Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results 
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done




                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_066124                                                              21     229
XP_006717999                                                           21     229
NP_001073991                                                           15    9605
NP_055559                                                              15    9605
NP_001127853                                                           15    9605
NP_612388                                                              15    9605
NP_001140198                                                           15    9605
NP_115813                                                              15    9605
NP_037375                                                              15    9605
XP_005248236                                                           15    9605
XP_005248234                                                           15    9605
XP_005265673                                                           15    9605
XP_005265672                                                           15    9605
XP_005265671                                                           15    9605
XP_005265670                                                           15    9605
XP_005265669                                                           15    9605
XP_006713493                                                           15    9605
XP_006713492                                                           15    9605
XP_005265668                                                           15    9605
XP_005271331                                                           15    9605
XP_006711040                                                           15    9605
XP_006711039                                                           15    9605



>NP_066124
          Length = 1114

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    AAKLMDTYD 9
            AAKLMDT+D
Sbjct: 1105 AAKLMDTFD 1113





>XP_006717999
          Length = 1207

 Score = 20.8 bits (42), Expect =   229
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1    AAKLMDTYD 9
            AAKLMDT+D
Sbjct: 1198 AAKLMDTFD 1206





>NP_001073991
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   AAKLMDTYD 9
           AAKL   YD
Sbjct: 428 AAKLAQLYD 436





>NP_055559
          Length = 795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AKLMDTY 8
           AK+MDT+
Sbjct: 610 AKVMDTH 616





>NP_001127853
          Length = 817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AKLMDTY 8
           AK+MDT+
Sbjct: 632 AKVMDTH 638





>NP_612388
          Length = 378

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KLMDTY 8
           KLM+TY
Sbjct: 339 KLMETY 344





>NP_001140198
          Length = 350

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/6 (83%), Positives = 6/6 (100%)

Query: 3   KLMDTY 8
           KLM+TY
Sbjct: 311 KLMETY 316





>NP_115813
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AKLMDTYD 9
           AK+MD Y+
Sbjct: 542 AKVMDGYE 549





>NP_037375
          Length = 468

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 6/7 (85%)

Query: 3   KLMDTYD 9
           KL+D YD
Sbjct: 115 KLIDDYD 121





>XP_005248236
          Length = 1262

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   AAKLMDTYD 9
           AAKL   YD
Sbjct: 428 AAKLAQLYD 436





>XP_005248234
          Length = 1620

 Score = 15.4 bits (28), Expect =  9605
 Identities = 6/9 (66%), Positives = 6/9 (66%)

Query: 1   AAKLMDTYD 9
           AAKL   YD
Sbjct: 428 AAKLAQLYD 436





>XP_005265673
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AKLMDTY 8
           AK+MDT+
Sbjct: 496 AKVMDTH 502





>XP_005265672
          Length = 681

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AKLMDTY 8
           AK+MDT+
Sbjct: 496 AKVMDTH 502





>XP_005265671
          Length = 795

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AKLMDTY 8
           AK+MDT+
Sbjct: 610 AKVMDTH 616





>XP_005265670
          Length = 817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AKLMDTY 8
           AK+MDT+
Sbjct: 632 AKVMDTH 638





>XP_005265669
          Length = 817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AKLMDTY 8
           AK+MDT+
Sbjct: 632 AKVMDTH 638





>XP_006713493
          Length = 817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AKLMDTY 8
           AK+MDT+
Sbjct: 632 AKVMDTH 638





>XP_006713492
          Length = 817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AKLMDTY 8
           AK+MDT+
Sbjct: 632 AKVMDTH 638





>XP_005265668
          Length = 817

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/7 (71%), Positives = 7/7 (100%)

Query: 2   AKLMDTY 8
           AK+MDT+
Sbjct: 632 AKVMDTH 638





>XP_005271331
          Length = 606

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AKLMDTYD 9
           AK+MD Y+
Sbjct: 542 AKVMDGYE 549





>XP_006711040
          Length = 629

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AKLMDTYD 9
           AK+MD Y+
Sbjct: 542 AKVMDGYE 549





>XP_006711039
          Length = 642

 Score = 15.4 bits (28), Expect =  9605
 Identities = 5/8 (62%), Positives = 7/8 (87%)

Query: 2   AKLMDTYD 9
           AK+MD Y+
Sbjct: 555 AKVMDGYE 562





  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.316    0.126    0.343 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 403,290
Number of extensions: 429
Number of successful extensions: 22
Number of sequences better than 10000.0: 22
Number of HSP's gapped: 22
Number of HSP's successfully gapped: 22
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (15.7 bits)
S2: 28 (15.4 bits)

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