Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1482
NP_001185763                                                           18    1482
NP_055459                                                              18    1482
XP_006726410                                                           18    1482
XP_006711719                                                           18    1482
XP_006711718                                                           18    1482
XP_006711717                                                           18    1482
XP_006711716                                                           18    1482
XP_006711715                                                           18    1482
XP_006711714                                                           18    1482
XP_006711713                                                           18    1482
XP_006711712                                                           18    1482
XP_006711711                                                           18    1482
XP_006711710                                                           18    1482
XP_006711709                                                           18    1482
XP_005277503                                                           18    1482
XP_005273038                                                           18    1482
XP_006711708                                                           18    1482
XP_005277500                                                           18    1482
XP_006711707                                                           18    1482
XP_005277499                                                           18    1482
XP_006711706                                                           18    1482
XP_006711705                                                           18    1482
XP_006711164                                                           18    1482
XP_006710143                                                           18    1482
XP_006710142                                                           18    1482
XP_006710141                                                           18    1482
XP_006725507                                                           16    5631
XP_003960032                                                           16    5631
NP_001185771                                                           16    7355
XP_005255567                                                           16    7355
XP_005255566                                                           16    7355
NP_006422                                                              16    7355
NP_078934                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1516 AGLEPLALR 1524
>NP_001185763
          Length = 2362

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1560 AGLEPLALR 1568
>NP_055459
          Length = 2346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1560 AGLEPLALR 1568
>XP_006726410
          Length = 2087

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1363 AGLEPLALR 1371
>XP_006711719
          Length = 2302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1516 AGLEPLALR 1524
>XP_006711718
          Length = 1436

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AGLEQLALR 9
           AGLE LALR
Sbjct: 567 AGLEPLALR 575
>XP_006711717
          Length = 2385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1516 AGLEPLALR 1524
>XP_006711716
          Length = 2411

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1625 AGLEPLALR 1633
>XP_006711715
          Length = 2428

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1559 AGLEPLALR 1567
>XP_006711714
          Length = 2429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1560 AGLEPLALR 1568
>XP_006711713
          Length = 2432

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1563 AGLEPLALR 1571
>XP_006711712
          Length = 2473

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1723 AGLEPLALR 1731
>XP_006711711
          Length = 2482

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1613 AGLEPLALR 1621
>XP_006711710
          Length = 2494

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1625 AGLEPLALR 1633
>XP_006711709
          Length = 2495

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1626 AGLEPLALR 1634
>XP_005277503
          Length = 2498

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1723 AGLEPLALR 1731
>XP_005273038
          Length = 2509

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1723 AGLEPLALR 1731
>XP_006711708
          Length = 2512

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1723 AGLEPLALR 1731
>XP_005277500
          Length = 2525

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1723 AGLEPLALR 1731
>XP_006711707
          Length = 2553

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1723 AGLEPLALR 1731
>XP_005277499
          Length = 2561

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1723 AGLEPLALR 1731
>XP_006711706
          Length = 2591

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1722 AGLEPLALR 1730
>XP_006711705
          Length = 2592

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1723 AGLEPLALR 1731
>XP_006711164
          Length = 2087

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AGLEQLALR 9
            AGLE LALR
Sbjct: 1363 AGLEPLALR 1371
>XP_006710143
          Length = 562

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AGLEQLALR 9
           AGLE LALR
Sbjct: 402 AGLEPLALR 410
>XP_006710142
          Length = 671

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AGLEQLALR 9
           AGLE LALR
Sbjct: 511 AGLEPLALR 519
>XP_006710141
          Length = 672

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AGLEQLALR 9
           AGLE LALR
Sbjct: 512 AGLEPLALR 520
>XP_006725507
          Length = 337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  GLEQLALR 9
          GL+Q+A+R
Sbjct: 3  GLDQMAIR 10
>XP_003960032
          Length = 337

 Score = 16.2 bits (30), Expect =  5631
 Identities = 5/8 (62%), Positives = 8/8 (100%)

Query: 2  GLEQLALR 9
          GL+Q+A+R
Sbjct: 3  GLDQMAIR 10
>NP_001185771
          Length = 488

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AGLEQLAL 8
           AG+E+LAL
Sbjct: 271 AGVERLAL 278
>XP_005255567
          Length = 330

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AGLEQLA 7
           AGLEQL+
Sbjct: 152 AGLEQLS 158
>XP_005255566
          Length = 331

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AGLEQLA 7
           AGLEQL+
Sbjct: 153 AGLEQLS 159
>NP_006422
          Length = 535

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AGLEQLAL 8
           AG+E+LAL
Sbjct: 318 AGVERLAL 325
>NP_078934
          Length = 1081

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 1 AGLEQL 6
         AGLEQL
Sbjct: 4 AGLEQL 9
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.321    0.138    0.346 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 443,893
Number of extensions: 539
Number of successful extensions: 34
Number of sequences better than 10000.0: 34
Number of HSP's gapped: 34
Number of HSP's successfully gapped: 34
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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