Browse result page of PRRDB 2.0

PRRIDName of LigandSource of ligandSequence of LigandLength of Ligand Type of Ligand OccurenceRole of LigandName of ReceptorType of ReeptorSource of the ReceptorLocalizationDomainSequence of ReceptorSwiss prot IDLength of receptorFunction of ReceptorAssay usedPMIDYear of publicationPubchem assay
PRRID_0475dsRNA

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VirusNANANucleic AcidNaturalNAPGRP-S3Peptidoglycan Recognition Receptor (PGRPs)Chlamys farrerimantle, gill, kidney and gonadNAQ9VYX7.fastaQ9VYX7203It has the role in the inflammation.NA207131002010Pubchem Assay
PRRID_0475dsRNA

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VirusNANANucleic AcidNaturalNAPGRP-S3Peptidoglycan Recognition Receptor (PGRPs)Chlamys farrerimantle, gill, kidney and gonadNAQ9VYX7.fastaQ9VYX7203It has the role in the inflammation.NA207131002010Pubchem Assay
PRRID_0669Lys-type PGN

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Gram-positive bacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalNAPGRP-S1Peptidoglycan Recognition Receptor (PGRPs)Chlamys farrerimantle, gill, kidney and gonadNAQ9VYX7.fastaQ9VYX7203It leads to the degradation of PGN, induction of phagocytosis and activation of prophenoloxidase (proPO) systemNA207131002010Pubchem Assay
PRRID_0669Lys-type PGN

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Gram-positive bacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalNAPGRP-S1Peptidoglycan Recognition Receptor (PGRPs)Chlamys farrerimantle, gill, kidney and gonadNAQ9VYX7.fastaQ9VYX7203It leads to the degradation of PGN, induction of phagocytosis and activation of prophenoloxidase (proPO) systemNA207131002010Pubchem Assay
PRRID_0678meso-diaminopimelic Dap-type PGN

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Gram-positive bacteriaNANAPeptidoglycanNaturalNAPGRP-S1Peptidoglycan Recognition Receptor (PGRPs)Chlamys farrerimantle, gill, kidney and gonadNAQ9VYX7.fastaQ9VYX7203It leads to the degradation of PGN, induction of phagocytosis and activation of prophenoloxidase (proPO) systemNA207131002010Pubchem Assay
PRRID_0678meso-diaminopimelic Dap-type PGN

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Gram-positive bacteriaNANAPeptidoglycanNaturalNAPGRP-S1Peptidoglycan Recognition Receptor (PGRPs)Chlamys farrerimantle, gill, kidney and gonadNAQ9VYX7.fastaQ9VYX7203It leads to the degradation of PGN, induction of phagocytosis and activation of prophenoloxidase (proPO) systemNA207131002010Pubchem Assay
PRRID_0743Peptidoglycan (PGN)

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Vibrio anguillarum and Micrococcus lysodeikticus (Bacteria)CC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalNAPGRP-S1Peptidoglycan Recognition Receptor (PGRPs)Chlamys farrerimantle, gill, kidney and gonadNAQ9VYX7.fastaQ9VYX7203It leads to the degradation of PGN, induction of phagocytosis and activation of prophenoloxidase (proPO) systemELISA207131002010Pubchem Assay
PRRID_0743Peptidoglycan (PGN)

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Vibrio anguillarum and Micrococcus lysodeikticus (Bacteria)CC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalNAPGRP-S1Peptidoglycan Recognition Receptor (PGRPs)Chlamys farrerimantle, gill, kidney and gonadNAQ9VYX7.fastaQ9VYX7203It leads to the degradation of PGN, induction of phagocytosis and activation of prophenoloxidase (proPO) systemELISA207131002010Pubchem Assay
PRRID_0744Lipopolysaccharide (LPS)

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Vibrio anguillarum and Micrococcus lysodeikticus (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAPGRP-S1Peptidoglycan Recognition Receptor (PGRPs)Chlamys farrerimantle, gill, kidney and gonadNAQ9VYX7.fastaQ9VYX7203It leads to the degradation of PGN, induction of phagocytosis and activation of prophenoloxidase (proPO) systemELISA207131002010Pubchem Assay
PRRID_0744Lipopolysaccharide (LPS)

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Vibrio anguillarum and Micrococcus lysodeikticus (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalNAPGRP-S1Peptidoglycan Recognition Receptor (PGRPs)Chlamys farrerimantle, gill, kidney and gonadNAQ9VYX7.fastaQ9VYX7203It leads to the degradation of PGN, induction of phagocytosis and activation of prophenoloxidase (proPO) systemELISA207131002010Pubchem Assay
PRRID_0852β -1,3-glucan

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FungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAGlucanNaturalNAPGRP-S2Peptidoglycan Recognition Receptor (PGRPs)Chlamys farrerimantle, gill, kidney and gonadNAQ9VYX7.fastaQ9VYX7203It has the role in the inflammation.NA207131002010Pubchem Assay
PRRID_0852β -1,3-glucan

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FungiC(C1C(C(C(C(O1)OC2C(OC(C(C2O)O)OC3C(OC(C(C3O)O)O)CO)CO)O)O)O)ONAGlucanNaturalNAPGRP-S2Peptidoglycan Recognition Receptor (PGRPs)Chlamys farrerimantle, gill, kidney and gonadNAQ9VYX7.fastaQ9VYX7203It has the role in the inflammation.NA207131002010Pubchem Assay
PRRID_1486Mgn1703

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NANANAnovel, synthetic, dumb- bell-shaped, covalently closed Dna moleculeSyntheticimmuno modulatorsPGLYRP-2Peptidoglycan Recognition Receptor (PGRPs) Human patients with metastatic colorectal carcinoma (CRC)plasmacytoid dendritic cells (pDC) and B cellscell compartmentQ9NR96.fastaQ9NR961032TLR9 plays a crucial role in breaking tolerance and developing autoimmunityNA248167252014Pubchem_assay
PRRID_1486Mgn1703

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NANANAnovel, synthetic, dumb- bell-shaped, covalently closed Dna moleculeSyntheticimmuno modulatorsPGLYRP-2Peptidoglycan Recognition Receptor (PGRPs) Human patients with metastatic colorectal carcinoma (CRC)plasmacytoid dendritic cells (pDC) and B cellscell compartmentQ9NR96.fastaQ9NR961032TLR9 plays a crucial role in breaking tolerance and developing autoimmunityNA248167252014Pubchem_assay
PRRID_1487monomeric flagellin

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BacteriaMAQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQAARNANDGISVAQTTEGALSEINNNLQRVRELTVQATTGTNSESDLSSIQDEIKSRLDEIDRVSGQTQFNGVNVLAKNGSMKIQVGANDNQTITIDLKQIDAKTLGLDGFSVKNNDTVTTSAPVTAFGATTTNNIKLTGITLSTEAATDTGGTNPASIEGVYTDNGNDYYAKITGGDNDGKYYAVTVANDGTVTMATGATANATVTDANTTKATTITSGGTPVQIDNTAGSATANLGAVSLVKLQDSKGNDTDTYALKDTNGNLYAADVNETTGAVSVKTITYTDSSGAASSPTAVKLGGDDGKTEVVDIDGKTYDSADLNGGNLQTGLTAGGEALTAVANGKTTDPLKALDDAIASVDKFRSSLGAVQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAKANQVPQQVLSLLQG498Pattern-associated molecular patterns (PAMPs)NaturalIt directly interac with TLR 5 and induces immune responsePGLYRP-2Peptidoglycan Recognition Receptor (PGRPs)Micemonocyte/macrophages, DCsCell Surface (Exogenous)Q9JLF7.fastaQ9JLF7859It stimulates the production of proinflammatory cytokines, such as TNF-α, through signaling via the adaptor protein MyD88.reverse transcription–polymerase chain reaction (RT–PCR), real-time RT–PCR, flow cytometry, immunocytochemistry and Western blot analysis.248280222014Pubchem_assay
PRRID_1487monomeric flagellin

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BacteriaMAQVINTNSLSLITQNNINKNQSALSSSIERLSSGLRINSAKDDAAGQAIANRFTSNIKGLTQAARNANDGISVAQTTEGALSEINNNLQRVRELTVQATTGTNSESDLSSIQDEIKSRLDEIDRVSGQTQFNGVNVLAKNGSMKIQVGANDNQTITIDLKQIDAKTLGLDGFSVKNNDTVTTSAPVTAFGATTTNNIKLTGITLSTEAATDTGGTNPASIEGVYTDNGNDYYAKITGGDNDGKYYAVTVANDGTVTMATGATANATVTDANTTKATTITSGGTPVQIDNTAGSATANLGAVSLVKLQDSKGNDTDTYALKDTNGNLYAADVNETTGAVSVKTITYTDSSGAASSPTAVKLGGDDGKTEVVDIDGKTYDSADLNGGNLQTGLTAGGEALTAVANGKTTDPLKALDDAIASVDKFRSSLGAVQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLAKANQVPQQVLSLLQG498Pattern-associated molecular patterns (PAMPs)NaturalIt directly interac with TLR 5 and induces immune responsePGLYRP-2Peptidoglycan Recognition Receptor (PGRPs)Micemonocyte/macrophages, DCsCell Surface (Exogenous)Q9JLF7.fastaQ9JLF7859It stimulates the production of proinflammatory cytokines, such as TNF-α, through signaling via the adaptor protein MyD88.reverse transcription–polymerase chain reaction (RT–PCR), real-time RT–PCR, flow cytometry, immunocytochemistry and Western blot analysis.248280222014Pubchem_assay
PRRID_1495muramyl tripeptide

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Mycobacteria (Bacteria)CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)C(C)NC(=O)CCC(C(=O)N)NC(=O)C(C)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C)OC(=O)CCCCCCCCCCCCCCCNAPeptideNaturalin vitro activates NodPGLYRP-2Peptidoglycan Recognition Receptor (PGRPs)Miceintraepithelial T lymphocytesintracellular receptorsQ9JLF7.fastaQ9JLF7859recognises peptidoglycan of bacterial cell wallNA247793902014Pubchem_assay
PRRID_1495muramyl tripeptide

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Mycobacteria (Bacteria)CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)C(C)NC(=O)CCC(C(=O)N)NC(=O)C(C)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C)OC(=O)CCCCCCCCCCCCCCCNAPeptideNaturalin vitro activates NodPGLYRP-2Peptidoglycan Recognition Receptor (PGRPs)Miceintraepithelial T lymphocytesintracellular receptorsQ9JLF7.fastaQ9JLF7859recognises peptidoglycan of bacterial cell wallNA247793902014Pubchem_assay
PRRID_1496muramyl tripeptide

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Mycobacteria (Bacteria)CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)C(C)NC(=O)CCC(C(=O)N)NC(=O)C(C)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C)OC(=O)CCCCCCCCCCCCCCCNAPeptideNaturalin vitro activates NodPGLYRP-2Peptidoglycan Recognition Receptor (PGRPs)Humanintraepithelial T lymphocytesintracellular receptorsQ96PD5.fastaQ96PD5576recognises peptidoglycan of bacterial cell wallNA247793902014Pubchem_assay
PRRID_1496muramyl tripeptide

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Mycobacteria (Bacteria)CCCCCCCCCCCCCCCC(=O)OCC(COP(=O)(O)OCCNC(=O)C(C)NC(=O)CCC(C(=O)N)NC(=O)C(C)NC(=O)C(C)OC1C(C(OC(C1O)CO)O)NC(=O)C)OC(=O)CCCCCCCCCCCCCCCNAPeptideNaturalin vitro activates NodPGLYRP-2Peptidoglycan Recognition Receptor (PGRPs)Humanintraepithelial T lymphocytesintracellular receptorsQ96PD5.fastaQ96PD5576recognises peptidoglycan of bacterial cell wallNA247793902014Pubchem_assay
PRRID_1549Peptidoglycan (PGN)

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturaltriggers immune responsesPGN-binding proteins (PGRPs)Peptidoglycan Recognition Receptor (PGRPs)Micelymphocytes, macrophages, dendritic cellsintracellular receptorsNANANAtriggering of these receptors induces activation of the NF-κB pathway and consequently, an immune responseNA247793902014NA
PRRID_1549Peptidoglycan (PGN)

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturaltriggers immune responsesPGN-binding proteins (PGRPs)Peptidoglycan Recognition Receptor (PGRPs)Micelymphocytes, macrophages, dendritic cellsintracellular receptorsNANANAtriggering of these receptors induces activation of the NF-κB pathway and consequently, an immune responseNA247793902014NA
PRRID_1551Peptidoglycan (PGN)

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturaltriggers immune responsesPGN-binding proteins (PGRPs)Peptidoglycan Recognition Receptor (PGRPs)Humanlymphocytes, macrophages, dendritic cellsintracellular receptorsNANANAtriggering of these receptors induces activation of the NF-κB pathway and consequently, an immune responseNA247793902014NA
PRRID_1551Peptidoglycan (PGN)

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturaltriggers immune responsesPGN-binding proteins (PGRPs)Peptidoglycan Recognition Receptor (PGRPs)Humanlymphocytes, macrophages, dendritic cellsintracellular receptorsNANANAtriggering of these receptors induces activation of the NF-κB pathway and consequently, an immune responseNA247793902014NA
PRRID_1564Peptidoglycan (PGN)

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalNAPGN-binding proteins (PGRPs)Peptidoglycan Recognition Receptor (PGRPs)NANANANANANANANA237967912014NA
PRRID_1564Peptidoglycan (PGN)

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalNAPGN-binding proteins (PGRPs)Peptidoglycan Recognition Receptor (PGRPs)NANANANANANANANA237967912014NA
PRRID_1748GroEL

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Pseudomonas aeruginosa (Bacteria)DPTKVTRTALQNAASIAGLMITTEAMVAEAPKKDEPAMPPGGGMGGMGGMDF52GlycoproteinNaturalBacterial infection and immunostimulantPTX3Peptidoglycan Recognition Receptor (PGRPs)HumanMonocytesNAP26022.fastaP26022381NANA280312622016Pubchem_assay
PRRID_1748GroEL

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Pseudomonas aeruginosa (Bacteria)DPTKVTRTALQNAASIAGLMITTEAMVAEAPKKDEPAMPPGGGMGGMGGMDF52GlycoproteinNaturalBacterial infection and immunostimulantPTX3Peptidoglycan Recognition Receptor (PGRPs)HumanMonocytesNAP26022.fastaP26022381NANA280312622016Pubchem_assay
PRRID_1783Lipopolysaccharide (LPS)

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Gram-negative bacteria Escherichia coli, Vibrio anguillarumCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalBacterial infection and immunostimulantCgPGRPS2Peptidoglycan Recognition Receptor (PGRPs)Crassostrea gigasCytoplasmone typical PGRP/amidase domainNANANAActivate NF-kBPAMPs binding assay280420812016NA
PRRID_1783Lipopolysaccharide (LPS)

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Gram-negative bacteria Escherichia coli, Vibrio anguillarumCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalBacterial infection and immunostimulantCgPGRPS2Peptidoglycan Recognition Receptor (PGRPs)Crassostrea gigasCytoplasmone typical PGRP/amidase domainNANANAActivate NF-kBPAMPs binding assay280420812016NA
PRRID_1784Peptidoglycan (PGN)

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Gram-negative bacteria Escherichia coli, Vibrio anguillarumCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalBacterial infection and immunostimulantCgPGRPS2Peptidoglycan Recognition Receptor (PGRPs)Crassostrea gigasCytoplasmone typical PGRP/amidase domainNANANAActivate NF-kBPAMPs binding assay280420812016NA
PRRID_1784Peptidoglycan (PGN)

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Gram-negative bacteria Escherichia coli, Vibrio anguillarumCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalBacterial infection and immunostimulantCgPGRPS2Peptidoglycan Recognition Receptor (PGRPs)Crassostrea gigasCytoplasmone typical PGRP/amidase domainNANANAActivate NF-kBPAMPs binding assay280420812016NA
PRRID_1785Mannan

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Gram-negative bacteria Escherichia coli, Vibrio anguillarumCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNAPolysaccharidesNaturalBacterial infection and immunostimulantCgPGRPS2Peptidoglycan Recognition Receptor (PGRPs)Crassostrea gigasCytoplasmone typical PGRP/amidase domainNANANAActivate NF-kBPAMPs binding assay280420812016NA
PRRID_1785Mannan

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Gram-negative bacteria Escherichia coli, Vibrio anguillarumCCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNAPolysaccharidesNaturalBacterial infection and immunostimulantCgPGRPS2Peptidoglycan Recognition Receptor (PGRPs)Crassostrea gigasCytoplasmone typical PGRP/amidase domainNANANAActivate NF-kBPAMPs binding assay280420812016NA
PRRID_1786Lipopolysaccharide (LPS)

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Gram positive bacteria, Staphylococcus aureus and fungi Yarrowia lipolytica (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalBacterial infection and immunostimulantCgPGRPS2Peptidoglycan Recognition Receptor (PGRPs)Crassostrea gigasCytoplasmone typical PGRP/amidase domainNANANAActivate NF-kBPAMPs binding assay280420812016NA
PRRID_1786Lipopolysaccharide (LPS)

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Gram positive bacteria, Staphylococcus aureus and fungi Yarrowia lipolytica (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNALipopolysaccharide (LPS)NaturalBacterial infection and immunostimulantCgPGRPS2Peptidoglycan Recognition Receptor (PGRPs)Crassostrea gigasCytoplasmone typical PGRP/amidase domainNANANAActivate NF-kBPAMPs binding assay280420812016NA
PRRID_1787Peptidoglycan (PGN)

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Gram positive bacteria, Staphylococcus aureus and fungi Yarrowia lipolytica (Bacteria)CC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalBacterial infection and immunostimulantCgPGRPS2Peptidoglycan Recognition Receptor (PGRPs)Crassostrea gigasCytoplasmone typical PGRP/amidase domainNANANAActivate NF-kBPAMPs binding assay280420812016NA
PRRID_1787Peptidoglycan (PGN)

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Gram positive bacteria, Staphylococcus aureus and fungi Yarrowia lipolytica (Bacteria)CC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalBacterial infection and immunostimulantCgPGRPS2Peptidoglycan Recognition Receptor (PGRPs)Crassostrea gigasCytoplasmone typical PGRP/amidase domainNANANAActivate NF-kBPAMPs binding assay280420812016NA
PRRID_1788Mannan

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Gram positive bacteria, Staphylococcus aureus and fungi Yarrowia lipolytica (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNAPolysaccharidesNaturalBacterial infection and immunostimulantCgPGRPS2Peptidoglycan Recognition Receptor (PGRPs)Crassostrea gigasCytoplasmone typical PGRP/amidase domainNANANAActivate NF-kBPAMPs binding assay280420812016NA
PRRID_1788Mannan

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Gram positive bacteria, Staphylococcus aureus and fungi Yarrowia lipolytica (Bacteria)CCCCCCCCCCCCCC(=O)OC(CCCCCCCCCCC)CC(=O)OC1C(C(OC(C1OP(=O)(O)O)CO)OCC2C(C(C(C(O2)OP(=O)(O)O)NC(=O)CC(CCCCCCCCCCC)O)OC(=O)CC(CCCCCCCCCCC)O)O)NC(=O)CC(CCCCCCCCCCC)OC(=O)CCCCCCCCCCCNAPolysaccharidesNaturalBacterial infection and immunostimulantCgPGRPS2Peptidoglycan Recognition Receptor (PGRPs)Crassostrea gigasCytoplasmone typical PGRP/amidase domainNANANAActivate NF-kBPAMPs binding assay280420812016NA
PRRID_1826NA

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V. anguillarum (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantSmPGRP2Peptidoglycan Recognition Receptor (PGRPs)Scophthalmus maximus liver, spleen, and head-kidney,intestine, gill and skinNANANANAActivate NF-KBqRT-PCR274614222016NA
PRRID_1826NA

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V. anguillarum (Bacteria)NANAPattern-associated molecular patterns (PAMPs)NaturalImmunostimulantSmPGRP2Peptidoglycan Recognition Receptor (PGRPs)Scophthalmus maximus liver, spleen, and head-kidney,intestine, gill and skinNANANANAActivate NF-KBqRT-PCR274614222016NA
PRRID_1839Peptidoglycan (PGN)

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalBacterial infectionCgPGRPS4Peptidoglycan Recognition Receptor (PGRPs)Crassostrea gigasCytoplasmone typical PGRP/amidase domainNANANAActivate NF-kBPAMPs binding assay280420812016NA
PRRID_1839Peptidoglycan (PGN)

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BacteriaCC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAPeptidoglycanNaturalBacterial infectionCgPGRPS4Peptidoglycan Recognition Receptor (PGRPs)Crassostrea gigasCytoplasmone typical PGRP/amidase domainNANANAActivate NF-kBPAMPs binding assay280420812016NA
PRRID_2015E. tarda

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Gram negative Bacteria (Bacteria)NANANANaturalinfectionAdPGRP-S1Peptidoglycan Recognition Receptor (PGRPs)Chinese giant salamander (Andrias davidianus)intestine and skinPGRP domainNANANANAAntibacterial activity assay292459042017NA
PRRID_2015E. tarda

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Gram negative Bacteria (Bacteria)NANANANaturalinfectionAdPGRP-S1Peptidoglycan Recognition Receptor (PGRPs)Chinese giant salamander (Andrias davidianus)intestine and skinPGRP domainNANANANAAntibacterial activity assay292459042017NA
PRRID_2707Lys-type

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Gram-negative E. Coli and L. anguillarum, as well as Gram-positive M.NANAProteinNaturalNArSgPGRP-S1Peptidoglycan Recognition Receptor (PGRPs)NANANANANANANANA292084952018NA
PRRID_2707Lys-type

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Gram-negative E. Coli and L. anguillarum, as well as Gram-positive M.NANAProteinNaturalNArSgPGRP-S1Peptidoglycan Recognition Receptor (PGRPs)NANANANANANANANA292084952018NA
PRRID_2739 Dap-type PGN

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Gram-negative E. Coli and L. anguillarum, as well as Gram-positive M.CC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAProteinNaturalNArSgPGRP-S1Peptidoglycan Recognition Receptor (PGRPs)NANANANANANANANA292084952018NA
PRRID_2739 Dap-type PGN

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Gram-negative E. Coli and L. anguillarum, as well as Gram-positive M.CC(C(=O)O)OC1C(C(OC(C1O)CO)O)NNAProteinNaturalNArSgPGRP-S1Peptidoglycan Recognition Receptor (PGRPs)NANANANANANANANA292084952018NA