Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_005350                                                              18    1482
NP_076427                                                              17    3301
NP_001077393                                                           17    3301
XP_005273316                                                           17    3301
XP_006711593                                                           17    3301
NP_006288                                                              16    5631
NP_003165                                                              16    7355
XP_006717559                                                           16    7355
XP_006717558                                                           16    7355
XP_005252626                                                           16    7355
XP_005252623                                                           16    7355
NP_001001412                                                           15    9605
NP_009117                                                              15    9605
NP_055474                                                              15    9605
NP_001124331                                                           15    9605
NP_001124330                                                           15    9605
NP_001177143                                                           15    9605
XP_005260322                                                           15    9605
XP_005260321                                                           15    9605
XP_005260320                                                           15    9605
XP_006723758                                                           15    9605
XP_006723757                                                           15    9605
XP_006723756                                                           15    9605
XP_006723755                                                           15    9605
XP_006723754                                                           15    9605
XP_006723753                                                           15    9605
XP_005260319                                                           15    9605
XP_006720850                                                           15    9605
XP_006720849                                                           15    9605
XP_005254861                                                           15    9605
XP_006720848                                                           15    9605
XP_005254860                                                           15    9605
XP_006720847                                                           15    9605
XP_006720846                                                           15    9605
XP_005254859                                                           15    9605
XP_006720845                                                           15    9605
XP_005254858                                                           15    9605
>NP_005350
          Length = 552

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AATAQASAA 9
           AATAQA+AA
Sbjct: 451 AATAQAAAA 459
>NP_076427
          Length = 601

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AATAQASAA 9
           AA AQASAA
Sbjct: 394 AAPAQASAA 402
>NP_001077393
          Length = 355

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AATAQASAA 9
           AA AQASAA
Sbjct: 148 AAPAQASAA 156
>XP_005273316
          Length = 355

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AATAQASAA 9
           AA AQASAA
Sbjct: 148 AAPAQASAA 156
>XP_006711593
          Length = 601

 Score = 16.9 bits (32), Expect =  3301
 Identities = 8/9 (88%), Positives = 8/9 (88%)

Query: 1   AATAQASAA 9
           AA AQASAA
Sbjct: 394 AAPAQASAA 402
>NP_006288
          Length = 633

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AATAQASAA 9
           AAT QAS+A
Sbjct: 213 AATLQASSA 221
>NP_003165
          Length = 1788

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AATAQASA 8
           AAT QASA
Sbjct: 353 AATLQASA 360
>XP_006717559
          Length = 1866

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AATAQASA 8
           AAT QASA
Sbjct: 431 AATLQASA 438
>XP_006717558
          Length = 1908

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AATAQASA 8
           AAT QASA
Sbjct: 431 AATLQASA 438
>XP_005252626
          Length = 2260

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AATAQASA 8
           AAT QASA
Sbjct: 825 AATLQASA 832
>XP_005252623
          Length = 2302

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AATAQASA 8
           AAT QASA
Sbjct: 825 AATLQASA 832
>NP_001001412
          Length = 346

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATAQASAA 9
           ATA ASAA
Sbjct: 268 ATAPASAA 275
>NP_009117
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1367 ARAQASAA 1374
>NP_055474
          Length = 1408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1097 AQAQASAA 1104
>NP_001124331
          Length = 1408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1097 AQAQASAA 1104
>NP_001124330
          Length = 1433

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1122 AQAQASAA 1129
>NP_001177143
          Length = 1406

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1055 AQAQASAA 1062
>XP_005260322
          Length = 1810

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2   ATAQASAA 9
           A AQASAA
Sbjct: 735 ARAQASAA 742
>XP_005260321
          Length = 2365

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1290 ARAQASAA 1297
>XP_005260320
          Length = 2370

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1367 ARAQASAA 1374
>XP_006723758
          Length = 2386

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1311 ARAQASAA 1318
>XP_006723757
          Length = 2404

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1367 ARAQASAA 1374
>XP_006723756
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1367 ARAQASAA 1374
>XP_006723755
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1367 ARAQASAA 1374
>XP_006723754
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1367 ARAQASAA 1374
>XP_006723753
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1367 ARAQASAA 1374
>XP_005260319
          Length = 2442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1367 ARAQASAA 1374
>XP_006720850
          Length = 1421

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1110 AQAQASAA 1117
>XP_006720849
          Length = 1366

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1055 AQAQASAA 1062
>XP_005254861
          Length = 1408

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1097 AQAQASAA 1104
>XP_006720848
          Length = 1427

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1116 AQAQASAA 1123
>XP_005254860
          Length = 1429

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1118 AQAQASAA 1125
>XP_006720847
          Length = 1461

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1150 AQAQASAA 1157
>XP_006720846
          Length = 1469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1158 AQAQASAA 1165
>XP_005254859
          Length = 1469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1158 AQAQASAA 1165
>XP_006720845
          Length = 1469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1158 AQAQASAA 1165
>XP_005254858
          Length = 1469

 Score = 15.4 bits (28), Expect =  9605
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 2    ATAQASAA 9
            A AQASAA
Sbjct: 1158 AQAQASAA 1165
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.286   0.0805    0.165 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 132,202
Number of extensions: 246
Number of successful extensions: 37
Number of sequences better than 10000.0: 37
Number of HSP's gapped: 37
Number of HSP's successfully gapped: 37
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 17 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.2 bits)
S2: 28 (15.4 bits)

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