Please click on the ID to see detailed information about each entry.
The total number entries retrieved from this search are| ID | Sequence | Name | Nature of peptide or cargo | Assay | Tissue permeability | Tissue Sample | PUBMED ID |
|---|---|---|---|---|---|---|---|
| 1080 | CSNLSTCVLGKLSQELH KLQTYPRTNTGSGTP | sCT | Cell penetrating peptide | Vertical Franz diffusion cell, HPLC | Cumulative amounts 0.67 ± 0.10 mg/cm2 and fluxes 0.67 ± 0.10 mg/cm2·h | Viable epidermis and dermis (VED) abdominal skin of Sprague Dawley (SD) rats | 22564052 |
| 1081 | CSNLSTCVLGKLSQELH KLQTYPRTNTGSGTP | sCT | Cell penetrating peptide | Vertical Franz diffusion cell, HPLC | Cumulative amounts 0.33 ± 0.09 mg/cm2 and fluxes 0.11 ± 0.03 mg/cm2·h | Viable epidermis and dermis (VED) abdominal skin of Sprague Dawley (SD) rats | 22564052 |
| 1082 | CSNLSTCVLGKLSQELH KLQTYPRTNTGSGTP | sCT | Cell penetrating peptide | Vertical Franz diffusion cell, HPLC | Cumulative amounts 0.26 ± 0.02 mg/cm2 and fluxes 0.04 ± 0.00 mg/cm2·h | Viable epidermis and dermis (VED) abdominal skin of Sprague Dawley (SD) rats | 22564052 |
| 1113 | GGGARKKAAKAARKK AAKAARKKAAKAARK KAAKA | POD-GFP [POD (peptide for ocular delivery)] | Cell penetrating peptide | Fluorescence microscopy | GFP-fluorescence was 23.4 ±8.8, p < 0.05 | Epidermis of skin of C57BL6/J mice | 19733192 |
| 1215 | SVSEIQLMHNLGKHL NSMERVEWLRKKLQD VHNF | Parathyroid Hormone (PTH) | PTH is an important regulator of calcium and phosphorus metabolism and used for treatment of psoriasis. | Franz cell | <1% PTH dissolved in normal saline recovered in the lower chamber of the Franz cell after 24 h | Surgically obtained adult abdominal human epidermis | 12932245 |
| 1216 | SVSEIQLMHNLGKHL NSMERVEWLRKKLQD VHNF | Parathyroid Hormone (PTH) | PTH is an important regulator of calcium and phosphorus metabolism and used for treatment of psoriasis. | Franz cell | <1% PTH dissolved in propylene glycol recovered in the lower chamber of the Franz cell after 24 h | Surgically obtained adult abdominal human epidermis | 12932245 |
| 1217 | SVSEIQLMHNLGKHL NSMERVEWLRKKLQD VHNF | Parathyroid Hormone (PTH) | PTH is an important regulator of calcium and phosphorus metabolism and used for treatment of psoriasis. | Franz cell | 45% PTH formulated in Novasome A cream recovered in the lower chamber of the Franz cell after 24 h | Surgically obtained adult abdominal human epidermis | 12932245 |
| 1226 | CSNLSTCVLGKLSQEL HKLQTYPRTNTGSGTP | Salmon calcitonin (sCT) | A peptide hormone which inhibits bone resorption by inhibiting the activity of osteoclasts. | Radioimmunoassay | Area Under the Curve0–120 min (ng·min/ml)=19.8±2.9 , Absolute Bioavailability (%)=33.2 , Relative Bioavailability (%)=68.6 | Stratum corneum of the stomach of SD male rats | 11337153 |
| 1227 | CSNLSTCVLGKLSQEL HKLQTYPRTNTGSGTP | Salmon calcitonin (sCT) | A peptide hormone which inhibits bone resorption by inhibiting the activity of osteoclasts. | Radioimmunoassay | Area Under the Curve0–120 min (ng·min/ml)=43.0±5.0 , Absolute Bioavailability (%)=37.0 , Relative Bioavailability (%)=76.5 | Stratum corneum of the stomach of SD male rats | 11337153 |
| 1228 | CSNLSTCVLGKLSQEL HKLQTYPRTNTGSGTP | Salmon calcitonin (sCT) | A peptide hormone which inhibits bone resorption by inhibiting the activity of osteoclasts. | Radioimmunoassay | Area Under the Curve0–120 min (ng·min/ml)=72.2±7.3 , Absolute Bioavailability (%)=32.5 , Relative Bioavailability (%)=67.2 | Stratum corneum of the stomach of SD male rats | 11337153 |
| 1265 | SNLST-Asu-VLGKLSQELH KLQTYPRTDVGAGTP | Elcatonin | It stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | Calcium C-Test Wako kit, Ames method, Alkaline Phospha K-Test and ANOVA | Parameters studied: Ca(mg/dl)- 8.83±0.20/8.94±0.17(control), P(mg/dl)- 5.32±0.35/5.58±0.55(control) and Alkaline phosphatase- 23.69±1.16/18.83±0.75(control) | Abdominal skin of female wistar rats | 8268857 |
| 1266 | SNLST-Asu-VLGKLSQELH KLQTYPRTDVGAGTP | Elcatonin | It stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | Calcium C-Test Wako kit, Ames method, Alkaline Phospha K-Test and ANOVA | Parameters studied: Ca(mg/dl)- 8.80±0.27/8.94±0.17(control), P(mg/dl)- 5.22±0.36/5.58±0.55(control) and Alkaline phosphatase- 22.21±4.01/18.83±0.75(control) | Abdominal skin of female wistar rats | 8268857 |
| 1335 | SNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | Elcatonin | It stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | o-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Area under the curve(mg.h/dl)=30.99±11.75 , Area under the first moment curve(mg.h2/dl)=371.41±159.80 , The mean residence time(h)=12.06±1.99 , Apparent bioavailability(%)=2.68. | Stratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | 2054872 |
| 1336 | SNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | Elcatonin | It stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | o-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Area under the curve(mg.h/dl)=46.25±19.25 , Area under the first moment curve(mg.h2/dl)=623.71±233.74 , The mean residence time(h)=13.81±2.36 , Apparent bioavailability(%)=3.99. | Stratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | 2054872 |
| 1337 | SNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | Elcatonin | It stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | o-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Area under the curve(mg.h/dl)=36.13±21.93 , Area under the first moment curve(mg.h2/dl)=445.49±248.06 , The mean residence time(h)=12.83±1.68 , Apparent bioavailability(%)=3.12. | Stratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | 2054872 |
| 1338 | SNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | Elcatonin | It stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | o-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Area under the curve(mg.h/dl)=17.25±10.07 , Area under the first moment curve(mg.h2/dl)=271.52±106.34 , The mean residence time(h)=18.16±6.19 , Apparent bioavailability(%)=1.49. | Stratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | 2054872 |
| 1339 | SNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | Elcatonin | It stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | o-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Area under the curve(mg.h/dl)=53.50±14.96 , Area under the first moment curve(mg.h2/dl)=752.04±298.40 , The mean residence time(h)=13.66±3.46 , Apparent bioavailability(%)=4.62. | Stratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | 2054872 |
| 1340 | SNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | Elcatonin | It stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | o-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Area under the curve(mg.h/dl)=31.97±17.89 , Area under the first moment curve(mg.h2/dl)=505.37±238.24 , The mean residence time(h)=16.32±2.35 , Apparent bioavailability(%)=2.76. | Stratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | 2054872 |
| 1341 | SNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | Elcatonin | It stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | o-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Area under the curve(mg.h/dl)=40.85±20.01 , Area under the first moment curve(mg.h2/dl)=513.32±292.53 , The mean residence time(h)=12.34±2.37 , Apparent bioavailability(%)=3.53. | Stratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | 2054872 |
| 1342 | SNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | Elcatonin | It stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | o-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Area under the curve(mg.h/dl)=26.40±20.66 , Area under the first moment curve(mg.h2/dl)=341.64±271.20 , The mean residence time(h)=13.91±3.02 , Apparent bioavailability(%)=2.28. | Stratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | 2054872 |
| 1343 | SNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | Elcatonin | It stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | o-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Area under the curve(mg.h/dl)=35.0216.72 , Area under the first moment curve(mg.h2/dl)=433.42±114.39 , The mean residence time(h)=13.37±3.66 , Apparent bioavailability(%)=3.02. | Stratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | 2054872 |
| 1344 | SNLST-Asu-VLGKLSQEL HKLQTYPRTDVGAGTP | Elcatonin | It stimulates osteoblastic bone formation in addition to inhibiting osteoclastic bone resorption | o-cresolphthalein complexone method using Calcium C-Test Wako and 0.01 ml plasma, pharmacokinetic and statistical analysis | Area under the curve(mg.h/dl)=35.23±33.53 , Area under the first moment curve(mg.h2/dl)=490.35±444.31 , The mean residence time(h)=16.31±6.88 , Apparent bioavailability(%)=3.04. | Stratum corneum of the abdominal area of male Wistar rats(0.5g ointment/4 cm2/rat) | 2054872 |
| 1381 | DLPVLQLTHPPGVRRV YHIQAGLPDPFQPPS | HSV-1 gD 22-52 (group-1) | Intranasal aministration of HSV-gD peptides plus CpG can induce local ocular mucosal and systemic T-cell responses | FACS | Detectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels. | Nasal cavity of New Zealand White rabbits | 20089796 |
| 1382 | QPPSLPITVYAVLERA CRSVLLNAPSEAPQIVR | HSV-1 gD 49-82 (group-2) | Intranasal immunizations with group 2 peptides induced strong CD4+ T cell proliferation in the conjunctiva. | FACS | Detectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels. | Nasal cavity of New Zealand White rabbits | 20089796 |
| 1385 | NKSLGACPIRTQPRW NYYDSFSAVSEDNLGF | HSV-1 gD 121-152 (group-1) | Intranasal aministration of HSV-gD peptides plus CpG can induce local ocular mucosal and systemic T-cell responses | FACS | Detectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels | Nasal cavity of New Zealand White rabbits | 20089796 |
| 1386 | EDNLGFLMHSPSFETSGT YLRLVKINDWTEITQF | HSV-1 gD 146-179 (group-2) | Intranasal immunizations with group 2 peptides induced strong CD4+ T cell proliferation in the conjunctiva. | FACS | Detectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels | Nasal cavity of New Zealand White rabbits | 20089796 |
| 1387 | ITQFILEHRAKGSCKY ALPLRIPPSACLSPQ | HSV-1 gD 176-206 (group-3) | Intranasal aministration of HSV-gD peptides plus CpG can induce local ocular mucosal and systemic T-cell responses | FACS | Detectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels | Nasal cavity of New Zealand White rabbits | 20089796 |
| 1388 | SACLSPQAYQQGVTV DSIGMLPRFIPENQR TVAVY | HSV-1 gD 200-234 (group-2) | Intranasal immunizations with group 2 peptides induced strong CD4+ T cell proliferation in the conjunctiva. | FACS | Detectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels | Nasal cavity of New Zealand White rabbits | 20089796 |
| 1391 | APQIPPNWHIPSIQDA ATPYHPPATPNNMGL | HSV-1 gD 287-317 (group-2) | Intranasal immunizations with group 2 peptides induced strong CD4+ T cell proliferation in the conjunctiva. | FACS | Detectable HSV-1-specific CD4+ T cell responses were induced at the local (conjunctiva) and systemic (spleen) levels | Nasal cavity of New Zealand White rabbits | 20089796 |
| 1504 | DLPVLQLTDPPGVRRV YHIQAGLPDPFQPPS | gD 22-52 (group 1) | not mentioned | ELISA, Antibody assay, Peptide specific T-cell assays | Induced higher IgA response. | eye | 15603887 |
| 1505 | QPPSLPITVYYAVLERA CRSVLLNAPSEAPQIVR | gD 49-82 (group 1) | not mentioned | ELISA, Antibody assay, Peptide specific T-cell assays | Gave lower but significant responses (p <0.05) | eye | 15603887 |
| 1508 | NKSLGACPIRTQPRWN YYDSFSAVSEDNLGFL | gD 121-152 (group 2) | not mentioned | ELISA, Antibody assay, Peptide specific T-cell assays | Gave lower but significant responses (p <0.05) | eye | 15603887 |
| 1509 | EDNLGFLMHAPAFETAG TYLRLVKINDWTEITQF | gD 146-179 (group 2) | not mentioned | ELISA, Antibody assay, Peptide specific T-cell assays | Induced higher IgA response | eye | 15603887 |
| 1510 | TQFILEHRAKGSCKY ALPLRIPPSACLSPQ | gD 176-206 (group 2) | not mentioned | ELISA, Antibody assay, Peptide specific T-cell assays | Induced higher IgA response | eye | 15603887 |
| 1511 | SACLSPQAYQQGVTV DSIGMLPRFIPENQR TVAVY | gD 200-234 (group 3) | not mentioned | ELISA, Antibody assay, Peptide specific T-cell assays | Gave lower but significant responses (p <0.05) | eye | 15603887 |
| 1513 | APQIPPNWHIPSIQDA ATPYHPPATPNNMGL | gD 287-317 (group 3) | not mentioned | ELISA, Antibody assay, Peptide specific T-cell assays | Gave lower but significant responses (p <0.05) | eye | 15603887 |
| 1525 | GGG(ARKKAAKA)4 | L-POD (lissamine- conjugated peptide for ocular delivery) | A novel cell-penetrating peptide POD has the ability to penetrate and deliver fluorophores, siRNA, DNA and quantum dots to cells in culture and retinal and ocular tissues in vivo. It also acts as a microbicide, potentially providing a safer and more efficacious method of delivering molecules t | Fluorescence-activated cell sorting (FACS), Vital staining with Lissamine | L-POD bound strongly to the cornea, sclera and the dura of the optic nerve in vivo. In contrast, lissamine only weakly stained the cornea and sclera and did not stain the dura of the optic nerve. | Cornea of male C57BL/6J mice | 17923842 |
| 1606 | CSNLSTCVLGKLSQEL HKLQTYPRTNTGSGTP | Salmon calcitonin | Not mentioned | ELISA, noncompartmental analysis using WinNonlin | Iontophoretic patches delivered SCT at an average infusion rate of 177.9±58.7 ng/(min kg) and an average steady state concentration of 7.58±1.35 ng/ml was achieved. | Abdominal skin of hairless rats | 15907605 |
| 1644 | CGNLSTCMLGTYTQ DFNKFHTFPQTAIGVGAP | thyrocalcitonin | Not mentioned | permeability coefficient for transdermal iontophoretic transport of peptide/ protein drugs from polyacrylamide hydrogels was measured. | 6.20 (cm/sec) * 10 8 | skin of hairless rat | 8321834 |
| 1647 | CGNLSTCMLGTYTQ DFNKFHTFPQTAIGVGAP | thyrocalcitonin | Not mentioned | permeability coefficient for transdermal iontophoretic transport of peptide/ protein drugs from p-HEMA hydrogels was measured. | 1.95(cm/sec) * 10 8 | skin of hairless rat | 8321834 |