Browse result page of PRRDB 2.0

PRRID	Name of Ligand	Source of ligand	Sequence of Ligand	Length of Ligand	Type of Ligand	Occurence	Role of Ligand	Name of Receptor	Type of Reeptor	Source of the Receptor	Localization	Domain	Sequence of Receptor	Swiss prot ID	Length of receptor	Function of Receptor	Assay used	PMID	Year of publication	Pubchem assay
PRRID_0005	Fucoidan Click for more detail	NA	CC1C(C(C(C(O1)C)OS(=O)(=O)O)O)O	NA	Carbohydrate	Natural	elicit innate immune response	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	Bovine	smooth muscle cells	NA	NA	NA	NA	NA	NA	3397384	1988	NA
PRRID_0005	Fucoidan Click for more detail	NA	CC1C(C(C(C(O1)C)OS(=O)(=O)O)O)O	NA	Carbohydrate	Natural	elicit innate immune response	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	Bovine	smooth muscle cells	NA	NA	NA	NA	NA	NA	3397384	1988	NA
PRRID_0009	Acetylated LDL Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Immunostimulant	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	NA	2300204	1991	NA
PRRID_0009	Acetylated LDL Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Immunostimulant	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	NA	2300204	1991	NA
PRRID_0010	Advanced Glycation End Products (AGE) Click for more detail	Endogenous (others)	NA	NA	Lipoprotein	Natural	Immunostimulant	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	NA	2300204	1991	NA
PRRID_0010	Advanced Glycation End Products (AGE) Click for more detail	Endogenous (others)	NA	NA	Lipoprotein	Natural	Immunostimulant	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	NA	2300204	1991	NA
PRRID_0012	Fucoidan Click for more detail	NA	CC1C(C(C(C(O1)C)OS(=O)(=O)O)O)O	NA	Carbohydrate	Natural	It Stimulates the secretion of urokinasetype plasminogen activator (uPA) in Protein Kinase-C (PKC) dependent manner.	Scavenger receptor class A	Scavenger receptor (SR)	Macrophage cell line (RAW264)	Macrophages	NA	NA	NA	NA	It leads to polyanion-induced macrophage plasminogen activation.	Functional assay for plasmin	1658006	1991	NA
PRRID_0012	Fucoidan Click for more detail	NA	CC1C(C(C(C(O1)C)OS(=O)(=O)O)O)O	NA	Carbohydrate	Natural	It Stimulates the secretion of urokinasetype plasminogen activator (uPA) in Protein Kinase-C (PKC) dependent manner.	Scavenger receptor class A	Scavenger receptor (SR)	Macrophage cell line (RAW264)	Macrophages	NA	NA	NA	NA	It leads to polyanion-induced macrophage plasminogen activation.	Functional assay for plasmin	1658006	1991	NA
PRRID_0015	oxidized LDL (OxLDL) Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Immunostimulant	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	NA	2300204	1991	NA
PRRID_0015	oxidized LDL (OxLDL) Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Immunostimulant	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	NA	2300204	1991	NA
PRRID_0016	Phorbol myristate acetate (PMA) Click for more detail	NA	CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C	NA	Carbohydrate	Natural	It Stimulates the secretion of urokinasetype plasminogen activator (uPA) in Protein Kinase-C (PKC) dependent manner.	Scavenger receptor class A	Scavenger receptor (SR)	Macrophage cell line (RAW264)	Macrophages	NA	NA	NA	NA	It leads to polyanion-induced macrophage plasminogen activation.	Functional assay for plasmin	1658006	1991	NA
PRRID_0016	Phorbol myristate acetate (PMA) Click for more detail	NA	CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C	NA	Carbohydrate	Natural	It Stimulates the secretion of urokinasetype plasminogen activator (uPA) in Protein Kinase-C (PKC) dependent manner.	Scavenger receptor class A	Scavenger receptor (SR)	Macrophage cell line (RAW264)	Macrophages	NA	NA	NA	NA	It leads to polyanion-induced macrophage plasminogen activation.	Functional assay for plasmin	1658006	1991	NA
PRRID_0019	Asbestos Click for more detail	Crocidolite(others)	O.O[Si]([O-])([O-])[O-].O[Si]([O-])([O-])[O-].[Mg+2].[Mg+2].[Mg+2]	NA	Silicate Mineral	Natural	Crocidolite Asbestos specfically binds to secreted extracellular domains of macrophage scavenger receptor.	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	Chinese Hamster	ovary cells	NA	NA	NA	NA	It mediates the physiological and pathological interactions of the particles with alveolar macrophages.	Solid-phase bead-binding assay	8381434	1992	NA
PRRID_0019	Asbestos Click for more detail	Crocidolite(others)	O.O[Si]([O-])([O-])[O-].O[Si]([O-])([O-])[O-].[Mg+2].[Mg+2].[Mg+2]	NA	Silicate Mineral	Natural	Crocidolite Asbestos specfically binds to secreted extracellular domains of macrophage scavenger receptor.	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	Chinese Hamster	ovary cells	NA	NA	NA	NA	It mediates the physiological and pathological interactions of the particles with alveolar macrophages.	Solid-phase bead-binding assay	8381434	1992	NA
PRRID_0020	Asbestos Click for more detail	Crocidolite(others)	O.O[Si]([O-])([O-])[O-].O[Si]([O-])([O-])[O-].[Mg+2].[Mg+2].[Mg+2]	NA	Silicate Mineral	Natural	Crocidolite Asbestos specfically binds to secreted extracellular domains of macrophage scavenger receptor.	Scavenger receptor A II	Scavenger receptor (SR)	Chinese Hamster	ovary cells	NA	NA	NA	NA	It mediates the physiological and pathological interactions of the particles with alveolar macrophages.	Solid-phase bead-binding assay	8381434	1992	NA
PRRID_0020	Asbestos Click for more detail	Crocidolite(others)	O.O[Si]([O-])([O-])[O-].O[Si]([O-])([O-])[O-].[Mg+2].[Mg+2].[Mg+2]	NA	Silicate Mineral	Natural	Crocidolite Asbestos specfically binds to secreted extracellular domains of macrophage scavenger receptor.	Scavenger receptor A II	Scavenger receptor (SR)	Chinese Hamster	ovary cells	NA	NA	NA	NA	It mediates the physiological and pathological interactions of the particles with alveolar macrophages.	Solid-phase bead-binding assay	8381434	1992	NA
PRRID_0027	poly(I:G) Click for more detail	synthetic oligonucleotide (others)	C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O	NA	Nucleic Acid	Synthetic	Immunostimulant	Scavenger receptor A II	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	ELISA	8429030	1993	NA
PRRID_0027	poly(I:G) Click for more detail	synthetic oligonucleotide (others)	C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O	NA	Nucleic Acid	Synthetic	Immunostimulant	Scavenger receptor A II	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	ELISA	8429030	1993	NA
PRRID_0028	poly(I:G) Click for more detail	synthetic oligonucleotide (others)	C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O	NA	Nucleic Acid	Synthetic	Immunostimulant	Scavenger receptor A II	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	ELISA	8429030	1993	NA
PRRID_0028	poly(I:G) Click for more detail	synthetic oligonucleotide (others)	C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)(O)O)O)O.C1=NC(=O)C2=C(N1)N(C=N2)C3C(C(C(O3)COP(=O)(O)O)O)O	NA	Nucleic Acid	Synthetic	Immunostimulant	Scavenger receptor A II	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	ELISA	8429030	1993	NA
PRRID_0031	maleylated BSA Click for more detail	NA	MKWVTFISLLLLFSSAYSRGVFRRDTHKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA	607	Protein	Natural	Immunostimulant	Scavenger receptor B-1 (SR-B1)	Scavenger receptor (SR)	Chinese Hamster	Chinese hamster ovary (CHO) cell	NA	NA	NA	NA	NA	ELISA	7520436	1994	NA
PRRID_0031	maleylated BSA Click for more detail	NA	MKWVTFISLLLLFSSAYSRGVFRRDTHKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA	607	Protein	Natural	Immunostimulant	Scavenger receptor B-1 (SR-B1)	Scavenger receptor (SR)	Chinese Hamster	Chinese hamster ovary (CHO) cell	NA	NA	NA	NA	NA	ELISA	7520436	1994	NA
PRRID_0032	Acetylated LDL Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Immunostimulant	dSR-C1	Scavenger receptor (SR)	Drosophila melanogaster	NA	two complement control protein (CCP) domains and somatomedin B, MAM, and mucin-like domains	NA	NA	NA	NA	NA	7732030	1995	NA
PRRID_0032	Acetylated LDL Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Immunostimulant	dSR-C1	Scavenger receptor (SR)	Drosophila melanogaster	NA	two complement control protein (CCP) domains and somatomedin B, MAM, and mucin-like domains	NA	NA	NA	NA	NA	7732030	1995	NA
PRRID_0033	Acetylated LDL Click for more detail	NA	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Acetylated LDL is a potent ligand for MARCO	Macrophage receptor with collagenous structure (MARCO)	Scavenger receptor (SR)	Mice	Macrophages	NA	A2RT24.fasta	A2RT24	518	It plays a role in immunological reactions.	Immunoprecipitation	7867067	1995	Pubchem Assay
PRRID_0033	Acetylated LDL Click for more detail	NA	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Acetylated LDL is a potent ligand for MARCO	Macrophage receptor with collagenous structure (MARCO)	Scavenger receptor (SR)	Mice	Macrophages	NA	A2RT24.fasta	A2RT24	518	It plays a role in immunological reactions.	Immunoprecipitation	7867067	1995	Pubchem Assay
PRRID_0034	Acetylated LDL Click for more detail	Host (Endogenous) (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Acetylated-LDL is a potent activator of MSR.	Macrophage Scavenger Receptor (MSR)	Scavenger receptor (SR)	Human	Macrophages	NA	P21757.fasta	P21757	451	The MSR mediates the endocytic uptake and degradation of LDL.	NA	7607209	1995	Pubchem Assay
PRRID_0034	Acetylated LDL Click for more detail	Host (Endogenous) (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Acetylated-LDL is a potent activator of MSR.	Macrophage Scavenger Receptor (MSR)	Scavenger receptor (SR)	Human	Macrophages	NA	P21757.fasta	P21757	451	The MSR mediates the endocytic uptake and degradation of LDL.	NA	7607209	1995	Pubchem Assay
PRRID_0036	Advanced Glycation End Products (AGE) Click for more detail	Host (Endogenous) (others)	NA	NA	Protein	Natural	AGE is a potent activator of MSR.	Macrophage Scavenger Receptor (MSR)	Scavenger receptor (SR)	Human	Macrophages	NA	P21757.fasta	P21757	451	The MSR mediates the endocytic uptake and degradation of AGE proteins.	NA	7607209	1995	Pubchem Assay
PRRID_0036	Advanced Glycation End Products (AGE) Click for more detail	Host (Endogenous) (others)	NA	NA	Protein	Natural	AGE is a potent activator of MSR.	Macrophage Scavenger Receptor (MSR)	Scavenger receptor (SR)	Human	Macrophages	NA	P21757.fasta	P21757	451	The MSR mediates the endocytic uptake and degradation of AGE proteins.	NA	7607209	1995	Pubchem Assay
PRRID_0037	Escherichia coli Click for more detail	E. coli(Bacteria)	NA	NA	Whole cell	Natural	E.coli binds with MARCO with high affinity.	Macrophage receptor with collagenous structure (MARCO)	Scavenger receptor (SR)	Mice	Macrophages	NA	A2RT24.fasta	A2RT24	518	It plays a role in immunological reactions.	Immunoprecipitation	7867067	1995	Pubchem Assay
PRRID_0037	Escherichia coli Click for more detail	E. coli(Bacteria)	NA	NA	Whole cell	Natural	E.coli binds with MARCO with high affinity.	Macrophage receptor with collagenous structure (MARCO)	Scavenger receptor (SR)	Mice	Macrophages	NA	A2RT24.fasta	A2RT24	518	It plays a role in immunological reactions.	Immunoprecipitation	7867067	1995	Pubchem Assay
PRRID_0038	Laminarin Click for more detail	laminaria (others)	C(C1C(C(C(C(O1)O)O)OC2C(C(C(C(O2)CO)O)OC3C(C(C(C(O3)CO)O)O)O)O)O)O	NA	Carbohydrate	Natural	Immunostimulant	Scavenger receptor C-1 (SR-C1)	Scavenger receptor (SR)	Drosophila melanogaster	NA	two complement control protein (CCP) domains and somatomedin B, MAM, and mucin-like domains	NA	NA	NA	NA	NA	7732030	1995	NA
PRRID_0038	Laminarin Click for more detail	laminaria (others)	C(C1C(C(C(C(O1)O)O)OC2C(C(C(C(O2)CO)O)OC3C(C(C(C(O3)CO)O)O)O)O)O)O	NA	Carbohydrate	Natural	Immunostimulant	Scavenger receptor C-1 (SR-C1)	Scavenger receptor (SR)	Drosophila melanogaster	NA	two complement control protein (CCP) domains and somatomedin B, MAM, and mucin-like domains	NA	NA	NA	NA	NA	7732030	1995	NA
PRRID_0042	poly D-glutamic acid Click for more detail	synthetic polypeptyide (others)	C(CC(=O)O)C(C(=O)O)N	NA	Peptide	Natural	Immunostimulant	Scavenger receptor C-1 (SR-C1)	Scavenger receptor (SR)	Drosophila melanogaster	NA	two complement control protein (CCP) domains and somatomedin B, MAM, and mucin-like domains	NA	NA	NA	NA	NA	7732030	1995	NA
PRRID_0042	poly D-glutamic acid Click for more detail	synthetic polypeptyide (others)	C(CC(=O)O)C(C(=O)O)N	NA	Peptide	Natural	Immunostimulant	Scavenger receptor C-1 (SR-C1)	Scavenger receptor (SR)	Drosophila melanogaster	NA	two complement control protein (CCP) domains and somatomedin B, MAM, and mucin-like domains	NA	NA	NA	NA	NA	7732030	1995	NA
PRRID_0043	Staphylococcus aureus Click for more detail	S. aureus (Bacteria)	NA	NA	Whole cell	Natural	S. aureus binds with MARCO with high affinity	Macrophage receptor with collagenous structure (MARCO)	Scavenger receptor (SR)	Mice	Macrophages	NA	A2RT24.fasta	A2RT24	518	It plays a role in immunological reactions.	Immunoprecipitation	7867067	1995	Pubchem Assay
PRRID_0043	Staphylococcus aureus Click for more detail	S. aureus (Bacteria)	NA	NA	Whole cell	Natural	S. aureus binds with MARCO with high affinity	Macrophage receptor with collagenous structure (MARCO)	Scavenger receptor (SR)	Mice	Macrophages	NA	A2RT24.fasta	A2RT24	518	It plays a role in immunological reactions.	Immunoprecipitation	7867067	1995	Pubchem Assay
PRRID_0046	amyloid beta peptide Click for more detail	Endogenous (others)	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN	770	Peptide	Natural	Immunostimulant	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	ELISA	8816718	1996	NA
PRRID_0046	amyloid beta peptide Click for more detail	Endogenous (others)	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN	770	Peptide	Natural	Immunostimulant	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	ELISA	8816718	1996	NA
PRRID_0047	amyloid beta peptide Click for more detail	Endogenous (others)	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN	770	Peptide	Natural	Immunostimulant	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	ELISA	8816718	1996	NA
PRRID_0047	amyloid beta peptide Click for more detail	Endogenous (others)	MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN	770	Peptide	Natural	Immunostimulant	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	ELISA	8816718	1996	NA
PRRID_0048	Apoptotic thymocytes Click for more detail	Host (Endogenous) (others)	NA	NA	Whole cell	Natural	Apoptotic thymocytes interacts with Scavenger receptor class A, which leads to the uptake and degradation.	Scavenger receptor class A	Scavenger receptor (SR)	Mice	Thymic macrophages	NA	Q68EF1.fasta	Q68EF1	474	SR-A may play a role in the clearance of dying cells in the thymus.	Phagocytosis Assay	8901603	1996	Pubchem Assay
PRRID_0048	Apoptotic thymocytes Click for more detail	Host (Endogenous) (others)	NA	NA	Whole cell	Natural	Apoptotic thymocytes interacts with Scavenger receptor class A, which leads to the uptake and degradation.	Scavenger receptor class A	Scavenger receptor (SR)	Mice	Thymic macrophages	NA	Q68EF1.fasta	Q68EF1	474	SR-A may play a role in the clearance of dying cells in the thymus.	Phagocytosis Assay	8901603	1996	Pubchem Assay
PRRID_0049	Fractionated [(3)H]heparin Click for more detail	Host (Endogenous) (others)	CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O	NA	Glycosaminoglycan	Natural	Fractionated [(3)H]heparin is a potent ligand for scavenger receptor A-I	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	Rat	Kupffer cells	NA	NA	NA	NA	Adsorptive endocytosis of polypeptides and phagocytosis.	NA	8860963	1996	NA
PRRID_0049	Fractionated [(3)H]heparin Click for more detail	Host (Endogenous) (others)	CC(=O)NC1C(C(C(OC1O)COS(=O)(=O)O)OC2C(C(C(C(O2)C(=O)O)OC3C(C(C(C(O3)CO)OC4C(C(C(C(O4)C(=O)O)O)O)OS(=O)(=O)O)OS(=O)(=O)O)NS(=O)(=O)O)O)OS(=O)(=O)O)O	NA	Glycosaminoglycan	Natural	Fractionated [(3)H]heparin is a potent ligand for scavenger receptor A-I	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	Rat	Kupffer cells	NA	NA	NA	NA	Adsorptive endocytosis of polypeptides and phagocytosis.	NA	8860963	1996	NA
PRRID_0052	maleylated BSA Click for more detail	NA	MKWVTFISLLLLFSSAYSRGVFRRDTHKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA	607	Protein	Natural	immunostimulantt	Scavenger receptor B-1 (SR-B1)	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	NA	8560269	1996	NA
PRRID_0052	maleylated BSA Click for more detail	NA	MKWVTFISLLLLFSSAYSRGVFRRDTHKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAKTCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNECFLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAPELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLASSARQRLRCASIQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLECADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENLPPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKEYEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYGFQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDYLSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAFDEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFVAFVDKCCAADDKEACFAVEGPKLVVSTQTALA	607	Protein	Natural	immunostimulantt	Scavenger receptor B-1 (SR-B1)	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	NA	8560269	1996	NA
PRRID_0055	Acetylated LDL Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Immunostimulant	Scavenger receptor expressed by endothelial cells 1	Scavenger receptor (SR)	Chinese Hamster	Chinese hamster ovary cells	Lectin-like domains	NA	NA	NA	NA	ELISA	9395444	1997	NA
PRRID_0055	Acetylated LDL Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Immunostimulant	Scavenger receptor expressed by endothelial cells 1	Scavenger receptor (SR)	Chinese Hamster	Chinese hamster ovary cells	Lectin-like domains	NA	NA	NA	NA	ELISA	9395444	1997	NA
PRRID_0057	Acetylated LDL Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	elicit innate immune response	Scavenger receptor A II	Scavenger receptor (SR)	Mice	Macrophages	NA	Q08857.fasta	Q08857	472	production of pro-inflammatory cytokines	NA	9069289	1997	Pubchem Assay
PRRID_0057	Acetylated LDL Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	elicit innate immune response	Scavenger receptor A II	Scavenger receptor (SR)	Mice	Macrophages	NA	Q08857.fasta	Q08857	472	production of pro-inflammatory cytokines	NA	9069289	1997	Pubchem Assay
PRRID_0059	Advanced Glycation End Products (AGE) Click for more detail	Endogenous (others)	NA	NA	Others	Natural	elicit innate immune response	Scavenger receptor A II	Scavenger receptor (SR)	Mice	Macrophages	NA	Q08857.fasta	Q08857	472	production of pro-inflammatory cytokines	NA	9069289	1997	Pubchem Assay
PRRID_0059	Advanced Glycation End Products (AGE) Click for more detail	Endogenous (others)	NA	NA	Others	Natural	elicit innate immune response	Scavenger receptor A II	Scavenger receptor (SR)	Mice	Macrophages	NA	Q08857.fasta	Q08857	472	production of pro-inflammatory cytokines	NA	9069289	1997	Pubchem Assay
PRRID_0060	Advanced Glycation End-products (AGE)-BSA Click for more detail	Human (others)	NA	NA	Protein	Natural	AGE-modified proteins binds to scavenger receptor with high affinity.	Scavenger receptor class A	Scavenger receptor (SR)	Human	hepatic sinusoidal Kupffer and endothelial cells	NA	NA	NA	NA	AGE-proteins are eliminated very efficiently from the circulation by scavenger-receptor-mediated endocytosis in both LECs and KCs.	NA	9065778	1997	NA
PRRID_0060	Advanced Glycation End-products (AGE)-BSA Click for more detail	Human (others)	NA	NA	Protein	Natural	AGE-modified proteins binds to scavenger receptor with high affinity.	Scavenger receptor class A	Scavenger receptor (SR)	Human	hepatic sinusoidal Kupffer and endothelial cells	NA	NA	NA	NA	AGE-proteins are eliminated very efficiently from the circulation by scavenger-receptor-mediated endocytosis in both LECs and KCs.	NA	9065778	1997	NA
PRRID_0061	Advanced Glycation End-products (AGE)-Hb Click for more detail	Human (others)	NA	NA	Protein	Natural	AGE-modified proteins binds to scavenger receptor with high affinity.	Scavenger receptor class A	Scavenger receptor (SR)	Human	hepatic sinusoidal Kupffer and endothelial cells	NA	NA	NA	NA	AGE-proteins are eliminated very efficiently from the circulation by scavenger-receptor-mediated endocytosis in both LECs and KCs.	NA	9065778	1997	NA
PRRID_0061	Advanced Glycation End-products (AGE)-Hb Click for more detail	Human (others)	NA	NA	Protein	Natural	AGE-modified proteins binds to scavenger receptor with high affinity.	Scavenger receptor class A	Scavenger receptor (SR)	Human	hepatic sinusoidal Kupffer and endothelial cells	NA	NA	NA	NA	AGE-proteins are eliminated very efficiently from the circulation by scavenger-receptor-mediated endocytosis in both LECs and KCs.	NA	9065778	1997	NA
PRRID_0062	oxidized LDL (OxLDL) Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Immunostimulant	Scavenger receptor expressed by endothelial cells 1	Scavenger receptor (SR)	Chinese Hamster	Chinese hamster ovary cells	Lectin-like domains	NA	NA	NA	NA	ELISA	9395444	1997	NA
PRRID_0062	oxidized LDL (OxLDL) Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Immunostimulant	Scavenger receptor expressed by endothelial cells 1	Scavenger receptor (SR)	Chinese Hamster	Chinese hamster ovary cells	Lectin-like domains	NA	NA	NA	NA	ELISA	9395444	1997	NA
PRRID_0064	oxidized LDL (OxLDL) Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	elicit innate immune response	Scavenger receptor A II	Scavenger receptor (SR)	Mice	Macrophages	NA	Q08857.fasta	Q08857	472	production of pro-inflammatory cytokines	NA	9069289	1997	Pubchem Assay
PRRID_0064	oxidized LDL (OxLDL) Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	elicit innate immune response	Scavenger receptor A II	Scavenger receptor (SR)	Mice	Macrophages	NA	Q08857.fasta	Q08857	472	production of pro-inflammatory cytokines	NA	9069289	1997	Pubchem Assay
PRRID_0065	Acetylated LDL Click for more detail	Host (Endogenous) (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	AcLDL pretreatment increased expression of macrosialin	Microsialin	Scavenger receptor (SR)	Mice	Peritoneal macrophages	NA	A0A0R4J1C8.fasta	A0A0R4J1C8	335	It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages.	Endocytic degradation assays	9598839	1998	Pubchem Assay
PRRID_0065	Acetylated LDL Click for more detail	Host (Endogenous) (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	AcLDL pretreatment increased expression of macrosialin	Microsialin	Scavenger receptor (SR)	Mice	Peritoneal macrophages	NA	A0A0R4J1C8.fasta	A0A0R4J1C8	335	It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages.	Endocytic degradation assays	9598839	1998	Pubchem Assay
PRRID_0067	Gram-negative Click for more detail	Gram-positive and negative bacteria	NA	NA	NA	Natural	NA	Macrophage receptor with collagenous structure (MARCO)	Scavenger receptor (SR)	Human	Macrophages	cysteine-rich motif (SRCR)	Q9UEW3.fasta	Q9UEW3	520	MARCO is likely to play a role in host defense.	NA	9468508	1998	Pubchem Assay
PRRID_0067	Gram-negative Click for more detail	Gram-positive and negative bacteria	NA	NA	NA	Natural	NA	Macrophage receptor with collagenous structure (MARCO)	Scavenger receptor (SR)	Human	Macrophages	cysteine-rich motif (SRCR)	Q9UEW3.fasta	Q9UEW3	520	MARCO is likely to play a role in host defense.	NA	9468508	1998	Pubchem Assay
PRRID_0070	Minimally oxidized LDL (MM-LDL) Click for more detail	Host (Endogenous) (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	MM-LDL pretreatment induced a clear increase of cell association and increase both mRNAlevels and protein levels of scavenger receptor A, CD36, and macrosialin.	Microsialin	Scavenger receptor (SR)	Mice	Peritoneal macrophages	NA	A0A0R4J1C8.fasta	A0A0R4J1C8	335	It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages.	Endocytic degradation assays	9598839	1998	Pubchem Assay
PRRID_0070	Minimally oxidized LDL (MM-LDL) Click for more detail	Host (Endogenous) (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	MM-LDL pretreatment induced a clear increase of cell association and increase both mRNAlevels and protein levels of scavenger receptor A, CD36, and macrosialin.	Microsialin	Scavenger receptor (SR)	Mice	Peritoneal macrophages	NA	A0A0R4J1C8.fasta	A0A0R4J1C8	335	It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages.	Endocytic degradation assays	9598839	1998	Pubchem Assay
PRRID_0071	oxidized LDL (OxLDL) Click for more detail	Host (Endogenous) (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	OxLDL pretreatment increased expression of macrosialin.	Microsialin	Scavenger receptor (SR)	Mice	Peritoneal macrophages	NA	A0A0R4J1C8.fasta	A0A0R4J1C8	335	It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages.	Endocytic degradation assays	9598839	1998	Pubchem Assay
PRRID_0071	oxidized LDL (OxLDL) Click for more detail	Host (Endogenous) (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	OxLDL pretreatment increased expression of macrosialin.	Microsialin	Scavenger receptor (SR)	Mice	Peritoneal macrophages	NA	A0A0R4J1C8.fasta	A0A0R4J1C8	335	It leads to the binding and uptake of oxidised form of LDL by resident mouse peritoneal macrophages.	Endocytic degradation assays	9598839	1998	Pubchem Assay
PRRID_0073	Gram-positive bacteria Click for more detail	Gram-positive and negative bacteria	NA	NA	NA	Natural	NA	Macrophage receptor with collagenous structure (MARCO)	Scavenger receptor (SR)	Human	Macrophages	cysteine-rich motif (SRCR)	Q9UEW3.fasta	Q9UEW3	520	MARCO is likely to play a role in host defense.	NA	9468508	1998	Pubchem Assay
PRRID_0073	Gram-positive bacteria Click for more detail	Gram-positive and negative bacteria	NA	NA	NA	Natural	NA	Macrophage receptor with collagenous structure (MARCO)	Scavenger receptor (SR)	Human	Macrophages	cysteine-rich motif (SRCR)	Q9UEW3.fasta	Q9UEW3	520	MARCO is likely to play a role in host defense.	NA	9468508	1998	Pubchem Assay
PRRID_0091	oxidized LDL (OxLDL) Click for more detail	Host (Endogenous) (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Ox-LDL binds with SR-PSOX with high affinity.	Scavenger receptor PSOX (SR-PSOX)	Scavenger receptor (SR)	PMA treated THP-1 cells	Macrophages	NA	NA	NA	NA	SR-PSOX specifically binds with high affinity, internalize and degrade OxLDL, hence play important roles in pathophysiology including atherogenesis.	ELISA	11060282	2000	NA
PRRID_0091	oxidized LDL (OxLDL) Click for more detail	Host (Endogenous) (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Ox-LDL binds with SR-PSOX with high affinity.	Scavenger receptor PSOX (SR-PSOX)	Scavenger receptor (SR)	PMA treated THP-1 cells	Macrophages	NA	NA	NA	NA	SR-PSOX specifically binds with high affinity, internalize and degrade OxLDL, hence play important roles in pathophysiology including atherogenesis.	ELISA	11060282	2000	NA
PRRID_0092	oxidized LDL (OxLDL) Click for more detail	Host (Endogenous) (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Ox-LDL binds with SR-PSOX with high affinity.	Scavenger receptor PSOX (SR-PSOX)	Scavenger receptor (SR)	Human	Macrophages	NA	Q9H2A7.fasta	Q9H2A7	254	SR-PSOX specifically binds with high affinity, internalize and degrade OxLDL, hence play important roles in pathophysiology including atherogenesis.	ELISA	11060282	2000	Pubchem Assay
PRRID_0092	oxidized LDL (OxLDL) Click for more detail	Host (Endogenous) (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Natural	Ox-LDL binds with SR-PSOX with high affinity.	Scavenger receptor PSOX (SR-PSOX)	Scavenger receptor (SR)	Human	Macrophages	NA	Q9H2A7.fasta	Q9H2A7	254	SR-PSOX specifically binds with high affinity, internalize and degrade OxLDL, hence play important roles in pathophysiology including atherogenesis.	ELISA	11060282	2000	Pubchem Assay
PRRID_0094	Silica Click for more detail	Environment particle (others)	O=[Si]=O	NA	Chemical Compunds	Natural	Silica particulates bind to the scavenger receptor and initiate apoptosis	Scavenger receptor A II	Scavenger receptor (SR)	Chinese Hamster	Macrophages	NA	NA	NA	NA	SR-A II is directly involved with silica toxicity and that certain scavenger receptor ligands may have an important role in regulating macrophage apoptosis.	ELISA	10637133	2000	NA
PRRID_0094	Silica Click for more detail	Environment particle (others)	O=[Si]=O	NA	Chemical Compunds	Natural	Silica particulates bind to the scavenger receptor and initiate apoptosis	Scavenger receptor A II	Scavenger receptor (SR)	Chinese Hamster	Macrophages	NA	NA	NA	NA	SR-A II is directly involved with silica toxicity and that certain scavenger receptor ligands may have an important role in regulating macrophage apoptosis.	ELISA	10637133	2000	NA
PRRID_0104	Lipopolysaccharide (LPS) Click for more detail	Gram-negative bacteria	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	Immunostimulant	Scavenger receptor class A	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	NA	1852209	2001	NA
PRRID_0104	Lipopolysaccharide (LPS) Click for more detail	Gram-negative bacteria	CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCC	NA	Lipopolysaccharide (LPS)	Natural	Immunostimulant	Scavenger receptor class A	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	NA	1852209	2001	NA
PRRID_0106	NA Click for more detail	Gram-negative bacteria	NA	NA	Others	Natural	Immunostimulant	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	NA	1852209	2001	NA
PRRID_0106	NA Click for more detail	Gram-negative bacteria	NA	NA	Others	Natural	Immunostimulant	Scavenger receptor A I (SR-A I)	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	NA	1852209	2001	NA
PRRID_0107	NA Click for more detail	Gram-negative bacteria	NA	NA	Others	Natural	Immunostimulant	Scavenger receptor A II	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	NA	1852209	2001	NA
PRRID_0107	NA Click for more detail	Gram-negative bacteria	NA	NA	Others	Natural	Immunostimulant	Scavenger receptor A II	Scavenger receptor (SR)	NA	NA	NA	NA	NA	NA	NA	NA	1852209	2001	NA
PRRID_0109	oxidized LDL (OxLDL) Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Synthetic	Ox-LDL binds with SR-PSOX with high affinity.	Scavenger Receptor for PhosphatidylSerine and Oxidized lipoprotein (SR-PSOX)	Scavenger receptor (SR)	Human	Macrophages	NA	Q9H2A7.fasta	Q9H2A7	254	SR-PSOX is involved in Ox-LDL uptake and subsequent foam cell transformation in macrophages in vivo and thus may play important roles in human atherosclerotic lesion formation.	ELISA	11701468	2001	Pubchem Assay
PRRID_0109	oxidized LDL (OxLDL) Click for more detail	Endogenous (others)	CC1CCC2(C(C3C(O2)CC4C3(CCC5C4CCC6C5(CCC(C6)O)C)C)C)NC1	NA	Lipoprotein	Synthetic	Ox-LDL binds with SR-PSOX with high affinity.	Scavenger Receptor for PhosphatidylSerine and Oxidized lipoprotein (SR-PSOX)	Scavenger receptor (SR)	Human	Macrophages	NA	Q9H2A7.fasta	Q9H2A7	254	SR-PSOX is involved in Ox-LDL uptake and subsequent foam cell transformation in macrophages in vivo and thus may play important roles in human atherosclerotic lesion formation.	ELISA	11701468	2001	Pubchem Assay
PRRID_0133	Hypochlorite modified HDL Click for more detail	Host (Endogenous) (others)	CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C	NA	Lipoprotein	Natural	It has a high affinity for the Lectin-like oxidized low density lipoprotein receptor 1 (LOX-1).	Scavenger receptor class B, type I (SR-BI)	Scavenger receptor (SR)	Mice (Murine)	CHO Cells‚ÄîldlA cells	NA	Q06BI8.fasta	Q06BI8	494	It impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport.	NA	12070141	2002	Pubchem Assay
PRRID_0133	Hypochlorite modified HDL Click for more detail	Host (Endogenous) (others)	CC(C)CCCC(C)C1CCC2C1(CCC3C2CC=C4C3(CCC(C4)O)C)C	NA	Lipoprotein	Natural	It has a high affinity for the Lectin-like oxidized low density lipoprotein receptor 1 (LOX-1).	Scavenger receptor class B, type I (SR-BI)	Scavenger receptor (SR)	Mice (Murine)	CHO Cells‚ÄîldlA cells	NA	Q06BI8.fasta	Q06BI8	494	It impairs high density lipoprotein-dependent selective lipid uptake and reverse cholesterol transport.	NA	12070141	2002	Pubchem Assay
PRRID_0144	Others Click for more detail	Gram-positive and negative bacteria	NA	NA	NA	Natural	Immunostimulant	Fasciclin EGF-like laminin-typeEGF-like and link domain-containing scavenger receptor 1/2	Scavenger receptor (SR)	Chinese Hamster	Spleen and lymph node	fasciclin, EGF-like, laminin-type EGF-like, and link domain	NA	NA	NA	NA	ELISA	12077138	2002	NA
PRRID_0144	Others Click for more detail	Gram-positive and negative bacteria	NA	NA	NA	Natural	Immunostimulant	Fasciclin EGF-like laminin-typeEGF-like and link domain-containing scavenger receptor 1/2	Scavenger receptor (SR)	Chinese Hamster	Spleen and lymph node	fasciclin, EGF-like, laminin-type EGF-like, and link domain	NA	NA	NA	NA	ELISA	12077138	2002	NA
PRRID_0165	Escherichia coli Click for more detail	E. coli(Bacteria)	NA	NA	Whole cell	Natural	The recognition specificity for bacteria is determine by the chemokine domain of SR-PSOX/CXCL16.	Scavenger receptor PSOX/CXCL16 (SR-PSOX/CXCL16)	Scavenger receptor (SR)	Human	Macrophages and Dendritic cells	Chemokine domain	Q9H2A7.fasta	Q9H2A7	254	SR-PSOX/CXCL16 mediates bacterial adhesion and phagocytosis.	ELISA	12902461	2003	Pubchem Assay
PRRID_0165	Escherichia coli Click for more detail	E. coli(Bacteria)	NA	NA	Whole cell	Natural	The recognition specificity for bacteria is determine by the chemokine domain of SR-PSOX/CXCL16.	Scavenger receptor PSOX/CXCL16 (SR-PSOX/CXCL16)	Scavenger receptor (SR)	Human	Macrophages and Dendritic cells	Chemokine domain	Q9H2A7.fasta	Q9H2A7	254	SR-PSOX/CXCL16 mediates bacterial adhesion and phagocytosis.	ELISA	12902461	2003	Pubchem Assay
PRRID_0168	gp96 (GRP94) Click for more detail	Host (Endogenous) (others)	MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL	803	Protein	Natural	elicits antigen-presenting cell (APC) activation and can direct peptides into the cross- presentation pathways of APC	Scavenger receptor class A	Scavenger receptor (SR)	C57/BL6 mice	macrophages and dendritic cells	NA	Q08857.fasta	Q08857	472	serves a primary role in gp96 and calreticulin recognition and internalization	NA	14609958	2003	Pubchem Assay
PRRID_0168	gp96 (GRP94) Click for more detail	Host (Endogenous) (others)	MRALWVLGLCCVLLTFGSVRADDEVDVDGTVEEDLGKSREGSRTDDEVVQREEEAIQLDGLNASQIRELREKSEKFAFQAEVNRMMKLIINSLYKNKEIFLRELISNASDALDKIRLISLTDENALSGNEELTVKIKCDKEKNLLHVTDTGVGMTREELVKNLGTIAKSGTSEFLNKMTEAQEDGQSTSELIGQFGVGFYSAFLVADKVIVTSKHNNDTQHIWESDSNEFSVIADPRGNTLGRGTTITLVLKEEASDYLELDTIKNLVKKYSQFINFPIYVWSSKTETVEEPMEEEEAAKEEKEESDDEAAVEEEEEEKKPKTKKVEKTVWDWELMNDIKPIWQRPSKEVEEDEYKAFYKSFSKESDDPMAYIHFTAEGEVTFKSILFVPTSAPRGLFDEYGSKKSDYIKLYVRRVFITDDFHDMMPKYLNFVKGVVDSDDLPLNVSRETLQQHKLLKVIRKKLVRKTLDMIKKIADDKYNDTFWKEFGTNIKLGVIEDHSNRTRLAKLLRFQSSHHPTDITSLDQYVERMKEKQDKIYFMAGSSRKEAESSPFVERLLKKGYEVIYLTEPVDEYCIQALPEFDGKRFQNVAKEGVKFDESEKTKESREAVEKEFEPLLNWMKDKALKDKIEKAVVSQRLTESPCALVASQYGWSGNMERIMKAQAYQTGKDISTNYYASQKKTFEINPRHPLIRDMLRRIKEDEDDKTVLDLAVVLFETATLRSGYLLPDTKAYGDRIERMLRLSLNIDPDAKVEEEPEEEPEETAEDTTEDTEQDEDEEMDVGTDEEEETAKESTAEKDEL	803	Protein	Natural	elicits antigen-presenting cell (APC) activation and can direct peptides into the cross- presentation pathways of APC	Scavenger receptor class A	Scavenger receptor (SR)	C57/BL6 mice	macrophages and dendritic cells	NA	Q08857.fasta	Q08857	472	serves a primary role in gp96 and calreticulin recognition and internalization	NA	14609958	2003	Pubchem Assay
PRRID_0187	Staphylococcus aureus Click for more detail	S. aureus (Bacteria)	NA	NA	Whole cell	Natural	The recognition specificity for bacteria is determine by the chemokine domain of SR-PSOX/CXCL16.	Scavenger receptor PSOX/CXCL16 (SR-PSOX/CXCL16)	Scavenger receptor (SR)	Human	Macrophages and Dendritic cells	Chemokine domain	Q9H2A7.fasta	Q9H2A7	254	SR-PSOX/CXCL16 mediates bacterial adhesion and phagocytosis.	ELISA	12902461	2003	Pubchem Assay
PRRID_0187	Staphylococcus aureus Click for more detail	S. aureus (Bacteria)	NA	NA	Whole cell	Natural	The recognition specificity for bacteria is determine by the chemokine domain of SR-PSOX/CXCL16.	Scavenger receptor PSOX/CXCL16 (SR-PSOX/CXCL16)	Scavenger receptor (SR)	Human	Macrophages and Dendritic cells	Chemokine domain	Q9H2A7.fasta	Q9H2A7	254	SR-PSOX/CXCL16 mediates bacterial adhesion and phagocytosis.	ELISA	12902461	2003	Pubchem Assay
PRRID_0192	Advillin Click for more detail	Host (Endogenous) (others)	MSLSSAFRAVSNDPRIITWRIEKMELALVPLSAHGNFYEGDCYIVLSTRRVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIQATEVEMSWDSFNRGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPGLMTVLQDTLGRRSMIKPAVSDEIMDQQQKSSIMLYHVSDTAGQLSVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTTGLGKIFSTGKIAKIFQDKFDVSLLHTKPEVAAQERMVDDGKGQVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVNGKPHYILYIWQGRHASRDELAASAYRAVEVDQQFDGAPVQVRVSMGKEPRHFMAIFKGKLVIYEGGTSRKGNEEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKELVDLLCDGNADTVAEGQEPPEFWDLLGGKTAYANDKRLQQETLDVQVRLFECSNKTGRFLVTEVTDFTQEDLSPGDVMLLDTWDQVFLWIGAEANATEKKGALSTAQEYLVTHPSGRDPDTPILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKNELGDATAIVRITADMKNATLYLNPSDGEPKYYPVEVLLKGQNQELPEDVDPAKKENYLSEQDFVSVFGITRGQFTALPGWKQLQLKKERGLF	819	Protein	Natural	It induces neurite-like outgrowth.	Scavenger receptor expressed by endothelial cells 1 (SREC-I)	Scavenger receptor (SR)	Mice (Murine)	Fibroblastic L cells	Cytoplasmic domain	Q5ND28.fasta	Q5ND28	820	SREC-I lead to changes in cell morphology.	NA	15247299	2004	Pubchem Assay
PRRID_0192	Advillin Click for more detail	Host (Endogenous) (others)	MSLSSAFRAVSNDPRIITWRIEKMELALVPLSAHGNFYEGDCYIVLSTRRVGSLLSQNIHFWIGKDSSQDEQSCAAIYTTQLDDYLGGSPVQHREVQYHESDTFRGYFKQGIIYKKGGVASGMKHVETNTYDVKRLLHVKGKRNIQATEVEMSWDSFNRGDVFLLDLGMVIIQWNGPESNSGERLKAMLLAKDIRDRERGGRAEIGVIEGDKEAASPGLMTVLQDTLGRRSMIKPAVSDEIMDQQQKSSIMLYHVSDTAGQLSVTEVATRPLVQDLLNHDDCYILDQSGTKIYVWKGKGATKVEKQAAMSKALDFIKMKGYPSSTNVETVNDGAESAMFKQLFQKWSVKDQTTGLGKIFSTGKIAKIFQDKFDVSLLHTKPEVAAQERMVDDGKGQVEVWRIENLELVPVEYQWHGFFYGGDCYLVLYTYDVNGKPHYILYIWQGRHASRDELAASAYRAVEVDQQFDGAPVQVRVSMGKEPRHFMAIFKGKLVIYEGGTSRKGNEEPDPPVRLFQIHGNDKSNTKAVEVSASASSLNSNDVFLLRTQAEHYLWYGKGSSGDERAMAKELVDLLCDGNADTVAEGQEPPEFWDLLGGKTAYANDKRLQQETLDVQVRLFECSNKTGRFLVTEVTDFTQEDLSPGDVMLLDTWDQVFLWIGAEANATEKKGALSTAQEYLVTHPSGRDPDTPILIIKQGFEPPTFTGWFLAWDPHIWSEGKSYEQLKNELGDATAIVRITADMKNATLYLNPSDGEPKYYPVEVLLKGQNQELPEDVDPAKKENYLSEQDFVSVFGITRGQFTALPGWKQLQLKKERGLF	819	Protein	Natural	It induces neurite-like outgrowth.	Scavenger receptor expressed by endothelial cells 1 (SREC-I)	Scavenger receptor (SR)	Mice (Murine)	Fibroblastic L cells	Cytoplasmic domain	Q5ND28.fasta	Q5ND28	820	SREC-I lead to changes in cell morphology.	NA	15247299	2004	Pubchem Assay
PRRID_0193	calreticulin Click for more detail	Host (Endogenous) (others)	MLLSVPLLLGLLGLAAAEPAVYFKEQFLDGDDWTNRWVESKHKSDFGKFVLSSGKFYGDQEKDKGLQTSQDARFYALSARFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPGSLDQKDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDAAKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDANIYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKASEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDEDDRDEDEEDEDEKEEDEEDTTPGQTKDEL	417	Protein	Natural	NA	SREC-I	Scavenger receptor (SR)	Chinese Hamster	ovary cells	NA	NA	NA	NA	mediates the endocytosis of calreticulin and gp96	NA	15371419	2004	NA
PRRID_0193	calreticulin Click for more detail	Host (Endogenous) (others)	MLLSVPLLLGLLGLAAAEPAVYFKEQFLDGDDWTNRWVESKHKSDFGKFVLSSGKFYGDQEKDKGLQTSQDARFYALSARFEPFSNKGQTLVVQFTVKHEQNIDCGGGYVKLFPGSLDQKDMHGDSEYNIMFGPDICGPGTKKVHVIFNYKGKNVLINKDIRCKDDEFTHLYTLIVRPDNTYEVKIDNSQVESGSLEDDWDFLPPKKIKDPDAAKPEDWDERAKIDDPTDSKPEDWDKPEHIPDPDAKKPEDWDEEMDGEWEPPVIQNPEYKGEWKPRQIDNPDYKGTWIHPEIDNPEYSPDANIYAYDSFAVLGLDLWQVKSGTIFDNFLITNDEAYAEEFGNETWGVTKASEKQMKDKQDEEQRLKEEEEDKKRKEEEEAEDKEDEDDRDEDEEDEDEKEEDEEDTTPGQTKDEL	417	Protein	Natural	NA	SREC-I	Scavenger receptor (SR)	Chinese Hamster	ovary cells	NA	NA	NA	NA	mediates the endocytosis of calreticulin and gp96	NA	15371419	2004	NA

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