Cancertope

In silico Platform for designing genome-based
Personalized immunotherapy or Vaccine against Cancer

Blast-Search of mutated query peptide against human proteome

BLAST Search Results
BLASTP 2.2.15 [Oct-15-2006]


Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= User_input
         (9 letters)

Database: HUMAN_PROTEOME_FASTA 
           71,491 sequences; 45,948,801 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

NP_001895                                                              18    1135
NP_001091680                                                           18    1135
NP_001091679                                                           18    1135
XP_006713048                                                           18    1135
XP_006713047                                                           18    1135
XP_006713046                                                           18    1135
XP_005264943                                                           18    1135
NP_002221                                                              17    3301
NP_068831                                                              17    3301
XP_006721941                                                           17    3301
XP_006721940                                                           17    3301
XP_006721939                                                           17    3301
XP_006721938                                                           17    3301
XP_006721937                                                           17    3301
XP_006721936                                                           17    3301
XP_006721935                                                           17    3301
XP_006721934                                                           17    3301
XP_005257370                                                           17    3301
NP_001229825                                                           16    7355
NP_001229826                                                           16    7355
NP_055477                                                              16    7355
NP_001129501                                                           16    7355
XP_006724448                                                           16    7355
XP_006724447                                                           16    7355
XP_005261922                                                           16    7355
XP_005261921                                                           16    7355
XP_005261920                                                           16    7355
XP_005261919                                                           16    7355
>NP_001895
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF+MS
Sbjct: 655 AAAVLFRMS 663
>NP_001091680
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF+MS
Sbjct: 655 AAAVLFRMS 663
>NP_001091679
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF+MS
Sbjct: 655 AAAVLFRMS 663
>XP_006713048
          Length = 720

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF+MS
Sbjct: 655 AAAVLFRMS 663
>XP_006713047
          Length = 774

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF+MS
Sbjct: 648 AAAVLFRMS 656
>XP_006713046
          Length = 774

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF+MS
Sbjct: 648 AAAVLFRMS 656
>XP_005264943
          Length = 781

 Score = 18.5 bits (36), Expect =  1135
 Identities = 8/9 (88%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF+MS
Sbjct: 655 AAAVLFRMS 663
>NP_002221
          Length = 745

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF++S
Sbjct: 645 AAAVLFRIS 653
>NP_068831
          Length = 745

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF++S
Sbjct: 645 AAAVLFRIS 653
>XP_006721941
          Length = 745

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF++S
Sbjct: 645 AAAVLFRIS 653
>XP_006721940
          Length = 745

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF++S
Sbjct: 645 AAAVLFRIS 653
>XP_006721939
          Length = 745

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF++S
Sbjct: 645 AAAVLFRIS 653
>XP_006721938
          Length = 745

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF++S
Sbjct: 645 AAAVLFRIS 653
>XP_006721937
          Length = 745

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF++S
Sbjct: 645 AAAVLFRIS 653
>XP_006721936
          Length = 745

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF++S
Sbjct: 645 AAAVLFRIS 653
>XP_006721935
          Length = 762

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF++S
Sbjct: 662 AAAVLFRIS 670
>XP_006721934
          Length = 783

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF++S
Sbjct: 683 AAAVLFRIS 691
>XP_005257370
          Length = 783

 Score = 16.9 bits (32), Expect =  3301
 Identities = 7/9 (77%), Positives = 9/9 (100%)

Query: 1   AAAVLFQMS 9
           AAAVLF++S
Sbjct: 683 AAAVLFRIS 691
>NP_001229825
          Length = 1603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    AAVLFQM 8
            AAVLF+M
Sbjct: 1395 AAVLFEM 1401
>NP_001229826
          Length = 1503

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    AAVLFQM 8
            AAVLF+M
Sbjct: 1295 AAVLFEM 1301
>NP_055477
          Length = 1572

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    AAVLFQM 8
            AAVLF+M
Sbjct: 1364 AAVLFEM 1370
>NP_001129501
          Length = 1594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    AAVLFQM 8
            AAVLF+M
Sbjct: 1386 AAVLFEM 1392
>XP_006724448
          Length = 1490

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    AAVLFQM 8
            AAVLF+M
Sbjct: 1282 AAVLFEM 1288
>XP_006724447
          Length = 1516

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    AAVLFQM 8
            AAVLF+M
Sbjct: 1308 AAVLFEM 1314
>XP_005261922
          Length = 1525

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    AAVLFQM 8
            AAVLF+M
Sbjct: 1317 AAVLFEM 1323
>XP_005261921
          Length = 1581

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    AAVLFQM 8
            AAVLF+M
Sbjct: 1373 AAVLFEM 1379
>XP_005261920
          Length = 1594

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    AAVLFQM 8
            AAVLF+M
Sbjct: 1386 AAVLFEM 1392
>XP_005261919
          Length = 1603

 Score = 15.8 bits (29), Expect =  7355
 Identities = 6/7 (85%), Positives = 7/7 (100%)

Query: 2    AAVLFQM 8
            AAVLF+M
Sbjct: 1395 AAVLFEM 1401
  Database: HUMAN_PROTEOME_FASTA
    Posted date:  May 26, 2014 10:46 AM
  Number of letters in database: 45,948,801
  Number of sequences in database:  71,491
  
Lambda     K      H
   0.336    0.125    0.300 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 71491
Number of Hits to DB: 289,744
Number of extensions: 290
Number of successful extensions: 28
Number of sequences better than 10000.0: 28
Number of HSP's gapped: 28
Number of HSP's successfully gapped: 28
Length of query: 9
Length of database: 45,948,801
Length adjustment: 0
Effective length of query: 9
Effective length of database: 45,948,801
Effective search space: 413539209
Effective search space used: 413539209
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 15 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 28 (16.6 bits)
S2: 28 (15.4 bits)

CANCERTOPE    |     Raghava's Group    |     IMTECH    |     CSIR    |     CRDD    |     GPSR Package