==== Reference: Usmani SS, Bedi G, Samuel JS, Singh S, Kalra S, Kumar P, et al. (2017) THPdb: Database of FDA-approved peptide and protein therapeutics. PLoS ONE 12(7) e0181748.====

Browse result page of THPdb

The total number entries retrieved from this search are 118
IDThPPIDNamePeptide SequenceLengthFunctional ClassificationDiseaseBrandCompanyPhysical AppearanceRoute of AdministartionCategoryTarget
1001Th1001LepirudinLVYTDCTESGQNLCLCEGSN Full view65IaHematological,MetabolicRefludanBerlex LabsSterile, white, freeze-dried powderIntravenous infusionAntithrombins and Fibrinolytic Agents Prothrombin
1025Th1004Denileukin diftitoxMGADDVVDSSKSFVMENFSS Full view255IIbCancerOntakSeragen IncSterile, white, preservative-free, lyophilized powder.Intravenous(IV) administrationAntineoplastic Agents Interleukin-2 receptor subunit alpha,Interleukin-2 receptor subunit beta,Cytokine receptor common subunit gamma
1028Th1005EtanerceptLPAQVAFTPYAPEPGSTCRL Full view255IIaImmunologicalEnbrelImmunex CorpLyophilized powder.Subcutaneous injectionImmunosuppressive Agents Tumor necrosis factor,Tumor necrosis factor receptor superfamily member 1B,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c,Lymphotoxin-alpha,Low affinity immunoglobulin gamma Fc region re
1033Th1006BivalirudinFPRPGGGGNGDFEEIPEEYL Full view20IaHematological,MetabolicAngioxThe Medicines Company UK LtdPowder for concentrate for solutionInjectionAntithrombins Prothrombin
1055Th1009AlteplaseSYQVICRDEKTQMIYQQHQS Full view255IbHematological,MetabolicActivaseGenentech IncSterile, white to off-white, lyophilized powderIntravenousThrombolytic Agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1
1067Th1012ReteplaseSYQGNSDCYFGNGSAYRGTH Full view255IbHematological,MetabolicRetavaseCentocorSterile, white, lyophilized powderIntravenous InjectionFibrinolytic Agents, Thrombolytic agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1
1077Th1013Epoetin alfaAPPRLICDSRVLERYLLEAK Full view166IbHematologicalNanokineNanogen Pharmaceutical biotechnology, Vietnam)Sterile, white, lyophilized powder. The reconstituted preparation with 1 ml solvent (containing 0.9% benzyl alcohol) results in a clear, colorless solution.InjectionAnti-anemic Agents, Hematinics Erythropoietin receptor
1121Th1017SargramostimAPARSPSPSTQPWEHVNAIQ Full view127IbImmunologicalLeukineBerlex Laboratories IncSterile, preserved (1.1% benzyl alcohol), injectable solution (500 mcg/mL) and also as sterile, white, preservative free lyophilized powder (250 mcg) that requires reconstitution with 1 mL sterile water for InjectionSubcutaneous Injection (SC) or Intravenous infusion (IV)Immunosuppressive Agents Granulocyte-macrophage colony-stimulating factor receptor subunit alpha,Interleukin-3 receptor subunit alpha,Cytokine receptor common subunit beta,Syndecan-2,Bone marrow proteoglycan
1129Th1018SecretinHSDGTFTSELSRLRDSARLQ Full view27IVHormonal disordersSecreFloRepligen CorpLyophilized white powderIntravenous infusionDiagnostic Agents Secretin receptor
1135Th1019Peginterferon alfa-2bCDLPQTHSLGSRRTLMLLAQ Full view165IbImmunologicalPEG-IntronSchering CorpPowderSubcutaneous injectionImmunosuppressive Agents Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2
1136Th1019Peginterferon alfa-2bCDLPQTHSLGSRRTLMLLAQ Full view165IbImmunologicalUnitron PEGN.A.Lyophilized powderSubcutaneous injectionImmunosuppressive Agents Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2
1142Th1020AsparaginaseQMSLQQELRYIEALSAIVET Full view255IcCancerElsparMerck & Co. IncLyophilized plug or powderIntravenous or Intramuscular. Intravenous method dose has higher risk of allergic reaction, so often a test dose is given first.Antineoplastic Agents L-asparagine
1145Th1021Thyrotropin AlfaAlpha chain:APDVQDC< Full view204IVCancerThyrogenGenzyme IncLyophilized powderIntramuscular preferably the buttocksDiagnostic Agents Thyrotropin receptor
1148Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicAdvateN.A.Powder formIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1149Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicAlphanateN.A.Lyophilized powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1150Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicBioclateBaxter Healthcare Corporation, Hyland Division and Genetics Institute, Inc.Sterile, nonpyrogenic, off-white to faint yellow, lyophilized powderIntravenous infusionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1153Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHyate:CN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1154Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicKoate-HPN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1155Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicKogenate FSN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1156Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicMonarc-MN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1157Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicMonoclate-PN.A.Lyophilized powder for solutionIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1158Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicReFactoN.A.Lyophilized powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1159Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicXynthaN.A.Sterile, nonpyrogenic, preservative-free, freeze-dried powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1201Th1026AnistreplaseSYQVICRDEKTQMIYQQHQS Full view255IcHematological,MetabolicEminaseWulfing Pharma GmbHDry powderIntravenous infusionThrombolytic Agents, Fibrinolytic agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1
1210Th1028TenecteplaseSYQVICRDEKTQMIYQQHQS Full view255IbHematological,MetabolicTNKaseGenentech IncSterile, white to off-white, lyophilized powderIntravenous InjectionThrombolytic Agents, Fibrinolytic agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1,Plasminogen activator inhibitor 2,Tetranectin,Keratin, type II cytoskeletal 8,Annexin A2,Calreticulin,Calnexin,Prolow-density lipoprotein
1215Th1029MenotropinsAlpha-Chain(LH):APD< Full view222IbHormonal disordersMenopurN.A.Sterile, lyophilized powder which is reconstitution with sterile 0.9% Sodium Chloride Injection.Subcutaneous InjectionFertility Agents Follicle-stimulating hormone receptor,Lutropin-choriogonadotropic hormone receptor
1234Th1032Coagulation factor VIIaANAFLEELRPGSLERECKEE Full view255IbHematological,MetabolicNovoSevenNovo NordiskSterile, white lyophilized powderInjectionThrombotic Agents, Coagulants Coagulation factor X,Serine protease hepsin,Tissue factor pathway inhibitor,Vitamin K-dependent gamma-carboxylase,Coagulation factor VII,Tissue factor
1242Th1033OprelvekinGPPPGPPRVSPDPRAELDST Full view177IbCancer/HaemetologicalNeumegaGenetics Institute IncSterile, lyophilized powderSubcutaneous injectionCoagulants and Thrombotic Agents, Anti-neoplastic agents Interleukin-11 receptor subunit alpha
1246Th1034PaliferminSYDYMEGGDIRVRRLFCRTQ Full view140IbCancerKepivanceAmgen IncSterile, lyophilized powderIntravenous infusionAnti-Mucositis Agents Fibroblast growth factor receptor 2,Neuropilin-1,Fibroblast growth factor receptor 1,Fibroblast growth factor receptor 4,Fibroblast growth factor receptor 3,Basement membrane-specific heparan sulfate proteoglycan core protein
1252Th1035Glucagon recombinantHSQGTFTSDYSKYLDSRRAQ Full view29IVHormonal/Metabolic/geneticGlucaGenNovo NordiskSterile, lyophilized white powderSubcutaneous, Intramuscular, or Intravenous infusionHypoglycemic Agents Glucagon receptor,Glucagon-like peptide 2 receptor,Glucagon-like peptide 1 receptor
1253Th1035Glucagon recombinantHSQGTFTSDYSKYLDSRRAQ Full view29IVHormonal/Metabolic/geneticGlucagonEli LillyPowderSubcutaneously or Intramuscularly InjectionHypoglycemic Agents Glucagon receptor,Glucagon-like peptide 2 receptor,Glucagon-like peptide 1 receptor
1290Th1042CollagenaseMKRKCLSKRLMLAITMATIF Full view255IcHematologicalXiaflexAuxiliumSterile lyophilized powder (white cake)Intralesional InjectionN.A. Collagen alpha-1(I) chain,Collagen alpha-1(II) chain,Collagen alpha-1(III) chain,Collagen alpha-2(I) chain
1305Th1043RasburicaseSAVKAARYGKDNVRVYKVHK Full view255IcMetabolic/GeneticElitekSanofi-Synthelabo IncSterile, white to off-white, lyophilized powderIntravenous administrationAntihyperuricemic Agents, Gout suppressants Uric acid
1306Th1043RasburicaseSAVKAARYGKDNVRVYKVHK Full view255IcMetabolic/GeneticFasturtecN.A.Powder and solvent that are made upto make solution.Intravenous administartionAntihyperuricemic Agents, Gout suppressants Uric acid
1331Th1047Alpha-1-proteinase inhibitorEDPQGDAAQKTDTSHHDQDH Full view255IIaMetabolic/Geneti/RespiratoryAralastBaxterLyophilized powderIntravenous infusionSerine Proteinase Inhibitors, Enzyme replacement agents, trypsin inhibitors Neutrophil elastase
1332Th1047Alpha-1-proteinase inhibitorEDPQGDAAQKTDTSHHDQDH Full view255IIaMetabolic/Geneti/RespiratoryProlastinTalecris Biotherapeutics C formerly BayerLyophilized powderIntravenous infusionSerine Proteinase Inhibitors, Enzyme replacement agents, trypsin inhibitors Neutrophil elastase
1341Th1049Interferon beta-1aMSYNLLGFLQRSSNFQCQKL Full view166IbCancer/Infectious/ImmunologicalAvonexBiogen IncLyophilized powder vial, Sterile liquid as single used prefilled syringe and also available as single use prefilled autoinjector.Intramuscular InjectionImmunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2
1342Th1049Interferon beta-1aMSYNLLGFLQRSSNFQCQKL Full view166IbCancer/Infectious/ImmunologicalBetaferonBayerPowder and solvent that are made upto make solution.Subcutaneous InjectionImmunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2
1343Th1049Interferon beta-1aMSYNLLGFLQRSSNFQCQKL Full view166IbCancer/Infectious/ImmunologicalBetaseronMerckSterile, white to off-white powderSubcutaneous InjectionImmunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2
1345Th1049Interferon beta-1aMSYNLLGFLQRSSNFQCQKL Full view166IbCancer/Infectious/ImmunologicalExtaviaNovartisSterile, white to off-white powderSubcutaneous InjectionImmunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2
1368Th1054InfliximabN.A.
Full view
0IIaImmunologicalREMICADECentocor IncSterile, white, lyophilized powder, following reconstitution with 10 mL of Sterile Water for Injection, USP, the resulting pH is approximately 7.2.Intravenous infusionAntirheumatic Agents, Anti-Inflammatory Agents, Non-Steroidal, Dermatologic Agents, Gastrointestinal Agents and Immunosuppressive Agents Tumor necrosis factor
1376Th1057Interferon beta-1bMSYNLLGFLQRSSNFQSQKL Full view166IbImmunologicalBetaseronBayerSterile, white to off-white powderSubcutaneous InjectionAdjuvants, Immunologic and Immunosuppressive Agents N.A.
1377Th1057Interferon beta-1bMSYNLLGFLQRSSNFQSQKL Full view166IbImmunologicalBetaferonBayerPowder and solvent that are made upto make solution.Subcutaneous InjectionAdjuvants, Immunologic and Immunosuppressive Agents N.A.
1378Th1057Interferon beta-1bMSYNLLGFLQRSSNFQSQKL Full view166IbImmunologicalExtaviaNovartisSterile, white to off-white powderSubcutaneous InjectionAdjuvants, Immunologic and Immunosuppressive Agents N.A.
1385Th1061TrastuzumabLight chain 1: DIQMT Full view1364IIaCancerHerceptinGenentechSterile, white to pale yellow, preservative-free lyophilized powder Intravenous administrationAntineoplastic Agents Insulin receptor,Insulin-like growth factor 1 receptor,Insulin-degrading enzyme,HLA class II histocompatibility antigen, DQ alpha 2 chain,HLA class II histocompatibility antigen, DQ beta 1 chain,Retinoblastoma-associated protein,Cathepsin D,Carboxypeptidase E,Neuroendocrine convertase 2,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-related protein 2,Insulin-like growth factor-binding protein 7,Synaptotagmin-like protein 4
1403Th1065Digoxin Immune Fab (Ovine)Heavy Chain: EVQLQQS Full view438IIaCardiacDIGIBINDGalaxo Smith KlineSterile lyophilized powder of antigen binding fragments (Fab) derived from specific antidigoxin antibodies raised in sheep.Intravenous infusion after reconstitution with Sterile Water for InjectionAntidotes T-cell surface glycoprotein CD3 delta chain, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface glycoprotein CD3 gamma chain, T-cell surface glycoprotein CD3 zeta chain, Low affinity immunoglobulin gamma Fc region receptor III-B, Complement C1r subcomponent, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, Complement C1q subcomponent subunit C, Low affinity immunoglobulin gamma Fc region receptor III-A, Complement C1s subcomponent, High affinity immunoglobulin gamma Fc receptor I, Low affinity immunoglobulin gamma Fc region receptor II-a, Low affinity immunoglobulin gamma Fc region receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-c
1415Th1069PegvisomantFPTIPLSRLFDNAMLRAHRL Full view191IIaHormonalSOMAVERTPfizerSterile, white lyophilized powder Subcutaneous InjectionHormone Replacement Agents B-lymphocyte antigen CD20,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c
1421Th1070Botulinum Toxin Type AMPFVNKQFNYKDPVNGVDIA Full view1296IcNeurological DisorderXeominMERZ AESTHETICSSterile white to off-white lyophilized powder after reconstitution with preservative-free 0.9% Saline for Injection.Intramuscular InjectionNeuromuscular Blocking Agents, Anti-Wrinkle Agents and Antidystonic Agents Growth hormone receptor
1423Th1071PancrelipasePancreatic alpha amy Full view1206IaMetabolic/genetic/ViokaceAptalis Pharma US, Inc.Beige-white amorphous powder, miscible in water and practically insoluble in alcohol and converted to tablet formOral routeGastrointestinal Agents and Enzyme Replacement Agents Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch
1424Th1071PancrelipasePancreatic alpha amy Full view1206IaMetabolic/genetic/ULTRESAAptalis Pharma US, Inc.Beige-white amorphous powder, miscible in water and practically insoluble or insoluble in alcohol and ether and converted to Delayed-Release CapsulesOral routeGastrointestinal Agents and Enzyme Replacement Agents Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch