Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005148                                                              19     665
NP_009297                                                              19     665
NP_005392                                                              17    2528
NP_001269607                                                           16    5631
NP_001269606                                                           16    5631
NP_000457                                                              16    5631
NP_599031                                                              16    5631
NP_008863                                                              16    5631
NP_001193946                                                           16    5631
NP_599032                                                              16    5631
NP_061994                                                              16    5631
NP_079174                                                              16    5631
NP_001277260                                                           16    5631
NP_060482                                                              16    5631
NP_001157968                                                           16    5631
NP_005082                                                              16    5631
XP_006724370                                                           16    5631
XP_006724368                                                           16    5631
XP_006724367                                                           16    5631
XP_006724366                                                           16    5631
XP_006724364                                                           16    5631
XP_006724363                                                           16    5631
XP_006724362                                                           16    5631
XP_006724361                                                           16    5631
XP_006723222                                                           16    5631
XP_006722969                                                           16    5631
XP_006722968                                                           16    5631
XP_005259703                                                           16    5631
XP_005250490                                                           16    5631
XP_005250486                                                           16    5631
XP_005247674                                                           16    5631
XP_006713762                                                           16    5631
XP_006713761                                                           16    5631
XP_006713760                                                           16    5631
XP_006713759                                                           16    5631
NP_060808                                                              16    5631
NP_387450                                                              16    7355
NP_004352                                                              16    7355
NP_078925                                                              16    7355
NP_004925                                                              16    7355
NP_001034842                                                           16    7355
NP_006718                                                              16    7355
NP_006176                                                              16    7355
NP_001788                                                              16    7355
NP_001229797                                                           16    7355
NP_001273490                                                           16    7355
NP_057363                                                              16    7355
XP_005255821                                                           16    7355
XP_005255820                                                           16    7355
XP_005255819                                                           16    7355
XP_005255818                                                           16    7355
XP_006720777                                                           16    7355
XP_006719828                                                           16    7355
XP_006718633                                                           16    7355
XP_006718632                                                           16    7355
XP_006718631                                                           16    7355
XP_006718630                                                           16    7355
XP_006718629                                                           16    7355
XP_006718628                                                           16    7355
XP_006718627                                                           16    7355
XP_006718626                                                           16    7355
XP_006718625                                                           16    7355
XP_006714498                                                           16    7355
XP_005248285                                                           16    7355
XP_006712079                                                           16    7355
NP_659422                                                              16    7355
NP_071923                                                              16    7355
NP_056197                                                              15    9605
XP_005267560                                                           15    9605
XP_005267559                                                           15    9605
>NP_005148
          Length = 1130

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AGVSNGALR 9
           AGV NGALR
Sbjct: 666 AGVPNGALR 674
>NP_009297
          Length = 1149

 Score = 19.2 bits (38), Expect =   665
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AGVSNGALR 9
           AGV NGALR
Sbjct: 685 AGVPNGALR 693
>NP_005392
          Length = 1187

 Score = 17.3 bits (33), Expect =  2528
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 3   VSNGALR 9
           VSNGALR
Sbjct: 759 VSNGALR 765
>NP_001269607
          Length = 1075

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+ NGAL
Sbjct: 380 AGLRNGAL 387
>NP_001269606
          Length = 1226

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+ NGAL
Sbjct: 588 AGLRNGAL 595
>NP_000457
          Length = 1283

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+ NGAL
Sbjct: 588 AGLRNGAL 595
>NP_599031
          Length = 915

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AGVSNGALR 9
          AG+  GALR
Sbjct: 7  AGLDEGALR 15
>NP_008863
          Length = 917

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AGVSNGALR 9
          AG+  GALR
Sbjct: 7  AGLDEGALR 15
>NP_001193946
          Length = 1002

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AGVSNGALR 9
          AG+  GALR
Sbjct: 61 AGLDEGALR 69
>NP_599032
          Length = 940

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AGVSNGALR 9
          AG+  GALR
Sbjct: 7  AGLDEGALR 15
>NP_061994
          Length = 691

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGVSNGA 7
           AGV NGA
Sbjct: 490 AGVQNGA 496
>NP_079174
          Length = 801

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GVSNGALR 9
           G S+GALR
Sbjct: 413 GASSGALR 420
>NP_001277260
          Length = 757

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GVSNGALR 9
           G S+GALR
Sbjct: 369 GASSGALR 376
>NP_060482
          Length = 2108

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   GVSNGA 7
           GVSNGA
Sbjct: 272 GVSNGA 277
>NP_001157968
          Length = 1854

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GVSNGALR 9
           G+ NGA+R
Sbjct: 824 GMKNGAIR 831
>NP_005082
          Length = 196

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GVSNGALR 9
           GV+ GALR
Sbjct: 155 GVAQGALR 162
>XP_006724370
          Length = 646

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AGVSNGALR 9
          AG+  GALR
Sbjct: 7  AGLDEGALR 15
>XP_006724368
          Length = 677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AGVSNGALR 9
          AG+  GALR
Sbjct: 7  AGLDEGALR 15
>XP_006724367
          Length = 841

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AGVSNGALR 9
          AG+  GALR
Sbjct: 7  AGLDEGALR 15
>XP_006724366
          Length = 857

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AGVSNGALR 9
          AG+  GALR
Sbjct: 7  AGLDEGALR 15
>XP_006724364
          Length = 870

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AGVSNGALR 9
          AG+  GALR
Sbjct: 7  AGLDEGALR 15
>XP_006724363
          Length = 872

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AGVSNGALR 9
          AG+  GALR
Sbjct: 7  AGLDEGALR 15
>XP_006724362
          Length = 946

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AGVSNGALR 9
          AG+  GALR
Sbjct: 7  AGLDEGALR 15
>XP_006724361
          Length = 948

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AGVSNGALR 9
          AG+  GALR
Sbjct: 7  AGLDEGALR 15
>XP_006723222
          Length = 730

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 1   AGVSNGA 7
           AGV NGA
Sbjct: 490 AGVQNGA 496
>XP_006722969
          Length = 757

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GVSNGALR 9
           G S+GALR
Sbjct: 369 GASSGALR 376
>XP_006722968
          Length = 896

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GVSNGALR 9
           G S+GALR
Sbjct: 508 GASSGALR 515
>XP_005259703
          Length = 938

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2   GVSNGALR 9
           G S+GALR
Sbjct: 550 GASSGALR 557
>XP_005250490
          Length = 700

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1  AGVSNGAL 8
          AG+ NGAL
Sbjct: 5  AGLRNGAL 12
>XP_005250486
          Length = 1243

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+ NGAL
Sbjct: 548 AGLRNGAL 555
>XP_005247674
          Length = 1089

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2  GVSNGALR 9
          G+ NGA+R
Sbjct: 59 GMKNGAIR 66
>XP_006713762
          Length = 1197

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GVSNGALR 9
           G+ NGA+R
Sbjct: 868 GMKNGAIR 875
>XP_006713761
          Length = 1554

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GVSNGALR 9
           G+ NGA+R
Sbjct: 524 GMKNGAIR 531
>XP_006713760
          Length = 1847

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GVSNGALR 9
           G+ NGA+R
Sbjct: 817 GMKNGAIR 824
>XP_006713759
          Length = 1898

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GVSNGALR 9
           G+ NGA+R
Sbjct: 868 GMKNGAIR 875
>NP_060808
          Length = 982

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   GVSNGALR 9
           G+ NGA+R
Sbjct: 824 GMKNGAIR 831
>NP_387450
          Length = 785

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+S GAL
Sbjct: 603 AGLSTGAL 610
>NP_004352
          Length = 785

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+S GAL
Sbjct: 603 AGLSTGAL 610
>NP_078925
          Length = 593

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AGVSNGALR 9
           AG++NG +R
Sbjct: 348 AGLANGEVR 356
>NP_004925
          Length = 790

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+S GAL
Sbjct: 609 AGLSTGAL 616
>NP_001034842
          Length = 1958

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GVSNGAL 8
           GVSNG L
Sbjct: 597 GVSNGML 603
>NP_006718
          Length = 788

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+S GAL
Sbjct: 607 AGLSTGAL 614
>NP_006176
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AGVSNGA 7
            AGVS+GA
Sbjct: 1889 AGVSSGA 1895
>NP_001788
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+S GAL
Sbjct: 613 AGLSTGAL 620
>NP_001229797
          Length = 590

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  AGVSNGA 7
          AGVS+GA
Sbjct: 11 AGVSSGA 17
>NP_001273490
          Length = 2101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AGVSNGA 7
            AGVS+GA
Sbjct: 1875 AGVSSGA 1881
>NP_057363
          Length = 789

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+S GAL
Sbjct: 609 AGLSTGAL 616
>XP_005255821
          Length = 693

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+S GAL
Sbjct: 613 AGLSTGAL 620
>XP_005255820
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+S GAL
Sbjct: 613 AGLSTGAL 620
>XP_005255819
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+S GAL
Sbjct: 613 AGLSTGAL 620
>XP_005255818
          Length = 796

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+S GAL
Sbjct: 613 AGLSTGAL 620
>XP_006720777
          Length = 292

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2  GVSNGAL 8
          G+SNGA+
Sbjct: 29 GLSNGAM 35
>XP_006719828
          Length = 640

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1  AGVSNGA 7
          AGVS+GA
Sbjct: 11 AGVSSGA 17
>XP_006718633
          Length = 2101

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AGVSNGA 7
            AGVS+GA
Sbjct: 1875 AGVSSGA 1881
>XP_006718632
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AGVSNGA 7
            AGVS+GA
Sbjct: 1889 AGVSSGA 1895
>XP_006718631
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AGVSNGA 7
            AGVS+GA
Sbjct: 1889 AGVSSGA 1895
>XP_006718630
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AGVSNGA 7
            AGVS+GA
Sbjct: 1889 AGVSSGA 1895
>XP_006718629
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AGVSNGA 7
            AGVS+GA
Sbjct: 1889 AGVSSGA 1895
>XP_006718628
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AGVSNGA 7
            AGVS+GA
Sbjct: 1889 AGVSSGA 1895
>XP_006718627
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AGVSNGA 7
            AGVS+GA
Sbjct: 1889 AGVSSGA 1895
>XP_006718626
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AGVSNGA 7
            AGVS+GA
Sbjct: 1889 AGVSSGA 1895
>XP_006718625
          Length = 2115

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AGVSNGA 7
            AGVS+GA
Sbjct: 1889 AGVSSGA 1895
>XP_006714498
          Length = 790

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+S GAL
Sbjct: 609 AGLSTGAL 616
>XP_005248285
          Length = 790

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+S GAL
Sbjct: 609 AGLSTGAL 616
>XP_006712079
          Length = 1683

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 2   GVSNGAL 8
           GVSNG L
Sbjct: 355 GVSNGML 361
>NP_659422
          Length = 781

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+S GAL
Sbjct: 597 AGLSTGAL 604
>NP_071923
          Length = 819

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AGVSNGAL 8
           AG+S GAL
Sbjct: 635 AGLSTGAL 642
>NP_056197
          Length = 2610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VSNGALR 9
           VS+GALR
Sbjct: 202 VSDGALR 208
>XP_005267560
          Length = 2563

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VSNGALR 9
           VS+GALR
Sbjct: 202 VSDGALR 208
>XP_005267559
          Length = 2610

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   VSNGALR 9
           VS+GALR
Sbjct: 202 VSDGALR 208
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.311    0.128    0.345 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 522,477
Number of extensions: 1040
Number of successful extensions: 70
Number of sequences better than 10000.0: 70
Number of HSP's gapped: 70
Number of HSP's successfully gapped: 70
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.5 bits)
S2: 28 (15.4 bits)

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