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Blast-Search of mutated query peptide against human proteome

BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_945352                                                              18    1935
XP_005266141                                                           18    1935
NP_001129941                                                           17    3301
NP_076432                                                              17    3301
XP_005247785                                                           17    3301
XP_005247784                                                           17    3301
XP_005247783                                                           17    3301
XP_005247782                                                           17    3301
NP_116207                                                              16    5631
NP_848638                                                              16    7355
NP_001263347                                                           16    7355
NP_055681                                                              16    7355
NP_055633                                                              16    7355
XP_005277842                                                           16    7355
XP_006718461                                                           16    7355
XP_006718460                                                           16    7355
XP_005266194                                                           16    7355
XP_005266193                                                           16    7355
XP_005266191                                                           16    7355
XP_005266190                                                           16    7355
XP_005266189                                                           16    7355
NP_006139                                                              15    9605
NP_001258537                                                           15    9605
NP_004090                                                              15    9605
XP_005276376                                                           15    9605
XP_005272546                                                           15    9605
XP_006722863                                                           15    9605
XP_006719973                                                           15    9605
XP_005251388                                                           15    9605
XP_005276077                                                           15    9605

>NP_945352
          Length = 184

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   AAPVQSQRA 9
           AAP+Q+Q+A
Sbjct: 115 AAPIQNQQA 123



>XP_005266141
          Length = 184

 Score = 17.7 bits (34), Expect =  1935
 Identities = 6/9 (66%), Positives = 9/9 (100%)

Query: 1   AAPVQSQRA 9
           AAP+Q+Q+A
Sbjct: 115 AAPIQNQQA 123



>NP_001129941
          Length = 575

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAPVQSQR 8
           AAPV SQR
Sbjct: 312 AAPVPSQR 319



>NP_076432
          Length = 575

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAPVQSQR 8
           AAPV SQR
Sbjct: 312 AAPVPSQR 319



>XP_005247785
          Length = 488

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAPVQSQR 8
           AAPV SQR
Sbjct: 312 AAPVPSQR 319



>XP_005247784
          Length = 569

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAPVQSQR 8
           AAPV SQR
Sbjct: 306 AAPVPSQR 313



>XP_005247783
          Length = 575

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAPVQSQR 8
           AAPV SQR
Sbjct: 312 AAPVPSQR 319



>XP_005247782
          Length = 575

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1   AAPVQSQR 8
           AAPV SQR
Sbjct: 312 AAPVPSQR 319



>NP_116207
          Length = 335

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3  PVQSQRA 9
          PVQ QRA
Sbjct: 11 PVQEQRA 17



>NP_848638
          Length = 458

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2  APVQSQ 7
          APVQSQ
Sbjct: 22 APVQSQ 27



>NP_001263347
          Length = 2334

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AAPVQSQ 7
           AAPVQS+
Sbjct: 776 AAPVQSR 782



>NP_055681
          Length = 2357

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AAPVQSQ 7
           AAPVQS+
Sbjct: 776 AAPVQSR 782



>NP_055633
          Length = 1216

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   APVQSQ 7
           APVQSQ
Sbjct: 559 APVQSQ 564



>XP_005277842
          Length = 468

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   APVQSQ 7
           APVQSQ
Sbjct: 95  APVQSQ 100



>XP_006718461
          Length = 1247

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   APVQSQ 7
           APVQSQ
Sbjct: 559 APVQSQ 564



>XP_006718460
          Length = 1392

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 2   APVQSQ 7
           APVQSQ
Sbjct: 704 APVQSQ 709



>XP_005266194
          Length = 2379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AAPVQSQ 7
           AAPVQS+
Sbjct: 776 AAPVQSR 782



>XP_005266193
          Length = 2248

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AAPVQSQ 7
           AAPVQS+
Sbjct: 924 AAPVQSR 930



>XP_005266191
          Length = 2379

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AAPVQSQ 7
           AAPVQS+
Sbjct: 776 AAPVQSR 782



>XP_005266190
          Length = 2485

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AAPVQSQ 7
           AAPVQS+
Sbjct: 924 AAPVQSR 930



>XP_005266189
          Length = 2505

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AAPVQSQ 7
           AAPVQS+
Sbjct: 924 AAPVQSR 930



>NP_006139
          Length = 261

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AAPVQSQRA 9
           AAPV  QR+
Sbjct: 190 AAPVSIQRS 198



>NP_001258537
          Length = 205

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AAPVQSQRA 9
           AAPV  QR+
Sbjct: 134 AAPVSIQRS 142



>NP_004090
          Length = 288

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 6/7 (85%)

Query: 3   PVQSQRA 9
           PVQ QRA
Sbjct: 200 PVQLQRA 206



>XP_005276376
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AAPVQSQRA 9
           +AP+Q+Q A
Sbjct: 147 SAPLQAQEA 155



>XP_005272546
          Length = 435

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  APVQSQRA 9
          AP  SQRA
Sbjct: 50 APAPSQRA 57



>XP_006722863
          Length = 442

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2  APVQSQRA 9
          AP  SQRA
Sbjct: 50 APAPSQRA 57



>XP_006719973
          Length = 287

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AAPVQSQRA 9
           +AP+QS +A
Sbjct: 188 SAPIQSAQA 196



>XP_005251388
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AAPVQSQRA 9
           +AP+Q+Q A
Sbjct: 147 SAPLQAQEA 155



>XP_005276077
          Length = 200

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/9 (55%), Positives = 8/9 (88%)

Query: 1   AAPVQSQRA 9
           +AP+Q+Q A
Sbjct: 147 SAPLQAQEA 155



  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.307    0.108    0.272 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 571,784
Number of extensions: 1020
Number of successful extensions: 30
Number of sequences better than 10000.0: 30
Number of HSP's gapped: 30
Number of HSP's successfully gapped: 30
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.6 bits)
S2: 28 (15.4 bits)