This module of TumorHPD allows user to design tumor homing peptides. This module generates all possible mutations in a query peptide submitted by the user. All possible mutants are generated (through amino acid substitution at single position at a time) to get the optimized tumor homing peptide . It predicts whether peptide and mutants of peptide are tumor homing peptides. User can select the physicochemical properties (such as hydrophobicity, charge, hydrophilicity etc.) to be displayed.