Browse result page of PRRDB 2.0

PRRID	Name of Ligand	Source of ligand	Sequence of Ligand	Length of Ligand	Type of Ligand	Occurence	Role of Ligand	Name of Receptor	Type of Reeptor	Source of the Receptor	Localization	Domain	Sequence of Receptor	Swiss prot ID	Length of receptor	Function of Receptor	Assay used	PMID	Year of publication	Pubchem assay
PRRID_0025	Mannan Click for more detail	Fungi	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Immunostimulant	Mannose receptor	Mannose receptor (MR)	NA	NA	NA	NA	NA	NA	NA	ELISA	8416946	1993	NA
PRRID_0025	Mannan Click for more detail	Fungi	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Immunostimulant	Mannose receptor	Mannose receptor (MR)	NA	NA	NA	NA	NA	NA	NA	ELISA	8416946	1993	NA
PRRID_0134	Mannan Click for more detail	S. cerevisiae (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Monocytes	NA	O00206.fasta	O00206	839	This leads to the inflammatory response.	ELISA	12222939	2002	Pubchem Assay
PRRID_0134	Mannan Click for more detail	S. cerevisiae (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Monocytes	NA	O00206.fasta	O00206	839	This leads to the inflammatory response.	ELISA	12222939	2002	Pubchem Assay
PRRID_0135	Mannan Click for more detail	Candida albicans(fungi)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Monocytes	NA	O00206.fasta	O00206	839	This is responsible for the anti-fungal response of the host immune system.	ELISA	12222939	2002	Pubchem Assay
PRRID_0135	Mannan Click for more detail	Candida albicans(fungi)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Monocytes	NA	O00206.fasta	O00206	839	This is responsible for the anti-fungal response of the host immune system.	ELISA	12222939	2002	Pubchem Assay
PRRID_0136	Mannan Click for more detail	S. cerevisiae (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Monocytes	NA	O00206.fasta	O00206	839	This leads to the inflammatory response.	ELISA	12222939	2002	Pubchem Assay
PRRID_0136	Mannan Click for more detail	S. cerevisiae (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Monocytes	NA	O00206.fasta	O00206	839	This leads to the inflammatory response.	ELISA	12222939	2002	Pubchem Assay
PRRID_0137	Mannan Click for more detail	Candida albicans(fungi)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Monocytes	NA	O00206.fasta	O00206	839	This is responsible for the anti-fungal response of the host immune system.	ELISA	12222939	2002	Pubchem Assay
PRRID_0137	Mannan Click for more detail	Candida albicans(fungi)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Stimulation with mannan leads to the induction of TNF-alpha, which leads to the ptoduction of the proinflammatory cytokines.	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Monocytes	NA	O00206.fasta	O00206	839	This is responsible for the anti-fungal response of the host immune system.	ELISA	12222939	2002	Pubchem Assay
PRRID_0671	Mannan Click for more detail	Candida albicans(fungi)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	NA	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Mice (Murine)	dendritic cells and macrophages	Leucine-rich Repeat (LRR) Domain	Q9QUK6.fasta	Q9QUK6	835	NA	NA	20713100	2010	Pubchem Assay
PRRID_0671	Mannan Click for more detail	Candida albicans(fungi)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	NA	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Mice (Murine)	dendritic cells and macrophages	Leucine-rich Repeat (LRR) Domain	Q9QUK6.fasta	Q9QUK6	835	NA	NA	20713100	2010	Pubchem Assay
PRRID_0672	Mannan Click for more detail	Candida albicans(fungi)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,TIRAP, TRAM and TRIF	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Cell surface	Leucine-rich Repeat (LRR) Domain	O00206.fasta	O00206	839	It leadsto the secretion of the proinfalmmatory cytokines and IFN-Œ≤	NA	20620129	2010	Pubchem Assay
PRRID_0672	Mannan Click for more detail	Candida albicans(fungi)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Upon recogniton by the TLR, it induces induces the recruitment of adaptor proteins MyD88,TIRAP, TRAM and TRIF	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	Cell surface	Leucine-rich Repeat (LRR) Domain	O00206.fasta	O00206	839	It leadsto the secretion of the proinfalmmatory cytokines and IFN-Œ≤	NA	20620129	2010	Pubchem Assay
PRRID_0673	Mannan Click for more detail	Bacteria	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	It is the responsive PAMP for the FcLec5	FcLec5	C type Lectin (CTL/CLR)	Fenneropenaeus chinensis	hepatopancreas	CRD	NA	NA	NA	It elicit the immune response, which leads to the clearance of bacteria	ELISA	20349323	2010	NA
PRRID_0673	Mannan Click for more detail	Bacteria	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	It is the responsive PAMP for the FcLec5	FcLec5	C type Lectin (CTL/CLR)	Fenneropenaeus chinensis	hepatopancreas	CRD	NA	NA	NA	It elicit the immune response, which leads to the clearance of bacteria	ELISA	20349323	2010	NA
PRRID_1106	Mannan Click for more detail	S. cerevisiae (Bacteria)	C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)O)CO)CO)CO)O)O)O)O	NA	Polysaccharides	Natural	PPL is a glycoprotein with a mannan-binding specificity and elicits the downstream cascade.	Philyra pisum lectin (PPL)	Mannose receptor (MR)	Philyra pisum	NA	NA	NA	NA	NA	It has antiproliferative effects on human cancer cells	Hemagglutination inhibition assay	24381505	2013	NA
PRRID_1106	Mannan Click for more detail	S. cerevisiae (Bacteria)	C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)O)CO)CO)CO)O)O)O)O	NA	Polysaccharides	Natural	PPL is a glycoprotein with a mannan-binding specificity and elicits the downstream cascade.	Philyra pisum lectin (PPL)	Mannose receptor (MR)	Philyra pisum	NA	NA	NA	NA	NA	It has antiproliferative effects on human cancer cells	Hemagglutination inhibition assay	24381505	2013	NA
PRRID_1482	Mannan Click for more detail	Fungi(Yeast)	N[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=O	NA	Polysaccharides	Natural	cell wall polysaccharide found in yeasts.	Mannose receptor	Mannose receptor (MR)	European and African Children	DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin)	NA	A5D8T8.fasta	A5D8T8	446	Phagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammation	ELISA	24743542	2014	Pubchem_assay
PRRID_1482	Mannan Click for more detail	Fungi(Yeast)	N[C@@H](CCC[C@@H](NC(=O)CC[C@@H](N)C(O)=O)C(O)=O)C(O)=O	NA	Polysaccharides	Natural	cell wall polysaccharide found in yeasts.	Mannose receptor	Mannose receptor (MR)	European and African Children	DC-SIGN (dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin)	NA	A5D8T8.fasta	A5D8T8	446	Phagocytosis of pathogens, Antigen presentation, Intracellular signalling, Resolution of inflammation	ELISA	24743542	2014	Pubchem_assay
PRRID_1785	Mannan Click for more detail	Gram-negative bacteria Escherichia coli, Vibrio anguillarum	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Bacterial infection and immunostimulant	CgPGRPS2	Peptidoglycan Recognition Receptor (PGRPs)	Crassostrea gigas	Cytoplasm	one typical PGRP/amidase domain	NA	NA	NA	Activate NF-kB	PAMPs binding assay	28042081	2016	NA
PRRID_1785	Mannan Click for more detail	Gram-negative bacteria Escherichia coli, Vibrio anguillarum	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Bacterial infection and immunostimulant	CgPGRPS2	Peptidoglycan Recognition Receptor (PGRPs)	Crassostrea gigas	Cytoplasm	one typical PGRP/amidase domain	NA	NA	NA	Activate NF-kB	PAMPs binding assay	28042081	2016	NA
PRRID_1788	Mannan Click for more detail	Gram positive bacteria, Staphylococcus aureus and fungi Yarrowia lipolytica (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Bacterial infection and immunostimulant	CgPGRPS2	Peptidoglycan Recognition Receptor (PGRPs)	Crassostrea gigas	Cytoplasm	one typical PGRP/amidase domain	NA	NA	NA	Activate NF-kB	PAMPs binding assay	28042081	2016	NA
PRRID_1788	Mannan Click for more detail	Gram positive bacteria, Staphylococcus aureus and fungi Yarrowia lipolytica (Bacteria)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Bacterial infection and immunostimulant	CgPGRPS2	Peptidoglycan Recognition Receptor (PGRPs)	Crassostrea gigas	Cytoplasm	one typical PGRP/amidase domain	NA	NA	NA	Activate NF-kB	PAMPs binding assay	28042081	2016	NA
PRRID_1801	Mannan Click for more detail	S. cerevisiae (Bacteria)	C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)O)CO)CO)CO)O)O)O)O	NA	Polysaccharides	Natural	Immunostimulant	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	Activate NF-Kb	NA	27293318	2016	NA
PRRID_1801	Mannan Click for more detail	S. cerevisiae (Bacteria)	C(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)OC4C(OC(C(C4O)O)O)CO)CO)CO)O)O)O)O	NA	Polysaccharides	Natural	Immunostimulant	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	NA	NA	NA	NA	NA	NA	Activate NF-Kb	NA	27293318	2016	NA
PRRID_2303	Mannan Click for more detail	Bacteria	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	NA	rCgPGRPS2	Pattern recognition receptor (PRR)	NA	NA	NA	NA	NA	NA	NA	NA	28042081	2017	NA
PRRID_2303	Mannan Click for more detail	Bacteria	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	NA	rCgPGRPS2	Pattern recognition receptor (PRR)	NA	NA	NA	NA	NA	NA	NA	NA	28042081	2017	NA
PRRID_2323	Mannan Click for more detail	Fungi(Yeast)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Activate macrophages and produce inflammatory responses, Induce NF-Œ∫B activation, induce PGE2Ôò∫, IL-1ÔõúŒ≤, and TNF-Œ± production, by macrophages	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Mice	NA	Leucine-rich Repeat (LRR) Domain	Q9QUK6.fasta	Q9QUK6	835	NA	NA	29028369	2017	Pubchem_assay
PRRID_2323	Mannan Click for more detail	Fungi(Yeast)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Activate macrophages and produce inflammatory responses, Induce NF-Œ∫B activation, induce PGE2Ôò∫, IL-1ÔõúŒ≤, and TNF-Œ± production, by macrophages	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Mice	NA	Leucine-rich Repeat (LRR) Domain	Q9QUK6.fasta	Q9QUK6	835	NA	NA	29028369	2017	Pubchem_assay
PRRID_2324	Mannan Click for more detail	Fungi(Yeast)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Activate macrophages and produce inflammatory responses, Induce NF-Œ∫B activation, induce PGE2Ôò∫, IL-1ÔõúŒ≤, and TNF-Œ± production, by macrophages	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	O00206.fasta	O00206	839	NA	NA	29028369	2017	Pubchem_assay
PRRID_2324	Mannan Click for more detail	Fungi(Yeast)	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Polysaccharides	Natural	Activate macrophages and produce inflammatory responses, Induce NF-Œ∫B activation, induce PGE2Ôò∫, IL-1ÔõúŒ≤, and TNF-Œ± production, by macrophages	Toll-like receptor 4 (TLR4)	Toll-like receptor (TLR)	Human	NA	Leucine-rich Repeat (LRR) Domain	O00206.fasta	O00206	839	NA	NA	29028369	2017	Pubchem_assay