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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005742                                                              18    1482
NP_671714                                                              18    1482
NP_149037                                                              18    1482
NP_001171700                                                           18    1482
XP_006715890                                                           18    1482
XP_005250160                                                           18    1482
XP_005250159                                                           18    1482
NP_054733                                                              18    1935
NP_055826                                                              16    7355
NP_001185879                                                           16    7355
NP_569120                                                              15    9605
NP_569122                                                              15    9605
NP_001387                                                              15    9605
NP_567824                                                              15    9605
NP_006475                                                              15    9605
NP_004705                                                              15    9605
NP_001034864                                                           15    9605
NP_006474                                                              15    9605
XP_005260988                                                           15    9605
XP_006724042                                                           15    9605
XP_006724041                                                           15    9605
XP_006724040                                                           15    9605
XP_006724039                                                           15    9605
XP_005259455                                                           15    9605
XP_006723528                                                           15    9605
XP_006723527                                                           15    9605
XP_005259452                                                           15    9605
XP_005245975                                                           15    9605

>NP_005742
          Length = 3907

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AFVSQIQLE 9
            A VSQIQLE
Sbjct: 2554 ALVSQIQLE 2562



>NP_671714
          Length = 3899

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AFVSQIQLE 9
            A VSQIQLE
Sbjct: 2546 ALVSQIQLE 2554



>NP_149037
          Length = 301

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   FVSQIQLE 9
           FVSQIQ+E
Sbjct: 238 FVSQIQIE 245



>NP_001171700
          Length = 301

 Score = 18.1 bits (35), Expect =  1482
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 2   FVSQIQLE 9
           FVSQIQ+E
Sbjct: 238 FVSQIQIE 245



>XP_006715890
          Length = 3860

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AFVSQIQLE 9
            A VSQIQLE
Sbjct: 2507 ALVSQIQLE 2515



>XP_005250160
          Length = 3939

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AFVSQIQLE 9
            A VSQIQLE
Sbjct: 2586 ALVSQIQLE 2594



>XP_005250159
          Length = 3952

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1    AFVSQIQLE 9
            A VSQIQLE
Sbjct: 2599 ALVSQIQLE 2607



>NP_054733
          Length = 2136

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1    AFVSQIQLE 9
            AF+SQ++LE
Sbjct: 1065 AFISQLKLE 1073



>NP_055826
          Length = 1858

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AFVSQIQL 8
           AFVS +QL
Sbjct: 686 AFVSDLQL 693



>NP_001185879
          Length = 1880

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AFVSQIQL 8
           AFVS +QL
Sbjct: 708 AFVSDLQL 715



>NP_569120
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 186 AFLNQAQIE 194



>NP_569122
          Length = 529

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 195 AFLNQAQIE 203



>NP_001387
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 195 AFLNQAQIE 203



>NP_567824
          Length = 584

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 195 AFLNQAQIE 203



>NP_006475
          Length = 601

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 147 AFLNQAQIE 155



>NP_004705
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 147 AFLNQAQIE 155



>NP_001034864
          Length = 1661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    FVSQIQL 8
            FVS+IQL
Sbjct: 1354 FVSKIQL 1360



>NP_006474
          Length = 589

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 147 AFLNQAQIE 155



>XP_005260988
          Length = 734

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 166 AFLNQAQIE 174



>XP_006724042
          Length = 754

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 186 AFLNQAQIE 194



>XP_006724041
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 195 AFLNQAQIE 203



>XP_006724040
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 195 AFLNQAQIE 203



>XP_006724039
          Length = 763

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 195 AFLNQAQIE 203



>XP_005259455
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 147 AFLNQAQIE 155



>XP_006723528
          Length = 649

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 207 AFLNQAQIE 215



>XP_006723527
          Length = 661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 207 AFLNQAQIE 215



>XP_005259452
          Length = 689

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AFVSQIQLE 9
           AF++Q Q+E
Sbjct: 207 AFLNQAQIE 215



>XP_005245975
          Length = 1661

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    FVSQIQL 8
            FVS+IQL
Sbjct: 1354 FVSKIQL 1360



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.325    0.133    0.317 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 329,517
Number of extensions: 406
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.0 bits)
S2: 28 (15.4 bits)