Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_004295                                                              20     390
NP_001909                                                              18    1935
XP_005270603                                                           18    1935
XP_005270602                                                           18    1935
NP_001252541                                                           17    4312
NP_057368                                                              17    4312
NP_940931                                                              17    4312
XP_006721943                                                           17    4312
XP_006721942                                                           17    4312
NP_476506                                                              16    5631
NP_476505                                                              16    5631
NP_004360                                                              16    5631
NP_476508                                                              16    5631
NP_476507                                                              16    5631
XP_005246123                                                           16    5631
XP_005246122                                                           16    5631
XP_006712316                                                           16    5631
NP_115514                                                              16    5631
NP_690867                                                              16    5631
NP_001185797                                                           16    7355
NP_005177                                                              16    7355
NP_001185798                                                           16    7355
NP_000688                                                              16    7355
NP_003777                                                              16    7355
NP_057595                                                              16    7355
NP_114416                                                              16    7355
NP_001166245                                                           16    7355
XP_006723108                                                           16    7355
XP_005258618                                                           16    7355
XP_005257820                                                           16    7355
XP_006718761                                                           16    7355
NP_997208                                                              16    7355
NP_006421                                                              15    9605
NP_001243650                                                           15    9605
NP_861441                                                              15    9605
NP_006057                                                              15    9605
NP_697021                                                              15    9605
NP_001189342                                                           15    9605
NP_001189343                                                           15    9605
NP_001239200                                                           15    9605
NP_001006606                                                           15    9605
NP_689634                                                              15    9605
NP_001239199                                                           15    9605
NP_001239198                                                           15    9605
XP_006717017                                                           15    9605
XP_005268434                                                           15    9605
XP_006714819                                                           15    9605
>NP_004295
          Length = 1620

 Score = 20.0 bits (40), Expect =   390
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AALGLLQFN 9
           AA+GLLQFN
Sbjct: 161 AAVGLLQFN 169
>NP_001909
          Length = 482

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AALGLLQF 8
           A+LGLLQF
Sbjct: 315 ASLGLLQF 322
>XP_005270603
          Length = 301

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AALGLLQF 8
           A+LGLLQF
Sbjct: 134 ASLGLLQF 141
>XP_005270602
          Length = 301

 Score = 17.7 bits (34), Expect =  1935
 Identities = 7/8 (87%), Positives = 8/8 (100%)

Query: 1   AALGLLQF 8
           A+LGLLQF
Sbjct: 134 ASLGLLQF 141
>NP_001252541
          Length = 2371

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    AALGLLQ 7
            AALGLLQ
Sbjct: 1652 AALGLLQ 1658
>NP_057368
          Length = 2376

 Score = 16.5 bits (31), Expect =  4312
 Identities = 7/7 (100%), Positives = 7/7 (100%)

Query: 1    AALGLLQ 7
            AALGLLQ
Sbjct: 1657 AALGLLQ 1663
>NP_940931
          Length = 1503

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ALGLLQFN 9
            ALG+L FN
Sbjct: 1262 ALGVLDFN 1269
>XP_006721943
          Length = 1456

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ALGLLQFN 9
            ALG+L FN
Sbjct: 1262 ALGVLDFN 1269
>XP_006721942
          Length = 1503

 Score = 16.5 bits (31), Expect =  4312
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 2    ALGLLQFN 9
            ALG+L FN
Sbjct: 1262 ALGVLDFN 1269
>NP_476506
          Length = 1237

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AALGLLQFN 9
           +ALGL  FN
Sbjct: 248 SALGLANFN 256
>NP_476505
          Length = 1036

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AALGLLQFN 9
          +ALGL  FN
Sbjct: 47 SALGLANFN 55
>NP_004360
          Length = 3177

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AALGLLQFN 9
           +ALGL  FN
Sbjct: 454 SALGLANFN 462
>NP_476508
          Length = 2971

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AALGLLQFN 9
           +ALGL  FN
Sbjct: 248 SALGLANFN 256
>NP_476507
          Length = 2570

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AALGLLQFN 9
          +ALGL  FN
Sbjct: 47 SALGLANFN 55
>XP_005246123
          Length = 2770

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1  AALGLLQFN 9
          +ALGL  FN
Sbjct: 47 SALGLANFN 55
>XP_005246122
          Length = 2977

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AALGLLQFN 9
           +ALGL  FN
Sbjct: 454 SALGLANFN 462
>XP_006712316
          Length = 3010

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/9 (66%), Positives = 7/9 (77%)

Query: 1   AALGLLQFN 9
           +ALGL  FN
Sbjct: 454 SALGLANFN 462
>NP_115514
          Length = 684

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LGLLQFN 9
           LGLLQF+
Sbjct: 602 LGLLQFD 608
>NP_690867
          Length = 674

 Score = 16.2 bits (30), Expect =  5631
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 3   LGLLQFN 9
           LGLLQF+
Sbjct: 602 LGLLQFD 608
>NP_001185797
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LGLLQFN 9
           LGL++FN
Sbjct: 605 LGLVEFN 611
>NP_005177
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LGLLQFN 9
           LGL++FN
Sbjct: 605 LGLVEFN 611
>NP_001185798
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LGLLQFN 9
           LGL++FN
Sbjct: 605 LGLVEFN 611
>NP_000688
          Length = 663

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/6 (100%), Positives = 6/6 (100%)

Query: 3  LGLLQF 8
          LGLLQF
Sbjct: 57 LGLLQF 62
>NP_003777
          Length = 1527

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1    AALGLLQ 7
            AALG+LQ
Sbjct: 1016 AALGILQ 1022
>NP_057595
          Length = 280

 Score = 15.8 bits (29), Expect =  7355
 Identities = 7/8 (87%), Positives = 7/8 (87%)

Query: 1  AALGLLQF 8
          AALGLL F
Sbjct: 66 AALGLLFF 73
>NP_114416
          Length = 207

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2   ALGLLQF 8
           ALGLL+F
Sbjct: 145 ALGLLKF 151
>NP_001166245
          Length = 716

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ALGLLQFN 9
           A GLL FN
Sbjct: 400 AFGLLPFN 407
>XP_006723108
          Length = 520

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ALGLLQFN 9
           A GLL FN
Sbjct: 204 AFGLLPFN 211
>XP_005258618
          Length = 682

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ALGLLQFN 9
           A GLL FN
Sbjct: 366 AFGLLPFN 373
>XP_005257820
          Length = 1463

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 1   AALGLLQ 7
           AALG+LQ
Sbjct: 952 AALGILQ 958
>XP_006718761
          Length = 714

 Score = 15.8 bits (29), Expect =  7355
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 3   LGLLQFN 9
           LGL++FN
Sbjct: 605 LGLVEFN 611
>NP_997208
          Length = 716

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ALGLLQFN 9
           A GLL FN
Sbjct: 400 AFGLLPFN 407
>NP_006421
          Length = 539

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AALGLLQF 8
           A +GL+QF
Sbjct: 244 AKIGLIQF 251
>NP_001243650
          Length = 509

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 1   AALGLLQF 8
           A +GL+QF
Sbjct: 214 AKIGLIQF 221
>NP_861441
          Length = 483

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AALGLLQF 8
           AALG L+F
Sbjct: 314 AALGYLRF 321
>NP_006057
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ALGLLQFN 9
           ALGL  FN
Sbjct: 158 ALGLSNFN 165
>NP_697021
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ALGLLQFN 9
           ALGL  FN
Sbjct: 158 ALGLSNFN 165
>NP_001189342
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ALGLLQFN 9
           ALGL  FN
Sbjct: 158 ALGLSNFN 165
>NP_001189343
          Length = 325

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 6/8 (75%)

Query: 2   ALGLLQFN 9
           ALGL  FN
Sbjct: 158 ALGLSNFN 165
>NP_001239200
          Length = 403

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ALGLLQF 8
           A+GLL+F
Sbjct: 247 AIGLLEF 253
>NP_001006606
          Length = 428

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ALGLLQF 8
           A+GLL+F
Sbjct: 272 AIGLLEF 278
>NP_689634
          Length = 431

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ALGLLQF 8
           A+GLL+F
Sbjct: 275 AIGLLEF 281
>NP_001239199
          Length = 369

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ALGLLQF 8
           A+GLL+F
Sbjct: 213 AIGLLEF 219
>NP_001239198
          Length = 383

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ALGLLQF 8
           A+GLL+F
Sbjct: 227 AIGLLEF 233
>XP_006717017
          Length = 434

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   ALGLLQF 8
           A+GLL+F
Sbjct: 278 AIGLLEF 284
>XP_005268434
          Length = 393

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AALGLLQF 8
           AALG L+F
Sbjct: 314 AALGYLRF 321
>XP_006714819
          Length = 450

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/8 (75%), Positives = 7/8 (87%)

Query: 1   AALGLLQF 8
           AALG L+F
Sbjct: 281 AALGYLRF 288
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.331    0.145    0.399 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 466,190
Number of extensions: 601
Number of successful extensions: 47
Number of sequences better than 10000.0: 47
Number of HSP's gapped: 47
Number of HSP's successfully gapped: 47
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.2 bits)
S2: 28 (15.4 bits)

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