_898888                                                              17    3301
NP_004358                                                              17    4312
NP_113597                                                              17    4312
NP_001015891                                                           16    5631
NP_057367                                                              16    5631
NP_071351                                                              16    7355
NP_001050                                                              16    7355
NP_001829                                                              15    9605
NP_002634                                                              15    9605
NP_775097                                                              15    9605
NP_612382                                                              15    9605
NP_001018655                                                           15    9605
NP_001277117                                                           15    9605
NP_001277118                                                           15    9605
NP_001018656                                                           15    9605
NP_001277121                                                           15    9605
NP_001277120                                                           15    9605
NP_001277123                                                           15    9605
NP_001018657                                                           15    9605
NP_001277122                                                           15    9605
NP_001277119                                                           15    9605
NP_001018654                                                           15    9605
NP_004863                                                              15    9605
XP_005264426                                                           15    9605
XP_006711114                                                           15    9605
XP_005271408                                                           15    9605
XP_005271407                                                           15    9605
NP_112222                                                              15    9605

>NP_000360
          Length = 764

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AHIVFVLTL 9
           A+IVFVLTL
Sbjct: 581 AYIVFVLTL 589



>XP_005268094
          Length = 764

 Score = 18.9 bits (37), Expect =   869
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AHIVFVLTL 9
           A+IVFVLTL
Sbjct: 581 AYIVFVLTL 589



>NP_001274426
          Length = 697

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   HIVFVLTL 9
           HI+F+LTL
Sbjct: 309 HIIFLLTL 316



>NP_071929
          Length = 697

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   HIVFVLTL 9
           HI+F+LTL
Sbjct: 309 HIIFLLTL 316



>XP_005250584
          Length = 430

 Score = 18.1 bits (35), Expect =  1482
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   HIVFVLTL 9
           HI+F+LTL
Sbjct: 309 HIIFLLTL 316



>NP_001012301
          Length = 569

 Score = 17.3 bits (33), Expect =  2528
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  HIVFVLT 8
          HI+F+LT
Sbjct: 48 HIIFILT 54



>NP_115730
          Length = 146

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  AHIVFVLTL 9
          AH+V V+TL
Sbjct: 17 AHLVVVITL 25



>NP_898888
          Length = 140

 Score = 16.9 bits (32), Expect =  3301
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1  AHIVFVLTL 9
          AH+V V+TL
Sbjct: 17 AHLVVVITL 25



>NP_004358
          Length = 374

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AHIVFVLTL 9
          A I+FVLTL
Sbjct: 91 ADILFVLTL 99



>NP_113597
          Length = 374

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1  AHIVFVLTL 9
          A I+FVLTL
Sbjct: 91 ADILFVLTL 99



>NP_001015891
          Length = 169

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  HIVFVL 7
          HIVFVL
Sbjct: 87 HIVFVL 92



>NP_057367
          Length = 172

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  HIVFVL 7
          HIVFVL
Sbjct: 90 HIVFVL 95



>NP_071351
          Length = 2752

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  HIVFVLTL 9
          HI+F +TL
Sbjct: 74 HIIFHITL 81



>NP_001050
          Length = 465

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 2   HIVFVLT 8
           HI F+LT
Sbjct: 316 HIYFILT 322



>NP_001829
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 8/9 (88%)

Query: 1   AHIVFVLTL 9
           A I+F+LTL
Sbjct: 103 ADILFLLTL 111



>NP_002634
          Length = 219

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   HIVFVL 7
           H++FVL
Sbjct: 95  HVIFVL 100



>NP_775097
          Length = 206

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   HIVFVL 7
           H++FVL
Sbjct: 95  HVIFVL 100



>NP_612382
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AHIVFV 6
           AH+VFV
Sbjct: 315 AHLVFV 320



>NP_001018655
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AHIVFV 6
           AH+VFV
Sbjct: 315 AHLVFV 320



>NP_001277117
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AHIVFV 6
           AH+VFV
Sbjct: 315 AHLVFV 320



>NP_001277118
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AHIVFV 6
           AH+VFV
Sbjct: 315 AHLVFV 320



>NP_001018656
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AHIVFV 6
           AH+VFV
Sbjct: 315 AHLVFV 320



>NP_001277121
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AHIVFV 6
           AH+VFV
Sbjct: 315 AHLVFV 320



>NP_001277120
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AHIVFV 6
           AH+VFV
Sbjct: 315 AHLVFV 320



>NP_001277123
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AHIVFV 6
           AH+VFV
Sbjct: 315 AHLVFV 320



>NP_001018657
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AHIVFV 6
           AH+VFV
Sbjct: 315 AHLVFV 320



>NP_001277122
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AHIVFV 6
           AH+VFV
Sbjct: 315 AHLVFV 320



>NP_001277119
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AHIVFV 6
           AH+VFV
Sbjct: 315 AHLVFV 320



>NP_001018654
          Length = 322

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 1   AHIVFV 6
           AH+VFV
Sbjct: 315 AHLVFV 320



>NP_004863
          Length = 323

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   HIVFVLTL 9
           H++F LTL
Sbjct: 139 HLLFPLTL 146



>XP_005264426
          Length = 187

 Score = 15.4 bits (28), Expect =  9605
 Identities = 4/6 (66%), Positives = 6/6 (100%)

Query: 2   HIVFVL 7
           H++FVL
Sbjct: 95  HVIFVL 100



>XP_006711114
          Length = 256

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  HIVFVLTL 9
          H++F LTL
Sbjct: 72 HLLFPLTL 79



>XP_005271408
          Length = 257

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  HIVFVLTL 9
          H++F LTL
Sbjct: 72 HLLFPLTL 79



>XP_005271407
          Length = 324

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   HIVFVLTL 9
           H++F LTL
Sbjct: 139 HLLFPLTL 146



>NP_112222
          Length = 294

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AHIVFVLTL 9
           A ++FVLT+
Sbjct: 217 AALIFVLTI 225



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.350    0.154    0.446 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 441,568
Number of extensions: 618
Number of successful extensions: 35
Number of sequences better than 10000.0: 35
Number of HSP's gapped: 35
Number of HSP's successfully gapped: 35
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 14 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.9 bits)
S2: 28 (15.4 bits)