==== Reference: Usmani SS, Bedi G, Samuel JS, Singh S, Kalra S, Kumar P, et al. (2017) THPdb: Database of FDA-approved peptide and protein therapeutics. PLoS ONE 12(7) e0181748.====

Browse result page of THPdb

The total number entries retrieved from this search are 44
IDThPPIDNamePeptide SequenceLengthFunctional ClassificationDiseaseBrandCompanyPhysical AppearanceRoute of AdministartionCategoryTarget
1005Th1002CetuximabHeavy chain:QVQLKQSG Full view243IIIcCancerErbituxImClone Systems IncSterile, clear, colorless liquid of pH 7.0-7.4, which may contain a small amount of easily visible, white, amorphous cetuximab particulatesIntravenous infusionAntineoplastic Agents Epidermal growth factor receptor,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,Complement C1s subcomponent,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c
1025Th1004Denileukin diftitoxMGADDVVDSSKSFVMENFSS Full view255IIbCancerOntakSeragen IncSterile, white, preservative-free, lyophilized powder.Intravenous(IV) administrationAntineoplastic Agents Interleukin-2 receptor subunit alpha,Interleukin-2 receptor subunit beta,Cytokine receptor common subunit gamma
1038Th1007LeuprolidePHWSYLLR
Full view
8IIaCancerEligardAtrix Labs/QLT InSuspensionSubcutaneous InjectionAntineoplastic Agents, Hormonal and fertility agents, estrogen antagonists Gonadotropin-releasing hormone receptor
1039Th1007LeuprolidePHWSYLLR
Full view
8IIaCancerEnantoneTakedaSolutionInjectionAntineoplastic Agents, Hormonal and fertility agents, estrogen antagonists Gonadotropin-releasing hormone receptor
1040Th1007LeuprolidePHWSYLLR
Full view
8IIaCancerLeuplinTakedaN.A.InjectionAntineoplastic Agents, Hormonal and fertility agents, estrogen antagonists Gonadotropin-releasing hormone receptor
1041Th1007LeuprolidePHWSYLLR
Full view
8IIaCancerLeuProMaxxBaxter/TevaN.A.N.A.Antineoplastic Agents, Hormonal and fertility agents, estrogen antagonists Gonadotropin-releasing hormone receptor
1042Th1007LeuprolidePHWSYLLR
Full view
8IIaCancerLeupromerN.A.N.A.InjectionAntineoplastic Agents, Hormonal and fertility agents, estrogen antagonists Gonadotropin-releasing hormone receptor
1043Th1007LeuprolidePHWSYLLR
Full view
8IIaCancerLupronAbbott/TAP PharmaceuticalsN.A.InjectionAntineoplastic Agents, Hormonal and fertility agents, estrogen antagonists Gonadotropin-releasing hormone receptor
1044Th1007LeuprolidePHWSYLLR
Full view
8IIaCancerLutrateN.A.N.A.N.A.Antineoplastic Agents, Hormonal and fertility agents, estrogen antagonists Gonadotropin-releasing hormone receptor
1045Th1007LeuprolidePHWSYLLR
Full view
8IIaCancerMemryteCuraxisN.A.N.A.Antineoplastic Agents, Hormonal and fertility agents, estrogen antagonists Gonadotropin-releasing hormone receptor
1046Th1007LeuprolidePHWSYLLR
Full view
8IIaCancerProstap 3Takeda UK LimitedN.A.N.A.Antineoplastic Agents, Hormonal and fertility agents, estrogen antagonists Gonadotropin-releasing hormone receptor
1047Th1007LeuprolidePHWSYLLR
Full view
8IIaCancerProstap SRTakeda UK LimitedN.A.N.A.Antineoplastic Agents, Hormonal and fertility agents, estrogen antagonists Gonadotropin-releasing hormone receptor
1048Th1007LeuprolidePHWSYLLR
Full view
8IIaCancerViadurBayer AGN.A.N.A.Antineoplastic Agents, Hormonal and fertility agents, estrogen antagonists Gonadotropin-releasing hormone receptor
1142Th1020AsparaginaseQMSLQQELRYIEALSAIVET Full view255IcCancerElsparMerck & Co. IncLyophilized plug or powderIntravenous or Intramuscular. Intravenous method dose has higher risk of allergic reaction, so often a test dose is given first.Antineoplastic Agents L-asparagine
1257Th1036AldesleukinMAPTSSSTKKTQLQLEHLLL Full view134IbCancer/InfectiousProleukinChiron CorpSterile, white to off-white, lyophilized cakeIntravenous administrationAntineoplastic Agents, Anti-HIV agents Interleukin-2 receptor subunit beta,Interleukin-2 receptor subunit alpha,Cytokine receptor common subunit gamma
1337Th1048PegaspargaseMEFFKKTALAALVMGFSGAA Full view255IcCancerOncasparEnzon IncSolutionIntravenous or Intramuscular administrationAntineoplastic Agents L-asparagine
1341Th1049Interferon beta-1aMSYNLLGFLQRSSNFQCQKL Full view166IbCancer/Infectious/ImmunologicalAvonexBiogen IncLyophilized powder vial, Sterile liquid as single used prefilled syringe and also available as single use prefilled autoinjector.Intramuscular InjectionImmunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2
1342Th1049Interferon beta-1aMSYNLLGFLQRSSNFQCQKL Full view166IbCancer/Infectious/ImmunologicalBetaferonBayerPowder and solvent that are made upto make solution.Subcutaneous InjectionImmunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2
1343Th1049Interferon beta-1aMSYNLLGFLQRSSNFQCQKL Full view166IbCancer/Infectious/ImmunologicalBetaseronMerckSterile, white to off-white powderSubcutaneous InjectionImmunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2
1344Th1049Interferon beta-1aMSYNLLGFLQRSSNFQCQKL Full view166IbCancer/Infectious/ImmunologicalBlastoferonSidusN.A.N.A.Immunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2
1345Th1049Interferon beta-1aMSYNLLGFLQRSSNFQCQKL Full view166IbCancer/Infectious/ImmunologicalExtaviaNovartisSterile, white to off-white powderSubcutaneous InjectionImmunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2
1346Th1049Interferon beta-1aMSYNLLGFLQRSSNFQCQKL Full view166IbCancer/Infectious/ImmunologicalRebifMerckSterile solution in a prefilled syringe or REBIF Rebidose autoinjectorSubcutaneous InjectionImmunosuppressive Agents, Antineoplastic, Antiviral, Immunologic factors Interferon alpha/beta receptor 1,Interferon alpha/beta receptor 2
1385Th1061TrastuzumabLight chain 1: DIQMT Full view1364IIaCancerHerceptinGenentechSterile, white to pale yellow, preservative-free lyophilized powder Intravenous administrationAntineoplastic Agents Insulin receptor,Insulin-like growth factor 1 receptor,Insulin-degrading enzyme,HLA class II histocompatibility antigen, DQ alpha 2 chain,HLA class II histocompatibility antigen, DQ beta 1 chain,Retinoblastoma-associated protein,Cathepsin D,Carboxypeptidase E,Neuroendocrine convertase 2,Neuroendocrine convertase 1,Protein NOV homolog,Low-density lipoprotein receptor-related protein 2,Insulin-like growth factor-binding protein 7,Synaptotagmin-like protein 4
1389Th1062RituximabHeavy Chain: QVQLQQP Full view664IIaCancer/ImmunologicalRituxanBiogen Idec Inc., and Genentech USA, IncSterile, clear, colorless, preservative-free liquid concentrate Intravenous administrationAntineoplastic Agents, Immunologic Factors and Antirheumatic Agents B-lymphocyte antigen CD20,Low affinity immunoglobulin gamma Fc region receptor III-B,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Low affinity immunoglobulin gamma Fc region receptor III-A,Complement C1s subcomponent,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor II-c, Receptor tyrosine-protein kinase erbB-2,Epidermal growth factor receptor,Complement C1r subcomponent,Complement C1q subcomponent subunit A,Complement C1q subcomponent subunit B,Complement C1q subcomponent subunit C,Complement C1s subcomponent,High affinity immunoglobulin gamma Fc receptor I,Low affinity immunoglobulin gamma Fc region receptor II-a,Low affinity immunoglobulin gamma Fc region receptor II-b,Low affinity immunoglobulin gamma Fc region receptor I
1548Th1117IpilimumabHeavy chain: QVQLVES Full view663IIIcCancerYERVOYBristol-Myers SquibbSterile, preservative-free, clear to slightly opalescent, colorless to pale-yellow solutionN.A.Antineoplastic Agents and Monoclonal antibodies Cytotoxic T-lymphocyte protein 4
1615Th1133AfliberceptSDTGRPFVEMYSEIPEIIHM Full view431IbCancerEyleaRegeneron PharmaceuticalsSterile, clear, and colorless to pale yellow solution.Intravitreal injectionAntineoplastic Agents and Ophthalmics Vascular endothelial growth factor A,Placenta growth factor,Vascular endothelial growth factor B
1616Th1133AfliberceptSDTGRPFVEMYSEIPEIIHM Full view431IbCancerZaltrapSanofi and Regeneron Pharmaceuticals, Inc.Sterile, clear, colorless to pale yellow, non-pyrogenic, preservative-free, solution.Intravenous infusionAntineoplastic Agents and Ophthalmics Vascular endothelial growth factor A,Placenta growth factor,Vascular endothelial growth factor B
1636Th1142ObinutuzumabN.A. Full view0IIbCancerGazyvaGenentechSterile, clear, colorless to slightly brown, preservative free liquid concentrateIntravenous infusionAntineoplastic Agents B-lymphocyte antigen CD20
1671Th1159Gemtuzumab ozogamicinLight Chain 1: QIVLT Full view459IIbCancerMylotargWyeth pharmaceuticals incSterile, white, preservative-free lyophilized powderIntravenous infusionAntineoplastic agents and Immunotoxins Myeloid cell surface antigen CD33, Low affinity immunoglobulin gamma Fc region receptor III-B, Complement C1r subcomponent, Complement C1q subcomponent subunit A, Complement C1q subcomponent subunit B, Complement C1q subcomponent subunit C, Low affinity immunoglobulin gamma Fc region receptor III-A, Complement C1s subcomponent, High affinity immunoglobulin gamma Fc receptor I, Low affinity immunoglobulin gamma Fc region receptor II-a, Low affinity immunoglobulin gamma Fc region receptor II-b, Low affinity immunoglobulin gamma Fc region receptor II-c
1708Th1170BlinatumomabDIQLTQSPASLAVSLGQRAT Full view504IIIcCancer/GeneticBlincytoAMGENLyophilized Powder for intravenous administrationIntravenousAntineoplastic Agents, Immunosuppressive Agents, Monoclonal antibodies, Antineoplastic and Immunomodulating Agents B-lymphocyte antigen CD19; T-cell surface glycoprotein CD3 delta chain
1724Th1174DaratumumabNA Full view0IIIcCancerDarzalexJanssen Biotech, Inc.Solution, concentrateIntravenousAntineoplastic Agents ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1
1797Th1191VedolizumabHeavy Chain Sequence Full view716IIaImmunological DisordersEntyvioTakeda Pharmaceuticals America, Inc.Injection, Powder, Lyophilized, for SolutionIntravenousImmunosupressive agent, Antineoplastic agent Integrin alpha-4, Integrin beta-7
1798Th1192UstekinumabNA Full view0IIIbInfectious DiseaseStelaraJanssen Biotech, Inc.Solution fro InjectionSubcutaneousDeramtologic agent, Immunosuppressive agent, antineoplastic agent Interleukin-12 subunit beta
1802Th1196SiltuximabHeavy Chain Sequence Full view708IIaImmunological DisordersSylvantJanssen IncLyophilized PowderIntravenous infusionAntineoplastic and Immunomodulating Agents, Immunosuppressive Agents Interleukin-6
1805Th1199Ramucirumabramucirumab|Homo sap Full view909IIIcCancerCyramzaEli Lilly and CompanySolutionIntravenousAntineoplastic and Immunomodulating Agents Vascular endothelial growth factor receptor 2
1811Th1202PembrolizumabHeavy Chain Sequence Full view711IIIcCancerKeytrudaMerck Sharp & Dohme Corp.Lyophilized PowderIntravenous infusionAntineoplastic and Immunomodulating Agents Programmed cell death protein 1
1813Th1204OfatumumabOfatumumab Heavy Cha Full view483IIIcCancerArzerraGlaxo Smith Kline LlcLiquidIntravenousAntineoplastic and Immunomodulating Agents
1815Th1206NivolumabHeavy Chain Sequence Full view710IIIcCancerOpdivoE.R. Squibb & Sons, L.L.C.LiquidIntravenousAntineoplastic and Immunomodulating Agents Programmed cell death protein 1
1819Th1210MepolizumabNA Full view0IbRespiratory DisorderNucalaGlaxosmithkline IncLyophilized PowderSubcutaneousAntineoplastic and Immunomodulating Agents, Immunosuppressive Agents, Interleukin Inhibitors Interleukin-5
1830Th1220BrodalumabNA Full view0IIaImmunological DisordersSiliqNAsterile, preservative-free, clear to slightly opalescent, colorless to slightly yellow solutionSubcutaneousAntineoplastic and Immunomodulating Agents Interleukin 17 receptor A
1832Th1222Canakinumab H-GAMMA-1 Chain: QVQ Full view842IIaImmunological DisordersIlarisNovartisLyphilized powderSubcutaneousAntineoplastic and Immunomodulating Agents Interleukin-1 beta
1837Th1226DinutuximabNA Full view0IIIcCancerunituxinNAsterile, preservative-free, clear/colorless to slightly opalescent solution Intravenous Antibody, Immunosuppresive agent, Antineoplastic agent Ganglioside GD2 (small molecule)
1844Th1232LenograstimNA Full view0IbImmunological DisordersGranocyteNASolidSubcutaneous or IntravenousAntineoplastic and Immunomodulating Agents Granulocyte colony-stimulating factor receptor
1848Th1236Sipuleucel-TNA Full view0IIIcCancerProvengeNASolutionIntravenousAntineoplastic and Immunomodulating Agents Prostatic acid phosphatase