Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001185761                                                           18    1482
NP_001185763                                                           18    1482
NP_055459                                                              18    1482
NP_001002811                                                           18    1482
NP_001002812                                                           18    1482
XP_006726410                                                           18    1482
XP_006711719                                                           18    1482
XP_006711717                                                           18    1482
XP_006711716                                                           18    1482
XP_006711715                                                           18    1482
XP_006711714                                                           18    1482
XP_006711713                                                           18    1482
XP_006711712                                                           18    1482
XP_006711711                                                           18    1482
XP_006711710                                                           18    1482
XP_006711709                                                           18    1482
XP_005277503                                                           18    1482
XP_005273038                                                           18    1482
XP_006711708                                                           18    1482
XP_005277500                                                           18    1482
XP_006711707                                                           18    1482
XP_005277499                                                           18    1482
XP_006711706                                                           18    1482
XP_006711705                                                           18    1482
XP_006711164                                                           18    1482
XP_006710144                                                           18    1482
NP_203752                                                              16    5631
NP_003743                                                              16    5631
NP_001254503                                                           16    5631
NP_001273407                                                           16    5631
NP_001032897                                                           16    5631
NP_001186071                                                           16    5631
NP_001093131                                                           16    5631
XP_005255592                                                           16    5631
XP_006715629                                                           16    5631
XP_006712877                                                           16    5631
XP_006712876                                                           16    5631
XP_006712875                                                           16    5631
XP_006712874                                                           16    5631
XP_006712873                                                           16    5631
XP_006712872                                                           16    5631
XP_005246976                                                           16    5631
XP_005246975                                                           16    5631
NP_078970                                                              16    5631
NP_000548                                                              15    9605
XP_005246847                                                           15    9605
XP_006712769                                                           15    9605
XP_006712768                                                           15    9605
XP_006712767                                                           15    9605
XP_006712766                                                           15    9605
XP_005246846                                                           15    9605
NP_005061                                                              15    9605
NP_963868                                                              15    9605
>NP_001185761
          Length = 2240

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 406 ALLDLQSA 413
>NP_001185763
          Length = 2362

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 340 ALLDLQSA 347
>NP_055459
          Length = 2346

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 340 ALLDLQSA 347
>NP_001002811
          Length = 1132

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 503 ALLDLQSA 510
>NP_001002812
          Length = 969

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 340 ALLDLQSA 347
>XP_006726410
          Length = 2087

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 415 ALLDLQSA 422
>XP_006711719
          Length = 2302

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 406 ALLDLQSA 413
>XP_006711717
          Length = 2385

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 406 ALLDLQSA 413
>XP_006711716
          Length = 2411

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 406 ALLDLQSA 413
>XP_006711715
          Length = 2428

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 340 ALLDLQSA 347
>XP_006711714
          Length = 2429

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 340 ALLDLQSA 347
>XP_006711713
          Length = 2432

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 343 ALLDLQSA 350
>XP_006711712
          Length = 2473

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 503 ALLDLQSA 510
>XP_006711711
          Length = 2482

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 503 ALLDLQSA 510
>XP_006711710
          Length = 2494

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 406 ALLDLQSA 413
>XP_006711709
          Length = 2495

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 406 ALLDLQSA 413
>XP_005277503
          Length = 2498

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 503 ALLDLQSA 510
>XP_005273038
          Length = 2509

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 503 ALLDLQSA 510
>XP_006711708
          Length = 2512

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 503 ALLDLQSA 510
>XP_005277500
          Length = 2525

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 503 ALLDLQSA 510
>XP_006711707
          Length = 2553

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 503 ALLDLQSA 510
>XP_005277499
          Length = 2561

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 503 ALLDLQSA 510
>XP_006711706
          Length = 2591

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 503 ALLDLQSA 510
>XP_006711705
          Length = 2592

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 503 ALLDLQSA 510
>XP_006711164
          Length = 2087

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 415 ALLDLQSA 422
>XP_006710144
          Length = 564

 Score = 18.1 bits (35), Expect =  1482
 Identities = 8/8 (100%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLDLQSA
Sbjct: 503 ALLDLQSA 510
>NP_203752
          Length = 1861

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AALLDLQSA 9
            AAL DLQ A
Sbjct: 1388 AALADLQEA 1396
>NP_003743
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLD+QS+
Sbjct: 632 ALLDIQSS 639
>NP_001254503
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLD+QS+
Sbjct: 632 ALLDIQSS 639
>NP_001273407
          Length = 903

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLD+QS+
Sbjct: 622 ALLDIQSS 629
>NP_001032897
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLD+QS+
Sbjct: 632 ALLDIQSS 639
>NP_001186071
          Length = 913

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLD+QS+
Sbjct: 632 ALLDIQSS 639
>NP_001093131
          Length = 914

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLD+QS+
Sbjct: 633 ALLDIQSS 640
>XP_005255592
          Length = 914

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 2   ALLDLQSA 9
           ALLD+QS+
Sbjct: 633 ALLDIQSS 640
>XP_006715629
          Length = 1667

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AALLDLQSA 9
           AAL DLQ+A
Sbjct: 815 AALKDLQTA 823
>XP_006712877
          Length = 1677

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AALLDLQSA 9
            AAL DLQ A
Sbjct: 1204 AALADLQEA 1212
>XP_006712876
          Length = 1783

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AALLDLQSA 9
            AAL DLQ A
Sbjct: 1310 AALADLQEA 1318
>XP_006712875
          Length = 1826

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AALLDLQSA 9
            AAL DLQ A
Sbjct: 1353 AALADLQEA 1361
>XP_006712874
          Length = 1836

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AALLDLQSA 9
            AAL DLQ A
Sbjct: 1363 AALADLQEA 1371
>XP_006712873
          Length = 1861

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AALLDLQSA 9
            AAL DLQ A
Sbjct: 1388 AALADLQEA 1396
>XP_006712872
          Length = 1861

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AALLDLQSA 9
            AAL DLQ A
Sbjct: 1388 AALADLQEA 1396
>XP_005246976
          Length = 1864

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AALLDLQSA 9
            AAL DLQ A
Sbjct: 1391 AALADLQEA 1399
>XP_005246975
          Length = 1871

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 7/9 (77%)

Query: 1    AALLDLQSA 9
            AAL DLQ A
Sbjct: 1398 AALADLQEA 1406
>NP_078970
          Length = 1667

 Score = 16.2 bits (30), Expect =  5631
 Identities = 7/9 (77%), Positives = 8/9 (88%)

Query: 1   AALLDLQSA 9
           AAL DLQ+A
Sbjct: 815 AALKDLQTA 823
>NP_000548
          Length = 501

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 8/8 (100%)

Query: 1   AALLDLQS 8
           AALLD++S
Sbjct: 275 AALLDVRS 282
>XP_005246847
          Length = 1034

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AALLDLQ 7
           AALLDL+
Sbjct: 184 AALLDLE 190
>XP_006712769
          Length = 1059

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AALLDLQ 7
           AALLDL+
Sbjct: 209 AALLDLE 215
>XP_006712768
          Length = 1150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AALLDLQ 7
           AALLDL+
Sbjct: 300 AALLDLE 306
>XP_006712767
          Length = 1150

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AALLDLQ 7
           AALLDL+
Sbjct: 300 AALLDLE 306
>XP_006712766
          Length = 1179

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AALLDLQ 7
           AALLDL+
Sbjct: 329 AALLDLE 335
>XP_005246846
          Length = 1259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AALLDLQ 7
           AALLDL+
Sbjct: 409 AALLDLE 415
>NP_005061
          Length = 1232

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AALLDLQ 7
           AALLDL+
Sbjct: 382 AALLDLE 388
>NP_963868
          Length = 1259

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AALLDLQ 7
           AALLDL+
Sbjct: 409 AALLDLE 415
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.315    0.123    0.283 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 362,167
Number of extensions: 264
Number of successful extensions: 53
Number of sequences better than 10000.0: 53
Number of HSP's gapped: 53
Number of HSP's successfully gapped: 53
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.8 bits)
S2: 28 (15.4 bits)

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