PRRDB 2.0 : Pattern Recognition Receptor Database

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    • Basic Search
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  • Browse
    • By Receptor
    • By Ligands
    • By Receptor's source
    • By Ligand's source
    • By Receptor's Structure
      • Available Structures
        • C-Type Lectins (CTLs/CLRs)
        • Gram negative binding Proteins(GNBPs)
        • 1,3-β-D-Glucan Pattern Recognition Protein(GRPs)
        • Lectins
        • Mannose Receptors (MRs)
        • Nod like Receptors (NLRs)
        • Peptidoglycan Recognition Proteins (PGRPs)
        • Rig like Receptor (RLRs)
        • Scavenger receptors (SRs)
        • Toll like Receptors (TLRs)
        • Others
      • Predicted Structures
  • Tools
    • Blast Search
    • Smith-waterman
  • Information
    • Other Resources
    • Statistics
    • Data Submission
    • Acknowledgment
    • Help
  • Developers
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  • Welcome to PRRDB 2.0

    *** Reference: Kaur et al., (2019) PRRDB 2.0: a comprehensive database of pattern-recognition receptors and their ligands. Database, Volume 2019, baz076 ***

    PRRDB2.0 is a comprehensive database of pattern recognition receptors and their ligands. This is an updated version of the database PRRDB. It contains extensive information about 467 unique pattern-recognition receptors and 827 ligands manually extracted from ~600 research articles. This is a manually curated database where information about PRRs and their ligands is extracted manually from research articles and public databases.

    • About PRRDB 2.0

    Aim and Objective: The main aim of this database is to serve the academic community working in field of immunology (mainly subunit vaccine designing). This is a comprehensive database which provides information about most of the Pattern Recognition receptors and their ligands reported in literature. This information is essential as these ligands can be used as adjuvants along with the peptide vaccines to enhance their efficacy.

    Search Options: The database offers i) Basic Search which allows the user to search in any field or against multiple fields. By default, it searches against major fields. It also allows the user to DISPLAY desired fields of the database. ii) Advanced Search which facilitates user to search PRRDB2.0 using multiple queries joined by logical operators like AND/OR/NOT. This search module allows user to perform search on any or all fields of PRRDB2.0. It also allows to DISPLAY all field or user selected fields.

    Browse: Modules under this section allow the users to retrieve data in a classified manner. These modules allow users to browse pattern receptors with respect to their ligands. It also provides the option to browse by receptor's structure.

    Similarity Search: This option allows users to search sequences similar to their query protein against a database of PRR sequences maintained at PRRDB. Smith Waterman is also available for the similarity search by user.

    Mobile Compatible Website: PRRDB 2.0 is built on a responsive template, compatible for desktop, tablet, and smartphone. These templates are dynamic that fit content based on screen size of the device.

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