Please click on the ID to see detailed information about each entry.
The total number entries retrieved from this search are| ID | Sequence | Name | Nature of peptide or cargo | Assay | Tissue permeability | Tissue Sample | PUBMED ID |
|---|---|---|---|---|---|---|---|
| 1020 | ACSSSPSKHCG | TDN | TD-1 has been testified to enhanced insulin transdermal delivery through hair follicles | Confocal Laser Scanning Microscopy | Significant permeability of the peptide can be seen in confocal images | Male SD rats skin cells | 23391375 |
| 1104 | KWLNALLHHGLNCAK GVLA | HG1 | Antimicrobial | Confocal microscopy, HPLC | Significant permeability of the peptide can be seen in confocal images | ICR mice skin | 21220538 |
| 1117 | pGlu-HWSYwLRPG | Triptorelin | Luteinizing hormone releasing hormone (LHRH) superagonist | Franz diffusion cell, HPLC | 64.9±8.8% degraded | Interior skin surface of dermatomed skin (DS) of porcine | 19486932 |
| 1118 | pGlu-HWSYwLRPG | Triptorelin | Luteinizing hormone releasing hormone (LHRH) superagonist | Franz diffusion cell, HPLC | 15±4.1% degraded | Interior skin surface of heat separated epidermis (HSE) of porcine | 19486932 |
| 1119 | pGlu-HWSYwLRPG | Triptorelin | Luteinizing hormone releasing hormone (LHRH) superagonist | Franz diffusion cell, HPLC | 100% degraded | Interior skin surface of full thickness skin (FTS) of porcine | 19486932 |
| 1120 | pGlu-HWSYwLRPG | Triptorelin | Luteinizing hormone releasing hormone (LHRH) superagonist | Franz diffusion cell, HPLC | 87.8±4.4% degraded | Interior skin surface of dermatomed skin (DS) of porcine | 19486932 |
| 1121 | pGlu-HWSYwLRPG | Triptorelin | Luteinizing hormone releasing hormone (LHRH) superagonist | Franz diffusion cell, HPLC | 51.3±6% degraded | Interior skin surface of heat separated epidermis (HSE) of porcine | 19486932 |
| 1131 | LIGR | LIGR | Activation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | Vybrant Phagocytosis Assay | Significant increase in the LIGR-induced keratinocyte phagocytosis observed using Vybrant Phagocytosis Assay | HaCaT keratinocytes | 18426410 |
| 1132 | LIGR | LIGR | Activation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | Fontana-Mason (F&M) stain | The increase in pigment deposition induced by peptide can be seen in the Fontana-Mason (F&M) stained microscopic images of mice skin sections | Dorsum skin of SKH-1 hairless female mice | 18426410 |
| 1133 | LIGR | LIGR | Activation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | Fontana-Mason (F&M) stain | The increase in pigment deposition induced by peptide can be seen in the Fontana-Mason (F&M) stained microscopic images of swine skin sections | Dorsum skin of pigmented yucatan microswine | 18426410 |
| 1134 | LIGR | LIGR | Activation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | Fontana-Mason (F&M) stain | The increase in pigment deposition induced by peptide can be seen in the Fontana-Mason (F&M) stained microscopic images of Human skin section skin sections | Human skin samples grafted onto SCID mice | 18426410 |
| 1135 | SLIGR | SLIGR | Activation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | Vybrant Phagocytosis Assay | Significant increase in the LIGR-induced keratinocyte phagocytosis observed using Vybrant Phagocytosis Assay | HaCaT keratinocytes | 18426410 |
| 1136 | SLIGR | SLIGR | Activation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | Fontana-Mason (F&M) stain | The increase in pigment deposition induced by peptide can be seen in the Fontana-Mason (F&M) stained microscopic images of mice skin sections | Dorsum skin of SKH-1 hairless female mice | 18426410 |
| 1137 | SLIGR | SLIGR | Activation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | Fontana-Mason (F&M) stain | The increase in pigment deposition induced by peptide can be seen in the Fontana-Mason (F&M) stained microscopic images of swine skin sections | Dorsum skin of pigmented yucatan microswine | 18426410 |
| 1138 | SLIGR | SLIGR | Activation of the human PAR-2 receptor, increase melanin depositionin vitro and in vivo | Fontana-Mason (F&M) stain | The increase in pigment deposition induced by peptide can be seen in the Fontana-Mason (F&M) stained microscopic images of Human skin section skin sections | Human skin samples grafted onto SCID mice | 18426410 |
| 1143 | r–nle–nle–nle–r–nle–nle–nle–g–y | RDP58 | Immunomodulator | Histological assay using bright field microscopy | It can be clearly seen from the histological images that topical application of RDP58results in significant decrease in tthe hickness of the ear skin as compared to control (TPA applied ear skin) | Ear of mice | 16117788 |
| 1194 | Mpr-YFQNCPrG | Desmopressin | It is a peptide hormone that is used chiefly for treatment of enuresis | Radioimmunoassay | 10 ng/ml serum conc. of desmopressin after ~100 min of coated microneedle array application | Lateral skin areas of the thorax of hairless guinea pigs | 15212882 |
| 1195 | Mpr-YFQNCPrG | Desmopressin | It is a peptide hormone that is used chiefly for treatment of enuresis | Radioimmunoassay | 1 ng/ml serum conc. of desmopressin after ~250 min of coated microneedle array application | Lateral skin areas of the thorax of hairless guinea pigs | 15212882 |
| 1196 | Mpr-YFQNCPrG | Desmopressin | It is a peptide hormone that is used chiefly for treatment of enuresis | Radioimmunoassay | 0.8 ng/ml serum conc. of desmopressin after ~350 min of coated microneedle array application | Lateral skin areas of the thorax of hairless guinea pigs | 15212882 |
| 1199 | pGlu-HWSYGLRPG | LHRH | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | LHRH flux= 2.37 ± 0.94 µg h−1 cm−2 at 100% DC | Human cadaver skin | 14757511 |
| 1200 | pGlu-HWSYGLRPG | LHRH | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | LHRH flux= 9.87 ± 4.91 µg h−1 cm−2 at 75% pulsed DC | Human cadaver skin | 14757511 |
| 1201 | pGlu-HWSYGLRPG | LHRH | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | LHRH flux= 5.57 ± 2.27 µg h−1 cm−2 at 50% pulsed DC | Human cadaver skin | 14757511 |
| 1202 | pGlu-HWSYGLRPG | LHRH | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | LHRH flux= 1.21 ± 0.76 µg h−1 cm−2 at 75%+/25%− AC | Human cadaver skin | 14757511 |
| 1203 | pGlu-HWSYGLRPG | LHRH | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | LHRH flux= 0.006 ± 0.004 µg h−1 cm−2 at 50%+/50%− AC | Human cadaver skin | 14757511 |
| 1204 | pGlu-HWSY-D-2-Nal-LRPG | Nafarelin | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | Nafarelin flux= 1.99 ± 2.04 µg h−1 cm−2 at 100% DC | Human cadaver skin | 14757511 |
| 1205 | pGlu-HWSY-D-2-Nal-LRPG | Nafarelin | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | Nafarelin flux= 6.47 ± 0.87 µg h−1 cm−2 at 75% DC | Human cadaver skin | 14757511 |
| 1206 | pGlu-HWSY-D-2-Nal-LRPG | Nafarelin | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | Nafarelin flux= 0.96 ± 0.79 µg h−1 cm−2 at 50% pulsed DC | Human cadaver skin | 14757511 |
| 1207 | pGlu-HWSY-D-2-Nal-LRPG | Nafarelin | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | Nafarelin flux= 3.33 ± 1.04 µg h−1 cm−2 at 75%+/25%- AC | Human cadaver skin | 14757511 |
| 1208 | pGlu-HWSY-D-2-Nal-LRPG | Nafarelin | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | Nafarelin flux= 0.15 ± 0.09 µg h−1 cm−2 at 50%+/50%- AC | Human cadaver skin | 14757511 |
| 1209 | pGlu-HWSYGLRPG | LHRH | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | LHRH flux= 12.39 ± 5.32 µg h−1 cm−2 at 75% pulsed DC (500 Hz) | Epidermis of human cadaver skin | 14757511 |
| 1210 | pGlu-HWSYGLRPG | LHRH | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | LHRH flux= 5.97 ± 3.20 µg h−1 cm−2 at 50% pulsed DC (500 Hz) | Epidermis of human cadaver skin | 14757511 |
| 1211 | pGlu-HWSYGLRPG | LHRH | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | LHRH flux=9.07 ± 4.28 µg h−1 cm−2 at 25% pulsed DC (500 Hz) | Epidermis of human cadaver skin | 14757511 |
| 1212 | pGlu-HWSYGLRPG | LHRH | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | LHRH flux= 8.70±3.56 µg h−1 cm−2 at 75% pulsed DC (5 Hz) | Epidermis of human cadaver skin | 14757511 |
| 1213 | pGlu-HWSYGLRPG | LHRH | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | LHRH flux= 7.31±1.94 µg h−1 cm−2 at 50% pulsed DC (5 Hz) | Epidermis of human cadaver skin | 14757511 |
| 1214 | pGlu-HWSYGLRPG | LHRH | Peptides containing closely juxtapositioned cationic and lipohilic residues are able to inhibit their own transport across the skin even under the influence of iontophoretic current. | HPLC | LHRH flux= 9.35±1.98 µg h−1 cm−2 at 25% pulsed DC (5 Hz) | Epidermis of human cadaver skin | 14757511 |
| 1229 | pGlu-HP | Thyrotropin-releasing hormone (TRH) | TRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | Cardiovascular parameters and blood gas values determined by collecting blood at different time intervals | On application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-11.1 ± 0.7, Basal skin blood flow(PU)-378 ± 47, Heart rate(min-1)-424 ± 26, Respiratory rate(min-1)-113 ± 8, pH-7.38 ± 0.02, pCO2(kPa)-7.07 ± 0.37 and pO2(kPa)-7.91 ± 0.25 | Stratum corneum of the abdominal area of male Sprague-Dawley rats | 11179600 |
| 1230 | pGlu-HP | Thyrotropin-releasing hormone (TRH) | TRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | Cardiovascular parameters and blood gas values determined by collecting blood at different time intervals | On application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-10.8 ± 1.0, Basal skin blood flow(PU)-421 ± 4, Heart rate(min-1)-417 ± 23, Respiratory rate(min-1)-118 ± 6, pH-7.39 ± 0.01, pCO2(kPa)-6.82 ± 0.27 and pO2(kPa)-8.43 ± 0.24 | Stratum corneum of the abdominal area of male Sprague-Dawley rats | 11179600 |
| 1231 | pGlu-HP | Thyrotropin-releasing hormone (TRH) | TRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | Cardiovascular parameters and blood gas values determined by collecting blood at different time intervals | On application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-10.5 ± 1.0, Basal skin blood flow(PU)-454 ± 23, Heart rate(min-1)-423 ± 23, Respiratory rate(min-1)-123 ± 6, pH-7.40 ± 0.02, pCO2(pKa)-6.46 ± 0.31 and pO2(pKa)-9.87 ± 1.49 | Stratum corneum of the abdominal area of male Sprague-Dawley rats | 11179600 |
| 1232 | pGlu-HP | Thyrotropin-releasing hormone (TRH) | TRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | Cardiovascular parameters and blood gas values determined by collecting blood at different time intervals | On application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-9.5 ± 0.8, Basal skin blood flow(PU)-348 ± 62, Heart rate(min-1)-419 ± 26, Respiratory rate(min-1)-115 ± 7, pH-7.37 ± 0.02, pCO2(pKa)-7.05 ± 0.56 and pO2(pKa)-7.39 ± 0.33 | Stratum corneum of the abdominal area of male Sprague-Dawley rats | 11179600 |
| 1233 | pGlu-HP | Thyrotropin-releasing hormone (TRH) | TRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | Cardiovascular parameters and blood gas values determined by collecting blood at different time intervals | On application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-11.3 ± 0.7, Basal skin blood flow(PU)-370 ± 55, Heart rate(min-1)-329 ± 12, Respiratory rate(min-1)-89 ± 5, pH-7.33 ± 0.01, pCO2(pKa)-8.31 ± 0.25 and pO2(pKa)-9.24 ± 1.03 | Stratum corneum of the abdominal area of male Sprague-Dawley rats | 11179600 |
| 1234 | pGlu-HP | Thyrotropin-releasing hormone (TRH) | TRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | Cardiovascular parameters and blood gas values determined by collecting blood at different time intervals | On application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-9.9 ± 0.8, Basal skin blood flow(PU)-358 ± 47, Heart rate(min-1)-349 ± 15, Respiratory rate(min-1)-101 ± 5, pH-7.33 ± 0.01, pCO2(pKa)-7.85 ± 0.23 and pO2(pKa)-9.30 ± 0.71 | Stratum corneum of the abdominal area of male Sprague-Dawley rats | 11179600 |
| 1235 | pGlu-HP | Thyrotropin-releasing hormone (TRH) | TRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | Cardiovascular parameters and blood gas values determined by collecting blood at different time intervals | On application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-9.0 ± 0.5, Basal skin blood flow(PU)-287 ± 51, Heart rate(min-1)-353 ± 14, Respiratory rate(min-1)-98 ± 4, pH-7.33 ± 0.01, pCO2(pKa)-7.72 ± 0.34 and pO2(pKa)-8.43 ± 0.63 | Stratum corneum of the abdominal area of male Sprague-Dawley rats | 11179600 |
| 1236 | pGlu-HP | Thyrotropin-releasing hormone (TRH) | TRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | Cardiovascular parameters and blood gas values determined by collecting blood at different time intervals | On application of TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-8.2 ± 0.4, Basal skin blood flow(PU)-244 ± 50, Heart rate(min-1)-359 ± 11, Respiratory rate(min-1)-91 ± 9, pH-7.35 ± 0.02, pCO2(pKa)-6.89 ± 0.33 and pO2(pKa)-10.8 ± 1.55 | Stratum corneum of the abdominal area of male Sprague-Dawley rats | 11179600 |
| 1237 | pGlu-3-methyl-HP | M-TRH | TRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | Cardiovascular parameters and blood gas values determined by collecting blood at different time intervals | On application of M-TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-11.2 ± 0.2, Basal skin blood flow(PU)-380 ± 44, Heart rate(min-1)-387 ± 18, Respiratory rate(min-1)-105 ± 10, pH-7.36 ± 0.03, pCO2(pKa)-7.42 ± 0.49 and pO2(pKa)-8.32 ± 0.70 | Stratum corneum of the abdominal area of male Sprague-Dawley rats | 11179600 |
| 1238 | pGlu-3-methyl-HP | M-TRH | TRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | Cardiovascular parameters and blood gas values determined by collecting blood at different time intervals | On application of M-TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-10.5 ± 0.5, Basal skin blood flow(PU)-305 ± 72, Heart rate(min-1)-385 ± 3, Respiratory rate(min-1)-113 ± 5, pH-7.39 ± 0.01, pCO2(pKa)-6.72 ± 0.08 and pO2(pKa)-7.99 ± 0.60 | Stratum corneum of the abdominal area of male Sprague-Dawley rats | 11179600 |
| 1239 | pGlu-3-methyl-HP | M-TRH | TRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | Cardiovascular parameters and blood gas values determined by collecting blood at different time intervals | On application of M-TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-10.1 ± 0.5, Basal skin blood flow(PU)-259 ± 69, Heart rate(min-1)-378 ± 4, Respiratory rate(min-1)-110 ± 8, pH-7.41 ± 0.01, pCO2(pKa)-6.51 ± 0.04 and pO2(pKa)-8.44 ± 0.46 | Stratum corneum of the abdominal area of male Sprague-Dawley rats | 11179600 |
| 1240 | pGlu-3-methyl-HP | M-TRH | TRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | Cardiovascular parameters and blood gas values determined by collecting blood at different time intervals | On application of M-TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-9.9 ± 0.8, Basal skin blood flow(PU)-202 ± 71, Heart rate(min-1)-372 ± 17, Respiratory rate(min-1)-101 ± 4, pH-7.40 ± 0.01, pCO2(pKa)-6.58 ± 0.20 and pO2(pKa)-8.73 ± 0.60 | Stratum corneum of the abdominal area of male Sprague-Dawley rats | 11179600 |
| 1241 | pGlu-3-methyl-HP | M-TRH | TRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | Cardiovascular parameters and blood gas values determined by collecting blood at different time intervals | On application of M-TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-11.0 ± 0.31, Basal skin blood flow(PU)-382 ± 32, Heart rate(min-1)-400 ± 8, Respiratory rate(min-1)-116 ± 7, pH-7.35 ± 0.01, pCO2(pKa)-7.73 ± 0.24 and pO2(pKa)-9.59 ± 1.04 | Stratum corneum of the abdominal area of male Sprague-Dawley rats | 11179600 |
| 1242 | pGlu-3-methyl-HP | M-TRH | TRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | Cardiovascular parameters and blood gas values determined by collecting blood at different time intervals | On application of M-TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-10.7 ± 0.31, Basal skin blood flow(PU)-294 ± 42, Heart rate(min-1)-404 ± 10, Respiratory rate(min-1)-116 ± 7, pH-7.36 ± 0.01, pCO2(pKa)-7.14 ± 0.22 and pO2(pKa)-8.57 ± 0.31 | Stratum corneum of the abdominal area of male Sprague-Dawley rats | 11179600 |
| 1243 | pGlu-3-methyl-HP | M-TRH | TRH has potential clinical value in the treatment of neurotrauma and various neurologic and psychiatric disorders besides its well known endocrinological effects | Cardiovascular parameters and blood gas values determined by collecting blood at different time intervals | On application of M-TRH, cardiovascular parameters and blood gas values:Mean arterial blood pressure(kPa)-10.3 ± 0.33, Basal skin blood flow(PU)-213 ± 48, Heart rate(min-1)-407 ± 13, Respiratory rate(min-1)-107 ± 9, pH-7.38 ± 0.01, pCO2(pKa)-6.62 ± 0.24 and pO2(pKa)-10.6 ± 1.13 | Stratum corneum of the abdominal area of male Sprague-Dawley rats | 11179600 |