==== Reference: Usmani SS, Bedi G, Samuel JS, Singh S, Kalra S, Kumar P, et al. (2017) THPdb: Database of FDA-approved peptide and protein therapeutics. PLoS ONE 12(7) e0181748.====

Browse result page of THPdb

The total number entries retrieved from this search are 89
IDThPPIDNamePeptide SequenceLengthFunctional ClassificationDiseaseBrandCompanyPhysical AppearanceRoute of AdministartionCategoryTarget
1001Th1001LepirudinLVYTDCTESGQNLCLCEGSN Full view65IaHematological,MetabolicRefludanBerlex LabsSterile, white, freeze-dried powderIntravenous infusionAntithrombins and Fibrinolytic Agents Prothrombin
1022Th1003Dornase alfaLKIAAFNIQTFGETKMSNAT Full view255IbMetabolicPulmozymeGenentech IncN.A.Administered by inhalation of an aerosol mist produced by a compressed air driven nebulizer systemEnzymes DNA
1023Th1003Dornase alfaLKIAAFNIQTFGETKMSNAT Full view255IbMetabolicViscozymeRoche (Chile)N.A.Administered by inhalation of an aerosol mist produced by a compressed air driven nebulizer systemEnzymes DNA
1032Th1006BivalirudinFPRPGGGGNGDFEEIPEEYL Full view20IaHematological,MetabolicAngiomaxMedicines Co or MDCOWhite lyophilized cake in single-use vialsIntravenous infusionAntithrombins Prothrombin
1033Th1006BivalirudinFPRPGGGGNGDFEEIPEEYL Full view20IaHematological,MetabolicAngioxThe Medicines Company UK LtdPowder for concentrate for solutionInjectionAntithrombins Prothrombin
1055Th1009AlteplaseSYQVICRDEKTQMIYQQHQS Full view255IbHematological,MetabolicActivaseGenentech IncSterile, white to off-white, lyophilized powderIntravenousThrombolytic Agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1
1067Th1012ReteplaseSYQGNSDCYFGNGSAYRGTH Full view255IbHematological,MetabolicRetavaseCentocorSterile, white, lyophilized powderIntravenous InjectionFibrinolytic Agents, Thrombolytic agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1
1148Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicAdvateN.A.Powder formIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1149Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicAlphanateN.A.Lyophilized powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1150Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicBioclateBaxter Healthcare Corporation, Hyland Division and Genetics Institute, Inc.Sterile, nonpyrogenic, off-white to faint yellow, lyophilized powderIntravenous infusionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1151Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHelixate FSN.A.Sterile, stable, purified, nonpyrogenic, dried concentrateIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1152Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHemofil MN.A.Dry concentrateIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1153Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicHyate:CN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1154Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicKoate-HPN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1155Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicKogenate FSN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1156Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicMonarc-MN.A.PowderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1157Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicMonoclate-PN.A.Lyophilized powder for solutionIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1158Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicReFactoN.A.Lyophilized powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1159Th1022Antihemophilic FactorATRRYYLGAVELSWDYMQSD Full view255IaHematological,MetabolicXynthaN.A.Sterile, nonpyrogenic, preservative-free, freeze-dried powderIntravenous InjectionCoagulants and Thrombotic agents Coagulation factor X,Coagulation factor IX,von Willebrand factor,Phytanoyl-CoA dioxygenase, peroxisomal,Asialoglycoprotein receptor 2,78 kDa glucose-regulated protein,Calreticulin,Calnexin,Protein ERGIC-53,Prolow-density lipoprotein receptor-related protein 1,Multiple coagulation factor deficiency protein 2
1201Th1026AnistreplaseSYQVICRDEKTQMIYQQHQS Full view255IcHematological,MetabolicEminaseWulfing Pharma GmbHDry powderIntravenous infusionThrombolytic Agents, Fibrinolytic agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1
1210Th1028TenecteplaseSYQVICRDEKTQMIYQQHQS Full view255IbHematological,MetabolicTNKaseGenentech IncSterile, white to off-white, lyophilized powderIntravenous InjectionThrombolytic Agents, Fibrinolytic agents Plasminogen,Fibrinogen alpha chain,Urokinase plasminogen activator surface receptor,Plasminogen activator inhibitor 1,Plasminogen activator inhibitor 2,Tetranectin,Keratin, type II cytoskeletal 8,Annexin A2,Calreticulin,Calnexin,Prolow-density lipoprotein
1234Th1032Coagulation factor VIIaANAFLEELRPGSLERECKEE Full view255IbHematological,MetabolicNovoSevenNovo NordiskSterile, white lyophilized powderInjectionThrombotic Agents, Coagulants Coagulation factor X,Serine protease hepsin,Tissue factor pathway inhibitor,Vitamin K-dependent gamma-carboxylase,Coagulation factor VII,Tissue factor
1252Th1035Glucagon recombinantHSQGTFTSDYSKYLDSRRAQ Full view29IVHormonal/Metabolic/geneticGlucaGenNovo NordiskSterile, lyophilized white powderSubcutaneous, Intramuscular, or Intravenous infusionHypoglycemic Agents Glucagon receptor,Glucagon-like peptide 2 receptor,Glucagon-like peptide 1 receptor
1253Th1035Glucagon recombinantHSQGTFTSDYSKYLDSRRAQ Full view29IVHormonal/Metabolic/geneticGlucagonEli LillyPowderSubcutaneously or Intramuscularly InjectionHypoglycemic Agents Glucagon receptor,Glucagon-like peptide 2 receptor,Glucagon-like peptide 1 receptor
1275Th1040Insulin LisproA chain:GIVEQCCTSICS Full view51IaHormonal/Metabolic/geneticHumalogEli LillySterile, aqueous, clear, and colorless solutionSubcutaneous and Intravenous infusionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1276Th1040Insulin LisproA chain:GIVEQCCTSICS Full view51IaHormonal/Metabolic/geneticHumalog KwikPenEli LillySolutionSubcutaneous injectionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1277Th1040Insulin LisproA chain:GIVEQCCTSICS Full view51IaHormonal/Metabolic/geneticHumalog PenEli LillyN.A.N.A.Hypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1283Th1041Insulin GlargineA-chain:GIVEQCCTSICS Full view53IaHormonal/Metabolic/geneticLantusSanofi-AventisSolutionSubcutaneous injectionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1284Th1041Insulin GlargineA-chain:GIVEQCCTSICS Full view53IaHormonal/Metabolic/geneticLantus OptiSetN.A.SolutionSubcutaneous injectionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1285Th1041Insulin GlargineA-chain:GIVEQCCTSICS Full view53IaHormonal/Metabolic/geneticLantus SoloStarN.A.SolutionSubcutaneous injectionHypoglycemic Agents, Antidiabetic agents Insulin receptor,Insulin-like growth factor 1 receptor
1305Th1043RasburicaseSAVKAARYGKDNVRVYKVHK Full view255IcMetabolic/GeneticElitekSanofi-Synthelabo IncSterile, white to off-white, lyophilized powderIntravenous administrationAntihyperuricemic Agents, Gout suppressants Uric acid
1306Th1043RasburicaseSAVKAARYGKDNVRVYKVHK Full view255IcMetabolic/GeneticFasturtecN.A.Powder and solvent that are made upto make solution.Intravenous administartionAntihyperuricemic Agents, Gout suppressants Uric acid
1324Th1045ImigluceraseARPCIPKSFGYSSVVCVCNA Full view255IaMetabolicCerezymeGenzymeSterile, non-pyrogenic, white to off-white lyophilized productIntravenous infusionEnzyme Replacement Agents Glucocerebroside
1327Th1046AbciximabH ReoPro-like antibo Full view218IIaGenetic/Metabolic/HaemetologicalReoProEli Lilly and CompanyClear, colorless, sterile, non-pyrogenic solutionIntravenous administartionPlatelet Aggregation Inhibitors, Anticoagulants Integrin beta-3,Integrin alpha-IIb,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immuno
1331Th1047Alpha-1-proteinase inhibitorEDPQGDAAQKTDTSHHDQDH Full view255IIaMetabolic/Geneti/RespiratoryAralastBaxterLyophilized powderIntravenous infusionSerine Proteinase Inhibitors, Enzyme replacement agents, trypsin inhibitors Neutrophil elastase
1332Th1047Alpha-1-proteinase inhibitorEDPQGDAAQKTDTSHHDQDH Full view255IIaMetabolic/Geneti/RespiratoryProlastinTalecris Biotherapeutics C formerly BayerLyophilized powderIntravenous infusionSerine Proteinase Inhibitors, Enzyme replacement agents, trypsin inhibitors Neutrophil elastase
1358Th1050Pegademase bovineMAQTPAFNKPKVELHVHLDG Full view255IaMetabolicAdagenEnzon Inc.Isotonic, pyrogen free, sterile solution, pH 7.2-7.4Intramusular InjectionEnzyme Replacement Agents Adenosine,Growth factor receptor-bound protein 2
1361Th1051Human Serum AlbuminMKWVTFISLLFLFSSAYSRG Full view609IaHematological/Metabolic/geneticAlbuminarCSL BehringSterile aqueous solution of albumin obtained from large pools of adult human venous plasma by low temperature controlled fractionation according to the Cohn process.Albumin (Human) 25%, Albuminar-25 (albumin human) , is to be administered by the Intravenous route.Serum substitutes N.A.
1362Th1051Human Serum AlbuminMKWVTFISLLFLFSSAYSRG Full view609IaHematological/Metabolic/geneticAlbuteinGRIFOLSSterile, aqueous solution for single dose intravenous administration containing 20% human albumin (weight/volume).Albutein 20% is to be administered by the Intravenous route.Serum substitutes N.A.
1363Th1052EptifibatideMpr-Har-Gly-Asp-Trp- Full view7IbHematological/MetabolicINTEGRILINSchering-Plough/EssexClear, colorless, sterile, non-pyrogenic solution  of EptifibatideInjection Solution for IIntravenousUsePlatelet Aggregation Inhibitors Lutropin-choriogonadotropic hormone receptor,Follicle-stimulating hormone receptor
1382Th1060Insulin, porcineA chain: GIVEQCCTSIC Full view51IaHormonal/MetabolicvetsulinIntervet Inc (Merck Animal Health)Sterile injectable suspension in multidose vials containing 10 mL of 40 IU/mL porcine insulin zinc suspensionSubcutaneous InjectionHypoglycemic Agents Interferon alpha/beta receptor 2,Interferon alpha/beta receptor 1, Hyaluronan, Transforming growth factor beta-1
1422Th1071PancrelipasePancreatic alpha amy Full view1206IaMetabolic/genetic/PancrecarbDigestive care US, Inc.Delayed-Release Capsules, Buffered and Enteric-Coated Microspheres.Oral routeGastrointestinal Agents and Enzyme Replacement Agents Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch
1423Th1071PancrelipasePancreatic alpha amy Full view1206IaMetabolic/genetic/ViokaceAptalis Pharma US, Inc.Beige-white amorphous powder, miscible in water and practically insoluble in alcohol and converted to tablet formOral routeGastrointestinal Agents and Enzyme Replacement Agents Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch
1424Th1071PancrelipasePancreatic alpha amy Full view1206IaMetabolic/genetic/ULTRESAAptalis Pharma US, Inc.Beige-white amorphous powder, miscible in water and practically insoluble or insoluble in alcohol and ether and converted to Delayed-Release CapsulesOral routeGastrointestinal Agents and Enzyme Replacement Agents Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch
1425Th1071PancrelipasePancreatic alpha amy Full view1206IaMetabolic/genetic/PERTZYEDigestive care US, Inc.Beige-white amorphous powder, miscible in water and practically insoluble or insoluble in alcohol and ether PERTZYE delayed-release capsuleOral routeGastrointestinal Agents and Enzyme Replacement Agents Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch
1426Th1071PancrelipasePancreatic alpha amy Full view1206IaMetabolic/genetic/ULTRASEAxcan PharmaCapsules Enteric-Coated MicrospheresOral routeGastrointestinal Agents and Enzyme Replacement Agents Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch
1427Th1071PancrelipasePancreatic alpha amy Full view1206IaMetabolic/genetic/ZENPEPAptalis Pharma US, Inc.Delayed-Release CapsulesOral routeGastrointestinal Agents and Enzyme Replacement Agents Synaptosomal-associated protein 25,Rho-related GTP-binding protein RhoB, Dietary fat,Dietary protein,Dietary starch
1428Th1072StreptokinaseMKNYLSFGMFALLFALTFGT Full view440IcMetabolic/HaemetologicalStreptaseCSL BehringSterile, purified preparation formulated as lypholized powderIntravenous and intracoronary administration.Fibrinolytic Agents and Thrombolytic Agents N.A.
1434Th1074AlgluceraseARPCIPKSFGYSSVVCVCNA Full view497IaMetabolicCeredaseGenzyme CorporationClear sterile non-pyrogenic solution of alglucerase in a citrate buffered solutionIntravenous injectionEnzyme Replacement Agents Plasminogen,Proteinase-activated receptor 1
1437Th1076LaronidaseAPHLVQVDAARALWPLRRFW Full view626IaMetabolicALDURAZYMEGenzyme CorporationSterile, nonpyrogenic, colorless to pale yellow, clear to slightly opalescent solution that must be diluted prior to administration in 0.9% Sodium Chloride InjectionIntravenous infusionEnzyme Replacement Agents N.A.