| Serial No. | ORF | Annotation |
| 1 | YAL001C | TFC3 SGDID:S000000001, Chr I from 151168-151099,151008-147596, reverse complement, Verified ORF, "Largest of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauB domain of TFIIIC that binds DNA at the BoxB promoter sites of tRNA and similar genes; cooperates with Tfc6p in DNA binding" |
| 2 | YAL002W | VPS8 SGDID:S000000002, Chr I from 143709-147533, Verified ORF, "Membrane-associated protein that interacts with Vps21p to facilitate soluble vacuolar protein localization; component of the CORVET complex; required for localization and trafficking of the CPY sorting receptor; contains RING finger motif" |
| 3 | YAL003W | EFB1 SGDID:S000000003, Chr I from 142176-142255,142622-143162, Verified ORF, "Translation elongation factor 1 beta; stimulates nucleotide exchange to regenerate EF-1 alpha-GTP for the next elongation cycle; part of the EF-1 complex, which facilitates binding of aminoacyl-tRNA to the ribosomal A site" |
| 4 | YAL005C | SSA1 SGDID:S000000004, Chr I from 141433-139505, reverse complement, Verified ORF, "ATPase involved in protein folding and nuclear localization signal (NLS)-directed nuclear transport; member of heat shock protein 70 (HSP70) family; forms a chaperone complex with Ydj1p; localized to the nucleus, cytoplasm, and cell wall" |
| 5 | YAL007C | ERP2 SGDID:S000000005, Chr I from 138347-137700, reverse complement, Verified ORF, "Protein that forms a heterotrimeric complex with Erp1p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles" |
| 6 | YAL008W | FUN14 SGDID:S000000006, Chr I from 136916-137512, Verified ORF, "Mitochondrial protein of unknown function" |
| 7 | YAL009W | SPO7 SGDID:S000000007, Chr I from 135856-136635, Verified ORF, "Regulatory subunit of Nem1p-Spo7p phosphatase holoenzyme, which regulates nuclear growth by controlling recruitment of Pah1p onto promoters of phospholipid biosynthetic genes; required for normal nuclear envelope morphology and sporulation" |
| 8 | YAL010C | MDM10 SGDID:S000000008, Chr I from 135667-134186, reverse complement, Verified ORF, "Subunit of both the Mdm10-Mdm12-Mmm1 complex and the mitochondrial sorting and assembly machinery (SAM complex); functions in both the general and Tom40p-specific pathways for import and assembly of outer membrane beta-barrel proteins" |
| 9 | YAL011W | SWC3 SGDID:S000000009, Chr I from 132202-134079, Verified ORF, "Protein of unknown function, component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for formation of nuclear-associated array of smooth endoplasmic reticulum known as karmellae" |
| 10 | YAL012W | CYS3 SGDID:S000000010, Chr I from 130802-131986, Verified ORF, "Cystathionine gamma-lyase, catalyzes one of the two reactions involved in the transsulfuration pathway that yields cysteine from homocysteine with the intermediary formation of cystathionine" |
| 11 | YAL013W | DEP1 SGDID:S000000011, Chr I from 129271-130533, Verified ORF, "Transcriptional modulator involved in regulation of structural phospholipid biosynthesis genes and metabolically unrelated genes, as well as maintenance of telomeres, mating efficiency, and sporulation" |
| 12 | YAL014C | SYN8 SGDID:S000000012, Chr I from 129020-128253, reverse complement, Verified ORF, "Endosomal SNARE related to mammalian syntaxin 8" |
| 13 | YAL015C | NTG1 SGDID:S000000013, Chr I from 128103-126904, reverse complement, Verified ORF, "DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair, localizes to the nucleus and mitochondrion" |
| 14 | YAL016W | TPD3 SGDID:S000000014, Chr I from 124880-126787, Verified ORF, "Regulatory subunit A of the heterotrimeric protein phosphatase 2A, which also contains regulatory subunit Cdc55p and either catalytic subunit Pph21p or Pph22p; required for cell morphogenesis and for transcription by RNA polymerase III" |
| 15 | YAL017W | PSK1 SGDID:S000000015, Chr I from 120226-124296, Verified ORF, "One of two (see also PSK2) PAS domain containing S/T protein kinases; coordinately regulates protein synthesis and carbohydrate metabolism and storage in response to a unknown metabolite that reflects nutritional status" |
| 16 | YAL018C | YAL018C SGDID:S000000016, Chr I from 119542-118565, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 17 | YAL019W | FUN30 SGDID:S000000017, Chr I from 114920-118315, Verified ORF, "Protein whose overexpression affects chromosome stability, potential Cdc28p substrate; homolog of Snf2p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 18 | YAL020C | ATS1 SGDID:S000000018, Chr I from 114616-113615, reverse complement, Verified ORF, "Protein required, with Elongator complex, Kti11p, and Kti12p, for modification of wobble nucleosides in tRNA; has a potential role in regulatory interactions between microtubules and the cell cycle" |
| 19 | YAL021C | CCR4 SGDID:S000000019, Chr I from 113360-110847, reverse complement, Verified ORF, "Component of the CCR4-NOT transcriptional complex, which is involved in regulation of gene expression; component of the major cytoplasmic deadenylase, which is involved in mRNA poly(A) tail shortening" |
| 20 | YAL022C | FUN26 SGDID:S000000020, Chr I from 110431-108878, reverse complement, Verified ORF, "Nucleoside transporter with broad nucleoside selectivity; localized to intracellular membranes" |
| 21 | YAL023C | PMT2 SGDID:S000000021, Chr I from 108552-106273, reverse complement, Verified ORF, "Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt1p, can instead interact with Pmt5p in some conditions; target for new antifungals" |
| 22 | YAL024C | LTE1 SGDID:S000000022, Chr I from 105873-101566, reverse complement, Verified ORF, "Putative GDP/GTP exchange factor required for mitotic exit at low temperatures; acts as a guanine nucleotide exchange factor (GEF) for Tem1p, which is a key regulator of mitotic exit; physically associates with Ras2p-GTP" |
| 23 | YAL025C | MAK16 SGDID:S000000023, Chr I from 101146-100226, reverse complement, Verified ORF, "Essential nuclear protein, constituent of 66S pre-ribosomal particles; required for maturation of 25S and 5.8S rRNAs; required for maintenance of M1 satellite double-stranded RNA of the L-A virus" |
| 24 | YAL026C | DRS2 SGDID:S000000024, Chr I from 99698-95631, reverse complement, Verified ORF, "Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secretory vessicles; contributes to clathrin-coated vesicle formation and endocytosis; mutations in human homolog ATP8B1 result in liver disease" |
| 25 | YAL027W | SAW1 SGDID:S000000025, Chr I from 94688-95473, Verified ORF, "Catalyzes 3'-nonhomologous tail removal of Rad1p/Rad10p-dependent single-strand annealing recombination intermediates; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YAL027W is a non-essential gene" |
| 26 | YAL028W | FRT2 SGDID:S000000026, Chr I from 92901-94487, Verified ORF, "Tail-anchored endoplasmic reticulum membrane protein, interacts with homolog Frt1p but is not a substrate of calcineurin (unlike Frt1p), promotes growth in conditions of high Na+, alkaline pH, or cell wall stress; potential Cdc28p substrate" |
| 27 | YAL029C | MYO4 SGDID:S000000027, Chr I from 92271-87856, reverse complement, Verified ORF, "One of two type V myosin motors (along with MYO2) involved in actin-based transport of cargos; required for mRNA transport, including ASH1 mRNA, and facilitating the growth and movement of ER tubules into the growing bud along with She3p" |
| 28 | YAL030W | SNC1 SGDID:S000000028, Chr I from 87287-87388,87502-87753, Verified ORF, "Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; proposed to be involved in endocytosis; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins" |
| 29 | YAL031C | GIP4 SGDID:S000000029, Chr I from 87032-84750, reverse complement, Verified ORF, "Cytoplasmic Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; potential Cdc28p substrate" |
| 30 | YAL032C | PRP45 SGDID:S000000030, Chr I from 84475-83336, reverse complement, Verified ORF, "Protein required for pre-mRNA splicing; associates with the spliceosome and interacts with splicing factors Prp22p and Prp46p; orthologous to human transcriptional coactivator SKIP and can activate transcription of a reporter gene" |
| 31 | YAL033W | POP5 SGDID:S000000031, Chr I from 82707-83228, Verified ORF, "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" |
| 32 | YAL034C | FUN19 SGDID:S000002134, Chr I from 81952-80711, reverse complement, Verified ORF, "Non-essential protein of unknown function" |
| 33 | YAL034W-A | MTW1 SGDID:S000000032, Chr I from 79719-80588, Verified ORF, "Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; critical to kinetochore assembly" |
| 34 | YAL035W | FUN12 SGDID:S000000033, Chr I from 76428-79436, Verified ORF, "GTPase, required for general translation initiation by promoting Met-tRNAiMet binding to ribosomes and ribosomal subunit joining; homolog of bacterial IF2" |
| 35 | YAL036C | RBG1 SGDID:S000000034, Chr I from 76153-75044, reverse complement, Verified ORF, "Member of the DRG family of GTP-binding proteins; interacts with translating ribosomes and with Tma46p" |
| 36 | YAL037C-A | YAL037C-A SGDID:S000028732, Chr I from 73519-73427, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 37 | YAL037W | YAL037W SGDID:S000000035, Chr I from 74021-74824, Uncharacterized ORF, "Putative protein of unknown function" |
| 38 | YAL038W | CDC19 SGDID:S000000036, Chr I from 71787-73289, Verified ORF, "Pyruvate kinase, functions as a homotetramer in glycolysis to convert phosphoenolpyruvate to pyruvate, the input for aerobic (TCA cycle) or anaerobic (glucose fermentation) respiration" |
| 39 | YAL039C | CYC3 SGDID:S000000037, Chr I from 69526-68717, reverse complement, Verified ORF, "Cytochrome c heme lyase (holocytochrome c synthase), attaches heme to apo-cytochrome c (Cyc1p or Cyc7p) in the mitochondrial intermembrane space; human ortholog may have a role in microphthalmia with linear skin defects (MLS)" |
| 40 | YAL040C | CLN3 SGDID:S000000038, Chr I from 67521-65779, reverse complement, Verified ORF, "G1 cyclin involved in cell cycle progression; activates Cdc28p kinase to promote the G1 to S phase transition; plays a role in regulating transcription of the other G1 cyclins, CLN1 and CLN2; regulated by phosphorylation and proteolysis" |
| 41 | YAL041W | CDC24 SGDID:S000000039, Chr I from 62841-65405, Verified ORF, "Guanine nucleotide exchange factor (GEF or GDP-release factor) for Cdc42p; required for polarity establishment and maintenance, and mutants have morphological defects in bud formation and shmooing" |
| 42 | YAL042W | ERV46 SGDID:S000000040, Chr I from 61317-62564, Verified ORF, "Protein localized to COPII-coated vesicles, forms a complex with Erv41p; involved in the membrane fusion stage of transport" |
| 43 | YAL043C | PTA1 SGDID:S000000041, Chr I from 61053-58696, reverse complement, Verified ORF, "Subunit of holo-CPF, a multiprotein complex and functional homolog of mammalian CPSF, required for the cleavage and polyadenylation of mRNA and snoRNA 3' ends; involved in pre-tRNA processing; binds to the phosphorylated CTD of RNAPII" |
| 44 | YAL044C | GCV3 SGDID:S000000042, Chr I from 58463-57951, reverse complement, Verified ORF, "H subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm" |
| 45 | YAL044W-A | YAL044W-A SGDID:S000007586, Chr I from 57519-57851, Uncharacterized ORF, "Putative protein of unknown function; similar to S. pombe uvi31 which is a putative DNA repair protein" |
| 46 | YAL046C | YAL046C SGDID:S000000044, Chr I from 57386-57030, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; null mutant displays increased frequency of mitochondrial genome loss (petite formation)" |
| 47 | YAL047C | SPC72 SGDID:S000000045, Chr I from 56858-54990, reverse complement, Verified ORF, "Component of the cytoplasmic Tub4p (gamma-tubulin) complex, binds spindle pole bodies and links them to microtubules; has roles in astral microtubule formation and stabilization" |
| 48 | YAL048C | GEM1 SGDID:S000000046, Chr I from 54790-52802, reverse complement, Verified ORF, "Evolutionarily-conserved tail-anchored outer mitochondrial membrane GTPase which regulates mitochondrial morphology; cells lacking Gem1p contain collapsed, globular, or grape-like mitochondria; not required for pheromone-induced cell death" |
| 49 | YAL049C | YAL049C SGDID:S000000047, Chr I from 52596-51856, reverse complement, Uncharacterized ORF, "Cytoplasmic protein of unknown function, potential Hsp82p interactor; null mutant displays decreased frequency of mitochondrial genome loss (petite formation)" |
| 50 | YAL051W | OAF1 SGDID:S000000048, Chr I from 48565-51708, Verified ORF, "Oleate-activated transcription factor, acts alone and as a heterodimer with Pip2p; activates genes involved in beta-oxidation of fatty acids and peroxisome organization and biogenesis" |
| 51 | YAL053W | FLC2 SGDID:S000000049, Chr I from 45900-48251, Verified ORF, "Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance" |
| 52 | YAL054C | ACS1 SGDID:S000000050, Chr I from 45023-42882, reverse complement, Verified ORF, "Acetyl-coA synthetase isoform which, along with Acs2p, is the nuclear source of acetyl-coA for histone acetlyation; expressed during growth on nonfermentable carbon sources and under aerobic conditions" |
| 53 | YAL055W | PEX22 SGDID:S000000051, Chr I from 42178-42720, Verified ORF, "Putative peroxisomal membrane protein required for import of peroxisomal proteins, functionally complements a Pichia pastoris pex22 mutation" |
| 54 | YAL056W | GPB2 SGDID:S000000052, Chr I from 39260-41902, Verified ORF, "Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; homolog of Gpb1p" |
| 55 | YAL058W | CNE1 SGDID:S000000054, Chr I from 37465-38973, Verified ORF, "Calnexin; integral membrane ER chaperone involved in folding and quality control of glycoproteins; chaperone activity is inhibited by Mpd1p, with which Cne1p interacts; 24% identical to mammalian calnexin; Ca+ binding not yet shown in yeast" |
| 56 | YAL059W | ECM1 SGDID:S000000055, Chr I from 36510-37148, Verified ORF, "Protein of unknown function, localized in the nucleoplasm and the nucleolus, genetically interacts with MTR2 in 60S ribosomal protein subunit export" |
| 57 | YAL060W | BDH1 SGDID:S000000056, Chr I from 35156-36304, Verified ORF, "NAD-dependent (R,R)-butanediol dehydrogenase, catalyzes oxidation of (R,R)-2,3-butanediol to (3R)-acetoin, oxidation of meso-butanediol to (3S)-acetoin, and reduction of acetoin; enhances use of 2,3-butanediol as an aerobic carbon source" |
| 58 | YAL061W | BDH2 SGDID:S000000057, Chr I from 33449-34702, Uncharacterized ORF, "Putative medium-chain alcohol dehydrogenase with similarity to BDH1; transcription induced by constitutively active PDR1 and PDR3; BDH2 is an essential gene" |
| 59 | YAL062W | GDH3 SGDID:S000000058, Chr I from 31568-32941, Verified ORF, "NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh1p; expression regulated by nitrogen and carbon sources" |
| 60 | YAL063C | FLO9 SGDID:S000000059, Chr I from 27969-24001, reverse complement, Verified ORF, "Lectin-like protein with similarity to Flo1p, thought to be expressed and involved in flocculation" |
| 61 | YAL063C-A | YAL063C-A SGDID:S000028813, Chr I from 22687-22397, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 62 | YAL064C-A | YAL064C-A SGDID:S000002140, Chr I from 13744-13364, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YAL064C-A is not an essential gene" |
| 63 | YAL064W | YAL064W SGDID:S000000060, Chr I from 21526-21852, Verified ORF, "Protein of unknown function; may interact with ribosomes, based on co-purification experiments" |
| 64 | YAL064W-B | YAL064W-B SGDID:S000002141, Chr I from 12047-12427, Uncharacterized ORF, "Fungal-specific protein of unknown function" |
| 65 | YAL065C | YAL065C SGDID:S000001817, Chr I from 11952-11566, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; has homology to FLO1; possible pseudogene" |
| 66 | YAL067C | SEO1 SGDID:S000000062, Chr I from 9017-7236, reverse complement, Verified ORF, "Putative permease, member of the allantoate transporter subfamily of the major facilitator superfamily; mutation confers resistance to ethionine sulfoxide" |
| 67 | YAL067W-A | YAL067W-A SGDID:S000028593, Chr I from 2480-2707, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 68 | YAL068C | YAL068C SGDID:S000002142, Chr I from 2169-1807, reverse complement, Uncharacterized ORF, "Hypothetical protein" |
| 69 | YAR002C-A | ERP1 SGDID:S000002129, Chr I from 154726-154067, reverse complement, Verified ORF, "Protein that forms a heterotrimeric complex with Erp2p, Emp24p, and Erv25p; member, along with Emp24p and Erv25p, of the p24 family involved in ER to Golgi transport and localized to COPII-coated vesicles" |
| 70 | YAR002W | NUP60 SGDID:S000000063, Chr I from 152259-153878, Verified ORF, "Subunit of the nuclear pore complex (NPC), functions to anchor Nup2p to the NPC in a process controlled by the nucleoplasmic concentration of Gsp1p-GTP; potential Cdc28p substrate; involved in telomere maintenance" |
| 71 | YAR003W | SWD1 SGDID:S000000064, Chr I from 155007-156287, Verified ORF, "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member with similarity to mammalian Rbbp7" |
| 72 | YAR007C | RFA1 SGDID:S000000065, Chr I from 158621-156756, reverse complement, Verified ORF, "Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination" |
| 73 | YAR008W | SEN34 SGDID:S000000066, Chr I from 158967-159794, Verified ORF, "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen34p contains the active site for tRNA 3' splice site cleavage and has similarity to Sen2p and to Archaeal tRNA splicing endonuclease" |
| 74 | YAR009C | YAR009C SGDID:S000000067, Chr I from 164188-160598, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; in YARCTY1-1 TYB is mutant and probably non-functional" |
| 75 | YAR010C | YAR010C SGDID:S000000068, Chr I from 165867-164545, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; in YARCTY1-1 TYB is mutant and probably non-functional" |
| 76 | YAR014C | BUD14 SGDID:S000000069, Chr I from 168866-166743, reverse complement, Verified ORF, "Protein involved in bud-site selection, Bud14p-Glc7p complex functions as a cortical regulator of dynein; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern" |
| 77 | YAR015W | ADE1 SGDID:S000000070, Chr I from 169370-170290, Verified ORF, "N-succinyl-5-aminoimidazole-4-carboxamide ribotide (SAICAR) synthetase, required for 'de novo' purine nucleotide biosynthesis; red pigment accumulates in mutant cells deprived of adenine" |
| 78 | YAR018C | KIN3 SGDID:S000000071, Chr I from 171698-170391, reverse complement, Verified ORF, "Nonessential protein kinase with unknown cellular role" |
| 79 | YAR019C | CDC15 SGDID:S000000072, Chr I from 175133-172209, reverse complement, Verified ORF, "Protein kinase of the Mitotic Exit Network that is localized to the spindle pole bodies at late anaphase; promotes mitotic exit by directly switching on the kinase activity of Dbf2p" |
| 80 | YAR020C | PAU7 SGDID:S000000073, Chr I from 177021-176854, reverse complement, Verified ORF, "Part of 23-member seripauperin multigene family, active during alcoholic fermentation, regulated by anaerobiosis, inhibited by oxygen, repressed by heme" |
| 81 | YAR023C | YAR023C SGDID:S000000074, Chr I from 179818-179279, reverse complement, Uncharacterized ORF, "Putative integral membrane protein, member of DUP240 gene family" |
| 82 | YAR027W | UIP3 SGDID:S000000075, Chr I from 183764-184471, Verified ORF, "Putative integral membrane protein of unknown function; interacts with Ulp1p at the nuclear periphery; member of DUP240 gene family" |
| 83 | YAR028W | YAR028W SGDID:S000000076, Chr I from 184886-185590, Uncharacterized ORF, "Putative integral membrane protein, member of DUP240 gene family; GFP-fusion protein is induced in response to the DNA-damaging agent MMS" |
| 84 | YAR029W | YAR029W SGDID:S000000077, Chr I from 186315-186539, Uncharacterized ORF, "Member of DUP240 gene family but contains no transmembrane domains; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 85 | YAR031W | PRM9 SGDID:S000000078, Chr I from 186830-187726, Verified ORF, "Pheromone-regulated protein with 3 predicted transmembrane segments and an FF sequence, a motif involved in COPII binding; member of DUP240 gene family" |
| 86 | YAR033W | MST28 SGDID:S000000079, Chr I from 188101-188805, Verified ORF, "Putative integral membrane protein, involved in vesicle formation; forms complex with Mst27p; member of DUP240 gene family; binds COPI and COPII vesicles" |
| 87 | YAR035C-A | YAR035C-A SGDID:S000028595, Chr I from 192411-192331, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 88 | YAR035W | YAT1 SGDID:S000000080, Chr I from 190187-192250, Verified ORF, "Outer mitochondrial carnitine acetyltransferase, minor ethanol-inducible enzyme involved in transport of activated acyl groups from the cytoplasm into the mitochondrial matrix; phosphorylated" |
| 89 | YAR042W | SWH1 SGDID:S000000081, Chr I from 192613-196179, Verified ORF, "Protein similar to mammalian oxysterol-binding protein; contains ankyrin repeats; localizes to the Golgi and the nucleus-vacuole junction" |
| 90 | YAR050W | FLO1 SGDID:S000000084, Chr I from 203394-208007, Verified ORF, "Lectin-like protein involved in flocculation, cell wall protein that binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin sensitive and heat resistant; similar to Flo5p" |
| 91 | YAR064W | YAR064W SGDID:S000000089, Chr I from 220189-220488, Uncharacterized ORF, "Putative protein of unknown function" |
| 92 | YAR066W | YAR066W SGDID:S000002144, Chr I from 221040-221651, Uncharacterized ORF, "Putative GPI protein" |
| 93 | YAR068W | YAR068W SGDID:S000000091, Chr I from 222397-222882, Uncharacterized ORF, "Fungal-specific protein of unknown function; induced in respiratory-deficient cells" |
| 94 | YAR071W | PHO11 SGDID:S000000094, Chr I from 225451-226854, Verified ORF, "One of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2" |
| 95 | YBL001C | ECM15 SGDID:S000000097, Chr II from 237469-237155, reverse complement, Verified ORF, "Non-essential protein of unknown function, likely exists as tetramer, may be regulated by the binding of small-molecule ligands (possibly sulfate ions), may have a role in yeast cell-wall biogenesis" |
| 96 | YBL002W | HTB2 SGDID:S000000098, Chr II from 236495-236890, Verified ORF, "One of two nearly identical (see HTB1) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation" |
| 97 | YBL003C | HTA2 SGDID:S000000099, Chr II from 235795-235397, reverse complement, Verified ORF, "One of two nearly identical (see also HTA1) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p" |
| 98 | YBL004W | UTP20 SGDID:S000000100, Chr II from 227639-235120, Verified ORF, "Component of the small-subunit (SSU) processome, which is involved in the biogenesis of the 18S rRNA" |
| 99 | YBL005W | PDR3 SGDID:S000000101, Chr II from 217473-220403, Verified ORF, "Transcriptional activator of the pleiotropic drug resistance network, regulates expression of ATP-binding cassette (ABC) transporters through binding to cis-acting sites known as PDREs (PDR responsive elements)" |
| 100 | YBL005W-A | YBL005W-A SGDID:S000002146, Chr II from 221333-222655, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 101 | YBL005W-B | YBL005W-B SGDID:S000002147, Chr II from 221333-222637,222639-226601, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 102 | YBL006C | LDB7 SGDID:S000000102, Chr II from 217132-216590, reverse complement, Verified ORF, "Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Npl6p, and Htl1p to form a module important for a broad range of RSC functions" |
| 103 | YBL007C | SLA1 SGDID:S000000103, Chr II from 216369-212635, reverse complement, Verified ORF, "Cytoskeletal protein binding protein required for assembly of the cortical actin cytoskeleton; interacts with proteins regulating actin dynamics and proteins required for endocytosis; found in the nucleus and cell cortex; has 3 SH3 domains" |
| 104 | YBL008W | HIR1 SGDID:S000000104, Chr II from 209656-212178, Verified ORF, "Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; contributes to nucleosome formation, heterochromatic gene silencing, and formation of functional kinetochores" |
| 105 | YBL008W-A | YBL008W-A SGDID:S000028529, Chr II from 209412-209651, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 106 | YBL009W | ALK2 SGDID:S000000105, Chr II from 207197-209227, Verified ORF, "Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk1p and to mammalian haspins" |
| 107 | YBL010C | YBL010C SGDID:S000000106, Chr II from 206952-206110, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein colocalizes with clathrin-coated vesicles" |
| 108 | YBL011W | SCT1 SGDID:S000000107, Chr II from 203541-205820, Verified ORF, "Glycerol 3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase of the glycerolipid biosynthesis pathway, prefers 16-carbon fatty acids, similar to Gpt2p, gene is constitutively transcribed" |
| 109 | YBL013W | FMT1 SGDID:S000000109, Chr II from 202059-203264, Verified ORF, "Methionyl-tRNA formyltransferase, catalyzes the formylation of initiator Met-tRNA in mitochondria; potential Cdc28p substrate" |
| 110 | YBL014C | RRN6 SGDID:S000000110, Chr II from 201751-199067, reverse complement, Verified ORF, "Protein involved in the transcription of 35S rRNA genes by RNA polymerase I; component of the core factor (CF) complex also composed of Rrn11p, Rrn7p and TATA-binding protein" |
| 111 | YBL015W | ACH1 SGDID:S000000111, Chr II from 194125-195705, Verified ORF, "Acetyl-coA hydrolase, primarily localized to mitochondria; phosphorylated; required for acetate utilization and for diploid pseudohyphal growth" |
| 112 | YBL016W | FUS3 SGDID:S000000112, Chr II from 192454-193515, Verified ORF, "Mitogen-activated serine/threonine protein kinase involved in mating; phosphoactivated by Ste7p; substrates include Ste12p, Far1p, Bni1p, Sst2p; inhibits invasive growth during mating by phosphorylating Tec1p, promoting its degradation" |
| 113 | YBL017C | PEP1 SGDID:S000000113, Chr II from 191586-186847, reverse complement, Verified ORF, "Type I transmembrane sorting receptor for multiple vacuolar hydrolases; cycles between the late-Golgi and prevacuolar endosome-like compartments" |
| 114 | YBL018C | POP8 SGDID:S000000114, Chr II from 186477-186431,186355-186001, reverse complement, Verified ORF, "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" |
| 115 | YBL019W | APN2 SGDID:S000000115, Chr II from 184356-185918, Verified ORF, "Class II abasic (AP) endonuclease involved in repair of DNA damage; homolog of human HAP1 and E. coli exoIII" |
| 116 | YBL020W | RFT1 SGDID:S000000116, Chr II from 182404-184128, Verified ORF, "Flippase, essential integral membrane protein that is required for translocation of Man5GlcNac2-PP-Dol from the cytoplasmic side to the lumenal side of the ER membrane; mutation is suppressed by expression human p53 protein" |
| 117 | YBL021C | HAP3 SGDID:S000000117, Chr II from 182097-181663, reverse complement, Verified ORF, "Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences contributing to both complex assembly and DNA binding" |
| 118 | YBL022C | PIM1 SGDID:S000000118, Chr II from 181278-177877, reverse complement, Verified ORF, "ATP-dependent Lon protease, involved in degradation of misfolded proteins in mitochondria; required for biogenesis and maintenance of mitochondria" |
| 119 | YBL023C | MCM2 SGDID:S000000119, Chr II from 177529-174923, reverse complement, Verified ORF, "Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex" |
| 120 | YBL024W | NCL1 SGDID:S000000120, Chr II from 172537-174591, Verified ORF, "S-adenosyl-L-methionine-dependent tRNA: m5C-methyltransferase, methylates cytosine to m5C at several positions in tRNAs and intron-containing pre-tRNAs; similar to Nop2p and human proliferation associated nucleolar protein p120" |
| 121 | YBL025W | RRN10 SGDID:S000000121, Chr II from 171484-171921, Verified ORF, "Protein involved in promoting high level transcription of rDNA, subunit of UAF (upstream activation factor) for RNA polymerase I" |
| 122 | YBL026W | LSM2 SGDID:S000000122, Chr II from 170626-170679,170808-171041, Verified ORF, "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" |
| 123 | YBL027W | RPL19B SGDID:S000000123, Chr II from 168426-168427,168812-169379, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl19Ap and has similarity to rat L19 ribosomal protein; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal" |
| 124 | YBL028C | YBL028C SGDID:S000000124, Chr II from 167841-167521, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; predicted to be involved in ribosome biogenesis" |
| 125 | YBL029C-A | YBL029C-A SGDID:S000007591, Chr II from 164775-164491, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; has potential orthologs in Saccharomyces species and in Yarrowia lipolytica" |
| 126 | YBL029W | YBL029W SGDID:S000000125, Chr II from 166137-167267, Uncharacterized ORF, "Non-essential protein of unknown function" |
| 127 | YBL030C | PET9 SGDID:S000000126, Chr II from 164000-163044, reverse complement, Verified ORF, "Major ADP/ATP carrier of the mitochondrial inner membrane, exchanges cytosolic ADP for mitochondrially synthesized ATP; phosphorylated; required for viability in many common lab strains carrying a mutation in the polymorphic SAL1 gene" |
| 128 | YBL031W | SHE1 SGDID:S000000127, Chr II from 161702-162718, Verified ORF, "Cytoskeletal protein of unknown function; overexpression causes growth arrest" |
| 129 | YBL032W | HEK2 SGDID:S000000128, Chr II from 160187-161332, Verified ORF, "RNA binding protein with similarity to hnRNP-K that localizes to the cytoplasm and to subtelomeric DNA; required for the proper localization of ASH1 mRNA; involved in the regulation of telomere position effect and telomere length" |
| 130 | YBL033C | RIB1 SGDID:S000000129, Chr II from 159696-158659, reverse complement, Verified ORF, "GTP cyclohydrolase II; catalyzes the first step of the riboflavin biosynthesis pathway" |
| 131 | YBL034C | STU1 SGDID:S000000130, Chr II from 158392-153851, reverse complement, Verified ORF, "Component of the mitotic spindle that binds to interpolar microtubules via its association with beta-tubulin (Tub2p); required for interpolar microtubules to provide an outward force on the spindle poles" |
| 132 | YBL035C | POL12 SGDID:S000000131, Chr II from 153613-151496, reverse complement, Verified ORF, "B subunit of DNA polymerase alpha-primase complex, required for initiation of DNA replication during mitotic and premeiotic DNA synthesis; also functions in telomere capping and length regulation" |
| 133 | YBL036C | YBL036C SGDID:S000000132, Chr II from 151223-150450, reverse complement, Verified ORF, "Single-domain racemase, possibly non-specific due to the lack of the second domain, which presumably determines specificity; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS" |
| 134 | YBL037W | APL3 SGDID:S000000133, Chr II from 147212-150289, Verified ORF, "Alpha-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport" |
| 135 | YBL038W | MRPL16 SGDID:S000000134, Chr II from 146190-146888, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 136 | YBL039C | URA7 SGDID:S000000135, Chr II from 145731-143992, reverse complement, Verified ORF, "Major CTP synthase isozyme (see also URA8), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis" |
| 137 | YBL039W-B | YBL039W-B SGDID:S000028517, Chr II from 143396-143575, Uncharacterized ORF, "Putative protein of unknown function" |
| 138 | YBL040C | ERD2 SGDID:S000000136, Chr II from 142871-142850,142752-142115, reverse complement, Verified ORF, "HDEL receptor, an integral membrane protein that binds to the HDEL motif in proteins destined for retention in the endoplasmic reticulum; has a role in maintenance of normal levels of ER-resident proteins" |
| 139 | YBL041W | PRE7 SGDID:S000000137, Chr II from 141250-141975, Verified ORF, "Beta 6 subunit of the 20S proteasome" |
| 140 | YBL042C | FUI1 SGDID:S000000138, Chr II from 140263-138344, reverse complement, Verified ORF, "High affinity uridine permease, localized to the plasma membrane; not involved in uracil transport" |
| 141 | YBL043W | ECM13 SGDID:S000000139, Chr II from 136691-137464, Verified ORF, "Non-essential protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation" |
| 142 | YBL044W | YBL044W SGDID:S000000140, Chr II from 136001-136369, Uncharacterized ORF, "Putative protein of unknown function; YBL044W is not an essential protein" |
| 143 | YBL045C | COR1 SGDID:S000000141, Chr II from 135519-134146, reverse complement, Verified ORF, "Core subunit of the ubiquinol-cytochrome c reductase complex (bc1 complex), which is a component of the mitochondrial inner membrane electron transport chain" |
| 144 | YBL046W | PSY4 SGDID:S000000142, Chr II from 132427-133752, Verified ORF, "Putative regulatory subunit of an evolutionarily conserved protein phosphatase complex containing the catalytic subunit Pph3p and a third subunit Psy2p; required for cisplatin resistance; GFP-fusion protein localizes to the nucleus" |
| 145 | YBL047C | EDE1 SGDID:S000000143, Chr II from 132043-127898, reverse complement, Verified ORF, "Key endocytic protein involved in a network of interactions with other endocytic proteins, binds membranes in a ubiquitin-dependent manner, may also bind ubiquitinated membrane-associated proteins" |
| 146 | YBL049W | MOH1 SGDID:S000000145, Chr II from 126831-127247, Verified ORF, "Protein of unknown function, has homology to kinase Snf7p; not required for growth on nonfermentable carbon sources; essential for viability in stationary phase" |
| 147 | YBL050W | SEC17 SGDID:S000000146, Chr II from 125128-125157,125274-126122, Verified ORF, "Peripheral membrane protein required for vesicular transport between ER and Golgi and for the 'priming' step in homotypic vacuole fusion, part of the cis-SNARE complex; has similarity to alpha-SNAP" |
| 148 | YBL051C | PIN4 SGDID:S000000147, Chr II from 124762-122756, reverse complement, Verified ORF, "Protein involved in G2/M phase progression and response to DNA damage, interacts with Rad53p; contains an RNA recognition motif, a nuclear localization signal, and several SQ/TQ cluster domains; hyperphosphorylated in response to DNA damage" |
| 149 | YBL052C | SAS3 SGDID:S000000148, Chr II from 121877-119382, reverse complement, Verified ORF, "Histone acetyltransferase catalytic subunit of NuA3 complex that acetylates histone H3, involved in transcriptional silencing; homolog of the mammalian MOZ proto-oncogene; sas3 gcn5 double mutation confers lethality" |
| 150 | YBL054W | YBL054W SGDID:S000000150, Chr II from 117592-119169, Uncharacterized ORF, "Protein of unknown function involved in rRNA and ribosome biosynthesis" |
| 151 | YBL055C | YBL055C SGDID:S000000151, Chr II from 116832-115576, reverse complement, Verified ORF, "3'-->5' exonuclease and endonuclease with a possible role in apoptosis; has similarity to mammalian and C. elegans apoptotic nucleases" |
| 152 | YBL056W | PTC3 SGDID:S000000152, Chr II from 113765-115171, Verified ORF, "Type 2C protein phosphatase; dephosphorylates Hog1p (see also Ptc2p) to limit maximal kinase activity induced by osmotic stress; dephosphorylates T169 phosphorylated Cdc28p (see also Ptc2p); role in DNA checkpoint inactivation" |
| 153 | YBL057C | PTH2 SGDID:S000000153, Chr II from 113447-112803, reverse complement, Verified ORF, "One of two (see also PTH1) mitochondrially-localized peptidyl-tRNA hydrolases; negatively regulates the ubiquitin-proteasome pathway via interactions with ubiquitin-like ubiquitin-associated proteins; dispensable for cell growth" |
| 154 | YBL058W | SHP1 SGDID:S000000154, Chr II from 111439-112710, Verified ORF, "UBX (ubiquitin regulatory X) domain-containing protein that regulates Glc7p phosphatase activity and interacts with Cdc48p; interacts with ubiquitylated proteins in vivo and is required for degradation of a ubiquitylated model substrate" |
| 155 | YBL059C-A | YBL059C-A SGDID:S000007488, Chr II from 110541-110508,110422-110127, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; contains twin Cx9C motifs that can form coiled coil-helix-coiled-coil helix fold; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
| 156 | YBL059W | YBL059W SGDID:S000000155, Chr II from 110596-110881,110951-111246, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 157 | YBL060W | YEL1 SGDID:S000000156, Chr II from 107934-109997, Uncharacterized ORF, "Guanine nucleotide exchange factor specific for Arf3p; localized to the bud neck and tip; required for localization of Arf3p to the bud neck and tip" |
| 158 | YBL061C | SKT5 SGDID:S000000157, Chr II from 107408-105318, reverse complement, Verified ORF, "Activator of Chs3p (chitin synthase III), recruits Chs3p to the bud neck via interaction with Bni4p; has similarity to Shc1p, which activates Chs3p during sporulation" |
| 159 | YBL063W | KIP1 SGDID:S000000159, Chr II from 101888-105223, Verified ORF, "Kinesin-related motor protein required for mitotic spindle assembly and chromosome segregation; functionally redundant with Cin8p" |
| 160 | YBL064C | PRX1 SGDID:S000000160, Chr II from 101158-100373, reverse complement, Verified ORF, "Mitochondrial peroxiredoxin (1-Cys Prx) with thioredoxin peroxidase activity, has a role in reduction of hydroperoxides; induced during respiratory growth and under conditions of oxidative stress; phosphorylated" |
| 161 | YBL066C | SEF1 SGDID:S000000162, Chr II from 100117-96671, reverse complement, Verified ORF, "Putative transcription factor, has homolog in Kluyveromyces lactis" |
| 162 | YBL067C | UBP13 SGDID:S000000163, Chr II from 95884-93641, reverse complement, Verified ORF, "Putative ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease that cleaves ubiquitin-protein fusions" |
| 163 | YBL068W | PRS4 SGDID:S000000164, Chr II from 92412-93395, Verified ORF, "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes" |
| 164 | YBL069W | AST1 SGDID:S000000165, Chr II from 90739-92028, Verified ORF, "Peripheral membrane protein that interacts with the plasma membrane ATPase Pma1p and has a role in its targeting to the plasma membrane, possibly by influencing its incorporation into lipid rafts" |
| 165 | YBL071C-B | YBL071C-B SGDID:S000028597, Chr II from 89554-89456, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 166 | YBL071W-A | KTI11 SGDID:S000007587, Chr II from 89976-90224, Verified ORF, "Zn-ribbon protein that co-purifies with Dph1, Dph2, Eft2 and Elongator subunits Iki3p, Elp2p, and Elp3p as a complex required for synthesis of diphthamide, a modified histidine residue, and for modification of wobble nucleosides in tRNA" |
| 167 | YBL072C | RPS8A SGDID:S000000168, Chr II from 89123-88521, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; identical to Rps8Bp and has similarity to rat S8 ribosomal protein" |
| 168 | YBL074C | AAR2 SGDID:S000000170, Chr II from 87787-86720, reverse complement, Verified ORF, "Component of the U5 snRNP, required for splicing of U3 precursors; originally described as a splicing factor specifically required for splicing pre-mRNA of the MATa1 cistron" |
| 169 | YBL075C | SSA3 SGDID:S000000171, Chr II from 86446-84497, reverse complement, Verified ORF, "ATPase involved in protein folding and the response to stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm" |
| 170 | YBL076C | ILS1 SGDID:S000000172, Chr II from 84259-81041, reverse complement, Verified ORF, "Cytoplasmic isoleucine-tRNA synthetase, target of the G1-specific inhibitor reveromycin A" |
| 171 | YBL078C | ATG8 SGDID:S000000174, Chr II from 80728-80375, reverse complement, Verified ORF, "Conserved protein that is a component of autophagosomes and Cvt vesicles; undergoes C-terminal conjugation to phosphatidylethanolamine (PE), Atg8p-PE is anchored to membranes and may mediate membrane fusion during autophagosome formation" |
| 172 | YBL079W | NUP170 SGDID:S000000175, Chr II from 75256-79764, Verified ORF, "Abundant subunit of the nuclear pore complex (NPC), required for proper localization of specific nucleoporins within the NPC, involved in nuclear envelope permeability and in chromosome segregation, has similarity to Nup157p" |
| 173 | YBL080C | PET112 SGDID:S000000176, Chr II from 74692-73067, reverse complement, Verified ORF, "Protein required for mitochondrial translation; mutation is functionally complemented by a Bacillus subtilis ortholog" |
| 174 | YBL081W | YBL081W SGDID:S000000177, Chr II from 71863-72969, Uncharacterized ORF, "Non-essential protein of unknown function" |
| 175 | YBL082C | ALG3 SGDID:S000000178, Chr II from 71124-69748, reverse complement, Verified ORF, "Dolichol-P-Man dependent alpha(1-3) mannosyltransferase, involved in the synthesis of dolichol-linked oligosaccharide donor for N-linked glycosylation of proteins" |
| 176 | YBL084C | CDC27 SGDID:S000000180, Chr II from 69442-67166, reverse complement, Verified ORF, "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" |
| 177 | YBL085W | BOI1 SGDID:S000000181, Chr II from 63873-66815, Verified ORF, "Protein implicated in polar growth, functionally redundant with Boi2p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain" |
| 178 | YBL086C | YBL086C SGDID:S000000182, Chr II from 62599-61199, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery" |
| 179 | YBL087C | RPL23A SGDID:S000000183, Chr II from 60735-60694,60189-59818, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, identical to Rpl23Bp and has similarity to E. coli L14 and rat L23 ribosomal proteins" |
| 180 | YBL088C | TEL1 SGDID:S000000184, Chr II from 59379-51016, reverse complement, Verified ORF, "Protein kinase primarily involved in telomere length regulation; contributes to cell cycle checkpoint control in response to DNA damage; functionally redundant with Mec1p; homolog of human ataxia telangiectasia (ATM) gene" |
| 181 | YBL089W | AVT5 SGDID:S000000185, Chr II from 49571-50950, Verified ORF, "Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" |
| 182 | YBL090W | MRP21 SGDID:S000000186, Chr II from 48822-49355, Verified ORF, "Mitochondrial ribosomal protein of the large subunit; MRP21 exhibits genetic interactions with mutations in the COX2 and COX3 mRNA 5'-untranslated leader sequences" |
| 183 | YBL091C | MAP2 SGDID:S000000187, Chr II from 48625-47360, reverse complement, Verified ORF, "Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map1p" |
| 184 | YBL091C-A | SCS22 SGDID:S000007228, Chr II from 47177-47144,47055-46562, reverse complement, Verified ORF, "Protein involved in regulation of phospholipid metabolism; homolog of Scs2p; similar to D. melanogaster inturned protein" |
| 185 | YBL092W | RPL32 SGDID:S000000188, Chr II from 45975-46367, Verified ORF, "Protein component of the large (60S) ribosomal subunit, has similarity to rat L32 ribosomal protein; overexpression disrupts telomeric silencing" |
| 186 | YBL093C | ROX3 SGDID:S000000189, Chr II from 44915-44253, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme" |
| 187 | YBL095W | YBL095W SGDID:S000000191, Chr II from 43274-44086, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 188 | YBL097W | BRN1 SGDID:S000000193, Chr II from 40828-43092, Verified ORF, "Essential protein required for chromosome condensation, likely to function as an intrinsic component of the condensation machinery, may influence multiple aspects of chromosome transmission and dynamics" |
| 189 | YBL098W | BNA4 SGDID:S000000194, Chr II from 39142-40524, Verified ORF, "Kynurenine 3-mono oxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p; putative therapeutic target for Huntington disease" |
| 190 | YBL099W | ATP1 SGDID:S000000195, Chr II from 37050-38687, Verified ORF, "Alpha subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" |
| 191 | YBL100W-A | YBL100W-A SGDID:S000002148, Chr II from 29932-31248, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 192 | YBL100W-B | YBL100W-B SGDID:S000002149, Chr II from 29932-31224,31226-35245, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 193 | YBL100W-C | YBL100W-C SGDID:S000028598, Chr II from 28427-28546, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 194 | YBL101C | ECM21 SGDID:S000000197, Chr II from 28299-24946, reverse complement, Verified ORF, "Non-essential protein of unknown function; promoter contains several Gcn4p binding elements" |
| 195 | YBL102W | SFT2 SGDID:S000000198, Chr II from 24098-24745, Verified ORF, "Non-essential tetra-spanning membrane protein found mostly in the late Golgi, can suppress some sed5 alleles; may be part of the transport machinery, but precise function is unknown; similar to mammalian syntaxin 5" |
| 196 | YBL103C | RTG3 SGDID:S000000199, Chr II from 23535-22075, reverse complement, Verified ORF, "Basic helix-loop-helix-leucine zipper (bHLH/Zip) transcription factor that forms a complex with another bHLH/Zip protein, Rtg1p, to activate the retrograde (RTG) and TOR pathways" |
| 197 | YBL104C | YBL104C SGDID:S000000200, Chr II from 21293-18177, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, promoter contains multiple GCN4 binding sites" |
| 198 | YBL105C | PKC1 SGDID:S000000201, Chr II from 17696-14241, reverse complement, Verified ORF, "Protein serine/threonine kinase essential for cell wall remodeling during growth; localized to sites of polarized growth and the mother-daughter bud neck; homolog of the alpha, beta, and gamma isoforms of mammalian protein kinase C (PKC)" |
| 199 | YBL106C | SRO77 SGDID:S000000202, Chr II from 13879-10847, reverse complement, Verified ORF, "Protein with roles in exocytosis and cation homeostasis; functions in docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro7p and Drosophila lethal giant larvae tumor suppressor; interacts with SNARE protein Sec9p" |
| 200 | YBL107C | YBL107C SGDID:S000000203, Chr II from 10551-9961, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YBL107C is not an essential gene" |
| 201 | YBL108C-A | YBL108C-A SGDID:S000007592, Chr II from 7733-7605, reverse complement, Uncharacterized ORF, "Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36." |
| 202 | YBL111C | YBL111C SGDID:S000002151, Chr II from 5009-4216,4116-2907, reverse complement, Uncharacterized ORF, "Helicase-like protein encoded within the telomeric Y' element" |
| 203 | YBL112C | YBL112C SGDID:S000002152, Chr II from 2899-2582, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YBL112C is contained within TEL02L" |
| 204 | YBL113C | YBL113C SGDID:S000002153, Chr II from 2658-280, reverse complement, Uncharacterized ORF, "Helicase-like protein encoded within the telomeric Y' element" |
| 205 | YBR001C | NTH2 SGDID:S000000205, Chr II from 241285-238943, reverse complement, Verified ORF, "Putative neutral trehalase, required for thermotolerance and may mediate resistance to other cellular stresses" |
| 206 | YBR002C | RER2 SGDID:S000000206, Chr II from 242570-241710, reverse complement, Verified ORF, "Cis-prenyltransferase involved in dolichol synthesis; participates in endoplasmic reticulum (ER) protein sorting" |
| 207 | YBR003W | COQ1 SGDID:S000000207, Chr II from 242811-244232, Verified ORF, "Hexaprenyl pyrophosphate synthetase, catalyzes the first step in ubiquinone (coenzyme Q) biosynthesis" |
| 208 | YBR004C | GPI18 SGDID:S000000208, Chr II from 245669-244368, reverse complement, Verified ORF, "Functional ortholog of human PIG-V, which is a mannosyltransferase that transfers the second mannose in glycosylphosphatidylinositol biosynthesis; the authentic, non-tagged protein was localized to mitochondria" |
| 209 | YBR005W | RCR1 SGDID:S000000209, Chr II from 245908-246549, Verified ORF, "Protein of the ER membrane involved in cell wall chitin deposition; may function in the endosomal-vacuolar trafficking pathway, helping determine whether plasma membrane proteins are degraded or routed to the plasma membrane" |
| 210 | YBR006W | UGA2 SGDID:S000000210, Chr II from 247012-248505, Verified ORF, "Succinate semialdehyde dehydrogenase involved in the utilization of gamma-aminobutyrate (GABA) as a nitrogen source; part of the 4-aminobutyrate and glutamate degradation pathways; localized to the cytoplasm" |
| 211 | YBR007C | DSF2 SGDID:S000000211, Chr II from 251017-248807, reverse complement, Uncharacterized ORF, "Deletion suppressor of mpt5 mutation" |
| 212 | YBR008C | FLR1 SGDID:S000000212, Chr II from 254210-252564, reverse complement, Verified ORF, "Plasma membrane multidrug transporter of the major facilitator superfamily, involved in efflux of fluconazole, diazaborine, benomyl, methotrexate, and other drugs" |
| 213 | YBR009C | HHF1 SGDID:S000000213, Chr II from 255682-255371, reverse complement, Verified ORF, "One of two identical histone H4 proteins (see also HHF2); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity" |
| 214 | YBR010W | HHT1 SGDID:S000000214, Chr II from 256329-256739, Verified ORF, "One of two identical histone H3 proteins (see also HHT2); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation" |
| 215 | YBR011C | IPP1 SGDID:S000000215, Chr II from 257973-257110, reverse complement, Verified ORF, "Cytoplasmic inorganic pyrophosphatase (PPase), catalyzes the rapid exchange of oxygens from Pi with water, highly expressed and essential for viability, active-site residues show identity to those from E. coli PPase" |
| 216 | YBR012W-A | YBR012W-A SGDID:S000002154, Chr II from 259867-261189, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 217 | YBR012W-B | YBR012W-B SGDID:S000002155, Chr II from 259867-261171,261173-265138, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 218 | YBR013C | YBR013C SGDID:S000000217, Chr II from 265879-265490, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, haploid deletion mutant exhibits synthetic phenotype with alpha-synuclein" |
| 219 | YBR014C | GRX7 SGDID:S000000218, Chr II from 267336-266725, reverse complement, Verified ORF, "Cis-golgi localized monothiol glutaredoxin; more similar in activity to dithiol than other monothiol glutaredoxins; involved in the oxidative stress response; does not bind metal ions; functional overlap with GRX6" |
| 220 | YBR015C | MNN2 SGDID:S000000219, Chr II from 269503-267710, reverse complement, Verified ORF, "Alpha-1,2-mannosyltransferase, responsible for addition of the first alpha-1,2-linked mannose to form the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment" |
| 221 | YBR016W | YBR016W SGDID:S000000220, Chr II from 270247-270633, Uncharacterized ORF, "Plasma membrane protein of unknown function; has similarity to hydrophilins, which are hydrophilic, glycine-rich proteins involved in the adaptive response to hyperosmotic conditions" |
| 222 | YBR017C | KAP104 SGDID:S000000221, Chr II from 273703-270947, reverse complement, Verified ORF, "Transportin, cytosolic karyopherin beta 2 involved in delivery of heterogeneous nuclear ribonucleoproteins to the nucleoplasm, binds rg-nuclear localization signals on Nab2p and Hrp1p, plays a role in cell-cycle progression" |
| 223 | YBR018C | GAL7 SGDID:S000000222, Chr II from 275527-274427, reverse complement, Verified ORF, "Galactose-1-phosphate uridyl transferase, synthesizes glucose-1-phosphate and UDP-galactose from UDP-D-glucose and alpha-D-galactose-1-phosphate in the second step of galactose catabolism" |
| 224 | YBR019C | GAL10 SGDID:S000000223, Chr II from 278352-276253, reverse complement, Verified ORF, "UDP-glucose-4-epimerase, catalyzes the interconversion of UDP-galactose and UDP-D-glucose in galactose metabolism; also catalyzes the conversion of alpha-D-glucose or alpha-D-galactose to their beta-anomers" |
| 225 | YBR020W | GAL1 SGDID:S000000224, Chr II from 279021-280607, Verified ORF, "Galactokinase, phosphorylates alpha-D-galactose to alpha-D-galactose-1-phosphate in the first step of galactose catabolism; expression regulated by Gal4p" |
| 226 | YBR021W | FUR4 SGDID:S000000225, Chr II from 281443-283344, Verified ORF, "Uracil permease, localized to the plasma membrane; expression is tightly regulated by uracil levels and environmental cues" |
| 227 | YBR022W | POA1 SGDID:S000000226, Chr II from 283738-284271, Verified ORF, "Phosphatase that is highly specific for ADP-ribose 1''-phosphate, a tRNA splicing metabolite; may have a role in regulation of tRNA splicing" |
| 228 | YBR023C | CHS3 SGDID:S000000227, Chr II from 287925-284428, reverse complement, Verified ORF, "Chitin synthase III, catalyzes the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for synthesis of the majority of cell wall chitin, the chitin ring during bud emergence, and spore wall chitosan" |
| 229 | YBR024W | SCO2 SGDID:S000000228, Chr II from 289445-290350, Verified ORF, "Protein anchored to the mitochondrial inner membrane, similar to Sco1p and may have a redundant function with Sco1p in delivery of copper to cytochrome c oxidase; interacts with Cox2p" |
| 230 | YBR025C | OLA1 SGDID:S000000229, Chr II from 291865-290681, reverse complement, Verified ORF, "P-loop ATPase with similarity to human OLA1 and bacterial YchF; identified as specifically interacting with the proteasome; protein levels are induced by hydrogen peroxide" |
| 231 | YBR026C | ETR1 SGDID:S000000230, Chr II from 294019-292877, reverse complement, Verified ORF, "2-enoyl thioester reductase, member of the medium chain dehydrogenase/reductase family; localized to in mitochondria, where it has a probable role in fatty acid synthesis" |
| 232 | YBR028C | YBR028C SGDID:S000000232, Chr II from 296002-294425, reverse complement, Uncharacterized ORF, "Putative protein kinase, possible substrate of cAMP-dependent protein kinase (PKA)" |
| 233 | YBR029C | CDS1 SGDID:S000000233, Chr II from 297742-296369, reverse complement, Verified ORF, "Phosphatidate cytidylyltransferase (CDP-diglyceride synthetase); an enzyme that catalyzes that conversion of CTP + phosphate into diphosphate + CDP-diaclglyerol, a critical step in the synthesis of all major yeast phospholipids" |
| 234 | YBR030W | YBR030W SGDID:S000000234, Chr II from 298292-299950, Uncharacterized ORF, "Putative protein of unknown function; predicted protein contains a SET domain (S-adenosyl-L-methionine-binding fold)" |
| 235 | YBR031W | RPL4A SGDID:S000000235, Chr II from 300166-301254, Verified ORF, "N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl4Bp and has similarity to E. coli L4 and rat L4 ribosomal proteins" |
| 236 | YBR033W | EDS1 SGDID:S000000237, Chr II from 301944-304703, Uncharacterized ORF, "Putative zinc cluster protein; YBR033W is not an essential gene" |
| 237 | YBR034C | HMT1 SGDID:S000000238, Chr II from 305976-304930, reverse complement, Verified ORF, "Nuclear SAM-dependent mono- and asymmetric arginine dimethylating methyltransferase that modifies hnRNPs, including Npl3p and Hrp1p, thus facilitating nuclear export of these proteins; required for viability of npl3 mutants" |
| 238 | YBR035C | PDX3 SGDID:S000000239, Chr II from 306955-306269, reverse complement, Verified ORF, "Pyridoxine (pyridoxamine) phosphate oxidase, has homologs in E. coli and Myxococcus xanthus; transcription is under the general control of nitrogen metabolism" |
| 239 | YBR036C | CSG2 SGDID:S000000240, Chr II from 310313-309081, reverse complement, Verified ORF, "Endoplasmic reticulum membrane protein, required for mannosylation of inositolphosphorylceramide and for growth at high calcium concentrations" |
| 240 | YBR037C | SCO1 SGDID:S000000241, Chr II from 311451-310564, reverse complement, Verified ORF, "Copper-binding protein of the mitochondrial inner membrane, required for cytochrome c oxidase activity and respiration; may function to deliver copper to cytochrome c oxidase; has similarity to thioredoxins" |
| 241 | YBR038W | CHS2 SGDID:S000000242, Chr II from 311897-314788, Verified ORF, "Chitin synthase II, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for the synthesis of chitin in the primary septum during cytokinesis" |
| 242 | YBR039W | ATP3 SGDID:S000000243, Chr II from 315575-316510, Verified ORF, "Gamma subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" |
| 243 | YBR040W | FIG1 SGDID:S000000244, Chr II from 316968-317864, Verified ORF, "Integral membrane protein required for efficient mating; may participate in or regulate the low affinity Ca2+ influx system, which affects intracellular signaling and cell-cell fusion during mating" |
| 244 | YBR041W | FAT1 SGDID:S000000245, Chr II from 318266-320275, Verified ORF, "Fatty acid transporter and very long-chain fatty acyl-CoA synthetase, may form a complex with Faa1p or Faa4p that imports and activates exogenous fatty acids" |
| 245 | YBR042C | CST26 SGDID:S000000246, Chr II from 321609-320416, reverse complement, Verified ORF, "Protein of unknown function, affects chromosome stability when overexpressed" |
| 246 | YBR043C | QDR3 SGDID:S000000247, Chr II from 323945-321876, reverse complement, Verified ORF, "Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin" |
| 247 | YBR044C | TCM62 SGDID:S000000248, Chr II from 326058-324337, reverse complement, Verified ORF, "Protein involved in the assembly of the mitochondrial succinate dehydrogenase complex; putative chaperone" |
| 248 | YBR045C | GIP1 SGDID:S000000249, Chr II from 330090-328369, reverse complement, Verified ORF, "Meiosis-specific regulatory subunit of the Glc7p protein phosphatase, regulates spore wall formation and septin organization, required for expression of some late meiotic genes and for normal localization of Glc7p" |
| 249 | YBR046C | ZTA1 SGDID:S000000250, Chr II from 331509-330505, reverse complement, Verified ORF, "Zeta-crystallin homolog, found in the cytoplasm and nucleus; has similarity to E. coli quinone oxidoreductase and to human zeta-crystallin, which has quinone oxidoreductase activity" |
| 250 | YBR047W | YBR047W SGDID:S000000251, Chr II from 331831-332358, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 251 | YBR048W | RPS11B SGDID:S000000252, Chr II from 332829-332873,333385-333810, Verified ORF, "Protein component of the small (40S) ribosomal subunit; identical to Rps11Ap and has similarity to E. coli S17 and rat S11 ribosomal proteins" |
| 252 | YBR049C | REB1 SGDID:S000000253, Chr II from 336816-334384, reverse complement, Verified ORF, "RNA polymerase I enhancer binding protein; DNA binding protein which binds to genes transcribed by both RNA polymerase I and RNA polymerase II; required for termination of RNA polymerase I transcription" |
| 253 | YBR050C | REG2 SGDID:S000000254, Chr II from 338197-337181, reverse complement, Verified ORF, "Regulatory subunit of the Glc7p type-1 protein phosphatase; involved with Reg1p, Glc7p, and Snf1p in regulation of glucose-repressible genes, also involved in glucose-induced proteolysis of maltose permease" |
| 254 | YBR052C | RFS1 SGDID:S000000256, Chr II from 339350-338718, reverse complement, Verified ORF, "Protein of unknown function; member of a flavodoxin-like fold protein family that includes Pst2p and Ycp4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 255 | YBR053C | YBR053C SGDID:S000000257, Chr II from 340749-339673, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; induced by cell wall perturbation" |
| 256 | YBR054W | YRO2 SGDID:S000000258, Chr II from 343099-344133, Verified ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; transcriptionally regulated by Haa1p" |
| 257 | YBR055C | PRP6 SGDID:S000000259, Chr II from 347299-344600, reverse complement, Verified ORF, "Splicing factor, component of the U4/U6-U5 snRNP complex" |
| 258 | YBR056W | YBR056W SGDID:S000000260, Chr II from 347877-349382, Uncharacterized ORF, "Putative cytoplasmic protein of unknown function" |
| 259 | YBR057C | MUM2 SGDID:S000000261, Chr II from 353291-352191, reverse complement, Verified ORF, "Cytoplasmic protein essential for meiotic DNA replication and sporulation; interacts with Orc2p, which is a component of the origin recognition complex" |
| 260 | YBR058C | UBP14 SGDID:S000000262, Chr II from 356015-353670, reverse complement, Verified ORF, "Ubiquitin-specific protease that specifically disassembles unanchored ubiquitin chains; involved in fructose-1,6-bisphosphatase (Fbp1p) degradation; similar to human isopeptidase T" |
| 261 | YBR058C-A | TSC3 SGDID:S000007521, Chr II from 356564-356322, reverse complement, Verified ORF, "Protein that stimulates the activity of serine palmitoyltransferase (Lcb1p, Lcb2p) several-fold; involved in sphingolipid biosynthesis" |
| 262 | YBR059C | AKL1 SGDID:S000000263, Chr II from 360185-356859, reverse complement, Verified ORF, "Ser-Thr protein kinase, member (with Ark1p and Prk1p) of the Ark kinase family; involved in endocytosis and actin cytoskeleton organization" |
| 263 | YBR060C | ORC2 SGDID:S000000264, Chr II from 362512-360650, reverse complement, Verified ORF, "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; phosphorylated by Cdc28p" |
| 264 | YBR061C | TRM7 SGDID:S000000265, Chr II from 365717-364785, reverse complement, Verified ORF, "2'-O-ribose methyltransferase, methylates the 2'-O-ribose of nucleotides at positions 32 and 34 of the tRNA anticodon loop" |
| 265 | YBR062C | YBR062C SGDID:S000000266, Chr II from 366598-366583,366500-365974, reverse complement, Uncharacterized ORF, "Hypothetical protein" |
| 266 | YBR063C | YBR063C SGDID:S000000267, Chr II from 368182-366968, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YBR063C is not an essential gene" |
| 267 | YBR065C | ECM2 SGDID:S000000269, Chr II from 369676-368582, reverse complement, Verified ORF, "Pre-mRNA splicing factor, facilitates the cooperative formation of U2/U6 helix II in association with stem II in the spliceosome, function may be regulated by Slu7p" |
| 268 | YBR066C | NRG2 SGDID:S000000270, Chr II from 370697-370035, reverse complement, Verified ORF, "Transcriptional repressor that mediates glucose repression and negatively regulates filamentous growth; has similarity to Nrg1p" |
| 269 | YBR067C | TIP1 SGDID:S000000271, Chr II from 372732-372100, reverse complement, Verified ORF, "Major cell wall mannoprotein with possible lipase activity; transcription is induced by heat- and cold-shock; member of the Srp1p/Tip1p family of serine-alanine-rich proteins" |
| 270 | YBR068C | BAP2 SGDID:S000000272, Chr II from 375687-373858, reverse complement, Verified ORF, "High-affinity leucine permease, functions as a branched-chain amino acid permease involved in the uptake of leucine, isoleucine and valine; contains 12 predicted transmembrane domains" |
| 271 | YBR069C | TAT1 SGDID:S000000273, Chr II from 378430-376571, reverse complement, Verified ORF, "Amino acid transport protein for valine, leucine, isoleucine, and tyrosine, low-affinity tryptophan and histidine transporter; overexpression confers FK506 and FTY720 resistance" |
| 272 | YBR070C | ALG14 SGDID:S000000274, Chr II from 379931-379218, reverse complement, Verified ORF, "Component of UDP-GlcNAc transferase required for the second step of dolichyl-linked oligosaccharide synthesis; anchors the catalytic subunit Alg13p to the ER membrane; similar to bacterial and human glycosyltransferases" |
| 273 | YBR071W | YBR071W SGDID:S000000275, Chr II from 380408-381043, Uncharacterized ORF, "Putative protein of unknown function; (GFP)-fusion and epitope-tagged proteins localize to the cytoplasm; mRNA expression may be regulated by the cell cycle and/or cell wall stress" |
| 274 | YBR072C-A | YBR072C-A SGDID:S000028532, Chr II from 383016-382855, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 275 | YBR072W | HSP26 SGDID:S000000276, Chr II from 382027-382671, Verified ORF, "Small heat shock protein (sHSP) with chaperone activity; forms hollow, sphere-shaped oligomers that suppress unfolded proteins aggregation; oligomer activation requires a heat-induced conformational change; not expressed in unstressed cells" |
| 276 | YBR073W | RDH54 SGDID:S000000277, Chr II from 383209-385983, Verified ORF, "DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in recombinational repair of DNA double-strand breaks during mitosis and meiosis; proposed to be involved in crossover interference" |
| 277 | YBR074W | YBR074W SGDID:S000000278, Chr II from 386281-389211, Uncharacterized ORF, "Putative metalloprotease" |
| 278 | YBR076W | ECM8 SGDID:S000000280, Chr II from 390369-391388, Verified ORF, "Non-essential protein of unknown function" |
| 279 | YBR077C | SLM4 SGDID:S000000281, Chr II from 392287-391799, reverse complement, Verified ORF, "Component of the EGO complex, which is involved in the regulation of microautophagy, and of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; gene exhibits synthetic genetic interaction with MSS4" |
| 280 | YBR078W | ECM33 SGDID:S000000282, Chr II from 393118-393175,393506-394854, Verified ORF, "GPI-anchored protein of unknown function, has a possible role in apical bud growth; GPI-anchoring on the plasma membrane crucial to function; phosphorylated in mitochondria; similar to Sps2p and Pst1p" |
| 281 | YBR079C | RPG1 SGDID:S000000283, Chr II from 398271-395377, reverse complement, Verified ORF, "Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes" |
| 282 | YBR080C | SEC18 SGDID:S000000284, Chr II from 400884-398608, reverse complement, Verified ORF, "ATPase required for the release of Sec17p during the 'priming' step in homotypic vacuole fusion and for ER to Golgi transport; homolog of the mammalian NSF" |
| 283 | YBR081C | SPT7 SGDID:S000000285, Chr II from 405245-401247, reverse complement, Verified ORF, "Subunit of the SAGA transcriptional regulatory complex, involved in proper assembly of the complex; also present as a C-terminally truncated form in the SLIK/SALSA transcriptional regulatory complex" |
| 284 | YBR082C | UBC4 SGDID:S000000286, Chr II from 407163-407117,407021-406622, reverse complement, Verified ORF, "Ubiquitin-conjugating enzyme (E2), mediates degradation of short-lived and abnormal proteins; interacts with E3-CaM in ubiquitinating calmodulin; interacts with many SCF ubiquitin protein ligases; component of the cellular stress response" |
| 285 | YBR083W | TEC1 SGDID:S000000287, Chr II from 409163-410623, Verified ORF, "Transcription factor required for full Ty1 epxression, Ty1-mediated gene activation, and haploid invasive and diploid pseudohyphal growth; TEA/ATTS DNA-binding domain family member" |
| 286 | YBR084C-A | RPL19A SGDID:S000002156, Chr II from 415255-415254,414747-414180, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl19Bp and has similarity to rat L19 ribosomal protein; rpl19a and rpl19b single null mutations result in slow growth, while the double null mutation is lethal" |
| 287 | YBR084W | MIS1 SGDID:S000000288, Chr II from 411048-413975, Verified ORF, "Mitochondrial C1-tetrahydrofolate synthase, involved in interconversion between different oxidation states of tetrahydrofolate (THF); provides activities of formyl-THF synthetase, methenyl-THF cyclohydrolase, and methylene-THF dehydrogenase" |
| 288 | YBR085C-A | YBR085C-A SGDID:S000007522, Chr II from 419158-418901, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus" |
| 289 | YBR085W | AAC3 SGDID:S000000289, Chr II from 415977-416900, Verified ORF, "Mitochondrial inner membrane ADP/ATP translocator, exchanges cytosolic ADP for mitochondrially synthesized ATP; expressed under anaerobic conditions; similar to Pet9p and Aac1p; has roles in maintenance of viability and in respiration" |
| 290 | YBR086C | IST2 SGDID:S000000290, Chr II from 423035-420195, reverse complement, Verified ORF, "Plasma membrane protein that may be involved in osmotolerance, localizes to the mother cell in small-budded cells and to the bud in medium- and large-budded cells; mRNA is transported to the bud tip by an actomyosin-driven process" |
| 291 | YBR087W | RFC5 SGDID:S000000291, Chr II from 423759-424823, Verified ORF, "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon" |
| 292 | YBR088C | POL30 SGDID:S000000292, Chr II from 425760-424984, reverse complement, Verified ORF, "Proliferating cell nuclear antigen (PCNA), functions as the sliding clamp for DNA polymerase delta; may function as a docking site for other proteins required for mitotic and meiotic chromosomal DNA replication and for DNA repair" |
| 293 | YBR089C-A | NHP6B SGDID:S000002157, Chr II from 426483-426184, reverse complement, Verified ORF, "High-mobility group non-histone chromatin protein, functionally redundant with Nhp6Ap; homologous to mammalian high mobility group proteins 1 and 2; acts to recruit transcription factor Rcs1p to certain promoters" |
| 294 | YBR090C | YBR090C SGDID:S000000294, Chr II from 427052-426868,426510-426327, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
| 295 | YBR091C | MRS5 SGDID:S000000295, Chr II from 427478-427149, reverse complement, Verified ORF, "Essential protein of the inner mitochondrial membrane, peripherally localized; component of the TIM22 complex, which is a twin-pore translocase that mediates insertion of numerous multispanning inner membrane proteins" |
| 296 | YBR092C | PHO3 SGDID:S000000296, Chr II from 429095-427692, reverse complement, Verified ORF, "Constitutively expressed acid phosphatase similar to Pho5p; brought to the cell surface by transport vesicles; hydrolyzes thiamin phosphates in the periplasmic space, increasing cellular thiamin uptake; expression is repressed by thiamin" |
| 297 | YBR093C | PHO5 SGDID:S000000297, Chr II from 430945-429542, reverse complement, Verified ORF, "Repressible acid phosphatase (1 of 3) that also mediates extracellular nucleotide-derived phosphate hydrolysis; secretory pathway derived cell surface glycoprotein; induced by phosphate starvation and coordinately regulated by PHO4 and PHO2" |
| 298 | YBR094W | PBY1 SGDID:S000000298, Chr II from 432030-434291, Verified ORF, "Putative tubulin tyrosine ligase associated with P-bodies" |
| 299 | YBR095C | RXT2 SGDID:S000000299, Chr II from 435692-434400, reverse complement, Verified ORF, "Subunit of the histone deacetylase Rpd3L complex; possibly involved in cell fusion and invasive growth" |
| 300 | YBR096W | YBR096W SGDID:S000000300, Chr II from 436015-436707, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER" |
| 301 | YBR097W | VPS15 SGDID:S000000301, Chr II from 436945-441309, Verified ORF, "Myristoylated serine/threonine protein kinase involved in vacuolar protein sorting; functions as a membrane-associated complex with Vps34p; active form recruits Vps34p to the Golgi membrane; interacts with the GDP-bound form of Gpa1p" |
| 302 | YBR098W | MMS4 SGDID:S000000302, Chr II from 441509-443584, Verified ORF, "Subunit of the structure-specific Mms4p-Mus81p endonuclease that cleaves branched DNA; involved in recombination and DNA repair" |
| 303 | YBR101C | FES1 SGDID:S000000305, Chr II from 444687-443815, reverse complement, Verified ORF, "Hsp70 (Ssa1p) nucleotide exchange factor, cytosolic homolog of Sil1p, which is the nucleotide exchange factor for BiP (Kar2p) in the endoplasmic reticulum" |
| 304 | YBR102C | EXO84 SGDID:S000000306, Chr II from 447317-445056, reverse complement, Verified ORF, "Essential protein with dual roles in spliceosome assembly and exocytosis; the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p) mediates polarized targeting of secretory vesicles to active sites of exocytosis" |
| 305 | YBR103W | SIF2 SGDID:S000000307, Chr II from 447703-449310, Verified ORF, "WD40 repeat-containing subunit of the Set3C histone deacetylase complex, which represses early/middle sporulation genes; antagonizes telomeric silencing; binds specifically to the Sir4p N-terminus" |
| 306 | YBR104W | YMC2 SGDID:S000000308, Chr II from 449661-450650, Verified ORF, "Mitochondrial protein, putative inner membrane transporter with a role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; has similarity with Ymc1p" |
| 307 | YBR105C | VID24 SGDID:S000000309, Chr II from 451963-450875, reverse complement, Verified ORF, "Peripheral membrane protein located at Vid (vacuole import and degradation) vesicles; regulates fructose-1,6-bisphosphatase (FBPase) targeting to the vacuole; involved in proteasome-dependent catabolite degradation of FBPase" |
| 308 | YBR106W | PHO88 SGDID:S000000310, Chr II from 452652-453218, Verified ORF, "Probable membrane protein, involved in phosphate transport; pho88 pho86 double null mutant exhibits enhanced synthesis of repressible acid phosphatase at high inorganic phosphate concentrations" |
| 309 | YBR107C | IML3 SGDID:S000000311, Chr II from 454524-453787, reverse complement, Verified ORF, "Protein with a role in kinetochore function, localizes to the outer kinetochore in a Ctf19p-dependent manner, interacts with Chl4p and Ctf19p" |
| 310 | YBR108W | YBR108W SGDID:S000000312, Chr II from 454816-457659, Uncharacterized ORF, "Protein interacting with Rsv167p; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media" |
| 311 | YBR109C | CMD1 SGDID:S000000313, Chr II from 458356-457913, reverse complement, Verified ORF, "Calmodulin; Ca++ binding protein that regulates Ca++ independent processes (mitosis, bud growth, actin organization, endocytosis, etc.) and Ca++ dependent processes (stress-activated pathways), targets include Nuf1p, Myo2p and calcineurin" |
| 312 | YBR110W | ALG1 SGDID:S000000314, Chr II from 458866-460215, Verified ORF, "Mannosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum (ER); essential for viability, mutation is functionally complemented by human ortholog" |
| 313 | YBR111C | YSA1 SGDID:S000000315, Chr II from 461867-461172, reverse complement, Verified ORF, "Nudix hydrolase family member with ADP-ribose pyrophosphatase activity" |
| 314 | YBR111W-A | SUS1 SGDID:S000028510, Chr II from 462133-462203,462284-462423,462494-462573, Verified ORF, "Protein involved in mRNA export coupled transcription activation; component of the SAGA histone acetylase complex" |
| 315 | YBR112C | CYC8 SGDID:S000000316, Chr II from 465764-462864, reverse complement, Verified ORF, "General transcriptional co-repressor, acts together with Tup1p; also acts as part of a transcriptional co-activator complex that recruits the SWI/SNF and SAGA complexes to promoters" |
| 316 | YBR114W | RAD16 SGDID:S000000318, Chr II from 467242-469614, Verified ORF, "Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad7p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex" |
| 317 | YBR115C | LYS2 SGDID:S000000319, Chr II from 473920-469742, reverse complement, Verified ORF, "Alpha aminoadipate reductase, catalyzes the reduction of alpha-aminoadipate to alpha-aminoadipate 6-semialdehyde, which is the fifth step in biosynthesis of lysine; activation requires posttranslational phosphopantetheinylation by Lys5p" |
| 318 | YBR117C | TKL2 SGDID:S000000321, Chr II from 476431-474386, reverse complement, Verified ORF, "Transketolase, similar to Tkl1p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids" |
| 319 | YBR118W | TEF2 SGDID:S000000322, Chr II from 477665-479041, Verified ORF, "Translational elongation factor EF-1 alpha; also encoded by TEF1; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes" |
| 320 | YBR119W | MUD1 SGDID:S000000323, Chr II from 479332-479339,479429-480317, Verified ORF, "U1 snRNP A protein, homolog of human U1-A; involved in nuclear mRNA splicing" |
| 321 | YBR120C | CBP6 SGDID:S000000324, Chr II from 480917-480429, reverse complement, Verified ORF, "Mitochondrial translational activator of the COB mRNA; phosphorylated" |
| 322 | YBR121C | GRS1 SGDID:S000000325, Chr II from 483361-481358, reverse complement, Verified ORF, "Cytoplasmic and mitochondrial glycyl-tRNA synthase that ligates glycine to the cognate anticodon bearing tRNA; transcription termination factor that may interact with the 3'-end of pre-mRNA to promote 3'-end formation" |
| 323 | YBR122C | MRPL36 SGDID:S000000326, Chr II from 484497-483964, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit; overproduction suppresses mutations in the COX2 leader peptide-encoding region" |
| 324 | YBR123C | TFC1 SGDID:S000000327, Chr II from 486685-484736, reverse complement, Verified ORF, "One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes; human homolog is TFIIIC-63" |
| 325 | YBR125C | PTC4 SGDID:S000000329, Chr II from 488374-487193, reverse complement, Verified ORF, "Cytoplasmic type 2C protein phosphatase; identified as a high-copy number suppressor of the synthetic lethality of a cnb1 mpk1 double deletion; overexpression decreases high-osmolarity induced Hog1p phosphorylation and kinase activity" |
| 326 | YBR126C | TPS1 SGDID:S000000330, Chr II from 490386-488899, reverse complement, Verified ORF, "Synthase subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; also found in a monomeric form; expression is induced by the stress response and repressed by the Ras-cAMP pathway" |
| 327 | YBR127C | VMA2 SGDID:S000000331, Chr II from 492816-491263, reverse complement, Verified ORF, "Subunit B of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; contains nucleotide binding sites; also detected in the cytoplasm" |
| 328 | YBR128C | ATG14 SGDID:S000000332, Chr II from 494109-493075, reverse complement, Verified ORF, "Autophagy-specific subunit of phosphatidylinositol 3-kinase complex I (with Vps34p, Vps15p, and Vps30p); Atg14p targets complex I to the pre-autophagosomal structure (PAS); required for localizing additional ATG proteins to the PAS" |
| 329 | YBR129C | OPY1 SGDID:S000000333, Chr II from 495333-494347, reverse complement, Verified ORF, "Protein of unknown function, overproduction blocks cell cycle arrest in the presence of mating pheromone; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 330 | YBR130C | SHE3 SGDID:S000000334, Chr II from 496863-495586, reverse complement, Verified ORF, "Protein that acts as an adaptor between Myo4p and the She2p-mRNA complex; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud; also required for cortical ER inheritance" |
| 331 | YBR131W | CCZ1 SGDID:S000000335, Chr II from 497157-499271, Verified ORF, "Protein involved in vacuolar assembly, essential for autophagy and the cytoplasm-to-vacuole pathway" |
| 332 | YBR132C | AGP2 SGDID:S000000336, Chr II from 501436-499646, reverse complement, Verified ORF, "High affinity polyamine permease, preferentially uses spermidine over putrescine; expression is down-regulated by osmotic stress; plasma membrane carnitine transporter, also functions as a low-affinity amino acid permease" |
| 333 | YBR133C | HSL7 SGDID:S000000337, Chr II from 504281-501798, reverse complement, Verified ORF, "Protein arginine N-methyltransferase that exhibits septin and Hsl1p-dependent bud neck localization and periodic Hsl1p-dependent phosphorylation; required along with Hsl1p for bud neck recruitment, phosphorylation, and degradation of Swe1p" |
| 334 | YBR135W | CKS1 SGDID:S000000339, Chr II from 504848-505300, Verified ORF, "Cyclin-dependent protein kinase regulatory subunit and adaptor; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters" |
| 335 | YBR136W | MEC1 SGDID:S000000340, Chr II from 505662-512768, Verified ORF, "Genome integrity checkpoint protein and PI kinase superfamily member; signal transducer required for cell cycle arrest and transcriptional responses prompted by damaged or unreplicated DNA; monitors and participates in meiotic recombination" |
| 336 | YBR137W | YBR137W SGDID:S000000341, Chr II from 513038-513577, Uncharacterized ORF, "Protein of unknown function; localized to the cytoplasm; binds to Replication Protein A (RPA); YBR137W is not an essential gene" |
| 337 | YBR138C | YBR138C SGDID:S000000342, Chr II from 515330-513756, reverse complement, Uncharacterized ORF, "Cytoplasmic protein of unknown function, potentially phosphorylated by Cdc28p; YBR138C is not an essential gene" |
| 338 | YBR139W | YBR139W SGDID:S000000343, Chr II from 515658-517184, Verified ORF, "Putative serine type carboxypeptidase with a role in phytochelatin synthesis; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression induced by nitrogen limitation in a GLN3, GAT1-independent manner" |
| 339 | YBR140C | IRA1 SGDID:S000000344, Chr II from 526622-517344, reverse complement, Verified ORF, "GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, mediates membrane association of adenylate cyclase" |
| 340 | YBR141C | YBR141C SGDID:S000000345, Chr II from 528032-527019, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YBR141C is not an essential gene" |
| 341 | YBR142W | MAK5 SGDID:S000000346, Chr II from 528311-530632, Verified ORF, "Essential nucleolar protein, putative DEAD-box RNA helicase required for maintenance of M1 dsRNA virus; involved in biogenesis of large (60S) ribosomal subunits" |
| 342 | YBR143C | SUP45 SGDID:S000000347, Chr II from 532176-530863, reverse complement, Verified ORF, "Polypeptide release factor involved in translation termination; mutant form acts as a recessive omnipotent suppressor" |
| 343 | YBR145W | ADH5 SGDID:S000000349, Chr II from 533756-534811, Verified ORF, "Alcohol dehydrogenase isoenzyme V; involved in ethanol production" |
| 344 | YBR146W | MRPS9 SGDID:S000000350, Chr II from 535254-536090, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 345 | YBR147W | YBR147W SGDID:S000000351, Chr II from 536569-537459, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays fluconazole resistance and suppresses cdc13-1 temperature sensitivity" |
| 346 | YBR148W | YSW1 SGDID:S000000352, Chr II from 537870-539699, Verified ORF, "Protein expressed specifically in spores" |
| 347 | YBR149W | ARA1 SGDID:S000000353, Chr II from 539981-541015, Verified ORF, "NADP+ dependent arabinose dehydrogenase, involved in carbohydrate metabolism; purified as homodimer; naturally occurs with a N-terminus degradation product" |
| 348 | YBR150C | TBS1 SGDID:S000000354, Chr II from 544487-541203, reverse complement, Verified ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 349 | YBR151W | APD1 SGDID:S000000355, Chr II from 545022-545972, Verified ORF, "Protein of unknown function, required for normal localization of actin patches and for normal tolerance of sodium ions and hydrogen peroxide; localizes to both cytoplasm and nucleus" |
| 350 | YBR152W | SPP381 SGDID:S000000356, Chr II from 546370-547245, Verified ORF, "mRNA splicing factor, component of U4/U6.U5 tri-snRNP; interacts genetically and physically with Prp38p" |
| 351 | YBR153W | RIB7 SGDID:S000000357, Chr II from 547454-548188, Verified ORF, "Diaminohydroxyphoshoribosylaminopyrimidine deaminase; catalyzes the second step of the riboflavin biosynthesis pathway" |
| 352 | YBR154C | RPB5 SGDID:S000000358, Chr II from 549003-548356, reverse complement, Verified ORF, "RNA polymerase subunit ABC27, common to RNA polymerases I, II, and III; contacts DNA and affects transactivation" |
| 353 | YBR155W | CNS1 SGDID:S000000359, Chr II from 549765-550922, Verified ORF, "TPR-containing co-chaperone; binds both Hsp82p (Hsp90) and Ssa1p (Hsp70) and stimulates the ATPase activity of SSA1, ts mutants reduce Hsp82p function while over expression suppresses the phenotypes of an HSP82 ts allele and a cpr7 deletion" |
| 354 | YBR156C | SLI15 SGDID:S000000360, Chr II from 553194-551098, reverse complement, Verified ORF, "Subunit of the Ipl1p-Sli15p-Bir1p complex that regulates kinetochore-microtubule attachments, activation of the spindle tension checkpoint, and mitotic spindle disassembly; regulates the activity and localization of the Ipl1p aurora kinase" |
| 355 | YBR157C | ICS2 SGDID:S000000361, Chr II from 554304-553537, reverse complement, Verified ORF, "Protein of unknown function; null mutation does not confer any obvious defects in growth, spore germination, viability, or carbohydrate utilization" |
| 356 | YBR158W | AMN1 SGDID:S000000362, Chr II from 556543-558192, Verified ORF, "Protein required for daughter cell separation, multiple mitotic checkpoints, and chromosome stability; contains 12 degenerate leucine-rich repeat motifs; expression is induced by the Mitotic Exit Network (MEN)" |
| 357 | YBR159W | YBR159W SGDID:S000000363, Chr II from 558679-559722, Verified ORF, "Microsomal beta-keto-reductase; contains oleate response element (ORE) sequence in the promoter region; mutants exhibit reduced VLCFA synthesis, accumulate high levels of dihydrosphingosine, phytosphingosine and medium-chain ceramides" |
| 358 | YBR160W | CDC28 SGDID:S000000364, Chr II from 560072-560968, Verified ORF, "Catalytic subunit of the main cell cycle cyclin-dependent kinase (CDK); alternately associates with G1 cyclins (CLNs) and G2/M cyclins (CLBs) which direct the CDK to specific substrates" |
| 359 | YBR161W | CSH1 SGDID:S000000365, Chr II from 561629-562759, Verified ORF, "Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Sur1p" |
| 360 | YBR162C | TOS1 SGDID:S000000366, Chr II from 564565-563198, reverse complement, Verified ORF, "Covalently-bound cell wall protein of unknown function; identified as a cell cycle regulated SBF target gene; deletion mutants are highly resistant to treatment with beta-1,3-glucanase; has sequence similarity to YJL171C" |
| 361 | YBR162W-A | YSY6 SGDID:S000002158, Chr II from 565226-565423, Verified ORF, "Protein whose expression suppresses a secretory pathway mutation in E. coli; has similarity to the mammalian RAMP4 protein involved in secretion" |
| 362 | YBR163W | DEM1 SGDID:S000000367, Chr II from 565718-567475, Verified ORF, "Mitochondrial protein of unknown function; null mutant has defects in cell morphology and in response to air drying; may be regulated by the transcription factor Ace2" |
| 363 | YBR164C | ARL1 SGDID:S000000368, Chr II from 568421-567870, reverse complement, Verified ORF, "Soluble GTPase with a role in regulation of membrane traffic; regulates potassium influx; G protein of the Ras superfamily, similar to ADP-ribosylation factor" |
| 364 | YBR165W | UBS1 SGDID:S000000369, Chr II from 568847-569680, Verified ORF, "Ubiquitin-conjugating enzyme suppressor that functions as a general positive regulator of Cdc34p activity; nuclear protein that may represent a link between nucleocytoplasmic transport and ubiquitin ligase activity" |
| 365 | YBR166C | TYR1 SGDID:S000000370, Chr II from 571195-569837, reverse complement, Verified ORF, "Prephenate dehydrogenase involved in tyrosine biosynthesis, expression is dependent on phenylalanine levels" |
| 366 | YBR167C | POP7 SGDID:S000000371, Chr II from 571885-571463, reverse complement, Verified ORF, "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" |
| 367 | YBR168W | PEX32 SGDID:S000000372, Chr II from 572366-573607, Verified ORF, "Peroxisomal integral membrane protein, involved in negative regulation of peroxisome size; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p" |
| 368 | YBR169C | SSE2 SGDID:S000000373, Chr II from 575991-573910, reverse complement, Verified ORF, "Member of the heat shock protein 70 (HSP70) family; may be involved in protein folding; localized to the cytoplasm; highly homologous to the heat shock protein Sse1p" |
| 369 | YBR170C | NPL4 SGDID:S000000374, Chr II from 578081-576339, reverse complement, Verified ORF, "Endoplasmic reticulum and nuclear membrane protein, forms a complex with Cdc48p and Ufd1p that recognizes ubiquitinated proteins in the endoplasmic reticulum and delivers them to the proteasome for degradation" |
| 370 | YBR171W | SEC66 SGDID:S000000375, Chr II from 578359-578979, Verified ORF, "Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER" |
| 371 | YBR172C | SMY2 SGDID:S000000376, Chr II from 581367-579145, reverse complement, Verified ORF, "Protein of unknown function involved in COPII vesicle formation; interacts with the Sec23p/Sec24p subcomplex; overexpression suppresses the temperature sensitivity of a myo2 mutant; has similarity to S. pombe Mpd2" |
| 372 | YBR173C | UMP1 SGDID:S000000377, Chr II from 582167-581721, reverse complement, Verified ORF, "Short-lived chaperone required for correct maturation of the 20S proteasome; may inhibit premature dimerization of proteasome half-mers; degraded by proteasome upon completion of its assembly" |
| 373 | YBR175W | SWD3 SGDID:S000000379, Chr II from 582403-583350, Verified ORF, "Essential subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; WD40 beta propeller superfamily member and ortholog of mammalian WDR5" |
| 374 | YBR176W | ECM31 SGDID:S000000380, Chr II from 583715-584653, Verified ORF, "Ketopantoate hydroxymethyltransferase, required for pantothenic acid biosynthesis, converts 2-oxoisovalerate into 2-dehydropantoate" |
| 375 | YBR177C | EHT1 SGDID:S000000381, Chr II from 586157-584802, reverse complement, Verified ORF, "Acyl-coenzymeA:ethanol O-acyltransferase that plays a minor role in medium-chain fatty acid ethyl ester biosynthesis; possesses short-chain esterase activity; localizes to lipid particles and the mitochondrial outer membrane" |
| 376 | YBR179C | FZO1 SGDID:S000000383, Chr II from 589109-586542, reverse complement, Verified ORF, "Mitochondrial integral membrane protein involved in mitochondrial fusion and maintenance of the mitochondrial genome; contains N-terminal GTPase domain" |
| 377 | YBR180W | DTR1 SGDID:S000000384, Chr II from 589736-591454, Verified ORF, "Putative dityrosine transporter, required for spore wall synthesis; expressed during sporulation; member of the major facilitator superfamily (DHA1 family) of multidrug resistance transporters" |
| 378 | YBR181C | RPS6B SGDID:S000000385, Chr II from 592769-592764,592411-591707, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; identical to Rps6Ap and has similarity to rat S6 ribosomal protein" |
| 379 | YBR182C | SMP1 SGDID:S000000386, Chr II from 594859-593501, reverse complement, Verified ORF, "Putative transcription factor involved in regulating the response to osmotic stress; member of the MADS-box family of transcription factors" |
| 380 | YBR182C-A | YBR182C-A SGDID:S000028603, Chr II from 595550-595356, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 381 | YBR183W | YPC1 SGDID:S000000387, Chr II from 596110-597060, Verified ORF, "Alkaline ceramidase that also has reverse (CoA-independent) ceramide synthase activity, catalyzes both breakdown and synthesis of phytoceramide; overexpression confers fumonisin B1 resistance" |
| 382 | YBR184W | YBR184W SGDID:S000000388, Chr II from 597358-598929, Uncharacterized ORF, "Putative protein of unknown function; YBR184W is not an essential gene" |
| 383 | YBR185C | MBA1 SGDID:S000000389, Chr II from 599954-599118, reverse complement, Verified ORF, "Protein involved in assembly of mitochondrial respiratory complexes; may act as a receptor for proteins destined for export from the mitochondrial matrix to the inner membrane" |
| 384 | YBR186W | PCH2 SGDID:S000000390, Chr II from 600548-602098,602212-602355, Verified ORF, "Nucleolar component of the pachytene checkpoint, which prevents chromosome segregation when recombination and chromosome synapsis are defective; also represses meiotic interhomolog recombination in the rDNA" |
| 385 | YBR187W | GDT1 SGDID:S000000391, Chr II from 602629-603471, Uncharacterized ORF, "Putative protein of unknown function; expression is reduced in a gcr1 null mutant; GFP-fusion protein localizes to the vacuole; expression pattern and physical interactions suggest a possible role in ribosome biogenesis" |
| 386 | YBR188C | NTC20 SGDID:S000000392, Chr II from 604102-603680, reverse complement, Verified ORF, "Member of a complex, including Prp19p, that binds to the spliceosome; required for pre-mRNA splicing" |
| 387 | YBR189W | RPS9B SGDID:S000000393, Chr II from 604503-604509,604923-605503, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Ap and has similarity to E. coli S4 and rat S9 ribosomal proteins" |
| 388 | YBR191W | RPL21A SGDID:S000000395, Chr II from 606265-606275,606664-607135, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Bp and has similarity to rat L21 ribosomal protein" |
| 389 | YBR192W | RIM2 SGDID:S000000396, Chr II from 607647-608780, Verified ORF, "Mitochondrial pyrimidine nucleotide transporter; imports pyrimidine nucleoside triphosphates and exports pyrimidine nucleoside monophosphates; member of the mitochondrial carrier family" |
| 390 | YBR193C | MED8 SGDID:S000000397, Chr II from 609748-609077, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation" |
| 391 | YBR194W | YBR194W SGDID:S000000398, Chr II from 610033-610404, Uncharacterized ORF, "Protein proposed to be associated with the nuclear pore complex; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and a severe growth defect in minimal glycerol media" |
| 392 | YBR195C | MSI1 SGDID:S000000399, Chr II from 611877-610609, reverse complement, Verified ORF, "Subunit of chromatin assembly factor I (CAF-1), negative regulator of the RAS/cAMP pathway via sequestration of Npr1p kinase; localizes to the nucleus and cytoplasm; homologous to human retinoblastoma binding proteins RbAp48 and RbAp46" |
| 393 | YBR196C | PGI1 SGDID:S000000400, Chr II from 613895-612231, reverse complement, Verified ORF, "Glycolytic enzyme phosphoglucose isomerase, catalyzes the interconversion of glucose-6-phosphate and fructose-6-phosphate; required for cell cycle progression and completion of the gluconeogenic events of sporulation" |
| 394 | YBR196C-A | YBR196C-A SGDID:S000028534, Chr II from 614168-614019, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 395 | YBR196C-B | YBR196C-B SGDID:S000028816, Chr II from 614625-614521, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 396 | YBR197C | YBR197C SGDID:S000000401, Chr II from 615851-615198, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YBR197C is not an essential gene" |
| 397 | YBR198C | TAF5 SGDID:S000000402, Chr II from 618518-616122, reverse complement, Verified ORF, "Subunit (90 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification" |
| 398 | YBR199W | KTR4 SGDID:S000000403, Chr II from 618904-620298, Verified ORF, "Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family" |
| 399 | YBR200W | BEM1 SGDID:S000000404, Chr II from 620867-622522, Verified ORF, "Protein containing SH3-domains, involved in establishing cell polarity and morphogenesis; functions as a scaffold protein for complexes that include Cdc24p, Ste5p, Ste20p, and Rsr1p" |
| 400 | YBR200W-A | YBR200W-A SGDID:S000028535, Chr II from 622978-623142, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 401 | YBR201C-A | YBR201C-A SGDID:S000087085, Chr II from 624692-624489, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 402 | YBR201W | DER1 SGDID:S000000405, Chr II from 623572-624207, Verified ORF, "Endoplasmic reticulum membrane protein, required for ER-associated protein degradation of misfolded or unassembled proteins; N- and C- termini protrude into the cytoplasm, has similarity to Dfm1p" |
| 403 | YBR202W | MCM7 SGDID:S000000406, Chr II from 625767-628304, Verified ORF, "Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase" |
| 404 | YBR203W | COS111 SGDID:S000000407, Chr II from 629163-631937, Verified ORF, "Protein required for resistance to the antifungal drug ciclopirox olamine; not related to the subtelomerically-encoded COS family; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 405 | YBR204C | YBR204C SGDID:S000000408, Chr II from 633376-632249, reverse complement, Uncharacterized ORF, "Serine hydrolase; YBR204C is not an essential gene" |
| 406 | YBR205W | KTR3 SGDID:S000000409, Chr II from 633617-634831, Verified ORF, "Putative alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family" |
| 407 | YBR207W | FTH1 SGDID:S000000411, Chr II from 635141-636538, Verified ORF, "Putative high affinity iron transporter involved in transport of intravacuolar stores of iron; forms complex with Fet5p; expression is regulated by iron; proposed to play indirect role in endocytosis" |
| 408 | YBR208C | DUR1,2 SGDID:S000000412, Chr II from 642205-636698, reverse complement, Verified ORF, "Urea amidolyase, contains both urea carboxylase and allophanate hydrolase activities, degrades urea to CO2 and NH3; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation" |
| 409 | YBR210W | ERV15 SGDID:S000000414, Chr II from 645545-645973, Verified ORF, "Protein involved in export of proteins from the endoplasmic reticulum, has similarity to Erv14p" |
| 410 | YBR211C | AME1 SGDID:S000000415, Chr II from 647127-646153, reverse complement, Verified ORF, "Essential kinetochore protein associated with microtubules and spindle pole bodies; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p); involved in spindle checkpoint maintenance" |
| 411 | YBR212W | NGR1 SGDID:S000000416, Chr II from 647881-649899, Verified ORF, "RNA binding protein that negatively regulates growth rate; interacts with the 3' UTR of the mitochondrial porin (POR1) mRNA and enhances its degradation; overexpression impairs mitochondrial function; expressed in stationary phase" |
| 412 | YBR213W | MET8 SGDID:S000000417, Chr II from 650363-651187, Verified ORF, "Bifunctional dehydrogenase and ferrochelatase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis" |
| 413 | YBR214W | SDS24 SGDID:S000000418, Chr II from 651410-652993, Verified ORF, "One of two S. cerevisiae homologs (Sds23p and Sds24p) of the Schizosaccharomyces pombe Sds23 protein, which genetic studies have implicated in APC/cyclosome regulation; may play an indirect role in fluid-phase endocytosis" |
| 414 | YBR215W | HPC2 SGDID:S000000419, Chr II from 653351-653363,653448-655312, Verified ORF, "Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; mutants display synthetic defects with subunits of FACT, a complex that allows passage of RNA Pol II through nucleosomes" |
| 415 | YBR216C | YBP1 SGDID:S000000420, Chr II from 657595-655571, reverse complement, Verified ORF, "Protein required for oxidation of specific cysteine residues of the transcription factor Yap1p, resulting in the nuclear localization of Yap1p in response to stress" |
| 416 | YBR217W | ATG12 SGDID:S000000421, Chr II from 657827-658387, Verified ORF, "Conserved ubiquitin-like modifier involved in autophagy and the Cvt pathway; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg12p-Atg5p also forms a complex with Atg16p that is required for autophagosome formation" |
| 417 | YBR218C | PYC2 SGDID:S000000422, Chr II from 662244-658702, reverse complement, Verified ORF, "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc1p but differentially regulated; mutations in the human homolog are associated with lactic acidosis" |
| 418 | YBR219C | YBR219C SGDID:S000000423, Chr II from 663298-662998,662576-662494, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YBR219C is not an essential gene" |
| 419 | YBR220C | YBR220C SGDID:S000000424, Chr II from 664672-662990, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YBR220C is not an essential gene" |
| 420 | YBR221C | PDB1 SGDID:S000000425, Chr II from 666248-665148, reverse complement, Verified ORF, "E1 beta subunit of the pyruvate dehydrogenase (PDH) complex, which is an evolutionarily-conserved multi-protein complex found in mitochondria" |
| 421 | YBR221W-A | YBR221W-A SGDID:S000028817, Chr II from 666533-666637, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 422 | YBR222C | PCS60 SGDID:S000000426, Chr II from 668346-666715, reverse complement, Verified ORF, "Peroxisomal AMP-binding protein, localizes to both the peroxisomal peripheral membrane and matrix, expression is highly inducible by oleic acid, similar to E. coli long chain acyl-CoA synthetase" |
| 423 | YBR223C | TDP1 SGDID:S000000427, Chr II from 670292-668658, reverse complement, Verified ORF, "Tyrosyl-DNA Phosphodiesterase I, hydrolyzes 3'-phosphotyrosyl bonds to generate 3'-phosphate DNA and tyrosine, involved in the repair of DNA lesions created by topoisomerase I" |
| 424 | YBR225W | YBR225W SGDID:S000000429, Chr II from 670622-673324, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene identified in a screen for mutants affected in mannosylphophorylation of cell wall components" |
| 425 | YBR227C | MCX1 SGDID:S000000431, Chr II from 675129-673567, reverse complement, Verified ORF, "Mitochondrial ATP-binding protein, possibly a mitochondrial chaperone with non-proteolytic function; similar to bacterial ClpX proteins" |
| 426 | YBR228W | SLX1 SGDID:S000000432, Chr II from 675308-676222, Verified ORF, "Subunit of a complex, with Slx4p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p" |
| 427 | YBR229C | ROT2 SGDID:S000000433, Chr II from 679216-676352, reverse complement, Verified ORF, "Glucosidase II catalytic subunit required for normal cell wall synthesis; mutations in rot2 suppress tor2 mutations, and are synthetically lethal with rot1 mutations" |
| 428 | YBR230C | OM14 SGDID:S000000434, Chr II from 680045-680035,679937-679544, reverse complement, Verified ORF, "Integral mitochondrial outer membrane protein; abundance is decreased in cells grown in glucose relative to other carbon sources; appears to contain 3 alpha-helical transmembrane segments; ORF encodes a 97-basepair intron" |
| 429 | YBR230W-A | YBR230W-A SGDID:S000029722, Chr II from 680357-680557, Uncharacterized ORF, "Putative protein of unknown function" |
| 430 | YBR231C | SWC5 SGDID:S000000435, Chr II from 683085-682174, reverse complement, Verified ORF, "Protein of unknown function, component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A" |
| 431 | YBR233W | PBP2 SGDID:S000000437, Chr II from 683423-684664, Verified ORF, "RNA binding protein with similarity to mammalian heterogeneous nuclear RNP K protein, involved in the regulation of telomere position effect and telomere length" |
| 432 | YBR233W-A | DAD3 SGDID:S000007595, Chr II from 684972-685256, Verified ORF, "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" |
| 433 | YBR234C | ARC40 SGDID:S000000438, Chr II from 686587-685433, reverse complement, Verified ORF, "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches" |
| 434 | YBR235W | YBR235W SGDID:S000000439, Chr II from 686896-690258, Uncharacterized ORF, "Putative ion transporter, similar to mammalian electroneutral Na(+)-(K+)-C1- cotransporter family; YBR235W is not an essential gene" |
| 435 | YBR236C | ABD1 SGDID:S000000440, Chr II from 691688-690378, reverse complement, Verified ORF, "Methyltransferase, catalyzes the transfer of a methyl group from S-adenosylmethionine to the GpppN terminus of capped mRNA" |
| 436 | YBR237W | PRP5 SGDID:S000000441, Chr II from 691964-694513, Verified ORF, "RNA helicase in the DEAD-box family, necessary for prespliceosome formation, bridges U1 and U2 snRNPs and enables stable U2 snRNP association with intron RNA" |
| 437 | YBR238C | YBR238C SGDID:S000000442, Chr II from 697297-695102, reverse complement, Verified ORF, "Mitochondrial membrane protein with similarity to Rmd9p; not required for respiratory growth but causes a synthetic respiratory defect in combination with rmd9 mutations; transcriptionally up-regulated by TOR; deletion increases life span" |
| 438 | YBR239C | YBR239C SGDID:S000000443, Chr II from 699938-698349, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; plays a role in restricting Ty1 transposition" |
| 439 | YBR240C | THI2 SGDID:S000000444, Chr II from 701837-700485, reverse complement, Verified ORF, "Zinc finger protein of the Zn(II)2Cys6 type, probable transcriptional activator of thiamine biosynthetic genes" |
| 440 | YBR241C | YBR241C SGDID:S000000445, Chr II from 704050-702584, reverse complement, Uncharacterized ORF, "Putative transporter, member of the sugar porter family; green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane; YBR241C is not an essential gene" |
| 441 | YBR242W | YBR242W SGDID:S000000446, Chr II from 704665-705381, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YBR242W is not an essential gene" |
| 442 | YBR243C | ALG7 SGDID:S000000447, Chr II from 706788-705442, reverse complement, Verified ORF, "UDP-N-acetyl-glucosamine-1-P transferase, transfers Glc-Nac-P from UDP-GlcNac to Dol-P in the ER in the first step of the dolichol pathway of protein asparagine-linked glycosylation; inhibited by tunicamycin" |
| 443 | YBR244W | GPX2 SGDID:S000000448, Chr II from 707523-708011, Verified ORF, "Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress" |
| 444 | YBR245C | ISW1 SGDID:S000000449, Chr II from 711534-708145, reverse complement, Verified ORF, "Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase that forms a complex with Ioc2p and Ioc4p to regulate transcription elongation, and a complex with Ioc3p to repress transcription initiation" |
| 445 | YBR246W | YBR246W SGDID:S000000450, Chr II from 711586-712749, Uncharacterized ORF, "Putative protein of unknown function; deletion results in a weak carboxypeptidase Y missorting/secretion phenotype; YBR246W is not an essential gene" |
| 446 | YBR247C | ENP1 SGDID:S000000451, Chr II from 714450-712999, reverse complement, Verified ORF, "Protein associated with U3 and U14 snoRNAs, required for pre-rRNA processing and 40S ribosomal subunit synthesis; localized in the nucleus and concentrated in the nucleolus" |
| 447 | YBR248C | HIS7 SGDID:S000000452, Chr II from 716460-714802, reverse complement, Verified ORF, "Imidazole glycerol phosphate synthase (glutamine amidotransferase:cyclase), catalyzes the fifth and sixth steps of histidine biosynthesis and also produces 5-aminoimidazole-4-carboxamide ribotide (AICAR), a purine precursor" |
| 448 | YBR249C | ARO4 SGDID:S000000453, Chr II from 717989-716877, reverse complement, Verified ORF, "3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by tyrosine or high concentrations of phenylalanine or tryptophan" |
| 449 | YBR250W | SPO23 SGDID:S000000454, Chr II from 719028-720599, Verified ORF, "Protein of unknown function; associates with meiosis-specific protein Spo1p" |
| 450 | YBR251W | MRPS5 SGDID:S000000455, Chr II from 721385-722308, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 451 | YBR252W | DUT1 SGDID:S000000456, Chr II from 722606-723049, Verified ORF, "dUTPase, catalyzes hydrolysis of dUTP to dUMP and PPi, thereby preventing incorporation of uracil into DNA during replication; critical for the maintenance of genetic stability" |
| 452 | YBR253W | SRB6 SGDID:S000000457, Chr II from 723265-723630, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation" |
| 453 | YBR254C | TRS20 SGDID:S000000458, Chr II from 724258-723731, reverse complement, Verified ORF, "One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; mutations in the human homolog cause the spondyloepiphyseal dysplasia tarda (SEDL) disorder" |
| 454 | YBR255C-A | YBR255C-A SGDID:S000007649, Chr II from 727069-727007,726912-726613, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by sequence comparison with hemiascomycetous yeast species" |
| 455 | YBR255W | YBR255W SGDID:S000000459, Chr II from 724451-726535, Uncharacterized ORF, "Protein of unknown function, required for normal growth rate at 15 degrees C; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YBR255W is synthetically sick with cdc13-1" |
| 456 | YBR256C | RIB5 SGDID:S000000460, Chr II from 728097-727381, reverse complement, Verified ORF, "Riboflavin synthase; catalyzes the last step of the riboflavin biosynthesis pathway" |
| 457 | YBR257W | POP4 SGDID:S000000461, Chr II from 728880-729719, Verified ORF, "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in Rnase P" |
| 458 | YBR258C | SHG1 SGDID:S000000462, Chr II from 730157-729729, reverse complement, Verified ORF, "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres" |
| 459 | YBR259W | YBR259W SGDID:S000000463, Chr II from 730382-732448, Uncharacterized ORF, "Putative protein of unknown function; YBR259W is not an essential gene" |
| 460 | YBR260C | RGD1 SGDID:S000000464, Chr II from 734634-732634, reverse complement, Verified ORF, "GTPase-activating protein (RhoGAP) for Rho3p and Rho4p, possibly involved in control of actin cytoskeleton organization" |
| 461 | YBR261C | YBR261C SGDID:S000000465, Chr II from 735525-734827, reverse complement, Uncharacterized ORF, "Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YBR261C is not an essential gene" |
| 462 | YBR262C | YBR262C SGDID:S000000466, Chr II from 736035-735715, reverse complement, Uncharacterized ORF, "Protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays decreased frequency of mitochondrial genome loss and reduced growth rate in minimal glycerol media" |
| 463 | YBR263W | SHM1 SGDID:S000000467, Chr II from 736259-737731, Verified ORF, "Mitochondrial serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrofolate; involved in generating precursors for purine, pyrimidine, amino acid, and lipid biosynthesis; reverse reaction generates serine" |
| 464 | YBR264C | YPT10 SGDID:S000000468, Chr II from 738364-737765, reverse complement, Verified ORF, "GTP binding protein that contains the PEST signal sequence specific for proteolytic enzymes; may be involved in vesicular transport; overexpression leads to accumulation of Golgi-like cisternae with budding vesicles" |
| 465 | YBR265W | TSC10 SGDID:S000000469, Chr II from 738577-739539, Verified ORF, "3-ketosphinganine reductase, catalyzes the second step in phytosphingosine synthesis, essential for growth in the absence of exogenous dihydrosphingosine or phytosphingosine, member of short chain dehydrogenase/reductase protein family" |
| 466 | YBR267W | REI1 SGDID:S000000471, Chr II from 739836-741017, Verified ORF, "Cytoplasmic pre-60S factor; required for the correct recycling of shuttling factors Alb1, Arx1 and Tif6 at the end of the ribosomal large subunit biogenesis; involved in bud growth in the mitotic signaling network" |
| 467 | YBR268W | MRPL37 SGDID:S000000472, Chr II from 741294-741611, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 468 | YBR269C | YBR269C SGDID:S000000473, Chr II from 742571-742155, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 469 | YBR270C | YBR270C SGDID:S000000474, Chr II from 744393-742756, reverse complement, Uncharacterized ORF, "Hypothetical protein" |
| 470 | YBR271W | YBR271W SGDID:S000000475, Chr II from 744847-746106, Uncharacterized ORF, "Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YBR271W is not as essential gene" |
| 471 | YBR272C | HSM3 SGDID:S000000476, Chr II from 747798-746356, reverse complement, Verified ORF, "Protein of unknown function, involved in DNA mismatch repair during slow growth; has weak similarity to Msh1p" |
| 472 | YBR273C | UBX7 SGDID:S000000477, Chr II from 749366-748056, reverse complement, Verified ORF, "UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p" |
| 473 | YBR274W | CHK1 SGDID:S000000478, Chr II from 749589-751172, Verified ORF, "Serine/threonine kinase and DNA damage checkpoint effector, mediates cell cycle arrest via phosphorylation of Pds1p; phosphorylated by checkpoint signal transducer Mec1p; homolog of S. pombe and mammalian Chk1 checkpoint kinase" |
| 474 | YBR275C | RIF1 SGDID:S000000479, Chr II from 757101-751351, reverse complement, Verified ORF, "Protein that binds to the Rap1p C-terminus and acts synergistically with Rif2p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation" |
| 475 | YBR276C | PPS1 SGDID:S000000480, Chr II from 760039-757616, reverse complement, Verified ORF, "Protein phosphatase with specificity for serine, threonine, and tyrosine residues; has a role in the DNA synthesis phase of the cell cycle" |
| 476 | YBR278W | DPB3 SGDID:S000000482, Chr II from 760290-760895, Verified ORF, "Third-largest subunit of DNA polymerase II (DNA polymerase epsilon), required to maintain fidelity of chromosomal replication and also for inheritance of telomeric silencing; mRNA abundance peaks at the G1/S boundary of the cell cycle" |
| 477 | YBR279W | PAF1 SGDID:S000000483, Chr II from 761253-762590, Verified ORF, "RNAP II-associated protein; defines large complex biochemically and functionally distinct from the Srb-Mediator form of Pol II holoenzyme; required for full expression of a subset of cell cycle-regulated genes; homolog of human PD2/hPAF1" |
| 478 | YBR280C | SAF1 SGDID:S000000484, Chr II from 764693-762780, reverse complement, Verified ORF, "F-Box protein involved in proteasome-dependent degradation of Aah1p during entry of cells into quiescence; interacts with Skp1" |
| 479 | YBR281C | DUG2 SGDID:S000000485, Chr II from 767602-764966, reverse complement, Verified ORF, "Probable di- and tri-peptidase; forms a complex with Dug1p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)" |
| 480 | YBR282W | MRPL27 SGDID:S000000486, Chr II from 768236-768676, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 481 | YBR283C | SSH1 SGDID:S000000487, Chr II from 770411-768939, reverse complement, Verified ORF, "Subunit of the Ssh1 translocon complex; Sec61p homolog involved in co-translational pathway of protein translocation; not essential" |
| 482 | YBR284W | YBR284W SGDID:S000000488, Chr II from 771235-773628, Uncharacterized ORF, "Putative protein of unknown function; YBR284W is not an essential gene; null mutant exhibits decreased resistance to rapamycin and wortmannin" |
| 483 | YBR285W | YBR285W SGDID:S000000489, Chr II from 773918-774352, Uncharacterized ORF, "Putative protein of unknown function; YBR285W is not an essential gene and deletion of YBR285W leads to poor growth on glucose-minimal medium at 15C" |
| 484 | YBR286W | APE3 SGDID:S000000490, Chr II from 774696-776309, Verified ORF, "Vacuolar aminopeptidase Y, processed to mature form by Prb1p" |
| 485 | YBR287W | YBR287W SGDID:S000000491, Chr II from 776567-777850, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER; YBR287W is not an essential gene" |
| 486 | YBR288C | APM3 SGDID:S000000492, Chr II from 779459-778008, reverse complement, Verified ORF, "Mu3-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway" |
| 487 | YBR289W | SNF5 SGDID:S000000493, Chr II from 779663-782380, Verified ORF, "Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf6p" |
| 488 | YBR290W | BSD2 SGDID:S000000494, Chr II from 782587-783552, Verified ORF, "Heavy metal ion homeostasis protein, facilitates trafficking of Smf1p and Smf2p metal transporters to the vacuole where they are degraded, controls metal ion transport, prevents metal hyperaccumulation, functions in copper detoxification" |
| 489 | YBR291C | CTP1 SGDID:S000000495, Chr II from 784568-783669, reverse complement, Verified ORF, "Mitochondrial inner membrane citrate transporter, member of the mitochondrial carrier family" |
| 490 | YBR293W | VBA2 SGDID:S000000497, Chr II from 787001-788425, Verified ORF, "Permease of basic amino acids in the vacuolar membrane" |
| 491 | YBR294W | SUL1 SGDID:S000000498, Chr II from 789230-791809, Verified ORF, "High affinity sulfate permease; sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p, which control the concentration of endogenous activated sulfate intermediates" |
| 492 | YBR295W | PCA1 SGDID:S000000499, Chr II from 792843-796493, Verified ORF, "Cadmium transporting P-type ATPase; may also have a role in copper and iron homeostasis; S288C and most other lab strains contain a G970R mutation which eliminates normal cadmium transport function" |
| 493 | YBR296C | PHO89 SGDID:S000000500, Chr II from 798516-796792, reverse complement, Verified ORF, "Na+/Pi cotransporter, active in early growth phase; similar to phosphate transporters of Neurospora crassa; transcription regulated by inorganic phosphate concentrations and Pho4p" |
| 494 | YBR296C-A | YBR296C-A SGDID:S000028605, Chr II from 800236-800117, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 495 | YBR297W | MAL33 SGDID:S000000501, Chr II from 800517-801923, Verified ORF, "MAL-activator protein, part of complex locus MAL3; nonfunctional in genomic reference strain S288C" |
| 496 | YBR298C | MAL31 SGDID:S000000502, Chr II from 804469-802625, reverse complement, Verified ORF, "Maltose permease, high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL3 complex locus; member of the 12 transmembrane domain superfamily of sugar transporters; functional in genomic reference strain S288C" |
| 497 | YBR298C-A | YBR298C-A SGDID:S000028606, Chr II from 805250-805029, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 498 | YBR299W | MAL32 SGDID:S000000503, Chr II from 805345-807099, Verified ORF, "Maltase (alpha-D-glucosidase), inducible protein involved in maltose catabolism; encoded in the MAL3 complex locus; functional in genomic reference strain S288C" |
| 499 | YBR301W | DAN3 SGDID:S000000505, Chr II from 809051-809413, Verified ORF, "Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth" |
| 500 | YBR302C | COS2 SGDID:S000000506, Chr II from 811473-810334, reverse complement, Verified ORF, "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" |
| 501 | YCL001W | RER1 SGDID:S000000507, Chr III from 111914-112480, Verified ORF, "Protein involved in retention of membrane proteins, including Sec12p, in the ER; localized to Golgi; functions as a retrieval receptor in returning membrane proteins to the ER" |
| 502 | YCL001W-A | YCL001W-A SGDID:S000007221, Chr III from 113078-113539, Uncharacterized ORF, "Putative protein of unknown function; YCL001W-A is not an essential gene" |
| 503 | YCL001W-B | YCL001W-B SGDID:S000007596, Chr III from 113768-114022, Uncharacterized ORF, "Putative protein of unknown function; identified by homology" |
| 504 | YCL002C | YCL002C SGDID:S000000508, Chr III from 111674-111633,111556-110843, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YCL002C is not an essential gene" |
| 505 | YCL004W | PGS1 SGDID:S000000510, Chr III from 109105-110670, Verified ORF, "Phosphatidylglycerolphosphate synthase, catalyzes the synthesis of phosphatidylglycerolphosphate from CDP-diacylglycerol and sn-glycerol 3-phosphate in the first committed and rate-limiting step of cardiolipin biosynthesis" |
| 506 | YCL005W | LDB16 SGDID:S000000511, Chr III from 108021-108791, Verified ORF, "Protein of unknown function; null mutants have decreased net negative cell surface charge; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; native protein is detected in purified mitochondria" |
| 507 | YCL005W-A | VMA9 SGDID:S000028508, Chr III from 107023-107033,107111-107191,107288-107417, Verified ORF, "Vacuolar H+ ATPase subunit e of the V-ATPase V0 subcomplex; essential for vacuolar acidification; interacts with the V-ATPase assembly factor Vma21p in the ER; involved in V0 biogenesis" |
| 508 | YCL008C | STP22 SGDID:S000000514, Chr III from 106853-105696, reverse complement, Verified ORF, "Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; homologous to the mouse and human Tsg101 tumor susceptibility gene; mutants exhibit a Class E Vps phenotype" |
| 509 | YCL009C | ILV6 SGDID:S000000515, Chr III from 105548-104619, reverse complement, Verified ORF, "Regulatory subunit of acetolactate synthase, which catalyzes the first step of branched-chain amino acid biosynthesis; enhances activity of the Ilv2p catalytic subunit, localizes to mitochondria" |
| 510 | YCL010C | SGF29 SGDID:S000000516, Chr III from 104350-103571, reverse complement, Verified ORF, "SaGa associated Factor 29kDa; Probable 29kKDa Subunit of SAGA histone acetyltransferase complex" |
| 511 | YCL011C | GBP2 SGDID:S000000517, Chr III from 103358-102075, reverse complement, Verified ORF, "Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Hrb1p and Npl3p; also binds single-stranded telomeric repeat sequence in vitro" |
| 512 | YCL012C | YCL012C SGDID:S000029705, Chr III from 101788-101701,101633-101317, reverse complement, Verified ORF, "Putative protein of unknown function; orthologs are present in S. bayanus, S. paradoxus and Ashbya gossypii; YCL012C is not an essential gene" |
| 513 | YCL014W | BUD3 SGDID:S000000520, Chr III from 96281-101191, Verified ORF, "Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding" |
| 514 | YCL016C | DCC1 SGDID:S000000521, Chr III from 95763-94621, reverse complement, Verified ORF, "Subunit of a complex with Ctf8p and Ctf18p that shares some components with Replication Factor C, required for sister chromatid cohesion and telomere length maintenance" |
| 515 | YCL017C | NFS1 SGDID:S000000522, Chr III from 94270-92777, reverse complement, Verified ORF, "Cysteine desulfurase involved in iron-sulfur cluster (Fe/S) biogenesis; required for the post-transcriptional thio-modification of mitochondrial and cytoplasmic tRNAs; essential protein located predominantly in mitochondria" |
| 516 | YCL018W | LEU2 SGDID:S000000523, Chr III from 91324-92418, Verified ORF, "Beta-isopropylmalate dehydrogenase (IMDH), catalyzes the third step in the leucine biosynthesis pathway" |
| 517 | YCL019W | YCL019W SGDID:S000000524, Chr III from 85102-86391,86393-90415, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 518 | YCL020W | YCL020W SGDID:S000000525, Chr III from 85102-86418, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 519 | YCL021W-A | YCL021W-A SGDID:S000007549, Chr III from 83620-83997, Uncharacterized ORF, "Putative protein of unknown function" |
| 520 | YCL024W | KCC4 SGDID:S000000529, Chr III from 79162-82275, Verified ORF, "Protein kinase of the bud neck involved in the septin checkpoint, associates with septin proteins, negatively regulates Swe1p by phosphorylation, shows structural homology to bud neck kinases Gin4p and Hsl1p" |
| 521 | YCL025C | AGP1 SGDID:S000000530, Chr III from 77919-76018, reverse complement, Verified ORF, "Low-affinity amino acid permease with broad substrate range, involved in uptake of asparagine, glutamine, and other amino acids; expression is regulated by the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p)" |
| 522 | YCL026C-A | FRM2 SGDID:S000000589, Chr III from 75285-74704, reverse complement, Verified ORF, "Protein of unknown function, involved in the integration of lipid signaling pathways with cellular homeostasis; similar to bacterial nitroreductases" |
| 523 | YCL026C-B | HBN1 SGDID:S000007548, Chr III from 73986-73405, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; similar to bacterial nitroreductases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
| 524 | YCL027W | FUS1 SGDID:S000000532, Chr III from 71803-73341, Verified ORF, "Membrane protein localized to the shmoo tip, required for cell fusion; expression regulated by mating pheromone; proposed to coordinate signaling, fusion, and polarization events required for fusion; potential Cdc28p substrate" |
| 525 | YCL028W | RNQ1 SGDID:S000000533, Chr III from 70150-71367, Verified ORF, "[PIN(+)] prion, an infectious protein conformation that is generally an ordered protein aggregate" |
| 526 | YCL029C | BIK1 SGDID:S000000534, Chr III from 69921-68599, reverse complement, Verified ORF, "Microtubule-associated protein, component of the interface between microtubules and kinetochore, involved in sister chromatid separation; essential in polyploid cells but not in haploid or diploid cells; ortholog of mammalian CLIP-170" |
| 527 | YCL030C | HIS4 SGDID:S000000535, Chr III from 68333-65934, reverse complement, Verified ORF, "Multifunctional enzyme containing phosphoribosyl-ATP pyrophosphatase, phosphoribosyl-AMP cyclohydrolase, and histidinol dehydrogenase activities; catalyzes the second, third, ninth and tenth steps in histidine biosynthesis" |
| 528 | YCL031C | RRP7 SGDID:S000000536, Chr III from 65568-64675, reverse complement, Verified ORF, "Essential protein involved in rRNA processing and ribosome biogenesis" |
| 529 | YCL032W | STE50 SGDID:S000000537, Chr III from 63441-64481, Verified ORF, "Protein involved in mating response, invasive/filamentous growth, and osmotolerance, acts as an adaptor that links G protein-associated Cdc42p-Ste20p complex to the effector Ste11p to modulate signal transduction" |
| 530 | YCL033C | YCL033C SGDID:S000000538, Chr III from 63282-62776, reverse complement, Uncharacterized ORF, "Putative protein-methionine-R-oxide reductase; involved in response to oxidative stress; similar to mouse Sepx1p and fly SelRp; YCL033C is not an essential gene" |
| 531 | YCL034W | LSB5 SGDID:S000000539, Chr III from 61658-62722, Verified ORF, "Protein of unknown function; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization" |
| 532 | YCL035C | GRX1 SGDID:S000000540, Chr III from 61173-60841, reverse complement, Verified ORF, "Hydroperoxide and superoxide-radical responsive heat-stable glutathione-dependent disulfide oxidoreductase with active site cysteine pair; protects cells from oxidative damage" |
| 533 | YCL036W | GFD2 SGDID:S000000541, Chr III from 59026-60726, Verified ORF, "Protein of unknown function, identified as a high-copy suppressor of a dbp5 mutation" |
| 534 | YCL037C | SRO9 SGDID:S000000542, Chr III from 58678-57374, reverse complement, Verified ORF, "Cytoplasmic RNA-binding protein that associates with translating ribosomes; involved in heme regulation of Hap1p as a component of the HMC complex, also involved in the organization of actin filaments; contains a La motif" |
| 535 | YCL038C | ATG22 SGDID:S000000543, Chr III from 56527-54941, reverse complement, Verified ORF, "Vacuolar integral membrane protein required for efflux of amino acids during autophagic body breakdown in the vacuole; null mutation causes a gradual loss of viability during starvation" |
| 536 | YCL039W | GID7 SGDID:S000000544, Chr III from 52645-54882, Verified ORF, "Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains six WD40 repeats; computational analysis suggests that Gid7p and Moh1p have similar functions" |
| 537 | YCL040W | GLK1 SGDID:S000000545, Chr III from 50838-52340, Verified ORF, "Glucokinase, catalyzes the phosphorylation of glucose at C6 in the first irreversible step of glucose metabolism; one of three glucose phosphorylating enzymes; expression regulated by non-fermentable carbon sources" |
| 538 | YCL042W | YCL042W SGDID:S000000547, Chr III from 50584-50943, Uncharacterized ORF, "Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm" |
| 539 | YCL043C | PDI1 SGDID:S000000548, Chr III from 50221-48653, reverse complement, Verified ORF, "Protein disulfide isomerase, multifunctional protein resident in the endoplasmic reticulum lumen, essential for the formation of disulfide bonds in secretory and cell-surface proteins, unscrambles non-native disulfide bonds" |
| 540 | YCL044C | MGR1 SGDID:S000000549, Chr III from 48364-47111, reverse complement, Verified ORF, "Subunit, with Yme1p, of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; required for growth of cells lacking the mitochondrial genome" |
| 541 | YCL045C | YCL045C SGDID:S000000550, Chr III from 46905-44623, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the ER; interacts with Gal80p; YCL045C is not an essential gene" |
| 542 | YCL047C | YCL047C SGDID:S000000552, Chr III from 44437-43661, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 543 | YCL048W | SPS22 SGDID:S000000553, Chr III from 42165-43556, Verified ORF, "Protein of unknown function, redundant with Sps2p for the organization of the beta-glucan layer of the spore wall" |
| 544 | YCL048W-A | YCL048W-A SGDID:S000087203, Chr III from 41488-41727, Uncharacterized ORF, "Putative protein of unknown function" |
| 545 | YCL049C | YCL049C SGDID:S000000554, Chr III from 40724-39786, reverse complement, Uncharacterized ORF, "Protein of unknown function; localizes to membrane fraction; YCL049C is not an essential gene;" |
| 546 | YCL050C | APA1 SGDID:S000000555, Chr III from 38801-37836, reverse complement, Verified ORF, "Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase I (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa2p" |
| 547 | YCL051W | LRE1 SGDID:S000000556, Chr III from 35865-37616, Verified ORF, "Protein involved in control of cell wall structure and stress response; inhibits Cbk1p protein kinase activity; overproduction confers resistance to cell-wall degrading enzymes" |
| 548 | YCL052C | PBN1 SGDID:S000000557, Chr III from 35393-34143, reverse complement, Verified ORF, "Essential component of glycosylphosphatidylinositol-mannosyltransferase I, required for the autocatalytic post-translational processing of the protease B precursor Prb1p, localizes to ER in lumenal orientation; homolog of mammalian PIG-X" |
| 549 | YCL054W | SPB1 SGDID:S000000559, Chr III from 31449-33974, Verified ORF, "AdoMet-dependent methyltransferase involved in rRNA processing and 60S ribosomal subunit maturation; methylates G2922 in the tRNA docking site of the large subunit rRNA and in the absence of snR52, U2921; suppressor of PAB1 mutants" |
| 550 | YCL055W | KAR4 SGDID:S000000560, Chr III from 27929-28936, Verified ORF, "Transcription factor required for gene regulation in repsonse to pheromones; also required during meiosis; exists in two forms, a slower-migrating form more abundant during vegetative growth and a faster-migrating form induced by pheromone" |
| 551 | YCL056C | YCL056C SGDID:S000000561, Chr III from 27359-26925, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 552 | YCL057C-A | YCL057C-A SGDID:S000007547, Chr III from 24325-24032, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 553 | YCL057W | PRD1 SGDID:S000000562, Chr III from 24768-26906, Verified ORF, "Zinc metalloendopeptidase, found in the cytoplasm and intermembrane space of mitochondria; with Cym1p, involved in degradation of mitochondrial proteins and of presequence peptides cleaved from imported proteins" |
| 554 | YCL058W-A | YCL058W-A SGDID:S000028518, Chr III from 23584-23925, Uncharacterized ORF, "Protein of unknown function; identified by homology to Ashbya gossypii" |
| 555 | YCL059C | KRR1 SGDID:S000000564, Chr III from 23379-22429, reverse complement, Verified ORF, "Essential nucleolar protein required for the synthesis of 18S rRNA and for the assembly of 40S ribosomal subunit" |
| 556 | YCL061C | MRC1 SGDID:S000000566, Chr III from 22106-18816, reverse complement, Verified ORF, "S-phase checkpoint protein found at replication forks, required for DNA replication; also required for Rad53p activation during DNA replication stress, where it forms a replication-pausing complex with Tof1p and is phosphorylated by Mec1p" |
| 557 | YCL063W | VAC17 SGDID:S000000568, Chr III from 17290-18561, Verified ORF, "Protein involved in vacuole inheritance; acts as a vacuole-specific receptor for myosin Myo2p" |
| 558 | YCL064C | CHA1 SGDID:S000000569, Chr III from 16880-15798, reverse complement, Verified ORF, "Catabolic L-serine (L-threonine) deaminase, catalyzes the degradation of both L-serine and L-threonine; required to use serine or threonine as the sole nitrogen source, transcriptionally induced by serine and threonine" |
| 559 | YCL066W | HMLALPHA1 SGDID:S000000571, Chr III from 13282-13809, Verified silenced_gene ORF, "Silenced copy of ALPHA1 at HML, encoding a transcriptional coactivator involved in the regulation of mating-type alpha-specific gene expression" |
| 560 | YCL067C | HMLALPHA2 SGDID:S000000572, Chr III from 13018-12386, reverse complement, Verified silenced_gene ORF, "Silenced copy of ALPHA2 at HML; homeobox-domain protein that associates with Mcm1p in haploid cells to repress a-specific gene expression and interacts with a1p in diploid cells to repress haploid-specific gene expression" |
| 561 | YCL068C | YCL068C SGDID:S000000573, Chr III from 12285-11503, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 562 | YCL069W | VBA3 SGDID:S000000574, Chr III from 9706-11082, Verified ORF, "Permease of basic amino acids in the vacuolar membrane" |
| 563 | YCL073C | YCL073C SGDID:S000000575, Chr III from 8326-6479, reverse complement, Uncharacterized ORF, "Protein of unconfirmed function; displays a topology characteristic of the Major Facilitators Superfamily of membrane proteins; coding sequence 98% identical to that of YKR106W" |
| 564 | YCR002C | CDC10 SGDID:S000000595, Chr III from 118346-117378, reverse complement, Verified ORF, "Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM" |
| 565 | YCR003W | MRPL32 SGDID:S000000596, Chr III from 118618-119169, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 566 | YCR004C | YCP4 SGDID:S000000597, Chr III from 120316-119573, reverse complement, Verified ORF, "Protein of unknown function, has sequence and structural similarity to flavodoxins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 567 | YCR005C | CIT2 SGDID:S000000598, Chr III from 122326-120944, reverse complement, Verified ORF, "Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate, peroxisomal isozyme involved in glyoxylate cycle; expression is controlled by Rtg1p and Rtg2p transcription factors" |
| 568 | YCR007C | YCR007C SGDID:S000000600, Chr III from 126728-126009, reverse complement, Uncharacterized ORF, "Putative integral membrane protein, member of DUP240 gene family; YCR007C is not an essential gene" |
| 569 | YCR008W | SAT4 SGDID:S000000601, Chr III from 128468-130279, Verified ORF, "Ser/Thr protein kinase involved in salt tolerance; funtions in regulation of Trk1p-Trk2p potassium transporter; partially redundant with Hal5p; has similarity to Npr1p" |
| 570 | YCR009C | RVS161 SGDID:S000000602, Chr III from 131540-130743, reverse complement, Verified ORF, "Amphiphysin-like lipid raft protein; subunit of a complex (Rvs161p-Rvs167p) that regulates polarization of the actin cytoskeleton, endocytosis, cell polarity, cell fusion and viability following starvation or osmotic stress" |
| 571 | YCR010C | ADY2 SGDID:S000000603, Chr III from 133122-132271, reverse complement, Verified ORF, "Acetate transporter required for normal sporulation; phosphorylated in mitochondria" |
| 572 | YCR011C | ADP1 SGDID:S000000604, Chr III from 136871-133722, reverse complement, Verified ORF, "Putative ATP-dependent permease of the ABC transporter family of proteins" |
| 573 | YCR012W | PGK1 SGDID:S000000605, Chr III from 137744-138994, Verified ORF, "3-phosphoglycerate kinase, catalyzes transfer of high-energy phosphoryl groups from the acyl phosphate of 1,3-bisphosphoglycerate to ADP to produce ATP; key enzyme in glycolysis and gluconeogenesis" |
| 574 | YCR014C | POL4 SGDID:S000000607, Chr III from 140931-139183, reverse complement, Verified ORF, "DNA polymerase IV, undergoes pair-wise interactions with Dnl4p-Lif1p and Rad27p to mediate repair of DNA double-strand breaks by non-homologous end joining (NHEJ); homologous to mammalian DNA polymerase beta" |
| 575 | YCR015C | YCR015C SGDID:S000000608, Chr III from 142168-141215, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YCR015C is not an essential gene" |
| 576 | YCR016W | YCR016W SGDID:S000000609, Chr III from 143632-144504, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus and nucleus; YCR016W is not an essential gene" |
| 577 | YCR017C | CWH43 SGDID:S000000610, Chr III from 147632-144771, reverse complement, Verified ORF, "Putative sensor/transporter protein involved in cell wall biogenesis; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion" |
| 578 | YCR018C | SRD1 SGDID:S000000611, Chr III from 148901-148236, reverse complement, Verified ORF, "Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation" |
| 579 | YCR019W | MAK32 SGDID:S000000612, Chr III from 152835-153926, Verified ORF, "Protein necessary for structural stability of L-A double-stranded RNA-containing particles" |
| 580 | YCR020C | PET18 SGDID:S000000613, Chr III from 154657-154010, reverse complement, Verified ORF, "Protein required for respiratory growth and stability of the mitochondrial genome" |
| 581 | YCR020C-A | MAK31 SGDID:S000000614, Chr III from 155094-154828, reverse complement, Verified ORF, "Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus; member of the Sm protein family" |
| 582 | YCR020W-B | HTL1 SGDID:S000006439, Chr III from 155318-155554, Verified ORF, "Component of the RSC chromatin remodeling complex; RSC functions in transcriptional regulation and elongation, chromosome stability, and establishing sister chromatid cohesion; involved in telomere maintenance" |
| 583 | YCR021C | HSP30 SGDID:S000000615, Chr III from 157103-156105, reverse complement, Verified ORF, "Hydrophobic plasma membrane localized, stress-responsive protein that negatively regulates the H(+)-ATPase Pma1p; induced by heat shock, ethanol treatment, weak organic acid, glucose limitation, and entry into stationary phase" |
| 584 | YCR023C | YCR023C SGDID:S000000617, Chr III from 160369-158534, reverse complement, Verified ORF, "Vacuolar membrane protein of unknown function; member of the multidrug resistance family; YCR023C is not an essential gene" |
| 585 | YCR024C | SLM5 SGDID:S000000618, Chr III from 162218-160740, reverse complement, Verified ORF, "Mitochondrial asparaginyl-tRNA synthetase" |
| 586 | YCR024C-A | PMP1 SGDID:S000000619, Chr III from 163063-162941, reverse complement, Verified ORF, "Small single-membrane span proteolipid that functions as a regulatory subunit of the plasma membrane H(+)-ATPase Pma1p, forms unique helix and positively charged cytoplasmic domain that is able to specifically segregate phosphatidylserines" |
| 587 | YCR024C-B | YCR024C-B SGDID:S000028818, Chr III from 162861-162595, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 588 | YCR026C | NPP1 SGDID:S000000621, Chr III from 166335-164107, reverse complement, Verified ORF, "Nucleotide pyrophosphatase/phosphodiesterase family member; mediates extracellular nucleotide phosphate hydrolysis along with Npp2p and Pho5p; activity and expression enhanced during conditions of phosphate starvation" |
| 589 | YCR027C | RHB1 SGDID:S000000622, Chr III from 167995-167366, reverse complement, Verified ORF, "Putative Rheb-related GTPase involved in regulating canavanine resistance and arginine uptake; member of the Ras superfamily of G-proteins" |
| 590 | YCR028C | FEN2 SGDID:S000000623, Chr III from 172420-170882, reverse complement, Verified ORF, "Plasma membrane H+-pantothenate symporter; confers sensitivity to the antifungal agent fenpropimorph" |
| 591 | YCR028C-A | RIM1 SGDID:S000007222, Chr III from 173436-173195,173111-172946, reverse complement, Verified ORF, "Single-stranded DNA-binding protein essential for mitochondrial genome maintenance; involved in mitochondrial DNA replication" |
| 592 | YCR030C | SYP1 SGDID:S000000626, Chr III from 176434-173822, reverse complement, Verified ORF, "Protein with a potential role in actin cytoskeletal organization; overexpression suppresses a pfy1 (profilin) null mutation" |
| 593 | YCR031C | RPS14A SGDID:S000000627, Chr III from 178216-178210,177902-177496, reverse complement, Verified ORF, "Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Bp and similar to E. coli S11 and rat S14 ribosomal proteins" |
| 594 | YCR032W | BPH1 SGDID:S000000628, Chr III from 179516-186019, Verified ORF, "PProtein homologous to human Chediak-Higashi syndrome and murine Beige proteins, which are implicated in disease syndromes due to defective lysosomal trafficking; mutant phenotype and genetic interactions suggest a role in protein sorting" |
| 595 | YCR033W | SNT1 SGDID:S000000629, Chr III from 186485-190165, Verified ORF, "Subunit of the Set3C deacetylase complex that interacts directly with the Set3C subunit, Sif2p; putative DNA-binding protein" |
| 596 | YCR034W | FEN1 SGDID:S000000630, Chr III from 190588-191631, Verified ORF, "Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway" |
| 597 | YCR035C | RRP43 SGDID:S000000631, Chr III from 193014-191830, reverse complement, Verified ORF, "Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex with Rrp41p, Rrp42p, Rrp4p and Dis3p; required for efficient maturation of 5.8S, 18S and 25S rRNA" |
| 598 | YCR036W | RBK1 SGDID:S000000632, Chr III from 193293-194294, Verified ORF, "Putative ribokinase" |
| 599 | YCR037C | PHO87 SGDID:S000000633, Chr III from 197181-194410, reverse complement, Verified ORF, "Low-affinity inorganic phosphate (Pi) transporter, involved in activation of PHO pathway; expression is independent of Pi concentration and Pho4p activity; contains 12 membrane-spanning segments" |
| 600 | YCR038C | BUD5 SGDID:S000000634, Chr III from 199545-197617, reverse complement, Verified ORF, "GTP/GDP exchange factor for Rsr1p (Bud1p) required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types" |
| 601 | YCR039C | MATALPHA2 SGDID:S000000635, Chr III from 200174-199542, reverse complement, Verified ORF, "Homeobox-domain protein that, with Mcm1p, represses a-specific genes in haploids; acts with A1p to repress transcription of haploid-specific genes in diploids; one of two genes encoded by the MATalpha mating type cassette" |
| 602 | YCR040W | MATALPHA1 SGDID:S000000636, Chr III from 200438-200965, Verified ORF, "Transcriptional co-activator involved in regulation of mating-type-specific gene expression; targets the transcription factor Mcm1p to the promoters of alpha-specific genes; one of two genes encoded by the MATalpha mating type cassette" |
| 603 | YCR042C | TAF2 SGDID:S000000638, Chr III from 205393-201170, reverse complement, Verified ORF, "TFIID subunit (150 kDa), involved in RNA polymerase II transcription initiation" |
| 604 | YCR043C | YCR043C SGDID:S000000639, Chr III from 206640-206257, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi apparatus; YCR043C is not an essential gene" |
| 605 | YCR044C | PER1 SGDID:S000000640, Chr III from 207946-206873, reverse complement, Verified ORF, "Protein of the endoplasmic reticulum, required for GPI-phospholipase A2 activity that remodels the GPI anchor as a prerequisite for association of GPI-anchored proteins with lipid rafts; functionally complemented by human ortholog PERLD1" |
| 606 | YCR045C | YCR045C SGDID:S000000641, Chr III from 209606-208131, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 607 | YCR046C | IMG1 SGDID:S000000642, Chr III from 210419-209910, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit, required for respiration and for maintenance of the mitochondrial genome" |
| 608 | YCR047C | BUD23 SGDID:S000000643, Chr III from 211541-210714, reverse complement, Verified ORF, "Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern" |
| 609 | YCR048W | ARE1 SGDID:S000000644, Chr III from 211925-213757, Verified ORF, "Acyl-CoA:sterol acyltransferase, isozyme of Are2p; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the absence of oxygen" |
| 610 | YCR050C | YCR050C SGDID:S000000646, Chr III from 213768-213460, reverse complement, Uncharacterized ORF, "Non-essential protein of unknown function; deletion mutant is synthetically sick or lethal with alpha-synuclein" |
| 611 | YCR051W | YCR051W SGDID:S000000647, Chr III from 214067-214735, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; contains ankyrin (Ank) repeats; YCR051W is not an essential gene" |
| 612 | YCR052W | RSC6 SGDID:S000000648, Chr III from 214990-216441, Verified ORF, "Component of the RSC chromatin remodeling complex; essential for mitotic growth; homolog of SWI/SNF subunit Swp73p" |
| 613 | YCR053W | THR4 SGDID:S000000649, Chr III from 216693-218237, Verified ORF, "Threonine synthase, conserved protein that catalyzes formation of threonine from 0-phosphohomoserine; expression is regulated by the GCN4-mediated general amino acid control pathway" |
| 614 | YCR054C | CTR86 SGDID:S000000650, Chr III from 220063-218372, reverse complement, Verified ORF, "Essential protein of unknown function; upstream region contains a Gcn4p responsive site suggesting a possible role in amino acid biosynthesis" |
| 615 | YCR057C | PWP2 SGDID:S000000653, Chr III from 223224-220453, reverse complement, Verified ORF, "Conserved 90S pre-ribosomal component essential for proper endonucleolytic cleavage of the 35 S rRNA precursor at A0, A1, and A2 sites; contains eight WD-repeats; PWP2 deletion leads to defects in cell cycle and bud morphogenesis" |
| 616 | YCR059C | YIH1 SGDID:S000000655, Chr III from 224226-223450, reverse complement, Verified ORF, "Protein that inhibits activation of Gcn2p, an eIF2 alpha subunit protein kinase, by competing for Gcn1p binding, thus impacting gene expression in response to starvation; has sequence and functional similarity to the mouse IMPACT gene" |
| 617 | YCR060W | TAH1 SGDID:S000000656, Chr III from 224395-224730, Verified ORF, "HSP90 cofactor; interacts with Hsp82p, Pih1p, Rvb1 and Rvb2, contains a single TPR domain with at least two TPR motifs" |
| 618 | YCR061W | YCR061W SGDID:S000000657, Chr III from 225559-227454, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; induced by treatment with 8-methoxypsoralen and UVA irradiation" |
| 619 | YCR063W | BUD31 SGDID:S000000659, Chr III from 228314-228787, Verified ORF, "Protein involved in bud-site selection; analysis of integrated high-throughput datasets predicts an involvement in RNA splicing; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern" |
| 620 | YCR065W | HCM1 SGDID:S000000661, Chr III from 229306-231000, Verified ORF, "Forkhead transcription factor that drives S-phase specific expression of genes involved in chromosome segregation, spindle dynamics, and budding; suppressor of calmodulin mutants with specific SPB assembly defects; telomere maintenance role" |
| 621 | YCR066W | RAD18 SGDID:S000000662, Chr III from 231496-232959, Verified ORF, "Protein involved in postreplication repair; binds single-stranded DNA and has single-stranded DNA dependent ATPase activity; forms heterodimer with Rad6p; contains RING-finger motif" |
| 622 | YCR067C | SED4 SGDID:S000000663, Chr III from 236318-233121, reverse complement, Verified ORF, "Integral endoplasmic reticulum membrane protein, functions as a positive regulator of Sar1p probably through inhibition of GTPase activation by Sec23p; binds Sec16p, participates in vesicle formation, similar to Sec12p" |
| 623 | YCR068W | ATG15 SGDID:S000000664, Chr III from 237210-238772, Verified ORF, "Lipase, required for intravacuolar lysis of autophagosomes; located in the endoplasmic reticulum membrane and targeted to intravacuolar vesicles during autophagy via the multivesicular body (MVB) pathway" |
| 624 | YCR069W | CPR4 SGDID:S000000665, Chr III from 239051-240007, Verified ORF, "Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway" |
| 625 | YCR071C | IMG2 SGDID:S000000667, Chr III from 240539-240099, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 626 | YCR072C | RSA4 SGDID:S000000668, Chr III from 242348-240801, reverse complement, Verified ORF, "WD-repeat protein involved in ribosome biogenesis; may interact with ribosomes; required for maturation and efficient intra-nuclear transport or pre-60S ribosomal subunits, localizes to the nucleolus" |
| 627 | YCR073C | SSK22 SGDID:S000000669, Chr III from 246580-242585, reverse complement, Verified ORF, "MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; functionally redundant with, and homologous to, Ssk2p; interacts with and is activated by Ssk1p; phosphorylates Pbs2p" |
| 628 | YCR073W-A | SOL2 SGDID:S000000718, Chr III from 246960-247907, Verified ORF, "Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol1p, Sol3p, and Sol4p" |
| 629 | YCR075C | ERS1 SGDID:S000000671, Chr III from 248812-248030, reverse complement, Verified ORF, "Protein with similarity to human cystinosin, which is a H(+)-driven transporter involved in L-cystine export from lysosomes and implicated in the disease cystinosis; contains seven transmembrane domains" |
| 630 | YCR075W-A | YCR075W-A SGDID:S000028519, Chr III from 248972-249199, Uncharacterized ORF, "Putative protein of unknown function; identified by homology to Ashbya gossypii" |
| 631 | YCR076C | YCR076C SGDID:S000000672, Chr III from 250042-249290, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YCR076C is not an essential gene" |
| 632 | YCR077C | PAT1 SGDID:S000000673, Chr III from 252625-250235, reverse complement, Verified ORF, "Topoisomerase II-associated deadenylation-dependent mRNA-decapping factor; also required for faithful chromosome transmission, maintenance of rDNA locus stability, and protection of mRNA 3'-UTRs from trimming; functionally linked to Pab1p" |
| 633 | YCR079W | PTC6 SGDID:S000002133, Chr III from 252842-254170, Verified ORF, "Mitochondrial protein phosphatase of type 2C with similarity to mammalian PP1Ks; involved in mitophagy; null mutant is sensitive to rapamycin and has decreased phosphorylation of the Pda1 subunit of pyruvate dehydrogenase" |
| 634 | YCR081W | SRB8 SGDID:S000000677, Chr III from 254368-258651, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in glucose repression" |
| 635 | YCR082W | AHC2 SGDID:S000000678, Chr III from 258880-259266, Verified ORF, "Protein of unknown function, putative transcriptional regulator; proposed to be a Ada Histone acetyltransferase complex component; GFP tagged protein is localized to the cytoplasm and nucleus" |
| 636 | YCR083W | TRX3 SGDID:S000000679, Chr III from 259575-259958, Verified ORF, "Mitochondrial thioredoxin, highly conserved oxidoreductase required to maintain the redox homeostasis of the cell, forms the mitochondrial thioredoxin system with Trr2p, redox state is maintained by both Trr2p and Glr1p" |
| 637 | YCR084C | TUP1 SGDID:S000000680, Chr III from 262449-260308, reverse complement, Verified ORF, "General repressor of transcription, forms complex with Cyc8p, involved in the establishment of repressive chromatin structure through interactions with histones H3 and H4, appears to enhance expression of some genes" |
| 638 | YCR086W | CSM1 SGDID:S000000682, Chr III from 263389-263961, Verified ORF, "Nucleolar protein that forms a complex with Lrs4p which binds Mam1p at kinetochores during meiosis I to mediate accurate chromosome segregation, may be involved in premeiotic DNA replication; possible role in telomere maintenance" |
| 639 | YCR087C-A | YCR087C-A SGDID:S000007223, Chr III from 264464-264003, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus; YCR087C-A is not an essential gene" |
| 640 | YCR088W | ABP1 SGDID:S000000684, Chr III from 265065-266843, Verified ORF, "Actin-binding protein of the cortical actin cytoskeleton, important for activation of the Arp2/3 complex that plays a key role actin in cytoskeleton organization" |
| 641 | YCR089W | FIG2 SGDID:S000000685, Chr III from 267431-272260, Verified ORF, "Cell wall adhesin, expressed specifically during mating; may be involved in maintenance of cell wall integrity during mating" |
| 642 | YCR090C | YCR090C SGDID:S000000686, Chr III from 272860-272312, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YCR090C is not an essential gene" |
| 643 | YCR091W | KIN82 SGDID:S000000687, Chr III from 274401-276563, Verified ORF, "Putative serine/threonine protein kinase, most similar to cyclic nucleotide-dependent protein kinase subfamily and the protein kinase C subfamily" |
| 644 | YCR092C | MSH3 SGDID:S000000688, Chr III from 279817-276761, reverse complement, Verified ORF, "Mismatch repair protein, forms dimers with Msh2p that mediate repair of insertion or deletion mutations and removal of nonhomologous DNA ends, contains a PCNA (Pol30p) binding motif required for genome stability" |
| 645 | YCR093W | CDC39 SGDID:S000000689, Chr III from 280114-286440, Verified ORF, "Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor" |
| 646 | YCR094W | CDC50 SGDID:S000000690, Chr III from 286759-287934, Verified ORF, "Endosomal protein that regulates cell polarity, controls polarized growth; similar to Ynr048wp and Lem3p" |
| 647 | YCR095C | YCR095C SGDID:S000000691, Chr III from 289255-288167, reverse complement, Uncharacterized ORF, "Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts" |
| 648 | YCR095W-A | YCR095W-A SGDID:S000029724, Chr III from 289636-289794, Uncharacterized ORF, "Putative protein of unknown function" |
| 649 | YCR096C | HMRA2 SGDID:S000000692, Chr III from 293535-293176, reverse complement, Verified silenced_gene ORF, "Silenced copy of a2 at HMR; similarity to Alpha2p; required along with a1p for inhibiting expression of the HO endonuclease in a/alpha HO/HO diploid cells with an active mating-type interconversion system" |
| 650 | YCR097W | HMRA1 SGDID:S000000694, Chr III from 293832-293936,293991-294236,294289-294318, Verified silenced_gene ORF, "Silenced copy of a1 at HMR; homeobox corepressor that interacts with Alpha2p to repress haploid-specific gene transcription in diploid cells" |
| 651 | YCR098C | GIT1 SGDID:S000000695, Chr III from 298602-297046, reverse complement, Verified ORF, "Plasma membrane permease, mediates uptake of glycerophosphoinositol and glycerophosphocholine as sources of the nutrients inositol and phosphate; expression and transport rate are regulated by phosphate and inositol availability" |
| 652 | YCR099C | YCR099C SGDID:S000000696, Chr III from 301296-300829, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 653 | YCR100C | YCR100C SGDID:S000000697, Chr III from 302218-301268, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 654 | YCR101C | YCR101C SGDID:S000000698, Chr III from 303027-302479, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; localizes to the membrane fraction; YCR101C is not an essential gene" |
| 655 | YCR102C | YCR102C SGDID:S000000699, Chr III from 305464-304358, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; involved in copper metabolism; similar to C.carbonum toxD gene; YCR102C is not an essential gene" |
| 656 | YCR104W | PAU3 SGDID:S000000701, Chr III from 307798-308172, Verified ORF, "Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme" |
| 657 | YCR105W | ADH7 SGDID:S000000702, Chr III from 309067-310152, Verified ORF, "NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance" |
| 658 | YCR106W | RDS1 SGDID:S000000703, Chr III from 310955-313453, Verified ORF, "Zinc cluster transcription factor involved in conferring resistance to cycloheximide" |
| 659 | YCR107W | AAD3 SGDID:S000000704, Chr III from 313887-314978, Verified ORF, "Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role" |
| 660 | YCR108C | YCR108C SGDID:S000028536, Chr III from 316185-315994, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 661 | YDL001W | RMD1 SGDID:S000002159, Chr IV from 447982-449274, Verified ORF, "Cytoplasmic protein required for sporulation" |
| 662 | YDL002C | NHP10 SGDID:S000002160, Chr IV from 447576-446965, reverse complement, Verified ORF, "Protein related to mammalian high mobility group proteins; likely component of the INO80 complex, which is an ATP-dependent chromatin-remodeling complex" |
| 663 | YDL003W | MCD1 SGDID:S000002161, Chr IV from 444681-446381, Verified ORF, "Essential protein required for sister chromatid cohesion in mitosis and meiosis; subunit of the cohesin complex; expression is cell cycle regulated and peaks in S phase" |
| 664 | YDL004W | ATP16 SGDID:S000002162, Chr IV from 443027-443509, Verified ORF, "Delta subunit of the central stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" |
| 665 | YDL005C | MED2 SGDID:S000002163, Chr IV from 442307-441012, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation" |
| 666 | YDL006W | PTC1 SGDID:S000002164, Chr IV from 439907-440752, Verified ORF, "Type 2C protein phosphatase (PP2C); inactivates the osmosensing MAPK cascade by dephosphorylating Hog1p; mutation delays mitochondrial inheritance; deletion reveals defects in precursor tRNA splicing, sporulation and cell separation" |
| 667 | YDL007C-A | YDL007C-A SGDID:S000113557, Chr IV from 436822-436565, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 668 | YDL007W | RPT2 SGDID:S000002165, Chr IV from 438045-439358, Verified ORF, "One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for normal peptide hydrolysis by the core 20S particle" |
| 669 | YDL008W | APC11 SGDID:S000002166, Chr IV from 433495-433992, Verified ORF, "Catalytic core subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" |
| 670 | YDL010W | GRX6 SGDID:S000002168, Chr IV from 432328-433023, Verified ORF, "Cis-golgi localized monothiol glutaredoxin that binds an iron-sulfur cluster; more similar in activity to dithiol than other monothiol glutaredoxins; involved in the oxidative stress response; functional overlap with GRX6" |
| 671 | YDL012C | YDL012C SGDID:S000002170, Chr IV from 431515-431471,431384-431106, reverse complement, Uncharacterized ORF, "Plasma membrane protein of unknown function; YDL012C is not an essential gene" |
| 672 | YDL013W | SLX5 SGDID:S000002171, Chr IV from 429065-430924, Verified ORF, "Subunit of the Slx5-Slx8 substrate-specific ubiquitin ligase complex; stimulated by prior attachment of SUMO to the substrate" |
| 673 | YDL014W | NOP1 SGDID:S000002172, Chr IV from 427362-428345, Verified ORF, "Nucleolar protein, component of the small subunit processome complex, which is required for processing of pre-18S rRNA; has similarity to mammalian fibrillarin" |
| 674 | YDL015C | TSC13 SGDID:S000002173, Chr IV from 426932-426000, reverse complement, Verified ORF, "Enoyl reductase that catalyzes the last step in each cycle of very long chain fatty acid elongation, localizes to the ER, highly enriched in a structure marking nuclear-vacuolar junctions, coimmunoprecipitates with elongases Fen1p and Sur4p" |
| 675 | YDL017W | CDC7 SGDID:S000002175, Chr IV from 424207-425730, Verified ORF, "DDK (Dbf4-dependent kinase) catalytic subunit required for firing origins and replication fork progression in mitosis through phosphorylation of Mcm2-7p complexes and Cdc45p; kinase activity correlates with cyclical DBF4 expression" |
| 676 | YDL018C | ERP3 SGDID:S000002176, Chr IV from 423508-422831, reverse complement, Verified ORF, "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport" |
| 677 | YDL019C | OSH2 SGDID:S000002177, Chr IV from 421512-417661, reverse complement, Verified ORF, "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability" |
| 678 | YDL020C | RPN4 SGDID:S000002178, Chr IV from 416706-415111, reverse complement, Verified ORF, "Transcription factor that stimulates expression of proteasome genes; Rpn4p levels are in turn regulated by the 26S proteasome in a negative feedback control mechanism; RPN4 is transcriptionally regulated by various stress responses" |
| 679 | YDL021W | GPM2 SGDID:S000002179, Chr IV from 413951-414886, Verified ORF, "Homolog of Gpm1p phosphoglycerate mutase which converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; may be non-functional derivative of a gene duplication event" |
| 680 | YDL022W | GPD1 SGDID:S000002180, Chr IV from 411823-412998, Verified ORF, "NAD-dependent glycerol-3-phosphate dehydrogenase, key enzyme of glycerol synthesis, essential for growth under osmotic stress; expression regulated by high-osmolarity glycerol response pathway; homolog of Gpd2p" |
| 681 | YDL024C | DIA3 SGDID:S000002182, Chr IV from 409855-408449, reverse complement, Verified ORF, "Protein of unknown function, involved in invasive and pseudohyphal growth" |
| 682 | YDL025C | YDL025C SGDID:S000002183, Chr IV from 407204-405342, reverse complement, Uncharacterized ORF, "Putative protein kinase, potentially phosphorylated by Cdc28p; YDL025C is not an essential gene" |
| 683 | YDL027C | YDL027C SGDID:S000002185, Chr IV from 404955-403693, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YDL027C is not an essential gene" |
| 684 | YDL028C | MPS1 SGDID:S000002186, Chr IV from 403289-400995, reverse complement, Verified ORF, "Dual-specificity kinase required for spindle pole body (SPB) duplication and spindle checkpoint function; substrates include SPB proteins Spc42p, Spc110p, and Spc98p, mitotic exit network protein Mob1p, and checkpoint protein Mad1p" |
| 685 | YDL029W | ARP2 SGDID:S000002187, Chr IV from 399338-399359,399483-400636, Verified ORF, "Essential component of the Arp2/3 complex, which is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity" |
| 686 | YDL030W | PRP9 SGDID:S000002188, Chr IV from 397535-399127, Verified ORF, "Subunit of the SF3a splicing factor complex, required for spliceosome assembly; acts after the formation of the U1 snRNP-pre-mRNA complex" |
| 687 | YDL031W | DBP10 SGDID:S000002189, Chr IV from 394215-397202, Verified ORF, "Putative ATP-dependent RNA helicase of the DEAD-box protein family, constituent of 66S pre-ribosomal particles; essential protein involved in ribosome biogenesis" |
| 688 | YDL033C | SLM3 SGDID:S000002191, Chr IV from 393910-392657, reverse complement, Verified ORF, "tRNA-specific 2-thiouridylase, responsible for 2-thiolation of the wobble base of mitochondrial tRNAs; human ortholog is implicated in myoclonus epilepsy associated with ragged red fibers (MERRF)" |
| 689 | YDL035C | GPR1 SGDID:S000002193, Chr IV from 392055-389170, reverse complement, Verified ORF, "Plasma membrane G protein coupled receptor (GPCR) that interacts with the heterotrimeric G protein alpha subunit, Gpa2p, and with Plc1p; sensor that integrates nutritional signals with the modulation of cell fate via PKA and cAMP synthesis" |
| 690 | YDL036C | PUS9 SGDID:S000002194, Chr IV from 388899-387511, reverse complement, Verified ORF, "Mitochondrial tRNA pseudouridine synthase involved in pseudouridylation of mitochondrial tRNAs at position 32" |
| 691 | YDL037C | BSC1 SGDID:S000002195, Chr IV from 385585-384599, reverse complement, Verified ORF, "Protein of unconfirmed function, similar to cell surface flocculin Muc1p; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression" |
| 692 | YDL039C | PRM7 SGDID:S000002197, Chr IV from 384079-381983, reverse complement, Verified ORF, "Pheromone-regulated protein, predicted to have one transmembrane segment; promoter contains Gcn4p binding elements" |
| 693 | YDL040C | NAT1 SGDID:S000002198, Chr IV from 381435-378871, reverse complement, Verified ORF, "Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing" |
| 694 | YDL042C | SIR2 SGDID:S000002200, Chr IV from 378442-376754, reverse complement, Verified ORF, "Conserved NAD+ dependent histone deacetylase of the Sirtuin family involved in regulation of lifespan; plays roles in silencing at HML, HMR, telomeres, and the rDNA locus; negatively regulates initiation of DNA replication" |
| 695 | YDL043C | PRP11 SGDID:S000002201, Chr IV from 376477-375677, reverse complement, Verified ORF, "Subunit of the SF3a splicing factor complex, required for spliceosome assembly" |
| 696 | YDL044C | MTF2 SGDID:S000002202, Chr IV from 375286-373964, reverse complement, Verified ORF, "Mitochondrial matrix protein that interacts with an N-terminal region of mitochondrial RNA polymerase (Rpo41p) and couples RNA processing and translation to transcription" |
| 697 | YDL045C | FAD1 SGDID:S000002203, Chr IV from 373605-372685, reverse complement, Verified ORF, "Flavin adenine dinucleotide (FAD) synthetase, performs the second step in synthesis of FAD from riboflavin" |
| 698 | YDL045W-A | MRP10 SGDID:S000006430, Chr IV from 372245-372532, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 699 | YDL046W | NPC2 SGDID:S000002204, Chr IV from 371237-371758, Verified ORF, "Functional homolog of human NPC2/He1, which is a cholesterol-binding protein whose deficiency causes Niemann-Pick type C2 disease involving retention of cholesterol in lysosomes" |
| 700 | YDL047W | SIT4 SGDID:S000002205, Chr IV from 369769-370704, Verified ORF, "Type 2A-related serine-threonine phosphatase that functions in the G1/S transition of the mitotic cycle; cytoplasmic and nuclear protein that modulates functions mediated by Pkc1p including cell wall and actin cytoskeleton organization" |
| 701 | YDL048C | STP4 SGDID:S000002206, Chr IV from 368211-366739, reverse complement, Verified ORF, "Protein containing a Kruppel-type zinc-finger domain; has similarity to Stp1p, Stp2p, and Stp3p" |
| 702 | YDL049C | KNH1 SGDID:S000002207, Chr IV from 365874-365068, reverse complement, Verified ORF, "Protein with similarity to Kre9p, which is involved in cell wall beta 1,6-glucan synthesis; overproduction suppresses growth defects of a kre9 null mutant" |
| 703 | YDL051W | LHP1 SGDID:S000002209, Chr IV from 363952-364779, Verified ORF, "RNA binding protein required for maturation of tRNA and snRNA precursors; acts as a molecular chaperone for RNAs transcribed by polymerase III; homologous to human La (SS-B) autoantigen" |
| 704 | YDL052C | SLC1 SGDID:S000002210, Chr IV from 363583-362672, reverse complement, Verified ORF, "1-acyl-sn-gylcerol-3-phosphate acyltransferase, catalyzes the acylation of lysophosphatidic acid to form phosphatidic acid, a key intermediate in lipid metabolism; enzymatic activity detected in lipid particles and microsomes" |
| 705 | YDL053C | PBP4 SGDID:S000002211, Chr IV from 362256-361699, reverse complement, Verified ORF, "Pbp1p binding protein, interacts strongly with Pab1p-binding protein 1 (Pbp1p) in the yeast two-hybrid system; also interacts with Lsm12p in a copurification assay" |
| 706 | YDL054C | MCH1 SGDID:S000002212, Chr IV from 361285-359825, reverse complement, Verified ORF, "Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport" |
| 707 | YDL055C | PSA1 SGDID:S000002213, Chr IV from 356759-355674, reverse complement, Verified ORF, "GDP-mannose pyrophosphorylase (mannose-1-phosphate guanyltransferase), synthesizes GDP-mannose from GTP and mannose-1-phosphate in cell wall biosynthesis; required for normal cell wall structure" |
| 708 | YDL056W | MBP1 SGDID:S000002214, Chr IV from 352877-355378, Verified ORF, "Transcription factor involved in regulation of cell cycle progression from G1 to S phase, forms a complex with Swi6p that binds to MluI cell cycle box regulatory element in promoters of DNA synthesis genes" |
| 709 | YDL057W | YDL057W SGDID:S000002215, Chr IV from 351434-352420, Uncharacterized ORF, "Putative protein of unknown function; YDL057W is not an essential gene" |
| 710 | YDL058W | USO1 SGDID:S000002216, Chr IV from 345665-351037, Verified ORF, "Essential protein involved in intracellular protein transport, coiled-coil protein necessary for transport from ER to Golgi; required for assembly of the ER-to-Golgi SNARE complex" |
| 711 | YDL059C | RAD59 SGDID:S000002217, Chr IV from 344953-344237, reverse complement, Verified ORF, "Protein involved in the repair of double-strand breaks in DNA during vegetative growth via recombination and single-strand annealing; anneals complementary single-stranded DNA; homologous to Rad52p" |
| 712 | YDL060W | TSR1 SGDID:S000002218, Chr IV from 341619-343985, Verified ORF, "Protein required for processing of 20S pre-rRNA in the cytoplasm, associates with pre-40S ribosomal particles" |
| 713 | YDL061C | RPS29B SGDID:S000002219, Chr IV from 340798-340628, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps29Ap and has similarity to rat S29 and E. coli S14 ribosomal proteins" |
| 714 | YDL063C | YDL063C SGDID:S000002221, Chr IV from 340134-338272, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YDL063C is not an essential gene" |
| 715 | YDL064W | UBC9 SGDID:S000002222, Chr IV from 337487-337524,337635-338070, Verified ORF, "SUMO-conjugating enzyme involved in the Smt3p conjugation pathway; nuclear protein required for S- and M-phase cyclin degradation and mitotic control; involved in proteolysis mediated by the anaphase-promoting complex cyclosome (APCC)" |
| 716 | YDL065C | PEX19 SGDID:S000002223, Chr IV from 337277-336249, reverse complement, Verified ORF, "Chaperone and import receptor for newly-synthesized class I peroxisomal membrane proteins (PMPs), binds PMPs in the cytoplasm and delivers them to the peroxisome for subsequent insertion into the peroxisomal membrane" |
| 717 | YDL066W | IDP1 SGDID:S000002224, Chr IV from 334835-336121, Verified ORF, "Mitochondrial NADP-specific isocitrate dehydrogenase, catalyzes the oxidation of isocitrate to alpha-ketoglutarate; not required for mitochondrial respiration and may function to divert alpha-ketoglutarate to biosynthetic processes" |
| 718 | YDL067C | COX9 SGDID:S000002225, Chr IV from 334396-334217, reverse complement, Verified ORF, "Subunit VIIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain" |
| 719 | YDL069C | CBS1 SGDID:S000002227, Chr IV from 333810-333121, reverse complement, Verified ORF, "Mitochondrial translational activator of the COB mRNA; membrane protein that interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader" |
| 720 | YDL070W | BDF2 SGDID:S000002228, Chr IV from 331025-332941, Verified ORF, "Protein involved in transcription initiation at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf1p" |
| 721 | YDL072C | YET3 SGDID:S000002230, Chr IV from 330447-329836, reverse complement, Verified ORF, "Protein of unknown function; YET3 null mutant decreases the level of secreted invertase; homolog of human BAP31 protein" |
| 722 | YDL073W | YDL073W SGDID:S000002231, Chr IV from 326613-329567, Uncharacterized ORF, "Putative protein of unknown function; YDL073W is not an essential gene" |
| 723 | YDL074C | BRE1 SGDID:S000002232, Chr IV from 326149-324047, reverse complement, Verified ORF, "E3 ubiquitin ligase for Rad6p, required for the ubiquitination of histone H2B, recruitment of Rad6p to promoter chromatin and subsequent methylation of histone H3 (on K4 and K79), contains RING finger domain" |
| 724 | YDL075W | RPL31A SGDID:S000002233, Chr IV from 322226-322282,322704-322988, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Bp and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p" |
| 725 | YDL076C | RXT3 SGDID:S000002234, Chr IV from 321552-320668, reverse complement, Verified ORF, "Subunit of the RPD3L complex; involved in histone deacetylation" |
| 726 | YDL077C | VAM6 SGDID:S000002235, Chr IV from 320120-316971, reverse complement, Verified ORF, "Vacuolar protein that plays a critical role in the tethering steps of vacuolar membrane fusion by facilitating guanine nucleotide exchange on small guanosine triphosphatase Ypt7p" |
| 727 | YDL078C | MDH3 SGDID:S000002236, Chr IV from 316388-315357, reverse complement, Verified ORF, "Peroxisomal malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the glyoxylate cycle" |
| 728 | YDL079C | MRK1 SGDID:S000002237, Chr IV from 314748-314337,314044-312951, reverse complement, Verified ORF, "Glycogen synthase kinase 3 (GSK-3) homolog; one of four GSK-3 homologs in S. cerevisiae that function to activate Msn2p-dependent transcription of stress responsive genes and that function in protein degradation" |
| 729 | YDL080C | THI3 SGDID:S000002238, Chr IV from 312471-310642, reverse complement, Verified ORF, "Probable alpha-ketoisocaproate decarboxylase, may have a role in catabolism of amino acids to long-chain and complex alcohols; required for expression of enzymes involved in thiamine biosynthesis" |
| 730 | YDL081C | RPP1A SGDID:S000002239, Chr IV from 310122-309802, reverse complement, Verified ORF, "Ribosomal stalk protein P1 alpha, involved in the interaction between translational elongation factors and the ribosome; accumulation of P1 in the cytoplasm is regulated by phosphorylation and interaction with the P2 stalk component" |
| 731 | YDL082W | RPL13A SGDID:S000002240, Chr IV from 308424-308427,308793-309388, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl13Bp; not essential for viability; has similarity to rat L13 ribosomal protein" |
| 732 | YDL083C | RPS16B SGDID:S000002241, Chr IV from 307789-307766,307333-306926, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; identical to Rps16Ap and has similarity to E. coli S9 and rat S16 ribosomal proteins" |
| 733 | YDL084W | SUB2 SGDID:S000002242, Chr IV from 305237-306577, Verified ORF, "Component of the TREX complex required for nuclear mRNA export; member of the DEAD-box RNA helicase superfamily and is involved in early and late steps of spliceosome assembly; homolog of the human splicing factor hUAP56" |
| 734 | YDL085C-A | YDL085C-A SGDID:S000007588, Chr IV from 302670-302464, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
| 735 | YDL085W | NDE2 SGDID:S000002243, Chr IV from 303211-304848, Verified ORF, "Mitochondrial external NADH dehydrogenase, catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p are involved in providing the cytosolic NADH to the mitochondrial respiratory chain" |
| 736 | YDL086W | YDL086W SGDID:S000002244, Chr IV from 301413-302234, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YDL086W is not an essential gene" |
| 737 | YDL087C | LUC7 SGDID:S000002245, Chr IV from 300999-300214, reverse complement, Verified ORF, "Essential protein associated with the U1 snRNP complex; splicing factor involved in recognition of 5' splice site; contains two zinc finger motifs; N-terminal zinc finger binds pre-mRNA" |
| 738 | YDL088C | ASM4 SGDID:S000002246, Chr IV from 300003-298417, reverse complement, Verified ORF, "Nuclear pore complex subunit, part of a subcomplex also containing Nup53p, Nup170p, and Pse1p" |
| 739 | YDL089W | YDL089W SGDID:S000002247, Chr IV from 296820-298274, Uncharacterized ORF, "Protein of unknown function; interacts with meiotic division protein Csm1p; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery, potential Cdc28p substrate" |
| 740 | YDL090C | RAM1 SGDID:S000002248, Chr IV from 296329-295034, reverse complement, Verified ORF, "Beta subunit of the CAAX farnesyltransferase (FTase) that prenylates the a-factor mating pheromone and Ras proteins; required for the membrane localization of Ras proteins and a-factor; homolog of the mammalian FTase beta subunit" |
| 741 | YDL091C | UBX3 SGDID:S000002249, Chr IV from 294759-293392, reverse complement, Verified ORF, "UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 742 | YDL092W | SRP14 SGDID:S000002250, Chr IV from 292781-293221, Verified ORF, "Signal recognition particle (SRP) subunit, interacts with the RNA component of SRP to form the Alu domain, which is the region of SRP responsible for arrest of nascent chain elongation during membrane targeting; homolog of mammalian SRP14" |
| 743 | YDL093W | PMT5 SGDID:S000002251, Chr IV from 289909-292140, Verified ORF, "Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt3p, can instead interact with Pmt2p in some conditions; target for new antifungals" |
| 744 | YDL095W | PMT1 SGDID:S000002253, Chr IV from 287059-289512, Verified ORF, "Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt2p, can instead interact with Pmt3p in some conditions; target for new antifungals" |
| 745 | YDL097C | RPN6 SGDID:S000002255, Chr IV from 286695-285391, reverse complement, Verified ORF, "Essential, non-ATPase regulatory subunit of the 26S proteasome lid required for the assembly and activity of the 26S proteasome; the human homolog (S9 protein) partially rescues Rpn6p depletion" |
| 746 | YDL098C | SNU23 SGDID:S000002256, Chr IV from 285165-284581, reverse complement, Verified ORF, "Component of U4/U6.U5 snRNP involved in mRNA splicing via spliceosome" |
| 747 | YDL099W | BUG1 SGDID:S000002257, Chr IV from 283419-284444, Verified ORF, "Cis-golgi localized protein involved in ER to Golgi transport; forms a complex with the mammalian GRASP65 homolog, Grh1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes" |
| 748 | YDL100C | GET3 SGDID:S000002258, Chr IV from 283176-282112, reverse complement, Verified ORF, "Guanine nucleotide exchange factor for Gpa1p; amplifies G protein signaling; subunit of the GET complex, which is involved in Golgi to ER trafficking; has low-level ATPase activity and is involved in resistance to heat and metal stress" |
| 749 | YDL101C | DUN1 SGDID:S000002259, Chr IV from 281848-280307, reverse complement, Verified ORF, "Cell-cycle checkpoint serine-threonine kinase required for DNA damage-induced transcription of certain target genes, phosphorylation of Rad55p and Sml1p, and transient G2/M arrest after DNA damage; also regulates postreplicative DNA repair" |
| 750 | YDL102W | POL3 SGDID:S000002260, Chr IV from 276872-280165, Verified ORF, "Catalytic subunit of DNA polymerase delta; required for chromosomal DNA replication during mitosis and meiosis, intragenic recombination, repair of double strand DNA breaks, and DNA replication during nucleotide excision repair (NER)" |
| 751 | YDL103C | QRI1 SGDID:S000002261, Chr IV from 276581-275148, reverse complement, Verified ORF, "UDP-N-acetylglucosamine pyrophosphorylase, catalyzes the formation of UDP-N-acetylglucosamine (UDP-GlcNAc), which is important in cell wall biosynthesis, protein N-glycosylation, and GPI anchor biosynthesis" |
| 752 | YDL104C | QRI7 SGDID:S000002262, Chr IV from 274876-273653, reverse complement, Uncharacterized ORF, "Putative metalloprotease, similar to O-sialoglycoprotein metallopeptidase from P. haemolytica; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 753 | YDL105W | NSE4 SGDID:S000002263, Chr IV from 272389-273597, Verified ORF, "Nuclear protein that plays a role in the function of the Smc5p-Rhc18p complex" |
| 754 | YDL106C | PHO2 SGDID:S000002264, Chr IV from 271901-270222, reverse complement, Verified ORF, "Homeobox transcription factor; regulatory targets include genes involved in phosphate metabolism; binds cooperatively with Pho4p to the PHO5 promoter; phosphorylation of Pho2p facilitates interaction with Pho4p" |
| 755 | YDL107W | MSS2 SGDID:S000002265, Chr IV from 268921-269976, Verified ORF, "Peripherally bound inner membrane protein of the mitochondrial matrix involved in membrane insertion of C-terminus of Cox2p, interacts genetically and physically with Cox18p" |
| 756 | YDL108W | KIN28 SGDID:S000002266, Chr IV from 267698-267725,267807-268699, Verified ORF, "Serine/threonine protein kinase, subunit of the transcription factor TFIIH; involved in transcription initiation at RNA polymerase II promoters" |
| 757 | YDL109C | YDL109C SGDID:S000002267, Chr IV from 267201-265258, reverse complement, Uncharacterized ORF, "Putative lipase; involved in lipid metabolism; YDL109C is not an essential gene" |
| 758 | YDL110C | TMA17 SGDID:S000002268, Chr IV from 264964-264512, reverse complement, Verified ORF, "Protein of unknown function that associates with ribosomes" |
| 759 | YDL111C | RRP42 SGDID:S000002269, Chr IV from 264110-263313, reverse complement, Verified ORF, "Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex with Rrp4p, Rrp41p, Rrp43p and Dis3p" |
| 760 | YDL112W | TRM3 SGDID:S000002270, Chr IV from 258915-263225, Verified ORF, "2'-O-ribose methyltransferase, catalyzes the ribose methylation of the guanosine nucleotide at position 18 of tRNAs" |
| 761 | YDL113C | ATG20 SGDID:S000002271, Chr IV from 258555-256633, reverse complement, Verified ORF, "Sorting nexin family member required for the cytoplasm-to-vacuole targeting (Cvt) pathway and for endosomal sorting; has a Phox homology domain that binds phosphatidylinositol-3-phosphate; interacts with Snx4p; potential Cdc28p substrate" |
| 762 | YDL114W | YDL114W SGDID:S000002272, Chr IV from 255604-256530, Uncharacterized ORF, "Putative protein of unknown function with similarity to acyl-carrier-protein reductases; YDL114W is not an essential gene" |
| 763 | YDL115C | IWR1 SGDID:S000002273, Chr IV from 255126-255045,254974-253995, reverse complement, Verified ORF, "Protein of unknown function, deletion causes hypersensitivity to the K1 killer toxin" |
| 764 | YDL116W | NUP84 SGDID:S000002274, Chr IV from 251566-253746, Verified ORF, "Subunit of the nuclear pore complex (NPC), forms a subcomplex with Nup85p, Nup120p, Nup145p-C, Sec13p, and Seh1p that plays a role in nuclear mRNA export and NPC biogenesis" |
| 765 | YDL117W | CYK3 SGDID:S000002275, Chr IV from 248581-251238, Verified ORF, "SH3-domain protein located in the mother-bud neck and the cytokinetic actin ring; mutant phenotype and genetic interactions suggest a role in cytokinesis" |
| 766 | YDL118W | YDL118W SGDID:S000002276, Chr IV from 247302-247682, Uncharacterized ORF, "Non-essential protein of unconfirmed function; mutants are defective in telomere maintenance, and are synthetically sick or lethal with alpha-synuclein" |
| 767 | YDL119C | YDL119C SGDID:S000002277, Chr IV from 247612-246689, reverse complement, Uncharacterized ORF, "Putative mitochondrial transport protein; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in purified mitochondria" |
| 768 | YDL120W | YFH1 SGDID:S000002278, Chr IV from 245923-246447, Verified ORF, "Frataxin, regulates mitochondrial iron accumulation; interacts with Isu1p which promotes Fe-S cluster assembly; interacts with electron transport chain components and may influence respiration; human homolog involved in Friedrich's ataxia" |
| 769 | YDL121C | YDL121C SGDID:S000002279, Chr IV from 245582-245133, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic retiuculum; YDL121C is not an essential protein" |
| 770 | YDL122W | UBP1 SGDID:S000002280, Chr IV from 242552-244981, Verified ORF, "Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins; cleaves at the C terminus of ubiquitin fusions irrespective of their size; capable of cleaving polyubiquitin chains" |
| 771 | YDL123W | SNA4 SGDID:S000002281, Chr IV from 241418-241840, Verified ORF, "Protein of unknown function, localized to the vacuolar outer membrane" |
| 772 | YDL124W | YDL124W SGDID:S000002282, Chr IV from 240259-241197, Verified ORF, "NADPH-dependent alpha-keto amide reductase; reduces aromatic alpha-keto amides, aliphatic alpha-keto esters, and aromatic alpha-keto esters; member of the aldo-keto reductase (AKR) family" |
| 773 | YDL125C | HNT1 SGDID:S000002283, Chr IV from 239606-239510,239398-239019, reverse complement, Verified ORF, "Adenosine 5'-monophosphoramidase; interacts physically and genetically with Kin28p, a CDK and TFIIK subunit, and genetically with CAK1; member of the histidine triad (HIT) superfamily of nucleotide-binding proteins and similar to Hint" |
| 774 | YDL126C | CDC48 SGDID:S000002284, Chr IV from 238664-236157, reverse complement, Verified ORF, "ATPase in ER, nuclear membrane and cytosol with homology to mammalian p97; in a complex with Npl4p and Ufd1p participates in retrotranslocation of ubiquitinated proteins from the ER into the cytosol for degradation by the proteasome" |
| 775 | YDL127W | PCL2 SGDID:S000002285, Chr IV from 234927-235853, Verified ORF, "G1 cyclin, associates with Pho85p cyclin-dependent kinase (Cdk) to contribute to entry into the mitotic cell cycle, essential for cell morphogenesis; localizes to sites of polarized cell growth" |
| 776 | YDL128W | VCX1 SGDID:S000002286, Chr IV from 232652-233887, Verified ORF, "Vacuolar H+/Ca2+ exchanger involved in control of cytosolic Ca2+ concentration; has similarity to sodium/calcium exchangers, including the bovine Na+/Ca2+,K+ antiporter" |
| 777 | YDL129W | YDL129W SGDID:S000002287, Chr IV from 231024-231899, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus; YDL129W is not an essential gene" |
| 778 | YDL130W | RPP1B SGDID:S000002288, Chr IV from 229906-230019,230321-230527, Verified ORF, "Ribosomal protein P1 beta, component of the ribosomal stalk, which is involved in interaction of translational elongation factors with ribosome; accumulation is regulated by phosphorylation and interaction with the P2 stalk component" |
| 779 | YDL130W-A | STF1 SGDID:S000007232, Chr IV from 229171-229431, Verified ORF, "Protein involved in regulation of the mitochondrial F1F0-ATP synthase; Stf1p and Stf2p may act as stabilizing factors that enhance inhibitory action of the Inh1p protein" |
| 780 | YDL131W | LYS21 SGDID:S000002289, Chr IV from 227393-228715, Verified ORF, "Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys20p" |
| 781 | YDL132W | CDC53 SGDID:S000002290, Chr IV from 224304-226751, Verified ORF, "Cullin, structural protein of SCF complexes (which also contain Skp1p, Cdc34p, Hrt1p and an F-box protein) involved in ubiquitination; SCF promotes the G1-S transition by targeting G1 cyclins and the Cln-CDK inhibitor Sic1p for degradation" |
| 782 | YDL133C-A | RPL41B SGDID:S000002293, Chr IV from 221801-221724, reverse complement, Verified ORF, "Ribosomal protein L47 of the large (60S) ribosomal subunit, identical to Rpl41Ap and has similarity to rat L41 ribosomal protein; comprised of only 25 amino acids; rpl41a rpl41b double null mutant is viable" |
| 783 | YDL133W | YDL133W SGDID:S000002291, Chr IV from 222427-223740, Uncharacterized ORF, "Putative protein of unknown function" |
| 784 | YDL134C | PPH21 SGDID:S000002292, Chr IV from 220771-219662, reverse complement, Verified ORF, "Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph22p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis" |
| 785 | YDL135C | RDI1 SGDID:S000002294, Chr IV from 219288-218680, reverse complement, Verified ORF, "Rho GDP dissociation inhibitor involved in the localization and regulation of Cdc42p" |
| 786 | YDL136W | RPL35B SGDID:S000002295, Chr IV from 217600-217602,218008-218367, Verified ORF, "Protein component of the large (60S) ribosomal subunit, identical to Rpl35Ap and has similarity to rat L35 ribosomal protein" |
| 787 | YDL137W | ARF2 SGDID:S000002296, Chr IV from 216529-217074, Verified ORF, "ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated formation vesicles in intracellular trafficking within the Golgi; functionally interchangeable with Arf1p" |
| 788 | YDL138W | RGT2 SGDID:S000002297, Chr IV from 213352-215643, Verified ORF, "Plasma membrane glucose receptor, highly similar to Snf3p; both Rgt2p and Snf3p serve as transmembrane glucose sensors generating an intracellular signal that induces expression of glucose transporter (HXT) genes" |
| 789 | YDL139C | SCM3 SGDID:S000002298, Chr IV from 212047-211376, reverse complement, Verified ORF, "Nonhistone component of centromeric chromatin that binds stoichiometrically to CenH3-H4 histones, required for kinetochore assembly; contains nuclear export signal (NES); required for G2/M progression and localization of Cse4p" |
| 790 | YDL140C | RPO21 SGDID:S000002299, Chr IV from 210562-205361, reverse complement, Verified ORF, "RNA polymerase II largest subunit B220, part of central core; phosphorylation of C-terminal heptapeptide repeat domain regulates association with transcription and splicing factors; similar to bacterial beta-prime" |
| 791 | YDL141W | BPL1 SGDID:S000002300, Chr IV from 203040-205112, Verified ORF, "Biotin:apoprotein ligase, covalently modifies proteins with the addition of biotin, required for acetyl-CoA carboxylase (Acc1p) holoenzyme formation" |
| 792 | YDL142C | CRD1 SGDID:S000002301, Chr IV from 202571-201720, reverse complement, Verified ORF, "Cardiolipin synthase; produces cardiolipin, which is an important constituent of mitochondrial membranes; required for normal mitochondrial membrane potential and function" |
| 793 | YDL143W | CCT4 SGDID:S000002302, Chr IV from 199997-201583, Verified ORF, "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" |
| 794 | YDL144C | YDL144C SGDID:S000002303, Chr IV from 199733-198663, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YDL144C is not an essential gene." |
| 795 | YDL145C | COP1 SGDID:S000002304, Chr IV from 198177-194572, reverse complement, Verified ORF, "Alpha subunit of COPI vesicle coatomer complex, which surrounds transport vesicles in the early secretory pathway" |
| 796 | YDL146W | LDB17 SGDID:S000002305, Chr IV from 192751-194226, Verified ORF, "Protein of unknown function; GFP-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; null mutant shows a reduced affinity for the alcian blue dye suggesting a decreased net negative charge of the cell surface" |
| 797 | YDL147W | RPN5 SGDID:S000002306, Chr IV from 190925-192262, Verified ORF, "Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to mammalian p55 subunit and to another S. cerevisiae regulatory subunit, Rpn7p" |
| 798 | YDL148C | NOP14 SGDID:S000002307, Chr IV from 190587-188155, reverse complement, Verified ORF, "Nucleolar protein, forms a complex with Noc4p that mediates maturation and nuclear export of 40S ribosomal subunits; also present in the small subunit processome complex, which is required for processing of pre-18S rRNA" |
| 799 | YDL149W | ATG9 SGDID:S000002308, Chr IV from 184926-187919, Verified ORF, "Transmembrane protein involved in formation of Cvt and autophagic vesicles; cycles between the pre-autophagosomal structure and other cytosolic punctate structures, not found in autophagosomes" |
| 800 | YDL150W | RPC53 SGDID:S000002309, Chr IV from 183344-184612, Verified ORF, "RNA polymerase III subunit C53" |
| 801 | YDL153C | SAS10 SGDID:S000002312, Chr IV from 183019-181187, reverse complement, Verified ORF, "Component of the small (ribosomal) subunit (SSU) processosome required for pre-18S rRNa processing; essential nucleolar protein that, when overproduced, disrupts silencing" |
| 802 | YDL154W | MSH5 SGDID:S000002313, Chr IV from 178335-181040, Verified ORF, "Protein of the MutS family, forms a dimer with Msh4p that facilitates crossovers between homologs during meiosis; msh5-Y823H mutation confers tolerance to DNA alkylating agents; homologs present in C. elegans and humans" |
| 803 | YDL155W | CLB3 SGDID:S000002314, Chr IV from 176774-178057, Verified ORF, "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation" |
| 804 | YDL156W | YDL156W SGDID:S000002315, Chr IV from 174919-176487, Uncharacterized ORF, "Putative protein of unknown function; protein sequence contains three WD domains (WD-40 repeat); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
| 805 | YDL157C | YDL157C SGDID:S000002316, Chr IV from 174589-174233, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 806 | YDL159W | STE7 SGDID:S000002318, Chr IV from 172482-174029, Verified ORF, "Signal transducing MAP kinase kinase involved in pheromone response, where it phosphorylates Fus3p, and in the pseudohyphal/invasive growth pathway, through phosphorylation of Kss1p; phosphorylated by Ste11p, degraded by ubiquitin pathway" |
| 807 | YDL159W-A | YDL159W-A SGDID:S000007599, Chr IV from 172183-172314, Uncharacterized ORF, "Putative protein of unknown function; identified by sequence comparison with hemiascomycetous yeast species" |
| 808 | YDL160C | DHH1 SGDID:S000002319, Chr IV from 171931-170411, reverse complement, Verified ORF, "Cytoplasmic DExD/H-box helicase, stimulates mRNA decapping, coordinates distinct steps in mRNA function and decay, interacts with both the decapping and deadenylase complexes, may have a role in mRNA export and translation" |
| 809 | YDL160C-A | YDL160C-A SGDID:S000028520, Chr IV from 169609-169367, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 810 | YDL161W | ENT1 SGDID:S000002320, Chr IV from 167715-169079, Verified ORF, "Epsin-like protein involved in endocytosis and actin patch assembly and functionally redundant with Ent2p; binds clathrin via a clathrin-binding domain motif at C-terminus" |
| 811 | YDL164C | CDC9 SGDID:S000002323, Chr IV from 167255-164988, reverse complement, Verified ORF, "DNA ligase found in the nucleus and mitochondria, an essential enzyme that joins Okazaki fragments during DNA replication; also acts in nucleotide excision repair, base excision repair, and recombination" |
| 812 | YDL165W | CDC36 SGDID:S000002324, Chr IV from 164291-164866, Verified ORF, "Component of the CCR4-NOT complex, which has multiple roles in regulating mRNA levels including regulation of transcription and destabilizing mRNAs by deadenylation; basal transcription factor" |
| 813 | YDL166C | FAP7 SGDID:S000002325, Chr IV from 164043-163450, reverse complement, Verified ORF, "Essential NTPase required for small ribosome subunit synthesis, mediates processing of the 20S pre-rRNA at site D in the cytoplasm but associates only transiently with 43S preribosomes via Rps14p, may be the endonuclease for site D" |
| 814 | YDL167C | NRP1 SGDID:S000002326, Chr IV from 163155-160996, reverse complement, Verified ORF, "Protein of unknown function, rich in asparagine residues" |
| 815 | YDL168W | SFA1 SGDID:S000002327, Chr IV from 159605-160765, Verified ORF, "Bifunctional enzyme containing both alcohol dehydrogenase and glutathione-dependent formaldehyde dehydrogenase activities, functions in formaldehyde detoxification and formation of long chain and complex alcohols, regulated by Hog1p-Sko1p" |
| 816 | YDL169C | UGX2 SGDID:S000002328, Chr IV from 158736-158065, reverse complement, Verified ORF, "Protein of unknown function, transcript accumulates in response to any combination of stress conditions" |
| 817 | YDL170W | UGA3 SGDID:S000002329, Chr IV from 156319-157905, Verified ORF, "Transcriptional activator necessary for gamma-aminobutyrate (GABA)-dependent induction of GABA genes (such as UGA1, UGA2, UGA4); zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type; localized to the nucleus" |
| 818 | YDL171C | GLT1 SGDID:S000002330, Chr IV from 155641-149204, reverse complement, Verified ORF, "NAD(+)-dependent glutamate synthase (GOGAT), synthesizes glutamate from glutamine and alpha-ketoglutarate; with Gln1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source" |
| 819 | YDL173W | YDL173W SGDID:S000002332, Chr IV from 148192-149079, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YDL173W is not an essential gene" |
| 820 | YDL174C | DLD1 SGDID:S000002333, Chr IV from 147590-145827, reverse complement, Verified ORF, "D-lactate dehydrogenase, oxidizes D-lactate to pyruvate, transcription is heme-dependent, repressed by glucose, and derepressed in ethanol or lactate; located in the mitochondrial inner membrane" |
| 821 | YDL175C | AIR2 SGDID:S000002334, Chr IV from 145519-144485, reverse complement, Verified ORF, "RING finger protein that interacts with the arginine methyltransferase Hmt1p; may regulate methylation of Npl3p, which modulates Npl3p function in mRNA processing and export; has similarity to Air1p" |
| 822 | YDL176W | YDL176W SGDID:S000002335, Chr IV from 142098-144224, Uncharacterized ORF, "Putative protein of unknown function; YDL176W is not an essential gene" |
| 823 | YDL177C | YDL177C SGDID:S000002336, Chr IV from 141722-141210, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; similar to the mouse IMPACT gene; YDL177C is not an essential gene" |
| 824 | YDL178W | DLD2 SGDID:S000002337, Chr IV from 139523-141115, Verified ORF, "D-lactate dehydrogenase, located in the mitochondrial matrix" |
| 825 | YDL179W | PCL9 SGDID:S000002338, Chr IV from 138292-139206, Verified ORF, "Cyclin, forms a functional kinase complex with Pho85p cyclin-dependent kinase (Cdk), expressed in late M/early G1 phase, activated by Swi5p" |
| 826 | YDL180W | YDL180W SGDID:S000002339, Chr IV from 135897-137540, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole" |
| 827 | YDL181W | INH1 SGDID:S000002340, Chr IV from 135180-135437, Verified ORF, "Protein that inhibits ATP hydrolysis by the F1F0-ATP synthase; inhibitory function is enhanced by stabilizing proteins Stf1p and Stf2p; has similarity to Stf1p; has a calmodulin-binding motif and binds calmodulin in vitro" |
| 828 | YDL182W | LYS20 SGDID:S000002341, Chr IV from 133438-134724, Verified ORF, "Homocitrate synthase isozyme, catalyzes the condensation of acetyl-CoA and alpha-ketoglutarate to form homocitrate, which is the first step in the lysine biosynthesis pathway; highly similar to the other isozyme, Lys21p" |
| 829 | YDL183C | YDL183C SGDID:S000002342, Chr IV from 131834-130872, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YDL183C is not an essential gene" |
| 830 | YDL184C | RPL41A SGDID:S000002343, Chr IV from 130485-130408, reverse complement, Verified ORF, "Ribosomal protein L47 of the large (60S) ribosomal subunit, identical to Rpl41Bp and has similarity to rat L41 ribosomal protein; comprised of only 25 amino acids; rpl41a rpl41b double null mutant is viable" |
| 831 | YDL185W | TFP1 SGDID:S000002344, Chr IV from 126788-130003, Verified ORF, "Vacuolar ATPase V1 domain subunit A containing the catalytic nucleotide binding sites; protein precursor undergoes self-catalyzed splicing to yield the extein Tfp1p and the intein Vde (PI-SceI), which is a site-specific endonuclease" |
| 832 | YDL186W | YDL186W SGDID:S000002345, Chr IV from 125617-126450, Uncharacterized ORF, "Putative protein of unknown function; YDL186W is not an essential gene" |
| 833 | YDL188C | PPH22 SGDID:S000002347, Chr IV from 124999-123866, reverse complement, Verified ORF, "Catalytic subunit of protein phosphatase 2A, functionally redundant with Pph21p; methylated at C terminus; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis" |
| 834 | YDL189W | RBS1 SGDID:S000002348, Chr IV from 122217-123590, Verified ORF, "Protein of unknown function, identified as a high copy suppressor of psk1 psk2 mutations that confer temperature-sensitivity for galactose utilization; proposed to bind single-stranded nucleic acids via its R3H domain" |
| 835 | YDL190C | UFD2 SGDID:S000002349, Chr IV from 121593-118708, reverse complement, Verified ORF, "Ubiquitin chain assembly factor (E4) that cooperates with a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2), and a ubiquitin protein ligase (E3) to conjugate ubiquitin to substrates; also functions as an E3" |
| 836 | YDL191W | RPL35A SGDID:S000002350, Chr IV from 117665-117667,118159-118518, Verified ORF, "Protein component of the large (60S) ribosomal subunit, identical to Rpl35Bp and has similarity to rat L35 ribosomal protein" |
| 837 | YDL192W | ARF1 SGDID:S000002351, Chr IV from 116322-116867, Verified ORF, "ADP-ribosylation factor, GTPase of the Ras superfamily involved in regulation of coated vesicle formation in intracellular trafficking within the Golgi; functionally interchangeable with Arf2p" |
| 838 | YDL193W | NUS1 SGDID:S000002352, Chr IV from 114673-115800, Verified ORF, "Prenyltransferase, required for cell viability; involved in protein trafficking" |
| 839 | YDL194W | SNF3 SGDID:S000002353, Chr IV from 111581-114235, Verified ORF, "Plasma membrane glucose sensor that regulates glucose transport; has 12 predicted transmembrane segments; long cytoplasmic C-terminal tail is required for low glucose induction of hexose transporter genes HXT2 and HXT4" |
| 840 | YDL195W | SEC31 SGDID:S000002354, Chr IV from 107209-111030, Verified ORF, "Essential phosphoprotein component (p150) of the COPII coat of secretory pathway vesicles, in complex with Sec13p; required for ER-derived transport vesicle formation" |
| 841 | YDL197C | ASF2 SGDID:S000002356, Chr IV from 106495-104918, reverse complement, Verified ORF, "Anti-silencing protein that causes derepression of silent loci when overexpressed" |
| 842 | YDL198C | GGC1 SGDID:S000002357, Chr IV from 104552-103650, reverse complement, Verified ORF, "Mitochondrial GTP/GDP transporter, essential for mitochondrial genome maintenance; has a role in mitochondrial iron transport; member of the mitochondrial carrier family" |
| 843 | YDL199C | YDL199C SGDID:S000002358, Chr IV from 103354-101291, reverse complement, Uncharacterized ORF, "Putative transporter, member of the sugar porter family" |
| 844 | YDL200C | MGT1 SGDID:S000002359, Chr IV from 101068-100502, reverse complement, Verified ORF, "DNA repair methyltransferase (6-O-methylguanine-DNA methylase) involved in protection against DNA alkylation damage" |
| 845 | YDL201W | TRM8 SGDID:S000002360, Chr IV from 99562-100422, Verified ORF, "Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA" |
| 846 | YDL202W | MRPL11 SGDID:S000002361, Chr IV from 98476-99225, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 847 | YDL203C | YDL203C SGDID:S000002362, Chr IV from 97954-96083, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in purified mitochondria" |
| 848 | YDL204W | RTN2 SGDID:S000002363, Chr IV from 94606-95787, Verified ORF, "Protein of unknown function; has similarity to mammalian reticulon proteins; member of the RTNLA (reticulon-like A) subfamily" |
| 849 | YDL205C | HEM3 SGDID:S000002364, Chr IV from 93746-92763, reverse complement, Verified ORF, "Phorphobilinogen deaminase, catalyzes the conversion of 4-porphobilinogen to hydroxymethylbilane, the third step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; expression is regulated by Hap2p-Hap3p" |
| 850 | YDL206W | YDL206W SGDID:S000002365, Chr IV from 90177-92465, Uncharacterized ORF, "Putative protein of unknown function; YDL206W is not an essential protein" |
| 851 | YDL207W | GLE1 SGDID:S000002366, Chr IV from 88249-89865, Verified ORF, "Cytoplasmic nucleoporin required for polyadenylated RNA export but not for protein import; component of Nup82p nuclear pore subcomplex; contains a nuclear export signal" |
| 852 | YDL208W | NHP2 SGDID:S000002367, Chr IV from 87513-87983, Verified ORF, "Nuclear protein related to mammalian high mobility group (HMG) proteins, essential for function of H/ACA-type snoRNPs, which are involved in 18S rRNA processing" |
| 853 | YDL209C | CWC2 SGDID:S000002368, Chr IV from 87227-86208, reverse complement, Verified ORF, "Protein involved in pre-mRNA splicing, component of a complex containing Cef1p; interacts with Prp19p; contains an RNA recognition motif; has similarity to S. pombe Cwf2p" |
| 854 | YDL210W | UGA4 SGDID:S000002369, Chr IV from 84271-85986, Verified ORF, "Permease that serves as a gamma-aminobutyrate (GABA) transport protein involved in the utilization of GABA as a nitrogen source; catalyzes the transport of putrescine and delta-aminolevulinic acid (ALA); localized to the vacuolar membrane" |
| 855 | YDL211C | YDL211C SGDID:S000002370, Chr IV from 80413-79295, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole" |
| 856 | YDL212W | SHR3 SGDID:S000002371, Chr IV from 78427-79059, Verified ORF, "Endoplasmic reticulum packaging chaperone, required for incorporation of amino acid permeases into COPII coated vesicles for transport to the cell surface" |
| 857 | YDL213C | NOP6 SGDID:S000002372, Chr IV from 77967-77290, reverse complement, Verified ORF, "Putative RNA-binding protein implicated in ribosome biogenesis; contains an RNA recognition motif (RRM) and has similarity to hydrophilins; NOP6 may be a fungal-specific gene as no homologs have been yet identified in higher eukaryotes" |
| 858 | YDL214C | PRR2 SGDID:S000002373, Chr IV from 76546-74447, reverse complement, Verified ORF, "Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor" |
| 859 | YDL215C | GDH2 SGDID:S000002374, Chr IV from 73919-70641, reverse complement, Verified ORF, "NAD(+)-dependent glutamate dehydrogenase, degrades glutamate to ammonia and alpha-ketoglutarate; expression sensitive to nitrogen catabolite repression and intracellular ammonia levels" |
| 860 | YDL216C | RRI1 SGDID:S000002375, Chr IV from 70320-68998, reverse complement, Verified ORF, "Catalytic subunit of the COP9 signalosome (CSN) complex that acts as an isopeptidase in cleaving the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; metalloendopeptidase involved in the adaptation to pheromone signaling" |
| 861 | YDL217C | TIM22 SGDID:S000002376, Chr IV from 68607-67984, reverse complement, Verified ORF, "Component of the mitochondrial Tim54p-Tim22p complex involved in insertion of polytopic proteins into the inner membrane" |
| 862 | YDL218W | YDL218W SGDID:S000002377, Chr IV from 66494-67447, Uncharacterized ORF, "Putative protein of unknown function; YDL218W transcription is regulated by Azf1p and induced by starvation and aerobic conditions" |
| 863 | YDL219W | DTD1 SGDID:S000002378, Chr IV from 65243-65307,65379-65766, Verified ORF, "D-Tyr-tRNA(Tyr) deacylase, functions in protein translation, may affect nonsense suppression via alteration of the protein synthesis machinery; ubiquitous among eukaryotes" |
| 864 | YDL220C | CDC13 SGDID:S000002379, Chr IV from 65019-62245, reverse complement, Verified ORF, "Single stranded DNA-binding protein found at TG1-3 telomere G-tails; regulates telomere replication through recruitment of specific sub-complexes, but the essential function is telomere capping" |
| 865 | YDL222C | FMP45 SGDID:S000002381, Chr IV from 61802-60873, reverse complement, Verified ORF, "Integral membrane protein localized to mitochondria (untagged protein) and eisosomes, immobile patches at the cortex associated with endocytosis; sporulation and sphingolipid content are altered in mutants; has homologs SUR7 and YNL194C" |
| 866 | YDL223C | HBT1 SGDID:S000002382, Chr IV from 60406-57266, reverse complement, Verified ORF, "Substrate of the Hub1p ubiquitin-like protein that localizes to the shmoo tip (mating projection); mutants are defective for mating projection formation, thereby implicating Hbt1p in polarized cell morphogenesis" |
| 867 | YDL224C | WHI4 SGDID:S000002383, Chr IV from 56347-54398, reverse complement, Verified ORF, "Putative RNA binding protein and partially redundant Whi3p homolog that regulates the cell size requirement for passage through Start and commitment to cell division" |
| 868 | YDL225W | SHS1 SGDID:S000002384, Chr IV from 52446-54101, Verified ORF, "One of five related septins (Cdc3p, Cdc10p, Cdc11p, Cdc12p, Shs1p) that form a cortical filamentous collar at the mother-bud neck which is necessary for normal morphogenesis and cytokinesis" |
| 869 | YDL226C | GCS1 SGDID:S000002385, Chr IV from 52174-51116, reverse complement, Verified ORF, "ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Glo3p" |
| 870 | YDL227C | HO SGDID:S000002386, Chr IV from 48032-46272, reverse complement, Verified ORF, "Site-specific endonuclease required for gene conversion at the MAT locus (homothallic switching) through the generation of a ds DNA break; expression restricted to mother cells in late G1 as controlled by Swi4p-Swi6p, Swi5p and Ash1p" |
| 871 | YDL229W | SSB1 SGDID:S000002388, Chr IV from 44066-45907, Verified ORF, "Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in folding of newly-made polypeptide chains; member of the HSP70 family; interacts with phosphatase subunit Reg1p" |
| 872 | YDL230W | PTP1 SGDID:S000002389, Chr IV from 42701-43708, Verified ORF, "Phosphotyrosine-specific protein phosphatase that dephosphorylates a broad range of substrates in vivo, including Fpr3p; localized to the cytoplasm and the mitochondria" |
| 873 | YDL231C | BRE4 SGDID:S000002390, Chr IV from 42245-38868, reverse complement, Verified ORF, "Zinc finger protein containing five transmembrane domains; null mutant exhibits strongly fragmented vacuoles and sensitivity to brefeldin A, a drug which is known to affect intracellular transport" |
| 874 | YDL232W | OST4 SGDID:S000002391, Chr IV from 38488-38598, Verified ORF, "Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes protein asparagine-linked glycosylation; type I membrane protein required for incorporation of Ost3p or Ost6p into the OST complex" |
| 875 | YDL233W | YDL233W SGDID:S000002392, Chr IV from 36798-38174, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YDL233W is not an essential gene" |
| 876 | YDL234C | GYP7 SGDID:S000002393, Chr IV from 36478-34238, reverse complement, Verified ORF, "GTPase-activating protein for yeast Rab family members including: Ypt7p (most effective), Ypt1p, Ypt31p, and Ypt32p (in vitro); involved in vesicle mediated protein trafficking" |
| 877 | YDL235C | YPD1 SGDID:S000002394, Chr IV from 33918-33415, reverse complement, Verified ORF, "Phosphorelay intermediate protein, phosphorylated by the plasma membrane sensor Sln1p in response to osmotic stress and then in turn phosphorylates the response regulators Ssk1p in the cytosol and Skn7p in the nucleus" |
| 878 | YDL236W | PHO13 SGDID:S000002395, Chr IV from 32296-33234, Verified ORF, "Alkaline phosphatase specific for p-nitrophenyl phosphate, involved in dephosphorylation of histone II-A and casein" |
| 879 | YDL237W | YDL237W SGDID:S000002396, Chr IV from 30657-31829, Uncharacterized ORF, "Putative protein of unknown function; YDL237W is not an essential gene; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media" |
| 880 | YDL238C | GUD1 SGDID:S000002397, Chr IV from 30454-28985, reverse complement, Verified ORF, "Guanine deaminase, a catabolic enzyme of the guanine salvage pathway producing xanthine and ammonia from guanine; activity is low in exponentially-growing cultures but expression is increased in post-diauxic and stationary-phase cultures" |
| 881 | YDL239C | ADY3 SGDID:S000002398, Chr IV from 28775-26403, reverse complement, Verified ORF, "Protein required for spore wall formation, thought to mediate assembly of a Don1p-containing structure at the leading edge of the prospore membrane via interaction with spindle pole body components; potentially phosphorylated by Cdc28p" |
| 882 | YDL240W | LRG1 SGDID:S000002399, Chr IV from 22823-25876, Verified ORF, "Putative GTPase-activating protein (GAP) involved in the Pkc1p-mediated signaling pathway that controls cell wall integrity; appears to specifically regulate 1,3-beta-glucan synthesis" |
| 883 | YDL241W | YDL241W SGDID:S000002400, Chr IV from 20635-21006, Uncharacterized ORF, "Putative protein of unknown function; YDL241W is not an essential gene" |
| 884 | YDL243C | AAD4 SGDID:S000002402, Chr IV from 18566-17577, reverse complement, Verified ORF, "Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase, involved in the oxidative stress response" |
| 885 | YDL244W | THI13 SGDID:S000002403, Chr IV from 16204-17226, Verified ORF, "Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13" |
| 886 | YDL245C | HXT15 SGDID:S000002404, Chr IV from 13360-11657, reverse complement, Verified ORF, "Protein of unknown function with similarity to hexose transporter family members, expression is induced by low levels of glucose and repressed by high levels of glucose" |
| 887 | YDL246C | SOR2 SGDID:S000002405, Chr IV from 9756-8683, reverse complement, Uncharacterized ORF, "Protein of unknown function, computational analysis of large-scale protein-protein interaction data suggests a possible role in fructose or mannose metabolism" |
| 888 | YDL247W | MPH2 SGDID:S000002406, Chr IV from 5985-7814, Verified ORF, "Alpha-glucoside permease, transports maltose, maltotriose, alpha-methylglucoside, and turanose; identical to Mph3p; encoded in a subtelomeric position in a region likely to have undergone duplication" |
| 889 | YDL248W | COS7 SGDID:S000002407, Chr IV from 1802-2953, Verified ORF, "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 890 | YDR001C | NTH1 SGDID:S000002408, Chr IV from 452473-450218, reverse complement, Verified ORF, "Neutral trehalase, degrades trehalose; required for thermotolerance and may mediate resistance to other cellular stresses; may be phosphorylated by Cdc28p" |
| 891 | YDR002W | YRB1 SGDID:S000002409, Chr IV from 453043-453648, Verified ORF, "Ran GTPase binding protein; involved in nuclear protein import and RNA export, ubiquitin-mediated protein degradation during the cell cycle; shuttles between the nucleus and cytoplasm; is essential; homolog of human RanBP1" |
| 892 | YDR003W | RCR2 SGDID:S000002410, Chr IV from 454120-454752, Verified ORF, "Vacuolar protein that presumably functions within the endosomal-vacuolar trafficking pathway, affecting events that determine whether plasma membrane proteins are degraded or routed to the plasma membrane; similar to Rcr1p" |
| 893 | YDR003W-A | YDR003W-A SGDID:S000028819, Chr IV from 454780-454902, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 894 | YDR004W | RAD57 SGDID:S000002411, Chr IV from 455199-456581, Verified ORF, "Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad55p" |
| 895 | YDR005C | MAF1 SGDID:S000002412, Chr IV from 458101-458096,458015-456834, reverse complement, Verified ORF, "Negative regulator of RNA polymerase III; component of several signaling pathways that repress polymerase III transcription in response to changes in cellular environment; targets the initiation factor TFIIIB" |
| 896 | YDR006C | SOK1 SGDID:S000002413, Chr IV from 461245-458540, reverse complement, Verified ORF, "Protein whose overexpression suppresses the growth defect of mutants lacking protein kinase A activity; involved in cAMP-mediated signaling; localized to the nucleus; similar to the mouse testis-specific protein PBS13" |
| 897 | YDR007W | TRP1 SGDID:S000002414, Chr IV from 461840-462514, Verified ORF, "Phosphoribosylanthranilate isomerase that catalyzes the third step in tryptophan biosynthesis; in 2004, the sequence of TRP1 from strain S228C was updated by changing the previously annotated internal STOP (TAA) to serine (TCA)" |
| 898 | YDR009W | GAL3 SGDID:S000002416, Chr IV from 463432-464994, Verified ORF, "Transcriptional regulator involved in activation of the GAL genes in response to galactose; forms a complex with Gal80p to relieve Gal80p inhibition of Gal4p; binds galactose and ATP but does not have galactokinase activity" |
| 899 | YDR011W | SNQ2 SGDID:S000002418, Chr IV from 465917-470422, Verified ORF, "Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter involved in multidrug resistance and resistance to singlet oxygen species" |
| 900 | YDR012W | RPL4B SGDID:S000002419, Chr IV from 471851-472939, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl4Ap and has similarity to E. coli L4 and rat L4 ribosomal proteins" |
| 901 | YDR013W | PSF1 SGDID:S000002420, Chr IV from 473155-473781, Verified ORF, "Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery" |
| 902 | YDR014W | RAD61 SGDID:S000002421, Chr IV from 474044-475987, Verified ORF, "Protein of unknown function; mutation confers radiation sensitivity" |
| 903 | YDR014W-A | HED1 SGDID:S000113613, Chr IV from 477795-478283, Verified ORF, "Meiosis-specific protein that down-regulates Rad51p-mediated mitotic recombination when the meiotic recombination machinery is impaired; early meiotic gene, transcribed specifically during meiotic prophase" |
| 904 | YDR016C | DAD1 SGDID:S000002423, Chr IV from 478756-478472, reverse complement, Verified ORF, "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" |
| 905 | YDR017C | KCS1 SGDID:S000002424, Chr IV from 482265-479113, reverse complement, Verified ORF, "Inositol hexakisphosphate (IP6) and inositol heptakisphosphate (IP7) kinase; generation of high energy inositol pyrophosphates by Kcs1p is required for many processes such as vacuolar biogenesis, stress response and telomere maintenance" |
| 906 | YDR018C | YDR018C SGDID:S000002425, Chr IV from 483858-482668, reverse complement, Uncharacterized ORF, "Probable membrane protein with three predicted transmembrane domains; homologous to Ybr042cp, similar to C. elegans F55A11.5 and maize 1-acyl-glycerol-3-phosphate acyltransferase; null exhibits no apparent phenotype" |
| 907 | YDR019C | GCV1 SGDID:S000002426, Chr IV from 485363-484161, reverse complement, Verified ORF, "T subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of levels of 5,10-methylene-THF in the cytoplasm" |
| 908 | YDR020C | YDR020C SGDID:S000002427, Chr IV from 486442-485744, reverse complement, Uncharacterized ORF, "Predicted protein shares weak similarity with uridine kinases and with phosphoribokinases; null mutant suppresses dst1delta sensitivity for 6-azauracil" |
| 909 | YDR021W | FAL1 SGDID:S000002428, Chr IV from 486802-488001, Verified ORF, "Nucleolar protein required for maturation of 18S rRNA, member of the eIF4A subfamily of DEAD-box ATP-dependent RNA helicases" |
| 910 | YDR022C | CIS1 SGDID:S000002429, Chr IV from 488660-488070, reverse complement, Verified ORF, "Autophagy-specific protein required for autophagosome formation; may form a complex with Atg17p and Atg29p that localizes other proteins to the pre-autophagosomal structure; high-copy suppressor of CIK1 deletion" |
| 911 | YDR023W | SES1 SGDID:S000002430, Chr IV from 489506-490894, Verified ORF, "Cytosolic seryl-tRNA synthetase, class II aminoacyl-tRNA synthetase that aminoacylates tRNA(Ser), displays tRNA-dependent amino acid recognition which enhances discrimination of the serine substrate, interacts with peroxin Pex21p" |
| 912 | YDR025W | RPS11A SGDID:S000002432, Chr IV from 491513-491557,491897-492322, Verified ORF, "Protein component of the small (40S) ribosomal subunit; identical to Rps11Bp and has similarity to E. coli S17 and rat S11 ribosomal proteins" |
| 913 | YDR026C | YDR026C SGDID:S000002433, Chr IV from 494266-492554, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; Myb-like DNA-binding protein that may bind to the Ter region of rDNA; interacts physically with Fob1p" |
| 914 | YDR027C | VPS54 SGDID:S000002434, Chr IV from 497316-494647, reverse complement, Verified ORF, "Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; potentially phosphorylated by Cdc28p" |
| 915 | YDR028C | REG1 SGDID:S000002435, Chr IV from 500877-497833, reverse complement, Verified ORF, "Regulatory subunit of type 1 protein phosphatase Glc7p, involved in negative regulation of glucose-repressible genes" |
| 916 | YDR030C | RAD28 SGDID:S000002437, Chr IV from 503271-501751, reverse complement, Verified ORF, "Protein involved in DNA repair, related to the human CSA protein that is involved in transcription-coupled repair nucleotide excision repair" |
| 917 | YDR031W | MIC14 SGDID:S000002438, Chr IV from 503496-503861, Verified ORF, "Mitochondrial intermembrane space cysteine motif protein of 14 kDa" |
| 918 | YDR032C | PST2 SGDID:S000002439, Chr IV from 504693-504097, reverse complement, Verified ORF, "Protein with similarity to members of a family of flavodoxin-like proteins; induced by oxidative stress in a Yap1p dependent manner; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 919 | YDR033W | MRH1 SGDID:S000002440, Chr IV from 508145-509107, Verified ORF, "Protein that localizes primarily to the plasma membrane, also found at the nuclear envelope; the authentic, non-tagged protein is detected in mitochondria in a phosphorylated state; has similarity to Hsp30p and Yro2p" |
| 920 | YDR034C | LYS14 SGDID:S000002441, Chr IV from 512107-509735, reverse complement, Verified ORF, "Transcriptional activator involved in regulation of genes of the lysine biosynthesis pathway; requires 2-aminoadipate semialdehyde as co-inducer" |
| 921 | YDR034C-A | YDR034C-A SGDID:S000007233, Chr IV from 520690-520514, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; contained within the solo Ty1 LTR element YDRWdelta7" |
| 922 | YDR034C-C | YDR034C-C SGDID:S000007344, Chr IV from 519354-518038, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 923 | YDR034C-D | YDR034C-D SGDID:S000007345, Chr IV from 519354-518062,518060-514041, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 924 | YDR034W-B | YDR034W-B SGDID:S000007234, Chr IV from 521312-521467, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery" |
| 925 | YDR035W | ARO3 SGDID:S000002442, Chr IV from 521814-522926, Verified ORF, "3-deoxy-D-arabino-heptulosonate-7-phosphate (DAHP) synthase, catalyzes the first step in aromatic amino acid biosynthesis and is feedback-inhibited by phenylalanine or high concentration of tyrosine or tryptophan" |
| 926 | YDR036C | EHD3 SGDID:S000002443, Chr IV from 524711-523209, reverse complement, Verified ORF, "3-hydroxyisobutyryl-CoA hydrolase, member of a family of enoyl-CoA hydratase/isomerases; non-tagged protein is detected in highly purified mitochondria in high-throughput studies; phosphorylated; mutation affects fluid-phase endocytosis" |
| 927 | YDR037W | KRS1 SGDID:S000002444, Chr IV from 525438-527213, Verified ORF, "Lysyl-tRNA synthetase; also identified as a negative regulator of general control of amino acid biosynthesis" |
| 928 | YDR038C | ENA5 SGDID:S000002445, Chr IV from 530695-527420, reverse complement, Verified ORF, "Protein with similarity to P-type ATPase sodium pumps, member of the Na+ efflux ATPase family" |
| 929 | YDR039C | ENA2 SGDID:S000002446, Chr IV from 534580-531305, reverse complement, Verified ORF, "P-type ATPase sodium pump, involved in Na+ efflux to allow salt tolerance; likely not involved in Li+ efflux" |
| 930 | YDR040C | ENA1 SGDID:S000002447, Chr IV from 538465-535190, reverse complement, Verified ORF, "P-type ATPase sodium pump, involved in Na+ and Li+ efflux to allow salt tolerance" |
| 931 | YDR041W | RSM10 SGDID:S000002448, Chr IV from 539801-540412, Verified ORF, "Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S10 ribosomal protein; essential for viability, unlike most other mitoribosomal proteins" |
| 932 | YDR042C | YDR042C SGDID:S000002449, Chr IV from 541201-540599, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; expression is increased in ssu72-ts69 mutant" |
| 933 | YDR043C | NRG1 SGDID:S000002450, Chr IV from 543368-542673, reverse complement, Verified ORF, "Transcriptional repressor that recruits the Cyc8p-Tup1p complex to promoters; mediates glucose repression and negatively regulates a variety of processes including filamentous growth and alkaline pH response" |
| 934 | YDR044W | HEM13 SGDID:S000002451, Chr IV from 546641-547627, Verified ORF, "Coproporphyrinogen III oxidase, an oxygen requiring enzyme that catalyzes the sixth step in the heme biosynthetic pathway; localizes to the mitochondrial inner membrane; transcription is repressed by oxygen and heme (via Rox1p and Hap1p)" |
| 935 | YDR045C | RPC11 SGDID:S000002452, Chr IV from 548309-547977, reverse complement, Verified ORF, "RNA polymerase III subunit C11; mediates pol III RNA cleavage activity and is important for termination of transcription; homologous to TFIIS" |
| 936 | YDR046C | BAP3 SGDID:S000002453, Chr IV from 550575-548761, reverse complement, Verified ORF, "Amino acid permease involved in the uptake of cysteine, leucine, isoleucine and valine" |
| 937 | YDR047W | HEM12 SGDID:S000002454, Chr IV from 551859-552947, Verified ORF, "Uroporphyrinogen decarboxylase, catalyzes the fifth step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus; activity inhibited by Cu2+, Zn2+, Fe2+, Fe3+ and sulfhydryl-specific reagents" |
| 938 | YDR049W | YDR049W SGDID:S000002456, Chr IV from 553253-555151, Uncharacterized ORF, "Zinc finger protein; putative transcription factor that may interact with proteins involved in histone acetylation or deacetylation; may be involved in altering acetylation on histone lysines" |
| 939 | YDR050C | TPI1 SGDID:S000002457, Chr IV from 556471-555725, reverse complement, Verified ORF, "Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availability; transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5' non-coding region" |
| 940 | YDR051C | YDR051C SGDID:S000002458, Chr IV from 558059-557055, reverse complement, Uncharacterized ORF, "Protein of unknown function; interacts with Hsp82p in two-hybrid assay; deletion confers sensitivity to Nickel" |
| 941 | YDR052C | DBF4 SGDID:S000002459, Chr IV from 560624-558510, reverse complement, Verified ORF, "Regulatory subunit of Cdc7p-Dbf4p kinase complex, required for Cdc7p kinase activity and initiation of DNA replication; phosphorylates the Mcm2-7 family of proteins; cell cycle regulated" |
| 942 | YDR054C | CDC34 SGDID:S000002461, Chr IV from 562326-561439, reverse complement, Verified ORF, "Ubiquitin-conjugating enzyme (E2) and catalytic subunit of SCF ubiquitin-protein ligase complex (together with Skp1p, Rbx1p, Cdc53p, and an F-box protein) that regulates cell cycle progression by targeting key substrates for degradation" |
| 943 | YDR055W | PST1 SGDID:S000002462, Chr IV from 563526-564860, Verified ORF, "Cell wall protein that contains a putative GPI-attachment site; secreted by regenerating protoplasts; up-regulated by activation of the cell integrity pathway, as mediated by Rlm1p; upregulated by cell wall damage via disruption of FKS1" |
| 944 | YDR056C | YDR056C SGDID:S000002463, Chr IV from 565639-565022, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic retiuculum; YDR056C is not an essential protein" |
| 945 | YDR057W | YOS9 SGDID:S000002464, Chr IV from 565926-567554, Verified ORF, "ER quality-control lectin; integral subunit of the HRD ligase; serves as a receptor for misfolded N-glycosylated proteins, participates in their targeting to ERAD; member of the OS-9 protein family" |
| 946 | YDR058C | TGL2 SGDID:S000002465, Chr IV from 568702-567722, reverse complement, Verified ORF, "Protein with lipolytic activity towards triacylglycerols and diacylglycerols when expressed in E. coli; role in yeast lipid degradation is unclear" |
| 947 | YDR059C | UBC5 SGDID:S000002466, Chr IV from 569769-569723,569632-569233, reverse complement, Verified ORF, "Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal proteins, central component of the cellular stress response; expression is heat inducible" |
| 948 | YDR060W | MAK21 SGDID:S000002467, Chr IV from 570647-573724, Verified ORF, "Constituent of 66S pre-ribosomal particles, required for large (60S) ribosomal subunit biogenesis; involved in nuclear export of pre-ribosomes; required for maintenance of dsRNA virus; homolog of human CAATT-binding protein" |
| 949 | YDR061W | YDR061W SGDID:S000002468, Chr IV from 574162-575781, Uncharacterized ORF, "Protein with similarity to ATP-binding cassette (ABC) transporter family members; lacks predicted membrane-spanning regions; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance" |
| 950 | YDR062W | LCB2 SGDID:S000002469, Chr IV from 576472-578157, Verified ORF, "Component of serine palmitoyltransferase, responsible along with Lcb1p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine" |
| 951 | YDR063W | YDR063W SGDID:S000002470, Chr IV from 578662-579111, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; null mutant is viable and displays decreased frequency of mitochondrial genome loss (petite formation)" |
| 952 | YDR064W | RPS13 SGDID:S000002471, Chr IV from 579457-579477,580017-580451, Verified ORF, "Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S15 and rat S13 ribosomal proteins" |
| 953 | YDR065W | YDR065W SGDID:S000002472, Chr IV from 580686-581783, Uncharacterized ORF, "Protein of unknown function, required for vacuolar acidification; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 954 | YDR066C | RTR2 SGDID:S000002473, Chr IV from 582497-581907, reverse complement, Uncharacterized ORF, "Protein of unknown function with high similarity to Rtr1p; exhibits genetic interactions with Rtr1p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YDR066C is not an essential gene" |
| 955 | YDR067C | YDR067C SGDID:S000002474, Chr IV from 583464-582790, reverse complement, Uncharacterized ORF, "Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts" |
| 956 | YDR068W | DOS2 SGDID:S000002475, Chr IV from 583712-584644, Verified ORF, "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 957 | YDR069C | DOA4 SGDID:S000002476, Chr IV from 587718-584938, reverse complement, Verified ORF, "Ubiquitin isopeptidase, required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins en route to the vacuole" |
| 958 | YDR070C | YDR070C SGDID:S000002477, Chr IV from 588378-588097, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 959 | YDR071C | PAA1 SGDID:S000002478, Chr IV from 589401-588826, reverse complement, Verified ORF, "Polyamine acetyltransferase; acetylates polyamines (e.g. putrescine, spermidine, spermine) and also aralkylamines (e.g. tryptamine, phenylethylamine); may be involved in transcription and/or DNA replication" |
| 960 | YDR072C | IPT1 SGDID:S000002479, Chr IV from 591343-589760, reverse complement, Verified ORF, "Inositolphosphotransferase 1, involved in synthesis of mannose-(inositol-P)2-ceramide (M(IP)2C), which is the most abundant sphingolipid in cells, mutation confers resistance to the antifungals syringomycin E and DmAMP1 in some growth media" |
| 961 | YDR073W | SNF11 SGDID:S000002480, Chr IV from 592437-592946, Verified ORF, "Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; interacts with a highly conserved 40-residue sequence of Snf2p" |
| 962 | YDR074W | TPS2 SGDID:S000002481, Chr IV from 593891-596581, Verified ORF, "Phosphatase subunit of the trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway" |
| 963 | YDR075W | PPH3 SGDID:S000002482, Chr IV from 597154-598080, Verified ORF, "Catalytic subunit of an evolutionarily conserved protein phosphatase complex containing Psy2p and the regulatory subunit Psy4p; required for cisplatin resistance; involved in activation of Gln3p" |
| 964 | YDR076W | RAD55 SGDID:S000002483, Chr IV from 598466-599686, Verified ORF, "Protein that stimulates strand exchange by stabilizing the binding of Rad51p to single-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; forms heterodimer with Rad57p" |
| 965 | YDR077W | SED1 SGDID:S000002484, Chr IV from 600791-601807, Verified ORF, "Major stress-induced structural GPI-cell wall glycoprotein in stationary-phase cells, associates with translating ribosomes, possible role in mitochondrial genome maintenance; ORF contains two distinct variable minisatellites" |
| 966 | YDR078C | SHU2 SGDID:S000002485, Chr IV from 602867-602196, reverse complement, Verified ORF, "Protein of unassigned function involved in mutation suppression, important for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation; associates with Shu1p, Psy3p, and Csm2p" |
| 967 | YDR079C-A | TFB5 SGDID:S000007603, Chr IV from 603809-603591, reverse complement, Verified ORF, "Component of the RNA polymerase II general transcription and DNA repair factor TFIIH; involved in transcription initiation and in nucleotide-excision repair; homolog of Chlamydomonas reinhardtii REX1-S protein involved in DNA repair" |
| 968 | YDR079W | PET100 SGDID:S000002486, Chr IV from 603062-603397, Verified ORF, "Chaperone that specifically facilitates the assembly of cytochrome c oxidase, integral to the mitochondrial inner membrane; interacts with a subcomplex of subunits VII, VIIa, and VIII (Cox7p, Cox9p, and Cox8p) but not with the holoenzyme" |
| 969 | YDR080W | VPS41 SGDID:S000002487, Chr IV from 604006-606984, Verified ORF, "Vacuolar membrane protein that is a subunit of the homotypic vacuole fusion and vacuole protein sorting (HOPS) complex; essential for membrane docking and fusion at the Golgi-to-endosome and endosome-to-vacuole stages of protein transport" |
| 970 | YDR081C | PDC2 SGDID:S000002488, Chr IV from 610079-607302, reverse complement, Verified ORF, "Transcription factor required for the synthesis of the glycolytic enzyme pyruvate decarboxylase, required for high level expression of both the THI and the PDC genes" |
| 971 | YDR082W | STN1 SGDID:S000002489, Chr IV from 610439-611923, Verified ORF, "Telomere end-binding and capping protein, plays a key role with Pol12p in linking telomerase action with completion of lagging strand synthesis, and in a regulatory step required for telomere capping" |
| 972 | YDR083W | RRP8 SGDID:S000002490, Chr IV from 612071-613249, Verified ORF, "Nucleolar protein involved in rRNA processing, pre-rRNA cleavage at site A2; also involved in telomere maintenance; mutation is synthetically lethal with a gar1 mutation" |
| 973 | YDR084C | TVP23 SGDID:S000002491, Chr IV from 614002-613403, reverse complement, Verified ORF, "Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 974 | YDR085C | AFR1 SGDID:S000002492, Chr IV from 616148-614286, reverse complement, Verified ORF, "Alpha-factor pheromone receptor regulator, negatively regulates pheromone receptor signaling; required for normal mating projection (shmoo) formation; required for Spa2p to recruit Mpk1p to shmoo tip during mating; interacts with Cdc12p" |
| 975 | YDR086C | SSS1 SGDID:S000002493, Chr IV from 617168-616926, reverse complement, Verified ORF, "Subunit of the Sec61p translocation complex (Sec61p-Sss1p-Sbh1p) that forms a channel for passage of secretory proteins through the endoplasmic reticulum membrane, and of the Ssh1p complex (Ssh1p-Sbh2p-Sss1p); interacts with Ost4p and Wbp1p" |
| 976 | YDR087C | RRP1 SGDID:S000002494, Chr IV from 618304-617468, reverse complement, Verified ORF, "Essential evolutionarily conserved nucleolar protein necessary for biogenesis of 60S ribosomal subunits and processing of pre-rRNAs to mature rRNAs, associated with several distinct 66S pre-ribosomal particles" |
| 977 | YDR088C | SLU7 SGDID:S000002495, Chr IV from 619643-618495, reverse complement, Verified ORF, "RNA splicing factor, required for ATP-independent portion of 2nd catalytic step of spliceosomal RNA splicing; interacts with Prp18p; contains zinc knuckle domain" |
| 978 | YDR089W | YDR089W SGDID:S000002496, Chr IV from 622110-624719, Uncharacterized ORF, "Protein of unknown function; deletion confers resistance to Nickel" |
| 979 | YDR090C | YDR090C SGDID:S000002497, Chr IV from 625996-625064, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 980 | YDR091C | RLI1 SGDID:S000002498, Chr IV from 628532-626706, reverse complement, Verified ORF, "Essential iron-sulfur protein required for ribosome biogenesis and translation initiation; facilitates binding of a multifactor complex (MFC) of translation initiation factors to the small ribosomal subunit; predicted ABC family ATPase" |
| 981 | YDR092W | UBC13 SGDID:S000002499, Chr IV from 629874-629903,630172-630603, Verified ORF, "Ubiquitin-conjugating enzyme involved in the error-free DNA postreplication repair pathway; interacts with Mms2p to assemble ubiquitin chains at the Ub Lys-63 residue; DNA damage triggers redistribution from the cytoplasm to the nucleus" |
| 982 | YDR093W | DNF2 SGDID:S000002500, Chr IV from 631280-636118, Verified ORF, "Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase" |
| 983 | YDR096W | GIS1 SGDID:S000002503, Chr IV from 637137-639821, Verified ORF, "JmjC domain-containing histone demethylase; transcription factor involved in the expression of genes during nutrient limitation; also involved in the negative regulation of DPP1 and PHR1" |
| 984 | YDR097C | MSH6 SGDID:S000002504, Chr IV from 643835-640107, reverse complement, Verified ORF, "Protein required for mismatch repair in mitosis and meiosis, forms a complex with Msh2p to repair both single-base & insertion-deletion mispairs; potentially phosphorylated by Cdc28p" |
| 985 | YDR098C | GRX3 SGDID:S000002505, Chr IV from 645033-644176, reverse complement, Verified ORF, "Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx4p and Grx5p; protects cells from oxidative damage" |
| 986 | YDR098C-A | YDR098C-A SGDID:S000007390, Chr IV from 651124-649802, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 987 | YDR098C-B | YDR098C-B SGDID:S000007391, Chr IV from 651124-649820,649818-645856, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 988 | YDR099W | BMH2 SGDID:S000002506, Chr IV from 653605-654426, Verified ORF, "14-3-3 protein, minor isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling" |
| 989 | YDR100W | TVP15 SGDID:S000002507, Chr IV from 655011-655442, Verified ORF, "Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p" |
| 990 | YDR101C | ARX1 SGDID:S000002508, Chr IV from 657465-655684, reverse complement, Verified ORF, "Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit biogenesis; interacts directly with Alb1; responsible for Tif6 recycling defects in absence of Rei1; associated with the ribosomal export complex" |
| 991 | YDR103W | STE5 SGDID:S000002510, Chr IV from 658348-661101, Verified ORF, "Pheromone-response scaffold protein; binds kinases Ste11p, Ste7p, and Fus3p to form a MAPK cascade complex that interacts with the plasma membrane, via a PH (pleckstrin homology) and PM/NLS domain, and with Ste4p-Ste18p, during signaling" |
| 992 | YDR104C | SPO71 SGDID:S000002511, Chr IV from 664908-661171, reverse complement, Verified ORF, "Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis" |
| 993 | YDR105C | TMS1 SGDID:S000002512, Chr IV from 666768-665347, reverse complement, Verified ORF, "Vacuolar membrane protein of unknown function that is conserved in mammals; predicted to contain eleven transmembrane helices; interacts with Pdr5p, a protein involved in multidrug resistance" |
| 994 | YDR106W | ARP10 SGDID:S000002513, Chr IV from 667002-667856, Verified ORF, "Component of the dynactin complex, localized to the pointed end of the Arp1p filament; may regulate membrane association of the complex" |
| 995 | YDR107C | TMN2 SGDID:S000002514, Chr IV from 671032-669014, reverse complement, Verified ORF, "Protein with a role in cellular adhesion and filamentous growth; similar to Emp70p and Tmn3p; member of the evolutionarily conserved Transmembrane Nine family of proteins with nine membrane-spanning segments" |
| 996 | YDR108W | GSG1 SGDID:S000002515, Chr IV from 671267-673363, Verified ORF, "Subunit of TRAPP (transport protein particle), a multi-subunit complex involved in targeting and/or fusion of ER-to-Golgi transport vesicles with their acceptor compartment; protein has late meiotic role, following DNA replication" |
| 997 | YDR109C | YDR109C SGDID:S000002516, Chr IV from 675665-673518, reverse complement, Uncharacterized ORF, "Putative kinase" |
| 998 | YDR110W | FOB1 SGDID:S000002517, Chr IV from 676100-677800, Verified ORF, "Nucleolar protein required for DNA replication fork blocking and recombinational hotspot activities; binds to the replication fork barrier site in the rDNA region; related to retroviral integrases" |
| 999 | YDR111C | ALT2 SGDID:S000002518, Chr IV from 679762-678239, reverse complement, Uncharacterized ORF, "Putative alanine transaminase (glutamic pyruvic transaminase)" |
| 1000 | YDR113C | PDS1 SGDID:S000002520, Chr IV from 681615-680494, reverse complement, Verified ORF, "Securin that inhibits anaphase by binding separin Esp1p, also blocks cyclin destruction and mitotic exit, essential for cell cycle arrest in mitosis in the presence of DNA damage or aberrant mitotic spindles; also present in meiotic nuclei" |
| 1001 | YDR114C | YDR114C SGDID:S000002521, Chr IV from 682224-681922, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; deletion mutant exhibits poor growth at elevated pH and calcium" |
| 1002 | YDR115W | YDR115W SGDID:S000002522, Chr IV from 682173-682490, Uncharacterized ORF, "Putative mitochondrial ribosomal protein of the large subunit, has similarity to E. coli L34 ribosomal protein; required for respiratory growth, as are most mitochondrial ribosomal proteins" |
| 1003 | YDR116C | MRPL1 SGDID:S000002523, Chr IV from 683579-682722, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 1004 | YDR117C | TMA64 SGDID:S000002524, Chr IV from 685641-683944, reverse complement, Verified ORF, "Protein of unknown function that associates with ribosomes; has a putative RNA binding domain" |
| 1005 | YDR118W | APC4 SGDID:S000002525, Chr IV from 685880-687838, Verified ORF, "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" |
| 1006 | YDR119W | VBA4 SGDID:S000002526, Chr IV from 688225-690531, Uncharacterized ORF, "Protein of unknown function with proposed role as a basic amino acid permease based on phylogeny; GFP-fusion protein localizes to vacuolar membrane; physical interaction with Atg27p suggests a possible role in autophagy; non-essential gene" |
| 1007 | YDR119W-A | YDR119W-A SGDID:S000113555, Chr IV from 691012-691212, Uncharacterized ORF, "Putative protein of unknown function" |
| 1008 | YDR120C | TRM1 SGDID:S000002527, Chr IV from 693259-691547, reverse complement, Verified ORF, "tRNA methyltransferase, localizes to both the nucleus and mitochondrion to produce the modified base N2,N2-dimethylguanosine in tRNAs in both compartments" |
| 1009 | YDR121W | DPB4 SGDID:S000002528, Chr IV from 693583-694173, Verified ORF, "Shared subunit of DNA polymerase (II) epsilon and of ISW2/yCHRAC chromatin accessibility complex; involved in both chromosomal DNA replication and in inheritance of telomeric silencing" |
| 1010 | YDR122W | KIN1 SGDID:S000002529, Chr IV from 694698-697892, Verified ORF, "Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin2p" |
| 1011 | YDR123C | INO2 SGDID:S000002530, Chr IV from 699466-698552, reverse complement, Verified ORF, "Component of the heteromeric Ino2p/Ino4p basic helix-loop-helix transcription activator that binds inositol/choline-responsive elements (ICREs), required for derepression of phospholipid biosynthetic genes in response to inositol depletion" |
| 1012 | YDR124W | YDR124W SGDID:S000002531, Chr IV from 700313-701287, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene; expression is strongly induced by alpha factor" |
| 1013 | YDR125C | ECM18 SGDID:S000002532, Chr IV from 702756-701395, reverse complement, Verified ORF, "Protein of unknown function, similar to Rlp24p" |
| 1014 | YDR126W | SWF1 SGDID:S000002533, Chr IV from 703232-704242, Verified ORF, "Palmitoyltransferase that acts on the SNAREs Snc1p, Syn8p, Tlg1p and likely on all SNAREs; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; may have a role in vacuole fusion" |
| 1015 | YDR127W | ARO1 SGDID:S000002534, Chr IV from 704482-709248, Verified ORF, "Pentafunctional arom protein, catalyzes steps 2 through 6 in the biosynthesis of chorismate, which is a precursor to aromatic amino acids" |
| 1016 | YDR128W | YDR128W SGDID:S000002535, Chr IV from 709547-712993, Uncharacterized ORF, "Putative protein of unknown function; YDR128W is synthetically sick with cdc13-1" |
| 1017 | YDR129C | SAC6 SGDID:S000002536, Chr IV from 715377-715357,715245-713338, reverse complement, Verified ORF, "Fimbrin, actin-bundling protein; cooperates with Scp1p (calponin/transgelin) in the organization and maintenance of the actin cytoskeleton" |
| 1018 | YDR130C | FIN1 SGDID:S000002537, Chr IV from 716620-715745, reverse complement, Verified ORF, "Spindle pole body-related intermediate filament protein, forms cell cycle-specific filaments between spindle pole bodies in mother and daughter cells, able to self-assemble, expression induced during S/G2, localization cell-cycle dependent" |
| 1019 | YDR131C | YDR131C SGDID:S000002538, Chr IV from 718458-716788, reverse complement, Uncharacterized ORF, "F-box protein, substrate-specific adaptor subunit that recruits substrates to a core ubiquitination complex" |
| 1020 | YDR132C | YDR132C SGDID:S000002539, Chr IV from 720301-718814, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1021 | YDR135C | YCF1 SGDID:S000002542, Chr IV from 727549-723002, reverse complement, Verified ORF, "Vacuolar glutathione S-conjugate transporter of the ATP-binding cassette family, has a role in detoxifying metals such as cadmium, mercury, and arsenite; also transports unconjugated bilirubin; similar to human cystic fibrosis protein CFTR" |
| 1022 | YDR137W | RGP1 SGDID:S000002544, Chr IV from 728257-730248, Verified ORF, "Subunit of a Golgi membrane exchange factor (Ric1p-Rgp1p) that catalyzes nucleotide exchange on Ypt6p" |
| 1023 | YDR138W | HPR1 SGDID:S000002545, Chr IV from 730576-732834, Verified ORF, "Subunit of THO/TREX complexes that couple transcription elongation with mitotic recombination and with mRNA metabolism and export, subunit of an RNA Pol II complex; regulates lifespan; involved in telomere maintenance; similar to Top1p" |
| 1024 | YDR139C | RUB1 SGDID:S000002546, Chr IV from 733922-733774,733700-733616, reverse complement, Verified ORF, "Ubiquitin-like protein with similarity to mammalian NEDD8; conjugation (neddylation) substrates include the cullins Cdc53p, Rtt101p, and Cul3p; activated by Ula1p and Uba3p (E1 enzyme pair); conjugation mediated by Ubc12p (E2 enzyme)" |
| 1025 | YDR140W | MTQ2 SGDID:S000002547, Chr IV from 734136-734801, Verified ORF, "S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; methylates release factor eRF1 (Sup45p) in vitro; is not an essential gene; similar to E.coli PrmC" |
| 1026 | YDR141C | DOP1 SGDID:S000002548, Chr IV from 739995-734899, reverse complement, Verified ORF, "Protein of unknown function, essential for viability, involved in establishing cellular polarity and morphogenesis; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 1027 | YDR142C | PEX7 SGDID:S000002549, Chr IV from 741598-740471, reverse complement, Verified ORF, "Peroxisomal signal receptor for the N-terminal nonapeptide signal (PTS2) of peroxisomal matrix proteins; WD repeat protein; defects in human homolog cause lethal rhizomelic chondrodysplasia punctata (RCDP)" |
| 1028 | YDR143C | SAN1 SGDID:S000002550, Chr IV from 743872-742040, reverse complement, Verified ORF, "Ubiquitin-protein ligase, involved in the proteasome-dependent degradation of aberrant nuclear proteins" |
| 1029 | YDR144C | MKC7 SGDID:S000002551, Chr IV from 746099-744309, reverse complement, Verified ORF, "GPI-anchored aspartyl protease (yapsin) involved in protein processing; shares functions with Yap3p and Kex2p" |
| 1030 | YDR145W | TAF12 SGDID:S000002552, Chr IV from 746736-748355, Verified ORF, "Subunit (61/68 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A" |
| 1031 | YDR146C | SWI5 SGDID:S000002553, Chr IV from 750740-748611, reverse complement, Verified ORF, "Transcription factor that activates transcription of genes expressed at the M/G1 phase boundary and in G1 phase; localization to the nucleus occurs during G1 and appears to be regulated by phosphorylation by Cdc28p kinase" |
| 1032 | YDR147W | EKI1 SGDID:S000002554, Chr IV from 751629-753233, Verified ORF, "Ethanolamine kinase, primarily responsible for phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway; exhibits some choline kinase activity, thus contributing to phosphatidylcholine synthesis via the CDP-choline pathway" |
| 1033 | YDR148C | KGD2 SGDID:S000002555, Chr IV from 755064-753673, reverse complement, Verified ORF, "Dihydrolipoyl transsuccinylase, component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes the oxidative decarboxylation of alpha-ketoglutarate to succinyl-CoA in the TCA cycle; phosphorylated" |
| 1034 | YDR150W | NUM1 SGDID:S000002557, Chr IV from 755626-763872, Verified ORF, "Protein required for nuclear migration, localizes to the mother cell cortex and the bud tip; may mediate interactions of dynein and cytoplasmic microtubules with the cell cortex" |
| 1035 | YDR151C | CTH1 SGDID:S000002558, Chr IV from 765153-764176, reverse complement, Verified ORF, "Member of the CCCH zinc finger family; has similarity to mammalian Tis11 protein, which activates transcription and also has a role in mRNA degradation; may function with Tis11p in iron homeostasis" |
| 1036 | YDR152W | GIR2 SGDID:S000002559, Chr IV from 765704-766501, Verified ORF, "Highly-acidic cytoplasmic RWD domain-containing protein of unknown function, sensitive to proteolysis, N-terminal region has high content of acidic amino acid residues, putative IUP (intrinsically unstructured protein)" |
| 1037 | YDR153C | ENT5 SGDID:S000002560, Chr IV from 767969-766734, reverse complement, Verified ORF, "Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p, clathrin adaptor complex AP-1, and clathrin" |
| 1038 | YDR155C | CPR1 SGDID:S000002562, Chr IV from 768998-768510, reverse complement, Verified ORF, "Cytoplasmic peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds the drug cyclosporin A" |
| 1039 | YDR156W | RPA14 SGDID:S000002563, Chr IV from 769523-769936, Verified ORF, "RNA polymerase I subunit A14" |
| 1040 | YDR158W | HOM2 SGDID:S000002565, Chr IV from 770355-771452, Verified ORF, "Aspartic beta semi-aldehyde dehydrogenase, catalyzes the second step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis" |
| 1041 | YDR159W | SAC3 SGDID:S000002566, Chr IV from 771875-775780, Verified ORF, "Nuclear pore-associated protein, forms a complex with Thp1p that is involved in transcription and in mRNA export from the nucleus" |
| 1042 | YDR160W | SSY1 SGDID:S000002567, Chr IV from 776161-778719, Verified ORF, "Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes" |
| 1043 | YDR161W | YDR161W SGDID:S000002568, Chr IV from 779041-780204, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene; proposed function in rRNA and ribosome biosynthesis based on transcriptional co-regulation" |
| 1044 | YDR162C | NBP2 SGDID:S000002569, Chr IV from 781098-780388, reverse complement, Verified ORF, "Protein involved in the HOG (high osmolarity glycerol) pathway, negatively regulates Hog1p by recruitment of phosphatase Ptc1p the Pbs2p-Hog1p complex, found in the nucleus and cytoplasm, contains an SH3 domain that binds Pbs2p" |
| 1045 | YDR163W | CWC15 SGDID:S000002570, Chr IV from 781421-781948, Verified ORF, "Non-essential protein involved in pre-mRNA splicing, component of a complex containing Cef1p; has similarity to S. pombe Cwf15p" |
| 1046 | YDR164C | SEC1 SGDID:S000002571, Chr IV from 784213-782039, reverse complement, Verified ORF, "Sm-like protein involved in docking and fusion of exocytic vesicles through binding to assembled SNARE complexes at the membrane; localization to sites of secretion (bud neck and bud tip) is dependent on SNARE function" |
| 1047 | YDR165W | TRM82 SGDID:S000002572, Chr IV from 784869-786203, Verified ORF, "Subunit of a tRNA methyltransferase complex composed of Trm8p and Trm82p that catalyzes 7-methylguanosine modification of tRNA" |
| 1048 | YDR166C | SEC5 SGDID:S000002573, Chr IV from 789219-786304, reverse complement, Verified ORF, "Essential 107kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis" |
| 1049 | YDR167W | TAF10 SGDID:S000002574, Chr IV from 789447-790067, Verified ORF, "Subunit (145 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification" |
| 1050 | YDR168W | CDC37 SGDID:S000002575, Chr IV from 790326-791846, Verified ORF, "Essential Hsp90p co-chaperone; necessary for passage through the START phase of the cell cycle; stabilizes protein kinase nascent chains and participates along with Hsp90p in their folding" |
| 1051 | YDR169C | STB3 SGDID:S000002576, Chr IV from 793887-792346, reverse complement, Verified ORF, "Protein that binds Sin3p in a two-hybrid assay" |
| 1052 | YDR169C-A | YDR169C-A SGDID:S000028538, Chr IV from 794721-794572, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 1053 | YDR170C | SEC7 SGDID:S000002577, Chr IV from 802220-796191, reverse complement, Verified ORF, "Guanine nucleotide exchange factor (GEF) for ADP ribosylation factors involved in proliferation of the Golgi, intra-Golgi transport and ER-to-Golgi transport; found in the cytoplasm and on Golgi-associated coated vesicles" |
| 1054 | YDR170W-A | YDR170W-A SGDID:S000007227, Chr IV from 803193-804515, transposable_element_gene, "Retrotransposon TYA Gag gene; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag; YDR170W-A is part of a mutant retrotransposon" |
| 1055 | YDR171W | HSP42 SGDID:S000002578, Chr IV from 806619-807746, Verified ORF, "Small heat shock protein (sHSP) with chaperone activity; forms barrel-shaped oligomers that suppress unfolded protein aggregation; involved in cytoskeleton reorganization after heat shock" |
| 1056 | YDR172W | SUP35 SGDID:S000002579, Chr IV from 808322-810379, Verified ORF, "Translation termination factor eRF3; altered protein conformation creates the [PSI(+)] prion, a dominant cytoplasmically inherited protein aggregate that alters translational fidelity and creates a nonsense suppressor phenotype" |
| 1057 | YDR173C | ARG82 SGDID:S000002580, Chr IV from 811630-810563, reverse complement, Verified ORF, "Inositol polyphosphate multikinase (IPMK), sequentially phosphorylates Ins(1,4,5)P3 to form Ins(1,3,4,5,6)P5; also has diphosphoinositol polyphosphate synthase activity; regulates arginine-, phosphate-, and nitrogen-responsive genes" |
| 1058 | YDR174W | HMO1 SGDID:S000002581, Chr IV from 812108-812848, Verified ORF, "Chromatin associated high mobility group (HMG) family member involved in genome maintenance; rDNA-binding component of the Pol I transcription system; associates with a 5'-3' DNA helicase and Fpr1p, a prolyl isomerase" |
| 1059 | YDR175C | RSM24 SGDID:S000002582, Chr IV from 814150-813191, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 1060 | YDR176W | NGG1 SGDID:S000002583, Chr IV from 814450-816558, Verified ORF, "Transcriptional regulator involved in glucose repression of Gal4p-regulated genes; component of transcriptional adaptor and histone acetyltransferase complexes, the ADA complex, the SAGA complex, and the SLIK complex" |
| 1061 | YDR177W | UBC1 SGDID:S000002584, Chr IV from 816876-817523, Verified ORF, "Ubiquitin-conjugating enzyme that mediates selective degradation of short-lived and abnormal proteins; plays a role in vesicle biogenesis and ER-associated protein degradation (ERAD); component of the cellular stress response" |
| 1062 | YDR178W | SDH4 SGDID:S000002585, Chr IV from 817948-818493, Verified ORF, "Membrane anchor subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone" |
| 1063 | YDR179C | CSN9 SGDID:S000002586, Chr IV from 819194-818706, reverse complement, Verified ORF, "Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling" |
| 1064 | YDR179W-A | YDR179W-A SGDID:S000002587, Chr IV from 819431-820822, Uncharacterized ORF, "Putative protein of unknown function" |
| 1065 | YDR180W | SCC2 SGDID:S000002588, Chr IV from 821293-825774, Verified ORF, "Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during DSB repair via histone H2AX; evolutionarily-conserved adherin" |
| 1066 | YDR181C | SAS4 SGDID:S000002589, Chr IV from 827353-825908, reverse complement, Verified ORF, "Subunit of the SAS complex (Sas2p, Sas4p, Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; required for the HAT activity of Sas2p" |
| 1067 | YDR182W | CDC1 SGDID:S000002590, Chr IV from 827580-829055, Verified ORF, "Putative membrane protein of unknown function involved in Mn2+ homeostasis; mutants display actin and general growth defects, heterogeneous cell cycle arrests, and pleiotropic defects in cell cycle progression and organelle distribution" |
| 1068 | YDR182W-A | YDR182W-A SGDID:S000028539, Chr IV from 829149-829352, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 1069 | YDR183W | PLP1 SGDID:S000002591, Chr IV from 829583-830275, Verified ORF, "Protein with a possible role in folding of beta-tubulin; has weak similarity to phosducins, which are G-protein regulators" |
| 1070 | YDR184C | ATC1 SGDID:S000002592, Chr IV from 831511-830627, reverse complement, Verified ORF, "Nuclear protein, possibly involved in regulation of cation stress responses and/or in the establishment of bipolar budding pattern" |
| 1071 | YDR185C | YDR185C SGDID:S000002593, Chr IV from 832471-831932, reverse complement, Uncharacterized ORF, "Mitochondrial protein of unknown function; has similarity to Ups1p, which is involved in regulation of alternative topogenesis of the dynamin-related GTPase Mgm1p" |
| 1072 | YDR186C | YDR186C SGDID:S000002594, Chr IV from 835490-832857, reverse complement, Verified ORF, "Putative protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 1073 | YDR188W | CCT6 SGDID:S000002596, Chr IV from 836419-838059, Verified ORF, "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, essential protein that is required for the assembly of actin and tubulins in vivo; contains an ATP-binding motif" |
| 1074 | YDR189W | SLY1 SGDID:S000002597, Chr IV from 838390-840390, Verified ORF, "Hydrophilic protein involved in vesicle trafficking between the ER and Golgi; SM (Sec1/Munc-18) family protein that binds the tSNARE Sed5p and stimulates its assembly into a trans-SNARE membrane-protein complex" |
| 1075 | YDR190C | RVB1 SGDID:S000002598, Chr IV from 841993-840602, reverse complement, Verified ORF, "Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; member of the RUVB-like protein family" |
| 1076 | YDR191W | HST4 SGDID:S000002599, Chr IV from 842335-843447, Verified ORF, "Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism" |
| 1077 | YDR192C | NUP42 SGDID:S000002600, Chr IV from 844859-843567, reverse complement, Verified ORF, "Subunit of the nuclear pore complex (NPC) that localizes exclusively to the cytoplasmic side; involved in RNA export, most likely at a terminal step; interacts with Gle1p" |
| 1078 | YDR194C | MSS116 SGDID:S000002602, Chr IV from 847944-845950, reverse complement, Verified ORF, "DEAD-box protein required for efficient splicing of mitochondrial Group I and II introns; non-polar RNA helicase that also facilities strand annealing" |
| 1079 | YDR194W-A | YDR194W-A SGDID:S000028541, Chr IV from 848069-848221, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 1080 | YDR195W | REF2 SGDID:S000002603, Chr IV from 848597-850198, Verified ORF, "RNA-binding protein involved in the cleavage step of mRNA 3'-end formation prior to polyadenylation, and in snoRNA maturation; part of holo-CPF subcomplex APT, which associates with 3'-ends of snoRNA- and mRNA-encoding genes" |
| 1081 | YDR196C | YDR196C SGDID:S000002604, Chr IV from 850997-850272, reverse complement, Uncharacterized ORF, "Putative dephospho-CoA kinase (DPCK) that catalyzes the final step in Coenzyme A biosynthesis; essential for viability; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 1082 | YDR197W | CBS2 SGDID:S000002605, Chr IV from 851226-852395, Verified ORF, "Mitochondrial translational activator of the COB mRNA; interacts with translating ribosomes, acts on the COB mRNA 5'-untranslated leader" |
| 1083 | YDR198C | RKM2 SGDID:S000002606, Chr IV from 853970-852531, reverse complement, Verified ORF, "Ribosomal protein lysine methyltransferase, responsible for epsilon-trimethylation of the lysine residue at position 10 of Rpl12Ap and Rpl12Bp" |
| 1084 | YDR200C | VPS64 SGDID:S000002608, Chr IV from 856091-854277, reverse complement, Verified ORF, "Cytoplasmic protein required for cytoplasm to vacuole targeting of proteins; forms a complex with Far3p, Far7p, Far10p, and Far11p that is involved in pheromone-induced cell cycle arrest; also localized to the endoplasmic reticulum membrane" |
| 1085 | YDR201W | SPC19 SGDID:S000002609, Chr IV from 856315-856812, Verified ORF, "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; also localized to nuclear side of spindle pole body" |
| 1086 | YDR202C | RAV2 SGDID:S000002610, Chr IV from 857951-856896, reverse complement, Verified ORF, "Subunit of RAVE (Rav1p, Rav2p, Skp1p), a complex that associates with the V1 domain of the vacuolar membrane (H+)-ATPase (V-ATPase) and promotes assembly and reassembly of the holoenzyme" |
| 1087 | YDR204W | COQ4 SGDID:S000002612, Chr IV from 858135-859142, Verified ORF, "Protein with a role in ubiquinone (Coenzyme Q) biosynthesis, possibly functioning in stabilization of Coq7p; located on the matrix face of the mitochondrial inner membrane; component of a mitochondrial ubiquinone-synthesizing complex" |
| 1088 | YDR205W | MSC2 SGDID:S000002613, Chr IV from 859344-861518, Verified ORF, "Member of the cation diffusion facilitator family, localizes to the endoplasmic reticulum and nucleus; mutations affect the cellular distribution of zinc and also confer defects in meiotic recombination between homologous chromatids" |
| 1089 | YDR206W | EBS1 SGDID:S000002614, Chr IV from 862052-864706, Verified ORF, "Protein involved in inhibition of translation and nonsense-mediated decay; interacts with cap binding protein Cdc33p and with Nam7p; localizes to P-bodies upon glucose starvation; mRNA abundance regulated by mRNA decay factors" |
| 1090 | YDR207C | UME6 SGDID:S000002615, Chr IV from 867520-865010, reverse complement, Verified ORF, "Key transcriptional regulator of early meiotic genes, binds URS1 upstream regulatory sequence, couples metabolic responses to nutritional cues with initiation and progression of meiosis, forms complex with Ime1p, and also with Sin3p-Rpd3p" |
| 1091 | YDR208W | MSS4 SGDID:S000002616, Chr IV from 868222-870561, Verified ORF, "Phosphatidylinositol-4-phosphate 5-kinase, involved in actin cytoskeleton organization and cell morphogenesis; multicopy suppressor of stt4 mutation" |
| 1092 | YDR210C-C | YDR210C-C SGDID:S000007409, Chr IV from 883925-882603, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 1093 | YDR210C-D | YDR210C-D SGDID:S000007410, Chr IV from 883925-882621,882619-878657, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 1094 | YDR210W | YDR210W SGDID:S000002618, Chr IV from 871072-871299, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery" |
| 1095 | YDR210W-A | YDR210W-A SGDID:S000007392, Chr IV from 872110-873426, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 1096 | YDR210W-B | YDR210W-B SGDID:S000007393, Chr IV from 872110-873402,873404-877423, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 1097 | YDR211W | GCD6 SGDID:S000002619, Chr IV from 884725-886863, Verified ORF, "Catalytic epsilon subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression" |
| 1098 | YDR212W | TCP1 SGDID:S000002620, Chr IV from 887230-888909, Verified ORF, "Alpha subunit of chaperonin-containing T-complex, which mediates protein folding in the cytosol; involved in maintenance of actin cytoskeleton; homolog to Drosophila melanogaster and mouse tailless complex polypeptide" |
| 1099 | YDR213W | UPC2 SGDID:S000002621, Chr IV from 889749-892490, Verified ORF, "Sterol regulatory element binding protein, induces transcription of sterol transport and biosynthetic genes; involved in the anaerobic induction of DAN/TIR mannoproteins and seripauperins; binucleate zinc cluster protein; Ecm22p homolog" |
| 1100 | YDR214W | AHA1 SGDID:S000002622, Chr IV from 892873-893925, Verified ORF, "Co-chaperone that binds to Hsp82p and activates its ATPase activity; similar to Hch1p; expression is regulated by stresses such as heat shock" |
| 1101 | YDR216W | ADR1 SGDID:S000002624, Chr IV from 895032-899003, Verified ORF, "Carbon source-responsive zinc-finger transcription factor, required for transcription of the glucose-repressed gene ADH2, of peroxisomal protein genes, and of genes required for ethanol, glycerol, and fatty acid utilization" |
| 1102 | YDR217C | RAD9 SGDID:S000002625, Chr IV from 903477-899548, reverse complement, Verified ORF, "DNA damage-dependent checkpoint protein, required for cell-cycle arrest in G1/S, intra-S, and G2/M; transmits checkpoint signal by activating Rad53p and Chk1p; hyperphosphorylated by Mec1p and Tel1p; potential Cdc28p substrate" |
| 1103 | YDR218C | SPR28 SGDID:S000002626, Chr IV from 905049-903778, reverse complement, Verified ORF, "Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes; meiotic septin expressed at high levels during meiotic divisions and ascospore formation" |
| 1104 | YDR219C | MFB1 SGDID:S000002627, Chr IV from 906849-905452, reverse complement, Verified ORF, "Mitochondria-associated F-box protein involved in maintenance of normal mitochondrial morphology; interacts with Skp1p through the F-box motif; preferentially localizes to the mother cell during budding" |
| 1105 | YDR221W | GTB1 SGDID:S000002629, Chr IV from 907327-909435, Verified ORF, "Glucosidase II beta subunit, forms a complex with alpha subunit Rot2p, involved in removal of two glucose residues from N-linked glycans during glycoprotein biogenesis in the ER" |
| 1106 | YDR222W | YDR222W SGDID:S000002630, Chr IV from 910051-911298, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 1107 | YDR223W | CRF1 SGDID:S000002631, Chr IV from 912096-913499, Verified ORF, "Transcriptional corepressor involved in the regulation of ribosomal protein gene transcription via the TOR signaling pathway and protein kinase A, phosphorylated by activated Yak1p which promotes accumulation of Crf1p in the nucleus" |
| 1108 | YDR224C | HTB1 SGDID:S000002632, Chr IV from 914709-914314, reverse complement, Verified ORF, "One of two nearly identical (see HTB2) histone H2B subtypes required for chromatin assembly and chromosome function; Rad6p-Bre1p-Lge1p mediated ubiquitination regulates transcriptional activation, meiotic DSB formation and H3 methylation" |
| 1109 | YDR225W | HTA1 SGDID:S000002633, Chr IV from 915527-915925, Verified ORF, "One of two nearly identical (see also HTA2) histone H2A subtypes; core histone required for chromatin assembly and chromosome function; DNA damage-dependent phosphorylation by Mec1p facilitates DNA repair; acetylated by Nat4p" |
| 1110 | YDR226W | ADK1 SGDID:S000002634, Chr IV from 916483-917151, Verified ORF, "Adenylate kinase, required for purine metabolism; localized to the cytoplasm and the mitochondria; lacks cleavable signal sequence" |
| 1111 | YDR227W | SIR4 SGDID:S000002635, Chr IV from 917568-921644, Verified ORF, "Silent information regulator that, together with SIR2 and SIR3, is involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci; potentially phosphorylated by Cdc28p; some alleles of SIR4 prolong lifespan" |
| 1112 | YDR228C | PCF11 SGDID:S000002636, Chr IV from 923803-921923, reverse complement, Verified ORF, "mRNA 3' end processing factor, essential component of cleavage and polyadenylation factor IA (CF IA), involved in pre-mRNA 3' end processing and in transcription termination; binds C-terminal domain of largest subunit of RNA pol II (Rpo21p)" |
| 1113 | YDR229W | IVY1 SGDID:S000002637, Chr IV from 924782-926143, Verified ORF, "Phospholipid-binding protein that interacts with both Ypt7p and Vps33p, may partially counteract the action of Vps33p and vice versa, localizes to the rim of the vacuole as cells approach stationary phase" |
| 1114 | YDR231C | COX20 SGDID:S000002639, Chr IV from 926907-926290, reverse complement, Verified ORF, "Mitochondrial inner membrane protein, required for proteolytic processing of Cox2p and its assembly into cytochrome c oxidase" |
| 1115 | YDR232W | HEM1 SGDID:S000002640, Chr IV from 927449-929095, Verified ORF, "5-aminolevulinate synthase, catalyzes the first step in the heme biosynthetic pathway; an N-terminal signal sequence is required for localization to the mitochondrial matrix; expression is regulated by Hap2p-Hap3p" |
| 1116 | YDR233C | RTN1 SGDID:S000002641, Chr IV from 930354-929467, reverse complement, Verified ORF, "ER membrane protein that interacts with exocyst subunit Sec6p and with Yip3p; also interacts with Sbh1p; null mutant has an altered (mostly cisternal) ER morphology; member of the RTNLA (reticulon-like A) subfamily" |
| 1117 | YDR234W | LYS4 SGDID:S000002642, Chr IV from 931126-933207, Verified ORF, "Homoaconitase, catalyzes the conversion of homocitrate to homoisocitrate, which is a step in the lysine biosynthesis pathway" |
| 1118 | YDR235W | PRP42 SGDID:S000002643, Chr IV from 933501-935135, Verified ORF, "U1 snRNP protein involved in splicing, required for U1 snRNP biogenesis; contains multiple tetriatricopeptide repeats" |
| 1119 | YDR236C | FMN1 SGDID:S000002644, Chr IV from 935889-935233, reverse complement, Verified ORF, "Riboflavin kinase, phosphorylates riboflavin to form riboflavin monophosphate (FMN), which is a necessary cofactor for many enzymes; localizes to microsomes and to the mitochondrial inner membrane" |
| 1120 | YDR237W | MRPL7 SGDID:S000002645, Chr IV from 936612-937490, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 1121 | YDR238C | SEC26 SGDID:S000002646, Chr IV from 940813-937892, reverse complement, Verified ORF, "Essential beta-coat protein of the COPI coatomer, involved in ER-to-Golgi protein trafficking and maintenance of normal ER morphology; shares 43% sequence identity with mammalian beta-coat protein (beta-COP)" |
| 1122 | YDR239C | YDR239C SGDID:S000002647, Chr IV from 943417-941054, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments" |
| 1123 | YDR240C | SNU56 SGDID:S000002648, Chr IV from 945149-943671, reverse complement, Verified ORF, "Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart; interacts with mRNA in commitment complex" |
| 1124 | YDR242W | AMD2 SGDID:S000002650, Chr IV from 946804-948453, Verified ORF, "Putative amidase" |
| 1125 | YDR243C | PRP28 SGDID:S000002651, Chr IV from 950281-948515, reverse complement, Verified ORF, "RNA helicase in the DEAD-box family, involved in RNA isomerization at the 5' splice site" |
| 1126 | YDR244W | PEX5 SGDID:S000002652, Chr IV from 950560-952398, Verified ORF, "Peroxisomal membrane signal receptor for the C-terminal tripeptide signal sequence (PTS1) of peroxisomal matrix proteins, required for peroxisomal matrix protein import; also proposed to have PTS1-receptor independent functions" |
| 1127 | YDR245W | MNN10 SGDID:S000002653, Chr IV from 952797-953978, Verified ORF, "Subunit of a Golgi mannosyltransferase complex also containing Anp1p, Mnn9p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; membrane protein of the mannosyltransferase family" |
| 1128 | YDR246W | TRS23 SGDID:S000002654, Chr IV from 954285-954944, Verified ORF, "One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic; human homolog is TRAPPC4" |
| 1129 | YDR246W-A | YDR246W-A SGDID:S000028542, Chr IV from 955130-955330, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 1130 | YDR247W | VHS1 SGDID:S000002655, Chr IV from 956010-957395, Verified ORF, "Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; homolog of Sks1p" |
| 1131 | YDR248C | YDR248C SGDID:S000002656, Chr IV from 958336-957755, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 1132 | YDR249C | YDR249C SGDID:S000002657, Chr IV from 959799-958678, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1133 | YDR251W | PAM1 SGDID:S000002659, Chr IV from 960611-963103, Verified ORF, "Essential protein of unknown function; exhibits variable expression during colony morphogenesis; overexpression permits survival without protein phosphatase 2A, inhibits growth, and induces a filamentous phenotype" |
| 1134 | YDR252W | BTT1 SGDID:S000002660, Chr IV from 963409-963858, Verified ORF, "Beta3 subunit of the heterotrimeric nascent polypeptide-associated complex which binds ribosomes via its beta-subunits in close proximity to nascent polypeptides; interacts with Caf130p of the CCR4-NOT complex; similar to human BTF3" |
| 1135 | YDR253C | MET32 SGDID:S000002661, Chr IV from 964562-963987, reverse complement, Verified ORF, "Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met31p" |
| 1136 | YDR254W | CHL4 SGDID:S000002662, Chr IV from 965110-966486, Verified ORF, "Outer kinetochore protein required for chromosome stability, interacts with kinetochore proteins Ctf19p, Ctf3p, and Iml3p; exhibits a two-hybrid interaction with Mif2p; association with CEN DNA requires Ctf19p" |
| 1137 | YDR255C | RMD5 SGDID:S000002663, Chr IV from 967819-966554, reverse complement, Verified ORF, "Cytosolic protein required for sporulation; also required for the ubiquitination of the gluconeogenetic enzyme fructose-1,6-bisphosphatase, which is degraded rapidly after the switch from gluconeogenesis to glycolysis" |
| 1138 | YDR256C | CTA1 SGDID:S000002664, Chr IV from 969677-968130, reverse complement, Verified ORF, "Catalase A, breaks down hydrogen peroxide in the peroxisomal matrix formed by acyl-CoA oxidase (Pox1p) during fatty acid beta-oxidation" |
| 1139 | YDR257C | SET7 SGDID:S000002665, Chr IV from 971471-969987, reverse complement, Verified ORF, "Nuclear protein that contains a SET-domain, which have been shown to mediate methyltransferase activity in other proteins" |
| 1140 | YDR258C | HSP78 SGDID:S000002666, Chr IV from 974240-971805, reverse complement, Verified ORF, "Oligomeric mitochondrial matrix chaperone that cooperates with Ssc1p in mitochondrial thermotolerance after heat shock; prevents the aggregation of misfolded matrix proteins; component of the mitochondrial proteolysis system" |
| 1141 | YDR259C | YAP6 SGDID:S000002667, Chr IV from 975779-974628, reverse complement, Verified ORF, "Putative basic leucine zipper (bZIP) transcription factor; overexpression increases sodium and lithium tolerance" |
| 1142 | YDR260C | SWM1 SGDID:S000002668, Chr IV from 977226-976714, reverse complement, Verified ORF, "Subunit of the anaphase-promoting complex, which is an E3 ubiquitin ligase that regulates the metaphase-anaphase transition and exit from mitosis; required for activation of the daughter-specific gene expression and spore wall maturation" |
| 1143 | YDR261C | EXG2 SGDID:S000002669, Chr IV from 979206-977518, reverse complement, Verified ORF, "Exo-1,3-beta-glucanase, involved in cell wall beta-glucan assembly; may be anchored to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" |
| 1144 | YDR261C-C | YDR261C-C SGDID:S000007394, Chr IV from 992346-991024, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; in YDRCTY1-3 TYB is mutant and probably non-functional" |
| 1145 | YDR261C-D | YDR261C-D SGDID:S000007395, Chr IV from 992346-991042,991040-987531, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; in YDRCTY1-3 TYB is mutant and probably non-functional" |
| 1146 | YDR261W-A | YDR261W-A SGDID:S000007396, Chr IV from 981459-982775, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 1147 | YDR261W-B | YDR261W-B SGDID:S000007397, Chr IV from 981459-982751,982753-986772, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 1148 | YDR262W | YDR262W SGDID:S000002670, Chr IV from 993131-993949, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole and is induced in response to the DNA-damaging agent MMS; gene expression increases in response to Zymoliase treatment" |
| 1149 | YDR263C | DIN7 SGDID:S000002671, Chr IV from 995531-994239, reverse complement, Verified ORF, "Mitochondrial nuclease functioning in DNA repair and replication, modulates the stability of the mitochondrial genome, induced by exposure to mutagens, also induced during meiosis at a time nearly coincident with commitment to recombination" |
| 1150 | YDR264C | AKR1 SGDID:S000002672, Chr IV from 998320-996026, reverse complement, Verified ORF, "Palmitoyl transferase involved in protein palmitoylation; acts as a negative regulator of pheromone response pathway; required for endocytosis of pheromone receptors; involved in cell shape control; contains ankyrin repeats" |
| 1151 | YDR265W | PEX10 SGDID:S000002673, Chr IV from 998861-999874, Verified ORF, "C3HC4-type RING-finger peroxisomal membrane peroxin required for peroxisomal matrix protein import, interacts with Pex12p, links ubiquitin-conjugating Pex4p to import machinery; mutations in human homolog cause various peroxisomal disorders" |
| 1152 | YDR266C | YDR266C SGDID:S000002674, Chr IV from 1002020-1000101, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments;green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; contains a RING finger domain" |
| 1153 | YDR267C | CIA1 SGDID:S000002675, Chr IV from 1003499-1002507, reverse complement, Verified ORF, "Essential protein involved in assembly of cytosolic and nuclear iron-sulfur proteins" |
| 1154 | YDR268W | MSW1 SGDID:S000002676, Chr IV from 1004001-1005140, Verified ORF, "Mitochondrial tryptophanyl-tRNA synthetase" |
| 1155 | YDR270W | CCC2 SGDID:S000002678, Chr IV from 1005672-1008686, Verified ORF, "Cu(+2)-transporting P-type ATPase, required for export of copper from the cytosol into an extracytosolic compartment; has similarity to human proteins involved in Menkes and Wilsons diseases" |
| 1156 | YDR272W | GLO2 SGDID:S000002680, Chr IV from 1009007-1009831, Verified ORF, "Cytoplasmic glyoxalase II, catalyzes the hydrolysis of S-D-lactoylglutathione into glutathione and D-lactate" |
| 1157 | YDR273W | DON1 SGDID:S000002681, Chr IV from 1010173-1011270, Verified ORF, "Meiosis-specific component of the spindle pole body, part of the leading edge protein (LEP) coat, forms a ring-like structure at the leading edge of the prospore membrane during meiosis II" |
| 1158 | YDR275W | BSC2 SGDID:S000002683, Chr IV from 1012249-1012956, Verified ORF, "Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression" |
| 1159 | YDR276C | PMP3 SGDID:S000002684, Chr IV from 1013640-1013473, reverse complement, Verified ORF, "Small plasma membrane protein related to a family of plant polypeptides that are overexpressed under high salt concentration or low temperature, not essential for viability, deletion causes hyperpolarization of the plasma membrane potential" |
| 1160 | YDR277C | MTH1 SGDID:S000002685, Chr IV from 1015699-1014398, reverse complement, Verified ORF, "Negative regulator of the glucose-sensing signal transduction pathway, required for repression of transcription by Rgt1p; interacts with Rgt1p and the Snf3p and Rgt2p glucose sensors; phosphorylated by Yck1p, triggering Mth1p degradation" |
| 1161 | YDR279W | RNH202 SGDID:S000002687, Chr IV from 1019365-1020417, Verified ORF, "Ribonuclease H2 subunit, required for RNase H2 activity" |
| 1162 | YDR280W | RRP45 SGDID:S000002688, Chr IV from 1020744-1021661, Verified ORF, "Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex" |
| 1163 | YDR281C | PHM6 SGDID:S000002689, Chr IV from 1022318-1022004, reverse complement, Verified ORF, "Protein of unknown function, expression is regulated by phosphate levels" |
| 1164 | YDR282C | YDR282C SGDID:S000002690, Chr IV from 1024752-1023508, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1165 | YDR283C | GCN2 SGDID:S000002691, Chr IV from 1030046-1025067, reverse complement, Verified ORF, "Protein kinase, phosphorylates the alpha-subunit of translation initiation factor eIF2 (Sui2p) in response to starvation; activated by uncharged tRNAs and the Gcn1p-Gcn20p complex" |
| 1166 | YDR284C | DPP1 SGDID:S000002692, Chr IV from 1031416-1030547, reverse complement, Verified ORF, "Diacylglycerol pyrophosphate (DGPP) phosphatase, zinc-regulated vacuolar membrane-associated lipid phosphatase, dephosphorylates DGPP to phosphatidate (PA) and Pi, then PA to diacylglycerol; involved in lipid signaling and cell metabolism" |
| 1167 | YDR285W | ZIP1 SGDID:S000002693, Chr IV from 1032433-1035060, Verified ORF, "Transverse filament protein of the synaptonemal complex; required for normal levels of meiotic recombination and pairing between homologous chromosome during meiosis; potential Cdc28p substrate" |
| 1168 | YDR286C | YDR286C SGDID:S000002694, Chr IV from 1035572-1035228, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; predicted to have thiol-disulfide oxidoreductase active site" |
| 1169 | YDR287W | INM2 SGDID:S000002695, Chr IV from 1035992-1036870, Verified ORF, "Inositol monophosphatase, involved in biosynthesis of inositol; enzymatic activity requires magnesium ions and is inhibited by lithium and sodium ions; inm1 inm2 double mutant lacks inositol auxotrophy" |
| 1170 | YDR288W | NSE3 SGDID:S000002696, Chr IV from 1037192-1038103, Verified ORF, "Essential subunit of the Mms21-Smc5-Smc6 complex; protein of unknown function; required for DNA repair and growth" |
| 1171 | YDR289C | RTT103 SGDID:S000002697, Chr IV from 1039506-1038277, reverse complement, Verified ORF, "Protein that interacts with exonuclease Rat1p and Rai1p and plays a role in transcription termination by RNA polymerase II, has an RPR domain (carboxy-terminal domain interacting domain); also involved in regulation of Ty1 transposition" |
| 1172 | YDR291W | YDR291W SGDID:S000002699, Chr IV from 1039725-1042958, Uncharacterized ORF, "Putative DNA helicase" |
| 1173 | YDR292C | SRP101 SGDID:S000002700, Chr IV from 1045008-1043143, reverse complement, Verified ORF, "Signal recognition particle (SRP) receptor - alpha subunit; contain GTPase domains; involved in SRP-dependent protein targeting; interacts with SRP102p" |
| 1174 | YDR293C | SSD1 SGDID:S000002701, Chr IV from 1049389-1045637, reverse complement, Verified ORF, "Protein with a role in maintenance of cellular integrity, interacts with components of the TOR pathway; ssd1 mutant of a clinical S. cerevisiae strain displays elevated virulence" |
| 1175 | YDR294C | DPL1 SGDID:S000002702, Chr IV from 1052225-1050456, reverse complement, Verified ORF, "Dihydrosphingosine phosphate lyase, regulates intracellular levels of sphingolipid long-chain base phosphates (LCBPs), degrades phosphorylated long chain bases, prefers C16 dihydrosphingosine-l-phosphate as a substrate" |
| 1176 | YDR295C | HDA2 SGDID:S000002703, Chr IV from 1054644-1052620, reverse complement, Verified ORF, "Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex containing an Hda1p homodimer and an Hda2p-Hda3p heterodimer; involved in telomere maintenance" |
| 1177 | YDR296W | MHR1 SGDID:S000002704, Chr IV from 1055209-1055889, Verified ORF, "Protein involved in homologous recombination in mitochondria and in transcription regulation in nucleus; binds to activation domains of acidic activators; required for recombination-dependent mtDNA partitioning" |
| 1178 | YDR297W | SUR2 SGDID:S000002705, Chr IV from 1056548-1057597, Verified ORF, "Sphinganine C4-hydroxylase, catalyses the conversion of sphinganine to phytosphingosine in sphingolipid biosyntheis" |
| 1179 | YDR298C | ATP5 SGDID:S000002706, Chr IV from 1058811-1058173, reverse complement, Verified ORF, "Subunit 5 of the stator stalk of mitochondrial F1F0 ATP synthase, which is an evolutionarily conserved enzyme complex required for ATP synthesis; homologous to bovine subunit OSCP (oligomycin sensitivity-conferring protein); phosphorylated" |
| 1180 | YDR299W | BFR2 SGDID:S000002707, Chr IV from 1059624-1061228, Verified ORF, "Essential protein possibly involved in secretion; multicopy suppressor of sensitivity to Brefeldin A" |
| 1181 | YDR300C | PRO1 SGDID:S000002708, Chr IV from 1062788-1061502, reverse complement, Verified ORF, "Gamma-glutamyl kinase, catalyzes the first step in proline biosynthesis" |
| 1182 | YDR301W | CFT1 SGDID:S000002709, Chr IV from 1063349-1067422, Verified ORF, "RNA-binding subunit of the mRNA cleavage and polyadenylation factor; involved in poly(A) site recognition and required for both pre-mRNA cleavage and polyadenylation, 51% sequence similarity with mammalian AAUAA-binding subunit of CPSF" |
| 1183 | YDR302W | GPI11 SGDID:S000002710, Chr IV from 1067728-1068387, Verified ORF, "ER membrane protein involved in a late step of glycosylphosphatidylinositol (GPI) anchor assembly; involved in the addition of phosphoethanolamine to the multiply mannosylated GPI intermediate; human PIG-Fp is a functional homolog" |
| 1184 | YDR303C | RSC3 SGDID:S000002711, Chr IV from 1071383-1068726, reverse complement, Verified ORF, "Component of the RSC chromatin remodeling complex; essential gene required for maintenance of proper ploidy and regulation of ribosomal protein genes and the cell wall/stress response; highly similar to Rsc30p" |
| 1185 | YDR304C | CPR5 SGDID:S000002712, Chr IV from 1072554-1071877, reverse complement, Verified ORF, "Peptidyl-prolyl cis-trans isomerase (cyclophilin) of the endoplasmic reticulum, catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; transcriptionally induced in response to unfolded proteins in the ER" |
| 1186 | YDR305C | HNT2 SGDID:S000002713, Chr IV from 1073485-1073399,1073309-1072743, reverse complement, Verified ORF, "Dinucleoside triphosphate hydrolase; has similarity to the tumor suppressor FHIT and belongs to the histidine triad (HIT) superfamily of nucleotide-binding proteins" |
| 1187 | YDR306C | YDR306C SGDID:S000002714, Chr IV from 1075168-1073732, reverse complement, Uncharacterized ORF, "F-box protein of unknown function; interacts with Sgt1p via a Leucine-Rich Repeat (LRR) domain" |
| 1188 | YDR307W | YDR307W SGDID:S000002715, Chr IV from 1075862-1077850, Uncharacterized ORF, "Putative protein of unknown function" |
| 1189 | YDR308C | SRB7 SGDID:S000002716, Chr IV from 1078446-1078024, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; target of the global repressor Tup1p" |
| 1190 | YDR309C | GIC2 SGDID:S000002717, Chr IV from 1080196-1079045, reverse complement, Verified ORF, "Redundant rho-like GTPase Cdc42p effector; homolog of Gic1p; involved in initiation of budding and cellular polarization; interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain and with PI(4,5)P2 via a polybasic region" |
| 1191 | YDR310C | SUM1 SGDID:S000002718, Chr IV from 1084313-1081125, reverse complement, Verified ORF, "Transcriptional repressor required for mitotic repression of middle sporulation-specific genes; involved in telomere maintenance, regulated by the pachytene checkpoint" |
| 1192 | YDR311W | TFB1 SGDID:S000002719, Chr IV from 1085063-1086991, Verified ORF, "Subunit of TFIIH and nucleotide excision repair factor 3 complexes, required for nucleotide excision repair, target for transcriptional activators" |
| 1193 | YDR312W | SSF2 SGDID:S000002720, Chr IV from 1087579-1088940, Verified ORF, "Protein required for ribosomal large subunit maturation, functionally redundant with Ssf1p; member of the Brix family" |
| 1194 | YDR313C | PIB1 SGDID:S000002721, Chr IV from 1090077-1089217, reverse complement, Verified ORF, "RING-type ubiquitin ligase of the endosomal and vacuolar membranes, binds phosphatidylinositol(3)-phosphate; contains a FYVE finger domain" |
| 1195 | YDR314C | RAD34 SGDID:S000002722, Chr IV from 1092509-1090431, reverse complement, Verified ORF, "Protein involved in nucleotide excision repair (NER); homologous to RAD4" |
| 1196 | YDR315C | IPK1 SGDID:S000002723, Chr IV from 1093584-1092739, reverse complement, Verified ORF, "Inositol 1,3,4,5,6-pentakisphosphate 2-kinase, nuclear protein required for synthesis of 1,2,3,4,5,6-hexakisphosphate (phytate), which is integral to cell function; has 2 motifs conserved in other fungi; ipk1 gle1 double mutant is inviable" |
| 1197 | YDR316W | OMS1 SGDID:S000002724, Chr IV from 1093761-1095176, Verified ORF, "Protein integral to the mitochondrial membrane; has a conserved methyltransferase motif; multicopy suppressor of respiratory defects caused by OXA1 mutations" |
| 1198 | YDR316W-A | YDR316W-A SGDID:S000007398, Chr IV from 1096062-1097384, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 1199 | YDR316W-B | YDR316W-B SGDID:S000007399, Chr IV from 1096062-1097366,1097368-1101330, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 1200 | YDR317W | HIM1 SGDID:S000002725, Chr IV from 1102182-1103426, Verified ORF, "Protein of unknown function involved in DNA repair" |
| 1201 | YDR318W | MCM21 SGDID:S000002726, Chr IV from 1103756-1103807,1103891-1104945, Verified ORF, "Protein involved in minichromosome maintenance; component of the COMA complex (Ctf19p, Okp1p, Mcm21p, Ame1p) that bridges kinetochore subunits that are in contact with centromeric DNA and the subunits bound to microtubules" |
| 1202 | YDR319C | YDR319C SGDID:S000002727, Chr IV from 1105825-1105001, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, identified as an ortholog of the highly conserved FIT family of proteins involved in triglyceride droplet biosynthesis; interacts with Sst2p and Hsp82p in high-throughput two-hybrid screens" |
| 1203 | YDR320C | SWA2 SGDID:S000002728, Chr IV from 1108099-1106093, reverse complement, Verified ORF, "Auxilin-like protein involved in vesicular transport; clathrin-binding protein required for uncoating of clathrin-coated vesicles" |
| 1204 | YDR320C-A | DAD4 SGDID:S000007604, Chr IV from 1108496-1108278, reverse complement, Verified ORF, "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" |
| 1205 | YDR321W | ASP1 SGDID:S000002729, Chr IV from 1108700-1109845, Verified ORF, "Cytosolic L-asparaginase, involved in asparagine catabolism" |
| 1206 | YDR322C-A | TIM11 SGDID:S000007255, Chr IV from 1112291-1112001, reverse complement, Verified ORF, "Subunit e of mitochondrial F1F0-ATPase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; essential for the dimeric and oligomeric state of ATP synthase" |
| 1207 | YDR322W | MRPL35 SGDID:S000002730, Chr IV from 1110587-1111690, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 1208 | YDR323C | PEP7 SGDID:S000002731, Chr IV from 1114025-1112478, reverse complement, Verified ORF, "Multivalent adaptor protein that facilitates vesicle-mediated vacuolar protein sorting by ensuring high-fidelity vesicle docking and fusion, which are essential for targeting of vesicles to the endosome; required for vacuole inheritance" |
| 1209 | YDR324C | UTP4 SGDID:S000002732, Chr IV from 1116761-1114431, reverse complement, Verified ORF, "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" |
| 1210 | YDR325W | YCG1 SGDID:S000002733, Chr IV from 1117122-1120229, Verified ORF, "Non-SMC subunit of the condensin complex (Smc2p-Smc4p-Ycs4p-Brn1p-Ycg1p); required for establishment and maintenance of chromosome condensation, chromosome segregation and for chromatin binding of the condensin complex" |
| 1211 | YDR326C | YSP2 SGDID:S000002734, Chr IV from 1124921-1120605, reverse complement, Verified ORF, "Protein involved in programmed cell death; mutant shows resistance to cell death induced by amiodarone or intracellular acidification" |
| 1212 | YDR328C | SKP1 SGDID:S000002736, Chr IV from 1126014-1125430, reverse complement, Verified ORF, "Evolutionarily conserved kinetochore protein that is part of multiple protein complexes, including the SCF ubiquitin ligase complex, the CBF3 complex that binds centromeric DNA, and the RAVE complex that regulates assembly of the V-ATPase" |
| 1213 | YDR329C | PEX3 SGDID:S000002737, Chr IV from 1127591-1126266, reverse complement, Verified ORF, "Peroxisomal membrane protein (PMP) required required for the proper localization and stability of PMPs; interacts with Pex19p" |
| 1214 | YDR330W | UBX5 SGDID:S000002738, Chr IV from 1127868-1129370, Verified ORF, "UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p" |
| 1215 | YDR331W | GPI8 SGDID:S000002739, Chr IV from 1129584-1130819, Verified ORF, "ER membrane glycoprotein subunit of the glycosylphosphatidylinositol transamidase complex that adds glycosylphosphatidylinositol (GPI) anchors to newly synthesized proteins; human PIG-K protein is a functional homolog" |
| 1216 | YDR332W | IRC3 SGDID:S000002740, Chr IV from 1130997-1133066, Verified ORF, "Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion" |
| 1217 | YDR333C | YDR333C SGDID:S000002741, Chr IV from 1135427-1133256, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1218 | YDR334W | SWR1 SGDID:S000002742, Chr IV from 1135928-1140472, Verified ORF, "Swi2/Snf2-related ATPase that is the structural component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A" |
| 1219 | YDR335W | MSN5 SGDID:S000002743, Chr IV from 1141163-1144837, Verified ORF, "Karyopherin involved in nuclear import and export; shown to be responsible for nuclear import of replication protein A and for export of several proteins including Swi6p, Far1p, and Pho4p; cargo dissociation involves binding to RanGTP" |
| 1220 | YDR336W | YDR336W SGDID:S000002744, Chr IV from 1145087-1146031, Uncharacterized ORF, "Putative protein of unknown function; sumoylated under stress conditions in a genome wide study; YDR336W is not an essential gene" |
| 1221 | YDR337W | MRPS28 SGDID:S000002745, Chr IV from 1146314-1147174, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 1222 | YDR338C | YDR338C SGDID:S000002746, Chr IV from 1149461-1147374, reverse complement, Uncharacterized ORF, "Hypothetical protein" |
| 1223 | YDR339C | FCF1 SGDID:S000002747, Chr IV from 1150515-1149946, reverse complement, Verified ORF, "Essential nucleolar protein that is a component of the SSU (small subunit) processome involved in the pre-rRNA processing steps of 40S ribosomal subunit biogenesis; contains a PINc domain; copurifies with Faf1p" |
| 1224 | YDR341C | YDR341C SGDID:S000002749, Chr IV from 1153621-1151798, reverse complement, Verified ORF, "Arginyl-tRNA synthetase, proposed to be cytoplasmic but the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 1225 | YDR342C | HXT7 SGDID:S000002750, Chr IV from 1155923-1154211, reverse complement, Verified ORF, "High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt6p, expressed at high basal levels relative to other HXTs, expression repressed by high glucose levels" |
| 1226 | YDR343C | HXT6 SGDID:S000002751, Chr IV from 1161315-1159603, reverse complement, Verified ORF, "High-affinity glucose transporter of the major facilitator superfamily, nearly identical to Hxt7p, expressed at high basal levels relative to other HXTs, repression of expression by high glucose requires SNF3" |
| 1227 | YDR345C | HXT3 SGDID:S000002753, Chr IV from 1164655-1162952, reverse complement, Verified ORF, "Low affinity glucose transporter of the major facilitator superfamily, expression is induced in low or high glucose conditions" |
| 1228 | YDR346C | SVF1 SGDID:S000002754, Chr IV from 1168654-1167209, reverse complement, Verified ORF, "Protein with a potential role in cell survival pathways, required for the diauxic growth shift; expression in mammalian cells increases survival under conditions inducing apoptosis" |
| 1229 | YDR347W | MRP1 SGDID:S000002755, Chr IV from 1169173-1170138, Verified ORF, "Mitochondrial ribosomal protein of the small subunit; MRP1 exhibits genetic interactions with PET122, encoding a COX3-specific translational activator, and with PET123, encoding a small subunit mitochondrial ribosomal protein" |
| 1230 | YDR348C | YDR348C SGDID:S000002756, Chr IV from 1171820-1170321, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud neck; potential Cdc28p substrate" |
| 1231 | YDR349C | YPS7 SGDID:S000002757, Chr IV from 1174171-1172381, reverse complement, Verified ORF, "Putative GPI-anchored aspartic protease, located in the cytoplasm and endoplasmic reticulum" |
| 1232 | YDR350C | ATP22 SGDID:S000002758, Chr IV from 1178168-1176333, reverse complement, Verified ORF, "Mitochondrial inner membrane protein required for assembly of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" |
| 1233 | YDR351W | SBE2 SGDID:S000002759, Chr IV from 1178660-1181254, Verified ORF, "Protein involved in the transport of cell wall components from the Golgi to the cell surface; required for bud growth" |
| 1234 | YDR352W | YDR352W SGDID:S000002760, Chr IV from 1181795-1182748, Uncharacterized ORF, "Putative protein of unknown function" |
| 1235 | YDR353W | TRR1 SGDID:S000002761, Chr IV from 1183293-1184252, Verified ORF, "Cytoplasmic thioredoxin reductase, key regulatory enzyme that determines the redox state of the thioredoxin system, which acts as a disulfide reductase system and protects cells against both oxidative and reductive stress" |
| 1236 | YDR354W | TRP4 SGDID:S000002762, Chr IV from 1184741-1185883, Verified ORF, "Anthranilate phosphoribosyl transferase of the tryptophan biosynthetic pathway, catalyzes the phosphoribosylation of anthranilate, subject to the general control system of amino acid biosynthesis" |
| 1237 | YDR356W | SPC110 SGDID:S000002764, Chr IV from 1186101-1188935, Verified ORF, "Inner plaque spindle pole body (SPB) component, ortholog of human kendrin; involved in connecting nuclear microtubules to SPB; interacts with Tub4p-complex and calmodulin; phosphorylated by Mps1p in cell cycle-dependent manner" |
| 1238 | YDR357C | YDR357C SGDID:S000002765, Chr IV from 1189561-1189193, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 1239 | YDR358W | GGA1 SGDID:S000002766, Chr IV from 1190053-1191726, Verified ORF, "Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi" |
| 1240 | YDR359C | EAF1 SGDID:S000002767, Chr IV from 1194878-1191930, reverse complement, Verified ORF, "Component of the NuA4 histone acetyltransferase complex; required for initiation of pre-meiotic DNA replication, probably due to its requirement for significant expression of IME1" |
| 1241 | YDR361C | BCP1 SGDID:S000002769, Chr IV from 1196256-1195405, reverse complement, Verified ORF, "Essential protein involved in nuclear export of Mss4p, which is a lipid kinase that generates phosphatidylinositol 4,5-biphosphate and plays a role in actin cytoskeleton organization and vesicular transport" |
| 1242 | YDR362C | TFC6 SGDID:S000002770, Chr IV from 1198690-1196672, reverse complement, Verified ORF, "One of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; cooperates with Tfc3p in DNA binding; human homolog is TFIIIC-110" |
| 1243 | YDR363W | ESC2 SGDID:S000002771, Chr IV from 1199176-1200546, Verified ORF, "Protein involved in mating-type locus silencing, interacts with Sir2p; probably functions to recruit or stabilize Sir proteins" |
| 1244 | YDR363W-A | SEM1 SGDID:S000007235, Chr IV from 1202121-1202390, Verified ORF, "Component of the lid subcomplex of the regulatory subunit of the 26S proteasome; ortholog of human DSS1" |
| 1245 | YDR364C | CDC40 SGDID:S000002772, Chr IV from 1204203-1202836, reverse complement, Verified ORF, "Pre-mRNA splicing factor, important for catalytic step II of pre-mRNA splicing and plays a role in cell cycle progression; required for DNA synthesis during mitosis and meiosis; has WD repeats" |
| 1246 | YDR365C | ESF1 SGDID:S000002773, Chr IV from 1206376-1204490, reverse complement, Verified ORF, "Nucleolar protein involved in pre-rRNA processing; depletion causes severely decreased 18S rRNA levels" |
| 1247 | YDR365W-A | YDR365W-A SGDID:S000007400, Chr IV from 1206990-1208312, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 1248 | YDR365W-B | YDR365W-B SGDID:S000007401, Chr IV from 1206990-1208294,1208296-1212258, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 1249 | YDR366C | YDR366C SGDID:S000002774, Chr IV from 1212829-1212431, reverse complement, Uncharacterized ORF, "Hypothetical protein" |
| 1250 | YDR367W | YDR367W SGDID:S000002775, Chr IV from 1212841-1212870,1212972-1213607, Uncharacterized ORF, "Component of the inositol phosphorylceramide synthase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 1251 | YDR368W | YPR1 SGDID:S000002776, Chr IV from 1213897-1214835, Verified ORF, "2-methylbutyraldehyde reductase, may be involved in isoleucine catabolism" |
| 1252 | YDR369C | XRS2 SGDID:S000002777, Chr IV from 1217573-1215009, reverse complement, Verified ORF, "Protein required for DNA repair; component of the Mre11 complex, which is involved in double strand breaks, meiotic recombination, telomere maintenance, and checkpoint signaling" |
| 1253 | YDR370C | YDR370C SGDID:S000002778, Chr IV from 1219103-1217775, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1254 | YDR371W | CTS2 SGDID:S000002779, Chr IV from 1219406-1220941, Uncharacterized ORF, "Sporulation-specific chitinase" |
| 1255 | YDR372C | VPS74 SGDID:S000002780, Chr IV from 1222142-1221105, reverse complement, Verified ORF, "Protein required for Golgi localization of glycosyltransferases; binds the cytosolic domains of Golgi glycosyltransferases; functions as a heterotetramer" |
| 1256 | YDR373W | FRQ1 SGDID:S000002781, Chr IV from 1222752-1223324, Verified ORF, "N-myristoylated calcium-binding protein that may have a role in intracellular signaling through its regulation of the phosphatidylinositol 4-kinase Pik1p; member of the recoverin/frequenin branch of the EF-hand superfamily" |
| 1257 | YDR374C | YDR374C SGDID:S000002782, Chr IV from 1224387-1223467, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1258 | YDR374W-A | YDR374W-A SGDID:S000113553, Chr IV from 1224750-1225019, Uncharacterized ORF, "Putative protein of unknown function" |
| 1259 | YDR375C | BCS1 SGDID:S000002783, Chr IV from 1226529-1225159, reverse complement, Verified ORF, "Protein of the mitochondrial inner membrane that functions as an ATP-dependent chaperone, required for the incorporation of the Rip1p and Qcr10p subunits into the cytochrome bc(1) complex; member of the CDC48/PAS1/SEC18 ATPase family" |
| 1260 | YDR376W | ARH1 SGDID:S000002784, Chr IV from 1226815-1228296, Verified ORF, "Oxidoreductase of the mitochondrial inner membrane, involved in cytoplasmic and mitochondrial iron homeostasis and required for activity of Fe-S cluster-containing enzymes; one of the few mitochondrial proteins essential for viability" |
| 1261 | YDR377W | ATP17 SGDID:S000002785, Chr IV from 1228604-1228909, Verified ORF, "Subunit f of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" |
| 1262 | YDR378C | LSM6 SGDID:S000002786, Chr IV from 1229602-1229342, reverse complement, Verified ORF, "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" |
| 1263 | YDR379C-A | YDR379C-A SGDID:S000007605, Chr IV from 1233510-1233271, reverse complement, Uncharacterized ORF, "Hypothetical protein identified by homology. See FEBS Letters [2000] 487:31-36." |
| 1264 | YDR379W | RGA2 SGDID:S000002787, Chr IV from 1230160-1233189, Verified ORF, "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth; regulated by Pho85p and Cdc28p" |
| 1265 | YDR380W | ARO10 SGDID:S000002788, Chr IV from 1234211-1236118, Verified ORF, "Phenylpyruvate decarboxylase, catalyzes decarboxylation of phenylpyruvate to phenylacetaldehyde, which is the first specific step in the Ehrlich pathway" |
| 1266 | YDR381C-A | YDR381C-A SGDID:S000007650, Chr IV from 1238843-1238818,1238623-1238305, reverse complement, Verified ORF, "Protein of unknown function, localized to the mitochondrial outer membrane" |
| 1267 | YDR381W | YRA1 SGDID:S000002789, Chr IV from 1236551-1236835,1237602-1237997, Verified ORF, "Nuclear protein that binds to RNA and to Mex67p, required for export of poly(A)+ mRNA from the nucleus; member of the REF (RNA and export factor binding proteins) family; another family member, Yra2p, can substitute for Yra1p function" |
| 1268 | YDR382W | RPP2B SGDID:S000002790, Chr IV from 1239485-1239817, Verified ORF, "Ribosomal protein P2 beta, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm" |
| 1269 | YDR383C | NKP1 SGDID:S000002791, Chr IV from 1240669-1239953, reverse complement, Verified ORF, "Non-essential kinetochore protein, subunit of the Ctf19 central kinetochore complex (Ctf19p-Mcm21p-Okp1p-Mcm22p-Mcm16p-Ctf3p-Chl4p-Mcm19p-Nkp1p-Nkp2p-Ame1p-Mtw1p)" |
| 1270 | YDR384C | ATO3 SGDID:S000002792, Chr IV from 1242024-1241197, reverse complement, Verified ORF, "Plasma membrane protein, regulation pattern suggests a possible role in export of ammonia from the cell; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family of putative transporters" |
| 1271 | YDR385W | EFT2 SGDID:S000002793, Chr IV from 1243223-1245751, Verified ORF, "Elongation factor 2 (EF-2), also encoded by EFT1; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin" |
| 1272 | YDR386W | MUS81 SGDID:S000002794, Chr IV from 1246077-1247975, Verified ORF, "Helix-hairpin-helix protein, involved in DNA repair and replication fork stability; functions as an endonuclease in complex with Mms4p; interacts with Rad54p" |
| 1273 | YDR387C | YDR387C SGDID:S000002795, Chr IV from 1249814-1248147, reverse complement, Uncharacterized ORF, "Putative transporter, member of the sugar porter family; YDR387C is not an essential gene" |
| 1274 | YDR388W | RVS167 SGDID:S000002796, Chr IV from 1250179-1251627, Verified ORF, "Actin-associated protein, subunit of a complex (Rvs161p-Rvs167p) involved in regulation of actin cytoskeleton, endocytosis, and viability following starvation or osmotic stress; homolog of mammalian amphiphysin" |
| 1275 | YDR389W | SAC7 SGDID:S000002797, Chr IV from 1252530-1254494, Verified ORF, "GTPase activating protein (GAP) for Rho1p, involved in signaling to the actin cytoskeleton, null mutations suppress tor2 mutations and temperature sensitive mutations in actin; potential Cdc28p substrate" |
| 1276 | YDR390C | UBA2 SGDID:S000002798, Chr IV from 1256840-1254930, reverse complement, Verified ORF, "Nuclear protein that acts as a heterodimer with Aos1p to activate Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability" |
| 1277 | YDR391C | YDR391C SGDID:S000002799, Chr IV from 1258049-1257351, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, possibly involved in zinc homeostasis; Bdf1p-dependent transcription induced by salt stress; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus" |
| 1278 | YDR392W | SPT3 SGDID:S000002800, Chr IV from 1258689-1259702, Verified ORF, "Subunit of the SAGA and SAGA-like transcriptional regulatory complexes, interacts with Spt15p to activate transcription of some RNA polymerase II-dependent genes, also functions to inhibit transcription at some promoters" |
| 1279 | YDR393W | SHE9 SGDID:S000002801, Chr IV from 1259894-1261264, Verified ORF, "Mitochondrial inner membrane protein required for normal mitochondrial morphology, may be involved in fission of the inner membrane; forms a homo-oligomeric complex" |
| 1280 | YDR394W | RPT3 SGDID:S000002802, Chr IV from 1261674-1262960, Verified ORF, "One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; substrate of N-acetyltransferase B" |
| 1281 | YDR395W | SXM1 SGDID:S000002803, Chr IV from 1263317-1266151, Verified ORF, "Nuclear transport factor (karyopherin) involved in protein transport between the cytoplasm and nucleoplasm; similar to Nmd5p, Cse1p, Lph2p, and the human cellular apoptosis susceptibility protein, CAS1" |
| 1282 | YDR397C | NCB2 SGDID:S000002805, Chr IV from 1266891-1266855,1266762-1266359, reverse complement, Verified ORF, "Subunit of a heterodimeric NC2 transcription regulator complex with Bur6p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2beta" |
| 1283 | YDR398W | UTP5 SGDID:S000002806, Chr IV from 1267464-1269395, Verified ORF, "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" |
| 1284 | YDR399W | HPT1 SGDID:S000002807, Chr IV from 1270061-1270726, Verified ORF, "Dimeric hypoxanthine-guanine phosphoribosyltransferase, catalyzes the formation of both inosine monophosphate and guanosine monophosphate; mutations in the human homolog HPRT1 can cause Lesch-Nyhan syndrome and Kelley-Seegmiller syndrome" |
| 1285 | YDR400W | URH1 SGDID:S000002808, Chr IV from 1271056-1272078, Verified ORF, "Uridine nucleosidase (uridine-cytidine N-ribohydrolase), cleaves N-glycosidic bonds in nucleosides; involved in the pyrimidine salvage and nicotinamide riboside salvage pathways" |
| 1286 | YDR402C | DIT2 SGDID:S000002810, Chr IV from 1273696-1272227, reverse complement, Verified ORF, "N-formyltyrosine oxidase, sporulation-specific microsomal enzyme involved in the production of N,N-bisformyl dityrosine required for spore wall maturation, homologous to cytochrome P-450s" |
| 1287 | YDR403W | DIT1 SGDID:S000002811, Chr IV from 1274595-1276205, Verified ORF, "Sporulation-specific enzyme required for spore wall maturation, involved in the production of a soluble LL-dityrosine-containing precursor of the spore wall; transcripts accumulate at the time of prospore enclosure" |
| 1288 | YDR404C | RPB7 SGDID:S000002812, Chr IV from 1277162-1276647, reverse complement, Verified ORF, "RNA polymerase II subunit B16; forms two subunit dissociable complex with Rpb4p" |
| 1289 | YDR405W | MRP20 SGDID:S000002813, Chr IV from 1277639-1278430, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 1290 | YDR406W | PDR15 SGDID:S000002814, Chr IV from 1279203-1283792, Verified ORF, "Plasma membrane ATP binding cassette (ABC) transporter, multidrug transporter and general stress response factor implicated in cellular detoxification; regulated by Pdr1p, Pdr3p and Pdr8p; promoter contains a PDR responsive element" |
| 1291 | YDR407C | TRS120 SGDID:S000002815, Chr IV from 1287931-1284062, reverse complement, Verified ORF, "One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic" |
| 1292 | YDR408C | ADE8 SGDID:S000002816, Chr IV from 1288852-1288208, reverse complement, Verified ORF, "Phosphoribosyl-glycinamide transformylase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway" |
| 1293 | YDR409W | SIZ1 SGDID:S000002817, Chr IV from 1289399-1292113, Verified ORF, "SUMO/Smt3 ligase that promotes the attachment of sumo (Smt3p; small ubiquitin-related modifier) to proteins; binds Ubc9p and may bind septins; specifically required for sumoylation of septins in vivo; localized to the septin ring" |
| 1294 | YDR410C | STE14 SGDID:S000002818, Chr IV from 1293084-1292365, reverse complement, Verified ORF, "Farnesyl cysteine-carboxyl methyltransferase, mediates the carboxyl methylation step during C-terminal CAAX motif processing of a-factor and RAS proteins in the endoplasmic reticulum, localizes to the ER membrane" |
| 1295 | YDR411C | DFM1 SGDID:S000002819, Chr IV from 1294387-1293362, reverse complement, Verified ORF, "ER localized derlin-like family member involved in ER stress and homeostasis; not involved in ERAD or substrate retrotranslocation; interacts with CDC48; contains four transmembrane domains and two SHP boxes" |
| 1296 | YDR412W | RRP17 SGDID:S000002820, Chr IV from 1294686-1295393, Uncharacterized ORF, "Component of the pre-60S pre-ribosomal particle; required for cell viability" |
| 1297 | YDR414C | ERD1 SGDID:S000002822, Chr IV from 1296679-1295591, reverse complement, Verified ORF, "Predicted membrane protein required for the retention of lumenal endoplasmic reticulum proteins; mutants secrete the endogenous ER protein, BiP (Kar2p)" |
| 1298 | YDR415C | YDR415C SGDID:S000002823, Chr IV from 1298154-1297030, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1299 | YDR416W | SYF1 SGDID:S000002824, Chr IV from 1298425-1301004, Verified ORF, "Component of the spliceosome complex involved in pre-mRNA splicing; involved in regulation of cell cycle progression; similar to Drosophila crooked neck protein" |
| 1300 | YDR418W | RPL12B SGDID:S000002826, Chr IV from 1301609-1302106, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Ap; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins" |
| 1301 | YDR419W | RAD30 SGDID:S000002827, Chr IV from 1303167-1305065, Verified ORF, "DNA polymerase eta, involved in the predominantly error-free bypass replication of DNA lesions, catalyzes the efficient and accurate synthesis of DNA opposite cyclobutane pyrimidine dimers; homolog of human POLH and bacterial DinB proteins" |
| 1302 | YDR420W | HKR1 SGDID:S000002828, Chr IV from 1306260-1311668, Verified ORF, "Serine/threonine rich cell surface protein; osmosensor; involved in the regulation of cell wall beta-1,3 glucan synthesis, bud site selection and hyperosmotic response; overexpression confers resistance to Hansenula mrakii killer toxin HM-1" |
| 1303 | YDR421W | ARO80 SGDID:S000002829, Chr IV from 1312033-1314885, Verified ORF, "Zinc finger transcriptional activator of the Zn2Cys6 family; activates transcription of aromatic amino acid catabolic genes in the presence of aromatic amino acids" |
| 1304 | YDR422C | SIP1 SGDID:S000002830, Chr IV from 1317766-1315319, reverse complement, Verified ORF, "Alternate beta-subunit of the Snf1p kinase complex, may confer substrate specificity; vacuolar protein containing KIS (Kinase-Interacting Sequence) and ASC (Association with Snf1 kinase Complex) domains involved in protein interactions" |
| 1305 | YDR423C | CAD1 SGDID:S000002831, Chr IV from 1319268-1318039, reverse complement, Verified ORF, "AP-1-like bZIP transcriptional activator involved in stress responses, iron metabolism, and pleiotropic drug resistance; controls a set of genes involved in stabilizing proteins; binds consensus sequence TTACTAA; 5' UTR contains uORFs" |
| 1306 | YDR424C | DYN2 SGDID:S000002832, Chr IV from 1319834-1319810,1319713-1319691,1319610-1319380, reverse complement, Verified ORF, "Cytoplasmic light chain dynein, microtubule motor protein; proposed to be involved in the assembly of the nuclear pore complex" |
| 1307 | YDR425W | SNX41 SGDID:S000002833, Chr IV from 1320057-1321934, Verified ORF, "Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golgi endosome to the trans-Golgi network; interacts with Snx4p" |
| 1308 | YDR427W | RPN9 SGDID:S000002835, Chr IV from 1322198-1323379, Verified ORF, "Non-ATPase regulatory subunit of the 26S proteasome, has similarity to putative proteasomal subunits in other species; null mutant is temperature sensitive and exhibits cell cycle and proteasome assembly defects" |
| 1309 | YDR428C | BNA7 SGDID:S000002836, Chr IV from 1324232-1323447, reverse complement, Verified ORF, "Formylkynurenine formamidase, involved in the de novo biosynthesis of NAD from tryptophan via kynurenine" |
| 1310 | YDR429C | TIF35 SGDID:S000002837, Chr IV from 1325294-1324470, reverse complement, Verified ORF, "Subunit of the core complex of translation initiation factor 3(eIF3), which is essential for translation" |
| 1311 | YDR430C | CYM1 SGDID:S000002838, Chr IV from 1328463-1325494, reverse complement, Verified ORF, "Lysine-specific metalloprotease of the mitochondrial intermembrane space, member of the pitrilysin family; degrades proteins and presequence peptides cleaved from imported proteins; required for normal mitochondrial morphology" |
| 1312 | YDR432W | NPL3 SGDID:S000002840, Chr IV from 1328776-1330020, Verified ORF, "RNA-binding protein that carries poly(A)+ mRNA from the nucleus into the cytoplasm; dissociation from mRNAs is promoted by Mtr10p; phosphorylated by Sky1p in the cytoplasm" |
| 1313 | YDR434W | GPI17 SGDID:S000002842, Chr IV from 1331230-1332834, Verified ORF, "Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase complex that adds GPIs to newly synthesized proteins; human PIG-Sp homolog" |
| 1314 | YDR435C | PPM1 SGDID:S000002843, Chr IV from 1333962-1332976, reverse complement, Verified ORF, "Carboxyl methyltransferase, methylates the C terminus of the protein phosphatase 2A catalytic subunit (Pph21p or Pph22p), which is important for complex formation with regulatory subunits" |
| 1315 | YDR436W | PPZ2 SGDID:S000002844, Chr IV from 1334814-1336946, Verified ORF, "Serine/threonine protein phosphatase Z, isoform of Ppz1p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance" |
| 1316 | YDR437W | GPI19 SGDID:S000002845, Chr IV from 1337345-1337767, Verified ORF, "Subunit of GPI-GlcNAc transferase involved in synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), which is the first intermediate in glycosylphosphatidylinositol (GPI) anchor synthesis, shares similarity with mammalian PIG-P" |
| 1317 | YDR438W | THI74 SGDID:S000002846, Chr IV from 1338267-1339379, Verified ORF, "Mitochondrial transporter repressible by thiamine" |
| 1318 | YDR439W | LRS4 SGDID:S000002847, Chr IV from 1339669-1340712, Verified ORF, "Protein involved in rDNA silencing; positively charged coiled-coil protein with limited similarity to myosin" |
| 1319 | YDR440W | DOT1 SGDID:S000002848, Chr IV from 1342486-1344234, Verified ORF, "Nucleosomal histone H3-Lys79 methylase, associates with transcriptionally active genes, functions in gene silencing at telomeres, most likely by directly modulating chromatin structure and Sir protein localization" |
| 1320 | YDR441C | APT2 SGDID:S000002849, Chr IV from 1345055-1344510, reverse complement, Verified ORF, "Apparent pseudogene, not transcribed or translated under normal conditions; encodes a protein with similarity to adenine phosphoribosyltransferase, but artificially expressed protein exhibits no enzymatic activity" |
| 1321 | YDR443C | SSN2 SGDID:S000002851, Chr IV from 1349931-1345669, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for stable association of Srb10p-Srb11p kinase; essential for transcriptional regulation" |
| 1322 | YDR444W | YDR444W SGDID:S000002852, Chr IV from 1350283-1352346, Uncharacterized ORF, "Putative protein of unknown function" |
| 1323 | YDR446W | ECM11 SGDID:S000002854, Chr IV from 1353718-1354626, Verified ORF, "Non-essential protein apparently involved in meiosis, GFP fusion protein is present in discrete clusters in the nucleus throughout mitosis; may be involved in maintaining chromatin structure" |
| 1324 | YDR447C | RPS17B SGDID:S000002855, Chr IV from 1355546-1355544,1355229-1354822, reverse complement, Verified ORF, "Ribosomal protein 51 (rp51) of the small (40s) subunit; nearly identical to Rps17Ap and has similarity to rat S17 ribosomal protein" |
| 1325 | YDR448W | ADA2 SGDID:S000002856, Chr IV from 1356058-1357362, Verified ORF, "Transcription coactivator, component of the ADA and SAGA transcriptional adaptor/HAT (histone acetyltransferase) complexes" |
| 1326 | YDR449C | UTP6 SGDID:S000002857, Chr IV from 1358895-1357573, reverse complement, Verified ORF, "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" |
| 1327 | YDR450W | RPS18A SGDID:S000002858, Chr IV from 1359916-1359962,1360398-1360791, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Bp and has similarity to E. coli S13 and rat S18 ribosomal proteins" |
| 1328 | YDR451C | YHP1 SGDID:S000002859, Chr IV from 1362174-1361113, reverse complement, Verified ORF, "One of two homeobox transcriptional repressors (see also Yox1p), that bind to Mcm1p and to early cell cycle box (ECB) elements of cell cycle regulated genes, thereby restricting ECB-mediated transcription to the M/G1 interval" |
| 1329 | YDR452W | PPN1 SGDID:S000002860, Chr IV from 1362871-1364895, Verified ORF, "Vacuolar endopolyphosphatase with a role in phosphate metabolism; functions as a homodimer" |
| 1330 | YDR453C | TSA2 SGDID:S000002861, Chr IV from 1365655-1365065, reverse complement, Verified ORF, "Stress inducible cytoplasmic thioredoxin peroxidase; cooperates with Tsa1p in the removal of reactive oxygen, nitrogen and sulfur species using thioredoxin as hydrogen donor; deletion enhances the mutator phenotype of tsa1 mutants" |
| 1331 | YDR454C | GUK1 SGDID:S000002862, Chr IV from 1366820-1366257, reverse complement, Verified ORF, "Guanylate kinase, converts GMP to GDP; required for growth and mannose outer chain elongation of cell wall N-linked glycoproteins" |
| 1332 | YDR456W | NHX1 SGDID:S000002864, Chr IV from 1367478-1369379, Verified ORF, "Endosomal Na+/H+ exchanger, required for intracellular sequestration of Na+; required for osmotolerance to acute hypertonic shock" |
| 1333 | YDR457W | TOM1 SGDID:S000002865, Chr IV from 1369783-1379589, Verified ORF, "E3 ubiquitin ligase of the hect-domain class; has a role in mRNA export from the nucleus and may regulate transcriptional coactivators" |
| 1334 | YDR458C | HEH2 SGDID:S000002866, Chr IV from 1382039-1380048, reverse complement, Verified ORF, "Inner nuclear membrane (INM) protein; contains helix-extension-helix (HEH) motif, nuclear localization signal sequence; targeting to the INM requires the Srp1p-Kap95p karyopherins and the Ran cycle" |
| 1335 | YDR459C | PFA5 SGDID:S000002867, Chr IV from 1383436-1382312, reverse complement, Verified ORF, "Palmitoyltransferase with autoacylation activity; likely functions in pathway(s) outside Ras; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain" |
| 1336 | YDR460W | TFB3 SGDID:S000002868, Chr IV from 1383804-1384769, Verified ORF, "Subunit of TFIIH and nucleotide excision repair factor 3 complexes, involved in transcription initiation, required for nucleotide excision repair; ring finger protein similar to mammalian CAK and TFIIH subunit" |
| 1337 | YDR461C-A | YDR461C-A SGDID:S000087209, Chr IV from 1385759-1385517, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1338 | YDR461W | MFA1 SGDID:S000002869, Chr IV from 1385169-1385279, Verified ORF, "Mating pheromone a-factor, made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA2" |
| 1339 | YDR462W | MRPL28 SGDID:S000002870, Chr IV from 1386066-1386509, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 1340 | YDR463W | STP1 SGDID:S000002871, Chr IV from 1386809-1388368, Verified ORF, "Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes and may have a role in tRNA processing" |
| 1341 | YDR464W | SPP41 SGDID:S000002872, Chr IV from 1388865-1393172, Verified ORF, "Protein involved in negative regulation of expression of spliceosome components PRP4 and PRP3" |
| 1342 | YDR465C | RMT2 SGDID:S000002873, Chr IV from 1394567-1393329, reverse complement, Verified ORF, "Arginine methyltransferase; ribosomal protein L12 is a substrate" |
| 1343 | YDR466W | PKH3 SGDID:S000002874, Chr IV from 1395114-1397810, Verified ORF, "Protein kinase with similarity to mammalian phosphoinositide-dependent kinase 1 (PDK1) and yeast Pkh1p and Pkh2p, two redundant upstream activators of Pkc1p; identified as a multicopy suppressor of a pkh1 pkh2 double mutant" |
| 1344 | YDR468C | TLG1 SGDID:S000002876, Chr IV from 1398693-1398019, reverse complement, Verified ORF, "Essential t-SNARE that forms a complex with Tlg2p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds the docking complex VFT (Vps fifty-three) through interaction with Vps51p" |
| 1345 | YDR469W | SDC1 SGDID:S000002877, Chr IV from 1399008-1399535, Verified ORF, "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; has similarity to C. elegans Dpy-30" |
| 1346 | YDR470C | UGO1 SGDID:S000002878, Chr IV from 1401207-1399699, reverse complement, Verified ORF, "Protein of unknown function; outer membrane component of the mitochondrial fusion machinery; Ugo1p bind directly to Fzo1p and Mgm1p and thereby link these two GTPases during mitochondrial fusion" |
| 1347 | YDR471W | RPL27B SGDID:S000002879, Chr IV from 1401763-1401793,1402178-1402557, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Ap and has similarity to rat L27 ribosomal protein" |
| 1348 | YDR472W | TRS31 SGDID:S000002880, Chr IV from 1403315-1404166, Verified ORF, "One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic" |
| 1349 | YDR473C | PRP3 SGDID:S000002881, Chr IV from 1405847-1404438, reverse complement, Verified ORF, "Splicing factor, component of the U4/U6-U5 snRNP complex" |
| 1350 | YDR475C | JIP4 SGDID:S000002883, Chr IV from 1410087-1407457, reverse complement, Verified ORF, "Protein of unknown function; previously annotated as two separate ORFs, YDR474C and YDR475C, which were merged as a result of corrections to the systematic reference sequence" |
| 1351 | YDR476C | YDR476C SGDID:S000002884, Chr IV from 1411120-1410446, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YDR476C is not an essential gene" |
| 1352 | YDR477W | SNF1 SGDID:S000002885, Chr IV from 1412366-1414267, Verified ORF, "AMP-activated serine/threonine protein kinase found in a complex containing Snf4p and members of the Sip1p/Sip2p/Gal83p family; required for transcription of glucose-repressed genes, thermotolerance, sporulation, and peroxisome biogenesis" |
| 1353 | YDR478W | SNM1 SGDID:S000002886, Chr IV from 1414568-1415164, Verified ORF, "Subunit of RNase MRP, which cleaves pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; binds to the NME1 RNA subunit of RNase MRP" |
| 1354 | YDR479C | PEX29 SGDID:S000002887, Chr IV from 1416867-1415203, reverse complement, Verified ORF, "Peroxisomal integral membrane peroxin, involved in the regulation of peroxisomal size, number and distribution; genetic interactions suggest that Pex28p and Pex29p act at steps upstream of those mediated by Pex30p, Pex31p, and Pex32p" |
| 1355 | YDR480W | DIG2 SGDID:S000002888, Chr IV from 1417392-1418363, Verified ORF, "Regulatory protein of unknown function, pheromone-inducible, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription" |
| 1356 | YDR481C | PHO8 SGDID:S000002889, Chr IV from 1420243-1418543, reverse complement, Verified ORF, "Repressible alkaline phosphatase, a glycoprotein localized to the vacuole; regulated by levels of inorganic phosphate and by a system consisting of Pho4p, Pho9p, Pho80p, Pho81p and Pho85p; dephosphorylates phosphotyrosyl peptides" |
| 1357 | YDR482C | CWC21 SGDID:S000002890, Chr IV from 1420831-1420424, reverse complement, Verified ORF, "Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; may bind RNA; has similarity to S. pombe Cwf21p" |
| 1358 | YDR483W | KRE2 SGDID:S000002891, Chr IV from 1421150-1422478, Verified ORF, "Alpha1,2-mannosyltransferase of the Golgi involved in protein mannosylation" |
| 1359 | YDR484W | VPS52 SGDID:S000002892, Chr IV from 1422756-1424681, Verified ORF, "Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; involved in localization of actin and chitin" |
| 1360 | YDR485C | VPS72 SGDID:S000002893, Chr IV from 1427200-1424813, reverse complement, Verified ORF, "Htz1p-binding component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for vacuolar protein sorting" |
| 1361 | YDR486C | VPS60 SGDID:S000002894, Chr IV from 1428113-1427424, reverse complement, Verified ORF, "Cytoplasmic and vacuolar membrane protein involved in late endosome to vacuole transport; required for normal filament maturation during pseudohyphal growth; may function in targeting cargo proteins for degradation; interacts with Vta1p" |
| 1362 | YDR487C | RIB3 SGDID:S000002895, Chr IV from 1428973-1428347, reverse complement, Verified ORF, "3,4-dihydroxy-2-butanone-4-phosphate synthase (DHBP synthase), required for riboflavin biosynthesis from ribulose-5-phosphate, also has an unrelated function in mitochondrial respiration" |
| 1363 | YDR488C | PAC11 SGDID:S000002896, Chr IV from 1430782-1429181, reverse complement, Verified ORF, "Dynein intermediate chain, acts in the cytoplasmic dynein pathway, forms cortical cytoplasmic microtubule capture site with Num1p; null mutant is defective in nuclear migration, essential in the absence of CIN8" |
| 1364 | YDR489W | SLD5 SGDID:S000002897, Chr IV from 1431005-1431889, Verified ORF, "Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery" |
| 1365 | YDR490C | PKH1 SGDID:S000002898, Chr IV from 1434261-1431961, reverse complement, Verified ORF, "Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh2p" |
| 1366 | YDR492W | IZH1 SGDID:S000002900, Chr IV from 1434917-1435867, Verified ORF, "Membrane protein involved in zinc metabolism, member of the four-protein IZH family; transcription is regulated directly by Zap1p, expression induced by zinc deficiency and fatty acids; deletion increases sensitivity to elevated zinc" |
| 1367 | YDR493W | YDR493W SGDID:S000002901, Chr IV from 1436210-1436581, Uncharacterized ORF, "Protein of unknown function; non-tagged protein detected in purified mitochondria in high-throughput studies; null mutant displays decreased frequency of mitochondrial genome loss and severe growth defect in minimal glycerol media" |
| 1368 | YDR494W | RSM28 SGDID:S000002902, Chr IV from 1436923-1438008, Verified ORF, "Mitochondrial ribosomal protein of the small subunit; genetic interactions suggest a possible role in promoting translation initiation" |
| 1369 | YDR495C | VPS3 SGDID:S000002903, Chr IV from 1441143-1438108, reverse complement, Verified ORF, "Component of CORVET tethering complex; cytoplasmic protein required for the sorting and processing of soluble vacuolar proteins, acidification of the vacuolar lumen, and assembly of the vacuolar H+-ATPase" |
| 1370 | YDR496C | PUF6 SGDID:S000002904, Chr IV from 1443396-1441426, reverse complement, Verified ORF, "Pumilio-homology domain protein that binds ASH1 mRNA at PUF consensus sequences in the 3' UTR and represses its translation, resulting in proper asymmetric localization of ASH1 mRNA" |
| 1371 | YDR497C | ITR1 SGDID:S000002905, Chr IV from 1445460-1443706, reverse complement, Verified ORF, "Myo-inositol transporter with strong similarity to the minor myo-inositol transporter Itr2p, member of the sugar transporter superfamily; expression is repressed by inositol and choline via Opi1p and derepressed via Ino2p and Ino4p" |
| 1372 | YDR498C | SEC20 SGDID:S000002906, Chr IV from 1446987-1445836, reverse complement, Verified ORF, "Membrane glycoprotein v-SNARE involved in retrograde transport from the Golgi to the ER; required for N- and O-glycosylation in the Golgi but not in the ER; forms a complex with the cytosolic Tip20p" |
| 1373 | YDR499W | LCD1 SGDID:S000002907, Chr IV from 1447823-1450066, Verified ORF, "Essential protein required for the DNA integrity checkpoint pathways; interacts physically with Mec1p; putative homolog of S. pombe Rad26 and human ATRIP" |
| 1374 | YDR500C | RPL37B SGDID:S000002908, Chr IV from 1450846-1450840,1450450-1450191, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Ap and to rat L37 ribosomal protein" |
| 1375 | YDR501W | PLM2 SGDID:S000002909, Chr IV from 1451346-1452911, Verified ORF, "Protein required for partitioning of the 2-micron plasmid" |
| 1376 | YDR502C | SAM2 SGDID:S000002910, Chr IV from 1454457-1453303, reverse complement, Verified ORF, "S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)" |
| 1377 | YDR503C | LPP1 SGDID:S000002911, Chr IV from 1455859-1455035, reverse complement, Verified ORF, "Lipid phosphate phosphatase, catalyzes Mg(2+)-independent dephosphorylation of phosphatidic acid (PA), lysophosphatidic acid, and diacylglycerol pyrophosphate; involved in control of the cellular levels of phosphatidylinositol and PA" |
| 1378 | YDR504C | SPG3 SGDID:S000002912, Chr IV from 1456687-1456304, reverse complement, Verified ORF, "Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources" |
| 1379 | YDR505C | PSP1 SGDID:S000002913, Chr IV from 1459213-1456688, reverse complement, Verified ORF, "Asn and gln rich protein of unknown function; high-copy suppressor of POL1 (DNA polymerase alpha) and partial suppressor of CDC2 (polymerase delta) and CDC6 (pre-RC loading factor) mutations; overexpression results in growth inhibition" |
| 1380 | YDR506C | YDR506C SGDID:S000002914, Chr IV from 1461547-1459721, reverse complement, Uncharacterized ORF, "Possible membrane-localized protein" |
| 1381 | YDR507C | GIN4 SGDID:S000002915, Chr IV from 1465779-1462351, reverse complement, Verified ORF, "Protein kinase involved in bud growth and assembly of the septin ring, proposed to have kinase-dependent and kinase-independent activities; undergoes autophosphorylation; similar to Kcc4p and Hsl1p" |
| 1382 | YDR508C | GNP1 SGDID:S000002916, Chr IV from 1468437-1466446, reverse complement, Verified ORF, "High-affinity glutamine permease, also transports Leu, Ser, Thr, Cys, Met and Asn; expression is fully dependent on Grr1p and modulated by the Ssy1p-Ptr3p-Ssy5p (SPS) sensor of extracellular amino acids" |
| 1383 | YDR510W | SMT3 SGDID:S000002918, Chr IV from 1469393-1469698, Verified ORF, "Ubiquitin-like protein of the SUMO family, conjugated to lysine residues of target proteins; regulates chromatid cohesion, chromosome segregation, APC-mediated proteolysis, DNA replication and septin ring dynamics" |
| 1384 | YDR511W | ACN9 SGDID:S000002919, Chr IV from 1470010-1470411, Verified ORF, "Protein of the mitochondrial intermembrane space, required for acetate utilization and gluconeogenesis; has orthologs in higher eukaryotes" |
| 1385 | YDR512C | EMI1 SGDID:S000002920, Chr IV from 1471056-1470493, reverse complement, Verified ORF, "Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1, also required for sporulation" |
| 1386 | YDR513W | GRX2 SGDID:S000002921, Chr IV from 1471010-1471441, Verified ORF, "Cytoplasmic glutaredoxin, thioltransferase, glutathione-dependent disulfide oxidoreductase involved in maintaining redox state of target proteins, also exhibits glutathione peroxidase activity, expression induced in response to stress" |
| 1387 | YDR514C | YDR514C SGDID:S000002922, Chr IV from 1472992-1471541, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1388 | YDR515W | SLF1 SGDID:S000002923, Chr IV from 1473422-1474765, Verified ORF, "RNA binding protein that associates with polysomes; proposed to be involved in regulating mRNA translation; involved in the copper-dependent mineralization of copper sulfide complexes on cell surface in cells cultured in copper salts" |
| 1389 | YDR516C | EMI2 SGDID:S000002924, Chr IV from 1476469-1474967, reverse complement, Verified ORF, "Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1; required for sporulation; expression is regulated by glucose-repression transcription factors Mig1/2p" |
| 1390 | YDR517W | GRH1 SGDID:S000002925, Chr IV from 1477232-1478350, Verified ORF, "Acetylated, cis-golgi localized protein involved in ER to Golgi transport; homolog of human GRASP65; forms a complex with the coiled-coil protein Bug1p; mutants are compromised for the fusion of ER-derived vesicles with Golgi membranes" |
| 1391 | YDR518W | EUG1 SGDID:S000002926, Chr IV from 1478601-1480154, Verified ORF, "Protein disulfide isomerase of the endoplasmic reticulum lumen, function overlaps with that of Pdi1p; may interact with nascent polypeptides in the ER" |
| 1392 | YDR519W | FPR2 SGDID:S000002927, Chr IV from 1480418-1480825, Verified ORF, "Membrane-bound peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; expression pattern suggests possible involvement in ER protein trafficking" |
| 1393 | YDR520C | URC2 SGDID:S000002928, Chr IV from 1483396-1481078, reverse complement, Uncharacterized ORF, "Putative transcription factor; contains the (Zn(II)2Cys6 motif; GFP-fusion protein localizes to the cytoplasm and nucleus; null mutant is viable and sensitive to caffeine; similar to the S. Kluyveri URC2 uracil catabolism gene" |
| 1394 | YDR522C | SPS2 SGDID:S000002930, Chr IV from 1485296-1483788, reverse complement, Verified ORF, "Protein expressed during sporulation, redundant with Sps22p for organization of the beta-glucan layer of the spore wall; S. pombe ortholog is a spore wall component" |
| 1395 | YDR523C | SPS1 SGDID:S000002931, Chr IV from 1487031-1485559, reverse complement, Verified ORF, "Putative protein serine/threonine kinase expressed at the end of meiosis and localized to the prospore membrane, required for correct localization of enzymes involved in spore wall synthesis" |
| 1396 | YDR524C | AGE1 SGDID:S000002932, Chr IV from 1488983-1487535, reverse complement, Verified ORF, "ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in the secretory and endocytic pathways; contains C2C2H2 cysteine/histidine motif" |
| 1397 | YDR524C-B | YDR524C-B SGDID:S000028739, Chr IV from 1489791-1489591, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1398 | YDR524W-C | YDR524W-C SGDID:S000028740, Chr IV from 1489396-1489485, Uncharacterized ORF, "Putative protein of unknown function; small ORF identified by SAGE; deletion strains are moderately sensitive to the radiomimetic drug bleomycin" |
| 1399 | YDR525W-A | SNA2 SGDID:S000007236, Chr IV from 1490589-1490828, Verified ORF, "Protein of unknown function, has similarity to Pmp3p, which is involved in cation transport; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 1400 | YDR527W | RBA50 SGDID:S000002935, Chr IV from 1491087-1492406, Verified ORF, "Protein involved in transcription; interacts with RNA polymerase II subunits Rpb2p, Rpb3, and Rpb11p; has similarity to human RPAP1" |
| 1401 | YDR528W | HLR1 SGDID:S000002936, Chr IV from 1494579-1495850, Verified ORF, "Protein involved in regulation of cell wall composition and integrity and response to osmotic stress; overproduction suppresses a lysis sensitive PKC mutation; similar to Lre1p, which functions antagonistically to protein kinase A" |
| 1402 | YDR529C | QCR7 SGDID:S000002937, Chr IV from 1496541-1496158, reverse complement, Verified ORF, "Subunit 7 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the mitochondrial matrix; N-terminus appears to play a role in complex assembly" |
| 1403 | YDR530C | APA2 SGDID:S000002938, Chr IV from 1497761-1496784, reverse complement, Verified ORF, "Diadenosine 5',5''-P1,P4-tetraphosphate phosphorylase II (AP4A phosphorylase), involved in catabolism of bis(5'-nucleosidyl) tetraphosphates; has similarity to Apa1p" |
| 1404 | YDR531W | YDR531W SGDID:S000002939, Chr IV from 1498225-1499328, Uncharacterized ORF, "Pantothenate kinase (ATP:D-pantothenate 4'-phosphotransferase, EC 2.7.1.33); catalyzes the first committed step in the universal biosynthetic pathway leading to coenzyme A1" |
| 1405 | YDR532C | YDR532C SGDID:S000002940, Chr IV from 1500546-1499389, reverse complement, Uncharacterized ORF, "Protein of unknown function that localizes to the nuclear side of the spindle pole body and along short spindles; deletion mutants have short telomeres; forms a complex with Spc105p" |
| 1406 | YDR533C | HSP31 SGDID:S000002941, Chr IV from 1502153-1501440, reverse complement, Verified ORF, "Possible chaperone and cysteine protease with similarity to E. coli Hsp31; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease; exists as a dimer and contains a putative metal-binding site" |
| 1407 | YDR534C | FIT1 SGDID:S000002942, Chr IV from 1504892-1503306, reverse complement, Verified ORF, "Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall" |
| 1408 | YDR536W | STL1 SGDID:S000002944, Chr IV from 1507997-1509706, Verified ORF, "Glycerol proton symporter of the plasma membrane, subject to glucose-induced inactivation, strongly but transiently induced when cells are subjected to osmotic shock" |
| 1409 | YDR538W | PAD1 SGDID:S000002946, Chr IV from 1510893-1511621, Verified ORF, "Phenylacrylic acid decarboxylase, confers resistance to cinnamic acid, decarboxylates aromatic carboxylic acids to the corresponding vinyl derivatives; homolog of E. coli UbiX" |
| 1410 | YDR539W | YDR539W SGDID:S000002947, Chr IV from 1512085-1513596, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YDR539W is not an essential gene; homolog of E. coli UbiD" |
| 1411 | YDR540C | IRC4 SGDID:S000002948, Chr IV from 1517660-1517121, reverse complement, Verified ORF, "Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
| 1412 | YDR541C | YDR541C SGDID:S000002949, Chr IV from 1520683-1519649, reverse complement, Uncharacterized ORF, "Putative dihydrokaempferol 4-reductase" |
| 1413 | YDR542W | YDR542W SGDID:S000002950, Chr IV from 1523235-1523597, Uncharacterized ORF, "Hypothetical protein" |
| 1414 | YDR545W | YRF1-1 SGDID:S000002953, Chr IV from 1526307-1531697, Verified ORF, "Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p" |
| 1415 | YEL001C | IRC22 SGDID:S000000727, Chr V from 150977-150300, reverse complement, Verified ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; YEL001C is non-essential; null mutant displays increased levels of spontaneous Rad52p foci" |
| 1416 | YEL002C | WBP1 SGDID:S000000728, Chr V from 150013-148721, reverse complement, Verified ORF, "Beta subunit of the oligosaccharyl transferase (OST) glycoprotein complex; required for N-linked glycosylation of proteins in the endoplasmic reticulum" |
| 1417 | YEL003W | GIM4 SGDID:S000000729, Chr V from 148175-148193,148282-148598, Verified ORF, "Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it" |
| 1418 | YEL004W | YEA4 SGDID:S000000730, Chr V from 146950-147978, Verified ORF, "Uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) transporter required for cell wall chitin synthesis; localized to the ER" |
| 1419 | YEL005C | VAB2 SGDID:S000000731, Chr V from 146754-145906, reverse complement, Verified ORF, "Protein with a potential role in vacuolar function, as suggested by its ability to bind Vac8p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 1420 | YEL006W | YEA6 SGDID:S000000732, Chr V from 144326-145333, Verified ORF, "Putative mitochondrial NAD+ transporter, member of the mitochondrial carrier subfamily (see also YIA6); has putative human ortholog" |
| 1421 | YEL007W | YEL007W SGDID:S000000733, Chr V from 141891-143891, Uncharacterized ORF, "Putative protein with sequence similarity to S. pombe gti1+ (gluconate transport inducer 1)" |
| 1422 | YEL009C | GCN4 SGDID:S000000735, Chr V from 139763-138918, reverse complement, Verified ORF, "Transcriptional activator of amino acid biosynthetic genes in response to amino acid starvation; expression is tightly regulated at both the transcriptional and translational levels" |
| 1423 | YEL011W | GLC3 SGDID:S000000737, Chr V from 133120-135234, Verified ORF, "Glycogen branching enzyme, involved in glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 1424 | YEL012W | UBC8 SGDID:S000000738, Chr V from 131772-131776,131900-132551, Verified ORF, "Ubiquitin-conjugating enzyme that negatively regulates gluconeogenesis by mediating the glucose-induced ubiquitination of fructose-1,6-bisphosphatase (FBPase); cytoplasmic enzyme that catalyzes the ubiquitination of histones in vitro" |
| 1425 | YEL013W | VAC8 SGDID:S000000739, Chr V from 128825-130561, Verified ORF, "Phosphorylated vacuolar membrane protein that interacts with Atg13p, required for the cytoplasm-to-vacuole targeting (Cvt) pathway; interacts with Nvj1p to form nucleus-vacuole junctions" |
| 1426 | YEL015W | EDC3 SGDID:S000000741, Chr V from 126629-128284, Verified ORF, "Non-essential conserved protein of unknown function, plays a role in mRNA decapping by specifically affecting the function of the decapping enzyme Dcp1p; localizes to cytoplasmic mRNA processing bodies" |
| 1427 | YEL016C | NPP2 SGDID:S000000742, Chr V from 126218-124737, reverse complement, Verified ORF, "Nucleotide pyrophosphatase/phosphodiesterase family member; mediates extracellular nucleotide phosphate hydrolysis along with Npp1p and Pho5p; activity and expression enhanced during conditions of phosphate starvation" |
| 1428 | YEL017C-A | PMP2 SGDID:S000002103, Chr V from 122929-122798, reverse complement, Verified ORF, "Proteolipid associated with plasma membrane H(+)-ATPase (Pma1p); regulates plasma membrane H(+)-ATPase activity; nearly identical to PMP1" |
| 1429 | YEL017W | GTT3 SGDID:S000000743, Chr V from 123657-124670, Verified ORF, "Protein of unknown function with a possible role in glutathione metabolism, as suggested by computational analysis of large-scale protein-protein interaction data; GFP-fusion protein localizes to the nuclear periphery" |
| 1430 | YEL018W | EAF5 SGDID:S000000744, Chr V from 121471-122310, Verified ORF, "Esa1p-associated factor, non-essential subunit of the NuA4 acetyltransferase complex" |
| 1431 | YEL019C | MMS21 SGDID:S000000745, Chr V from 121301-120498, reverse complement, Verified ORF, "SUMO ligase involved in chromosomal organization and DNA repair; essential subunit of the Mms21-Smc5-Smc6 complex; mutants are sensitive to methyl methanesulfonate and show increased spontaneous mutation and mitotic recombination" |
| 1432 | YEL020C | YEL020C SGDID:S000000746, Chr V from 120299-118617, reverse complement, Uncharacterized ORF, "Hypothetical protein with low sequence identity to Pdc1p" |
| 1433 | YEL020W-A | TIM9 SGDID:S000007256, Chr V from 117211-117474, Verified ORF, "Mitochondrial intermembrane space protein, forms a complex with Mrs11p/Tim10p that mediates import and insertion of a subset of polytopic inner membrane proteins; may prevent aggregation of incoming proteins in a chaperone-like manner" |
| 1434 | YEL021W | URA3 SGDID:S000000747, Chr V from 116167-116970, Verified ORF, "Orotidine-5'-phosphate (OMP) decarboxylase, catalyzes the sixth enzymatic step in the de novo biosynthesis of pyrimidines, converting OMP into uridine monophosphate (UMP); converts 5-FOA into 5-fluorouracil, a toxic compound" |
| 1435 | YEL022W | GEA2 SGDID:S000000748, Chr V from 111421-115800, Verified ORF, "Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; similar to but not functionally redundant with Gea1p" |
| 1436 | YEL023C | YEL023C SGDID:S000000749, Chr V from 110552-108504, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; expression is increased greatly during sporulation; YEL023C is not an essential gene" |
| 1437 | YEL024W | RIP1 SGDID:S000000750, Chr V from 107260-107907, Verified ORF, "Ubiquinol-cytochrome-c reductase, a Rieske iron-sulfur protein of the mitochondrial cytochrome bc1 complex; transfers electrons from ubiquinol to cytochrome c1 during respiration" |
| 1438 | YEL025C | YEL025C SGDID:S000000751, Chr V from 106147-102581, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus" |
| 1439 | YEL026W | SNU13 SGDID:S000000752, Chr V from 101943-102323, Verified ORF, "RNA binding protein, part of U3 snoRNP involved in rRNA processing, part of U4/U6-U5 tri-snRNP involved in mRNA splicing, similar to human 15.5K protein" |
| 1440 | YEL027W | CUP5 SGDID:S000000753, Chr V from 100769-101251, Verified ORF, "Proteolipid subunit of the vacuolar H(+)-ATPase V0 sector (subunit c; dicyclohexylcarbodiimide binding subunit); required for vacuolar acidification and important for copper and iron metal ion homeostasis" |
| 1441 | YEL029C | BUD16 SGDID:S000000755, Chr V from 97796-96858, reverse complement, Verified ORF, "Putative pyridoxal kinase, key enzyme in vitamin B6 metabolism; involved in maintaining levels of pyridoxal 5'-phosphate, the active form of vitamin B6; required for genome integrity; homolog of E. coli PdxK; involved in bud-site selection" |
| 1442 | YEL030W | ECM10 SGDID:S000000756, Chr V from 94644-96578, Verified ORF, "Heat shock protein of the Hsp70 family, localized in mitochondrial nucleoids, plays a role in protein translocation, interacts with Mge1p in an ATP-dependent manner; overexpression induces extensive mitochondrial DNA aggregations" |
| 1443 | YEL031W | SPF1 SGDID:S000000757, Chr V from 90258-93905, Verified ORF, "P-type ATPase, ion transporter of the ER membrane involved in ER function and Ca2+ homeostasis; required for regulating Hmg2p degradation; confers sensitivity to a killer toxin (SMKT) produced by Pichia farinosa KK1" |
| 1444 | YEL032W | MCM3 SGDID:S000000758, Chr V from 86937-89852, Verified ORF, "Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex" |
| 1445 | YEL034W | HYP2 SGDID:S000000760, Chr V from 85676-86149, Verified ORF, "Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Anb1p; possible role in translation elongation; undergoes an essential hypusination modification" |
| 1446 | YEL035C | UTR5 SGDID:S000000761, Chr V from 85545-85045, reverse complement, Uncharacterized ORF, "Protein of unknown function; transcription may be regulated by Gcr1p" |
| 1447 | YEL036C | ANP1 SGDID:S000000762, Chr V from 84552-83050, reverse complement, Verified ORF, "Subunit of the alpha-1,6 mannosyltransferase complex; type II membrane protein; has a role in retention of glycosyltransferases in the Golgi; involved in osmotic sensitivity and resistance to aminonitrophenyl propanediol" |
| 1448 | YEL037C | RAD23 SGDID:S000000763, Chr V from 82603-81407, reverse complement, Verified ORF, "Protein with ubiquitin-like N terminus, recognizes and binds damaged DNA (with Rad4p) during nucleotide excision repair; regulates Rad4p levels, subunit of Nuclear Excision Repair Factor 2 (NEF2); homolog of human HR23A and HR23B proteins" |
| 1449 | YEL038W | UTR4 SGDID:S000000764, Chr V from 80462-81145, Verified ORF, "Protein of unknown function with sequence similarity to 2,3-diketo-5-methylthiopentyl-1-phosphate enolase-phosphatases, found in both the cytoplasm and nucleus" |
| 1450 | YEL039C | CYC7 SGDID:S000000765, Chr V from 79977-79636, reverse complement, Verified ORF, "Cytochrome c isoform 2, expressed under hypoxic conditions; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration" |
| 1451 | YEL040W | UTR2 SGDID:S000000766, Chr V from 78053-79456, Verified ORF, "Cell wall protein that functions in the transfer of chitin to beta(1-6)glucan; putative chitin transglycosidase; glycosylphosphatidylinositol (GPI)-anchored protein localized to the bud neck; has a role in cell wall maintenance" |
| 1452 | YEL041W | YEF1 SGDID:S000000767, Chr V from 75944-77431, Verified ORF, "ATP-NADH kinase; phosphorylates both NAD and NADH; homooctameric structure consisting of 60-kDa subunits; sequence similarity to Utr1p and Pos5p; overexpression complements certain pos5 phenotypes" |
| 1453 | YEL042W | GDA1 SGDID:S000000768, Chr V from 73771-75327, Verified ORF, "Guanosine diphosphatase located in the Golgi, involved in the transport of GDP-mannose into the Golgi lumen by converting GDP to GMP after mannose is transferred its substrate" |
| 1454 | YEL043W | YEL043W SGDID:S000000769, Chr V from 70478-73348, Verified ORF, "Predicted cytoskeleton protein involved in intracellular signalling based on quantitative analysis of protein-protein interaction maps; may interact with ribosomes, based on co-purification studies; contains fibronectin type III domain fold" |
| 1455 | YEL044W | IES6 SGDID:S000000770, Chr V from 69757-70257, Verified ORF, "Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions" |
| 1456 | YEL046C | GLY1 SGDID:S000000772, Chr V from 68792-67629, reverse complement, Verified ORF, "Threonine aldolase, catalyzes the cleavage of L-allo-threonine and L-threonine to glycine; involved in glycine biosynthesis" |
| 1457 | YEL047C | YEL047C SGDID:S000000773, Chr V from 66797-65385, reverse complement, Verified ORF, "Soluble fumarate reductase, required with isoenzyme Osm1p for anaerobic growth; may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies" |
| 1458 | YEL048C | YEL048C SGDID:S000000774, Chr V from 65167-64709, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; synthetic lethal with gcs1delta" |
| 1459 | YEL049W | PAU2 SGDID:S000000775, Chr V from 63728-64090, Verified ORF, "Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme" |
| 1460 | YEL050C | RML2 SGDID:S000000776, Chr V from 60851-59670, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit, has similarity to E. coli L2 ribosomal protein; fat21 mutant allele causes inability to utilize oleate and may interfere with activity of the Adr1p transcription factor" |
| 1461 | YEL051W | VMA8 SGDID:S000000777, Chr V from 58378-59148, Verified ORF, "Subunit D of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; plays a role in the coupling of proton transport and ATP hydrolysis" |
| 1462 | YEL052W | AFG1 SGDID:S000000778, Chr V from 56571-58100, Verified ORF, "Conserved protein that may act as a chaperone in the degradation of misfolded or unassembled cytochrome c oxidase subunits; localized to matrix face of the mitochondrial inner membrane; member of the AAA family but lacks a protease domain" |
| 1463 | YEL053C | MAK10 SGDID:S000000779, Chr V from 56102-53901, reverse complement, Verified ORF, "Non-catalytic subunit of N-terminal acetyltransferase of the NatC type, required for replication of dsRNA virus; expression is glucose-repressible" |
| 1464 | YEL054C | RPL12A SGDID:S000000780, Chr V from 53218-52721, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl12Bp; rpl12a rpl12b double mutant exhibits slow growth and slow translation; has similarity to E. coli L11 and rat L12 ribosomal proteins" |
| 1465 | YEL055C | POL5 SGDID:S000000781, Chr V from 51539-48471, reverse complement, Verified ORF, "DNA Polymerase phi; has sequence similarity to the human MybBP1A and weak sequence similarity to B-type DNA polymerases, not required for chromosomal DNA replication; required for the synthesis of rRNA" |
| 1466 | YEL056W | HAT2 SGDID:S000000782, Chr V from 47168-48373, Verified ORF, "Subunit of the Hat1p-Hat2p histone acetyltransferase complex; required for high affinity binding of the complex to free histone H4, thereby enhancing Hat1p activity; similar to human RbAp46 and 48; has a role in telomeric silencing" |
| 1467 | YEL057C | YEL057C SGDID:S000000783, Chr V from 45721-45020, reverse complement, Uncharacterized ORF, "Protein of unknown function involved in telomere maintenance; target of UME6 regulation" |
| 1468 | YEL058W | PCM1 SGDID:S000000784, Chr V from 43252-44925, Verified ORF, "Essential N-acetylglucosamine-phosphate mutase; converts GlcNAc-6-P to GlcNAc-1-P, which is a precursor for the biosynthesis of chitin and for the formation of N-glycosylated mannoproteins and glycosylphosphatidylinositol anchors" |
| 1469 | YEL059C-A | SOM1 SGDID:S000002954, Chr V from 42624-42400, reverse complement, Verified ORF, "Subunit of the mitochondrial inner membrane peptidase, which is required for maturation of mitochondrial proteins of the intermembrane space; Som1p facilitates cleavage of a subset of substrates" |
| 1470 | YEL060C | PRB1 SGDID:S000000786, Chr V from 41953-40046, reverse complement, Verified ORF, "Vacuolar proteinase B (yscB), a serine protease of the subtilisin family; involved in protein degradation in the vacuole and required for full protein degradation during sporulation" |
| 1471 | YEL061C | CIN8 SGDID:S000000787, Chr V from 39537-36535, reverse complement, Verified ORF, "Kinesin motor protein involved in mitotic spindle assembly and chromosome segregation" |
| 1472 | YEL062W | NPR2 SGDID:S000000788, Chr V from 34407-36254, Verified ORF, "Protein with a possible role in regulating expression of nitrogen permeases; transcription is induced in response to proline and urea; contains two PEST sequences; null mutant is resistant to cisplatin and doxorubicin" |
| 1473 | YEL063C | CAN1 SGDID:S000000789, Chr V from 33466-31694, reverse complement, Verified ORF, "Plasma membrane arginine permease, requires phosphatidyl ethanolamine (PE) for localization, exclusively associated with lipid rafts; mutation confers canavanine resistance" |
| 1474 | YEL064C | AVT2 SGDID:S000000790, Chr V from 31239-29797, reverse complement, Verified ORF, "Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" |
| 1475 | YEL065W | SIT1 SGDID:S000000791, Chr V from 27657-29543, Verified ORF, "Ferrioxamine B transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; transcription is induced during iron deprivation and diauxic shift; potentially phosphorylated by Cdc28p" |
| 1476 | YEL066W | HPA3 SGDID:S000000792, Chr V from 26667-27206, Verified ORF, "D-Amino acid N-acetyltransferase, catalyzes N-acetylation of D-amino acids through ordered bi-bi mechanism in which acetyl-CoA is first substrate bound and CoA is last product liberated; similar to Hpa2p, acetylates histones weakly in vitro" |
| 1477 | YEL067C | YEL067C SGDID:S000000793, Chr V from 26776-26189, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 1478 | YEL069C | HXT13 SGDID:S000000795, Chr V from 23231-21537, reverse complement, Verified ORF, "Hexose transporter, induced in the presence of non-fermentable carbon sources, induced by low levels of glucose, repressed by high levels of glucose" |
| 1479 | YEL070W | DSF1 SGDID:S000000796, Chr V from 19589-21097, Uncharacterized ORF, "Deletion suppressor of mpt5 mutation" |
| 1480 | YEL071W | DLD3 SGDID:S000000797, Chr V from 16355-17845, Verified ORF, "D-lactate dehydrogenase, part of the retrograde regulon which consists of genes whose expression is stimulated by damage to mitochondria and reduced in cells grown with glutamate as the sole nitrogen source, located in the cytoplasm" |
| 1481 | YEL072W | RMD6 SGDID:S000000798, Chr V from 13720-14415, Verified ORF, "Protein required for sporulation" |
| 1482 | YEL073C | YEL073C SGDID:S000000799, Chr V from 7553-7230, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; located adjacent to ARS503 and the telomere on the left arm of chromosome V; regulated by inositol/choline" |
| 1483 | YEL075C | YEL075C SGDID:S000000801, Chr V from 5713-5345, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1484 | YEL076C | YEL076C SGDID:S000000802, Chr V from 5114-4464, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1485 | YEL076C-A | YEL076C-A SGDID:S000002955, Chr V from 5114-4602,4322-4185, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1486 | YEL077C | YEL077C SGDID:S000006409, Chr V from 4097-264, reverse complement, Uncharacterized ORF, "Helicase-like protein encoded within the telomeric Y' element" |
| 1487 | YER001W | MNN1 SGDID:S000000803, Chr V from 153519-155807, Verified ORF, "Alpha-1,3-mannosyltransferase, integral membrane glycoprotein of the Golgi complex, required for addition of alpha1,3-mannose linkages to N-linked and O-linked oligosaccharides, one of five S. cerevisiae proteins of the MNN1 family" |
| 1488 | YER002W | NOP16 SGDID:S000000804, Chr V from 156802-157497, Verified ORF, "Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis" |
| 1489 | YER003C | PMI40 SGDID:S000000805, Chr V from 159117-159087,158993-157735, reverse complement, Verified ORF, "Mannose-6-phosphate isomerase, catalyzes the interconversion of fructose-6-P and mannose-6-P; required for early steps in protein mannosylation" |
| 1490 | YER004W | FMP52 SGDID:S000000806, Chr V from 159579-160274, Verified ORF, "Protein of unknown function, localized to the mitochondrial outer membrane; induced by treatment with 8-methoxypsoralen and UVA irradiation" |
| 1491 | YER005W | YND1 SGDID:S000000807, Chr V from 160549-162441, Verified ORF, "Apyrase with wide substrate specificity, involved in preventing the inhibition of glycosylation by hydrolyzing nucleoside tri- and diphosphates which are inhibitors of glycotransferases; partially redundant with Gda1p" |
| 1492 | YER006W | NUG1 SGDID:S000000808, Chr V from 162722-164284, Verified ORF, "GTPase that associates with nuclear 60S pre-ribosomes, required for export of 60S ribosomal subunits from the nucleus" |
| 1493 | YER007C-A | TMA20 SGDID:S000002957, Chr V from 166884-166874,166770-166236, reverse complement, Verified ORF, "Protein of unknown function that associates with ribosomes and has a putative RNA binding domain; interacts with Tma22p; null mutant exhibits translation defects; has homology to human oncogene MCT-1" |
| 1494 | YER007W | PAC2 SGDID:S000000809, Chr V from 164526-166082, Verified ORF, "Microtubule effector required for tubulin heterodimer formation, binds alpha-tubulin, required for normal microtubule function, null mutant exhibits cold-sensitive microtubules and sensitivity to benomyl" |
| 1495 | YER008C | SEC3 SGDID:S000000810, Chr V from 171817-167807, reverse complement, Verified ORF, "Non-essential subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, Exo84p) which mediates targeting of post-Golgi vesicles to sites of active exocytosis; Sec3p specifically is a spatial landmark for secretion" |
| 1496 | YER009W | NTF2 SGDID:S000000811, Chr V from 172114-172491, Verified ORF, "Nuclear envelope protein, interacts with GDP-bound Gsp1p and with proteins of the nuclear pore to transport Gsp1p into the nucleus where it is an essential player in nucleocytoplasmic transport" |
| 1497 | YER010C | YER010C SGDID:S000000812, Chr V from 173337-172633, reverse complement, Verified ORF, "Protein of unknown function, forms a ring-shaped homotrimer; has similarity to members of the prokaryotic rraA family; possibly involved in a phosphotransfer reaction" |
| 1498 | YER011W | TIR1 SGDID:S000000813, Chr V from 175247-176011, Verified ORF, "Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expression is downregulated at acidic pH and induced by cold shock and anaerobiosis; abundance is increased in cells cultured without shaking" |
| 1499 | YER012W | PRE1 SGDID:S000000814, Chr V from 177834-178430, Verified ORF, "Beta 4 subunit of the 20S proteasome; localizes to the nucleus throughout the cell cycle" |
| 1500 | YER013W | PRP22 SGDID:S000000815, Chr V from 178840-182277, Verified ORF, "DEAH-box RNA-dependent ATPase/ATP-dependent RNA helicase, associates with lariat intermediates before the second catalytic step of splicing; mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes" |
| 1501 | YER014C-A | BUD25 SGDID:S000007590, Chr V from 184699-184677,184168-183730, reverse complement, Verified ORF, "Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern" |
| 1502 | YER014W | HEM14 SGDID:S000000816, Chr V from 182599-184218, Verified ORF, "Protoporphyrinogen oxidase, a mitochondrial enzyme that catalyzes the seventh step in the heme biosynthetic pathway, converting protoporphyrinogen IX to protoporphyrin IX" |
| 1503 | YER015W | FAA2 SGDID:S000000817, Chr V from 184540-186774, Verified ORF, "Long chain fatty acyl-CoA synthetase; accepts a wider range of acyl chain lengths than Faa1p, preferring C9:0-C13:0; involved in the activation of endogenous pools of fatty acids" |
| 1504 | YER016W | BIM1 SGDID:S000000818, Chr V from 188276-189310, Verified ORF, "Microtubule-binding protein that together with Kar9p makes up the cortical microtubule capture site and delays the exit from mitosis when the spindle is oriented abnormally" |
| 1505 | YER017C | AFG3 SGDID:S000000819, Chr V from 191787-189502, reverse complement, Verified ORF, "Component, with Yta12p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes" |
| 1506 | YER018C | SPC25 SGDID:S000000820, Chr V from 192623-191958, reverse complement, Verified ORF, "Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering" |
| 1507 | YER019C-A | SBH2 SGDID:S000002127, Chr V from 194538-194272, reverse complement, Verified ORF, "Ssh1p-Sss1p-Sbh2p complex component, involved in protein translocation into the endoplasmic reticulum; homologous to Sbh1p" |
| 1508 | YER019W | ISC1 SGDID:S000000821, Chr V from 192796-194229, Verified ORF, "Mitochondrial membrane localized inositol phosphosphingolipid phospholipase C, hydrolyzes complex sphingolipids to produce ceramide; activated by phosphatidylserine, cardiolipin, and phosphatidylglycerol; mediates Na+ and Li+ halotolerance" |
| 1509 | YER020W | GPA2 SGDID:S000000822, Chr V from 195167-196516, Verified ORF, "Nucleotide binding alpha subunit of the heterotrimeric G protein that interacts with the receptor Gpr1p, has signaling role in response to nutrients; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery" |
| 1510 | YER021W | RPN3 SGDID:S000000823, Chr V from 196947-198518, Verified ORF, "Essential, non-ATPase regulatory subunit of the 26S proteasome lid, similar to the p58 subunit of the human 26S proteasome; temperature-sensitive alleles cause metaphase arrest, suggesting a role for the proteasome in cell cycle control" |
| 1511 | YER022W | SRB4 SGDID:S000000824, Chr V from 198811-200874, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation" |
| 1512 | YER023W | PRO3 SGDID:S000000825, Chr V from 201075-201935, Verified ORF, "Delta 1-pyrroline-5-carboxylate reductase, catalyzes the last step in proline biosynthesis" |
| 1513 | YER024W | YAT2 SGDID:S000000826, Chr V from 202191-204962, Verified ORF, "Carnitine acetyltransferase; has similarity to Yat1p, which is a carnitine acetyltransferase associated with the mitochondrial outer membrane" |
| 1514 | YER025W | GCD11 SGDID:S000000827, Chr V from 205250-206833, Verified ORF, "Gamma subunit of the translation initiation factor eIF2, involved in the identification of the start codon; binds GTP when forming the ternary complex with GTP and tRNAi-Met" |
| 1515 | YER026C | CHO1 SGDID:S000000828, Chr V from 208473-207643, reverse complement, Verified ORF, "Phosphatidylserine synthase, functions in phospholipid biosynthesis; catalyzes the reaction CDP-diaclyglycerol + L-serine = CMP + L-1-phosphatidylserine, transcriptionally repressed by myo-inositol and choline" |
| 1516 | YER027C | GAL83 SGDID:S000000829, Chr V from 210231-208978, reverse complement, Verified ORF, "One of three possible beta-subunits of the Snf1 kinase complex, allows nuclear localization of the Snf1 kinase complex in the presence of a nonfermentable carbon source; contains glycogen-binding domain" |
| 1517 | YER028C | MIG3 SGDID:S000000830, Chr V from 211875-210691, reverse complement, Verified ORF, "Probable transcriptional repressor involved in response to toxic agents such as hydroxyurea that inhibit ribonucleotide reductase; phosphorylation by Snf1p or the Mec1p pathway inactivates Mig3p, allowing induction of damage response genes" |
| 1518 | YER029C | SMB1 SGDID:S000000831, Chr V from 213176-212586, reverse complement, Verified ORF, "Core Sm protein Sm B; part of heteroheptameric complex (with Smd1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm B and Sm B'" |
| 1519 | YER030W | CHZ1 SGDID:S000000832, Chr V from 213436-213897, Verified ORF, "Histone chaperone for Htz1p/H2A-H2B dimer; required for the stabilization of the Chz1p-Htz1-H2B complex; has overlapping function with Nap1p; null mutant displays weak sensitivity to MMS and benomyl; contains a highly conserved CHZ motif" |
| 1520 | YER031C | YPT31 SGDID:S000000833, Chr V from 214746-214075, reverse complement, Verified ORF, "GTPase of the Ypt/Rab family, very similar to Ypt32p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi" |
| 1521 | YER032W | FIR1 SGDID:S000000834, Chr V from 215062-217692, Verified ORF, "Protein involved in 3' mRNA processing, interacts with Ref2p; potential Cdc28p substrate" |
| 1522 | YER033C | ZRG8 SGDID:S000000835, Chr V from 221286-218056, reverse complement, Verified ORF, "Protein of unknown function; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; GFP-fusion protein is localized to the cytoplasm; transcription induced under conditions of zinc deficiency" |
| 1523 | YER034W | YER034W SGDID:S000000836, Chr V from 221845-222402, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene; expression induced upon calcium shortage" |
| 1524 | YER035W | EDC2 SGDID:S000000837, Chr V from 222638-223075, Verified ORF, "RNA-binding protein, activates mRNA decapping directly by binding to the mRNA substrate and enhancing the activity of the decapping proteins Dcp1p and Dcp2p" |
| 1525 | YER036C | ARB1 SGDID:S000000838, Chr V from 225198-223366, reverse complement, Verified ORF, "ATPase of the ATP-binding cassette (ABC) family involved in 40S and 60S ribosome biogenesis, has similarity to Gcn20p; shuttles from nucleus to cytoplasm, physically interacts with Tif6p, Lsg1p" |
| 1526 | YER037W | PHM8 SGDID:S000000839, Chr V from 225888-226853, Verified ORF, "Protein of unknown function, expression is induced by low phosphate levels and by inactivation of Pho85p" |
| 1527 | YER038C | KRE29 SGDID:S000000840, Chr V from 228251-226857, reverse complement, Verified ORF, "Essential subunit of the Mms21-Smc5-Smc6 complex; protein of unknown function; required for growth and DNA repair; heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance" |
| 1528 | YER039C | HVG1 SGDID:S000000841, Chr V from 229204-228455, reverse complement, Verified ORF, "Protein of unknown function, has homology to Vrg4p" |
| 1529 | YER039C-A | YER039C-A SGDID:S000007226, Chr V from 229480-229262, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YER039C-A is not an essential gene" |
| 1530 | YER040W | GLN3 SGDID:S000000842, Chr V from 229794-231986, Verified ORF, "Transcriptional activator of genes regulated by nitrogen catabolite repression (NCR), localization and activity regulated by quality of nitrogen source" |
| 1531 | YER041W | YEN1 SGDID:S000000843, Chr V from 232460-234739, Verified ORF, "Protein of unknown function, has similarity to endonuclease Rth1p; potentially phosphorylated by Cdc28p" |
| 1532 | YER042W | MXR1 SGDID:S000000844, Chr V from 234936-235490, Verified ORF, "Peptide methionine sulfoxide reductase, reverses the oxidation of methionine residues; involved in oxidative damage repair, providing resistance to oxidative stress and regulation of lifespan" |
| 1533 | YER043C | SAH1 SGDID:S000000845, Chr V from 237118-235769, reverse complement, Verified ORF, "S-adenosyl-L-homocysteine hydrolase, catabolizes S-adenosyl-L-homocysteine which is formed after donation of the activated methyl group of S-adenosyl-L-methionine (AdoMet) to an acceptor" |
| 1534 | YER044C | ERG28 SGDID:S000000846, Chr V from 238015-237569, reverse complement, Verified ORF, "Endoplasmic reticulum membrane protein, may facilitate protein-protein interactions between the Erg26p dehydrogenase and the Erg27p 3-ketoreductase and/or tether these enzymes to the ER, also interacts with Erg6p" |
| 1535 | YER044C-A | MEI4 SGDID:S000001954, Chr V from 239773-239711,239622-238459, reverse complement, Verified ORF, "Meiosis-specific protein involved in recombination; required for chromosome synapsis; required for production of viable spores" |
| 1536 | YER045C | ACA1 SGDID:S000000847, Chr V from 241500-240031, reverse complement, Verified ORF, "Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, may regulate transcription of genes involved in utilization of non-optimal carbon sources" |
| 1537 | YER046W | SPO73 SGDID:S000000848, Chr V from 243179-243610, Verified ORF, "Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensible for both nuclear divisions during meiosis" |
| 1538 | YER047C | SAP1 SGDID:S000000849, Chr V from 246502-243809, reverse complement, Verified ORF, "Putative ATPase of the AAA family, interacts with the Sin1p transcriptional repressor in the two-hybrid system" |
| 1539 | YER048C | CAJ1 SGDID:S000000850, Chr V from 248156-246981, reverse complement, Verified ORF, "Nuclear type II J heat shock protein of the E. coli dnaJ family, contains a leucine zipper-like motif, binds to non-native substrates for presentation to Ssa3p, may function during protein translocation, assembly and disassembly" |
| 1540 | YER048W-A | ISD11 SGDID:S000007237, Chr V from 250717-251001, Verified ORF, "Protein required for mitochondrial iron-sulfur cluster biosynthesis" |
| 1541 | YER049W | TPA1 SGDID:S000000851, Chr V from 251727-253661, Verified ORF, "Protein of unknown function; interacts with Sup45p (eRF1), Sup35p (eRF3) and Pab1p; has a role in translation termination efficiency, mRNA poly(A) tail length and mRNA stability" |
| 1542 | YER050C | RSM18 SGDID:S000000852, Chr V from 254386-253970, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S18 ribosomal protein" |
| 1543 | YER051W | JHD1 SGDID:S000000853, Chr V from 254655-256133, Verified ORF, "JmjC domain family histone demethylase specific for H3-K36, similar to proteins found in human, mouse, drosophila, X. laevis, C. elegans, and S. pombe" |
| 1544 | YER052C | HOM3 SGDID:S000000854, Chr V from 257957-256374, reverse complement, Verified ORF, "Aspartate kinase (L-aspartate 4-P-transferase); cytoplasmic enzyme that catalyzes the first step in the common pathway for methionine and threonine biosynthesis; expression regulated by Gcn4p and the general control of amino acid synthesis" |
| 1545 | YER053C | PIC2 SGDID:S000000855, Chr V from 259638-258736, reverse complement, Verified ORF, "Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Mir1p but less abundant than Mir1p under normal conditions; expression is induced at high temperature" |
| 1546 | YER053C-A | YER053C-A SGDID:S000007523, Chr V from 261045-260932, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum" |
| 1547 | YER054C | GIP2 SGDID:S000000856, Chr V from 263697-262051, reverse complement, Verified ORF, "Putative regulatory subunit of the protein phosphatase Glc7p, involved in glycogen metabolism; contains a conserved motif (GVNK motif) that is also found in Gac1p, Pig1p, and Pig2p" |
| 1548 | YER055C | HIS1 SGDID:S000000857, Chr V from 265784-264891, reverse complement, Verified ORF, "ATP phosphoribosyltransferase, a hexameric enzyme, catalyzes the first step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control" |
| 1549 | YER056C | FCY2 SGDID:S000000858, Chr V from 268112-266511, reverse complement, Verified ORF, "Purine-cytosine permease, mediates purine (adenine, guanine, and hypoxanthine) and cytosine accumulation" |
| 1550 | YER056C-A | RPL34A SGDID:S000002135, Chr V from 270183-270147,269749-269421, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Bp and has similarity to rat L34 ribosomal protein" |
| 1551 | YER057C | HMF1 SGDID:S000000859, Chr V from 271124-270735, reverse complement, Verified ORF, "Member of the p14.5 protein family with similarity to Mmf1p, functionally complements Mmf1p function when targeted to mitochondria; heat shock inducible; high-dosage growth inhibitor; forms a homotrimer in vitro" |
| 1552 | YER058W | PET117 SGDID:S000000860, Chr V from 271766-272089, Verified ORF, "Protein required for assembly of cytochrome c oxidase" |
| 1553 | YER059W | PCL6 SGDID:S000000861, Chr V from 272622-273884, Verified ORF, "Pho85p cyclin of the Pho80p subfamily; forms the major Glc8p kinase together with Pcl7p and Pho85p; involved in the control of glycogen storage by Pho85p; stabilized by Elongin C binding" |
| 1554 | YER060W | FCY21 SGDID:S000000862, Chr V from 274565-276151, Verified ORF, "Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function" |
| 1555 | YER060W-A | FCY22 SGDID:S000002958, Chr V from 276570-278162, Verified ORF, "Putative purine-cytosine permease, very similar to Fcy2p but cannot substitute for its function" |
| 1556 | YER061C | CEM1 SGDID:S000000863, Chr V from 279624-278296, reverse complement, Verified ORF, "Mitochondrial beta-keto-acyl synthase with possible role in fatty acid synthesis; required for mitochondrial respiration" |
| 1557 | YER062C | HOR2 SGDID:S000000864, Chr V from 280680-279928, reverse complement, Verified ORF, "One of two redundant DL-glycerol-3-phosphatases (RHR2/GPP1 encodes the other) involved in glycerol biosynthesis; induced in response to hyperosmotic stress and oxidative stress, and during the diauxic transition" |
| 1558 | YER063W | THO1 SGDID:S000000865, Chr V from 281708-282364, Verified ORF, "Conserved nuclear RNA-binding protein; specifically binds to transcribed chromatin in a THO- and RNA-dependent manner, genetically interacts with shuttling hnRNP NAB2; overproduction suppresses transcriptional defect caused by hpr1 mutation" |
| 1559 | YER064C | YER064C SGDID:S000000866, Chr V from 284220-282703, reverse complement, Uncharacterized ORF, "Non-essential nuclear protein; null mutation has global effects on transcription" |
| 1560 | YER065C | ICL1 SGDID:S000000867, Chr V from 286912-285239, reverse complement, Verified ORF, "Isocitrate lyase, catalyzes the formation of succinate and glyoxylate from isocitrate, a key reaction of the glyoxylate cycle; expression of ICL1 is induced by growth on ethanol and repressed by growth on glucose" |
| 1561 | YER066W | YER066W SGDID:S000000868, Chr V from 290240-290797, Uncharacterized ORF, "Putative protein of unknown function; YER066W is not an essential gene" |
| 1562 | YER067W | YER067W SGDID:S000000869, Chr V from 292064-292549, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YER067W is not an essential gene" |
| 1563 | YER068W | MOT2 SGDID:S000000870, Chr V from 293048-294811, Verified ORF, "Component of the CCR4-NOT complex, which has multiple roles in transcription regulation, mRNA degradation, and post-transcriptional modifications; with Ubc4p, ubiquitylates subunits of the nascent polypeptide-associated complex (NAC)" |
| 1564 | YER069W | ARG5,6 SGDID:S000000871, Chr V from 295408-297999, Verified ORF, "Protein that is processed in the mitochondrion to yield acetylglutamate kinase and N-acetyl-gamma-glutamyl-phosphate reductase, which catalyze the 2nd and 3rd steps in arginine biosynthesis; enzymes form a complex with Arg2p" |
| 1565 | YER070W | RNR1 SGDID:S000000872, Chr V from 298948-301614, Verified ORF, "One of two large regulatory subunits of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits" |
| 1566 | YER071C | YER071C SGDID:S000000873, Chr V from 302325-301945, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 1567 | YER072W | VTC1 SGDID:S000000874, Chr V from 302804-303193, Verified ORF, "Vacuolar transporter chaperon (VTC) involved in distributing V-ATPase and other membrane proteins; together with other VTC proteins, forms a heterotetrameric complex that associates with the SNARE Nyv1p and the V0 sector of the V-ATPase" |
| 1568 | YER073W | ALD5 SGDID:S000000875, Chr V from 304027-305589, Verified ORF, "Mitochondrial aldehyde dehydrogenase, involved in regulation or biosynthesis of electron transport chain components and acetate formation; activated by K+; utilizes NADP+ as the preferred coenzyme; constitutively expressed" |
| 1569 | YER074W | RPS24A SGDID:S000000876, Chr V from 306319-306321,306788-307192, Verified ORF, "Protein component of the small (40S) ribosomal subunit; identical to Rps24Bp and has similarity to rat S24 ribosomal protein" |
| 1570 | YER074W-A | YOS1 SGDID:S000007651, Chr V from 307649-307742,307845-307952,308064-308119, Verified ORF, "Integral membrane protein required for ER to Golgi transport; localized to the Golgi, the ER, and COPII vesicles; interacts with Yip1p and Yif1p" |
| 1571 | YER075C | PTP3 SGDID:S000000877, Chr V from 311195-308409, reverse complement, Verified ORF, "Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the cytoplasm" |
| 1572 | YER076C | YER076C SGDID:S000000878, Chr V from 313494-312586, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; analysis of HA-tagged protein suggests a membrane localization" |
| 1573 | YER077C | YER077C SGDID:S000000879, Chr V from 316596-314530, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion" |
| 1574 | YER078C | YER078C SGDID:S000000880, Chr V from 318338-316803, reverse complement, Uncharacterized ORF, "Putative mitochondrial metallopeptidase" |
| 1575 | YER078W-A | YER078W-A SGDID:S000028546, Chr V from 318642-318806, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 1576 | YER079W | YER079W SGDID:S000000881, Chr V from 318916-319548, Uncharacterized ORF, "Putative protein of unknown function" |
| 1577 | YER080W | YER080W SGDID:S000000882, Chr V from 319959-321842, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays decreased frequency of mitochondrial genome loss (petite formation)" |
| 1578 | YER081W | SER3 SGDID:S000000883, Chr V from 322682-324091, Verified ORF, "3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser33p" |
| 1579 | YER082C | UTP7 SGDID:S000000884, Chr V from 325932-324268, reverse complement, Verified ORF, "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" |
| 1580 | YER083C | GET2 SGDID:S000000885, Chr V from 327027-326170, reverse complement, Verified ORF, "Subunit of the GET complex; required for meiotic nuclear division and for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion; may be involved in cell wall function" |
| 1581 | YER085C | YER085C SGDID:S000000887, Chr V from 328136-327615, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1582 | YER086W | ILV1 SGDID:S000000888, Chr V from 328473-330203, Verified ORF, "Threonine deaminase, catalyzes the first step in isoleucine biosynthesis; expression is under general amino acid control; ILV1 locus exhibits highly positioned nucleosomes whose organization is independent of known ILV1 regulation" |
| 1583 | YER087C-B | SBH1 SGDID:S000002128, Chr V from 332826-332578, reverse complement, Verified ORF, "Beta subunit of the Sec61p ER translocation complex (Sec61p-Sss1p-Sbh1p); involved in protein translocation into the endoplasmic reticulum; interacts with the exocyst complex and also with Rtn1p; homologous to Sbh2p" |
| 1584 | YER087W | YER087W SGDID:S000000889, Chr V from 330572-332302, Uncharacterized ORF, "Protein with similarity to tRNA synthetases; non-tagged protein is detected in purified mitochondria; null mutant displays decreased frequency of mitochondrial genome loss (petite formation), severe growth defect in minimal glycerol media" |
| 1585 | YER088C | DOT6 SGDID:S000000890, Chr V from 335184-333172, reverse complement, Verified ORF, "Protein of unknown function, involved in telomeric gene silencing and filamentation" |
| 1586 | YER089C | PTC2 SGDID:S000000891, Chr V from 337336-335942, reverse complement, Verified ORF, "Type 2C protein phosphatase; dephosphorylates Hog1p to limit maximal osmostress induced kinase activity; dephosphorylates Ire1p to downregulate the unfolded protein response; dephosphorylates Cdc28p; role in DNA checkpoint inactivation" |
| 1587 | YER090W | TRP2 SGDID:S000000892, Chr V from 337945-339468, Verified ORF, "Anthranilate synthase, catalyzes the initial step of tryptophan biosynthesis, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp3p" |
| 1588 | YER091C | MET6 SGDID:S000000893, Chr V from 342163-339860, reverse complement, Verified ORF, "Cobalamin-independent methionine synthase, involved in amino acid biosynthesis; requires a minimum of two glutamates on the methyltetrahydrofolate substrate, similar to bacterial metE homologs" |
| 1589 | YER092W | IES5 SGDID:S000000894, Chr V from 342851-343228, Verified ORF, "Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions" |
| 1590 | YER093C | TSC11 SGDID:S000000895, Chr V from 347608-343316, reverse complement, Verified ORF, "Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p), a membrane-associated complex that regulates actin cytoskeletal dynamics during polarized growth and cell wall integrity; involved in sphingolipid metabolism; contains a RasGEFN domain" |
| 1591 | YER093C-A | YER093C-A SGDID:S000002960, Chr V from 348396-348273,348197-347908, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YER093C-A contains an intron; null mutant displays increased frequency of mitochondrial genome loss (petite formation)" |
| 1592 | YER094C | PUP3 SGDID:S000000896, Chr V from 349342-348725, reverse complement, Verified ORF, "Beta 3 subunit of the 20S proteasome involved in ubiquitin-dependent catabolism; human homolog is subunit C10" |
| 1593 | YER095W | RAD51 SGDID:S000000897, Chr V from 349976-351178, Verified ORF, "Strand exchange protein, forms a helical filament with DNA that searches for homology; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; homolog of Dmc1p and bacterial RecA protein" |
| 1594 | YER096W | SHC1 SGDID:S000000898, Chr V from 351694-353232, Verified ORF, "Sporulation-specific activator of Chs3p (chitin synthase III), required for the synthesis of the chitosan layer of ascospores; has similarity to Skt5p, which activates Chs3p during vegetative growth; transcriptionally induced at alkaline pH" |
| 1595 | YER098W | UBP9 SGDID:S000000900, Chr V from 355462-357726, Verified ORF, "Ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease that cleaves ubiquitin-protein fusions" |
| 1596 | YER099C | PRS2 SGDID:S000000901, Chr V from 359057-358101, reverse complement, Verified ORF, "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes" |
| 1597 | YER100W | UBC6 SGDID:S000000902, Chr V from 359558-360310, Verified ORF, "Ubiquitin-conjugating enzyme involved in ER-associated protein degradation; located at the cytosolic side of the ER membrane; tail region contains a transmembrane segment at the C-terminus; substrate of the ubiquitin-proteasome pathway" |
| 1598 | YER101C | AST2 SGDID:S000000903, Chr V from 361790-360498, reverse complement, Verified ORF, "Protein that may have a role in targeting of plasma membrane [H+]ATPase (Pma1p) to the plasma membrane, as suggested by analysis of genetic interactions" |
| 1599 | YER102W | RPS8B SGDID:S000000904, Chr V from 363096-363698, Verified ORF, "Protein component of the small (40S) ribosomal subunit; identical to Rps8Ap and has similarity to rat S8 ribosomal protein" |
| 1600 | YER103W | SSA4 SGDID:S000000905, Chr V from 364585-366513, Verified ORF, "Heat shock protein that is highly induced upon stress; plays a role in SRP-dependent cotranslational protein-membrane targeting and translocation; member of the HSP70 family; cytoplasmic protein that concentrates in nuclei upon starvation" |
| 1601 | YER104W | RTT105 SGDID:S000000906, Chr V from 366798-367424, Verified ORF, "Protein with a role in regulation of Ty1 transposition" |
| 1602 | YER105C | NUP157 SGDID:S000000907, Chr V from 372009-367834, reverse complement, Verified ORF, "Abundant subunit of the nuclear pore complex (NPC), present on both sides of the NPC, has similarity to Nup170p" |
| 1603 | YER106W | MAM1 SGDID:S000000908, Chr V from 372322-373230, Verified ORF, "Monopolin, kinetochore associated protein involved in chromosome attachment to meiotic spindle" |
| 1604 | YER107C | GLE2 SGDID:S000000909, Chr V from 374541-373444, reverse complement, Verified ORF, "Component of the nuclear pore complex required for polyadenylated RNA export but not for protein import, homologous to S. pombe Rae1p" |
| 1605 | YER109C | FLO8 SGDID:S000000911, Chr V from 377610-375211, reverse complement, Verified ORF, "Transcription factor required for flocculation, diploid filamentous growth, and haploid invasive growth; genome reference strain S288C and most laboratory strains have a mutation in this gene" |
| 1606 | YER110C | KAP123 SGDID:S000000912, Chr V from 382099-378758, reverse complement, Verified ORF, "Karyopherin beta, mediates nuclear import of ribosomal proteins prior to assembly into ribosomes and import of histones H3 and H4; localizes to the nuclear pore, nucleus, and cytoplasm; exhibits genetic interactions with RAI1" |
| 1607 | YER111C | SWI4 SGDID:S000000913, Chr V from 385872-382591, reverse complement, Verified ORF, "DNA binding component of the SBF complex (Swi4p-Swi6p), a transcriptional activator that in concert with MBF (Mbp1-Swi6p) regulates late G1-specific transcription of targets including cyclins and genes required for DNA synthesis and repair" |
| 1608 | YER112W | LSM4 SGDID:S000000914, Chr V from 387228-387791, Verified ORF, "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" |
| 1609 | YER113C | TMN3 SGDID:S000000915, Chr V from 390048-387928, reverse complement, Verified ORF, "Protein with a role in cellular adhesion and filamentous growth; similar to Emp70p and Tmn2p; member of Transmembrane Nine family with 9 transmembrane segments; localizes to Golgi; induced by 8-methoxypsoralen plus UVA irradiation" |
| 1610 | YER114C | BOI2 SGDID:S000000916, Chr V from 393708-390586, reverse complement, Verified ORF, "Protein implicated in polar growth, functionally redundant with Boi1p; interacts with bud-emergence protein Bem1p; contains an SH3 (src homology 3) domain and a PH (pleckstrin homology) domain" |
| 1611 | YER115C | SPR6 SGDID:S000000917, Chr V from 394863-394288, reverse complement, Verified ORF, "Protein of unknown function, expressed during sporulation; not required for sporulation, but gene exhibits genetic interactions with other genes required for sporulation" |
| 1612 | YER116C | SLX8 SGDID:S000000918, Chr V from 396168-395344, reverse complement, Verified ORF, "Subunit of the Slx5-Slx8 substrate-specific ubiquitin ligase complex; stimulated by prior attachment of SUMO to the substrate" |
| 1613 | YER117W | RPL23B SGDID:S000000919, Chr V from 396765-396806,397278-397649, Verified ORF, "Protein component of the large (60S) ribosomal subunit, identical to Rpl23Ap and has similarity to E. coli L14 and rat L23 ribosomal proteins" |
| 1614 | YER118C | SHO1 SGDID:S000000920, Chr V from 399051-397948, reverse complement, Verified ORF, "Transmembrane osmosensor, participates in activation of both the Cdc42p- and MAP kinase-dependent filamentous growth pathway and the high-osmolarity glycerol response pathway" |
| 1615 | YER119C | AVT6 SGDID:S000000921, Chr V from 400838-399492, reverse complement, Verified ORF, "Vacuolar amino acid transporter, exports aspartate and glutamate from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" |
| 1616 | YER120W | SCS2 SGDID:S000000922, Chr V from 401131-401865, Verified ORF, "Integral ER membrane protein that regulates phospholipid metabolism via an interaction with the FFAT motif of Opi1p, also involved in telomeric silencing, disruption causes inositol auxotrophy above 34 degrees C, VAP homolog" |
| 1617 | YER121W | YER121W SGDID:S000000923, Chr V from 402371-402715, Uncharacterized ORF, "Putative protein of unknown function; may be involved in phosphatase regulation and/or generation of precursor metabolites and energy" |
| 1618 | YER122C | GLO3 SGDID:S000000924, Chr V from 404348-402867, reverse complement, Verified ORF, "ADP-ribosylation factor GTPase activating protein (ARF GAP), involved in ER-Golgi transport; shares functional similarity with Gcs1p" |
| 1619 | YER123W | YCK3 SGDID:S000000925, Chr V from 404809-406383, Verified ORF, "Palmitoylated, vacuolar membrane-localized casein kinase I isoform; negatively regulates vacuole fusion during hypertonic stress via phosphorylation of the HOPS complex subunit, Vps41p; shares overlapping essential functions with Hrr25p" |
| 1620 | YER124C | DSE1 SGDID:S000000926, Chr V from 409059-407338, reverse complement, Verified ORF, "Daughter cell-specific protein, may participate in pathways regulating cell wall metabolism; deletion affects cell separation after division and sensitivity to drugs targeted against the cell wall" |
| 1621 | YER125W | RSP5 SGDID:S000000927, Chr V from 410185-412614, Verified ORF, "Ubiquitin-protein ligase involved in ubiquitin-mediated protein degradation; functions in multivesicular body sorting, heat shock response and ubiquitylation of arrested RNAPII; contains a hect (homologous to E6-AP carboxyl terminus) domain" |
| 1622 | YER126C | NSA2 SGDID:S000000928, Chr V from 414175-413390, reverse complement, Verified ORF, "Protein constituent of 66S pre-ribosomal particles, contributes to processing of the 27S pre-rRNA" |
| 1623 | YER127W | LCP5 SGDID:S000000929, Chr V from 414477-415550, Verified ORF, "Essential protein involved in maturation of 18S rRNA; depletion leads to inhibited pre-rRNA processing and reduced polysome levels; localizes primarily to the nucleolus" |
| 1624 | YER128W | YER128W SGDID:S000000930, Chr V from 415855-416466, Uncharacterized ORF, "Putative protein of unknown function" |
| 1625 | YER129W | SAK1 SGDID:S000000931, Chr V from 417277-420705, Verified ORF, "Upstream serine/threonine kinase for the SNF1 complex; partially redundant with Elm1p and Tos3p; members of this family have functional orthology with LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome" |
| 1626 | YER130C | YER130C SGDID:S000000932, Chr V from 422442-421111, reverse complement, Uncharacterized ORF, "Hypothetical protein" |
| 1627 | YER131W | RPS26B SGDID:S000000933, Chr V from 423948-424307, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Ap and has similarity to rat S26 ribosomal protein" |
| 1628 | YER132C | PMD1 SGDID:S000000934, Chr V from 430445-425184, reverse complement, Verified ORF, "Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expression; required, with Mds3p, for growth under alkaline conditions" |
| 1629 | YER133W | GLC7 SGDID:S000000935, Chr V from 432491-432667,433193-433954, Verified ORF, "Catalytic subunit of type 1 serine/threonine protein phosphatase, involved in many processes including glycogen metabolism, sporulation, and mitosis; interacts with multiple regulatory subunits; predominantly isolated with Sds22p" |
| 1630 | YER134C | YER134C SGDID:S000000936, Chr V from 437799-437263, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene" |
| 1631 | YER136W | GDI1 SGDID:S000000938, Chr V from 439612-440967, Verified ORF, "GDP dissociation inhibitor, regulates vesicle traffic in secretory pathways by regulating the dissociation of GDP from the Sec4/Ypt/rab family of GTP binding proteins" |
| 1632 | YER137C | YER137C SGDID:S000000939, Chr V from 441815-441369, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1633 | YER137C-A | YER137C-A SGDID:S000007402, Chr V from 449020-447698, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 1634 | YER138C | YER138C SGDID:S000000940, Chr V from 449020-447719,447717-443752, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 1635 | YER138W-A | YER138W-A SGDID:S000007239, Chr V from 449470-449574, Uncharacterized ORF, "Putative protein of unknown function" |
| 1636 | YER139C | RTR1 SGDID:S000000941, Chr V from 451238-450558, reverse complement, Verified ORF, "Protein with a role in transcription; interacts with Rpo21p; has a cysteine-rich motif required for function and conserved in eukaryotes; shuttles between the nucleus and cytoplasm; RTR1 shows genetic interactions with RPB4, 5, 7, and 9" |
| 1637 | YER140W | YER140W SGDID:S000000942, Chr V from 451560-453230, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 1638 | YER141W | COX15 SGDID:S000000943, Chr V from 453454-454914, Verified ORF, "Protein required for the hydroxylation of heme O to form heme A, which is an essential prosthetic group for cytochrome c oxidase" |
| 1639 | YER142C | MAG1 SGDID:S000000944, Chr V from 456031-455141, reverse complement, Verified ORF, "3-methyl-adenine DNA glycosylase involved in protecting DNA against alkylating agents; initiates base excision repair by removing damaged bases to create abasic sites that are subsequently repaired" |
| 1640 | YER143W | DDI1 SGDID:S000000945, Chr V from 456314-457600, Verified ORF, "DNA damage-inducible v-SNARE binding protein, contains a ubiquitin-associated (UBA) domain, may act as a negative regulator of constitutive exocytosis, may play a role in S-phase checkpoint control" |
| 1641 | YER144C | UBP5 SGDID:S000000946, Chr V from 460218-457801, reverse complement, Verified ORF, "Putative ubiquitin-specific protease, closest paralog of Doa4p but has no functional overlap; concentrates at the bud neck" |
| 1642 | YER145C | FTR1 SGDID:S000000947, Chr V from 461735-460521, reverse complement, Verified ORF, "High affinity iron permease involved in the transport of iron across the plasma membrane; forms complex with Fet3p; expression is regulated by iron" |
| 1643 | YER146W | LSM5 SGDID:S000000948, Chr V from 462580-462861, Verified ORF, "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" |
| 1644 | YER147C | SCC4 SGDID:S000000949, Chr V from 464837-462963, reverse complement, Verified ORF, "Subunit of cohesin loading factor (Scc2p-Scc4p), a complex required for the loading of cohesin complexes onto chromosomes; involved in establishing sister chromatid cohesion during double-strand break repair via phosphorylated histone H2AX" |
| 1645 | YER148W | SPT15 SGDID:S000000950, Chr V from 465298-466020, Verified ORF, "TATA-binding protein, general transcription factor that interacts with other factors to form the preinitiation complex at promoters, essential for viability" |
| 1646 | YER149C | PEA2 SGDID:S000000951, Chr V from 467465-466203, reverse complement, Verified ORF, "Coiled-coil polarisome protein required for polarized morphogenesis, cell fusion, and low affinity Ca2+ influx; forms polarisome complex with Bni1p, Bud6p, and Spa2p; localizes to sites of polarized growth" |
| 1647 | YER150W | SPI1 SGDID:S000000952, Chr V from 468365-468811, Verified ORF, "GPI-anchored cell wall protein involved in weak acid resistance; basal expression requires Msn2p/Msn4p; expression is induced under conditions of stress and during the diauxic shift; similar to Sed1p" |
| 1648 | YER151C | UBP3 SGDID:S000000953, Chr V from 472419-469681, reverse complement, Verified ORF, "Ubiquitin-specific protease that interacts with Bre5p to co-regulate anterograde and retrograde transport between endoplasmic reticulum and Golgi compartments; inhibitor of gene silencing; cleaves ubiquitin fusions but not polyubiquitin" |
| 1649 | YER152C | YER152C SGDID:S000000954, Chr V from 473983-472652, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; shares amino acid similarity with the aminotransferases Aro8p and Aro9p; YER152C is not an essential gene" |
| 1650 | YER153C | PET122 SGDID:S000000955, Chr V from 474800-474036, reverse complement, Verified ORF, "Mitochondrial translational activator specific for the COX3 mRNA, acts together with Pet54p and Pet494p; located in the mitochondrial inner membrane" |
| 1651 | YER154W | OXA1 SGDID:S000000956, Chr V from 475015-476223, Verified ORF, "Mitochondrial inner membrane insertase, mediates the insertion of both mitochondrial- and nuclear-encoded proteins from the matrix into the inner membrane, interacts with mitochondrial ribosomes; conserved from bacteria to animals" |
| 1652 | YER155C | BEM2 SGDID:S000000957, Chr V from 482843-476340, reverse complement, Verified ORF, "Rho GTPase activating protein (RhoGAP) involved in the control of cytoskeleton organization and cellular morphogenesis; required for bud emergence" |
| 1653 | YER156C | YER156C SGDID:S000000958, Chr V from 484336-483320, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
| 1654 | YER157W | COG3 SGDID:S000000959, Chr V from 484783-487188, Verified ORF, "Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" |
| 1655 | YER158C | YER158C SGDID:S000000960, Chr V from 490573-488852, reverse complement, Uncharacterized ORF, "Protein of unknown function, has similarity to Afr1p; potentially phosphorylated by Cdc28p" |
| 1656 | YER159C | BUR6 SGDID:S000000961, Chr V from 491953-491525, reverse complement, Verified ORF, "Subunit of a heterodimeric NC2 transcription regulator complex with Ncb2p; complex binds to TBP and can repress transcription by preventing preinitiation complex assembly or stimulate activated transcription; homologous to human NC2alpha" |
| 1657 | YER159C-A | YER159C-A SGDID:S000007403, Chr V from 498119-496797, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 1658 | YER160C | YER160C SGDID:S000000962, Chr V from 498119-496818,496816-492851, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 1659 | YER161C | SPT2 SGDID:S000000963, Chr V from 500343-499342, reverse complement, Verified ORF, "Protein involved in negative regulation of transcription; required for RNA polyadenylation; exhibits regulated interactions with both histones and SWI-SNF components, has similarity to mammalian HMG1 proteins" |
| 1660 | YER162C | RAD4 SGDID:S000000964, Chr V from 502889-500625, reverse complement, Verified ORF, "Protein that recognizes and binds damaged DNA (with Rad23p) during nucleotide excision repair; subunit of Nuclear Excision Repair Factor 2 (NEF2); homolog of human XPC protein" |
| 1661 | YER163C | YER163C SGDID:S000000965, Chr V from 503777-503079, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
| 1662 | YER164W | CHD1 SGDID:S000000966, Chr V from 505387-509793, Verified ORF, "Nucleosome remodeling factor that functions in regulation of transcription elongation; contains a chromo domain, a helicase domain and a DNA-binding domain; component of both the SAGA and SLIK complexes" |
| 1663 | YER165W | PAB1 SGDID:S000000967, Chr V from 510368-512101, Verified ORF, "Poly(A) binding protein, part of the 3'-end RNA-processing complex, mediates interactions between the 5' cap structure and the 3' mRNA poly(A) tail, involved in control of poly(A) tail length, interacts with translation factor eIF-4G" |
| 1664 | YER166W | DNF1 SGDID:S000000968, Chr V from 512739-517454, Verified ORF, "Aminophospholipid translocase (flippase) that localizes primarily to the plasma membrane; contributes to endocytosis, protein transport and cell polarity; type 4 P-type ATPase" |
| 1665 | YER167W | BCK2 SGDID:S000000969, Chr V from 518211-520766, Verified ORF, "Protein rich in serine and threonine residues involved in protein kinase C signaling pathway, which controls cell integrity; overproduction suppresses pkc1 mutations" |
| 1666 | YER168C | CCA1 SGDID:S000000970, Chr V from 522664-521024, reverse complement, Verified ORF, "ATP (CTP):tRNA-specific tRNA nucleotidyltransferase; different forms targeted to the nucleus, cytosol, and mitochondrion are generated via the use of multiple transcriptional and translational start sites" |
| 1667 | YER169W | RPH1 SGDID:S000000971, Chr V from 523364-525754, Verified ORF, "JmjC domain-containing histone demethylase which can specifically demethylate H3K36 tri- and dimethyl modification states; transcriptional repressor of PHR1; Rph1p phosphorylation during DNA damage is under control of the MEC1-RAD53 pathway" |
| 1668 | YER170W | ADK2 SGDID:S000000972, Chr V from 525969-526646, Verified ORF, "Mitochondrial adenylate kinase, catalyzes the reversible synthesis of GTP and AMP from GDP and ADP; may serve as a back-up for synthesizing GTP or ADP depending on metabolic conditions; 3' sequence of ADK2 varies with strain background" |
| 1669 | YER171W | RAD3 SGDID:S000000973, Chr V from 527077-529413, Verified ORF, "5' to 3' DNA helicase, involved in nucleotide excision repair and transcription; subunit of RNA polymerase II transcription initiation factor TFIIH; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPD protein" |
| 1670 | YER172C | BRR2 SGDID:S000000974, Chr V from 536016-529525, reverse complement, Verified ORF, "RNA-dependent ATPase RNA helicase (DEIH box); required for disruption of U4/U6 base-pairing in native snRNPs to activate the spliceosome for catalysis; homologous to human U5-200kD" |
| 1671 | YER173W | RAD24 SGDID:S000000975, Chr V from 536295-538274, Verified ORF, "Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; subunit of a clamp loader that loads Rad17p-Mec3p-Ddc1p onto DNA; homolog of human and S. pombe Rad17 protein" |
| 1672 | YER174C | GRX4 SGDID:S000000976, Chr V from 539163-538429, reverse complement, Verified ORF, "Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; monothiol glutaredoxin subfamily member along with Grx3p and Grx5p; protects cells from oxidative damage" |
| 1673 | YER175C | TMT1 SGDID:S000000977, Chr V from 540358-539459, reverse complement, Verified ORF, "Trans-aconitate methyltransferase, cytosolic enzyme that catalyzes the methyl esterification of 3-isopropylmalate, an intermediate of the leucine biosynthetic pathway, and trans-aconitate, which inhibits the citric acid cycle" |
| 1674 | YER175W-A | YER175W-A SGDID:S000028625, Chr V from 540645-540809, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 1675 | YER176W | ECM32 SGDID:S000000978, Chr V from 541685-545050, Verified ORF, "DNA dependent ATPase/DNA helicase belonging to the Dna2p- and Nam7p-like family of helicases that is involved in modulating translation termination; interacts with the translation termination factors, localized to polysomes" |
| 1676 | YER177W | BMH1 SGDID:S000000979, Chr V from 545606-546409, Verified ORF, "14-3-3 protein, major isoform; controls proteome at post-transcriptional level, binds proteins and DNA, involved in regulation of many processes including exocytosis, vesicle transport, Ras/MAPK signaling, and rapamycin-sensitive signaling" |
| 1677 | YER178W | PDA1 SGDID:S000000980, Chr V from 546812-548074, Verified ORF, "E1 alpha subunit of the pyruvate dehydrogenase (PDH) complex, catalyzes the direct oxidative decarboxylation of pyruvate to acetyl-CoA; phosphorylated; regulated by glucose" |
| 1678 | YER179W | DMC1 SGDID:S000000981, Chr V from 548416-548547,548640-549512, Verified ORF, "Meiosis-specific protein required for repair of double-strand breaks and pairing between homologous chromosomes; homolog of Rad51p and the bacterial RecA protein" |
| 1679 | YER180C | ISC10 SGDID:S000000982, Chr V from 550522-549719, reverse complement, Verified ORF, "Protein required for sporulation, transcript is induced 7.5 hours after induction of meiosis, expected to play significant role in the formation of reproductive cells" |
| 1680 | YER180C-A | SLO1 SGDID:S000028437, Chr V from 551117-550860, reverse complement, Verified ORF, "Protein interacting with Arl3p, which is a GTPase of the Ras superfamily involved in vesicle-tethering at the Golgi; putative ortholog of human SCOCO" |
| 1681 | YER182W | YER182W SGDID:S000000984, Chr V from 552520-553254, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 1682 | YER183C | FAU1 SGDID:S000000985, Chr V from 553964-553329, reverse complement, Verified ORF, "5,10-methenyltetrahydrofolate synthetase, involved in folic acid biosynthesis" |
| 1683 | YER184C | YER184C SGDID:S000000986, Chr V from 558675-556291, reverse complement, Uncharacterized ORF, "Putative zinc cluster protein; deletion confers sensitivity to Calcufluor white, and prevents growth on glycerol or lactate as sole carbon source" |
| 1684 | YER185W | PUG1 SGDID:S000000987, Chr V from 559449-560360, Verified ORF, "Plasma membrane protein with roles in the uptake of protoprophyrin IX and the efflux of heme; expression is induced under both low-heme and low-oxygen conditions" |
| 1685 | YER186C | YER186C SGDID:S000000988, Chr V from 562620-561700, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1686 | YER187W | YER187W SGDID:S000000989, Chr V from 566225-566650, Uncharacterized ORF, "Putative protein of unknown function; induced in respiratory-deficient cells" |
| 1687 | YER188C-A | YER188C-A SGDID:S000028764, Chr V from 569902-569603, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1688 | YER189W | YER189W SGDID:S000000991, Chr V from 571150-571518, Uncharacterized ORF, "Putative protein of unknown function" |
| 1689 | YER190C-B | YER190C-B SGDID:S000028627, Chr V from 576157-575675, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 1690 | YER190W | YRF1-2 SGDID:S000000992, Chr V from 571475-576520, Verified ORF, "Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p; induced by treatment with 8-methoxypsoralen and UVA irradiation" |
| 1691 | YFL001W | DEG1 SGDID:S000001895, Chr VI from 147126-148454, Verified ORF, "Non-essential tRNA:pseudouridine synthase, introduces pseudouridines at position 38 or 39 in tRNA, important for maintenance of translation efficiency and normal cell growth, localizes to both the nucleus and cytoplasm" |
| 1692 | YFL002C | SPB4 SGDID:S000001894, Chr VI from 146929-145109, reverse complement, Verified ORF, "Putative ATP-dependent RNA helicase, nucleolar protein required for synthesis of 60S ribosomal subunits at a late step in the pathway; sediments with 66S pre-ribosomes in sucrose gradients" |
| 1693 | YFL002W-A | YFL002W-A SGDID:S000002962, Chr VI from 138199-139491,139493-143512, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 1694 | YFL002W-B | YFL002W-B SGDID:S000007404, Chr VI from 138199-139515, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 1695 | YFL003C | MSH4 SGDID:S000001891, Chr VI from 137152-134516, reverse complement, Verified ORF, "Protein involved in meiotic recombination, required for normal levels of crossing over, colocalizes with Zip2p to discrete foci on meiotic chromosomes, has homology to bacterial MutS protein" |
| 1696 | YFL004W | VTC2 SGDID:S000001890, Chr VI from 131805-134291, Verified ORF, "Vacuolar membrane protein involved in vacuolar polyphosphate accumulation; functions as a regulator of vacuolar H+-ATPase activity and vacuolar transporter chaperones; involved in protein localization and non-autophagic vacuolar fusion" |
| 1697 | YFL005W | SEC4 SGDID:S000001889, Chr VI from 130329-130976, Verified ORF, "Secretory vesicle-associated Rab GTPase essential for exocytosis; associates with the exocyst component Sec15p and may regulate polarized delivery of transport vesicles to the exocyst at the plasma membrane" |
| 1698 | YFL007W | BLM10 SGDID:S000001887, Chr VI from 123474-129905, Verified ORF, "Proteosome activator subunit; found in association with core particles, with and without the 19S regulatory particle; required for resistance to bleomycin, may be involved in protecting against oxidative damage; similar to mammalian PA200" |
| 1699 | YFL008W | SMC1 SGDID:S000001886, Chr VI from 119424-123101, Verified ORF, "Subunit of the multiprotein cohesin complex, essential protein involved in chromosome segregation and in double-strand DNA break repair; SMC chromosomal ATPase family member, binds DNA with a preference for DNA with secondary structure" |
| 1700 | YFL009W | CDC4 SGDID:S000001885, Chr VI from 116139-118478, Verified ORF, "F-box protein required for G1/S and G2/M transition, associates with Skp1p and Cdc53p to form a complex, SCFCdc4, which acts as ubiquitin-protein ligase directing ubiquitination of the phosphorylated CDK inhibitor Sic1p" |
| 1701 | YFL010C | WWM1 SGDID:S000001884, Chr VI from 115737-115102, reverse complement, Verified ORF, "WW domain containing protein of unknown function; binds to Mca1p, a caspase-related protease that regulates H2O2-induced apoptosis; overexpression causes Gi phase growth arrest and clonal death that is suppressed by overexpression of MCA1" |
| 1702 | YFL010W-A | AUA1 SGDID:S000001955, Chr VI from 114984-115268, Verified ORF, "Protein required for the negative regulation by ammonia of Gap1p, which is a general amino acid permease" |
| 1703 | YFL011W | HXT10 SGDID:S000001883, Chr VI from 112339-113979, Verified ORF, "Putative hexose transporter, expressed at low levels and expression is repressed by glucose" |
| 1704 | YFL012W | YFL012W SGDID:S000001882, Chr VI from 110641-111087, Uncharacterized ORF, "Putative protein of unknown function; transcribed during sporulation; null mutant exhibits increased resistance to rapamycin" |
| 1705 | YFL013C | IES1 SGDID:S000001881, Chr VI from 109924-107846, reverse complement, Verified ORF, "Subunit of the INO80 chromatin remodeling complex" |
| 1706 | YFL014W | HSP12 SGDID:S000001880, Chr VI from 107250-107579, Verified ORF, "Plasma membrane localized protein that protects membranes from desiccation; induced by heat shock, oxidative stress, osmostress, stationary phase entry, glucose depletion, oleate and alcohol; regulated by the HOG and Ras-Pka pathways" |
| 1707 | YFL016C | MDJ1 SGDID:S000001878, Chr VI from 106230-104695, reverse complement, Verified ORF, "Co-chaperone that stimulates the ATPase activity of the HSP70 protein Ssc1p; involved in protein folding/refolding in the mitochodrial matrix; required for proteolysis of misfolded proteins; member of the HSP40 (DnaJ) family of chaperones" |
| 1708 | YFL017C | GNA1 SGDID:S000001877, Chr VI from 104456-103977, reverse complement, Verified ORF, "Evolutionarily conserved glucosamine-6-phosphate acetyltransferase required for multiple cell cycle events including passage through START, DNA synthesis, and mitosis; involved in UDP-N-acetylglucosamine synthesis, forms GlcNAc6P from AcCoA" |
| 1709 | YFL017W-A | SMX2 SGDID:S000002965, Chr VI from 103693-103926, Verified ORF, "Core Sm protein Sm G; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx3p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm G" |
| 1710 | YFL018C | LPD1 SGDID:S000001876, Chr VI from 103121-101622, reverse complement, Verified ORF, "Dihydrolipoamide dehydrogenase, the lipoamide dehydrogenase component (E3) of the pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase multi-enzyme complexes" |
| 1711 | YFL020C | PAU5 SGDID:S000001874, Chr VI from 99593-99225, reverse complement, Verified ORF, "Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme" |
| 1712 | YFL021W | GAT1 SGDID:S000001873, Chr VI from 95964-97496, Verified ORF, "Transcriptional activator of genes involved in nitrogen catabolite repression; contains a GATA-1-type zinc finger DNA-binding motif; activity and localization regulated by nitrogen limitation and Ure2p" |
| 1713 | YFL022C | FRS2 SGDID:S000001872, Chr VI from 95008-93497, reverse complement, Verified ORF, "Alpha subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs1p to form active enzyme; evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase based on protein sequence, but substrate binding is similar" |
| 1714 | YFL023W | BUD27 SGDID:S000001871, Chr VI from 90984-93374, Verified ORF, "Protein involved in bud-site selection, nutrient signaling, and gene expression controlled by TOR kinase; diploid mutants show a random budding pattern rather than the wild-type bipolar pattern; plays a role in regulating Ty1 transposition" |
| 1715 | YFL024C | EPL1 SGDID:S000001870, Chr VI from 90343-87845, reverse complement, Verified ORF, "Component of NuA4, which is an essential histone H4/H2A acetyltransferase complex; homologous to Drosophila Enhancer of Polycomb" |
| 1716 | YFL025C | BST1 SGDID:S000001869, Chr VI from 87232-84143, reverse complement, Verified ORF, "GPI inositol deacylase of the ER that negatively regulates COPII vesicle formation, prevents production of vesicles with defective subunits, required for proper discrimination between resident ER proteins and Golgi-bound cargo molecules" |
| 1717 | YFL026W | STE2 SGDID:S000001868, Chr VI from 82578-83873, Verified ORF, "Receptor for alpha-factor pheromone; seven transmembrane-domain GPCR that interacts with both pheromone and a heterotrimeric G protein to initiate the signaling response that leads to mating between haploid a and alpha cells" |
| 1718 | YFL027C | GYP8 SGDID:S000001867, Chr VI from 81910-80417, reverse complement, Verified ORF, "GTPase-activating protein for yeast Rab family members; Ypt1p is the preferred in vitro substrate but also acts on Sec4p, Ypt31p and Ypt32p; involved in the regulation of ER to Golgi vesicle transport" |
| 1719 | YFL028C | CAF16 SGDID:S000001866, Chr VI from 80211-79342, reverse complement, Verified ORF, "Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation; putative ABC ATPase; interacts with Ssn2p, Ssn3p, and Ssn8p" |
| 1720 | YFL029C | CAK1 SGDID:S000001865, Chr VI from 79159-78053, reverse complement, Verified ORF, "Cyclin-dependent kinase-activating kinase required for passage through the cell cycle, phosphorylates and activates Cdc28p; nucleotide-binding pocket differs significantly from those of most other protein kinases" |
| 1721 | YFL030W | AGX1 SGDID:S000001864, Chr VI from 76829-77986, Verified ORF, "Alanine:glyoxylate aminotransferase (AGT), catalyzes the synthesis of glycine from glyoxylate, which is one of three pathways for glycine biosynthesis in yeast; has similarity to mammalian and plant alanine:glyoxylate aminotransferases" |
| 1722 | YFL031W | HAC1 SGDID:S000001863, Chr VI from 75177-75837,76090-76145, Verified ORF, "bZIP transcription factor (ATF/CREB1 homolog) that regulates the unfolded protein response, via UPRE binding, and membrane biogenesis; ER stress-induced splicing pathway utilizing Ire1p, Trl1p and Ada5p facilitates efficient Hac1p synthesis" |
| 1723 | YFL033C | RIM15 SGDID:S000001861, Chr VI from 74425-69113, reverse complement, Verified ORF, "Glucose-repressible protein kinase involved in signal transduction during cell proliferation in response to nutrients, specifically the establishment of stationary phase; identified as a regulator of IME2; substrate of Pho80p-Pho85p kinase" |
| 1724 | YFL034C-A | RPL22B SGDID:S000006436, Chr VI from 64931-64920,64598-64242, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22Ap and to rat L22 ribosomal protein" |
| 1725 | YFL034C-B | MOB2 SGDID:S000001859, Chr VI from 63992-63973,63858-63015, reverse complement, Verified ORF, "Component of the RAM signaling network, localizes and activates the Ace2p in the daughter cell nucleus to direct daughter cell-specific transcription of several genes involved in cell separation; Mob1p-like protein" |
| 1726 | YFL034W | YFL034W SGDID:S000001860, Chr VI from 65475-68696, Uncharacterized ORF, "Putative integral membrane protein that interacts with Rpp0p, which is a component of the ribosomal stalk" |
| 1727 | YFL036W | RPO41 SGDID:S000001858, Chr VI from 58781-62836, Verified ORF, "Mitochondrial RNA polymerase; single subunit enzyme similar to those of T3 and T7 bacteriophages; requires a specificity subunit encoded by MTF1 for promoter recognition" |
| 1728 | YFL037W | TUB2 SGDID:S000001857, Chr VI from 56335-57708, Verified ORF, "Beta-tubulin; associates with alpha-tubulin (Tub1p and Tub3p) to form tubulin dimer, which polymerizes to form microtubules" |
| 1729 | YFL038C | YPT1 SGDID:S000001856, Chr VI from 55985-55365, reverse complement, Verified ORF, "Ras-like small GTPase, involved in the ER-to-Golgi step of the secretory pathway; complex formation with the Rab escort protein Mrs6p is required for prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)" |
| 1730 | YFL039C | ACT1 SGDID:S000001855, Chr VI from 54695-54686,54377-53260, reverse complement, Verified ORF, "Actin, structural protein involved in cell polarization, endocytosis, and other cytoskeletal functions" |
| 1731 | YFL040W | YFL040W SGDID:S000001854, Chr VI from 51350-52972, Uncharacterized ORF, "Putative transporter, member of the sugar porter family; YFL040W is not an essential gene" |
| 1732 | YFL041W | FET5 SGDID:S000001853, Chr VI from 49139-51007, Verified ORF, "Multicopper oxidase, integral membrane protein with similarity to Fet3p; may have a role in iron transport" |
| 1733 | YFL041W-A | YFL041W-A SGDID:S000028547, Chr VI from 48734-48925, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 1734 | YFL042C | YFL042C SGDID:S000001852, Chr VI from 47744-45720, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YFL042C is not an essential gene" |
| 1735 | YFL044C | OTU1 SGDID:S000001850, Chr VI from 45560-44655, reverse complement, Verified ORF, "Deubiquitylation enzyme that binds to the chaperone-ATPase Cdc48p; may contribute to regulation of protein degradation by deubiquitylating substrates that have been ubiquitylated by Ufd2p; member of the Ovarian Tumor (OTU) family" |
| 1736 | YFL045C | SEC53 SGDID:S000001849, Chr VI from 44392-43628, reverse complement, Verified ORF, "Phosphomannomutase, involved in synthesis of GDP-mannose and dolichol-phosphate-mannose; required for folding and glycosylation of secretory proteins in the ER lumen" |
| 1737 | YFL046W | YFL046W SGDID:S000001848, Chr VI from 42815-43438, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 1738 | YFL047W | RGD2 SGDID:S000001847, Chr VI from 40421-42565, Verified ORF, "GTPase-activating protein (RhoGAP) for Cdc42p and Rho5p" |
| 1739 | YFL048C | EMP47 SGDID:S000001846, Chr VI from 40180-38843, reverse complement, Verified ORF, "Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport" |
| 1740 | YFL049W | SWP82 SGDID:S000001845, Chr VI from 36803-38674, Verified ORF, "Member of the SWI/SNF chromatin remodeling complex in which it plays an as yet unidentified role; has identifiable counterparts in closely related yeast species; abundantly expressed in many growth conditions; paralog of Npl6p" |
| 1741 | YFL050C | ALR2 SGDID:S000001844, Chr VI from 35848-33272, reverse complement, Verified ORF, "Probable Mg(2+) transporter; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions; plays a role in regulating Ty1 transposition" |
| 1742 | YFL051C | YFL051C SGDID:S000001843, Chr VI from 30540-30058, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YFL051C is not an essential gene" |
| 1743 | YFL052W | YFL052W SGDID:S000001842, Chr VI from 28232-29629, Uncharacterized ORF, "Putative zinc cluster protein that contains a DNA binding domain; null mutant sensitive to calcofluor white, low osmolarity and heat, suggesting a role for YFL052Wp in cell wall integrity" |
| 1744 | YFL053W | DAK2 SGDID:S000001841, Chr VI from 23423-25198, Verified ORF, "Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation" |
| 1745 | YFL054C | YFL054C SGDID:S000001840, Chr VI from 22787-20847, reverse complement, Uncharacterized ORF, "Putative channel-like protein; similar to Fps1p; mediates passive diffusion of glycerol in the presence of ethanol" |
| 1746 | YFL055W | AGP3 SGDID:S000001839, Chr VI from 17004-18680, Verified ORF, "Low-affinity amino acid permease, may act to supply the cell with amino acids as nitrogen source in nitrogen-poor conditions; transcription is induced under conditions of sulfur limitation; plays a role in regulating Ty1 transposition" |
| 1747 | YFL056C | AAD6 SGDID:S000001838, Chr VI from 15431-14793, reverse complement, Verified ORF, "Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase, involved in the oxidative stress response" |
| 1748 | YFL057C | AAD16 SGDID:S000001837, Chr VI from 14763-14305, reverse complement, Verified ORF, "Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role" |
| 1749 | YFL058W | THI5 SGDID:S000001836, Chr VI from 12929-13951, Verified ORF, "Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13" |
| 1750 | YFL059W | SNZ3 SGDID:S000001835, Chr VI from 11363-12259, Verified ORF, "Member of a stationary phase-induced gene family; transcription of SNZ2 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO3" |
| 1751 | YFL060C | SNO3 SGDID:S000001834, Chr VI from 10969-10301, reverse complement, Verified ORF, "Protein of unknown function, nearly identical to Sno2p; expression is induced before the diauxic shift and also in the absence of thiamin" |
| 1752 | YFL061W | YFL061W SGDID:S000001833, Chr VI from 9545-10222, Uncharacterized ORF, "Protein whose expression is induced by DNA damage" |
| 1753 | YFL062W | COS4 SGDID:S000001832, Chr VI from 6426-7565, Verified ORF, "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" |
| 1754 | YFL064C | YFL064C SGDID:S000001830, Chr VI from 3846-3322, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1755 | YFL065C | YFL065C SGDID:S000001829, Chr VI from 3338-3030, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation" |
| 1756 | YFL066C | YFL066C SGDID:S000001828, Chr VI from 2615-1437, reverse complement, Uncharacterized ORF, "Helicase-like protein encoded within the telomeric Y' element; induced by treatment with 8-methoxypsoralen and UVA irradiation" |
| 1757 | YFL067W | YFL067W SGDID:S000001827, Chr VI from 836-1363, Uncharacterized ORF, "Protein of unknown function, down-regulated at low calcium levels" |
| 1758 | YFL068W | YFL068W SGDID:S000001826, Chr VI from 53-535, Uncharacterized ORF, "Putative protein of unknown function" |
| 1759 | YFR001W | LOC1 SGDID:S000001897, Chr VI from 149105-149719, Verified ORF, "Nuclear protein involved in asymmetric localization of ASH1 mRNA; binds double-stranded RNA in vitro; constituent of 66S pre-ribosomal particles" |
| 1760 | YFR002W | NIC96 SGDID:S000001898, Chr VI from 150011-152530, Verified ORF, "Component of the nuclear pore complex, required for nuclear pore formation; forms a subcomplex with Nsp1p, Nup57p, and Nup49p" |
| 1761 | YFR003C | YPI1 SGDID:S000001899, Chr VI from 153119-152652, reverse complement, Verified ORF, "Inhibitor of the type I protein phosphatase Glc7p, which is involved in regulation of a variety of metabolic processes; overproduction causes decreased cellular content of glycogen" |
| 1762 | YFR004W | RPN11 SGDID:S000001900, Chr VI from 153388-154308, Verified ORF, "Metalloprotease subunit of the 19S regulatory particle of the 26S proteasome lid; couples the deubiquitination and degradation of proteasome substrates" |
| 1763 | YFR005C | SAD1 SGDID:S000001901, Chr VI from 155868-154522, reverse complement, Verified ORF, "Conserved zinc-finger domain protein involved in pre-mRNA splicing, required for assembly of U4 snRNA into the U4/U6 particle" |
| 1764 | YFR006W | YFR006W SGDID:S000001902, Chr VI from 156139-157746, Uncharacterized ORF, "Putative X-Pro aminopeptidase; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YFR006W is not an essential gene" |
| 1765 | YFR007W | YFH7 SGDID:S000001903, Chr VI from 159293-160354, Verified ORF, "Putative kinase with similarity to the phosphoribulokinase/uridine kinase/bacterial pantothenate kinase (PRK/URK/PANK) subfamily of P-loop kinases; null mutant displays decreased frequency of mitochondrial genome loss (petite formation)" |
| 1766 | YFR008W | FAR7 SGDID:S000001904, Chr VI from 160529-161194, Verified ORF, "Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far8p, Far9p, Far10p, and Far11p" |
| 1767 | YFR009W | GCN20 SGDID:S000001905, Chr VI from 162482-164740, Verified ORF, "Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn1p; proposed to stimulate Gcn2p activation by an uncharged tRNA" |
| 1768 | YFR010W | UBP6 SGDID:S000001906, Chr VI from 165060-166559, Verified ORF, "Ubiquitin-specific protease situated in the base subcomplex of the 26S proteasome, releases free ubiquitin from branched polyubiquitin chains; works in opposition to polyubiquitin elongation activity of Hul5p" |
| 1769 | YFR011C | YFR011C SGDID:S000001907, Chr VI from 167251-166739, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; non-tagged protein is detected in highly purified mitochondria; null mutant displays increased frequency of mitochondrial genome loss (petite formation) and reduced growth rate in minimal glycerol media" |
| 1770 | YFR012W | YFR012W SGDID:S000001908, Chr VI from 167881-168489, Uncharacterized ORF, "Putative protein of unknown function" |
| 1771 | YFR012W-A | YFR012W-A SGDID:S000007606, Chr VI from 169216-169302, Uncharacterized ORF, "Putative protein of unknown function; identified by homology" |
| 1772 | YFR013W | IOC3 SGDID:S000001909, Chr VI from 169914-172277, Verified ORF, "Member of a complex (Isw1a) with Isw1p that has nucleosome-stimulated ATPase activity and represses transcription initiation by specific positioning of a promoter proximal dinucleosome; has homology to Esc8p, which is involved in silencing" |
| 1773 | YFR014C | CMK1 SGDID:S000001910, Chr VI from 173869-172529, reverse complement, Verified ORF, "Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to Cmk2p and mammalian Cam Kinase II" |
| 1774 | YFR015C | GSY1 SGDID:S000001911, Chr VI from 176383-174257, reverse complement, Verified ORF, "Glycogen synthase with similarity to Gsy2p, the more highly expressed yeast homolog; expression induced by glucose limitation, nitrogen starvation, environmental stress, and entry into stationary phase" |
| 1775 | YFR016C | YFR016C SGDID:S000001912, Chr VI from 180735-177034, reverse complement, Verified ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and bud; interacts with Spa2p; YFL016C is not an essential gene" |
| 1776 | YFR017C | YFR017C SGDID:S000001913, Chr VI from 182849-182262, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YFR017C is not an essential gene" |
| 1777 | YFR018C | YFR018C SGDID:S000001914, Chr VI from 184210-183119, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1778 | YFR019W | FAB1 SGDID:S000001915, Chr VI from 184490-191326, Verified ORF, "1-phosphatidylinositol-3-phosphate 5-kinase; vacuolar membrane kinase that generates phosphatidylinositol (3,5)P2, which is involved in vacuolar sorting and homeostasis" |
| 1779 | YFR021W | ATG18 SGDID:S000001917, Chr VI from 194800-196302, Verified ORF, "Phosphoinositide binding protein required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; binds both phosphatidylinositol (3,5)-bisphosphate and phosphatidylinositol 3-phosphate; WD-40 repeat protein" |
| 1780 | YFR022W | ROG3 SGDID:S000001918, Chr VI from 196821-199022, Verified ORF, "Protein that binds to Rsp5p, which is a hect-type ubiquitin ligase, via its 2 PY motifs; has similarity to Rod1p; mutation suppresses the temperature sensitivity of an mck1 rim11 double mutant" |
| 1781 | YFR023W | PES4 SGDID:S000001919, Chr VI from 199862-201697, Verified ORF, "Poly(A) binding protein, suppressor of DNA polymerase epsilon mutation, similar to Mip6p" |
| 1782 | YFR024C-A | LSB3 SGDID:S000002968, Chr VI from 203421-203375,203280-201948, reverse complement, Verified ORF, "Protein containing a C-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization" |
| 1783 | YFR025C | HIS2 SGDID:S000001921, Chr VI from 204738-203731, reverse complement, Verified ORF, "Histidinolphosphatase, catalyzes the eighth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control" |
| 1784 | YFR026C | YFR026C SGDID:S000001922, Chr VI from 206245-205736, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1785 | YFR027W | ECO1 SGDID:S000001923, Chr VI from 207440-208285, Verified ORF, "Acetyltransferase required for the establishment of sister chromatid cohesion during DNA replication and in response to double-strand breaks; also required for postreplicative double-strand break repair" |
| 1786 | YFR028C | CDC14 SGDID:S000001924, Chr VI from 210056-208401, reverse complement, Verified ORF, "Protein phosphatase required for mitotic exit; located in the nucleolus until liberated by the FEAR and Mitotic Exit Network in anaphase, enabling it to act on key substrates to effect a decrease in CDK/B-cyclin activity and mitotic exit" |
| 1787 | YFR029W | PTR3 SGDID:S000001925, Chr VI from 210925-212961, Verified ORF, "Component of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that result in regulation of expression of amino acid permease genes" |
| 1788 | YFR030W | MET10 SGDID:S000001926, Chr VI from 213300-216407, Verified ORF, "Subunit alpha of assimilatory sulfite reductase, which is responsible for the conversion of sulfite into sulfide" |
| 1789 | YFR031C | SMC2 SGDID:S000001927, Chr VI from 220094-216582, reverse complement, Verified ORF, "Component of the condensin complex, essential SMC chromosomal ATPase family member that forms a complex with Smc4p to form the active ATPase; Smc2p/Smc4p complex binds DNA, possibly in the cleft formed by the coiled-coil of the folded dimer" |
| 1790 | YFR031C-A | RPL2A SGDID:S000002104, Chr VI from 221406-221403,221255-220495, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, identical to Rpl2Bp and has similarity to E. coli L2 and rat L8 ribosomal proteins" |
| 1791 | YFR032C | YFR032C SGDID:S000001928, Chr VI from 222947-222078, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; transcribed during sporulation; YFR032C is not an essential gene" |
| 1792 | YFR032C-A | RPL29 SGDID:S000006437, Chr VI from 223425-223246, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, has similarity to rat L29 ribosomal protein; not essential for translation, but required for proper joining of the large and small ribosomal subunits and for normal translation rate" |
| 1793 | YFR032C-B | YFR032C-B SGDID:S000028630, Chr VI from 223961-223698, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 1794 | YFR033C | QCR6 SGDID:S000001929, Chr VI from 224757-224314, reverse complement, Verified ORF, "Subunit 6 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; highly acidic protein; required for maturation of cytochrome c1" |
| 1795 | YFR034C | PHO4 SGDID:S000001930, Chr VI from 225946-225008, reverse complement, Verified ORF, "Basic helix-loop-helix (bHLH) transcription factor of the myc-family; binds cooperatively with Pho2p to the PHO5 promoter; function is regulated by phosphorylation at multiple sites and by phosphate availability" |
| 1796 | YFR035C | YFR035C SGDID:S000001931, Chr VI from 226453-226109, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, deletion mutant exhibits synthetic phenotype with alpha-synuclein" |
| 1797 | YFR036W | CDC26 SGDID:S000001932, Chr VI from 226950-227324, Verified ORF, "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" |
| 1798 | YFR037C | RSC8 SGDID:S000001933, Chr VI from 229173-227500, reverse complement, Verified ORF, "Component of the RSC chromatin remodeling complex; essential for viability and mitotic growth; homolog of SWI/SNF subunit Swi3p, but unlike Swi3p, does not activate transcription of reporters" |
| 1799 | YFR038W | IRC5 SGDID:S000001934, Chr VI from 229367-231928, Verified ORF, "Putative ATPase containing the DEAD/H helicase-related sequence motif; null mutant displays increased levels of spontaneous Rad52p foci" |
| 1800 | YFR039C | YFR039C SGDID:S000001935, Chr VI from 233531-231999, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; may be involved in response to high salt and changes in carbon source" |
| 1801 | YFR040W | SAP155 SGDID:S000001936, Chr VI from 234229-237237, Verified ORF, "Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap185p, and Sap190p" |
| 1802 | YFR041C | ERJ5 SGDID:S000001937, Chr VI from 238242-237355, reverse complement, Verified ORF, "Type I membrane protein with a J domain is required to preserve the folding capacity of the endoplasmic reticulum; loss of the non-essential ERJ5 gene leads to a constitutively induced unfolded protein response" |
| 1803 | YFR042W | KEG1 SGDID:S000001938, Chr VI from 238445-239047, Uncharacterized ORF, "Integral membrane protein of the ER; physically interacts with Kre6p; has a role in the synthesis of beta-1,6-glucan in the cell wall; required for cell viability" |
| 1804 | YFR043C | IRC6 SGDID:S000001939, Chr VI from 239814-239101, reverse complement, Verified ORF, "Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci" |
| 1805 | YFR044C | DUG1 SGDID:S000001940, Chr VI from 241424-239979, reverse complement, Verified ORF, "Probable di- and tri-peptidase; forms a complex with Dug2p and Dug3p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)" |
| 1806 | YFR045W | YFR045W SGDID:S000001941, Chr VI from 241985-241996,242069-242986, Uncharacterized ORF, "Putative mitochondrial transport protein; null mutant is viable, exhibits decreased levels of chitin and normal resistance to calcofluor white" |
| 1807 | YFR046C | CNN1 SGDID:S000001942, Chr VI from 244146-243061, reverse complement, Verified ORF, "Kinetochore protein of unknown function; associated with the essential kinetochore proteins Nnf1p and Spc24p; phosphorylated by both Clb5-Cdk1 and, to a lesser extent, Clb2-Cdk1." |
| 1808 | YFR047C | BNA6 SGDID:S000001943, Chr VI from 245153-244266, reverse complement, Verified ORF, "Quinolinate phosphoribosyl transferase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p" |
| 1809 | YFR048W | RMD8 SGDID:S000001944, Chr VI from 246133-248121, Verified ORF, "Cytosolic protein required for sporulation" |
| 1810 | YFR049W | YMR31 SGDID:S000001945, Chr VI from 248510-248881, Verified ORF, "Mitochondrial ribosomal protein of the small subunit, has similarity to human mitochondrial ribosomal protein MRP-S36" |
| 1811 | YFR050C | PRE4 SGDID:S000001946, Chr VI from 249853-249053, reverse complement, Verified ORF, "Beta 7 subunit of the 20S proteasome" |
| 1812 | YFR051C | RET2 SGDID:S000001947, Chr VI from 251790-250150, reverse complement, Verified ORF, "Delta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER" |
| 1813 | YFR052W | RPN12 SGDID:S000001948, Chr VI from 252492-253316, Verified ORF, "Subunit of the 19S regulatory particle of the 26S proteasome lid; synthetically lethal with RPT1, which is an ATPase component of the 19S regulatory particle; physically interacts with Nob1p and Rpn3p" |
| 1814 | YFR053C | HXK1 SGDID:S000001949, Chr VI from 255036-253579, reverse complement, Verified ORF, "Hexokinase isoenzyme 1, a cytosolic protein that catalyzes phosphorylation of glucose during glucose metabolism; expression is highest during growth on non-glucose carbon sources; glucose-induced repression involves the hexokinase Hxk2p" |
| 1815 | YFR055W | IRC7 SGDID:S000001952, Chr VI from 264191-265213, Uncharacterized ORF, "Putative cystathionine beta-lyase; involved in copper ion homeostasis and sulfur metabolism; null mutant displays increased levels of spontaneous Rad52p foci; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner" |
| 1816 | YFR057W | YFR057W SGDID:S000001953, Chr VI from 269048-269503, Uncharacterized ORF, "Putative protein of unknown function" |
| 1817 | YGL001C | ERG26 SGDID:S000002969, Chr VII from 496506-495457, reverse complement, Verified ORF, "C-3 sterol dehydrogenase, catalyzes the second of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis" |
| 1818 | YGL002W | ERP6 SGDID:S000002970, Chr VII from 494521-495171, Verified ORF, "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 1819 | YGL003C | CDH1 SGDID:S000002971, Chr VII from 494178-492478, reverse complement, Verified ORF, "Cell-cycle regulated activator of the anaphase-promoting complex/cyclosome (APC/C), which directs ubiquitination of cyclins resulting in mitotic exit; targets the APC/C to specific substrates including CDC20, ASE1, CIN8 and FIN1" |
| 1820 | YGL004C | RPN14 SGDID:S000002972, Chr VII from 491960-490707, reverse complement, Uncharacterized ORF, "Putative non-ATPase subunit of the 19S regulatory particle of the 26S proteasome; localized to the cytoplasm" |
| 1821 | YGL005C | COG7 SGDID:S000002973, Chr VII from 490551-489712, reverse complement, Verified ORF, "Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" |
| 1822 | YGL006W | PMC1 SGDID:S000002974, Chr VII from 485925-489446, Verified ORF, "Vacuolar Ca2+ ATPase involved in depleting cytosol of Ca2+ ions; prevents growth inhibition by activation of calcineurin in the presence of elevated concentrations of calcium; similar to mammalian PMCA1a" |
| 1823 | YGL006W-A | YGL006W-A SGDID:S000028769, Chr VII from 485428-485538, Uncharacterized ORF, "Putative protein of unknown function; identified by SAGE" |
| 1824 | YGL007C-A | YGL007C-A SGDID:S000028632, Chr VII from 483032-482946, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; haploid deletion strain exhibits a slow-growth phenotype" |
| 1825 | YGL008C | PMA1 SGDID:S000002976, Chr VII from 482671-479915, reverse complement, Verified ORF, "Plasma membrane H+-ATPase, pumps protons out of the cell; major regulator of cytoplasmic pH and plasma membrane potential; part of the P2 subgroup of cation-transporting ATPases" |
| 1826 | YGL009C | LEU1 SGDID:S000002977, Chr VII from 478657-476318, reverse complement, Verified ORF, "Isopropylmalate isomerase, catalyzes the second step in the leucine biosynthesis pathway" |
| 1827 | YGL010W | YGL010W SGDID:S000002978, Chr VII from 475550-476074, Uncharacterized ORF, "Putative protein of unknown function; YGL010W is not an essential gene" |
| 1828 | YGL011C | SCL1 SGDID:S000002979, Chr VII from 475252-474494, reverse complement, Verified ORF, "Alpha 1 subunit of the 20S core complex of the 26S proteasome involved in the degradation of ubiquitinated substrates; essential for growth; detected in the mitochondria" |
| 1829 | YGL012W | ERG4 SGDID:S000002980, Chr VII from 472860-474281, Verified ORF, "C-24(28) sterol reductase, catalyzes the final step in ergosterol biosynthesis; mutants are viable, but lack ergosterol" |
| 1830 | YGL013C | PDR1 SGDID:S000002981, Chr VII from 472303-469097, reverse complement, Verified ORF, "Zinc cluster protein that is a master regulator involved in recruiting other zinc cluster proteins to pleiotropic drug response elements (PDREs) to fine tune the regulation of multidrug resistance genes" |
| 1831 | YGL014W | PUF4 SGDID:S000002982, Chr VII from 466146-468812, Verified ORF, "Member of the PUF protein family, which is defined by the presence of Pumilio homology domains that confer RNA binding activity; preferentially binds mRNAs encoding nucleolar ribosomal RNA-processing factors" |
| 1832 | YGL015C | YGL015C SGDID:S000002983, Chr VII from 465440-465048, reverse complement, Uncharacterized ORF, "Hypothetical protein" |
| 1833 | YGL016W | KAP122 SGDID:S000002984, Chr VII from 461671-464916, Verified ORF, "Karyopherin beta, responsible for import of the Toa1p-Toa2p complex into the nucleus; binds to nucleoporins Nup1p and Nup2p; may play a role in regulation of pleiotropic drug resistance" |
| 1834 | YGL017W | ATE1 SGDID:S000002985, Chr VII from 459859-461370, Verified ORF, "Arginyl-tRNA-protein transferase, catalyzes post-translational conjugation of arginine to the amino termini of acceptor proteins which are then subject to degradation via the N-end rule pathway" |
| 1835 | YGL018C | JAC1 SGDID:S000002986, Chr VII from 459669-459115, reverse complement, Verified ORF, "Specialized J-protein that functions with Hsp70 in Fe-S cluster biogenesis in mitochondria, involved in iron metabolism; contains a J domain typical to J-type chaperones; localizes to the mitochondrial matrix" |
| 1836 | YGL019W | CKB1 SGDID:S000002987, Chr VII from 458161-458997, Verified ORF, "Beta regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKA2 and CKB2, the many substrates include transcription factors and all RNA polymerases" |
| 1837 | YGL020C | GET1 SGDID:S000002988, Chr VII from 457875-457168, reverse complement, Verified ORF, "Subunit of the GET complex; required for the retrieval of HDEL proteins from the Golgi to the ER in an ERD2 dependent fashion and for normal mitochondrial morphology and inheritance" |
| 1838 | YGL021W | ALK1 SGDID:S000002989, Chr VII from 454790-457072, Verified ORF, "Protein kinase; accumulation and phosphorylation are periodic during the cell cycle; phosphorylated in response to DNA damage; contains characteristic motifs for degradation via the APC pathway; similar to Alk2p and to mammalian haspins" |
| 1839 | YGL022W | STT3 SGDID:S000002990, Chr VII from 452409-454565, Verified ORF, "Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; forms a subcomplex with Ost3p and Ost4p and is directly involved in catalysis" |
| 1840 | YGL023C | PIB2 SGDID:S000002991, Chr VII from 452109-450202, reverse complement, Verified ORF, "Protein binding phosphatidylinositol 3-phosphate, involved in telomere-proximal repression of gene expression; similar to Fab1 and Vps27" |
| 1841 | YGL025C | PGD1 SGDID:S000002993, Chr VII from 449962-448769, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for basal and activated transcription; direct target of Cyc8p-Tup1p transcriptional corepressor" |
| 1842 | YGL026C | TRP5 SGDID:S000002994, Chr VII from 448540-446417, reverse complement, Verified ORF, "Tryptophan synthase involved in tryptophan biosynthesis, regulated by the general control system of amino acid biosynthesis" |
| 1843 | YGL027C | CWH41 SGDID:S000002995, Chr VII from 446148-443647, reverse complement, Verified ORF, "Processing alpha glucosidase I, ER type II integral membrane N-glycoprotein involved in assembly of cell wall beta 1,6 glucan and asparagine-linked protein glycosylation; also involved in ER protein quality control and sensing of ER stress" |
| 1844 | YGL028C | SCW11 SGDID:S000002996, Chr VII from 442914-441286, reverse complement, Verified ORF, "Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on its regulation by Ste12p" |
| 1845 | YGL029W | CGR1 SGDID:S000002997, Chr VII from 440068-440430, Verified ORF, "Protein involved in nucleolar integrity and processing of the pre-rRNA for the 60S ribosome subunit; transcript is induced in response to cytotoxic stress but not genotoxic stress" |
| 1846 | YGL030W | RPL30 SGDID:S000002998, Chr VII from 439096-439098,439329-439643, Verified ORF, "Protein component of the large (60S) ribosomal subunit, has similarity to rat L30 ribosomal protein; involved in pre-rRNA processing in the nucleolus; autoregulates splicing of its transcript" |
| 1847 | YGL031C | RPL24A SGDID:S000002999, Chr VII from 437939-437472, reverse complement, Verified ORF, "Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Bp and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate" |
| 1848 | YGL032C | AGA2 SGDID:S000003000, Chr VII from 436838-436575, reverse complement, Verified ORF, "Adhesion subunit of a-agglutinin of a-cells, C-terminal sequence acts as a ligand for alpha-agglutinin (Sag1p) during agglutination, modified with O-linked oligomannosyl chains, linked to anchorage subunit Aga1p via two disulfide bonds" |
| 1849 | YGL033W | HOP2 SGDID:S000003001, Chr VII from 435630-435684,435755-436356, Verified ORF, "Meiosis-specific protein that localizes to chromosomes, preventing synapsis between nonhomologous chromosomes and ensuring synapsis between homologs; complexes with Mnd1p to promote homolog pairing and meiotic double-strand break repair" |
| 1850 | YGL035C | MIG1 SGDID:S000003003, Chr VII from 433067-431553, reverse complement, Verified ORF, "Transcription factor involved in glucose repression; sequence specific DNA binding protein containing two Cys2His2 zinc finger motifs; regulated by the SNF1 kinase and the GLC7 phosphatase" |
| 1851 | YGL036W | YGL036W SGDID:S000003004, Chr VII from 428606-431335, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YGL036W is not an essential gene" |
| 1852 | YGL037C | PNC1 SGDID:S000003005, Chr VII from 427953-427303, reverse complement, Verified ORF, "Nicotinamidase that converts nicotinamide to nicotinic acid as part of the NAD(+) salvage pathway, required for life span extension by calorie restriction; PNC1 expression responds to all known stimuli that extend replicative life span" |
| 1853 | YGL038C | OCH1 SGDID:S000003006, Chr VII from 426810-425368, reverse complement, Verified ORF, "Mannosyltransferase of the cis-Golgi apparatus, initiates the polymannose outer chain elongation of N-linked oligosaccharides of glycoproteins" |
| 1854 | YGL039W | YGL039W SGDID:S000003007, Chr VII from 423967-425013, Verified ORF, "Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol)" |
| 1855 | YGL040C | HEM2 SGDID:S000003008, Chr VII from 420561-419533, reverse complement, Verified ORF, "Delta-aminolevulinate dehydratase, a homo-octameric enzyme, catalyzes the conversion of delta-aminolevulinic acid to porphobilinogen, the second step in the heme biosynthetic pathway; localizes to both the cytoplasm and nucleus" |
| 1856 | YGL041C-B | YGL041C-B SGDID:S000028548, Chr VII from 418891-418709, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 1857 | YGL041W-A | YGL041W-A SGDID:S000028826, Chr VII from 419047-419295, Uncharacterized ORF, "Putative protein of unknown function, conserved in fungi; identified by expression profiling and mass spectrometry" |
| 1858 | YGL043W | DST1 SGDID:S000003011, Chr VII from 417487-418416, Verified ORF, "General transcription elongation factor TFIIS, enables RNA polymerase II to read through blocks to elongation by stimulating cleavage of nascent transcripts stalled at transcription arrest sites" |
| 1859 | YGL044C | RNA15 SGDID:S000003012, Chr VII from 417040-416150, reverse complement, Verified ORF, "Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of mRNA 3' ends; interacts with the A-rich polyadenylation signal in complex with Rna14p and Hrp1p" |
| 1860 | YGL045W | RIM8 SGDID:S000003013, Chr VII from 414106-415734, Verified ORF, "Protein of unknown function, involved in the proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans PalF" |
| 1861 | YGL047W | ALG13 SGDID:S000003015, Chr VII from 411555-412163, Verified ORF, "Catalytic component of UDP-GlcNAc transferase, required for the second step of dolichyl-linked oligosaccharide synthesis; anchored to the ER membrane via interaction with Alg14p; similar to bacterial and human glycosyltransferases" |
| 1862 | YGL048C | RPT6 SGDID:S000003016, Chr VII from 411289-410072, reverse complement, Verified ORF, "One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; bound by ubiquitin-protein ligases Ubr1p and Ufd4p; localized mainly to the nucleus throughout the cell cycle" |
| 1863 | YGL049C | TIF4632 SGDID:S000003017, Chr VII from 409607-406863, reverse complement, Verified ORF, "Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4631p" |
| 1864 | YGL050W | TYW3 SGDID:S000003018, Chr VII from 405779-406600, Verified ORF, "tRNA methyltransferase required for synthesis of wybutosine, a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions" |
| 1865 | YGL051W | MST27 SGDID:S000003019, Chr VII from 403690-404394, Verified ORF, "Putative integral membrane protein, involved in vesicle formation; forms complex with Mst28p; member of DUP240 gene family; binds COPI and COPII vesicles" |
| 1866 | YGL053W | PRM8 SGDID:S000003021, Chr VII from 402592-403305, Verified ORF, "Pheromone-regulated protein with 2 predicted transmembrane segments and an FF sequence, a motif involved in COPII binding; forms a complex with Prp9p in the ER; member of DUP240 gene family" |
| 1867 | YGL054C | ERV14 SGDID:S000003022, Chr VII from 401290-400874, reverse complement, Verified ORF, "Protein localized to COPII-coated vesicles, involved in vesicle formation and incorporation of specific secretory cargo; required for the delivery of bud-site selection protein Axl2p to cell surface; related to Drosophila cornichon" |
| 1868 | YGL055W | OLE1 SGDID:S000003023, Chr VII from 398631-400163, Verified ORF, "Delta(9) fatty acid desaturase, required for monounsaturated fatty acid synthesis and for normal distribution of mitochondria" |
| 1869 | YGL056C | SDS23 SGDID:S000003024, Chr VII from 397624-396041, reverse complement, Verified ORF, "One of two S. cerevisiae homologs (Sds23p and Sds24p) of the Schizosaccharomyces pombe Sds23 protein, which genetic studies have implicated in APC/cyclosome regulation" |
| 1870 | YGL057C | YGL057C SGDID:S000003025, Chr VII from 395835-394972, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant exhibits a growth defect on a non-fermentable (respiratory) carbon source" |
| 1871 | YGL058W | RAD6 SGDID:S000003026, Chr VII from 393992-394510, Verified ORF, "Ubiquitin-conjugating enzyme (E2), involved in postreplication repair (with Rad18p), sporulation, telomere silencing, and ubiquitin-mediated N-end rule protein degradation (with Ubr1p)" |
| 1872 | YGL059W | PKP2 SGDID:S000003027, Chr VII from 392228-393703, Verified ORF, "Mitochondrial protein kinase that negatively regulates activity of the pyruvate dehydrogenase complex by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp1p and phosphatases Ptc5p and Ptc6p" |
| 1873 | YGL060W | YBP2 SGDID:S000003028, Chr VII from 390070-391995, Verified ORF, "Central kinetochore associated protein that mediates mitotic progression; interacts with several central kinetochore proteins and the centromeric histone Cse4p; role in resistance to oxidative stress; similarity to Ybp1p and Slk19p" |
| 1874 | YGL061C | DUO1 SGDID:S000003029, Chr VII from 389714-388971, reverse complement, Verified ORF, "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" |
| 1875 | YGL062W | PYC1 SGDID:S000003030, Chr VII from 385199-388735, Verified ORF, "Pyruvate carboxylase isoform, cytoplasmic enzyme that converts pyruvate to oxaloacetate; highly similar to isoform Pyc2p but differentially regulated; mutations in the human homolog are associated with lactic acidosis" |
| 1876 | YGL063W | PUS2 SGDID:S000003031, Chr VII from 383657-384769, Verified ORF, "Mitochondrial tRNA:pseudouridine synthase; acts at positions 27 and 28, but not at position 72; efficiently and rapidly targeted to mitochondria, specifically dedicated to mitochondrial tRNA modification" |
| 1877 | YGL064C | MRH4 SGDID:S000003032, Chr VII from 383211-381526, reverse complement, Verified ORF, "Mitochondrial ATP-dependent RNA helicase of the DEAD-box family, plays an essential role in mitochondrial function" |
| 1878 | YGL065C | ALG2 SGDID:S000003033, Chr VII from 381274-379763, reverse complement, Verified ORF, "Mannosyltransferase that catalyzes two consecutive steps in the N-linked glycosylation pathway; alg2 mutants exhibit temperature-sensitive growth and abnormal accumulation of the lipid-linked oligosaccharide Man2GlcNAc2-PP-Dol" |
| 1879 | YGL066W | SGF73 SGDID:S000003034, Chr VII from 377612-379585, Verified ORF, "Subunit of SAGA histone acetyltransferase complex; involved in formation of the preinitiation complex assembly at promoters; null mutant displays defects in premeiotic DNA synthesis" |
| 1880 | YGL067W | NPY1 SGDID:S000003035, Chr VII from 376104-377258, Verified ORF, "NADH diphosphatase (pyrophosphatase), hydrolyzes the pyrophosphate linkage in NADH and related nucleotides; localizes to peroxisomes" |
| 1881 | YGL068W | MNP1 SGDID:S000003036, Chr VII from 375090-375674, Verified ORF, "Protein associated with the mitochondrial nucleoid; putative mitochondrial ribosomal protein with similarity to E. coli L7/L12 ribosomal protein; required for normal respiratory growth" |
| 1882 | YGL070C | RPB9 SGDID:S000003038, Chr VII from 374830-374462, reverse complement, Verified ORF, "RNA polymerase II subunit B12.6; contacts DNA; mutations affect transcription start site; involved in telomere maintenance" |
| 1883 | YGL071W | AFT1 SGDID:S000003039, Chr VII from 372015-374087, Verified ORF, "Transcription factor involved in iron utilization and homeostasis; binds the consensus site PyPuCACCCPu and activates the expression of target genes in response to changes in iron availability" |
| 1884 | YGL073W | HSF1 SGDID:S000003041, Chr VII from 368756-371257, Verified ORF, "Trimeric heat shock transcription factor, activates multiple genes in response to stresses that include hyperthermia; recognizes variable heat shock elements (HSEs) consisting of inverted NGAAN repeats; posttranslationally regulated" |
| 1885 | YGL075C | MPS2 SGDID:S000003043, Chr VII from 368091-366928, reverse complement, Verified ORF, "Essential membrane protein localized at the nuclear envelope and spindle pole body (SPB), required for insertion of the newly duplicated SPB into the nuclear envelope; potentially phosphorylated by Cdc28p" |
| 1886 | YGL076C | RPL7A SGDID:S000003044, Chr VII from 365999-365989,365529-365436,364967-364338, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Bp and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2)" |
| 1887 | YGL077C | HNM1 SGDID:S000003045, Chr VII from 363919-362228, reverse complement, Verified ORF, "Choline/ethanolamine transporter; involved in the uptake of nitrogen mustard and the uptake of glycine betaine during hypersaline stress; co-regulated with phospholipid biosynthetic genes and negatively regulated by choline and myo-inositol" |
| 1888 | YGL078C | DBP3 SGDID:S000003046, Chr VII from 361862-360291, reverse complement, Verified ORF, "Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis" |
| 1889 | YGL079W | YGL079W SGDID:S000003047, Chr VII from 359447-360103, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endosome; identified as a transcriptional activator in a high-throughput yeast one-hybrid assay" |
| 1890 | YGL080W | YGL080W SGDID:S000003048, Chr VII from 358639-359031, Uncharacterized ORF, "Putative protein of unknown function; highly conserved across species and orthologous to human gene BRP44L; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 1891 | YGL081W | YGL081W SGDID:S000003049, Chr VII from 357380-358342, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene; interacts genetically with CHS5, a gene involved in chitin biosynthesis" |
| 1892 | YGL082W | YGL082W SGDID:S000003050, Chr VII from 355830-356975, Uncharacterized ORF, "Putative protein of unknown function; predicted prenylation/proteolysis target of Afc1p and Rce1p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YGL082W is not an essential gene" |
| 1893 | YGL083W | SCY1 SGDID:S000003051, Chr VII from 353061-355475, Verified ORF, "Putative kinase, suppressor of GTPase mutant, similar to bovine rhodopsin kinase" |
| 1894 | YGL084C | GUP1 SGDID:S000003052, Chr VII from 352301-350619, reverse complement, Verified ORF, "Plasma membrane protein involved in remodeling GPI anchors; member of the MBOAT family of putative membrane-bound O-acyltransferases; proposed to be involved in glycerol transport" |
| 1895 | YGL085W | YGL085W SGDID:S000003053, Chr VII from 349619-350443, Uncharacterized ORF, "Putative protein of unknown function, has homology to Staphylococcus aureus nuclease; green fluorescent protein (GFP)-fusion protein localizes to mitochondria and is induced in response to the DNA-damaging agent MMS" |
| 1896 | YGL086W | MAD1 SGDID:S000003054, Chr VII from 347122-349371, Verified ORF, "Coiled-coil protein involved in the spindle-assembly checkpoint; phosphorylated by Mps1p upon checkpoint activation which leads to inhibition of the activity of the anaphase promoting complex; forms a complex with Mad2p" |
| 1897 | YGL087C | MMS2 SGDID:S000003055, Chr VII from 346907-346897,346811-346409, reverse complement, Verified ORF, "Protein involved in error-free postreplication DNA repair; forms a heteromeric complex with Ubc13p that has a ubiquitin-conjugating activity; cooperates with chromatin-associated RING finger proteins, Rad18p and Rad5p" |
| 1898 | YGL089C | MF(ALPHA)2 SGDID:S000003057, Chr VII from 345156-344794, reverse complement, Verified ORF, "Mating pheromone alpha-factor, made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)1, which is more highly expressed than MF(ALPHA)2" |
| 1899 | YGL090W | LIF1 SGDID:S000003058, Chr VII from 343322-344587, Verified ORF, "Component of the DNA ligase IV complex that mediates nonhomologous end joining in DNA double-strand break repair; physically interacts with Dnl4p and Nej1p; homologous to mammalian XRCC4 protein" |
| 1900 | YGL091C | NBP35 SGDID:S000003059, Chr VII from 343045-342059, reverse complement, Verified ORF, "Essential iron-sulfur cluster binding protein localized in the cytoplasm; forms a complex with Cfd1p that is involved in iron-sulfur protein assembly in the cytosol; similar to P-loop NTPases" |
| 1901 | YGL092W | NUP145 SGDID:S000003060, Chr VII from 337909-341862, Verified ORF, "Essential nucleoporin, catalyzes its own cleavage in vivo to generate a C-terminal fragment that assembles into the Nup84p subcomplex of the nuclear pore complex, and an N-terminal fragment of unknown function that is homologous to Nup100p" |
| 1902 | YGL093W | SPC105 SGDID:S000003061, Chr VII from 334889-337642, Verified ORF, "Protein required for accurate chromosome segregation, localizes to the nuclear side of the spindle pole body; forms a complex with Ydr532cp" |
| 1903 | YGL094C | PAN2 SGDID:S000003062, Chr VII from 334468-331121, reverse complement, Verified ORF, "Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes" |
| 1904 | YGL095C | VPS45 SGDID:S000003063, Chr VII from 330610-328877, reverse complement, Verified ORF, "Protein of the Sec1p/Munc-18 family, essential for vacuolar protein sorting; required for the function of Pep12p and the early endosome/late Golgi SNARE Tlg2p; essential for fusion of Golgi-derived vesicles with the prevacuolar compartment" |
| 1905 | YGL096W | TOS8 SGDID:S000003064, Chr VII from 325334-326164, Verified ORF, "Homeodomain-containing transcription factor; SBF regulated target gene that in turn regulates expression of genes involved in G1/S phase events such as bud site selection, bud emergence and cell cycle progression; similarity to Cup9p" |
| 1906 | YGL097W | SRM1 SGDID:S000003065, Chr VII from 321785-323233, Verified ORF, "Nucleotide exchange factor for Gsp1p, localizes to the nucleus, required for nucleocytoplasmic trafficking of macromolecules; suppressor of the pheromone response pathway; potentially phosphorylated by Cdc28p" |
| 1907 | YGL098W | USE1 SGDID:S000003066, Chr VII from 317345-318082, Verified ORF, "Essential SNARE protein localized to the ER, involved in retrograde traffic from the Golgi to the ER; forms a complex with the SNAREs Sec22p, Sec20p and Ufe1p" |
| 1908 | YGL099W | LSG1 SGDID:S000003067, Chr VII from 314634-316556, Verified ORF, "Putative GTPase involved in 60S ribosomal subunit biogenesis; required for the release of Nmd3p from 60S subunits in the cytoplasm" |
| 1909 | YGL100W | SEH1 SGDID:S000003068, Chr VII from 313237-314286, Verified ORF, "Nuclear pore protein that is part of the evolutionarily conserved Nup84p complex (Nup84p, Nup85p, Nup120p, Nup145p, and Seh1p); homologous to Sec13p" |
| 1910 | YGL101W | YGL101W SGDID:S000003069, Chr VII from 312196-312843, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene with similarity to YBR242W; interacts with the DNA helicase Hpr5p" |
| 1911 | YGL103W | RPL28 SGDID:S000003071, Chr VII from 310970-311018,311530-311930, Verified ORF, "Ribosomal protein of the large (60S) ribosomal subunit, has similarity to E. coli L15 and rat L27a ribosomal proteins; may have peptidyl transferase activity; can mutate to cycloheximide resistance" |
| 1912 | YGL104C | VPS73 SGDID:S000003072, Chr VII from 310176-308716, reverse complement, Verified ORF, "Mitochondrial protein; mutation affects vacuolar protein sorting; putative transporter; member of the sugar porter family" |
| 1913 | YGL105W | ARC1 SGDID:S000003073, Chr VII from 307440-308570, Verified ORF, "Protein that binds tRNA and methionyl- and glutamyl-tRNA synthetases (Mes1p and Gus1p), delivering tRNA to them, stimulating catalysis, and ensuring their localization to the cytoplasm; also binds quadruplex nucleic acids" |
| 1914 | YGL106W | MLC1 SGDID:S000003074, Chr VII from 306563-307012, Verified ORF, "Essential light chain for Myo1p, light chain for Myo2p; stabilizes Myo2p by binding to the neck region; interacts with Myo1p, Iqg1p, and Myo2p to coordinate formation and contraction of the actomyosin ring with targeted membrane deposition" |
| 1915 | YGL107C | RMD9 SGDID:S000003075, Chr VII from 306276-304336, reverse complement, Verified ORF, "Mitochondrial protein required for respiratory growth; mutant phenotype and genetic interactions suggest a role in delivering mt mRNAs to ribosomes; located on matrix face of the inner membrane and loosely associated with mitoribosomes" |
| 1916 | YGL108C | YGL108C SGDID:S000003076, Chr VII from 304074-303652, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery" |
| 1917 | YGL110C | CUE3 SGDID:S000003078, Chr VII from 303414-301540, reverse complement, Verified ORF, "Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination" |
| 1918 | YGL111W | NSA1 SGDID:S000003079, Chr VII from 299981-301372, Verified ORF, "Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis" |
| 1919 | YGL112C | TAF6 SGDID:S000003080, Chr VII from 299731-298181, reverse complement, Verified ORF, "Subunit (60 kDa) of TFIID and SAGA complexes, involved in transcription initiation of RNA polymerase II and in chromatin modification, similar to histone H4" |
| 1920 | YGL113W | SLD3 SGDID:S000003081, Chr VII from 295935-297941, Verified ORF, "Protein involved in the initiation of DNA replication, required for proper assembly of replication proteins at the origins of replication; interacts with Cdc45p" |
| 1921 | YGL114W | YGL114W SGDID:S000003082, Chr VII from 293463-295640, Uncharacterized ORF, "Putative protein of unknown function; predicted member of the oligopeptide transporter (OPT) family of membrane transporters" |
| 1922 | YGL115W | SNF4 SGDID:S000003083, Chr VII from 292036-293004, Verified ORF, "Activating gamma subunit of the AMP-activated Snf1p kinase complex (contains Snf1p and a Sip1p/Sip2p/Gal83p family member); activates glucose-repressed genes, represses glucose-induced genes; role in sporulation, and peroxisome biogenesis" |
| 1923 | YGL116W | CDC20 SGDID:S000003084, Chr VII from 289812-291644, Verified ORF, "Cell-cycle regulated activator of anaphase-promoting complex/cyclosome (APC/C), which is required for metaphase/anaphase transition; directs ubiquitination of mitotic cyclins, Pds1p, and other anaphase inhibitors; potential Cdc28p substrate" |
| 1924 | YGL117W | YGL117W SGDID:S000003085, Chr VII from 288518-289315, Uncharacterized ORF, "Putative protein of unknown function" |
| 1925 | YGL119W | ABC1 SGDID:S000003087, Chr VII from 284448-285953, Verified ORF, "Protein required for ubiquinone (coenzyme Q) biosynthesis and for respiratory growth; exhibits genetic interaction with COQ9, suggesting a common function; similar to prokaryotic proteins involved in early steps of ubiquinone biosynthesis" |
| 1926 | YGL120C | PRP43 SGDID:S000003088, Chr VII from 283943-281640, reverse complement, Verified ORF, "RNA helicase in the DEAH-box family, functions in both RNA polymerase I and polymerase II transcript metabolism, involved in release of the lariat-intron from the spliceosome" |
| 1927 | YGL121C | GPG1 SGDID:S000003089, Chr VII from 281163-280783, reverse complement, Verified ORF, "Proposed gamma subunit of the heterotrimeric G protein that interacts with the receptor Grp1p; involved in regulation of pseudohyphal growth; requires Gpb1p or Gpb2p to interact with Gpa2p" |
| 1928 | YGL122C | NAB2 SGDID:S000003090, Chr VII from 280529-278952, reverse complement, Verified ORF, "Nuclear polyadenylated RNA-binding protein; autoregulates mRNA levels; related to human hnRNPs; has nuclear localization signal sequence that binds to Kap104p; required for poly(A) tail length control and nuclear mRNA export" |
| 1929 | YGL123W | RPS2 SGDID:S000003091, Chr VII from 277623-278387, Verified ORF, "Protein component of the small (40S) subunit, essential for control of translational accuracy; has similarity to E. coli S5 and rat S2 ribosomal proteins" |
| 1930 | YGL124C | MON1 SGDID:S000003092, Chr VII from 276720-274786, reverse complement, Verified ORF, "Protein required for fusion of cvt-vesicles and autophagosomes with the vacuole; associates, as a complex with Ccz1p, with a perivacuolar compartment; potential Cdc28p substrate" |
| 1931 | YGL125W | MET13 SGDID:S000003093, Chr VII from 272526-274328, Verified ORF, "Isozyme of methylenetetrahydrofolate reductase, catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway" |
| 1932 | YGL126W | SCS3 SGDID:S000003094, Chr VII from 271003-272145, Verified ORF, "Protein required for inositol prototrophy, identified as an ortholog of the FIT family of proteins involved in triglyceride droplet biosynthesis; disputed role in the synthesis of inositol phospholipids from inositol" |
| 1933 | YGL127C | SOH1 SGDID:S000003095, Chr VII from 270781-270398, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; involved in telomere maintenance; conserved with other metazoan MED31 subunits" |
| 1934 | YGL128C | CWC23 SGDID:S000003096, Chr VII from 270150-269299, reverse complement, Verified ORF, "Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to E. coli DnaJ and other DnaJ-like proteins and to S. pombe Cwf23p" |
| 1935 | YGL129C | RSM23 SGDID:S000003097, Chr VII from 269194-267728, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the small subunit, has similarity to mammalian apoptosis mediator proteins; null mutation prevents induction of apoptosis by overproduction of metacaspase Mca1p" |
| 1936 | YGL130W | CEG1 SGDID:S000003098, Chr VII from 266150-267529, Verified ORF, "Alpha (guanylyltransferase) subunit of the mRNA capping enzyme, a heterodimer (the other subunit is CET1, an RNA 5'-triphophatase) involved in adding the 5' cap to mRNA; the mammalian enzyme is a single bifunctional polypeptide" |
| 1937 | YGL131C | SNT2 SGDID:S000003099, Chr VII from 265864-261653, reverse complement, Verified ORF, "DNA binding protein with similarity to the S. pombe Snt2 protein" |
| 1938 | YGL133W | ITC1 SGDID:S000003101, Chr VII from 257712-261506, Verified ORF, "Component of the ATP-dependent Isw2p-Itc1p chromatin remodeling complex, required for repression of a-specific genes, repression of early meiotic genes during mitotic growth, and repression of INO1" |
| 1939 | YGL134W | PCL10 SGDID:S000003102, Chr VII from 255668-256969, Verified ORF, "Pho85p cyclin; recruits, activates, and targets Pho85p cyclin-dependent protein kinase to its substrate" |
| 1940 | YGL135W | RPL1B SGDID:S000003103, Chr VII from 254646-255299, Verified ORF, "N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1Ap and has similarity to E. coli L1 and rat L10a ribosomal proteins; rpl1a rpl1b double null mutation is lethal" |
| 1941 | YGL136C | MRM2 SGDID:S000003104, Chr VII from 253864-252902, reverse complement, Verified ORF, "Mitochondrial 2' O-ribose methyltransferase, required for methylation of U(2791) in 21S rRNA; MRM2 deletion confers thermosensitive respiration and loss of mitochondrial DNA; has similarity to Spb1p and Trm7p, and to E. coli FtsJ/RrmJ" |
| 1942 | YGL137W | SEC27 SGDID:S000003105, Chr VII from 249874-249891,250092-252743, Verified ORF, "Essential beta'-coat protein of the COPI coatomer, involved in ER-to-Golgi and Golgi-to-ER transport; contains WD40 domains that mediate cargo selective interactions; 45% sequence identity to mammalian beta'-COP" |
| 1943 | YGL138C | YGL138C SGDID:S000003106, Chr VII from 249536-248499, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; has no significant sequence similarity to any known protein" |
| 1944 | YGL139W | FLC3 SGDID:S000003107, Chr VII from 245721-248129, Verified ORF, "Putative FAD transporter, similar to Flc1p and Flc2p; localized to the ER" |
| 1945 | YGL140C | YGL140C SGDID:S000003108, Chr VII from 245017-241358, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene; contains multiple predicted transmembrane domains" |
| 1946 | YGL141W | HUL5 SGDID:S000003109, Chr VII from 238358-241090, Verified ORF, "Ubiquitin-conjugating enzyme (E4), elongates polyubiquitin chains on substrate proteins; works in opposition to Ubp6p polyubiquitin-shortening activity; required for retrograde transport of misfolded proteins into cytoplasm during ERAD" |
| 1947 | YGL142C | GPI10 SGDID:S000003110, Chr VII from 238124-236274, reverse complement, Verified ORF, "Integral membrane protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis; putative alpha 1,2 mannosyltransferase required for addition of the third mannose onto the GPI core structure; human PIG-Bp is a functional homolog" |
| 1948 | YGL143C | MRF1 SGDID:S000003111, Chr VII from 235963-234722, reverse complement, Verified ORF, "Mitochondrial translation release factor, involved in stop codon recognition and hydrolysis of the peptidyl-tRNA bond during mitochondrial translation; lack of MRF1 causes mitochondrial genome instability" |
| 1949 | YGL144C | ROG1 SGDID:S000003112, Chr VII from 234512-232455, reverse complement, Verified ORF, "Protein with putative serine active lipase domain" |
| 1950 | YGL145W | TIP20 SGDID:S000003113, Chr VII from 230248-232353, Verified ORF, "Peripheral membrane protein required for fusion of COPI vesicles with the ER, prohibits back-fusion of COPII vesicles with the ER, may act as a sensor for vesicles at the ER membrane; interacts with Sec20p" |
| 1951 | YGL146C | YGL146C SGDID:S000003114, Chr VII from 229691-228756, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, contains two putative transmembrane spans, shows no significant homology to any other known protein sequence, YGL146C is not an essential gene" |
| 1952 | YGL147C | RPL9A SGDID:S000003115, Chr VII from 228334-227759, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Bp and has similarity to E. coli L6 and rat L9 ribosomal proteins" |
| 1953 | YGL148W | ARO2 SGDID:S000003116, Chr VII from 226404-227534, Verified ORF, "Bifunctional chorismate synthase and flavin reductase, catalyzes the conversion of 5-enolpyruvylshikimate 3-phosphate (EPSP) to form chorismate, which is a precursor to aromatic amino acids" |
| 1954 | YGL150C | INO80 SGDID:S000003118, Chr VII from 225578-221109, reverse complement, Verified ORF, "ATPase that forms a large complex, containing actin and several actin-related proteins, that has chromatin remodeling activity and 3' to 5' DNA helicase activity in vitro; shows similarity to the Snf2p family of ATPases" |
| 1955 | YGL151W | NUT1 SGDID:S000003119, Chr VII from 217529-220927, Verified ORF, "Component of the RNA polymerase II mediator complex, which is required for transcriptional activation and also has a role in basal transcription" |
| 1956 | YGL153W | PEX14 SGDID:S000003121, Chr VII from 216278-217303, Verified ORF, "Peroxisomal membrane peroxin that is a central component of the peroxisomal protein import machinery; interacts with both PTS1 (Pex5p) and PTS2 (Pex7p), peroxisomal matrix protein signal recognition factors and membrane receptor Pex13p" |
| 1957 | YGL154C | LYS5 SGDID:S000003122, Chr VII from 216101-215283, reverse complement, Verified ORF, "Phosphopantetheinyl transferase involved in lysine biosynthesis; converts inactive apo-form of Lys2p (alpha-aminoadipate reductase) into catalytically active holo-form by posttranslational addition of phosphopantetheine" |
| 1958 | YGL155W | CDC43 SGDID:S000003123, Chr VII from 214086-215216, Verified ORF, "Beta subunit of geranylgeranyltransferase type I, catalyzes geranylgeranylation to the cysteine residue in proteins containing a C-terminal CaaX sequence ending in Leu or Phe; has substrates important for morphogenesis" |
| 1959 | YGL156W | AMS1 SGDID:S000003124, Chr VII from 210421-213672, Verified ORF, "Vacuolar alpha mannosidase, involved in free oligosaccharide (fOS) degradation; delivered to the vacuole in a novel pathway separate from the secretory pathway" |
| 1960 | YGL157W | YGL157W SGDID:S000003125, Chr VII from 209011-210054, Verified ORF, "Oxidoreductase, catalyzes NADPH-dependent reduction of the bicyclic diketone bicyclo[2.2.2]octane-2,6-dione (BCO2,6D) to the chiral ketoalcohol (1R,4S,6S)-6-hydroxybicyclo[2.2.2]octane-2-one (BCO2one6ol)" |
| 1961 | YGL158W | RCK1 SGDID:S000003126, Chr VII from 207038-208576, Verified ORF, "Protein kinase involved in the response to oxidative stress; identified as suppressor of S. pombe cell cycle checkpoint mutations" |
| 1962 | YGL159W | YGL159W SGDID:S000003127, Chr VII from 202727-203839, Uncharacterized ORF, "Putative protein of unknown function; deletion mutant has no detectable phenotype" |
| 1963 | YGL160W | YGL160W SGDID:S000003128, Chr VII from 200567-202279, Verified ORF, "Putative protein of unknown function; similar to iron/copper reductases (FRE1-8), possibly involved in iron homeostasis; may interact with ribosomes, null mutant displays increased frequency of mitochondrial genome loss (petite formation)" |
| 1964 | YGL161C | YIP5 SGDID:S000003129, Chr VII from 200148-199216, reverse complement, Verified ORF, "Protein that interacts with Rab GTPases, localized to late Golgi vesicles; computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport" |
| 1965 | YGL162W | SUT1 SGDID:S000003130, Chr VII from 198144-199043, Verified ORF, "Transcription factor of the Zn[II]2Cys6 family involved in sterol uptake; involved in induction of hypoxic gene expression" |
| 1966 | YGL163C | RAD54 SGDID:S000003131, Chr VII from 196409-193713, reverse complement, Verified ORF, "DNA-dependent ATPase, stimulates strand exchange by modifying the topology of double-stranded DNA; involved in the recombinational repair of double-strand breaks in DNA during vegetative growth and meiosis; member of the SWI/SNF family" |
| 1967 | YGL164C | YRB30 SGDID:S000003132, Chr VII from 193306-191984, reverse complement, Verified ORF, "RanGTP-binding protein, inhibits RanGAP1 (Rna1p)-mediated GTP hydrolysis of RanGTP (Gsp1p); shares similarity to proteins in other fungi but not in higher eukaryotes" |
| 1968 | YGL166W | CUP2 SGDID:S000003134, Chr VII from 191135-191812, Verified ORF, "Copper-binding transcription factor; activates transcription of the metallothionein genes CUP1-1 and CUP1-2 in response to elevated copper concentrations" |
| 1969 | YGL167C | PMR1 SGDID:S000003135, Chr VII from 190474-187622, reverse complement, Verified ORF, "High affinity Ca2+/Mn2+ P-type ATPase required for Ca2+ and Mn2+ transport into Golgi; involved in Ca2+ dependent protein sorting and processing; mutations in human homolog ATP2C1 cause acantholytic skin condition Hailey-Hailey disease" |
| 1970 | YGL168W | HUR1 SGDID:S000003136, Chr VII from 187470-187802, Verified ORF, "Protein of unknown function; reported null mutant phenotype of hydroxyurea sensitivity may be due to effects on overlapping PMR1 gene" |
| 1971 | YGL169W | SUA5 SGDID:S000003137, Chr VII from 186065-187345, Verified ORF, "Protein required for respiratory growth; null mutation suppresses the Cyc1p translation defect caused by the presence of an aberrant ATG codon upstream of the correct start" |
| 1972 | YGL170C | SPO74 SGDID:S000003138, Chr VII from 185400-184159, reverse complement, Verified ORF, "Component of the meiotic outer plaque of the spindle pole body, involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation" |
| 1973 | YGL171W | ROK1 SGDID:S000003139, Chr VII from 182396-184090, Verified ORF, "ATP-dependent RNA helicase of the DEAD box family; required for 18S rRNA synthesis" |
| 1974 | YGL172W | NUP49 SGDID:S000003140, Chr VII from 180706-182124, Verified ORF, "Subunit of the Nsp1p-Nup57p-Nup49p-Nic96p subcomplex of the nuclear pore complex (NPC), required for nuclear export of ribosomes" |
| 1975 | YGL173C | KEM1 SGDID:S000003141, Chr VII from 180119-175533, reverse complement, Verified ORF, "Evolutionarily-conserved 5'-3' exonuclease component of cytoplasmic processing (P) bodies involved in mRNA decay; plays a role in microtubule-mediated processes, filamentous growth, ribosomal RNA maturation, and telomere maintenance" |
| 1976 | YGL174W | BUD13 SGDID:S000003142, Chr VII from 174551-175351, Verified ORF, "Subunit of the RES complex, which is required for nuclear pre-mRNA retention and splicing; involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern" |
| 1977 | YGL175C | SAE2 SGDID:S000003143, Chr VII from 174328-173291, reverse complement, Verified ORF, "Endonuclease that processes hairpin DNA structures with the MRX complex; involved in meiotic and mitotic double-strand break repair; phosphorylated in response to DNA damage and required for normal resistance to DNA-damaging agents" |
| 1978 | YGL176C | YGL176C SGDID:S000003144, Chr VII from 173085-171421, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; deletion mutant is viable and has no detectable phenotype" |
| 1979 | YGL178W | MPT5 SGDID:S000003146, Chr VII from 167358-167360,168001-170577, Verified ORF, "Member of the Puf family of RNA-binding proteins; binds to mRNAs encoding chromatin modifiers and spindle pole body components; involved in longevity, maintenance of cell wall integrity, and sensitivity to and recovery from pheromone arrest" |
| 1980 | YGL179C | TOS3 SGDID:S000003147, Chr VII from 165097-163415, reverse complement, Verified ORF, "Protein kinase, related to and functionally redundant with Elm1p and Sak1p for the phosphorylation and activation of Snf1p; functionally orthologous to LKB1, a mammalian kinase associated with Peutz-Jeghers cancer-susceptibility syndrome" |
| 1981 | YGL180W | ATG1 SGDID:S000003148, Chr VII from 160071-162764, Verified ORF, "Protein serine/threonine kinase required for vesicle formation in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; structurally required for pre-autophagosome formation; during autophagy forms a complex with Atg13p and Atg17p" |
| 1982 | YGL181W | GTS1 SGDID:S000003149, Chr VII from 157912-159102, Verified ORF, "Protein that localizes to the nucleus and is involved in transcription regulation; also localizes to actin patches and plays a role in endocytosis; N-terminus contains an ARF-GAP domain and C-terminus contains a Gln-rich domain" |
| 1983 | YGL183C | MND1 SGDID:S000003151, Chr VII from 157291-157289,157205-156549, reverse complement, Verified ORF, "Protein required for recombination and meiotic nuclear division; forms a complex with Hop2p, which is involved in chromosome pairing and repair of meiotic double-strand breaks" |
| 1984 | YGL184C | STR3 SGDID:S000003152, Chr VII from 156018-154621, reverse complement, Verified ORF, "Cystathionine beta-lyase, converts cystathionine into homocysteine" |
| 1985 | YGL185C | YGL185C SGDID:S000003153, Chr VII from 154312-153173, reverse complement, Uncharacterized ORF, "Putative protein with sequence similarity to hydroxyacid dehydrogenases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 1986 | YGL186C | TPN1 SGDID:S000003154, Chr VII from 152782-151043, reverse complement, Verified ORF, "Plasma membrane pyridoxine (vitamin B6) transporter; member of the purine-cytosine permease subfamily within the major facilitator superfamily; proton symporter with similarity to Fcy21p, Fcy2p, and Fcy22p" |
| 1987 | YGL187C | COX4 SGDID:S000003155, Chr VII from 150177-149710, reverse complement, Verified ORF, "Subunit IV of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; N-terminal 25 residues of precursor are cleaved during mitochondrial import; phosphorylated" |
| 1988 | YGL188C-A | YGL188C-A SGDID:S000028635, Chr VII from 148970-148830, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 1989 | YGL189C | RPS26A SGDID:S000003157, Chr VII from 148594-148235, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps26Bp and has similarity to rat S26 ribosomal protein" |
| 1990 | YGL190C | CDC55 SGDID:S000003158, Chr VII from 147395-145815, reverse complement, Verified ORF, "Non-essential regulatory subunit B of protein phosphatase 2A, which has multiple roles in mitosis and protein biosynthesis; involved in regulation of mitotic exit; found in the nucleus of most cells, also at the bud neck and at the bud tip" |
| 1991 | YGL191W | COX13 SGDID:S000003159, Chr VII from 144814-145203, Verified ORF, "Subunit VIa of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; not essential for cytochrome c oxidase activity but may modulate activity in response to ATP" |
| 1992 | YGL192W | IME4 SGDID:S000003160, Chr VII from 142252-144054, Verified ORF, "Probable mRNA N6-adenosine methyltransferase that is required for IME1 transcript accumulation and for sporulation; expression is induced in starved MATa/MAT alpha diploid cells" |
| 1993 | YGL193C | YGL193C SGDID:S000003161, Chr VII from 142233-141922, reverse complement, Uncharacterized ORF, "Haploid-specific gene repressed by a1-alpha2, turned off in sir3 null strains, absence enhances the sensitivity of rad52-327 cells to campothecin almost 100-fold" |
| 1994 | YGL194C | HOS2 SGDID:S000003162, Chr VII from 141732-140374, reverse complement, Verified ORF, "Histone deacetylase required for gene activation via specific deacetylation of lysines in H3 and H4 histone tails; subunit of the Set3 complex, a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity" |
| 1995 | YGL194C-A | YGL194C-A SGDID:S000087160, Chr VII from 139967-139725, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, identified based on comparisons of the genome sequences of six Saccharomyces species" |
| 1996 | YGL195W | GCN1 SGDID:S000003163, Chr VII from 131531-139549, Verified ORF, "Positive regulator of the Gcn2p kinase activity, forms a complex with Gcn20p; proposed to stimulate Gcn2p activation by an uncharged tRNA" |
| 1997 | YGL196W | DSD1 SGDID:S000003164, Chr VII from 129888-131174, Verified ORF, "D-serine dehydratase (aka D-serine ammonia-lyase); converts D-serine to pyruvate and ammonia; specifc for D-serine, unlike the bacterial enzyme which recognizes both D-serine and L-serine as substrates" |
| 1998 | YGL197W | MDS3 SGDID:S000003165, Chr VII from 124703-129166, Verified ORF, "Protein with an N-terminal kelch-like domain, putative negative regulator of early meiotic gene expression; required, with Pmd1p, for growth under alkaline conditions" |
| 1999 | YGL198W | YIP4 SGDID:S000003166, Chr VII from 123596-124303, Verified ORF, "Protein that interacts with Rab GTPases, localized to late Golgi vesicles; computational analysis of large-scale protein-protein interaction data suggests a possible role in vesicle-mediated transport" |
| 2000 | YGL200C | EMP24 SGDID:S000003168, Chr VII from 123310-122699, reverse complement, Verified ORF, "Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport" |
| 2001 | YGL201C | MCM6 SGDID:S000003169, Chr VII from 120911-117858, reverse complement, Verified ORF, "Protein involved in DNA replication; component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex" |
| 2002 | YGL202W | ARO8 SGDID:S000003170, Chr VII from 116063-117565, Verified ORF, "Aromatic aminotransferase I, expression is regulated by general control of amino acid biosynthesis" |
| 2003 | YGL203C | KEX1 SGDID:S000003171, Chr VII from 114668-112479, reverse complement, Verified ORF, "Protease involved in the processing of killer toxin and alpha factor precursor; cleaves Lys and Arg residues from the C-terminus of peptides and proteins" |
| 2004 | YGL205W | POX1 SGDID:S000003173, Chr VII from 108162-110408, Verified ORF, "Fatty-acyl coenzyme A oxidase, involved in the fatty acid beta-oxidation pathway; localized to the peroxisomal matrix" |
| 2005 | YGL206C | CHC1 SGDID:S000003174, Chr VII from 107508-102547, reverse complement, Verified ORF, "Clathrin heavy chain, subunit of the major coat protein involved in intracellular protein transport and endocytosis; two heavy chains form the clathrin triskelion structural component; the light chain (CLC1) is thought to regulate function" |
| 2006 | YGL207W | SPT16 SGDID:S000003175, Chr VII from 98973-102080, Verified ORF, "Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), facilitates RNA Polymerase II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure" |
| 2007 | YGL208W | SIP2 SGDID:S000003176, Chr VII from 97342-98589, Verified ORF, "One of three beta subunits of the Snf1 serine/threonine protein kinase complex involved in the response to glucose starvation; null mutants exhibit accelerated aging; N-myristoylprotein localized to the cytoplasm and the plasma membrane" |
| 2008 | YGL209W | MIG2 SGDID:S000003177, Chr VII from 95862-97010, Verified ORF, "Protein containing zinc fingers, involved in repression, along with Mig1p, of SUC2 (invertase) expression by high levels of glucose; binds to Mig1p-binding sites in SUC2 promoter" |
| 2009 | YGL210W | YPT32 SGDID:S000003178, Chr VII from 93797-94465, Verified ORF, "GTPase of the Ypt/Rab family, very similar to Ypt31p; involved in the exocytic pathway; mediates intra-Golgi traffic or the budding of post-Golgi vesicles from the trans-Golgi" |
| 2010 | YGL211W | NCS6 SGDID:S000003179, Chr VII from 92516-93595, Verified ORF, "Protein required for thiolation of the uridine at the wobble position of Gln, Lys, and Glu tRNAs; has a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae" |
| 2011 | YGL212W | VAM7 SGDID:S000003180, Chr VII from 91436-92386, Verified ORF, "Component of the vacuole SNARE complex involved in vacuolar morphogenesis; SNAP-25 homolog; functions with a syntaxin homolog Vam3p in vacuolar protein trafficking" |
| 2012 | YGL213C | SKI8 SGDID:S000003181, Chr VII from 91251-90058, reverse complement, Verified ORF, "Protein involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs as well as double-strand break formation during meiotic recombination; required for repressing propagation of dsRNA viruses" |
| 2013 | YGL215W | CLG1 SGDID:S000003183, Chr VII from 87980-89338, Verified ORF, "Cyclin-like protein that interacts with Pho85p; has sequence similarity to G1 cyclins PCL1 and PCL2" |
| 2014 | YGL216W | KIP3 SGDID:S000003184, Chr VII from 84884-87301, Verified ORF, "Kinesin-related motor protein involved in mitotic spindle positioning" |
| 2015 | YGL219C | MDM34 SGDID:S000003187, Chr VII from 84256-82877, reverse complement, Verified ORF, "Mitochondrial outer membrane protein, required for normal mitochondrial morphology and inheritance; localizes to dots on the mitochondrial surface near mtDNA nucleoids; interacts genetically with MDM31 and MDM32" |
| 2016 | YGL220W | FRA2 SGDID:S000003188, Chr VII from 82373-82735, Uncharacterized ORF, "Protein involved in negative regulation of transcription of iron regulon; forms an iron independent complex with Fra2p, Grx3p, and Grx4p; null mutant fails to repress iron regulon and is sensitive to nickel" |
| 2017 | YGL221C | NIF3 SGDID:S000003189, Chr VII from 82291-81425, reverse complement, Verified ORF, "Protein of unknown function, similar to Listeria monocytogenes major sigma factor (rpoD gene product); the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2018 | YGL222C | EDC1 SGDID:S000003190, Chr VII from 81185-80658, reverse complement, Verified ORF, "RNA-binding protein, activates mRNA decapping directly by binding to the mRNA substrate and enhancing the activity of the decapping proteins Dcp1p and Dcp2p" |
| 2019 | YGL223C | COG1 SGDID:S000003191, Chr VII from 80364-79111, reverse complement, Verified ORF, "Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" |
| 2020 | YGL224C | SDT1 SGDID:S000003192, Chr VII from 78856-78014, reverse complement, Verified ORF, "Pyrimidine nucleotidase; overexpression suppresses the 6-AU sensitivity of transcription elongation factor S-II, as well as resistance to other pyrimidine derivatives" |
| 2021 | YGL225W | VRG4 SGDID:S000003193, Chr VII from 76893-77906, Verified ORF, "Golgi GDP-mannose transporter; regulates Golgi function and glycosylation in Golgi" |
| 2022 | YGL226C-A | OST5 SGDID:S000003194, Chr VII from 73157-73137,72987-72748, reverse complement, Verified ORF, "Zeta subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins" |
| 2023 | YGL226W | YGL226W SGDID:S000003195, Chr VII from 73339-73710, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; YGL226W is synthetically sick with cdc13-1" |
| 2024 | YGL227W | VID30 SGDID:S000003196, Chr VII from 69671-72547, Verified ORF, "Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); shifts the balance of nitrogen metabolism toward the production of glutamate; localized to the nucleus and the cytoplasm" |
| 2025 | YGL228W | SHE10 SGDID:S000003197, Chr VII from 67598-69331, Verified ORF, "Putative glycosylphosphatidylinositol (GPI)-anchored protein of unknown function; overexpression causes growth arrest" |
| 2026 | YGL229C | SAP4 SGDID:S000003198, Chr VII from 66959-64503, reverse complement, Verified ORF, "Protein required for function of the Sit4p protein phosphatase, member of a family of similar proteins that form complexes with Sit4p, including Sap155p, Sap185p, and Sap190p" |
| 2027 | YGL230C | YGL230C SGDID:S000003199, Chr VII from 64215-63772, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene" |
| 2028 | YGL231C | YGL231C SGDID:S000003200, Chr VII from 63620-63048, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum" |
| 2029 | YGL232W | TAN1 SGDID:S000003201, Chr VII from 62075-62131,62190-63002, Verified ORF, "Putative tRNA acetyltransferase, RNA-binding protein required for the formation of the modified nucleoside N(4)-acetylcytidine in serine and leucine tRNAs but not required for the same modification in 18S rRNA" |
| 2030 | YGL233W | SEC15 SGDID:S000003202, Chr VII from 59122-61854, Verified ORF, "Essential 113kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which mediates polarized targeting of vesicles to active sites of exocytosis; Sec15p associates with Sec4p and vesicles" |
| 2031 | YGL234W | ADE5,7 SGDID:S000003203, Chr VII from 56482-58890, Verified ORF, "Bifunctional enzyme of the 'de novo' purine nucleotide biosynthetic pathway, contains aminoimidazole ribotide synthetase and glycinamide ribotide synthetase activities" |
| 2032 | YGL235W | YGL235W SGDID:S000003204, Chr VII from 55279-55815, Uncharacterized ORF, "Putative protein of unknown function; potential Cdc28p substrate; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2" |
| 2033 | YGL236C | MTO1 SGDID:S000003205, Chr VII from 55796-53787, reverse complement, Verified ORF, "Mitochondrial protein, forms a heterodimer complex with Mss1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; required for respiration in paromomycin-resistant 15S rRNA mutants" |
| 2034 | YGL237C | HAP2 SGDID:S000003206, Chr VII from 53528-52731, reverse complement, Verified ORF, "Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; contains sequences sufficient for both complex assembly and DNA binding" |
| 2035 | YGL238W | CSE1 SGDID:S000003207, Chr VII from 49552-52434, Verified ORF, "Nuclear envelope protein that mediates the nuclear export of importin alpha (Srp1p), homolog of metazoan CAS protein, required for accurate chromosome segregation" |
| 2036 | YGL240W | DOC1 SGDID:S000003209, Chr VII from 48613-49365, Verified ORF, "Processivity factor required for the ubiquitination activity of the anaphase promoting complex (APC), mediates the activity of the APC by contributing to substrate recognition; involved in cyclin proteolysis" |
| 2037 | YGL241W | KAP114 SGDID:S000003210, Chr VII from 45445-48459, Verified ORF, "Karyopherin, responsible for nuclear import of Spt15p, histones H2A and H2B, and Nap1p; amino terminus shows similarity to those of other importins, particularly Cse1p; localization is primarily nuclear" |
| 2038 | YGL242C | YGL242C SGDID:S000003211, Chr VII from 45197-44652, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; deletion mutant is viable" |
| 2039 | YGL243W | TAD1 SGDID:S000003212, Chr VII from 43307-44509, Verified ORF, "tRNA-specific adenosine deaminase, deaminates adenosine-37 to inosine in tRNA-Ala" |
| 2040 | YGL244W | RTF1 SGDID:S000003213, Chr VII from 41498-43174, Verified ORF, "Subunit of the RNA polymerase II-associated Paf1 complex; directly or indirectly regulates DNA-binding properties of Spt15p and relative activities of different TATA elements; involved in telomere maintenance" |
| 2041 | YGL245W | GUS1 SGDID:S000003214, Chr VII from 39023-41149, Verified ORF, "Glutamyl-tRNA synthetase (GluRS), forms a complex with methionyl-tRNA synthetase (Mes1p) and Arc1p; complex formation increases the catalytic efficiency of both tRNA synthetases and ensures their correct localization to the cytoplasm" |
| 2042 | YGL246C | RAI1 SGDID:S000003215, Chr VII from 38780-37617, reverse complement, Verified ORF, "Nuclear protein that binds to and stabilizes the exoribonuclease Rat1p, required for pre-rRNA processing" |
| 2043 | YGL247W | BRR6 SGDID:S000003216, Chr VII from 36933-37526, Verified ORF, "Essential nuclear envelope integral membrane protein required for nuclear transport; depletion alters nucleoporin distribution and nuclear envelope morphology, suggesting a role in the spatial organization of nuclear pores" |
| 2044 | YGL248W | PDE1 SGDID:S000003217, Chr VII from 35653-36762, Verified ORF, "Low-affinity cyclic AMP phosphodiesterase, controls glucose and intracellular acidification-induced cAMP signaling, target of the cAMP-protein kinase A (PKA) pathway; glucose induces transcription and inhibits translation" |
| 2045 | YGL249W | ZIP2 SGDID:S000003218, Chr VII from 33098-35212, Verified ORF, "Meiosis-specific protein involved in normal synaptonemal complex formation and pairing between homologous chromosomes during meiosis" |
| 2046 | YGL250W | RMR1 SGDID:S000003219, Chr VII from 31910-32635, Verified ORF, "Protein required for meiotic recombination and gene conversion; null mutant displays reduced PIS1 expression and growth defects on non-fermentable carbon sources and minimal media; GFP-fusion protein localizes to both cytoplasm and nucleus" |
| 2047 | YGL251C | HFM1 SGDID:S000003220, Chr VII from 31636-31579,31426-27921, reverse complement, Verified ORF, "Meiosis specific DNA helicase involved in the conversion of double-stranded breaks to later recombination intermediates and in crossover control; catalyzes the unwinding of Holliday junctions; has ssDNA and dsDNA stimulated ATPase activity" |
| 2048 | YGL252C | RTG2 SGDID:S000003221, Chr VII from 27484-25718, reverse complement, Verified ORF, "Sensor of mitochondrial dysfunction; regulates the subcellular location of Rtg1p and Rtg3p, transcriptional activators of the retrograde (RTG) and TOR pathways; Rtg2p is inhibited by the phosphorylated form of Mks1p" |
| 2049 | YGL253W | HXK2 SGDID:S000003222, Chr VII from 23935-25395, Verified ORF, "Hexokinase isoenzyme 2 that catalyzes phosphorylation of glucose in the cytosol; predominant hexokinase during growth on glucose; functions in the nucleus to repress expression of HXK1 and GLK1 and to induce expression of its own gene" |
| 2050 | YGL254W | FZF1 SGDID:S000003223, Chr VII from 22304-23203, Verified ORF, "Transcription factor involved in sulfite metabolism, sole identified regulatory target is SSU1, overexpression suppresses sulfite-sensitivity of many unrelated mutants due to hyperactivation of SSU1, contains five zinc fingers" |
| 2051 | YGL255W | ZRT1 SGDID:S000003224, Chr VII from 20978-22108, Verified ORF, "High-affinity zinc transporter of the plasma membrane, responsible for the majority of zinc uptake; transcription is induced under low-zinc conditions by the Zap1p transcription factor" |
| 2052 | YGL256W | ADH4 SGDID:S000003225, Chr VII from 15159-16307, Verified ORF, "Alcohol dehydrogenase isoenzyme type IV, dimeric enzyme demonstrated to be zinc-dependent despite sequence similarity to iron-activated alcohol dehydrogenases; transcription is induced in response to zinc deficiency" |
| 2053 | YGL257C | MNT2 SGDID:S000003226, Chr VII from 14157-12481, reverse complement, Verified ORF, "Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans" |
| 2054 | YGL258W | VEL1 SGDID:S000003227, Chr VII from 11110-11730, Verified ORF, "Protein of unknown function; highly induced in zinc-depleted conditions and has increased expression in NAP1 deletion mutants" |
| 2055 | YGL258W-A | YGL258W-A SGDID:S000007607, Chr VII from 9162-9395, Uncharacterized ORF, "Putative protein of unknown function" |
| 2056 | YGL259W | YPS5 SGDID:S000003228, Chr VII from 8470-8967, Uncharacterized ORF, "Protein with similarity to GPI-anchored aspartic proteases such as Yap1p and Yap3p" |
| 2057 | YGL260W | YGL260W SGDID:S000003229, Chr VII from 6860-7090, Uncharacterized ORF, "Putative protein of unknown function; transcription is significantly increased in a NAP1 deletion background; deletion mutant has increased accumulation of nickel and selenium" |
| 2058 | YGL261C | YGL261C SGDID:S000003230, Chr VII from 6652-6290, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; mRNA expression appears to be regulated by SUT1 and UPC2" |
| 2059 | YGL262W | YGL262W SGDID:S000003231, Chr VII from 5312-5839, Uncharacterized ORF, "Putative protein of unknown function; null mutant displays elevated sensitivity to expression of a mutant huntingtin fragment or of alpha-synuclein; YGL262W is not an essential gene" |
| 2060 | YGL263W | COS12 SGDID:S000003232, Chr VII from 2790-3932, Verified ORF, "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" |
| 2061 | YGR001C | YGR001C SGDID:S000003233, Chr VII from 498038-498004,497941-497463,497369-497137, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with similarity to methyltransferase family members; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; required for replication of Brome mosaic virus in S. cerevisiae" |
| 2062 | YGR002C | SWC4 SGDID:S000003234, Chr VII from 499910-498480, reverse complement, Verified ORF, "Component of the Swr1p complex that incorporates Htz1p into chromatin; component of the NuA4 histone acetyltransferase complex" |
| 2063 | YGR003W | CUL3 SGDID:S000003235, Chr VII from 500136-502370, Verified ORF, "Ubiquitin-protein ligase, member of the cullin family with similarity to Cdc53p and human CUL3; required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21" |
| 2064 | YGR004W | PEX31 SGDID:S000003236, Chr VII from 502942-504330, Verified ORF, "Peroxisomal integral membrane protein, involved in negative regulation of peroxisome size; partially functionally redundant with Pex30p and Pex32p; probably acts at a step downstream of steps mediated by Pex28p and Pex29p" |
| 2065 | YGR005C | TFG2 SGDID:S000003237, Chr VII from 505863-504661, reverse complement, Verified ORF, "TFIIF (Transcription Factor II) middle subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP30" |
| 2066 | YGR006W | PRP18 SGDID:S000003238, Chr VII from 506074-506829, Verified ORF, "Splicing factor involved in the positioning of the 3' splice site during the second catalytic step of splicing, part of snRNP U5, interacts with Slu7p" |
| 2067 | YGR007W | MUQ1 SGDID:S000003239, Chr VII from 506973-507944, Verified ORF, "Choline phosphate cytidylyltransferase, catalyzes the second step of phosphatidylethanolamine biosynthesis; involved in the maintenance of plasma membrane; similar to mammalian CTP: phosphocholine cytidylyl-transferases" |
| 2068 | YGR008C | STF2 SGDID:S000003240, Chr VII from 508368-508114, reverse complement, Verified ORF, "Protein involved in regulation of the mitochondrial F1F0-ATP synthase; Stf1p and Stf2p may act as stabilizing factors that enhance inhibitory action of the Inh1p protein" |
| 2069 | YGR009C | SEC9 SGDID:S000003241, Chr VII from 511006-509051, reverse complement, Verified ORF, "t-SNARE protein important for fusion of secretory vesicles with the plasma membrane; similar to but not functionally redundant with Spo20p; SNAP-25 homolog" |
| 2070 | YGR010W | NMA2 SGDID:S000003242, Chr VII from 511549-512736, Verified ORF, "Nicotinic acid mononucleotide adenylyltransferase, involved in de novo and salvage synthesis of NAD(+)" |
| 2071 | YGR012W | YGR012W SGDID:S000003244, Chr VII from 513163-514344, Verified ORF, "Putative cysteine synthase, localized to the mitochondrial outer membrane" |
| 2072 | YGR013W | SNU71 SGDID:S000003245, Chr VII from 514558-516420, Verified ORF, "Component of U1 snRNP required for mRNA splicing via spliceosome; yeast specific, no metazoan counterpart" |
| 2073 | YGR014W | MSB2 SGDID:S000003246, Chr VII from 516947-520867, Verified ORF, "Mucin family member involved in the Cdc42p- and MAP kinase-dependent filamentous growth signaling pathway; also functions as an osmosensor in parallel to the Sho1p-mediated pathway; potential Cdc28p substrate" |
| 2074 | YGR015C | YGR015C SGDID:S000003247, Chr VII from 522080-521094, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion" |
| 2075 | YGR016W | YGR016W SGDID:S000003248, Chr VII from 522265-522837, Uncharacterized ORF, "Putative protein of unknown function" |
| 2076 | YGR017W | YGR017W SGDID:S000003249, Chr VII from 523791-524684, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm" |
| 2077 | YGR019W | UGA1 SGDID:S000003251, Chr VII from 525233-526648, Verified ORF, "Gamma-aminobutyrate (GABA) transaminase (4-aminobutyrate aminotransferase) involved in the 4-aminobutyrate and glutamate degradation pathways; required for normal oxidative stress tolerance and nitrogen utilization" |
| 2078 | YGR020C | VMA7 SGDID:S000003252, Chr VII from 527333-526977, reverse complement, Verified ORF, "Subunit F of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane" |
| 2079 | YGR021W | YGR021W SGDID:S000003253, Chr VII from 527636-528508, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2080 | YGR023W | MTL1 SGDID:S000003255, Chr VII from 529268-530923, Verified ORF, "Protein with both structural and functional similarity to Mid2p, which is a plasma membrane sensor required for cell integrity signaling during pheromone-induced morphogenesis; suppresses rgd1 null mutations" |
| 2081 | YGR024C | THG1 SGDID:S000003256, Chr VII from 532600-531887, reverse complement, Verified ORF, "tRNAHis guanylyltransferase, adds a guanosine residue to the 5' end of tRNAHis after transcription and RNase P cleavage; couples nuclear division and migration to cell budding and cytokinesis; essential enzyme conserved among eukaryotes" |
| 2082 | YGR026W | YGR026W SGDID:S000003258, Chr VII from 532989-533825, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery" |
| 2083 | YGR027C | RPS25A SGDID:S000003259, Chr VII from 534462-534136, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Bp and has similarity to rat S25 ribosomal protein" |
| 2084 | YGR027W-A | YGR027W-A SGDID:S000007405, Chr VII from 536061-537383, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 2085 | YGR027W-B | YGR027W-B SGDID:S000007406, Chr VII from 536061-537365,537367-541329, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 2086 | YGR028W | MSP1 SGDID:S000003260, Chr VII from 542207-543295, Verified ORF, "Mitochondrial protein involved in sorting of proteins in the mitochondria; putative membrane-spanning ATPase" |
| 2087 | YGR029W | ERV1 SGDID:S000003261, Chr VII from 543557-543642,543726-544209, Verified ORF, "Flavin-linked sulfhydryl oxidase of the mitochondrial intermembrane space (IMS), oxidizes Mia40p as part of a disulfide relay system that promotes IMS retention of imported proteins; ortholog of human hepatopoietin (ALR)" |
| 2088 | YGR030C | POP6 SGDID:S000003262, Chr VII from 546161-545685, reverse complement, Verified ORF, "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" |
| 2089 | YGR031C-A | NAG1 SGDID:S000028636, Chr VII from 547304-546813, reverse complement, Verified ORF, "Protein involved in yeast cell wall biogenesis; localizes to the cell periphery; production of Nag1p is dependent upon the presence of Slt2p and Rlm1p; null is hypersensitive to calcofluor white; overlaps the uncharacterized ORF YGR031W" |
| 2090 | YGR031W | YGR031W SGDID:S000003263, Chr VII from 546445-547473, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2091 | YGR032W | GSC2 SGDID:S000003264, Chr VII from 548268-553955, Verified ORF, "Catalytic subunit of 1,3-beta-glucan synthase, involved in formation of the inner layer of the spore wall; activity positively regulated by Rho1p and negatively by Smk1p; has similarity to an alternate catalytic subunit, Fks1p (Gsc1p)" |
| 2092 | YGR033C | TIM21 SGDID:S000003265, Chr VII from 554971-554252, reverse complement, Verified ORF, "Constituent of the mitochondrial inner membrane presequence translocase (TIM23 complex); may regulate protein import by binding to both the translocase of the outer membrane (TOM) and presequence-associated motor (PAM) complexes" |
| 2093 | YGR034W | RPL26B SGDID:S000003266, Chr VII from 555816-555834,556312-556676, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Ap and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA" |
| 2094 | YGR035C | YGR035C SGDID:S000003267, Chr VII from 557426-557076, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, potential Cdc28p substrate; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance" |
| 2095 | YGR035W-A | YGR035W-A SGDID:S000028827, Chr VII from 557569-557790, Uncharacterized ORF, "Putative protein of unknown function" |
| 2096 | YGR036C | CAX4 SGDID:S000003268, Chr VII from 558872-558153, reverse complement, Verified ORF, "Dolichyl pyrophosphate (Dol-P-P) phosphatase with a luminally oriented active site in the ER, cleaves the anhydride linkage in Dol-P-P, required for Dol-P-P-linked oligosaccharide intermediate synthesis and protein N-glycosylation" |
| 2097 | YGR037C | ACB1 SGDID:S000003269, Chr VII from 559998-559735, reverse complement, Verified ORF, "Acyl-CoA-binding protein, transports newly synthesized acyl-CoA esters from fatty acid synthetase (Fas1p-Fas2p) to acyl-CoA-consuming processes" |
| 2098 | YGR038C-A | YGR038C-A SGDID:S000007407, Chr VII from 567471-566149, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 2099 | YGR038C-B | YGR038C-B SGDID:S000007408, Chr VII from 567471-566167,566165-562203, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 2100 | YGR038W | ORM1 SGDID:S000003270, Chr VII from 560686-561354, Verified ORF, "Evolutionarily conserved protein with similarity to Orm2p, required for resistance to agents that induce the unfolded protein response; human ortholog is located in the endoplasmic reticulum" |
| 2101 | YGR040W | KSS1 SGDID:S000003272, Chr VII from 575402-576508, Verified ORF, "Mitogen-activated protein kinase (MAPK) involved in signal transduction pathways that control filamentous growth and pheromone response; the KSS1 gene is nonfunctional in S288C strains and functional in W303 strains" |
| 2102 | YGR041W | BUD9 SGDID:S000003273, Chr VII from 577491-579134, Verified ORF, "Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the distal pole" |
| 2103 | YGR042W | YGR042W SGDID:S000003274, Chr VII from 579480-580295, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus" |
| 2104 | YGR043C | YGR043C SGDID:S000003275, Chr VII from 581440-580439, reverse complement, Uncharacterized ORF, "Protein of unknown function; transcription is repressed by Mot1p and induced by alpha-factor and during diauxic shift; null mutant non-quiescent cells exhibit reduced reproductive capacity" |
| 2105 | YGR044C | RME1 SGDID:S000003276, Chr VII from 583896-582994, reverse complement, Verified ORF, "Zinc finger protein involved in control of meiosis; prevents meiosis by repressing IME1 expression and promotes mitosis by activating CLN2 expression; directly repressed by a1-a2 regulator; mediates cell type control of sporulation" |
| 2106 | YGR046W | TAM41 SGDID:S000003278, Chr VII from 584899-586056, Verified ORF, "Mitochondrial protein involved in protein import into the mitochondrial matrix; maintains the functional integrity of the TIM23 protein translocator complex; viability of null mutant is strain-dependent; mRNA is targeted to the bud" |
| 2107 | YGR047C | TFC4 SGDID:S000003279, Chr VII from 589473-586396, reverse complement, Verified ORF, "One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA domain of TFIIIC that binds BoxA DNA promoter sites of tRNA and similar genes; has TPR motifs; human homolog is TFIIIC-102" |
| 2108 | YGR048W | UFD1 SGDID:S000003280, Chr VII from 589830-590915, Verified ORF, "Protein that interacts with Cdc48p and Npl4p, involved in recognition of polyubiquitinated proteins and their presentation to the 26S proteasome for degradation; involved in transporting proteins from the ER to the cytosol" |
| 2109 | YGR049W | SCM4 SGDID:S000003281, Chr VII from 591318-591881, Verified ORF, "Potential regulatory effector of CDC4 function, suppresses a temperature-sensitive allele of CDC4, tripartite protein structure in which a charged region separates two uncharged domains, not essential for mitosis or meiosis" |
| 2110 | YGR052W | FMP48 SGDID:S000003284, Chr VII from 593600-594709, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; induced by treatment with 8-methoxypsoralen and UVA irradiation" |
| 2111 | YGR053C | YGR053C SGDID:S000003285, Chr VII from 595841-594990, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 2112 | YGR054W | YGR054W SGDID:S000003286, Chr VII from 596697-598625, Verified ORF, "Eukaryotic initiation factor (eIF) 2A; associates specifically with both 40S subunits and 80 S ribosomes, and interacts genetically with both eIF5b and eIF4E; homologous to mammalian eIF2A" |
| 2113 | YGR055W | MUP1 SGDID:S000003287, Chr VII from 599421-601145, Verified ORF, "High affinity methionine permease, integral membrane protein with 13 putative membrane-spanning regions; also involved in cysteine uptake" |
| 2114 | YGR056W | RSC1 SGDID:S000003288, Chr VII from 601665-604451, Verified ORF, "Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; contains two essential bromodomains, a bromo-adjacent homology (BAH) domain, and an AT hook" |
| 2115 | YGR057C | LST7 SGDID:S000003289, Chr VII from 605505-604777, reverse complement, Verified ORF, "Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface" |
| 2116 | YGR058W | PEF1 SGDID:S000003290, Chr VII from 606140-607147, Verified ORF, "Penta-EF-hand protein required for polar bud growth and cell wall abscission; binds calcium and zinc with different affinity; localizes to bud site in G1, bud neck in G2" |
| 2117 | YGR059W | SPR3 SGDID:S000003291, Chr VII from 607567-609105, Verified ORF, "Sporulation-specific homolog of the yeast CDC3/10/11/12 family of bud neck microfilament genes; septin protein involved in sporulation; regulated by ABFI" |
| 2118 | YGR060W | ERG25 SGDID:S000003292, Chr VII from 610568-611497, Verified ORF, "C-4 methyl sterol oxidase, catalyzes the first of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants accumulate the sterol intermediate 4,4-dimethylzymosterol" |
| 2119 | YGR061C | ADE6 SGDID:S000003293, Chr VII from 615969-611893, reverse complement, Verified ORF, "Formylglycinamidine-ribonucleotide (FGAM)-synthetase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway" |
| 2120 | YGR062C | COX18 SGDID:S000003294, Chr VII from 617282-616332, reverse complement, Verified ORF, "Mitochondrial integral inner membrane protein required for membrane insertion of C-terminus of Cox2p; interacts genetically and physically with Mss2p and Pnt1p; similar to S. cerevisiae Oxa1, N. crassa Oxa2p, and E. coli YidC" |
| 2121 | YGR063C | SPT4 SGDID:S000003295, Chr VII from 617828-617520, reverse complement, Verified ORF, "Protein that forms a complex with Spt5p and mediates both activation and inhibition of transcription elongation, and plays a role in pre-mRNA processing; in addition, Spt4p is involved in kinetochore function and gene silencing" |
| 2122 | YGR065C | VHT1 SGDID:S000003297, Chr VII from 619862-618081, reverse complement, Verified ORF, "High-affinity plasma membrane H+-biotin (vitamin H) symporter; mutation results in fatty acid auxotrophy; 12 transmembrane domain containing major facilitator subfamily member; mRNA levels negatively regulated by iron deprivation and biotin" |
| 2123 | YGR066C | YGR066C SGDID:S000003298, Chr VII from 621803-620925, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 2124 | YGR067C | YGR067C SGDID:S000003299, Chr VII from 624790-622406, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; contains a zinc finger motif similar to that of Adr1p" |
| 2125 | YGR068C | YGR068C SGDID:S000003300, Chr VII from 627088-625328, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YGR068C is not an essential gene." |
| 2126 | YGR070W | ROM1 SGDID:S000003302, Chr VII from 627810-631277, Verified ORF, "GDP/GTP exchange protein (GEP) for Rho1p; mutations are synthetically lethal with mutations in rom2, which also encodes a GEP" |
| 2127 | YGR071C | YGR071C SGDID:S000003303, Chr VII from 634067-631485, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; deletion mutant has increased glycogen accumulation; green fluorescent protein (GFP)-fusion protein localizes to the nucleus" |
| 2128 | YGR072W | UPF3 SGDID:S000003304, Chr VII from 634308-635471, Verified ORF, "Component of the nonsense-mediated mRNA decay (NMD) pathway, along with Nam7p and Nmd2p; involved in decay of mRNA containing nonsense codons; involved in telomere maintenance" |
| 2129 | YGR074W | SMD1 SGDID:S000003306, Chr VII from 635716-636156, Verified ORF, "Core Sm protein Sm D1; part of heteroheptameric complex (with Smb1p, Smd2p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D1" |
| 2130 | YGR075C | PRP38 SGDID:S000003307, Chr VII from 636879-636151, reverse complement, Verified ORF, "Unique component of the U4/U6.U5 tri-snRNP particle, required for conformational changes which result in the catalytic activation of the spliceosome; dispensible for spliceosome assembly" |
| 2131 | YGR076C | MRPL25 SGDID:S000003308, Chr VII from 637581-637108, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 2132 | YGR077C | PEX8 SGDID:S000003309, Chr VII from 639517-637748, reverse complement, Verified ORF, "Intraperoxisomal organizer of the peroxisomal import machinery, tightly associated with the lumenal face of the peroxisomal membrane, essential for peroxisome biogenesis, binds PTS1-signal receptor Pex5p" |
| 2133 | YGR078C | PAC10 SGDID:S000003310, Chr VII from 640375-639776, reverse complement, Verified ORF, "Part of the heteromeric co-chaperone GimC/prefoldin complex, which promotes efficient protein folding" |
| 2134 | YGR079W | YGR079W SGDID:S000003311, Chr VII from 640724-641836, Uncharacterized ORF, "Putative protein of unknown function; YGR079W is not an essential gene" |
| 2135 | YGR080W | TWF1 SGDID:S000003312, Chr VII from 642014-643012, Verified ORF, "Twinfilin, highly conserved actin monomer-sequestering protein involved in regulation of the cortical actin cytoskeleton, composed of two cofilin-like regions, localizes actin monomers to sites of rapid filament assembly" |
| 2136 | YGR081C | SLX9 SGDID:S000003313, Chr VII from 643784-643152, reverse complement, Verified ORF, "Protein required for pre-rRNA processing; associated with the 90S pre-ribosome and 43S small ribosomal subunit precursor; interacts with U3 snoRNA; deletion mutant has synthetic fitness defect with an sgs1 deletion mutant" |
| 2137 | YGR082W | TOM20 SGDID:S000003314, Chr VII from 644048-644599, Verified ORF, "Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins" |
| 2138 | YGR083C | GCD2 SGDID:S000003315, Chr VII from 646819-644864, reverse complement, Verified ORF, "Delta subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression" |
| 2139 | YGR084C | MRP13 SGDID:S000003316, Chr VII from 648146-647127, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 2140 | YGR085C | RPL11B SGDID:S000003317, Chr VII from 648911-648387, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Ap; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11" |
| 2141 | YGR086C | PIL1 SGDID:S000003318, Chr VII from 650621-649602, reverse complement, Verified ORF, "Primary component of eisosomes, which are large immobile cell cortex structures associated with endocytosis; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways; detected in phosphorylated state in mitochondria" |
| 2142 | YGR087C | PDC6 SGDID:S000003319, Chr VII from 652985-651294, reverse complement, Verified ORF, "Minor isoform of pyruvate decarboxylase, decarboxylates pyruvate to acetaldehyde, involved in amino acid catabolism; transcription is glucose- and ethanol-dependent, and is strongly induced during sulfur limitation" |
| 2143 | YGR088W | CTT1 SGDID:S000003320, Chr VII from 654638-656326, Verified ORF, "Cytosolic catalase T, has a role in protection from oxidative damage by hydrogen peroxide" |
| 2144 | YGR089W | NNF2 SGDID:S000003321, Chr VII from 656964-659774, Verified ORF, "Protein that exhibits physical and genetic interactions with Rpb8p, which is a subunit of RNA polymerases I, II, and III; computational analysis of large-scale protein-protein interaction data suggests a role in chromosome segregation" |
| 2145 | YGR090W | UTP22 SGDID:S000003322, Chr VII from 662362-666075, Verified ORF, "Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data" |
| 2146 | YGR091W | PRP31 SGDID:S000003323, Chr VII from 666345-667829, Verified ORF, "Splicing factor, component of the U4/U6-U5 snRNP complex" |
| 2147 | YGR092W | DBF2 SGDID:S000003324, Chr VII from 668193-669911, Verified ORF, "Ser/Thr kinase involved in transcription and stress response; functions as part of a network of genes in exit from mitosis; localization is cell cycle regulated; activated by Cdc15p during the exit from mitosis" |
| 2148 | YGR093W | YGR093W SGDID:S000003325, Chr VII from 670392-671915, Uncharacterized ORF, "Putative debranching enzyme associated ribonuclease; green fluorescent protein (GFP)-fusion protein localizes to the nucleus" |
| 2149 | YGR094W | VAS1 SGDID:S000003326, Chr VII from 672190-675504, Verified ORF, "Mitochondrial and cytoplasmic valyl-tRNA synthetase" |
| 2150 | YGR095C | RRP46 SGDID:S000003327, Chr VII from 676346-675675, reverse complement, Verified ORF, "Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex" |
| 2151 | YGR096W | TPC1 SGDID:S000003328, Chr VII from 676625-677569, Verified ORF, "Mitochondrial membrane transporter that mediates uptake of the essential cofactor thiamine pyrophosphate (ThPP) into mitochondria; expression appears to be regulated by carbon source; member of the mitochondrial carrier family" |
| 2152 | YGR097W | ASK10 SGDID:S000003329, Chr VII from 678699-682139, Verified ORF, "Component of the RNA polymerase II holoenzyme, phosphorylated in response to oxidative stress; has a role in destruction of Ssn8p, which relieves repression of stress-response genes" |
| 2153 | YGR098C | ESP1 SGDID:S000003330, Chr VII from 687462-682570, reverse complement, Verified ORF, "Separase, a caspase-like cysteine protease that promotes sister chromatid separation by mediating dissociation of the cohesin Scc1p from chromatin; inhibits protein phosphatase 2A-Cdc55p to promote mitotic exit; inhibited by Pds1p" |
| 2154 | YGR099W | TEL2 SGDID:S000003331, Chr VII from 687903-689969, Verified ORF, "Essential DNA-binding protein specific to single-stranded yeast telomeric DNA repeats, required for telomere length regulation and telomere position effect" |
| 2155 | YGR100W | MDR1 SGDID:S000003332, Chr VII from 690249-693101, Verified ORF, "Cytoplasmic GTPase-activating protein for Ypt/Rab transport GTPases Ypt6p, Ypt31p and Sec4p; involved in recycling of internalized proteins and regulation of Golgi secretory function" |
| 2156 | YGR101W | PCP1 SGDID:S000003333, Chr VII from 693367-694407, Verified ORF, "Mitochondrial serine protease required for the processing of various mitochondrial proteins and maintenance of mitochondrial DNA and morphology; belongs to the rhomboid-GlpG superfamily of intramembrane peptidases" |
| 2157 | YGR102C | YGR102C SGDID:S000003334, Chr VII from 695139-694588, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; transposon insertion mutant is salt sensitive and deletion mutant has growth defects; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2158 | YGR103W | NOP7 SGDID:S000003335, Chr VII from 695421-697238, Verified ORF, "Nucleolar protein involved in rRNA processing and 60S ribosomal subunit biogenesis; constituent of several different pre-ribosomal particles; required for exit from G0 and the initiation of cell proliferation" |
| 2159 | YGR104C | SRB5 SGDID:S000003336, Chr VII from 698372-697449, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation; involved in telomere maintenance" |
| 2160 | YGR105W | VMA21 SGDID:S000003337, Chr VII from 698603-698836, Verified ORF, "Integral membrane protein that is required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the yeast endoplasmic reticulum (ER)" |
| 2161 | YGR106C | YGR106C SGDID:S000003338, Chr VII from 699790-698993, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuolar memebrane" |
| 2162 | YGR108W | CLB1 SGDID:S000003340, Chr VII from 703640-705055, Verified ORF, "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome" |
| 2163 | YGR109C | CLB6 SGDID:S000003341, Chr VII from 706505-705363, reverse complement, Verified ORF, "B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1" |
| 2164 | YGR109W-A | YGR109W-A SGDID:S000007346, Chr VII from 707614-708486, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 2165 | YGR109W-B | YGR109W-B SGDID:S000007347, Chr VII from 707614-708463,708465-712258, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 2166 | YGR110W | YGR110W SGDID:S000003342, Chr VII from 713713-715050, Uncharacterized ORF, "Putative protein of unknown function; transcription is increased in response to genotoxic stress; plays a role in restricting Ty1 transposition" |
| 2167 | YGR111W | YGR111W SGDID:S000003343, Chr VII from 715832-717034, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus" |
| 2168 | YGR112W | SHY1 SGDID:S000003344, Chr VII from 717362-718531, Verified ORF, "Mitochondrial inner membrane protein required for assembly of cytochrome c oxidase (complex IV); associates with complex IV assembly intermediates and complex III/complex IV supercomplexes; similar to human SURF1 involved in Leigh Syndrome" |
| 2169 | YGR113W | DAM1 SGDID:S000003345, Chr VII from 718897-719928, Verified ORF, "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; Ipl1p target for regulating kinetochore-MT attachments" |
| 2170 | YGR116W | SPT6 SGDID:S000003348, Chr VII from 720413-724768, Verified ORF, "Transcription elongation factor required for the maintenance of chromatin structure during transcription in order to inhibit transcription from promoters within the coding region" |
| 2171 | YGR117C | YGR117C SGDID:S000003349, Chr VII from 726483-725053, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 2172 | YGR118W | RPS23A SGDID:S000003350, Chr VII from 726978-727042,727363-727735, Verified ORF, "Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Bp and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal" |
| 2173 | YGR119C | NUP57 SGDID:S000003351, Chr VII from 729676-728051, reverse complement, Verified ORF, "Nucleoporin, essential subunit of the nuclear pore complex (NPC), functions as the organizing center of an NPC subcomplex containing Nsp1p, Nup49p, Nup57p, and Nic96p" |
| 2174 | YGR120C | COG2 SGDID:S000003352, Chr VII from 730826-730038, reverse complement, Verified ORF, "Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" |
| 2175 | YGR121C | MEP1 SGDID:S000003353, Chr VII from 732932-731454, reverse complement, Verified ORF, "Ammonium permease; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation" |
| 2176 | YGR121W-A | YGR121W-A SGDID:S000028550, Chr VII from 733417-733632, Uncharacterized ORF, "Putative protein of unknown function" |
| 2177 | YGR122W | YGR122W SGDID:S000003354, Chr VII from 733940-735148, Uncharacterized ORF, "Putative protein of unknown function; deletion mutants do not properly process Rim101p and have decreased resistance to rapamycin; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 2178 | YGR123C | PPT1 SGDID:S000003355, Chr VII from 738208-736667, reverse complement, Verified ORF, "Protein serine/threonine phosphatase with similarity to human phosphatase PP5; present in both the nucleus and cytoplasm; expressed during logarithmic growth; computational analyses suggest roles in phosphate metabolism and rRNA processing" |
| 2179 | YGR124W | ASN2 SGDID:S000003356, Chr VII from 739949-741667, Verified ORF, "Asparagine synthetase, isozyme of Asn1p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway" |
| 2180 | YGR125W | YGR125W SGDID:S000003357, Chr VII from 742330-745440, Uncharacterized ORF, "Putative protein of unknown function; deletion mutant has decreased rapamycin resistance but normal wormannin resistance; green fluorescent protein (GFP)-fusion protein localizes to the vacuole" |
| 2181 | YGR126W | YGR126W SGDID:S000003358, Chr VII from 745840-746532, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus and is induced in response to the DNA-damaging agent MMS" |
| 2182 | YGR127W | YGR127W SGDID:S000003359, Chr VII from 746803-747741, Uncharacterized ORF, "Putative protein of unknown function; expression is regulated by Msn2p/Msn4p, indicating a possible role in stress response" |
| 2183 | YGR128C | UTP8 SGDID:S000003360, Chr VII from 750096-747955, reverse complement, Verified ORF, "Nucleolar protein required for export of tRNAs from the nucleus; also copurifies with the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" |
| 2184 | YGR129W | SYF2 SGDID:S000003361, Chr VII from 750405-751052, Verified ORF, "Component of the spliceosome complex involved in pre-mRNA splicing; involved in regulation of cell cycle progression" |
| 2185 | YGR130C | YGR130C SGDID:S000003362, Chr VII from 753849-751399, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; specifically phosphorylated in vitro by mammalian diphosphoinositol pentakisphosphate (IP7)" |
| 2186 | YGR131W | YGR131W SGDID:S000003363, Chr VII from 754731-755255, Uncharacterized ORF, "Protein of unknown function; expression induced in response to ketoconazole; promoter region contains a sterol regulatory element motif, which has been identified as a Upc2p-binding site" |
| 2187 | YGR132C | PHB1 SGDID:S000003364, Chr VII from 756457-755594, reverse complement, Verified ORF, "Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation" |
| 2188 | YGR133W | PEX4 SGDID:S000003365, Chr VII from 756901-757452, Verified ORF, "Peroxisomal ubiquitin conjugating enzyme required for peroxisomal matrix protein import and peroxisome biogenesis" |
| 2189 | YGR134W | CAF130 SGDID:S000003366, Chr VII from 757775-761143, Verified ORF, "Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation" |
| 2190 | YGR135W | PRE9 SGDID:S000003367, Chr VII from 761397-762173, Verified ORF, "Alpha 3 subunit of the 20S proteasome, the only nonessential 20S subunit; may be replaced by the alpha 4 subunit (Pre6p) under stress conditions to create a more active proteasomal isoform" |
| 2191 | YGR136W | LSB1 SGDID:S000003368, Chr VII from 762433-763158, Verified ORF, "Protein containing an N-terminal SH3 domain; binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization" |
| 2192 | YGR138C | TPO2 SGDID:S000003370, Chr VII from 765611-763767, reverse complement, Verified ORF, "Polyamine transport protein specific for spermine; localizes to the plasma membrane; transcription of TPO2 is regulated by Haa1p; member of the major facilitator superfamily" |
| 2193 | YGR140W | CBF2 SGDID:S000003372, Chr VII from 767434-770304, Verified ORF, "Essential kinetochore protein, component of the CBF3 multisubunit complex that binds to the CDEIII region of the centromere; Cbf2p also binds to the CDEII region possibly forming a different multimeric complex, ubiquitinated in vivo" |
| 2194 | YGR141W | VPS62 SGDID:S000003373, Chr VII from 770574-771977, Verified ORF, "Vacuolar protein sorting (VPS) protein required for cytoplasm to vacuole targeting of proteins" |
| 2195 | YGR142W | BTN2 SGDID:S000003374, Chr VII from 772459-773691, Verified ORF, "v-SNARE binding protein that facilitates specific protein retrieval from a late endosome to the Golgi; modulates arginine uptake, possible role in mediating pH homeostasis between the vacuole and plasma membrane H(+)-ATPase" |
| 2196 | YGR143W | SKN1 SGDID:S000003375, Chr VII from 775198-777513, Verified ORF, "Protein involved in sphingolipid biosynthesis; type II membrane protein with similarity to Kre6p" |
| 2197 | YGR144W | THI4 SGDID:S000003376, Chr VII from 780404-781384, Verified ORF, "Thiazole synthase, catalyzes formation of the thiazole moiety of thiamin pyrophosphate; required for thiamine biosynthesis and for mitochondrial genome stability" |
| 2198 | YGR145W | ENP2 SGDID:S000003377, Chr VII from 781772-783895, Verified ORF, "Essential nucleolar protein of unknown function; contains WD repeats, interacts with Mpp10p and Bfr2p, and has homology to Spb1p" |
| 2199 | YGR146C | YGR146C SGDID:S000003378, Chr VII from 784863-784228, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; induced by iron homeostasis transcription factor Aft2p; multicopy suppressor of a temperature sensitive hsf1 mutant; induced by treatment with 8-methoxypsoralen and UVA irradiation" |
| 2200 | YGR146C-A | YGR146C-A SGDID:S000028638, Chr VII from 785442-785281, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 2201 | YGR147C | NAT2 SGDID:S000003379, Chr VII from 786925-786059, reverse complement, Verified ORF, "Protein with an apparent role in acetylation of N-terminal methionine residues" |
| 2202 | YGR148C | RPL24B SGDID:S000003380, Chr VII from 787784-787317, reverse complement, Verified ORF, "Ribosomal protein L30 of the large (60S) ribosomal subunit, nearly identical to Rpl24Ap and has similarity to rat L24 ribosomal protein; not essential for translation but may be required for normal translation rate" |
| 2203 | YGR149W | YGR149W SGDID:S000003381, Chr VII from 789036-790334, Uncharacterized ORF, "Putative protein of unknown function; predicted to be an integal membrane protein" |
| 2204 | YGR150C | YGR150C SGDID:S000003382, Chr VII from 793058-790464, reverse complement, Verified ORF, "Protein of unknown function, contains PPR motifs; mutant has growth defects on both non-fermentable carbon sources and rich medium; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2205 | YGR152C | RSR1 SGDID:S000003384, Chr VII from 795497-794679, reverse complement, Verified ORF, "GTP-binding protein of the ras superfamily required for bud site selection, morphological changes in response to mating pheromone, and efficient cell fusion; localized to the plasma membrane; significantly similar to mammalian Rap GTPases" |
| 2206 | YGR153W | YGR153W SGDID:S000003385, Chr VII from 796097-796750, Uncharacterized ORF, "Putative protein of unknown function" |
| 2207 | YGR154C | GTO1 SGDID:S000003386, Chr VII from 797873-796803, reverse complement, Verified ORF, "Omega-class glutathione transferase; induced under oxidative stress; putative peroxisomal localization" |
| 2208 | YGR155W | CYS4 SGDID:S000003387, Chr VII from 798548-800071, Verified ORF, "Cystathionine beta-synthase, catalyzes the synthesis of cystathionine from serine and homocysteine, the first committed step in cysteine biosynthesis" |
| 2209 | YGR156W | PTI1 SGDID:S000003388, Chr VII from 800551-801828, Verified ORF, "Pta1p Interacting protein" |
| 2210 | YGR157W | CHO2 SGDID:S000003389, Chr VII from 802445-805054, Verified ORF, "Phosphatidylethanolamine methyltransferase (PEMT), catalyzes the first step in the conversion of phosphatidylethanolamine to phosphatidylcholine during the methylation pathway of phosphatidylcholine biosynthesis" |
| 2211 | YGR158C | MTR3 SGDID:S000003390, Chr VII from 806026-805274, reverse complement, Verified ORF, "3'5' exoribonuclease, exosome subunit; nucleolar protein involved in export of mRNA and ribosomal subunits; homologous to the E. coli exonuclease RNase PH" |
| 2212 | YGR159C | NSR1 SGDID:S000003391, Chr VII from 807661-806417, reverse complement, Verified ORF, "Nucleolar protein that binds nuclear localization sequences, required for pre-rRNA processing and ribosome biogenesis" |
| 2213 | YGR161C | RTS3 SGDID:S000003393, Chr VII from 809425-808634, reverse complement, Uncharacterized ORF, "Putative component of the protein phosphatase type 2A complex" |
| 2214 | YGR161C-C | YGR161C-C SGDID:S000007367, Chr VII from 823020-821698, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 2215 | YGR161C-D | YGR161C-D SGDID:S000007368, Chr VII from 823020-821716,821714-817752, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 2216 | YGR161W-A | YGR161W-A SGDID:S000007369, Chr VII from 811743-813059, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 2217 | YGR161W-B | YGR161W-B SGDID:S000007370, Chr VII from 811743-813035,813037-817056, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 2218 | YGR161W-C | YGR161W-C SGDID:S000029726, Chr VII from 810232-810510, Uncharacterized ORF, "Putative protein of unknown function; identified by sequence comparison with hemiascomycetous yeast species" |
| 2219 | YGR162W | TIF4631 SGDID:S000003394, Chr VII from 824064-826922, Verified ORF, "Translation initiation factor eIF4G, subunit of the mRNA cap-binding protein complex (eIF4F) that also contains eIF4E (Cdc33p); associates with the poly(A)-binding protein Pab1p, also interacts with eIF4A (Tif1p); homologous to Tif4632p" |
| 2220 | YGR163W | GTR2 SGDID:S000003395, Chr VII from 827557-828582, Verified ORF, "Putative GTP binding protein that negatively regulates Ran/Tc4 GTPase cycle; activates transcription; subunit of EGO and GSE complexes; required for sorting of Gap1p; localizes to cytoplasm and to chromatin; homolog of human RagC and RagD" |
| 2221 | YGR165W | MRPS35 SGDID:S000003397, Chr VII from 829121-830158, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 2222 | YGR166W | KRE11 SGDID:S000003398, Chr VII from 830520-832202, Verified ORF, "Protein involved in biosynthesis of cell wall beta-glucans; subunit of the TRAPP (transport protein particle) complex, which is involved in the late steps of endoplasmic reticulum to Golgi transport" |
| 2223 | YGR167W | CLC1 SGDID:S000003399, Chr VII from 832461-833162, Verified ORF, "Clathrin light chain, subunit of the major coat protein involved in intracellular protein transport and endocytosis; thought to regulate clathrin function; two Clathrin heavy chains (CHC1) form the clathrin triskelion structural component" |
| 2224 | YGR168C | YGR168C SGDID:S000003400, Chr VII from 834487-833357, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YGR168C is not an essential gene" |
| 2225 | YGR169C | PUS6 SGDID:S000003401, Chr VII from 835908-834694, reverse complement, Verified ORF, "Pseudouridine synthase responsible for modification of cytoplasmic and mitochondrial tRNAs at position 31; mutation of Asp168 to Ala abolishes enzyme activity; not essential for viability" |
| 2226 | YGR169C-A | YGR169C-A SGDID:S000028521, Chr VII from 836670-836392, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 2227 | YGR170W | PSD2 SGDID:S000003402, Chr VII from 837147-840563, Verified ORF, "Phosphatidylserine decarboxylase of the Golgi and vacuolar membranes, converts phosphatidylserine to phosphatidylethanolamine" |
| 2228 | YGR171C | MSM1 SGDID:S000003403, Chr VII from 842556-840829, reverse complement, Verified ORF, "Mitochondrial methionyl-tRNA synthetase (MetRS), functions as a monomer in mitochondrial protein synthesis; functions similarly to cytoplasmic MetRS although the cytoplasmic form contains a zinc-binding domain not found in Msm1p" |
| 2229 | YGR172C | YIP1 SGDID:S000003404, Chr VII from 843596-842850, reverse complement, Verified ORF, "Integral membrane protein required for the biogenesis of ER-derived COPII transport vesicles; interacts with Yif1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles" |
| 2230 | YGR173W | RBG2 SGDID:S000003405, Chr VII from 843859-844965, Uncharacterized ORF, "Protein with similarity to mammalian developmentally regulated GTP-binding protein" |
| 2231 | YGR174C | CBP4 SGDID:S000003406, Chr VII from 846410-845898, reverse complement, Verified ORF, "Mitochondrial protein required for assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex); interacts with Cbp3p and function is partially redundant with that of Cbp3p" |
| 2232 | YGR174W-A | YGR174W-A SGDID:S000028639, Chr VII from 846660-846746, Uncharacterized ORF, "Putative protein of unknown function" |
| 2233 | YGR175C | ERG1 SGDID:S000003407, Chr VII from 848428-846938, reverse complement, Verified ORF, "Squalene epoxidase, catalyzes the epoxidation of squalene to 2,3-oxidosqualene; plays an essential role in the ergosterol-biosynthesis pathway and is the specific target of the antifungal drug terbinafine" |
| 2234 | YGR177C | ATF2 SGDID:S000003409, Chr VII from 850441-848834, reverse complement, Verified ORF, "Alcohol acetyltransferase, may play a role in steroid detoxification; forms volatile esters during fermentation, which is important in brewing" |
| 2235 | YGR178C | PBP1 SGDID:S000003410, Chr VII from 853220-851052, reverse complement, Verified ORF, "Protein interacting with poly(A)-binding protein Pab1p; likely involved in controlling the extent of mRNA polyadenylation; forms a complex with Mkt1p that may regulate HO translation; interacts with Lsm12p in a copurification assay" |
| 2236 | YGR179C | OKP1 SGDID:S000003411, Chr VII from 854900-853680, reverse complement, Verified ORF, "Outer kinetochore protein, required for accurate mitotic chromosome segregation; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as a platform for kinetochore assembly" |
| 2237 | YGR180C | RNR4 SGDID:S000003412, Chr VII from 856306-855269, reverse complement, Verified ORF, "Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits" |
| 2238 | YGR181W | TIM13 SGDID:S000003413, Chr VII from 858292-858609, Verified ORF, "Mitochondrial intermembrane space protein, forms a complex with TIm8p that mediates import and insertion of a subset of polytopic inner membrane proteins; may prevent aggregation of incoming proteins in a chaperone-like manner" |
| 2239 | YGR183C | QCR9 SGDID:S000003415, Chr VII from 859481-859479,859265-859068, reverse complement, Verified ORF, "Subunit 9 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; required for electron transfer at the ubiquinol oxidase site of the complex" |
| 2240 | YGR184C | UBR1 SGDID:S000003416, Chr VII from 865758-859906, reverse complement, Verified ORF, "Ubiquitin-protein ligase (E3) that interacts with Rad6p/Ubc2p to ubiquitinate substrates of the N-end rule pathway; binds to the Rpn2p, Rpt1p, and Rpt6p proteins of the 19S particle of the 26S proteasome" |
| 2241 | YGR185C | TYS1 SGDID:S000003417, Chr VII from 867525-866341, reverse complement, Verified ORF, "Cytoplasmic tyrosyl-tRNA synthetase, class I aminoacyl-tRNA synthetase that aminoacylates tRNA(Tyr), required for cytoplasmic protein synthesis, interacts with positions 34 and 35 of the anticodon of tRNATyr" |
| 2242 | YGR186W | TFG1 SGDID:S000003418, Chr VII from 867779-869986, Verified ORF, "TFIIF (Transcription Factor II) largest subunit; involved in both transcription initiation and elongation of RNA polymerase II; homologous to human RAP74" |
| 2243 | YGR187C | HGH1 SGDID:S000003419, Chr VII from 871421-870237, reverse complement, Verified ORF, "Nonessential protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; similar to mammalian BRP16 (Brain protein 16)" |
| 2244 | YGR188C | BUB1 SGDID:S000003420, Chr VII from 875114-872049, reverse complement, Verified ORF, "Protein kinase that forms a complex with Mad1p and Bub3p that is crucial in the checkpoint mechanism required to prevent cell cycle progression into anaphase in the presence of spindle damage, associates with centromere DNA via Skp1p" |
| 2245 | YGR189C | CRH1 SGDID:S000003421, Chr VII from 878197-876674, reverse complement, Verified ORF, "Putative chitin transglycosidase, cell wall protein that functions in the transfer of chitin to beta(1-6)glucan; localizes to sites of polarized growth; expression is induced under cell wall stress conditions" |
| 2246 | YGR191W | HIP1 SGDID:S000003423, Chr VII from 880425-882236, Verified ORF, "High-affinity histidine permease, also involved in the transport of manganese ions" |
| 2247 | YGR192C | TDH3 SGDID:S000003424, Chr VII from 883815-882817, reverse complement, Verified ORF, "Glyceraldehyde-3-phosphate dehydrogenase, isozyme 3, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall" |
| 2248 | YGR193C | PDX1 SGDID:S000003425, Chr VII from 885746-884514, reverse complement, Verified ORF, "Dihydrolipoamide dehydrogenase (E3)-binding protein (E3BP) of the mitochondrial pyruvate dehydrogenase (PDH) complex, plays a structural role in the complex by binding and positioning E3 to the dihydrolipoamide acetyltransferase (E2) core" |
| 2249 | YGR194C | XKS1 SGDID:S000003426, Chr VII from 887880-886078, reverse complement, Verified ORF, "Xylulokinase, converts D-xylulose and ATP to xylulose 5-phosphate and ADP; rate limiting step in fermentation of xylulose; required for xylose fermentation by recombinant S. cerevisiae strains" |
| 2250 | YGR195W | SKI6 SGDID:S000003427, Chr VII from 888887-889627, Verified ORF, "3'-to-5' phosphorolytic exoribonuclease that is a subunit of the exosome; required for 3' processing of the 5.8S rRNA; involved in 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs" |
| 2251 | YGR196C | FYV8 SGDID:S000003428, Chr VII from 892191-889738, reverse complement, Verified ORF, "Protein of unknown function, required for survival upon exposure to K1 killer toxin" |
| 2252 | YGR197C | SNG1 SGDID:S000003429, Chr VII from 894145-892502, reverse complement, Verified ORF, "Protein involved in nitrosoguanidine (MNNG) resistance; expression is regulated by transcription factors involved in multidrug resistance" |
| 2253 | YGR198W | YPP1 SGDID:S000003430, Chr VII from 894698-897151, Verified ORF, "Cargo-transport protein involved in endocytosis; may interact with ribosomes, based on co-purification experiments; GFP-fusion protein localizes to the cytoplasm; YGR198W is an essential gene" |
| 2254 | YGR199W | PMT6 SGDID:S000003431, Chr VII from 897507-899786, Verified ORF, "Protein O-mannosyltransferase, transfers mannose from dolichyl phosphate-D-mannose to protein serine/threonine residues of secretory proteins; reaction is essential for cell wall rigidity; member of a family of mannosyltransferases" |
| 2255 | YGR200C | ELP2 SGDID:S000003432, Chr VII from 902275-899909, reverse complement, Verified ORF, "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; target of Kluyveromyces lactis zymocin" |
| 2256 | YGR201C | YGR201C SGDID:S000003433, Chr VII from 903202-902525, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 2257 | YGR202C | PCT1 SGDID:S000003434, Chr VII from 904753-903479, reverse complement, Verified ORF, "Cholinephosphate cytidylyltransferase, also known as CTP:phosphocholine cytidylyltransferase, rate-determining enzyme of the CDP-choline pathway for phosphatidylcholine synthesis, inhibited by Sec14p, activated upon lipid-binding" |
| 2258 | YGR203W | YGR203W SGDID:S000003435, Chr VII from 905242-905688, Uncharacterized ORF, "Putative protein with sequence similarity to protein tyrosine phosphatases of the CDC25-like phosphatase family; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus" |
| 2259 | YGR204C-A | YGR204C-A SGDID:S000028640, Chr VII from 909179-909066, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 2260 | YGR204W | ADE3 SGDID:S000003436, Chr VII from 905939-908779, Verified ORF, "Cytoplasmic trifunctional enzyme C1-tetrahydrofolate synthase, involved in single carbon metabolism and required for biosynthesis of purines, thymidylate, methionine, and histidine" |
| 2261 | YGR205W | YGR205W SGDID:S000003437, Chr VII from 909218-910090, Verified ORF, "ATP-binding protein of unknown function; crystal structure resembles that of E.coli pantothenate kinase and other small kinases" |
| 2262 | YGR206W | MVB12 SGDID:S000003438, Chr VII from 910437-910742, Verified ORF, "ESCRT-I subunit required to stabilize oligomers of the ESCRT-I core complex (Stp22p, Vps28p, Srn2p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; deletion mutant is sensitive to rapamycin and nystatin" |
| 2263 | YGR207C | YGR207C SGDID:S000003439, Chr VII from 911633-910848, reverse complement, Verified ORF, "Protein that interacts with frataxin (Yfh1p); putative homolog of mammalian electron transfer flavoprotein complex subunit ETF-beta; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2264 | YGR208W | SER2 SGDID:S000003440, Chr VII from 911888-912817, Verified ORF, "Phosphoserine phosphatase of the phosphoglycerate pathway, involved in serine and glycine biosynthesis, expression is regulated by the available nitrogen source" |
| 2265 | YGR209C | TRX2 SGDID:S000003441, Chr VII from 913232-912918, reverse complement, Verified ORF, "Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance" |
| 2266 | YGR210C | YGR210C SGDID:S000003442, Chr VII from 914743-913508, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 2267 | YGR211W | ZPR1 SGDID:S000003443, Chr VII from 915246-916706, Verified ORF, "Essential protein with two zinc fingers, present in the nucleus of growing cells but relocates to the cytoplasm in starved cells via a process mediated by Cpr1p; binds to translation elongation factor eEF-1 (Tef1p)" |
| 2268 | YGR212W | SLI1 SGDID:S000003444, Chr VII from 917045-918451, Verified ORF, "N-acetyltransferase, confers resistance to the sphingolipid biosynthesis inhibitor myriocin (ISP-1) by converting it into N-acetyl-myriocin, co-operates with Ypk1p in mediating resistance to myriocin" |
| 2269 | YGR213C | RTA1 SGDID:S000003445, Chr VII from 919470-918517, reverse complement, Verified ORF, "Protein involved in 7-aminocholesterol resistance; has seven potential membrane-spanning regions; expression is induced under both low-heme and low-oxygen conditions" |
| 2270 | YGR214W | RPS0A SGDID:S000003446, Chr VII from 920580-920669,921125-921793, Verified ORF, "Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Bp; required for maturation of 18S rRNA along with Rps0Bp; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal" |
| 2271 | YGR215W | RSM27 SGDID:S000003447, Chr VII from 922180-922512, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 2272 | YGR216C | GPI1 SGDID:S000003448, Chr VII from 924467-922638, reverse complement, Verified ORF, "Membrane protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; human and mouse GPI1p are functional homologs" |
| 2273 | YGR217W | CCH1 SGDID:S000003449, Chr VII from 924699-930818, Verified ORF, "Voltage-gated high-affinity calcium channel involved in calcium influx in response to some environmental stresses as well as exposure to mating pheromones; interacts and co-localizes with Mid1p, suggesting Cch1p and Mid1p function together" |
| 2274 | YGR218W | CRM1 SGDID:S000003450, Chr VII from 932544-935798, Verified ORF, "Major karyopherin, involved in export of proteins, RNAs, and ribosomal subunits from the nucleus" |
| 2275 | YGR220C | MRPL9 SGDID:S000003452, Chr VII from 936886-936077, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 2276 | YGR221C | TOS2 SGDID:S000003453, Chr VII from 938995-937127, reverse complement, Verified ORF, "Protein involved in localization of Cdc24p to the site of bud growth; may act as a membrane anchor; localizes to the bud neck and bud tip; potentially phosphorylated by Cdc28p" |
| 2277 | YGR222W | PET54 SGDID:S000003454, Chr VII from 939926-940807, Verified ORF, "Mitochondrial inner membrane protein that binds to the 5' UTR of the COX3 mRNA to activate its translation together with Pet122p and Pet494p; also binds to the COX1 Group I intron AI5 beta to facilitate exon ligation during splicing" |
| 2278 | YGR223C | HSV2 SGDID:S000003455, Chr VII from 942218-940872, reverse complement, Verified ORF, "Phosphatidylinositol 3,5-bisphosphate-binding protein, predicted to fold as a seven-bladed beta-propeller; displays punctate cytoplasmic localization" |
| 2279 | YGR224W | AZR1 SGDID:S000003456, Chr VII from 942809-944650, Verified ORF, "Plasma membrane transporter of the major facilitator superfamily, involved in resistance to azole drugs such as ketoconazole and fluconazole" |
| 2280 | YGR225W | AMA1 SGDID:S000003457, Chr VII from 945148-946330,946424-947022, Verified ORF, "Activator of meiotic anaphase promoting complex (APC/C); Cdc20p family member; required for initiation of spore wall assembly; required for Clb1p degradation during meiosis" |
| 2281 | YGR227W | DIE2 SGDID:S000003459, Chr VII from 947423-949000, Verified ORF, "Dolichyl-phosphoglucose-dependent alpha-1,2 glucosyltransferase of the ER, functions in the pathway that synthesizes the dolichol-linked oligosaccharide precursor for N-linked protein glycosylation, has a role in regulation of ITR1 and INO1" |
| 2282 | YGR229C | SMI1 SGDID:S000003461, Chr VII from 950902-949385, reverse complement, Verified ORF, "Protein involved in the regulation of cell wall synthesis; proposed to be involved in coordinating cell cycle progression with cell wall integrity" |
| 2283 | YGR230W | BNS1 SGDID:S000003462, Chr VII from 951897-952310, Verified ORF, "Protein with some similarity to Spo12p; overexpression bypasses need for Spo12p, but not required for meiosis" |
| 2284 | YGR231C | PHB2 SGDID:S000003463, Chr VII from 953483-952551, reverse complement, Verified ORF, "Subunit of the prohibitin complex (Phb1p-Phb2p), a 1.2 MDa ring-shaped inner mitochondrial membrane chaperone that stabilizes newly synthesized proteins; determinant of replicative life span; involved in mitochondrial segregation" |
| 2285 | YGR232W | NAS6 SGDID:S000003464, Chr VII from 953963-954649, Verified ORF, "Regulatory, non-ATPase subunit of the 26S proteasome; homolog of the human oncoprotein gankyrin, which interacts with the retinoblastoma tumor suppressor (Rb) and cyclin-dependent kinase 4/6" |
| 2286 | YGR233C | PHO81 SGDID:S000003465, Chr VII from 958213-954677, reverse complement, Verified ORF, "Cyclin-dependent kinase (CDK) inhibitor, regulates Pho80p-Pho85p and Pcl7p-Pho85p cyclin-CDK complexes in response to phosphate levels; inhibitory activity for Pho80p-Pho85p requires myo-D-inositol heptakisphosphate (IP7) generated by Vip1p" |
| 2287 | YGR234W | YHB1 SGDID:S000003466, Chr VII from 959908-961107, Verified ORF, "Nitric oxide oxidoreductase, flavohemoglobin involved in nitric oxide detoxification; plays a role in the oxidative and nitrosative stress responses" |
| 2288 | YGR235C | YGR235C SGDID:S000003467, Chr VII from 962065-961364, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2289 | YGR236C | SPG1 SGDID:S000003468, Chr VII from 962821-962534, reverse complement, Verified ORF, "Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2290 | YGR237C | YGR237C SGDID:S000003469, Chr VII from 965660-963303, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 2291 | YGR238C | KEL2 SGDID:S000003470, Chr VII from 968692-966044, reverse complement, Verified ORF, "Protein that functions in a complex with Kel1p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate" |
| 2292 | YGR239C | PEX21 SGDID:S000003471, Chr VII from 970058-969192, reverse complement, Verified ORF, "Peroxin required for targeting of peroxisomal matrix proteins containing PTS2; interacts with Pex7p; partially redundant with Pex18p" |
| 2293 | YGR240C | PFK1 SGDID:S000003472, Chr VII from 973739-970776, reverse complement, Verified ORF, "Alpha subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes" |
| 2294 | YGR240C-A | YGR240C-A SGDID:S000028551, Chr VII from 974782-974582, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 2295 | YGR241C | YAP1802 SGDID:S000003473, Chr VII from 976586-974880, reverse complement, Verified ORF, "Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1801p, member of the AP180 protein family" |
| 2296 | YGR243W | YGR243W SGDID:S000003475, Chr VII from 977341-977781, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2297 | YGR244C | LSC2 SGDID:S000003476, Chr VII from 979324-978041, reverse complement, Verified ORF, "Beta subunit of succinyl-CoA ligase, which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate" |
| 2298 | YGR245C | SDA1 SGDID:S000003477, Chr VII from 982073-979770, reverse complement, Verified ORF, "Highly conserved nuclear protein required for actin cytoskeleton organization and passage through Start, plays a critical role in G1 events, binds Nap1p, also involved in 60S ribosome biogenesis" |
| 2299 | YGR246C | BRF1 SGDID:S000003478, Chr VII from 984277-982487, reverse complement, Verified ORF, "TFIIIB B-related factor, one of three subunits of RNA polymerase III transcription initiation factor TFIIIB, binds TFIIIC and TBP and recruits RNA pol III to promoters, amino-terminal half is homologous to TFIIB" |
| 2300 | YGR247W | CPD1 SGDID:S000003479, Chr VII from 984971-985690, Verified ORF, "Cyclic nucleotide phosphodiesterase, hydrolyzes ADP-ribose 1'', 2''-cyclic phosphate to ADP-ribose 1''-phosphate; may have a role in tRNA splicing; no detectable phenotype is conferred by null mutation or by overexpression" |
| 2301 | YGR248W | SOL4 SGDID:S000003480, Chr VII from 985977-986744, Verified ORF, "6-phosphogluconolactonase with similarity to Sol3p" |
| 2302 | YGR249W | MGA1 SGDID:S000003481, Chr VII from 988054-989424, Verified ORF, "Protein similar to heat shock transcription factor; multicopy suppressor of pseudohyphal growth defects of ammonium permease mutants" |
| 2303 | YGR250C | YGR250C SGDID:S000003482, Chr VII from 993526-991181, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 2304 | YGR251W | YGR251W SGDID:S000003483, Chr VII from 995644-996234, Uncharacterized ORF, "Putative protein of unknown function; deletion mutant has defects in pre-rRNA processing; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the nucleolus; YGR251W is an essential gene" |
| 2305 | YGR252W | GCN5 SGDID:S000003484, Chr VII from 996874-998193, Verified ORF, "Histone acetyltransferase, acetylates N-terminal lysines on histones H2B and H3; catalytic subunit of the ADA and SAGA histone acetyltransferase complexes; founding member of the Gcn5p-related N-acetyltransferase superfamily" |
| 2306 | YGR253C | PUP2 SGDID:S000003485, Chr VII from 999145-998363, reverse complement, Verified ORF, "Alpha 5 subunit of the 20S proteasome involved in ubiquitin-dependent catabolism; human homolog is subunit zeta" |
| 2307 | YGR254W | ENO1 SGDID:S000003486, Chr VII from 1000932-1002245, Verified ORF, "Enolase I, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is repressed in response to glucose" |
| 2308 | YGR255C | COQ6 SGDID:S000003487, Chr VII from 1003967-1002528, reverse complement, Verified ORF, "Putative flavin-dependent monooxygenase, involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes" |
| 2309 | YGR256W | GND2 SGDID:S000003488, Chr VII from 1004630-1006108, Verified ORF, "6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone" |
| 2310 | YGR257C | MTM1 SGDID:S000003489, Chr VII from 1007311-1006211, reverse complement, Verified ORF, "Mitochondrial protein of the mitochondrial carrier family, involved in activating mitochondrial Sod2p probably by facilitating insertion of an essential manganese cofactor" |
| 2311 | YGR258C | RAD2 SGDID:S000003490, Chr VII from 1010772-1007677, reverse complement, Verified ORF, "Single-stranded DNA endonuclease, cleaves single-stranded DNA during nucleotide excision repair to excise damaged DNA; subunit of Nucleotide Excision Repair Factor 3 (NEF3); homolog of human XPG protein" |
| 2312 | YGR260W | TNA1 SGDID:S000003492, Chr VII from 1012491-1014095, Verified ORF, "High affinity nicotinic acid plasma membrane permease, responsible for uptake of low levels of nicotinic acid; expression of the gene increases in the absence of extracellular nicotinic acid or para-aminobenzoate (PABA)" |
| 2313 | YGR261C | APL6 SGDID:S000003493, Chr VII from 1016756-1014327, reverse complement, Verified ORF, "Beta3-like subunit of the yeast AP-3 complex; functions in transport of alkaline phosphatase to the vacuole via the alternate pathway; exists in both cytosolic and peripherally associated membrane-bound pools" |
| 2314 | YGR262C | BUD32 SGDID:S000003494, Chr VII from 1017765-1016980, reverse complement, Verified ORF, "Protein kinase proposed to be involved in bud-site selection, telomere uncapping and elongation, and transcription; component of the EKC/KEOPS protein complex with Kae1p, Cgi121p, Pcc1p, and Gon7p" |
| 2315 | YGR263C | SAY1 SGDID:S000003495, Chr VII from 1019247-1017973, reverse complement, Verified ORF, "Sterol deacetylase; component of the sterol acetylation/deacetylation cycle along with Atf2p; integral membrane protein with active site in the ER lumen; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum" |
| 2316 | YGR264C | MES1 SGDID:S000003496, Chr VII from 1021859-1019604, reverse complement, Verified ORF, "Methionyl-tRNA synthetase, forms a complex with glutamyl-tRNA synthetase (Gus1p) and Arc1p, which increases the catalytic efficiency of both tRNA synthetases; also has a role in nuclear export of tRNAs" |
| 2317 | YGR266W | YGR266W SGDID:S000003498, Chr VII from 1022662-1024767, Verified ORF, "Protein of unknown function, predicted to contain a single transmembrane domain; localized to both the mitochondrial outer membrane and the plasma membrane" |
| 2318 | YGR267C | FOL2 SGDID:S000003499, Chr VII from 1025741-1025010, reverse complement, Verified ORF, "GTP-cyclohydrolase I, catalyzes the first step in the folic acid biosynthetic pathway" |
| 2319 | YGR268C | HUA1 SGDID:S000003500, Chr VII from 1026659-1026063, reverse complement, Verified ORF, "Cytoplasmic protein containing a zinc finger domain with sequence similarity to that of Type I J-proteins; computational analysis of large-scale protein-protein interaction data suggests a possible role in actin patch assembly" |
| 2320 | YGR270W | YTA7 SGDID:S000003502, Chr VII from 1027376-1031515, Verified ORF, "Protein that localizes to chromatin and has a role in regulation of histone gene expression; has a bromodomain-like region that interacts with the N-terminal tail of histone H3, and an ATPase domain; potentially phosphorylated by Cdc28p" |
| 2321 | YGR271C-A | EFG1 SGDID:S000007608, Chr VII from 1038507-1037806, reverse complement, Verified ORF, "Protein of unknown function; null mutant is sensitive to hydroxyurea and is delayed in recovering from alpha-factor arrest; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus" |
| 2322 | YGR271W | SLH1 SGDID:S000003503, Chr VII from 1031797-1037700, Verified ORF, "Putative RNA helicase related to Ski2p, involved in translation inhibition of non-poly(A) mRNAs; required for repressing propagation of dsRNA viruses" |
| 2323 | YGR273C | YGR273C SGDID:S000003505, Chr VII from 1039245-1038721, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; deletion mutant has no readily detectable phenotype; expression downregulated by treatment with 8-methoxypsoralen plus UVA irradiation" |
| 2324 | YGR274C | TAF1 SGDID:S000003506, Chr VII from 1043102-1039902, reverse complement, Verified ORF, "TFIID subunit (145 kDa), involved in RNA polymerase II transcription initiation, has histone acetyltransferase activity, involved in promoter binding and G1/S progression" |
| 2325 | YGR275W | RTT102 SGDID:S000003507, Chr VII from 1043283-1043756, Verified ORF, "Component of both the SWI/SNF and RSC chromatin remodeling complexes, suggested role in chromosome maintenance; possible weak regulator of Ty1 transposition" |
| 2326 | YGR276C | RNH70 SGDID:S000003508, Chr VII from 1045487-1043826, reverse complement, Verified ORF, "3' exoribonuclease, required for 5S rRNA and tRNA-Arg3 maturation" |
| 2327 | YGR277C | YGR277C SGDID:S000003509, Chr VII from 1046568-1045651, reverse complement, Uncharacterized ORF, "Putative pantetheine-phosphate adenylyltransferase (PPAT) that catalyzes the fourth step in the biosynthesis of coenzyme A from pantothenate; conserved in bacteria, humans, and plants; essential for viability" |
| 2328 | YGR278W | CWC22 SGDID:S000003510, Chr VII from 1046738-1048471, Verified ORF, "Essential protein, component of a complex containing Cef1p, has similarity to S. pombe Cwf22p; putative spliceosomal component, based on computational analysis of large-scale protein-protein interaction data" |
| 2329 | YGR279C | SCW4 SGDID:S000003511, Chr VII from 1049965-1048805, reverse complement, Verified ORF, "Cell wall protein with similarity to glucanases; scw4 scw10 double mutants exhibit defects in mating" |
| 2330 | YGR280C | PXR1 SGDID:S000003512, Chr VII from 1051732-1050917, reverse complement, Verified ORF, "Essential protein involved in rRNA and snoRNA maturation; competes with TLC1 RNA for binding to Est2p, suggesting a role in negative regulation of telomerase; human homolog inhibits telomerase; contains a G-patch RNA interacting domain" |
| 2331 | YGR281W | YOR1 SGDID:S000003513, Chr VII from 1052831-1057264, Verified ORF, "Plasma membrane ATP-binding cassette (ABC) transporter, multidrug transporter mediates export of many different organic anions including oligomycin" |
| 2332 | YGR282C | BGL2 SGDID:S000003514, Chr VII from 1058731-1057790, reverse complement, Verified ORF, "Endo-beta-1,3-glucanase, major protein of the cell wall, involved in cell wall maintenance" |
| 2333 | YGR283C | YGR283C SGDID:S000003515, Chr VII from 1060047-1059022, reverse complement, Verified ORF, "Protein of unknown function; may interact with ribosomes, based on co-purification experiments; deletion mutant is resistant to fluconazole; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus" |
| 2334 | YGR284C | ERV29 SGDID:S000003516, Chr VII from 1061597-1060665, reverse complement, Verified ORF, "Protein localized to COPII-coated vesicles, involved in vesicle formation and incorporation of specific secretory cargo" |
| 2335 | YGR285C | ZUO1 SGDID:S000003517, Chr VII from 1063160-1061859, reverse complement, Verified ORF, "Cytosolic ribosome-associated chaperone that acts, together with Ssz1p and the Ssb proteins, as a chaperone for nascent polypeptide chains; contains a DnaJ domain and functions as a J-protein partner for Ssb1p and Ssb2p" |
| 2336 | YGR286C | BIO2 SGDID:S000003518, Chr VII from 1064947-1063820, reverse complement, Verified ORF, "Biotin synthase, catalyzes the conversion of dethiobiotin to biotin, which is the last step of the biotin biosynthesis pathway; complements E. coli bioB mutant" |
| 2337 | YGR287C | YGR287C SGDID:S000003519, Chr VII from 1068998-1067229, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; has similarity to alpha-D-glucosidase (maltase); authentic, non-tagged protein detected in purified mitochondria in high-throughput studies" |
| 2338 | YGR288W | MAL13 SGDID:S000003520, Chr VII from 1070300-1071721, Verified ORF, "MAL-activator protein, part of complex locus MAL1; nonfunctional in genomic reference strain S288C" |
| 2339 | YGR289C | MAL11 SGDID:S000003521, Chr VII from 1075820-1073970, reverse complement, Verified ORF, "Inducible high-affinity maltose transporter (alpha-glucoside transporter); encoded in the MAL1 complex locus; member of the 12 transmembrane domain superfamily of sugar transporters; broad substrate specificity that includes maltotriose" |
| 2340 | YGR292W | MAL12 SGDID:S000003524, Chr VII from 1076606-1078360, Verified ORF, "Maltase (alpha-D-glucosidase), inducible protein involved in maltose catabolism; encoded in the MAL1 complex locus" |
| 2341 | YGR294W | YGR294W SGDID:S000003526, Chr VII from 1080313-1080675, Uncharacterized ORF, "Hypothetical protein" |
| 2342 | YGR295C | COS6 SGDID:S000003527, Chr VII from 1082736-1081591, reverse complement, Verified ORF, "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" |
| 2343 | YGR296W | YRF1-3 SGDID:S000003528, Chr VII from 1084871-1084889,1085038-1090598, Verified ORF, "Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p" |
| 2344 | YHL001W | RPL14B SGDID:S000000993, Chr VIII from 104272-104400,104799-105086, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl14Ap and has similarity to rat L14 ribosomal protein" |
| 2345 | YHL002W | HSE1 SGDID:S000000994, Chr VIII from 102607-103965, Verified ORF, "Subunit of the endosomal Vps27p-Hse1p complex required for sorting of ubiquitinated membrane proteins into intralumenal vesicles prior to vacuolar degradation, as well as for recycling of Golgi proteins and formation of lumenal membranes" |
| 2346 | YHL003C | LAG1 SGDID:S000000995, Chr VIII from 101879-100644, reverse complement, Verified ORF, "Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lac1p" |
| 2347 | YHL004W | MRP4 SGDID:S000000996, Chr VIII from 99215-100399, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 2348 | YHL006C | SHU1 SGDID:S000000998, Chr VIII from 98791-98339, reverse complement, Verified ORF, "Protein of unassigned function involved in mutation suppression, important for error-free repair of spontaneous and induced DNA lesions to protect the genome from mutation; associates with Shu2p, Psy3p, and Csm2p" |
| 2349 | YHL007C | STE20 SGDID:S000000999, Chr VIII from 97933-95114, reverse complement, Verified ORF, "Signal transducing kinase of the PAK (p21-activated kinase) family, involved in pheromone response and pseudohyphal/invasive growth pathways, activated by Cdc42p; binds Ste4p at a GBB motif present in noncatalytic domains of PAK kinases" |
| 2350 | YHL008C | YHL008C SGDID:S000001000, Chr VIII from 94506-92623, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, does not appear to be involved in monocarboxylic acid transport; green fluorescent protein (GFP)-fusion protein localizes to the vacuole" |
| 2351 | YHL009C | YAP3 SGDID:S000001001, Chr VIII from 85056-84064, reverse complement, Verified ORF, "Basic leucine zipper (bZIP) transcription factor" |
| 2352 | YHL009W-A | YHL009W-A SGDID:S000007371, Chr VIII from 85905-87146, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 2353 | YHL009W-B | YHL009W-B SGDID:S000007372, Chr VIII from 85905-86990,86992-91314, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 2354 | YHL010C | YHL010C SGDID:S000001002, Chr VIII from 83717-81960, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, contains a zinc finger region and has homology to human BRAP2, which is a cytoplasmic protein that binds nuclear localization sequences" |
| 2355 | YHL011C | PRS3 SGDID:S000001003, Chr VIII from 81612-80650, reverse complement, Verified ORF, "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes" |
| 2356 | YHL012W | YHL012W SGDID:S000001004, Chr VIII from 78932-80413, Uncharacterized ORF, "Putative protein of unknown function, has some homology to Ugp1p, which encodes UDP-glucose pyrophosphorylase" |
| 2357 | YHL013C | OTU2 SGDID:S000001005, Chr VIII from 78350-77427, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; member of the ovarian tumor-like (OTU) superfamily of predicted cysteine proteases; shows cytoplasmic localization" |
| 2358 | YHL014C | YLF2 SGDID:S000001006, Chr VIII from 77311-76094, reverse complement, Verified ORF, "Protein of unknown function, has weak similarity to E. coli GTP-binding protein gtp1; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2359 | YHL015W | RPS20 SGDID:S000001007, Chr VIII from 75409-75774, Verified ORF, "Protein component of the small (40S) ribosomal subunit; overproduction suppresses mutations affecting RNA polymerase III-dependent transcription; has similarity to E. coli S10 and rat S20 ribosomal proteins" |
| 2360 | YHL015W-A | YHL015W-A SGDID:S000028828, Chr VIII from 74696-74779, Uncharacterized ORF, "Putative protein of unknown function" |
| 2361 | YHL016C | DUR3 SGDID:S000001008, Chr VIII from 74241-72034, reverse complement, Verified ORF, "Plasma membrane transporter for both urea and polyamines, expression is highly sensitive to nitrogen catabolite repression and induced by allophanate, the last intermediate of the allantoin degradative pathway" |
| 2362 | YHL017W | YHL017W SGDID:S000001009, Chr VIII from 70273-71871, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein co-localizes with clathrin-coated vesicles" |
| 2363 | YHL018W | YHL018W SGDID:S000001010, Chr VIII from 69705-70067, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria and is induced in response to the DNA-damaging agent MMS" |
| 2364 | YHL019C | APM2 SGDID:S000001011, Chr VIII from 69545-67728, reverse complement, Verified ORF, "Protein of unknown function, homologous to the medium chain of mammalian clathrin-associated protein complex; involved in vesicular transport" |
| 2365 | YHL020C | OPI1 SGDID:S000001012, Chr VIII from 67453-66239, reverse complement, Verified ORF, "Transcriptional regulator of a variety of genes; phosphorylation by protein kinase A stimulates Opi1p function in negative regulation of phospholipid biosynthetic genes; involved in telomere maintenance" |
| 2366 | YHL021C | YHL021C SGDID:S000001013, Chr VIII from 65856-64459, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays decreased frequency of mitochondrial genome loss (petite formation)" |
| 2367 | YHL022C | SPO11 SGDID:S000001014, Chr VIII from 64155-62959, reverse complement, Verified ORF, "Meiosis-specific protein that initiates meiotic recombination by catalyzing the formation of double-strand breaks in DNA via a transesterification reaction; required for homologous chromosome pairing and synaptonemal complex formation" |
| 2368 | YHL023C | RMD11 SGDID:S000001015, Chr VIII from 62561-59121, reverse complement, Verified ORF, "Protein required for meiosis" |
| 2369 | YHL024W | RIM4 SGDID:S000001016, Chr VIII from 56647-58788, Verified ORF, "Putative RNA-binding protein required for the expression of early and middle sporulation genes" |
| 2370 | YHL025W | SNF6 SGDID:S000001017, Chr VIII from 54849-55847, Verified ORF, "Subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; functions interdependently in transcriptional activation with Snf2p and Snf5p" |
| 2371 | YHL026C | YHL026C SGDID:S000001018, Chr VIII from 54164-53217, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YHL026C is not an essential gene; in 2005 the start site was moved 141 nt upstream (see Locus History)" |
| 2372 | YHL027W | RIM101 SGDID:S000001019, Chr VIII from 51109-52986, Verified ORF, "Transcriptional repressor involved in response to pH and in cell wall construction; required for alkaline pH-stimulated haploid invasive growth and sporulation; activated by proteolytic processing; similar to A. nidulans PacC" |
| 2373 | YHL028W | WSC4 SGDID:S000001020, Chr VIII from 48761-50578, Verified ORF, "ER membrane protein involved in the translocation of soluble secretory proteins and insertion of membrane proteins into the ER membrane; may also have a role in the stress response but has only partial functional overlap with WSC1-3" |
| 2374 | YHL029C | YHL029C SGDID:S000001021, Chr VIII from 47966-45927, reverse complement, Uncharacterized ORF, "Cytoplasmic protein required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts" |
| 2375 | YHL030W | ECM29 SGDID:S000001022, Chr VIII from 40082-45688, Verified ORF, "Major component of the proteasome; tethers the proteasome core particle to the regulatory particle, and enhances the stability of the proteasome" |
| 2376 | YHL031C | GOS1 SGDID:S000001023, Chr VIII from 39484-38813, reverse complement, Verified ORF, "v-SNARE protein involved in Golgi transport, homolog of the mammalian protein GOS-28/GS28" |
| 2377 | YHL032C | GUT1 SGDID:S000001024, Chr VIII from 38506-36377, reverse complement, Verified ORF, "Glycerol kinase, converts glycerol to glycerol-3-phosphate; glucose repression of expression is mediated by Adr1p and Ino2p-Ino4p; derepression of expression on non-fermentable carbon sources is mediated by Opi1p and Rsf1p" |
| 2378 | YHL033C | RPL8A SGDID:S000001025, Chr VIII from 36023-35253, reverse complement, Verified ORF, "Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Bp and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits" |
| 2379 | YHL034C | SBP1 SGDID:S000001026, Chr VIII from 34075-33191, reverse complement, Verified ORF, "Putative RNA binding protein; involved in translational repression and found in cytoplasmic P bodies; found associated with small nucleolar RNAs snR10 and snR11" |
| 2380 | YHL035C | VMR1 SGDID:S000001027, Chr VIII from 32754-27976, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; member of the ATP-binding cassette (ABC) family; potential Cdc28p substrate; detected in purified mitochondria in high-throughput studies" |
| 2381 | YHL036W | MUP3 SGDID:S000001028, Chr VIII from 26239-27879, Verified ORF, "Low affinity methionine permease, similar to Mup1p" |
| 2382 | YHL038C | CBP2 SGDID:S000001030, Chr VIII from 25506-23614, reverse complement, Verified ORF, "Mitochondrial protein required for splicing of the group I intron aI5 of the COB pre-mRNA, binds to the RNA to promote splicing; also involved in but not essential for splicing of the COB bI2 intron and the intron in the 21S rRNA gene" |
| 2383 | YHL039W | YHL039W SGDID:S000001031, Chr VIII from 21780-23537, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 2384 | YHL040C | ARN1 SGDID:S000001032, Chr VIII from 20968-19085, reverse complement, Verified ORF, "Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; responsible for uptake of iron bound to ferrirubin, ferrirhodin, and related siderophores" |
| 2385 | YHL042W | YHL042W SGDID:S000001034, Chr VIII from 15665-16117, Uncharacterized ORF, "Putative protein of unknown function; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" |
| 2386 | YHL043W | ECM34 SGDID:S000001035, Chr VIII from 14899-15411, Verified ORF, "Putative protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" |
| 2387 | YHL044W | YHL044W SGDID:S000001036, Chr VIII from 13563-14270, Uncharacterized ORF, "Putative integral membrane protein, member of DUP240 gene family; green fluorescent protein (GFP)-fusion protein localizes to the plasma membrane in a punctate pattern" |
| 2388 | YHL046C | YHL046C SGDID:S000001038, Chr VIII from 12283-11921, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; not an essential gene" |
| 2389 | YHL047C | ARN2 SGDID:S000001039, Chr VIII from 10211-8298, reverse complement, Verified ORF, "Transporter, member of the ARN family of transporters that specifically recognize siderophore-iron chelates; responsible for uptake of iron bound to the siderophore triacetylfusarinine C" |
| 2390 | YHL048C-A | YHL048C-A SGDID:S000028829, Chr VIII from 5796-5662, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 2391 | YHL048W | COS8 SGDID:S000001040, Chr VIII from 6400-7545, Verified ORF, "Nuclear membrane protein, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins; regulation suggests a potential role in the unfolded protein response" |
| 2392 | YHL049C | YHL049C SGDID:S000001041, Chr VIII from 4540-3725, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 2393 | YHL050C | YHL050C SGDID:S000001042, Chr VIII from 3310-2670,1897-445, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, potential Cdc28p substrate" |
| 2394 | YHR001W | OSH7 SGDID:S000001043, Chr VIII from 106050-107363, Verified ORF, "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability" |
| 2395 | YHR001W-A | QCR10 SGDID:S000003529, Chr VIII from 107821-107826,107890-108117, Verified ORF, "Subunit of the ubiqunol-cytochrome c oxidoreductase complex which includes Cobp, Rip1p, Cyt1p, Cor1p, Qcr2p, Qcr6p, Qcr7p, Qcr8p, Qcr9p, and Qcr10p and comprises part of the mitochondrial respiratory chain" |
| 2396 | YHR002W | LEU5 SGDID:S000001044, Chr VIII from 108807-109880, Verified ORF, "Mitochondrial carrier protein involved in the accumulation of CoA in the mitochondrial matrix; homolog of human Graves disease protein; does not encode an isozyme of Leu4p, as first hypothesized" |
| 2397 | YHR003C | YHR003C SGDID:S000001045, Chr VIII from 111312-110023, reverse complement, Verified ORF, "Protein of unknown function, localized to the mitochondrial outer membrane" |
| 2398 | YHR004C | NEM1 SGDID:S000001046, Chr VIII from 113089-111749, reverse complement, Verified ORF, "Catalytic subunit of Nem1p-Spo7p phosphatase holoenzyme, which regulates nuclear growth by controlling recruitment of Pah1p onto promoters of phospholipid biosynthetic genes; required for normal nuclear envelope morphology and sporulation" |
| 2399 | YHR005C | GPA1 SGDID:S000001047, Chr VIII from 114912-113494, reverse complement, Verified ORF, "GTP-binding alpha subunit of the heterotrimeric G protein that couples to pheromone receptors; negatively regulates the mating pathway by sequestering G(beta)gamma and by triggering an adaptive response; activates Vps34p at the endosome" |
| 2400 | YHR005C-A | MRS11 SGDID:S000003530, Chr VIII from 115896-115615, reverse complement, Verified ORF, "Essential protein of the mitochondrial intermembrane space, forms a complex with Tim9p (TIM10 complex) that mediates insertion of hydrophobic proteins at the inner membrane, has homology to Mrs5p, which is also involved in this process" |
| 2401 | YHR006W | STP2 SGDID:S000001048, Chr VIII from 117809-119434, Verified ORF, "Transcription factor, activated by proteolytic processing in response to signals from the SPS sensor system for external amino acids; activates transcription of amino acid permease genes" |
| 2402 | YHR007C | ERG11 SGDID:S000001049, Chr VIII from 121678-120086, reverse complement, Verified ORF, "Lanosterol 14-alpha-demethylase, catalyzes the C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in the ergosterol biosynthesis pathway; member of the cytochrome P450 family" |
| 2403 | YHR007C-A | YHR007C-A SGDID:S000028830, Chr VIII from 122760-122545, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 2404 | YHR008C | SOD2 SGDID:S000001050, Chr VIII from 123585-122884, reverse complement, Verified ORF, "Mitochondrial superoxide dismutase, protects cells against oxygen toxicity; phosphorylated" |
| 2405 | YHR009C | YHR009C SGDID:S000001051, Chr VIII from 125675-124104, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; not an essential gene" |
| 2406 | YHR010W | RPL27A SGDID:S000001052, Chr VIII from 126515-126545,127107-127486, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl27Bp and has similarity to rat L27 ribosomal protein" |
| 2407 | YHR011W | DIA4 SGDID:S000001053, Chr VIII from 127774-129114, Verified ORF, "Probable mitochondrial seryl-tRNA synthetase, mutant displays increased invasive and pseudohyphal growth" |
| 2408 | YHR012W | VPS29 SGDID:S000001054, Chr VIII from 129475-129522,129642-130442, Verified ORF, "Endosomal protein that is a subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde transport; forms a subcomplex with Vps35p and Vps26p that selects cargo proteins for endosome-to-Golgi retrieval" |
| 2409 | YHR013C | ARD1 SGDID:S000001055, Chr VIII from 131440-130724, reverse complement, Verified ORF, "Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing" |
| 2410 | YHR014W | SPO13 SGDID:S000001056, Chr VIII from 132040-132915, Verified ORF, "Meiosis-specific protein, involved in maintaining sister chromatid cohesion during meiosis I as well as promoting proper attachment of kinetochores to the spindle during meiosis I and meiosis II" |
| 2411 | YHR015W | MIP6 SGDID:S000001057, Chr VIII from 134547-136526, Verified ORF, "Putative RNA-binding protein, interacts with Mex67p, which is a component of the nuclear pore involved in nuclear mRNA export" |
| 2412 | YHR016C | YSC84 SGDID:S000001058, Chr VIII from 138448-138402,138233-136874, reverse complement, Verified ORF, "Protein involved in the organization of the actin cytoskeleton; contains SH3 domain similar to Rvs167p" |
| 2413 | YHR017W | YSC83 SGDID:S000001059, Chr VIII from 138687-139844, Verified ORF, "Non-essential mitochondrial protein of unknown function; mRNA induced during meiosis, peaking between mid to late prophase of meiosis I; similar to S. douglasii YSD83" |
| 2414 | YHR018C | ARG4 SGDID:S000001060, Chr VIII from 141395-140004, reverse complement, Verified ORF, "Argininosuccinate lyase, catalyzes the final step in the arginine biosynthesis pathway" |
| 2415 | YHR019C | DED81 SGDID:S000001061, Chr VIII from 143551-141887, reverse complement, Verified ORF, "Cytosolic asparaginyl-tRNA synthetase, required for protein synthesis, catalyzes the specific attachment of asparagine to its cognate tRNA" |
| 2416 | YHR020W | YHR020W SGDID:S000001062, Chr VIII from 143989-146055, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; has similarity to proline-tRNA ligase; YHR020W is an essential gene" |
| 2417 | YHR021C | RPS27B SGDID:S000001063, Chr VIII from 148662-148660,148109-147864, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Ap and has similarity to rat S27 ribosomal protein" |
| 2418 | YHR021W-A | ECM12 SGDID:S000003531, Chr VIII from 149218-149673, Uncharacterized ORF, "Non-essential protein of unknown function" |
| 2419 | YHR022C | YHR022C SGDID:S000001064, Chr VIII from 150338-149568, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YHR022C is not an essential gene." |
| 2420 | YHR022C-A | YHR022C-A SGDID:S000028645, Chr VIII from 151299-151210, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 2421 | YHR023W | MYO1 SGDID:S000001065, Chr VIII from 151659-157445, Verified ORF, "Type II myosin heavy chain, required for wild-type cytokinesis and cell separation; localizes to the actomyosin ring; binds to myosin light chains Mlc1p and Mlc2p through its IQ1 and IQ2 motifs respectively" |
| 2422 | YHR024C | MAS2 SGDID:S000001066, Chr VIII from 159185-157737, reverse complement, Verified ORF, "Larger subunit of the mitochondrial processing protease (MPP), essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins" |
| 2423 | YHR025W | THR1 SGDID:S000001067, Chr VIII from 159431-160504, Verified ORF, "Homoserine kinase, conserved protein required for threonine biosynthesis; expression is regulated by the GCN4-mediated general amino acid control pathway" |
| 2424 | YHR026W | PPA1 SGDID:S000001068, Chr VIII from 160837-161478, Verified ORF, "Subunit c'' of the vacuolar ATPase, which functions in acidification of the vacuole; one of three proteolipid subunits of the V0 domain" |
| 2425 | YHR027C | RPN1 SGDID:S000001069, Chr VIII from 164704-161723, reverse complement, Verified ORF, "Non-ATPase base subunit of the 19S regulatory particle of the 26S proteasome; may participate in the recognition of several ligands of the proteasome; contains a leucine-rich repeat (LRR) domain, a site for protein?protein interactions" |
| 2426 | YHR028C | DAP2 SGDID:S000001070, Chr VIII from 167427-164971, reverse complement, Verified ORF, "Dipeptidyl aminopeptidase, synthesized as a glycosylated precursor; localizes to the vacuolar membrane; similar to Ste13p" |
| 2427 | YHR029C | YHI9 SGDID:S000001071, Chr VIII from 168554-167670, reverse complement, Verified ORF, "Protein of unknown function; null mutant is defective in unfolded protein response; possibly involved in a membrane regulation metabolic pathway; member of the PhzF superfamily, though most likely not involved in phenazine production" |
| 2428 | YHR030C | SLT2 SGDID:S000001072, Chr VIII from 170337-168883, reverse complement, Verified ORF, "Serine/threonine MAP kinase involved in regulating the maintenance of cell wall integrity and progression through the cell cycle; regulated by the PKC1-mediated signaling pathway" |
| 2429 | YHR031C | RRM3 SGDID:S000001073, Chr VIII from 172963-170792, reverse complement, Verified ORF, "DNA helicase involved in rDNA replication and Ty1 transposition; relieves replication fork pauses at telomeric regions; structurally and functionally related to Pif1p" |
| 2430 | YHR032W | YHR032W SGDID:S000001074, Chr VIII from 173337-175082, Uncharacterized ORF, "Putative protein of unknown function; putative substrate of the cAMP-dependent protein kinase (PKA)" |
| 2431 | YHR033W | YHR033W SGDID:S000001075, Chr VIII from 175541-176812, Uncharacterized ORF, "Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm" |
| 2432 | YHR034C | PIH1 SGDID:S000001076, Chr VIII from 177992-176958, reverse complement, Verified ORF, "Protein of unresolved function; may function in protein folding and/or rRNA processing, interacts with a chaperone (Hsp82p), two chromatin remodeling factors (Rvb1p, Rvb2p) and two rRNA processing factors (Rrp43p, Nop58p)" |
| 2433 | YHR035W | YHR035W SGDID:S000001077, Chr VIII from 178212-180104, Uncharacterized ORF, "Putative protein of unknown function; not an essential gene" |
| 2434 | YHR036W | BRL1 SGDID:S000001078, Chr VIII from 180338-181753, Verified ORF, "Essential nuclear envelope integral membrane protein identified as a suppressor of a conditional mutation in the major karyopherin, CRM1; homologous to and interacts with Brr6p, a nuclear envelope protein involved in nuclear export" |
| 2435 | YHR037W | PUT2 SGDID:S000001079, Chr VIII from 181970-183697, Verified ORF, "Delta-1-pyrroline-5-carboxylate dehydrogenase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; deficiency of the human homolog causes HPII, an autosomal recessive inborn error of metabolism" |
| 2436 | YHR038W | RRF1 SGDID:S000001080, Chr VIII from 184059-184751, Verified ORF, "Mitochondrial ribosome recycling factor, essential for mitochondrial protein synthesis and for the maintenance of the respiratory function of mitochondria" |
| 2437 | YHR039C | MSC7 SGDID:S000001081, Chr VIII from 186802-184868, reverse complement, Verified ORF, "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; msc7 mutants are defective in directing meiotic recombination events to homologous chromatids" |
| 2438 | YHR039C-A | VMA10 SGDID:S000002100, Chr VIII from 187672-187670,187507-187166, reverse complement, Verified ORF, "Vacuolar H+ ATPase subunit G of the catalytic (V1) sector, involved in vacuolar acidification" |
| 2439 | YHR040W | BCD1 SGDID:S000001082, Chr VIII from 187917-189017, Verified ORF, "Essential protein required for the accumulation of box C/D snoRNA" |
| 2440 | YHR041C | SRB2 SGDID:S000001083, Chr VIII from 189857-189844,189742-189124, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; general transcription factor involved in telomere maintenance" |
| 2441 | YHR042W | NCP1 SGDID:S000001084, Chr VIII from 190536-192611, Verified ORF, "NADP-cytochrome P450 reductase; involved in ergosterol biosynthesis; associated and coordinately regulated with Erg11p" |
| 2442 | YHR043C | DOG2 SGDID:S000001085, Chr VIII from 193538-192798, reverse complement, Verified ORF, "2-deoxyglucose-6-phosphate phosphatase, member of a family of low molecular weight phosphatases, similar to Dog1p, induced by oxidative and osmotic stress, confers 2-deoxyglucose resistance when overexpressed" |
| 2443 | YHR044C | DOG1 SGDID:S000001086, Chr VIII from 194801-194061, reverse complement, Verified ORF, "2-deoxyglucose-6-phosphate phosphatase, similar to Dog2p, member of a family of low molecular weight phosphatases; confers 2-deoxyglucose resistance when overexpressed, in vivo substrate has not yet been identified" |
| 2444 | YHR045W | YHR045W SGDID:S000001087, Chr VIII from 195544-197226, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum" |
| 2445 | YHR046C | INM1 SGDID:S000001088, Chr VIII from 198278-197391, reverse complement, Verified ORF, "Inositol monophosphatase, involved in biosynthesis of inositol and in phosphoinositide second messenger signaling; INM1 expression increases in the presence of inositol and decreases upon exposure to antibipolar drugs lithium and valproate" |
| 2446 | YHR047C | AAP1 SGDID:S000001089, Chr VIII from 201303-198733, reverse complement, Verified ORF, "Arginine/alanine aminopeptidase, overproduction stimulates glycogen accumulation" |
| 2447 | YHR048W | YHK8 SGDID:S000001090, Chr VIII from 204600-206144, Uncharacterized ORF, "Presumed antiporter of the DHA1 family of multidrug resistance transporters; contains 12 predicted transmembrane spans; expression of gene is up-regulated in cells exhibiting reduced susceptibility to azoles" |
| 2448 | YHR049W | FSH1 SGDID:S000001091, Chr VIII from 206455-207186, Verified ORF, "Serine hydrolase that localizes to both the nucleus and cytoplasm; sequence is similar to Fsh2p and Fsh3p" |
| 2449 | YHR050W | SMF2 SGDID:S000001092, Chr VIII from 207648-209297, Verified ORF, "Divalent metal ion transporter involved in manganese homeostasis; has broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins" |
| 2450 | YHR050W-A | YHR050W-A SGDID:S000028832, Chr VIII from 209469-209639, Uncharacterized ORF, "Protein of unknown function; identified by expression profiling and mass spectrometry" |
| 2451 | YHR051W | COX6 SGDID:S000001093, Chr VIII from 209699-210145, Verified ORF, "Subunit VI of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; expression is regulated by oxygen levels" |
| 2452 | YHR052W | CIC1 SGDID:S000001094, Chr VIII from 210842-211972, Verified ORF, "Essential protein that interacts with proteasome components and has a potential role in proteasome substrate specificity; also copurifies with 66S pre-ribosomal particles" |
| 2453 | YHR053C | CUP1-1 SGDID:S000001095, Chr VIII from 212722-212537, reverse complement, Verified ORF, "Metallothionein, binds copper and mediates resistance to high concentrations of copper and cadmium; locus is variably amplified in different strains, with two copies, CUP1-1 and CUP1-2, in the genomic sequence reference strain S288C" |
| 2454 | YHR054C | YHR054C SGDID:S000001096, Chr VIII from 214251-213187, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 2455 | YHR055C | CUP1-2 SGDID:S000001097, Chr VIII from 214720-214535, reverse complement, Verified ORF, "Metallothionein, binds copper and mediates resistance to high concentrations of copper and cadmium; locus is variably amplified in different strains, with two copies, CUP1-1 and CUP1-2, in the genomic sequence reference strain S288C" |
| 2456 | YHR056C | RSC30 SGDID:S000001098, Chr VIII from 217836-215185, reverse complement, Verified ORF, "Component of the RSC chromatin remodeling complex; non-essential gene required for regulation of ribosomal protein genes and the cell wall/stress response; highly similar to Rsc3p; null mutants are osmosensitive" |
| 2457 | YHR057C | CPR2 SGDID:S000001099, Chr VIII from 218845-218228, reverse complement, Verified ORF, "Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; has a potential role in the secretory pathway" |
| 2458 | YHR058C | MED6 SGDID:S000001100, Chr VIII from 219886-218999, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation" |
| 2459 | YHR059W | FYV4 SGDID:S000001101, Chr VIII from 220110-220502, Verified ORF, "Protein of unknown function, required for survival upon exposure to K1 killer toxin" |
| 2460 | YHR060W | VMA22 SGDID:S000001102, Chr VIII from 220727-221272, Verified ORF, "Peripheral membrane protein that is required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the yeast endoplasmic reticulum (ER)" |
| 2461 | YHR061C | GIC1 SGDID:S000001103, Chr VIII from 222480-221536, reverse complement, Verified ORF, "Protein of unknown function involved in initiation of budding and cellular polarization, interacts with Cdc42p via the Cdc42/Rac-interactive binding (CRIB) domain" |
| 2462 | YHR062C | RPP1 SGDID:S000001104, Chr VIII from 223760-222879, reverse complement, Verified ORF, "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" |
| 2463 | YHR063C | PAN5 SGDID:S000001105, Chr VIII from 225171-224032, reverse complement, Verified ORF, "2-dehydropantoate 2-reductase, part of the pantothenic acid pathway, structurally homologous to E. coli panE" |
| 2464 | YHR064C | SSZ1 SGDID:S000001106, Chr VIII from 227143-225527, reverse complement, Verified ORF, "Hsp70 protein that interacts with Zuo1p (a DnaJ homolog) to form a ribosome-associated complex that binds the ribosome via the Zuo1p subunit; also involved in pleiotropic drug resistance via sequential activation of PDR1 and PDR5; binds ATP" |
| 2465 | YHR065C | RRP3 SGDID:S000001107, Chr VIII from 229039-227534, reverse complement, Verified ORF, "Protein involved in rRNA processing; required for maturation of the 35S primary transcript of pre-rRNA and for cleavage leading to mature 18S rRNA; homologous to eIF-4a, which is a DEAD box RNA-dependent ATPase with helicase activity" |
| 2466 | YHR066W | SSF1 SGDID:S000001108, Chr VIII from 229337-230698, Verified ORF, "Constituent of 66S pre-ribosomal particles, required for ribosomal large subunit maturation; functionally redundant with Ssf2p; member of the Brix family" |
| 2467 | YHR067W | HTD2 SGDID:S000001109, Chr VIII from 230972-231814, Verified ORF, "Mitochondrial 3-hydroxyacyl-thioester dehydratase involved in fatty acid biosynthesis, required for respiratory growth and for normal mitochondrial morphology" |
| 2468 | YHR068W | DYS1 SGDID:S000001110, Chr VIII from 232135-233298, Verified ORF, "Deoxyhypusine synthase, catalyzes formation of deoxyhypusine, the first step in hypusine biosynthesis; triggers posttranslational hypusination of translation elongation factor eIF-5A and regulates its intracellular levels; tetrameric" |
| 2469 | YHR069C | RRP4 SGDID:S000001111, Chr VIII from 234660-233581, reverse complement, Verified ORF, "3'-5' exoribonuclease involved in rRNA processing; component of the exosome 3->5 exonuclease complex with Rrp41p, Rrp42p, Rrp43p and Dis3p" |
| 2470 | YHR070W | TRM5 SGDID:S000001112, Chr VIII from 234883-236382, Verified ORF, "tRNA(m(1)G37)methyltransferase, methylates a tRNA base adjacent to the anticodon that has a role in prevention of frameshifting; highly conserved across Archaea, Bacteria, and Eukarya" |
| 2471 | YHR071W | PCL5 SGDID:S000001113, Chr VIII from 237006-237695, Verified ORF, "Cyclin, interacts with Pho85p cyclin-dependent kinase (Cdk), induced by Gcn4p at level of transcription, specifically required for Gcn4p degradation, may be sensor of cellular protein biosynthetic capacity" |
| 2472 | YHR072W | ERG7 SGDID:S000001114, Chr VIII from 239100-241295, Verified ORF, "Lanosterol synthase, an essential enzyme that catalyzes the cyclization of squalene 2,3-epoxide, a step in ergosterol biosynthesis" |
| 2473 | YHR072W-A | NOP10 SGDID:S000007455, Chr VIII from 241666-241842, Verified ORF, "Constituent of small nucleolar ribonucleoprotein particles containing H/ACA-type snoRNAs, which are required for pseudouridylation and processing of pre-18S rRNA" |
| 2474 | YHR073W | OSH3 SGDID:S000001115, Chr VIII from 242584-245574, Verified ORF, "Member of an oxysterol-binding protein family with seven members in S. cerevisiae; family members have overlapping, redundant functions in sterol metabolism and collectively perform a function essential for viability" |
| 2475 | YHR074W | QNS1 SGDID:S000001116, Chr VIII from 246195-248339, Verified ORF, "Glutamine-dependent NAD(+) synthetase, essential for the formation of NAD(+) from nicotinic acid adenine dinucleotide" |
| 2476 | YHR075C | PPE1 SGDID:S000001117, Chr VIII from 249643-248441, reverse complement, Verified ORF, "Protein with carboxyl methyl esterase activity that may have a role in demethylation of the phosphoprotein phosphatase catalytic subunit; also identified as a small subunit mitochondrial ribosomal protein" |
| 2477 | YHR076W | PTC7 SGDID:S000001118, Chr VIII from 251103-251157,251251-252227, Verified ORF, "Mitochondrially localized type 2C protein phosphatase; expression induced by growth on ethanol and by sustained osmotic stress; possible role in carbon source utilization in low oxygen environments" |
| 2478 | YHR077C | NMD2 SGDID:S000001119, Chr VIII from 255758-255753,255639-252376, reverse complement, Verified ORF, "Protein involved in the nonsense-mediated mRNA decay (NMD) pathway; interacts with Nam7p and Upf3p; involved in telomere maintenance" |
| 2479 | YHR078W | YHR078W SGDID:S000001120, Chr VIII from 256362-258020, Uncharacterized ORF, "High osmolarity-regulated gene of unknown function" |
| 2480 | YHR079C | IRE1 SGDID:S000001121, Chr VIII from 261593-258246, reverse complement, Verified ORF, "Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; Kar2p binds inactive Ire1p and releases from it upon ER stress" |
| 2481 | YHR079C-A | SAE3 SGDID:S000001957, Chr VIII from 262555-262443,262356-262194, reverse complement, Verified ORF, "Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Mei5p; proposed to be an assembly factor for Dmc1p" |
| 2482 | YHR080C | YHR080C SGDID:S000001122, Chr VIII from 266840-262803, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2483 | YHR081W | LRP1 SGDID:S000001123, Chr VIII from 267540-268094, Verified ORF, "Substrate-specific nuclear cofactor for exosome activity in the processing of stable RNAs; required for telomere length maintenance; homolog of mammalian nuclear matrix protein C1D involved in regulation of DNA repair and recombination" |
| 2484 | YHR082C | KSP1 SGDID:S000001124, Chr VIII from 271550-268461, reverse complement, Verified ORF, "Nonessential putative serine/threonine protein kinase of unknown cellular role; overproduction causes allele-specific suppression of the prp20-10 mutation" |
| 2485 | YHR083W | SAM35 SGDID:S000001125, Chr VIII from 272629-273618, Verified ORF, "Essential component of the sorting and assembly machinery (SAM complex or TOB complex) of the mitochondrial outer membrane, which binds precursors of beta-barrel proteins and facilitates their insertion into the outer membrane" |
| 2486 | YHR084W | STE12 SGDID:S000001126, Chr VIII from 274176-276242, Verified ORF, "Transcription factor that is activated by a MAP kinase signaling cascade, activates genes involved in mating or pseudohyphal/invasive growth pathways; cooperates with Tec1p transcription factor to regulate genes specific for invasive growth" |
| 2487 | YHR085W | IPI1 SGDID:S000001127, Chr VIII from 276766-277770, Verified ORF, "Essential component of the Rix1 complex (with Rix1p and Ipi3p) that is required for processing of ITS2 sequences from 35S pre-rRNA; Rix1 complex associates with Mdn1p in pre-60S ribosomal particles" |
| 2488 | YHR086W | NAM8 SGDID:S000001128, Chr VIII from 278155-279726, Verified ORF, "RNA binding protein, component of the U1 snRNP protein; mutants are defective in meiotic recombination and in formation of viable spores, involved in the formation of DSBs through meiosis-specific splicing of MER2 pre-mRNA" |
| 2489 | YHR086W-A | YHR086W-A SGDID:S000028552, Chr VIII from 280233-280394, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 2490 | YHR087W | YHR087W SGDID:S000001129, Chr VIII from 280822-281157, Verified ORF, "Protein of unknown function involved in RNA metabolism; has structural similarity to SBDS, the human protein mutated in Shwachman-Diamond Syndrome (the yeast SBDS ortholog = SDO1); null mutation suppresses cdc13-1 temperature sensitivity" |
| 2491 | YHR088W | RPF1 SGDID:S000001130, Chr VIII from 281497-282384, Verified ORF, "Nucleolar protein involved in the assembly of the large ribosomal subunit; constituent of 66S pre-ribosomal particles; contains a sigma(70)-like motif, which is thought to bind RNA" |
| 2492 | YHR089C | GAR1 SGDID:S000001131, Chr VIII from 283300-282683, reverse complement, Verified ORF, "Protein component of the H/ACA snoRNP pseudouridylase complex, involved in the modification and cleavage of the 18S pre-rRNA" |
| 2493 | YHR090C | YNG2 SGDID:S000001132, Chr VIII from 284627-283779, reverse complement, Verified ORF, "Subunit of the NuA4 histone acetyltransferase complex that acetylates histone H4 and H2A; has similarity to the human tumor suppressor ING1" |
| 2494 | YHR091C | MSR1 SGDID:S000001133, Chr VIII from 286772-284841, reverse complement, Verified ORF, "Mitochondrial arginyl-tRNA synthetase" |
| 2495 | YHR092C | HXT4 SGDID:S000001134, Chr VIII from 288814-287132, reverse complement, Verified ORF, "High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose" |
| 2496 | YHR094C | HXT1 SGDID:S000001136, Chr VIII from 292628-290916, reverse complement, Verified ORF, "Low-affinity glucose transporter of the major facilitator superfamily, expression is induced by Hxk2p in the presence of glucose and repressed by Rgt1p when glucose is limiting" |
| 2497 | YHR096C | HXT5 SGDID:S000001138, Chr VIII from 296450-294672, reverse complement, Verified ORF, "Hexose transporter with moderate affinity for glucose, induced in the presence of non-fermentable carbon sources, induced by a decrease in growth rate, contains an extended N-terminal domain relative to other HXTs" |
| 2498 | YHR097C | YHR097C SGDID:S000001139, Chr VIII from 298612-298488,298363-297388, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus" |
| 2499 | YHR098C | SFB3 SGDID:S000001140, Chr VIII from 301937-299148, reverse complement, Verified ORF, "Member of the Sec24p family; forms a complex, with Sec23p, that is involved in sorting of Pma1p into COPII vesicles; peripheral ER membrane protein; potential Cdc28p substrate" |
| 2500 | YHR099W | TRA1 SGDID:S000001141, Chr VIII from 302764-313998, Verified ORF, "Subunit of SAGA and NuA4 histone acetyltransferase complexes; interacts with acidic activators (e.g., Gal4p) which leads to transcription activation; similar to human TRRAP, which is a cofactor for c-Myc mediated oncogenic transformation" |
| 2501 | YHR100C | YHR100C SGDID:S000001142, Chr VIII from 314676-314119, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2502 | YHR101C | BIG1 SGDID:S000001143, Chr VIII from 315971-315862,315774-314877, reverse complement, Verified ORF, "Integral membrane protein of the endoplasmic reticulum, required for normal content of cell wall beta-1,6-glucan" |
| 2503 | YHR102W | KIC1 SGDID:S000001144, Chr VIII from 316575-319817, Verified ORF, "Protein kinase of the PAK/Ste20 kinase family, required for cell integrity possibly through regulating 1,6-beta-glucan levels in the wall; physically interacts with Cdc31p (centrin), which is a component of the spindle pole body" |
| 2504 | YHR103W | SBE22 SGDID:S000001145, Chr VIII from 320417-322975, Verified ORF, "Protein involved in the transport of cell wall components from the Golgi to the cell surface; similar in structure and functionally redundant with Sbe2p; involved in bud growth" |
| 2505 | YHR104W | GRE3 SGDID:S000001146, Chr VIII from 323412-324395, Verified ORF, "Aldose reductase involved in methylglyoxal, d-xylose and arabinose metabolism; stress induced (osmotic, ionic, oxidative, heat shock, starvation and heavy metals); regulated by the HOG pathway" |
| 2506 | YHR105W | YPT35 SGDID:S000001147, Chr VIII from 324769-325413, Verified ORF, "Endosomal protein of unknown function that contains a phox (PX) homology domain and binds to both phosphatidylinositol-3-phosphate (PtdIns(3)P) and proteins involved in ER-Golgi or vesicular transport" |
| 2507 | YHR106W | TRR2 SGDID:S000001148, Chr VIII from 325601-326629, Verified ORF, "Mitochondrial thioredoxin reductase involved in protection against oxidative stress, required with Glr1p to maintain the redox state of Trx3p; contains active-site motif (CAVC) present in prokaryotic orthologs; binds NADPH and FAD" |
| 2508 | YHR107C | CDC12 SGDID:S000001149, Chr VIII from 328039-326816, reverse complement, Verified ORF, "Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM" |
| 2509 | YHR108W | GGA2 SGDID:S000001150, Chr VIII from 328306-330063, Verified ORF, "Golgi-localized protein with homology to gamma-adaptin, interacts with and regulates Arf1p and Arf2p in a GTP-dependent manner in order to facilitate traffic through the late Golgi" |
| 2510 | YHR109W | CTM1 SGDID:S000001151, Chr VIII from 330313-332070, Verified ORF, "Cytochrome c lysine methyltransferase, trimethylates residue 72 of apo-cytochrome c (Cyc1p) in the cytosol; not required for normal respiratory growth" |
| 2511 | YHR110W | ERP5 SGDID:S000001152, Chr VIII from 332285-332923, Verified ORF, "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport" |
| 2512 | YHR111W | UBA4 SGDID:S000001153, Chr VIII from 333075-334397, Verified ORF, "Protein that activates Urm1p before its conjugation to proteins (urmylation); one target is the thioredoxin peroxidase Ahp1p, suggesting a role of urmylation in the oxidative stress response" |
| 2513 | YHR112C | YHR112C SGDID:S000001154, Chr VIII from 335666-334530, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 2514 | YHR113W | YHR113W SGDID:S000001155, Chr VIII from 336340-337812, Verified ORF, "Cytoplasmic aspartyl aminopeptidase; cleaves unblocked N-terminal acidic amino acid residues from peptide substrates; forms a 12 subunit homo-oligomeric complex; M18 metalloprotease family member; may interact with ribosomes" |
| 2515 | YHR114W | BZZ1 SGDID:S000001156, Chr VIII from 338086-339987, Verified ORF, "SH3 domain protein implicated in the regulation of actin polymerization, able to recruit actin polymerization machinery through its SH3 domains, colocalizes with cortical actin patches and Las17p, interacts with type I myosins" |
| 2516 | YHR115C | DMA1 SGDID:S000001157, Chr VIII from 341362-340112, reverse complement, Verified ORF, "Protein involved in ubiquitin ligation; plays a role in regulating spindle position and orientation; functionally redundant with Dma2p; orthologous to human RNF8 protein, also has sequence similarity to human Chfr." |
| 2517 | YHR116W | COX23 SGDID:S000001158, Chr VIII from 341668-342123, Verified ORF, "Mitochondrial intermembrane space protein that functions in mitochondrial copper homeostasis, essential for functional cytochrome oxidase expression; homologous to Cox17p" |
| 2518 | YHR117W | TOM71 SGDID:S000001159, Chr VIII from 342352-344271, Verified ORF, "Mitochondrial outer membrane protein with similarity to Tom70p; probable minor component of the TOM (translocase of outer membrane) complex responsible for recognition and import of mitochondrially directed proteins" |
| 2519 | YHR118C | ORC6 SGDID:S000001160, Chr VIII from 345631-344324, reverse complement, Verified ORF, "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; phosphorylated by Cdc28p" |
| 2520 | YHR119W | SET1 SGDID:S000001161, Chr VIII from 346046-349288, Verified ORF, "Histone methyltransferase, subunit of the COMPASS (Set1C) complex which methylates histone H3 on lysine 4; required in transcriptional silencing near telomeres and at the silent mating type loci; contains a SET domain" |
| 2521 | YHR120W | MSH1 SGDID:S000001162, Chr VIII from 349577-352456, Verified ORF, "DNA-binding protein of the mitochondria involved in repair of mitochondrial DNA, has ATPase activity and binds to DNA mismatches; has homology to E. coli MutS; transcription is induced during meiosis" |
| 2522 | YHR121W | LSM12 SGDID:S000001163, Chr VIII from 352759-353322, Verified ORF, "Protein of unknown function that may function in RNA processing; interacts with Pbp1p and Pbp4p and associates with ribosomes; contains an RNA-binding LSM domain and an AD domain; GFP-fusion protein is induced by the DNA-damaging agent MMS" |
| 2523 | YHR122W | YHR122W SGDID:S000001164, Chr VIII from 353628-354323, Verified ORF, "Protein of unknown function required for establishment of sister chromatid cohesion; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; may be involved in transcription; YHR122W is an essential gene" |
| 2524 | YHR123W | EPT1 SGDID:S000001165, Chr VIII from 354818-354867,354959-356084, Verified ORF, "sn-1,2-diacylglycerol ethanolamine- and cholinephosphotranferase; not essential for viability" |
| 2525 | YHR124W | NDT80 SGDID:S000001166, Chr VIII from 356564-358447, Verified ORF, "Meiosis-specific transcription factor required for exit from pachytene and for full meiotic recombination; activates middle sporulation genes; competes with Sum1p for binding to promoters containing middle sporulation elements (MSE)" |
| 2526 | YHR126C | YHR126C SGDID:S000001168, Chr VIII from 360184-359705, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; transcription dependent upon Azf1p" |
| 2527 | YHR127W | YHR127W SGDID:S000001169, Chr VIII from 360916-361647, Verified ORF, "Protein of unknown function; localizes to the nucleus" |
| 2528 | YHR128W | FUR1 SGDID:S000001170, Chr VIII from 362118-362768, Verified ORF, "Uracil phosphoribosyltransferase, synthesizes UMP from uracil; involved in the pyrimidine salvage pathway" |
| 2529 | YHR129C | ARP1 SGDID:S000001171, Chr VIII from 364156-363002, reverse complement, Verified ORF, "Actin-related protein of the dynactin complex; required for spindle orientation and nuclear migration; putative ortholog of mammalian centractin" |
| 2530 | YHR131C | YHR131C SGDID:S000001173, Chr VIII from 367895-365343, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 2531 | YHR132C | ECM14 SGDID:S000001174, Chr VIII from 369797-368505, reverse complement, Verified ORF, "Putative metalloprotease with similarity to the zinc carboxypeptidase family, required for normal cell wall assembly" |
| 2532 | YHR132W-A | YHR132W-A SGDID:S000007496, Chr VIII from 370057-370452, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
| 2533 | YHR133C | NSG1 SGDID:S000001175, Chr VIII from 371600-370725, reverse complement, Verified ORF, "Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins" |
| 2534 | YHR134W | WSS1 SGDID:S000001176, Chr VIII from 371752-372561, Verified ORF, "Sumoylated protein of unknown function, identified based on genetic interactions with SMT3; UV-sensitive mutant phenotype and genetic interactions suggest a role in the DNA damage response, processing stalled or collapsed replication forks" |
| 2535 | YHR135C | YCK1 SGDID:S000001177, Chr VIII from 374313-372697, reverse complement, Verified ORF, "Palmitoylated, plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck2p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck2p" |
| 2536 | YHR136C | SPL2 SGDID:S000001178, Chr VIII from 375103-374657, reverse complement, Verified ORF, "Protein with similarity to cyclin-dependent kinase inhibitors, overproduction suppresses a plc1 null mutation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 2537 | YHR137W | ARO9 SGDID:S000001179, Chr VIII from 375712-377253, Verified ORF, "Aromatic aminotransferase II, catalyzes the first step of tryptophan, phenylalanine, and tyrosine catabolism" |
| 2538 | YHR138C | YHR138C SGDID:S000001180, Chr VIII from 377702-377358, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; has similarity to Pbi2p; double null mutant lacking Pbi2p and Yhr138p exhibits highly fragmented vacuoles" |
| 2539 | YHR139C | SPS100 SGDID:S000001181, Chr VIII from 379202-378222, reverse complement, Verified ORF, "Protein required for spore wall maturation; expressed during sporulation; may be a component of the spore wall" |
| 2540 | YHR140W | YHR140W SGDID:S000001182, Chr VIII from 380575-381294, Uncharacterized ORF, "Putative integral membrane protein of unknown function" |
| 2541 | YHR141C | RPL42B SGDID:S000001183, Chr VIII from 382754-382751,382309-381993, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, identical to Rpl42Ap and has similarity to rat L44; required for propagation of the killer toxin-encoding M1 double-stranded RNA satellite of the L-A double-stranded RNA virus" |
| 2542 | YHR142W | CHS7 SGDID:S000001184, Chr VIII from 383541-384491, Verified ORF, "Protein of unknown function, involved in chitin biosynthesis by regulating Chs3p export from the ER" |
| 2543 | YHR143W | DSE2 SGDID:S000001186, Chr VIII from 385513-386490, Verified ORF, "Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother; expression is repressed by cAMP" |
| 2544 | YHR143W-A | RPC10 SGDID:S000001185, Chr VIII from 387236-387448, Verified ORF, "RNA polymerase subunit, found in RNA polymerase complexes I, II, and III" |
| 2545 | YHR144C | DCD1 SGDID:S000001187, Chr VIII from 388729-387791, reverse complement, Verified ORF, "Deoxycytidine monophosphate (dCMP) deaminase required for dCTP and dTTP synthesis; expression is NOT cell cycle regulated" |
| 2546 | YHR146W | CRP1 SGDID:S000001189, Chr VIII from 390303-391700, Verified ORF, "Protein that binds to cruciform DNA structures" |
| 2547 | YHR147C | MRPL6 SGDID:S000001190, Chr VIII from 393286-392642, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 2548 | YHR148W | IMP3 SGDID:S000001191, Chr VIII from 393537-394088, Verified ORF, "Component of the SSU processome, which is required for pre-18S rRNA processing, essential protein that interacts with Mpp10p and mediates interactions of Imp4p and Mpp10p with U3 snoRNA" |
| 2549 | YHR149C | SKG6 SGDID:S000001192, Chr VIII from 396662-394458, reverse complement, Verified ORF, "Integral membrane protein that localizes primarily to growing sites such as the bud tip or the cell periphery; potential Cdc28p substrate; Skg6p interacts with Zds1p and Zds2p" |
| 2550 | YHR150W | PEX28 SGDID:S000001193, Chr VIII from 397254-398993, Verified ORF, "Peroxisomal integral membrane peroxin, involved in the regulation of peroxisomal size, number and distribution; genetic interactions suggest that Pex28p and Pex29p act at steps upstream of those mediated by Pex30p, Pex31p, and Pex32p" |
| 2551 | YHR151C | YHR151C SGDID:S000001194, Chr VIII from 400851-399271, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YHR151C is synthetically sick with cdc13-1" |
| 2552 | YHR152W | SPO12 SGDID:S000001195, Chr VIII from 401437-401958, Verified ORF, "Nucleolar protein of unknown function, positive regulator of mitotic exit; involved in regulating release of Cdc14p from the nucleolus in early anaphase, may play similar role in meiosis" |
| 2553 | YHR153C | SPO16 SGDID:S000001196, Chr VIII from 402685-402089, reverse complement, Verified ORF, "Protein of unknown function, required for spore formation" |
| 2554 | YHR154W | RTT107 SGDID:S000001197, Chr VIII from 402969-406181, Verified ORF, "Protein implicated in Mms22-dependent DNA repair during S phase, DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition" |
| 2555 | YHR155W | YSP1 SGDID:S000001198, Chr VIII from 407106-410792, Verified ORF, "Mitochondrial protein with a potential role in promoting mitochondrial fragmentation during programmed cell death in response to high levels of alpha-factor mating pheromone or the drug amiodarone" |
| 2556 | YHR156C | LIN1 SGDID:S000001199, Chr VIII from 412409-411387, reverse complement, Verified ORF, "Non-essential component of U5 snRNP; nuclear protein; physically interacts with Irr1p of cohesin complex; may link together proteins involved in chromosome segregation, mRNA splicing and DNA replication" |
| 2557 | YHR157W | REC104 SGDID:S000001200, Chr VIII from 412910-413458, Verified ORF, "Protein involved in early stages of meiotic recombination; required for meiotic crossing over; forms a complex with Rec102p and Spo11p necessary during the initiation of recombination" |
| 2558 | YHR158C | KEL1 SGDID:S000001201, Chr VIII from 417182-413688, reverse complement, Verified ORF, "Protein required for proper cell fusion and cell morphology; functions in a complex with Kel2p to negatively regulate mitotic exit, interacts with Tem1p and Lte1p; localizes to regions of polarized growth; potential Cdc28p substrate" |
| 2559 | YHR159W | YHR159W SGDID:S000001202, Chr VIII from 417552-419066, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; potential Cdc28p substrate" |
| 2560 | YHR160C | PEX18 SGDID:S000001203, Chr VIII from 420075-419224, reverse complement, Verified ORF, "Peroxin required for targeting of peroxisomal matrix proteins containing PTS2; interacts with Pex7p; partially redundant with Pex21p" |
| 2561 | YHR161C | YAP1801 SGDID:S000001204, Chr VIII from 422289-420376, reverse complement, Verified ORF, "Protein involved in clathrin cage assembly; binds Pan1p and clathrin; homologous to Yap1802p, member of the AP180 protein family" |
| 2562 | YHR162W | YHR162W SGDID:S000001205, Chr VIII from 423075-423464, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion" |
| 2563 | YHR163W | SOL3 SGDID:S000001206, Chr VIII from 423726-424475, Verified ORF, "6-phosphogluconolactonase, catalyzes the second step of the pentose phosphate pathway; weak multicopy suppressor of los1-1 mutation; homologous to Sol2p and Sol1p" |
| 2564 | YHR164C | DNA2 SGDID:S000001207, Chr VIII from 429180-424612, reverse complement, Verified ORF, "Essential tripartite DNA replication factor with single-stranded DNA-dependent ATPase, ATP-dependent nuclease, and helicase activities; required for Okazaki fragment processing; involved in DNA repair pathways; potential Cdc28p substrate" |
| 2565 | YHR165C | PRP8 SGDID:S000001208, Chr VIII from 436950-429709, reverse complement, Verified ORF, "Component of the U4/U6-U5 snRNP complex, involved in the second catalytic step of splicing; mutations of human Prp8 cause retinitis pigmentosa" |
| 2566 | YHR166C | CDC23 SGDID:S000001209, Chr VIII from 439052-437172, reverse complement, Verified ORF, "Subunit of the anaphase-promoting complex/cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" |
| 2567 | YHR167W | THP2 SGDID:S000001210, Chr VIII from 439344-440129, Verified ORF, "Subunit of the THO complex, which connects transcription elongation and mitotic recombination, and of the TREX complex, which is recruited to activated genes and couples transcription to mRNA export; involved in telomere maintenance" |
| 2568 | YHR168W | MTG2 SGDID:S000001211, Chr VIII from 440379-441878, Verified ORF, "Putative GTPase, member of the Obg family; peripheral protein of the mitochondrial inner membrane that associates with the large ribosomal subunit; required for mitochondrial translation, possibly via a role in ribosome assembly" |
| 2569 | YHR169W | DBP8 SGDID:S000001212, Chr VIII from 442182-443477, Verified ORF, "Putative ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 40S ribosomal subunit" |
| 2570 | YHR170W | NMD3 SGDID:S000001213, Chr VIII from 443829-445385, Verified ORF, "Protein involved in nuclear export of the large ribosomal subunit; acts as a Crm1p-dependent adapter protein for export of nascent ribosomal subunits through the nuclear pore complex" |
| 2571 | YHR171W | ATG7 SGDID:S000001214, Chr VIII from 445713-447605, Verified ORF, "Autophagy-related protein and dual specificity member of the E1 family of ubiquitin-activating enzymes; mediates the conjugation of Atg12p with Atg5p and Atg8p with phosphatidylethanolamine, required steps in autophagosome formation" |
| 2572 | YHR172W | SPC97 SGDID:S000001215, Chr VIII from 448335-450806, Verified ORF, "Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque" |
| 2573 | YHR174W | ENO2 SGDID:S000001217, Chr VIII from 451327-452640, Verified ORF, "Enolase II, a phosphopyruvate hydratase that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate during glycolysis and the reverse reaction during gluconeogenesis; expression is induced in response to glucose" |
| 2574 | YHR175W | CTR2 SGDID:S000001218, Chr VIII from 452872-453441, Verified ORF, "Putative low-affinity copper transporter of the vacuolar membrane; mutation confers resistance to toxic copper concentrations, while overexpression confers resistance to copper starvation" |
| 2575 | YHR175W-A | YHR175W-A SGDID:S000028553, Chr VIII from 453558-453707, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 2576 | YHR176W | FMO1 SGDID:S000001219, Chr VIII from 454229-455527, Verified ORF, "Flavin-containing monooxygenase, localized to the cytoplasmic face of the ER membrane; catalyzes oxidation of biological thiols to maintain the ER redox buffer ratio for correct folding of disulfide-bonded proteins" |
| 2577 | YHR177W | YHR177W SGDID:S000001220, Chr VIII from 456591-457952, Uncharacterized ORF, "Putative protein of unknown function" |
| 2578 | YHR178W | STB5 SGDID:S000001221, Chr VIII from 459299-461530, Verified ORF, "Activator of multidrug resistance genes, forms a heterodimer with Pdr1p; contains a Zn(II)2Cys6 zinc finger domain that interacts with a PDRE (pleotropic drug resistance element) in vitro; binds Sin3p in a two-hybrid assay" |
| 2579 | YHR179W | OYE2 SGDID:S000001222, Chr VIII from 462502-463704, Verified ORF, "Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye3p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism" |
| 2580 | YHR181W | SVP26 SGDID:S000001224, Chr VIII from 467228-467914, Verified ORF, "Integral membrane protein of the early Golgi apparatus and endoplasmic reticulum, involved in COP II vesicle transport; may also function to promote retention of proteins in the early Golgi compartment" |
| 2581 | YHR182W | YHR182W SGDID:S000001225, Chr VIII from 468219-470576, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and cytoplasm" |
| 2582 | YHR183W | GND1 SGDID:S000001226, Chr VIII from 470960-472429, Verified ORF, "6-phosphogluconate dehydrogenase (decarboxylating), catalyzes an NADPH regenerating reaction in the pentose phosphate pathway; required for growth on D-glucono-delta-lactone and adaptation to oxidative stress" |
| 2583 | YHR184W | SSP1 SGDID:S000001227, Chr VIII from 472744-474459, Verified ORF, "Protein involved in the control of meiotic nuclear division and coordination of meiosis with spore formation; transcription is induced midway through meiosis" |
| 2584 | YHR185C | PFS1 SGDID:S000001228, Chr VIII from 475340-474627, reverse complement, Verified ORF, "Sporulation protein required for prospore membrane formation at selected spindle poles, ensures functionality of all four spindle pole bodies during meiosis II; not required for meiotic recombination or meiotic chromosome segregation" |
| 2585 | YHR186C | KOG1 SGDID:S000001229, Chr VIII from 480672-475999, reverse complement, Verified ORF, "Subunit of TORC1, a rapamycin-sensitive complex involved in growth control that contains Tor1p or Tor2p, Lst8p and Tco89p; contains four HEAT repeats and seven WD-40 repeats; may act as a scaffold protein to couple TOR and its effectors" |
| 2586 | YHR187W | IKI1 SGDID:S000001230, Chr VIII from 480990-481919, Verified ORF, "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; iki1 mutations confer resistance to the K. lactis toxin zymocin" |
| 2587 | YHR188C | GPI16 SGDID:S000001231, Chr VIII from 483837-482005, reverse complement, Verified ORF, "Transmembrane protein subunit of the glycosylphosphatidylinositol transamidase complex that adds GPIs to newly synthesized proteins; human PIG-Tp homolog" |
| 2588 | YHR189W | PTH1 SGDID:S000001232, Chr VIII from 484028-484600, Verified ORF, "One of two (see also PTH2) mitochondrially-localized peptidyl-tRNA hydrolases; dispensable for cell growth and for mitochondrial respiration" |
| 2589 | YHR190W | ERG9 SGDID:S000001233, Chr VIII from 484845-486179, Verified ORF, "Farnesyl-diphosphate farnesyl transferase (squalene synthase), joins two farnesyl pyrophosphate moieties to form squalene in the sterol biosynthesis pathway" |
| 2590 | YHR191C | CTF8 SGDID:S000001234, Chr VIII from 486631-486230, reverse complement, Verified ORF, "Subunit of a complex with Ctf18p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion" |
| 2591 | YHR192W | YHR192W SGDID:S000001235, Chr VIII from 486826-487662, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS" |
| 2592 | YHR193C | EGD2 SGDID:S000001236, Chr VIII from 488236-487712, reverse complement, Verified ORF, "Alpha subunit of the heteromeric nascent polypeptide-associated complex (NAC) involved in protein sorting and translocation, associated with cytoplasmic ribosomes" |
| 2593 | YHR194W | MDM31 SGDID:S000001237, Chr VIII from 488657-490396, Verified ORF, "Mitochondrial inner membrane protein with similarity to Mdm32p, required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34" |
| 2594 | YHR195W | NVJ1 SGDID:S000001238, Chr VIII from 490747-491712, Verified ORF, "Nuclear envelope protein that interacts with the vacuolar membrane protein Vac8p to promote formation of nucleus-vacuole junctions during piecemeal microautophagy of the nucleus (PMN)" |
| 2595 | YHR196W | UTP9 SGDID:S000001239, Chr VIII from 491931-493658, Verified ORF, "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" |
| 2596 | YHR197W | RIX1 SGDID:S000001240, Chr VIII from 493896-496187, Verified ORF, "Essential component of the Rix1 complex (Rix1p, Ipi1p, Ipi3p) that is required for processing of ITS2 sequences from 35S pre-rRNA; Rix1 complex associates with Mdn1p in pre-60S ribosomal particles" |
| 2597 | YHR198C | YHR198C SGDID:S000001241, Chr VIII from 497280-496315, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss (petite formation)" |
| 2598 | YHR199C | YHR199C SGDID:S000001242, Chr VIII from 498422-497490, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss (petite formation)" |
| 2599 | YHR199C-A | YHR199C-A SGDID:S000029704, Chr VIII from 498859-498787,498719-498571, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; transcribed sequence appears to contain an intron" |
| 2600 | YHR200W | RPN10 SGDID:S000001243, Chr VIII from 499079-499885, Verified ORF, "Non-ATPase base subunit of the 19S regulatory particle (RP) of the 26S proteasome; N-terminus plays a role in maintaining the structural integrity of the RP; binds selectively to polyubiquitin chains; homolog of the mammalian S5a protein" |
| 2601 | YHR201C | PPX1 SGDID:S000001244, Chr VIII from 501143-499950, reverse complement, Verified ORF, "Exopolyphosphatase, hydrolyzes inorganic polyphosphate (poly P) into Pi residues; located in the cytosol, plasma membrane, and mitochondrial matrix" |
| 2602 | YHR202W | YHR202W SGDID:S000001245, Chr VIII from 502388-504196, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole, while HA-tagged protein is found in the soluble fraction, suggesting cytoplasmic localization" |
| 2603 | YHR203C | RPS4B SGDID:S000001246, Chr VIII from 505530-505517,505247-504476, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; identical to Rps4Ap and has similarity to rat S4 ribosomal protein" |
| 2604 | YHR204W | MNL1 SGDID:S000001247, Chr VIII from 506319-508709, Verified ORF, "Alpha mannosidase-like protein of the endoplasmic reticulum required for degradation of glycoproteins but not for processing of N-linked oligosaccharides" |
| 2605 | YHR205W | SCH9 SGDID:S000001248, Chr VIII from 509363-511837, Verified ORF, "Protein kinase involved in transcriptional activation of osmostress-responsive genes; regulates G1 progression, cAPK activity, nitrogen activation of the FGM pathway; involved in life span regulation; homologous to mammalian Akt/PKB" |
| 2606 | YHR206W | SKN7 SGDID:S000001249, Chr VIII from 512732-514600, Verified ORF, "Nuclear response regulator and transcription factor, part of a branched two-component signaling system; required for optimal induction of heat-shock genes in response to oxidative stress; involved in osmoregulation" |
| 2607 | YHR207C | SET5 SGDID:S000001250, Chr VIII from 516485-514905, reverse complement, Verified ORF, "Zinc-finger protein of unknown function, contains one canonical and two unusual fingers in unusual arrangements; deletion enhances replication of positive-strand RNA virus" |
| 2608 | YHR208W | BAT1 SGDID:S000001251, Chr VIII from 517532-518713, Verified ORF, "Mitochondrial branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during logarithmic phase and repressed during stationary phase" |
| 2609 | YHR209W | YHR209W SGDID:S000001252, Chr VIII from 519437-520312, Uncharacterized ORF, "Putative S-adenosylmethionine-dependent methyltransferase; mediates cantharidin resistance" |
| 2610 | YHR210C | YHR210C SGDID:S000001253, Chr VIII from 521737-520712, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene; highly expressed under anaeorbic conditions; sequence similarity to aldose 1-epimerases such as GAL10" |
| 2611 | YHR211W | FLO5 SGDID:S000001254, Chr VIII from 525392-528619, Verified ORF, "Lectin-like cell wall protein (flocculin) involved in flocculation, binds to mannose chains on the surface of other cells, confers floc-forming ability that is chymotrypsin resistant but heat labile; similar to Flo1p" |
| 2612 | YHR212W-A | YHR212W-A SGDID:S000028650, Chr VIII from 538742-538945, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 2613 | YHR213W | YHR213W SGDID:S000001256, Chr VIII from 539151-539747, Uncharacterized ORF, "Putative protein of unknown function" |
| 2614 | YHR213W-A | YHR213W-A SGDID:S000028651, Chr VIII from 540549-540782, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 2615 | YHR213W-B | YHR213W-B SGDID:S000028652, Chr VIII from 540800-541099, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 2616 | YHR214C-B | YHR214C-B SGDID:S000003534, Chr VIII from 549346-547931,547929-543964, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 2617 | YHR214C-C | YHR214C-C SGDID:S000007421, Chr VIII from 549346-547910, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 2618 | YHR214C-D | YHR214C-D SGDID:S000028653, Chr VIII from 550941-550648, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 2619 | YHR214C-E | YHR214C-E SGDID:S000028654, Chr VIII from 551499-551200, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 2620 | YHR214W | YHR214W SGDID:S000001257, Chr VIII from 541651-542262, Uncharacterized ORF, "Putative protein of unknown function; predicted to be a glycosylphosphatidylinositol-modified (GPI) protein" |
| 2621 | YHR215W | PHO12 SGDID:S000001258, Chr VIII from 552099-553502, Verified ORF, "One of three repressible acid phosphatases, a glycoprotein that is transported to the cell surface by the secretory pathway; nearly identical to Pho11p; upregulated by phosphate starvation" |
| 2622 | YHR216W | IMD2 SGDID:S000001259, Chr VIII from 554396-555967, Verified ORF, "Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, expression is induced by mycophenolic acid resulting in resistance to the drug, expression is repressed by nutrient limitation" |
| 2623 | YHR218W | YHR218W SGDID:S000001261, Chr VIII from 558014-558615,558715-559924, Uncharacterized ORF, "Helicase-like protein encoded within the telomeric Y' element" |
| 2624 | YHR219W | YHR219W SGDID:S000001262, Chr VIII from 560173-562047, Uncharacterized ORF, "Putative protein of unknown function with similarity to helicases; located in the telomere region on the right arm of chromosome VIII" |
| 2625 | YIL001W | YIL001W SGDID:S000001263, Chr IX from 353937-355478, Uncharacterized ORF, "Hypothetical protein" |
| 2626 | YIL002C | INP51 SGDID:S000001264, Chr IX from 353428-350588, reverse complement, Verified ORF, "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase, synaptojanin-like protein with an N-terminal Sac1 domain, plays a role in phosphatidylinositol 4,5-bisphosphate homeostasis and in endocytosis; null mutation confers cold-tolerant growth" |
| 2627 | YIL002W-A | YIL002W-A SGDID:S000028835, Chr IX from 350298-350507, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 2628 | YIL003W | CFD1 SGDID:S000001265, Chr IX from 349119-350000, Verified ORF, "Highly conserved, iron-sulfur cluster binding protein localized in the cytoplasm; forms a complex with Nbp35p that is involved in iron-sulfur protein assembly in the cytosol" |
| 2629 | YIL004C | BET1 SGDID:S000001266, Chr IX from 348502-348492,348360-347943, reverse complement, Verified ORF, "Type II membrane protein required for vesicular transport between the endoplasmic reticulum and Golgi complex; v-SNARE with similarity to synaptobrevins" |
| 2630 | YIL005W | EPS1 SGDID:S000001267, Chr IX from 345689-347794, Verified ORF, "ER protein with chaperone and co-chaperone activity, involved in retention of resident ER proteins; has a role in recognizing proteins targeted for ER-associated degradation (ERAD), member of the protein disulfide isomerase family" |
| 2631 | YIL006W | YIA6 SGDID:S000001268, Chr IX from 344059-345180, Verified ORF, "Mitochondrial NAD+ transporter, involved in the transport of NAD+ into the mitochondria (see also YEA6); member of the mitochondrial carrier subfamily; disputed role as a pyruvate transporter; has putative mouse and human orthologs" |
| 2632 | YIL007C | NAS2 SGDID:S000001269, Chr IX from 343653-342991, reverse complement, Verified ORF, "Protein with similarity to the p27 subunit of mammalian proteasome modulator; not essential; interacts with Rpn4p" |
| 2633 | YIL008W | URM1 SGDID:S000001270, Chr IX from 342533-342832, Verified ORF, "Ubiquitin-like protein with weak sequence similarity to ubiquitin; depends on the E1-like activating enzyme Uba4p; molecular function of the Urm1p pathway is unknown, but it is required for normal growth, particularly at high temperature" |
| 2634 | YIL009C-A | EST3 SGDID:S000006432, Chr IX from 336209-335934,335932-335663, reverse complement, Verified ORF, "Component of the telomerase holoenzyme, involved in telomere replication" |
| 2635 | YIL009W | FAA3 SGDID:S000001271, Chr IX from 339341-341425, Verified ORF, "Long chain fatty acyl-CoA synthetase, has a preference for C16 and C18 fatty acids; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery" |
| 2636 | YIL010W | DOT5 SGDID:S000001272, Chr IX from 334879-335526, Verified ORF, "Nuclear thiol peroxidase which functions as an alkyl-hydroperoxide reductase during post-diauxic growth" |
| 2637 | YIL011W | TIR3 SGDID:S000001273, Chr IX from 333724-334533, Verified ORF, "Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth" |
| 2638 | YIL013C | PDR11 SGDID:S000001275, Chr IX from 332440-328205, reverse complement, Verified ORF, "ATP-binding cassette (ABC) transporter, multidrug transporter involved in multiple drug resistance; mediates sterol uptake when sterol biosynthesis is compromisedregulated by Pdr1p; required for anaerobic growth" |
| 2639 | YIL014C-A | YIL014C-A SGDID:S000003536, Chr IX from 325524-325210, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 2640 | YIL014W | MNT3 SGDID:S000001276, Chr IX from 326101-327993, Verified ORF, "Alpha-1,3-mannosyltransferase, adds the fourth and fifth alpha-1,3-linked mannose residues to O-linked glycans during protein O-glycosylation" |
| 2641 | YIL015W | BAR1 SGDID:S000001277, Chr IX from 322340-324103, Verified ORF, "Aspartyl protease secreted into the periplasmic space of mating type a cells, helps cells find mating partners, cleaves and inactivates alpha factor allowing cells to recover from alpha-factor-induced cell cycle arrest" |
| 2642 | YIL016W | SNL1 SGDID:S000001278, Chr IX from 321452-321931, Verified ORF, "Protein of unknown function proposed to be involved in nuclear pore complex biogenesis and maintenance as well as protein folding; has similarity to the mammalian BAG-1 protein" |
| 2643 | YIL017C | VID28 SGDID:S000001279, Chr IX from 320963-318198, reverse complement, Verified ORF, "Protein involved in proteasome-dependent catabolite degradation of fructose-1,6-bisphosphatase (FBPase); localized to the nucleus and the cytoplasm" |
| 2644 | YIL018W | RPL2B SGDID:S000001280, Chr IX from 316766-316769,317170-317930, Verified ORF, "Protein component of the large (60S) ribosomal subunit, identical to Rpl2Ap and has similarity to E. coli L2 and rat L8 ribosomal proteins; expression is upregulated at low temperatures" |
| 2645 | YIL019W | FAF1 SGDID:S000001281, Chr IX from 315091-316131, Verified ORF, "Protein required for pre-rRNA processing and 40S ribosomal subunit assembly" |
| 2646 | YIL020C | HIS6 SGDID:S000001282, Chr IX from 314818-314033, reverse complement, Verified ORF, "Phosphoribosyl-5-amino-1-phosphoribosyl-4-imidazolecarboxiamide isomerase, catalyzes the fourth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts" |
| 2647 | YIL021W | RPB3 SGDID:S000001283, Chr IX from 312903-313859, Verified ORF, "RNA polymerase II third largest subunit B44, part of central core; similar to prokaryotic alpha subunit" |
| 2648 | YIL022W | TIM44 SGDID:S000001284, Chr IX from 311163-312458, Verified ORF, "Peripheral mitochondrial membrane protein involved in mitochondrial protein import, tethers essential chaperone Ssc1p to the translocon channel at the matrix side of the inner membrane" |
| 2649 | YIL023C | YKE4 SGDID:S000001285, Chr IX from 310424-309384, reverse complement, Verified ORF, "Zinc transporter; localizes to the ER; null mutant is sensitive to calcofluor white, leads to zinc accumulation in cytosol; ortholog of the mouse KE4 and member of the ZIP (ZRT, IRT-like Protein) family" |
| 2650 | YIL024C | YIL024C SGDID:S000001286, Chr IX from 309169-308600, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p" |
| 2651 | YIL026C | IRR1 SGDID:S000001288, Chr IX from 307927-304475, reverse complement, Verified ORF, "Subunit of the cohesin complex, which is required for sister chromatid cohesion during mitosis and meiosis and interacts with centromeres and chromosome arms, essential for viability" |
| 2652 | YIL027C | KRE27 SGDID:S000001289, Chr IX from 304102-303677, reverse complement, Verified ORF, "Protein of unknown function; null mutant shows K1 killer toxin resistance" |
| 2653 | YIL029C | YIL029C SGDID:S000001291, Chr IX from 301255-300827, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)" |
| 2654 | YIL030C | SSM4 SGDID:S000001292, Chr IX from 300008-296049, reverse complement, Verified ORF, "Ubiquitin-protein ligase of the ER/nuclear envelope, required for degradation of Alpha2p and other proteins containing a Deg1 degradation signal; ssm4 mutation suppresses mRNA instability caused by an rna14 mutation" |
| 2655 | YIL031W | ULP2 SGDID:S000001293, Chr IX from 292632-295736, Verified ORF, "Peptidase that deconjugates Smt3/SUMO-1 peptides from proteins, plays a role in chromosome cohesion at centromeric regions and recovery from checkpoint arrest induced by DNA damage or DNA replication defects; potential Cdc28p substrate" |
| 2656 | YIL033C | BCY1 SGDID:S000001295, Chr IX from 291668-290418, reverse complement, Verified ORF, "Regulatory subunit of the cyclic AMP-dependent protein kinase (PKA), a component of a signaling pathway that controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation" |
| 2657 | YIL034C | CAP2 SGDID:S000001296, Chr IX from 290088-289225, reverse complement, Verified ORF, "Beta subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches" |
| 2658 | YIL035C | CKA1 SGDID:S000001297, Chr IX from 288907-287789, reverse complement, Verified ORF, "Alpha catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA2, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases" |
| 2659 | YIL036W | CST6 SGDID:S000001298, Chr IX from 285665-287428, Verified ORF, "Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, activates transcription of genes involved in utilization of non-optimal carbon sources; involved in telomere maintenance" |
| 2660 | YIL037C | PRM2 SGDID:S000001299, Chr IX from 284998-283028, reverse complement, Verified ORF, "Pheromone-regulated protein, predicted to have 4 transmembrane segments and a coiled coil domain; regulated by Ste12p" |
| 2661 | YIL038C | NOT3 SGDID:S000001300, Chr IX from 282651-280141, reverse complement, Verified ORF, "Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation" |
| 2662 | YIL039W | TED1 SGDID:S000001301, Chr IX from 278425-279846, Uncharacterized ORF, "Conserved phosphoesterase domain-containing protein that acts together with Emp24p/Erv25p in cargo exit from the ER; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)" |
| 2663 | YIL040W | APQ12 SGDID:S000001302, Chr IX from 277722-278138, Verified ORF, "Protein involved in nucleocytoplasmic transport of mRNA" |
| 2664 | YIL041W | GVP36 SGDID:S000001303, Chr IX from 276524-277504, Verified ORF, "BAR domain-containing protein that localizes to both early and late Golgi vesicles; required for adaptation to varying nutrient concentrations, fluid-phase endocytosis, polarization of the actin cytoskeleton, and vacuole biogenesis" |
| 2665 | YIL042C | PKP1 SGDID:S000001304, Chr IX from 276291-275107, reverse complement, Verified ORF, "Mitochondrial protein kinase involved in negative regulation of pyruvate dehydrogenase complex activity by phosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinase Pkp2p and phosphatases Ptc5p and Ptc6p" |
| 2666 | YIL043C | CBR1 SGDID:S000001305, Chr IX from 274925-274071, reverse complement, Verified ORF, "Microsomal cytochrome b reductase, not essential for viability; also detected in mitochondria; mutation in conserved NADH binding domain of the human ortholog results in type I methemoglobinemia" |
| 2667 | YIL044C | AGE2 SGDID:S000001306, Chr IX from 273845-272949, reverse complement, Verified ORF, "ADP-ribosylation factor (ARF) GTPase activating protein (GAP) effector, involved in Trans-Golgi-Network (TGN) transport; contains C2C2H2 cysteine/histidine motif" |
| 2668 | YIL045W | PIG2 SGDID:S000001307, Chr IX from 271160-272776, Verified ORF, "Putative type-1 protein phosphatase targeting subunit that tethers Glc7p type-1 protein phosphatase to Gsy2p glycogen synthase" |
| 2669 | YIL046W | MET30 SGDID:S000001308, Chr IX from 268650-270572, Verified ORF, "F-box protein containing five copies of the WD40 motif, controls cell cycle function, sulfur metabolism, and methionine biosynthesis as part of the ubiquitin ligase complex; interacts with and regulates Met4p, localizes within the nucleus" |
| 2670 | YIL046W-A | YIL046W-A SGDID:S000028836, Chr IX from 268308-268472, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 2671 | YIL047C | SYG1 SGDID:S000001309, Chr IX from 267822-265114, reverse complement, Verified ORF, "Plasma membrane protein of unknown function; truncation and overexpression suppresses lethality of G-alpha protein deficiency" |
| 2672 | YIL048W | NEO1 SGDID:S000001310, Chr IX from 261436-264891, Verified ORF, "Putative aminophospholipid translocase (flippase) involved in endocytosis and vacuolar biogenesis; localizes to endosomes and the Golgi aparatus" |
| 2673 | YIL049W | DFG10 SGDID:S000001311, Chr IX from 260157-260918, Verified ORF, "Protein of unknown function, involved in filamentous growth" |
| 2674 | YIL050W | PCL7 SGDID:S000001312, Chr IX from 258912-259769, Verified ORF, "Pho85p cyclin of the Pho80p subfamily, forms a functional kinase complex with Pho85p which phosphorylates Mmr1p and is regulated by Pho81p; involved in glycogen metabolism, expression is cell-cycle regulated" |
| 2675 | YIL051C | MMF1 SGDID:S000001313, Chr IX from 258279-257842, reverse complement, Verified ORF, "Mitochondrial protein involved in maintenance of the mitochondrial genome" |
| 2676 | YIL052C | RPL34B SGDID:S000001314, Chr IX from 257061-257025,256552-256224, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl34Ap and has similarity to rat L34 ribosomal protein" |
| 2677 | YIL053W | RHR2 SGDID:S000001315, Chr IX from 255113-255865, Verified ORF, "Constitutively expressed isoform of DL-glycerol-3-phosphatase; involved in glycerol biosynthesis, induced in response to both anaerobic and, along with the Hor2p/Gpp2p isoform, osmotic stress" |
| 2678 | YIL055C | YIL055C SGDID:S000001317, Chr IX from 253923-252040, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 2679 | YIL056W | VHR1 SGDID:S000001318, Chr IX from 249989-251911, Verified ORF, "Transcriptional activator, required for the vitamin H-responsive element (VHRE) mediated induction of VHT1 (Vitamin H transporter) and BIO5 (biotin biosynthesis intermediate transporter) in response to low biotin concentrations" |
| 2680 | YIL057C | YIL057C SGDID:S000001319, Chr IX from 248393-247899, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; expression induced under carbon limitation and repressed under high glucose" |
| 2681 | YIL060W | YIL060W SGDID:S000001322, Chr IX from 246389-246823, Uncharacterized ORF, "Putative protein of unknown function; mutant accumulates less glycogen than does wild type; YIL060W is not an essential gene" |
| 2682 | YIL061C | SNP1 SGDID:S000001323, Chr IX from 245556-244654, reverse complement, Verified ORF, "Component of U1 snRNP required for mRNA splicing via spliceosome; may interact with poly(A) polymerase to regulate polyadenylation; homolog of human U1 70K protein" |
| 2683 | YIL062C | ARC15 SGDID:S000001324, Chr IX from 244459-243995, reverse complement, Verified ORF, "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches" |
| 2684 | YIL063C | YRB2 SGDID:S000001325, Chr IX from 243741-242758, reverse complement, Verified ORF, "Protein of unknown function involved in nuclear processes of the Ran-GTPase cycle; involved in nuclear protein export; contains Ran Binding Domain and FxFG repeats; interacts with Srm1p, GTP-Gsp1p, Rna1p and Crm1p; is not essential" |
| 2685 | YIL064W | YIL064W SGDID:S000001326, Chr IX from 241940-242713, Uncharacterized ORF, "Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family" |
| 2686 | YIL065C | FIS1 SGDID:S000001327, Chr IX from 241772-241305, reverse complement, Verified ORF, "Mitochondrial outer membrane protein involved in membrane fission, required for localization of Dnm1p and Mdv1p during mitochondrial division; mediates ethanol-induced apoptosis and ethanol-induced mitochondrial fragmentation" |
| 2687 | YIL066C | RNR3 SGDID:S000001328, Chr IX from 240705-238096, reverse complement, Verified ORF, "One of two large regulatory subunits of ribonucleotide-diphosphate reductase; the RNR complex catalyzes rate-limiting step in dNTP synthesis, regulated by DNA replication and DNA damage checkpoint pathways via localization of small subunits" |
| 2688 | YIL067C | YIL067C SGDID:S000001329, Chr IX from 237757-235721, reverse complement, Uncharacterized ORF, "Uncharacterized protein of unknown function" |
| 2689 | YIL068C | SEC6 SGDID:S000001330, Chr IX from 235471-233054, reverse complement, Verified ORF, "Essential 88kDa subunit of the exocyst complex, which mediates polarized targeting of secretory vesicles to active sites of exocytosis; dimeric form of Sec6p interacts with Sec9p in vitro and inhibits t-SNARE assembly" |
| 2690 | YIL069C | RPS24B SGDID:S000001331, Chr IX from 232366-232364,231954-231550, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; identical to Rps24Ap and has similarity to rat S24 ribosomal protein" |
| 2691 | YIL070C | MAM33 SGDID:S000001332, Chr IX from 231069-230269, reverse complement, Verified ORF, "Acidic protein of the mitochondrial matrix involved in oxidative phosphorylation; related to the human complement receptor gC1q-R" |
| 2692 | YIL071C | PCI8 SGDID:S000001333, Chr IX from 229991-228657, reverse complement, Verified ORF, "Possible shared subunit of Cop9 signalosome (CSN) and eIF3, binds eIF3b subunit Prt1p, has possible dual functions in transcriptional and translational control, contains a PCI (Proteasome-COP9 signalosome (CSN)-eIF3) domain" |
| 2693 | YIL072W | HOP1 SGDID:S000001334, Chr IX from 226599-228416, Verified ORF, "Meiosis-specific DNA binding protein that displays Red1p dependent localization to the unsynapsed axial-lateral elements of the synaptonemal complex; required for homologous chromosome synapsis and chiasma formation" |
| 2694 | YIL073C | SPO22 SGDID:S000001335, Chr IX from 225951-225897,225806-222934, reverse complement, Verified ORF, "Meiosis-specific protein essential for chromosome synapsis, involved in completion of nuclear divisions during meiosis; induced early in meiosis" |
| 2695 | YIL074C | SER33 SGDID:S000001336, Chr IX from 222487-221078, reverse complement, Verified ORF, "3-phosphoglycerate dehydrogenase, catalyzes the first step in serine and glycine biosynthesis; isozyme of Ser3p" |
| 2696 | YIL075C | RPN2 SGDID:S000001337, Chr IX from 220697-217860, reverse complement, Verified ORF, "Subunit of the 26S proteasome, substrate of the N-acetyltransferase Nat1p" |
| 2697 | YIL076W | SEC28 SGDID:S000001338, Chr IX from 216655-217545, Verified ORF, "Epsilon-COP subunit of the coatomer; regulates retrograde Golgi-to-ER protein traffic; stabilizes Cop1p, the alpha-COP and the coatomer complex; non-essential for cell growth" |
| 2698 | YIL077C | YIL077C SGDID:S000001339, Chr IX from 215950-214988, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)" |
| 2699 | YIL078W | THS1 SGDID:S000001340, Chr IX from 212496-214700, Verified ORF, "Threonyl-tRNA synthetase, essential cytoplasmic protein" |
| 2700 | YIL079C | AIR1 SGDID:S000001341, Chr IX from 212002-210920, reverse complement, Verified ORF, "RING finger protein that interacts with the arginine methyltransferase Hmt1p to regulate methylation of Npl3p, which modulates Npl3p function in mRNA processing and export; has similarity to Air2p" |
| 2701 | YIL082W-A | YIL082W-A SGDID:S000003537, Chr IX from 205632-206482,206484-210129, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 2702 | YIL083C | YIL083C SGDID:S000001345, Chr IX from 204650-203553, reverse complement, Uncharacterized ORF, "Putative phosphopantothenoylcysteine synthetase (PPCS) that catalyzes the second step in the biosynthesis of coenzyme A from pantothenate; conserved in bacteria, humans, and plants; essential for viability" |
| 2703 | YIL084C | SDS3 SGDID:S000001346, Chr IX from 203256-202273, reverse complement, Verified ORF, "Component of the Rpd3p/Sin3p deacetylase complex required for its structural integrity and catalytic activity, involved in transcriptional silencing and required for sporulation; cells defective in SDS3 display pleiotropic phenotypes" |
| 2704 | YIL085C | KTR7 SGDID:S000001347, Chr IX from 202040-200487, reverse complement, Verified ORF, "Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family" |
| 2705 | YIL087C | YIL087C SGDID:S000001349, Chr IX from 200116-199643, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; protein is detected in purified mitochondria in high-throughput studies; null mutant displays decreased mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media" |
| 2706 | YIL088C | AVT7 SGDID:S000001350, Chr IX from 199400-197928, reverse complement, Verified ORF, "Putative transporter, member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" |
| 2707 | YIL089W | YIL089W SGDID:S000001351, Chr IX from 195596-196213, Uncharacterized ORF, "Putative protein of unknown function" |
| 2708 | YIL090W | ICE2 SGDID:S000001352, Chr IX from 193592-195067, Verified ORF, "Integral ER membrane protein with type-III transmembrane domains; mutations cause defects in cortical ER morphology in both the mother and daughter cells" |
| 2709 | YIL091C | YIL091C SGDID:S000001353, Chr IX from 193192-191027, reverse complement, Uncharacterized ORF, "Protein required for cell viability" |
| 2710 | YIL092W | YIL092W SGDID:S000001354, Chr IX from 189063-190964, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus" |
| 2711 | YIL093C | RSM25 SGDID:S000001355, Chr IX from 188781-187987, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 2712 | YIL094C | LYS12 SGDID:S000001356, Chr IX from 187629-186514, reverse complement, Verified ORF, "Homo-isocitrate dehydrogenase, an NAD-linked mitochondrial enzyme required for the fourth step in the biosynthesis of lysine, in which homo-isocitrate is oxidatively decarboxylated to alpha-ketoadipate" |
| 2713 | YIL095W | PRK1 SGDID:S000001357, Chr IX from 183934-186366, Verified ORF, "Protein serine/threonine kinase; regulates the organization and function of the actin cytoskeleton through the phosphorylation of the Pan1p-Sla1p-End3p protein complex" |
| 2714 | YIL096C | YIL096C SGDID:S000001358, Chr IX from 183124-182114, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; associates with precursors of the 60S ribosomal subunit" |
| 2715 | YIL097W | FYV10 SGDID:S000001359, Chr IX from 180424-181974, Verified ORF, "Protein of unknown function, required for survival upon exposure to K1 killer toxin; involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains CTLH domain" |
| 2716 | YIL098C | FMC1 SGDID:S000001360, Chr IX from 180236-179769, reverse complement, Verified ORF, "Mitochondrial matrix protein, required for assembly or stability at high temperature of the F1 sector of mitochondrial F1F0 ATP synthase; null mutant temperature sensitive growth on glycerol is suppressed by multicopy expression of Odc1p" |
| 2717 | YIL099W | SGA1 SGDID:S000001361, Chr IX from 178001-179650, Verified ORF, "Intracellular sporulation-specific glucoamylase involved in glycogen degradation; induced during starvation of a/a diploids late in sporulation, but dispensable for sporulation" |
| 2718 | YIL101C | XBP1 SGDID:S000001363, Chr IX from 177247-175304, reverse complement, Verified ORF, "Transcriptional repressor that binds to promoter sequences of the cyclin genes, CYS3, and SMF2; expression is induced by stress or starvation during mitosis, and late in meiosis; member of the Swi4p/Mbp1p family; potential Cdc28p substrate" |
| 2719 | YIL102C | YIL102C SGDID:S000001364, Chr IX from 174884-174579, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 2720 | YIL102C-A | YIL102C-A SGDID:S000113587, Chr IX from 173589-173362, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, identified based on comparisons of the genome sequences of six Saccharomyces species" |
| 2721 | YIL103W | DPH1 SGDID:S000001365, Chr IX from 171748-173025, Verified ORF, "Protein required, along with Dph2p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph2p and Kti11p" |
| 2722 | YIL104C | SHQ1 SGDID:S000001366, Chr IX from 171502-169979, reverse complement, Verified ORF, "Essential nuclear protein, required for accumulation of box H/ACA snoRNAs and for rRNA processing; interacts with Naf1p" |
| 2723 | YIL105C | SLM1 SGDID:S000001367, Chr IX from 169638-167578, reverse complement, Verified ORF, "Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm2p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; subunit of and phosphorylated by the TORC2 complex" |
| 2724 | YIL106W | MOB1 SGDID:S000001368, Chr IX from 166412-166431,166517-167441, Verified ORF, "Component of the mitotic exit network; associates with and is required for the activation and Cdc15p-dependent phosphorylation of the Dbf2p kinase; required for cytokinesis and cell separation; component of the CCR4 transcriptional complex" |
| 2725 | YIL107C | PFK26 SGDID:S000001369, Chr IX from 165758-163275, reverse complement, Verified ORF, "6-phosphofructo-2-kinase, inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate, has negligible fructose-2,6-bisphosphatase activity, transcriptional regulation involves protein kinase A" |
| 2726 | YIL108W | YIL108W SGDID:S000001370, Chr IX from 160884-162974, Uncharacterized ORF, "Putative metalloprotease" |
| 2727 | YIL109C | SEC24 SGDID:S000001371, Chr IX from 160162-157382, reverse complement, Verified ORF, "Component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat; involved in ER to Golgi transport, cargo selection and autophagy; required for the binding of the Sec13 complex to ER membranes; homologous to Lst1p and Lss1p" |
| 2728 | YIL110W | YIL110W SGDID:S000001372, Chr IX from 156042-157175, Uncharacterized ORF, "Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; deletion mutant exhibits a weak vacuolar protein sorting defect, enhanced resistance to caspofungin, and is synthetically lethal with MEN mutants" |
| 2729 | YIL111W | COX5B SGDID:S000001373, Chr IX from 155219-155219,155308-155762, Verified ORF, "Subunit Vb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during anaerobic growth while its isoform Va (Cox5Ap) is expressed during aerobic growth" |
| 2730 | YIL112W | HOS4 SGDID:S000001374, Chr IX from 151592-154843, Verified ORF, "Subunit of the Set3 complex, which is a meiotic-specific repressor of sporulation specific genes that contains deacetylase activity; potential Cdc28p substrate" |
| 2731 | YIL113W | SDP1 SGDID:S000001375, Chr IX from 150556-151185, Verified ORF, "Stress-inducible dual-specificity MAP kinase phosphatase, negatively regulates Slt2p MAP kinase by direct dephosphorylation, diffuse localization under normal conditions shifts to punctate localization after heat shock" |
| 2732 | YIL114C | POR2 SGDID:S000001376, Chr IX from 149985-149140, reverse complement, Verified ORF, "Putative mitochondrial porin (voltage-dependent anion channel), related to Por1p but not required for mitochondrial membrane permeability or mitochondrial osmotic stability" |
| 2733 | YIL115C | NUP159 SGDID:S000001377, Chr IX from 148706-144324, reverse complement, Verified ORF, "Nucleoporin, subunit of the nuclear pore complex that is found exclusively on the cytoplasmic side, forms a subcomplex with Nup82p and Nsp1p, required for mRNA export" |
| 2734 | YIL116W | HIS5 SGDID:S000001378, Chr IX from 142925-144082, Verified ORF, "Histidinol-phosphate aminotransferase, catalyzes the seventh step in histidine biosynthesis; responsive to general control of amino acid biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts" |
| 2735 | YIL117C | PRM5 SGDID:S000001379, Chr IX from 141566-140610, reverse complement, Verified ORF, "Pheromone-regulated protein, predicted to have 1 transmembrane segment; induced during cell integrity signaling" |
| 2736 | YIL118W | RHO3 SGDID:S000001380, Chr IX from 139749-140444, Verified ORF, "Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins involved in the establishment of cell polarity; GTPase activity positively regulated by the GTPase activating protein (GAP) Rgd1p" |
| 2737 | YIL119C | RPI1 SGDID:S000001381, Chr IX from 137874-136651, reverse complement, Verified ORF, "Putative transcriptional regulator; overexpression suppresses the heat shock sensitivity of wild-type RAS2 overexpression and also suppresses the cell lysis defect of an mpk1 mutation" |
| 2738 | YIL120W | QDR1 SGDID:S000001382, Chr IX from 134414-136105, Verified ORF, "Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, ketoconazole, fluconazole, and barban" |
| 2739 | YIL121W | QDR2 SGDID:S000001383, Chr IX from 132241-133869, Verified ORF, "Multidrug transporter of the major facilitator superfamily, required for resistance to quinidine, barban, cisplatin, and bleomycin; may have a role in potassium uptake" |
| 2740 | YIL122W | POG1 SGDID:S000001384, Chr IX from 130607-131662, Verified ORF, "Putative transcriptional activator that promotes recovery from pheromone induced arrest; inhibits both alpha-factor induced G1 arrest and repression of CLN1 and CLN2 via SCB/MCB promoter elements; potential Cdc28p substrate; SBF regulated" |
| 2741 | YIL123W | SIM1 SGDID:S000001385, Chr IX from 128151-129578, Verified ORF, "Protein of the SUN family (Sim1p, Uth1p, Nca3p, Sun4p) that may participate in DNA replication, promoter contains SCB regulation box at -300 bp indicating that expression may be cell cycle-regulated" |
| 2742 | YIL124W | AYR1 SGDID:S000001386, Chr IX from 126204-127097, Verified ORF, "NADPH-dependent 1-acyl dihydroxyacetone phosphate reductase found in lipid particles, ER, and mitochondrial outer membrane; involved in phosphatidic acid biosynthesis; required for spore germination; capable of metabolizing steroid hormones" |
| 2743 | YIL125W | KGD1 SGDID:S000001387, Chr IX from 122689-125733, Verified ORF, "Component of the mitochondrial alpha-ketoglutarate dehydrogenase complex, which catalyzes a key step in the tricarboxylic acid (TCA) cycle, the oxidative decarboxylation of alpha-ketoglutarate to form succinyl-CoA" |
| 2744 | YIL126W | STH1 SGDID:S000001388, Chr IX from 117992-122071, Verified ORF, "ATPase component of the RSC chromatin remodeling complex; required for expression of early meiotic genes; essential helicase-related protein homologous to Snf2p" |
| 2745 | YIL127C | YIL127C SGDID:S000001389, Chr IX from 117644-117024, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus" |
| 2746 | YIL128W | MET18 SGDID:S000001390, Chr IX from 113806-116904, Verified ORF, "DNA repair and TFIIH regulator, required for both nucleotide excision repair (NER) and RNA polymerase II (RNAP II) transcription; involved in telomere maintenance" |
| 2747 | YIL129C | TAO3 SGDID:S000001391, Chr IX from 113237-106107, reverse complement, Verified ORF, "Protein involved in cell morphogenesis and proliferation, associated with protein kinase Cbk1p; mutants activate OCH1 transcription" |
| 2748 | YIL130W | ASG1 SGDID:S000001392, Chr IX from 102782-105676, Verified ORF, "Proposed transcriptional activator, member of the Gal4p family of zinc cluster proteins" |
| 2749 | YIL131C | FKH1 SGDID:S000001393, Chr IX from 102235-100781, reverse complement, Verified ORF, "Forkhead family transcription factor with a minor role in the expression of G2/M phase genes; negatively regulates transcriptional elongation; positive role in chromatin silencing at HML and HMR; regulates donor preference during switching" |
| 2750 | YIL132C | CSM2 SGDID:S000001394, Chr IX from 100501-99860, reverse complement, Verified ORF, "Protein required for accurate chromosome segregation during meiosis" |
| 2751 | YIL133C | RPL16A SGDID:S000001395, Chr IX from 99416-99386,99095-98527, reverse complement, Verified ORF, "N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Bp, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p" |
| 2752 | YIL134C-A | YIL134C-A SGDID:S000028556, Chr IX from 96725-96522, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, identified by fungal homology and RT-PCR" |
| 2753 | YIL134W | FLX1 SGDID:S000001396, Chr IX from 97395-98330, Verified ORF, "Protein required for transport of flavin adenine dinucleotide (FAD), a synthesis product of riboflavin, across the mitochondrial membrane" |
| 2754 | YIL135C | VHS2 SGDID:S000001397, Chr IX from 96375-95065, reverse complement, Verified ORF, "Cytoplasmic protein of unknown function; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; similar to Mlf3p" |
| 2755 | YIL136W | OM45 SGDID:S000001398, Chr IX from 93619-94800, Verified ORF, "Protein of unknown function, major constituent of the mitochondrial outer membrane; located on the outer (cytosolic) face of the outer membrane" |
| 2756 | YIL137C | TMA108 SGDID:S000001399, Chr IX from 92788-89948, reverse complement, Verified ORF, "Protein that associates with ribosomes; putative metalloprotease" |
| 2757 | YIL138C | TPM2 SGDID:S000001400, Chr IX from 89715-89230, reverse complement, Verified ORF, "Minor isoform of tropomyosin, binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; appears to have distinct and also overlapping functions with Tpm1p" |
| 2758 | YIL139C | REV7 SGDID:S000001401, Chr IX from 88716-87979, reverse complement, Verified ORF, "Processivity subunit of DNA polymerase zeta, which is involved in DNA repair and translesion synthesis; required for mutagenesis induced by DNA damage" |
| 2759 | YIL140W | AXL2 SGDID:S000001402, Chr IX from 85366-87837, Verified ORF, "Integral plasma membrane protein required for axial budding in haploid cells, localizes to the incipient bud site and bud neck; glycosylated by Pmt4p; potential Cdc28p substrate" |
| 2760 | YIL142W | CCT2 SGDID:S000001404, Chr IX from 83302-84885, Verified ORF, "Subunit beta of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" |
| 2761 | YIL143C | SSL2 SGDID:S000001405, Chr IX from 83041-80510, reverse complement, Verified ORF, "Component of the holoenzyme form of RNA polymerase transcription factor TFIIH, has DNA-dependent ATPase/helicase activity and is required, with Rad3p, for unwinding promoter DNA; involved in DNA repair; homolog of human ERCC3" |
| 2762 | YIL144W | TID3 SGDID:S000001406, Chr IX from 78074-80149, Verified ORF, "Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); conserved coiled-coil protein involved in chromosome segregation, spindle checkpoint activity, kinetochore assembly and clustering" |
| 2763 | YIL145C | PAN6 SGDID:S000001407, Chr IX from 77283-76354, reverse complement, Verified ORF, "Pantothenate synthase, also known as pantoate-beta-alanine ligase, required for pantothenic acid biosynthesis, deletion causes pantothenic acid auxotrophy, homologous to E. coli panC" |
| 2764 | YIL146C | ECM37 SGDID:S000001408, Chr IX from 75773-74184, reverse complement, Verified ORF, "Non-essential protein of unknown function" |
| 2765 | YIL147C | SLN1 SGDID:S000001409, Chr IX from 73453-69791, reverse complement, Verified ORF, "Histidine kinase osmosensor that regulates a MAP kinase cascade; transmembrane protein with an intracellular kinase domain that signals to Ypd1p and Ssk1p, thereby forming a phosphorelay system similar to bacterial two-component regulators" |
| 2766 | YIL148W | RPL40A SGDID:S000001410, Chr IX from 68708-68715,69150-69528, Verified ORF, "Fusion protein, identical to Rpl40Bp, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes" |
| 2767 | YIL149C | MLP2 SGDID:S000001411, Chr IX from 68067-63028, reverse complement, Verified ORF, "Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved in the Tel1p pathway that controls telomere length" |
| 2768 | YIL150C | MCM10 SGDID:S000001412, Chr IX from 62728-61013, reverse complement, Verified ORF, "Essential chromatin-associated protein involved in the initiation of DNA replication; required for the association of the MCM2-7 complex with replication origins" |
| 2769 | YIL151C | YIL151C SGDID:S000001413, Chr IX from 60694-57338, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, predicted to contain a PINc (PilT N terminus) domain" |
| 2770 | YIL152W | YIL152W SGDID:S000001414, Chr IX from 56545-57252, Uncharacterized ORF, "Putative protein of unknown function" |
| 2771 | YIL153W | RRD1 SGDID:S000001415, Chr IX from 55198-56379, Verified ORF, "Peptidyl-prolyl cis/trans-isomerase, activator of the phosphotyrosyl phosphatase activity of PP2A; involved in G1 phase progression, microtubule dynamics, bud morphogenesis and DNA repair; subunit of the Tap42p-Sit4p-Rrd1p complex" |
| 2772 | YIL154C | IMP2' SGDID:S000001416, Chr IX from 55021-53981, reverse complement, Verified ORF, "Transcriptional activator involved in maintenance of ion homeostasis and protection against DNA damage caused by bleomycin and other oxidants, contains a C-terminal leucine-rich repeat" |
| 2773 | YIL155C | GUT2 SGDID:S000001417, Chr IX from 53708-51759, reverse complement, Verified ORF, "Mitochondrial glycerol-3-phosphate dehydrogenase; expression is repressed by both glucose and cAMP and derepressed by non-fermentable carbon sources in a Snf1p, Rsf1p, Hap2/3/4/5 complex dependent manner" |
| 2774 | YIL156W | UBP7 SGDID:S000001418, Chr IX from 48091-51306, Verified ORF, "Ubiquitin-specific protease that cleaves ubiquitin-protein fusions" |
| 2775 | YIL156W-B | YIL156W-B SGDID:S000028511, Chr IX from 47690-47698,47761-47973, Uncharacterized ORF, "Putative protein of unknown function, originally identified based on homology to Ashbya gossypii and other related yeasts" |
| 2776 | YIL157C | COA1 SGDID:S000001419, Chr IX from 47542-46949, reverse complement, Verified ORF, "Mitochondrial inner membrane protein required for assembly of the cytochrome c oxidase complex (complex IV); interacts with complex IV assembly factor Shy1p during the early stages of assembly" |
| 2777 | YIL158W | YIL158W SGDID:S000001420, Chr IX from 46201-46815, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; null mutant displays increased frequency of mitochondrial genome loss (petite formation)" |
| 2778 | YIL159W | BNR1 SGDID:S000001421, Chr IX from 41825-45952, Verified ORF, "Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNI1" |
| 2779 | YIL160C | POT1 SGDID:S000001422, Chr IX from 41444-40191, reverse complement, Verified ORF, "3-ketoacyl-CoA thiolase with broad chain length specificity, cleaves 3-ketoacyl-CoA into acyl-CoA and acetyl-CoA during beta-oxidation of fatty acids" |
| 2780 | YIL161W | YIL161W SGDID:S000001423, Chr IX from 39433-40140, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; mRNA is enriched in Scp160p-associated mRNPs; YIL161W is a non-essential gene" |
| 2781 | YIL162W | SUC2 SGDID:S000001424, Chr IX from 37385-38983, Verified ORF, "Invertase, sucrose hydrolyzing enzyme; a secreted, glycosylated form is regulated by glucose repression, and an intracellular, nonglycosylated enzyme is produced constitutively" |
| 2782 | YIL164C | NIT1 SGDID:S000001426, Chr IX from 34686-34087, reverse complement, Verified ORF, "Nitrilase, member of the nitrilase branch of the nitrilase superfamily; in closely related species and other S. cerevisiae strain backgrounds YIL164C and adjacent ORF, YIL165C, likely constitute a single ORF encoding a nitrilase gene" |
| 2783 | YIL165C | YIL165C SGDID:S000001427, Chr IX from 34077-33718, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; in closely related species and other S. cerevisiae strain backgrounds YIL165C and adjacent ORF, YIL164C, likely constitute a single ORF encoding a nitrilase gene" |
| 2784 | YIL166C | YIL166C SGDID:S000001428, Chr IX from 32566-30938, reverse complement, Uncharacterized ORF, "Putative protein with similarity to the allantoate permease (Dal5p) subfamily of the major facilitator superfamily; mRNA expression is elevated by sulfur limitation; YIL166C is a non-essential gene" |
| 2785 | YIL169C | YIL169C SGDID:S000001431, Chr IX from 26106-23119, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; serine/threonine rich and highly similar to YOL155C, a putative glucan alpha-1,4-glucosidase; transcript is induced in both high and low pH environments; YIL169C is a non-essential gene" |
| 2786 | YIL172C | YIL172C SGDID:S000001434, Chr IX from 18553-16784, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with similarity to glucosidases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 2787 | YIL173W | VTH1 SGDID:S000001435, Chr IX from 11492-16141, Verified ORF, "Putative membrane glycoprotein with strong similarity to Vth2p and Pep1p/Vps10p, may be involved in vacuolar protein sorting" |
| 2788 | YIL176C | YIL176C SGDID:S000001438, Chr IX from 9155-8793, reverse complement, Uncharacterized ORF, "Hypothetical protein" |
| 2789 | YIL177C | YIL177C SGDID:S000001439, Chr IX from 6147-4987,4598-483, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; similarity to DNA helicases that are encoded within subtelomeric Y' elements and induced in telomerase deficient survivors" |
| 2790 | YIR001C | SGN1 SGDID:S000001440, Chr IX from 356892-356140, reverse complement, Verified ORF, "Cytoplasmic RNA-binding protein, contains an RNA recognition motif (RRM); may have a role in mRNA translation, as suggested by genetic interactions with genes encoding proteins involved in translational initiation" |
| 2791 | YIR002C | MPH1 SGDID:S000001441, Chr IX from 360393-357412, reverse complement, Verified ORF, "Member of the DEAH family of helicases, functions in an error-free DNA damage bypass pathway that involves homologous recombination, mutations confer a mutator phenotype" |
| 2792 | YIR003W | YIR003W SGDID:S000001442, Chr IX from 360882-362921, Verified ORF, "Protein of unknown function; may interact with ribosomes; GFP-fusion protein colocalizes with Sac1p to the actin cytoskeleton; null mutant displays increased frequency of mitochondrial genome loss (petite formation)" |
| 2793 | YIR004W | DJP1 SGDID:S000001443, Chr IX from 363218-364516, Verified ORF, "Cytosolic J-domain-containing protein, required for peroxisomal protein import and involved in peroxisome assembly, homologous to E. coli DnaJ" |
| 2794 | YIR005W | IST3 SGDID:S000001444, Chr IX from 364886-365332, Verified ORF, "Component of the U2 snRNP, required for the first catalytic step of splicing and for spliceosomal assembly; interacts with Rds3p and is required for Mer1p-activated splicing" |
| 2795 | YIR006C | PAN1 SGDID:S000001445, Chr IX from 369905-365463, reverse complement, Verified ORF, "Part of actin cytoskeleton-regulatory complex Pan1p-Sla1p-End3p, associates with actin patches on the cell cortex; promotes protein-protein interactions essential for endocytosis; previously thought to be a subunit of poly(A) ribonuclease" |
| 2796 | YIR007W | YIR007W SGDID:S000001446, Chr IX from 370701-372995, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YIR007W is a non-essential gene" |
| 2797 | YIR008C | PRI1 SGDID:S000001447, Chr IX from 374303-373074, reverse complement, Verified ORF, "Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair" |
| 2798 | YIR009W | MSL1 SGDID:S000001448, Chr IX from 374522-374857, Verified ORF, "U2B component of U2 snRNP, involved in splicing, binds the U2 snRNA stem-loop IV in vitro; does not contain the conserved C-terminal RNA binding domain found in other family members" |
| 2799 | YIR010W | DSN1 SGDID:S000001449, Chr IX from 375428-377158, Verified ORF, "Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; important for chromosome segregation" |
| 2800 | YIR011C | STS1 SGDID:S000001450, Chr IX from 378243-377284, reverse complement, Verified ORF, "Protein that interacts with the karyopherin Srp1p; may have a role with Srp1p in ubiquitin-mediated protein degradation" |
| 2801 | YIR012W | SQT1 SGDID:S000001451, Chr IX from 378483-379778, Verified ORF, "Essential protein involved in a late step of 60S ribosomal subunit assembly or modification; contains multiple WD repeats; interacts with Qsr1p in a two-hybrid assay" |
| 2802 | YIR013C | GAT4 SGDID:S000001452, Chr IX from 380381-380016, reverse complement, Verified ORF, "Protein containing GATA family zinc finger motifs" |
| 2803 | YIR014W | YIR014W SGDID:S000001453, Chr IX from 381083-381811, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p; YIR014W is a non-essential gene" |
| 2804 | YIR015W | RPR2 SGDID:S000001454, Chr IX from 381945-382379, Verified ORF, "Subunit of nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; not shared between RNase MRP and RNase P, in contrast to all other RNase P protein subunits" |
| 2805 | YIR016W | YIR016W SGDID:S000001455, Chr IX from 382625-383422, Uncharacterized ORF, "Putative protein of unknown function; expression directly regulated by the metabolic and meiotic transcriptional regulator Ume6p; YIR016W is a non-essential gene" |
| 2806 | YIR017C | MET28 SGDID:S000001456, Chr IX from 384116-383553, reverse complement, Verified ORF, "Transcriptional activator in the Cbf1p-Met4p-Met28p complex, participates in the regulation of sulfur metabolism" |
| 2807 | YIR018C-A | YIR018C-A SGDID:S000028837, Chr IX from 385698-385561, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 2808 | YIR018W | YAP5 SGDID:S000001457, Chr IX from 384606-385343, Verified ORF, "Basic leucine zipper (bZIP) transcription factor" |
| 2809 | YIR019C | MUC1 SGDID:S000001458, Chr IX from 393672-389569, reverse complement, Verified ORF, "GPI-anchored cell surface glycoprotein (flocculin) required for pseudohyphal formation, invasive growth, flocculation, and biofilms; transcriptionally regulated by the MAPK pathway (via Ste12p and Tec1p) and the cAMP pathway (via Flo8p)" |
| 2810 | YIR021W | MRS1 SGDID:S000001460, Chr IX from 397291-398382, Verified ORF, "Protein required for the splicing of two mitochondrial group I introns (BI3 in COB and AI5beta in COX1); forms a splicing complex, containing four subunits of Mrs1p and two subunits of the BI3-encoded maturase, that binds to the BI3 RNA" |
| 2811 | YIR021W-A | YIR021W-A SGDID:S000028838, Chr IX from 398511-398723, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 2812 | YIR022W | SEC11 SGDID:S000001461, Chr IX from 398730-399233, Verified ORF, "18kDa catalytic subunit of the Signal Peptidase Complex (SPC; Spc1p, Spc2p, Spc3p, and Sec11p) which cleaves the signal sequence of proteins targeted to the endoplasmic reticulum" |
| 2813 | YIR023W | DAL81 SGDID:S000001462, Chr IX from 399774-402686, Verified ORF, "Positive regulator of genes in multiple nitrogen degradation pathways; contains DNA binding domain but does not appear to bind the dodecanucleotide sequence present in the promoter region of many genes involved in allantoin catabolism" |
| 2814 | YIR024C | YIR024C SGDID:S000001463, Chr IX from 403488-402838, reverse complement, Verified ORF, "Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; interacts with Arh1p, a mitochondrial oxidoreductase; deletion mutant has a respiratory growth defect" |
| 2815 | YIR025W | MND2 SGDID:S000001464, Chr IX from 403656-404762, Verified ORF, "Subunit of the anaphase-promoting complex (APC); needed for meiotic nuclear division" |
| 2816 | YIR026C | YVH1 SGDID:S000001465, Chr IX from 405964-404870, reverse complement, Verified ORF, "Protein phosphatase involved in vegetative growth at low temperatures, sporulation, and glycogen accumulation; transcription induced by low temperature and nitrogen starvation; member of the dual-specificity family of protein phosphatases" |
| 2817 | YIR027C | DAL1 SGDID:S000001466, Chr IX from 407639-406257, reverse complement, Verified ORF, "Allantoinase, converts allantoin to allantoate in the first step of allantoin degradation; expression sensitive to nitrogen catabolite repression" |
| 2818 | YIR028W | DAL4 SGDID:S000001467, Chr IX from 408465-410372, Verified ORF, "Allantoin permease; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation" |
| 2819 | YIR029W | DAL2 SGDID:S000001468, Chr IX from 410804-411835, Verified ORF, "Allantoicase, converts allantoate to urea and ureidoglycolate in the second step of allantoin degradation; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation" |
| 2820 | YIR030C | DCG1 SGDID:S000001469, Chr IX from 412767-412033, reverse complement, Verified ORF, "Protein of unknown function, expression is sensitive to nitrogen catabolite repression and regulated by Dal80p; contains transmembrane domain" |
| 2821 | YIR031C | DAL7 SGDID:S000001470, Chr IX from 414676-413012, reverse complement, Verified ORF, "Malate synthase, role in allantoin degradation unknown; expression sensitive to nitrogen catabolite repression and induced by allophanate, an intermediate in allantoin degradation" |
| 2822 | YIR032C | DAL3 SGDID:S000001471, Chr IX from 415614-415027, reverse complement, Verified ORF, "Ureidoglycolate hydrolase, converts ureidoglycolate to glyoxylate and urea in the third step of allantoin degradation; expression sensitive to nitrogen catabolite repression" |
| 2823 | YIR033W | MGA2 SGDID:S000001472, Chr IX from 416121-419462, Verified ORF, "ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Spt23p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting" |
| 2824 | YIR034C | LYS1 SGDID:S000001473, Chr IX from 420733-419612, reverse complement, Verified ORF, "Saccharopine dehydrogenase (NAD+, L-lysine-forming), catalyzes the conversion of saccharopine to L-lysine, which is the final step in the lysine biosynthesis pathway" |
| 2825 | YIR035C | YIR035C SGDID:S000001474, Chr IX from 421787-421023, reverse complement, Uncharacterized ORF, "Putative cytoplasmic protein of unknown function" |
| 2826 | YIR036C | IRC24 SGDID:S000001475, Chr IX from 422862-422071, reverse complement, Uncharacterized ORF, "Putative benzil reductase;(GFP)-fusion protein localizes to the cytoplasm and is induced by the DNA-damaging agent MMS; sequence similarity with short-chain dehydrogenase/reductases; null mutant has increased spontaneous Rad52p foci" |
| 2827 | YIR037W | HYR1 SGDID:S000001476, Chr IX from 423125-423616, Verified ORF, "Thiol peroxidase that functions as a hydroperoxide receptor to sense intracellular hydroperoxide levels and transduce a redox signal to the Yap1p transcription factor" |
| 2828 | YIR038C | GTT1 SGDID:S000001477, Chr IX from 424510-423806, reverse complement, Verified ORF, "ER associated glutathione S-transferase capable of homodimerization; expression induced during the diauxic shift and throughout stationary phase; functional overlap with Gtt2p, Grx1p, and Grx2p" |
| 2829 | YIR039C | YPS6 SGDID:S000001478, Chr IX from 432107-430494, reverse complement, Verified ORF, "Putative GPI-anchored aspartic protease" |
| 2830 | YIR041W | PAU15 SGDID:S000001480, Chr IX from 433925-434299, Uncharacterized ORF, "Hypothetical protein" |
| 2831 | YIR042C | YIR042C SGDID:S000001481, Chr IX from 435980-435270, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YIR042C is a non-essential gene" |
| 2832 | YJL001W | PRE3 SGDID:S000003538, Chr X from 435157-435221,435338-435920, Verified ORF, "Beta 1 subunit of the 20S proteasome, responsible for cleavage after acidic residues in peptides" |
| 2833 | YJL002C | OST1 SGDID:S000003539, Chr X from 434645-433215, reverse complement, Verified ORF, "Alpha subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins" |
| 2834 | YJL003W | COX16 SGDID:S000003540, Chr X from 432638-432994, Verified ORF, "Mitochondrial inner membrane protein, required for assembly of cytochrome c oxidase" |
| 2835 | YJL004C | SYS1 SGDID:S000003541, Chr X from 432194-431583, reverse complement, Verified ORF, "Integral membrane protein of the Golgi required for targeting of the Arf-like GTPase Arl3p to the Golgi; multicopy suppressor of ypt6 null mutation" |
| 2836 | YJL005W | CYR1 SGDID:S000003542, Chr X from 425151-431231, Verified ORF, "Adenylate cyclase, required for cAMP production and cAMP-dependent protein kinase signaling; the cAMP pathway controls a variety of cellular processes, including metabolism, cell cycle, stress response, stationary phase, and sporulation" |
| 2837 | YJL006C | CTK2 SGDID:S000003543, Chr X from 424103-423132, reverse complement, Verified ORF, "Beta subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing; has similarity to cyclins" |
| 2838 | YJL008C | CCT8 SGDID:S000003545, Chr X from 421657-419951, reverse complement, Verified ORF, "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" |
| 2839 | YJL010C | NOP9 SGDID:S000003547, Chr X from 419556-417556, reverse complement, Verified ORF, "Essential component of pre-40S ribosomes that is required for early cleavages of 35S pre-rRNA and hence formation of 18S rRNA; binds RNA in vitro and contains multiple pumilio-like repeats" |
| 2840 | YJL011C | RPC17 SGDID:S000003548, Chr X from 414764-414279, reverse complement, Verified ORF, "RNA polymerase III subunit C17; physically interacts with C31, C11, and TFIIIB70; may be involved in the recruitment of pol III by the preinitiation complex" |
| 2841 | YJL012C | VTC4 SGDID:S000003549, Chr X from 413393-411228, reverse complement, Verified ORF, "Vacuolar membrane protein involved in vacuolar polyphosphate accumulation; functions as a regulator of vacuolar H+-ATPase activity and vacuolar transporter chaperones; involved in non-autophagic vacuolar fusion" |
| 2842 | YJL013C | MAD3 SGDID:S000003550, Chr X from 411034-409487, reverse complement, Verified ORF, "Subunit of the spindle-assembly checkpoint complex, which delays anaphase onset in cells with defects in mitotic spindle assembly; pseudosubstrate inhibitor of APC(Cdc20), the anaphase promoting complex involved in securin (Pds1p) turnover" |
| 2843 | YJL014W | CCT3 SGDID:S000003551, Chr X from 407552-409156, Verified ORF, "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" |
| 2844 | YJL016W | YJL016W SGDID:S000003553, Chr X from 405583-407268, Uncharacterized ORF, "Putative protein of unknown function; GFP-fusion protein localizes to the cytoplasm; conserved in closely related Saccharomyces species" |
| 2845 | YJL019W | MPS3 SGDID:S000003556, Chr X from 402892-404940, Verified ORF, "Essential integral membrane protein required for spindle pole body duplication and for nuclear fusion, localizes to the spindle pole body half bridge, interacts with DnaJ-like chaperone Jem1p and with centrin homolog Cdc31p" |
| 2846 | YJL020C | BBC1 SGDID:S000003557, Chr X from 402405-398932, reverse complement, Verified ORF, "Protein possibly involved in assembly of actin patches; interacts with an actin assembly factor Las17p and with the SH3 domains of Type I myosins Myo3p and Myo5p; localized predominantly to cortical actin patches" |
| 2847 | YJL023C | PET130 SGDID:S000003560, Chr X from 398393-397350, reverse complement, Verified ORF, "Protein required for respiratory growth; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2848 | YJL024C | APS3 SGDID:S000003561, Chr X from 396587-396566,396488-395926, reverse complement, Verified ORF, "Small subunit of the clathrin-associated adaptor complex AP-3, which is involved in vacuolar protein sorting; related to the sigma subunit of the mammalian clathrin AP-3 complex; suppressor of loss of casein kinase 1 function" |
| 2849 | YJL025W | RRN7 SGDID:S000003562, Chr X from 393962-395506, Verified ORF, "Protein involved in the transcription of 35S rRNA genes by RNA polymerase I; component of the core factor (CF) complex also composed of Rrn11p, Rrn6p and TATA-binding protein" |
| 2850 | YJL026W | RNR2 SGDID:S000003563, Chr X from 392399-393598, Verified ORF, "Ribonucleotide-diphosphate reductase (RNR), small subunit; the RNR complex catalyzes the rate-limiting step in dNTP synthesis and is regulated by DNA replication and DNA damage checkpoint pathways via localization of the small subunits" |
| 2851 | YJL027C | YJL027C SGDID:S000003564, Chr X from 392244-391828, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 2852 | YJL028W | YJL028W SGDID:S000003565, Chr X from 391306-391641, Verified ORF, "Protein of unknown function; may interact with ribosomes, based on co-purification experiments" |
| 2853 | YJL029C | VPS53 SGDID:S000003566, Chr X from 390848-388380, reverse complement, Verified ORF, "Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; required for vacuolar protein sorting" |
| 2854 | YJL030W | MAD2 SGDID:S000003567, Chr X from 387652-388242, Verified ORF, "Component of the spindle-assembly checkpoint complex, which delays the onset of anaphase in cells with defects in mitotic spindle assembly; forms a complex with Mad1p" |
| 2855 | YJL031C | BET4 SGDID:S000003568, Chr X from 387433-387431,387343-386363, reverse complement, Verified ORF, "Alpha subunit of Type II geranylgeranyltransferase required for vesicular transport between the endoplasmic reticulum and the Golgi; provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p" |
| 2856 | YJL033W | HCA4 SGDID:S000003570, Chr X from 383832-386144, Verified ORF, "Putative nucleolar DEAD box RNA helicase; high-copy number suppression of a U14 snoRNA processing mutant suggests an involvement in 18S rRNA synthesis" |
| 2857 | YJL034W | KAR2 SGDID:S000003571, Chr X from 381322-383370, Verified ORF, "ATPase involved in protein import into the ER, also acts as a chaperone to mediate protein folding in the ER and may play a role in ER export of soluble proteins; regulates the unfolded protein response via interaction with Ire1p" |
| 2858 | YJL035C | TAD2 SGDID:S000003572, Chr X from 380996-380244, reverse complement, Verified ORF, "Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad3p that converts adenosine to inosine at the wobble position of several tRNAs" |
| 2859 | YJL036W | SNX4 SGDID:S000003573, Chr X from 378820-380091, Verified ORF, "Sorting nexin, involved in the retrieval of late-Golgi SNAREs from the post-Golgi endosome to the trans-Golgi network and in cytoplasm to vacuole transport; contains a PX domain; forms complexes with Snx41p and with Atg20p" |
| 2860 | YJL037W | IRC18 SGDID:S000003574, Chr X from 376657-377331, Verified ORF, "Putative protein of unknown function; expression induced in respiratory-deficient cells and in carbon-limited chemostat cultures; similar to adjacent ORF, YJL038C; null mutant displays increased levels of spontaneous Rad52p foci" |
| 2861 | YJL038C | YJL038C SGDID:S000003575, Chr X from 375769-375110, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; expression induced during sporulation and repressed during vegetative growth by Sum1p and Hst1p; similar to adjacent open reading frame, YJL037W" |
| 2862 | YJL039C | NUP192 SGDID:S000003576, Chr X from 373794-368743, reverse complement, Verified ORF, "Essential structural subunit of the nuclear pore complex (NPC), localizes to the nuclear periphery of nuclear pores, homologous to human p205" |
| 2863 | YJL041W | NSP1 SGDID:S000003577, Chr X from 365779-365779,365898-368368, Verified ORF, "Essential component of the nuclear pore complex, which mediates nuclear import and export" |
| 2864 | YJL042W | MHP1 SGDID:S000003578, Chr X from 361244-365440, Verified ORF, "Microtubule-associated protein involved in assembly and stabilization of microtubules; overproduction results in cell cycle arrest at G2 phase; similar to Drosophila protein MAP and to mammalian MAP4 proteins" |
| 2865 | YJL043W | YJL043W SGDID:S000003579, Chr X from 360125-360898, Uncharacterized ORF, "Putative protein of unknown function; YJL043W is a non-essential gene" |
| 2866 | YJL044C | GYP6 SGDID:S000003580, Chr X from 359671-358295, reverse complement, Verified ORF, "GTPase-activating protein (GAP) for the yeast Rab family member, Ypt6p; involved in vesicle mediated protein transport" |
| 2867 | YJL045W | YJL045W SGDID:S000003581, Chr X from 356019-357923, Uncharacterized ORF, "Minor succinate dehydrogenase isozyme; homologous to Sdh1p, the major isozyme reponsible for the oxidation of succinate and transfer of electrons to ubiquinone; induced during the diauxic shift in a Cat8p-dependent manner" |
| 2868 | YJL046W | YJL046W SGDID:S000003582, Chr X from 352381-353610, Uncharacterized ORF, "Putative lipoate-protein ligase A family member; null mutant displays respiratory growth defect, decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media" |
| 2869 | YJL047C | RTT101 SGDID:S000003583, Chr X from 352103-349575, reverse complement, Verified ORF, "Cullin subunit of a Roc1p-dependent E3 ubiquitin ligase complex; deletion phenotype suggests a role in anaphase progression; interacts with Mms22p and implicated in Mms22-dependent DNA repair; modified by the ubiquitin-like protein, Rub1p" |
| 2870 | YJL047C-A | YJL047C-A SGDID:S000028804, Chr X from 349173-349039, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 2871 | YJL048C | UBX6 SGDID:S000003584, Chr X from 348632-347442, reverse complement, Verified ORF, "UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p, transcription is repressed when cells are grown in media containing inositol and choline" |
| 2872 | YJL049W | YJL049W SGDID:S000003585, Chr X from 345968-347320, Uncharacterized ORF, "Putative protein of unknown function; YJL049W is a non-essential gene" |
| 2873 | YJL050W | MTR4 SGDID:S000003586, Chr X from 342517-345738, Verified ORF, "Dead-box family ATP dependent helicase required for mRNA export from the nucleus; co-factor of the exosome complex, required for 3' end formation of 5.8S rRNA" |
| 2874 | YJL051W | IRC8 SGDID:S000003587, Chr X from 339782-342250, Verified ORF, "Bud tip localized protein of unknown function; mRNA is targeted to the bud by a She2p dependent transport system; mRNA is cell cycle regulated via Fkh2p, peaking in G2/M phase; null mutant displays increased levels of spontaneous Rad52p foc" |
| 2875 | YJL052C-A | YJL052C-A SGDID:S000007610, Chr X from 337998-337879, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, identified based on comparison to related yeast species" |
| 2876 | YJL052W | TDH1 SGDID:S000003588, Chr X from 338266-339264, Verified ORF, "Glyceraldehyde-3-phosphate dehydrogenase, isozyme 1, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall" |
| 2877 | YJL053W | PEP8 SGDID:S000003589, Chr X from 335893-337032, Verified ORF, "Vacuolar protein sorting protein that forms part of the multimeric membrane-associated retromer complex along with Vps35p, Vps29p, Vps17p, and Vps5p; essential for endosome-to-Golgi retrograde protein transport" |
| 2878 | YJL054W | TIM54 SGDID:S000003590, Chr X from 334260-335696, Verified ORF, "Component of the mitochondrial Tim54p-Tim22p complex involved in insertion of polytopic proteins into the inner membrane" |
| 2879 | YJL055W | YJL055W SGDID:S000003591, Chr X from 333352-334089, Uncharacterized ORF, "Putative protein of unknown function, proposed to be involved in the metabolism of purine and pyrimidine base analogues; deletion mutants are sensitive to HAP and AHA; overexpression confers resistance to 5-FOA and 5-FU" |
| 2880 | YJL056C | ZAP1 SGDID:S000003592, Chr X from 333068-330426, reverse complement, Verified ORF, "Zinc-regulated transcription factor, binds to zinc-responsive promoter elements to induce transcription of certain genes in the presence of zinc; regulates its own transcription; contains seven zinc-finger domains" |
| 2881 | YJL057C | IKS1 SGDID:S000003593, Chr X from 330116-328113, reverse complement, Verified ORF, "Putative serine/threonine kinase; expression is induced during mild heat stress; deletion mutants are hypersensitive to copper sulphate and resistant to sorbate; interacts with an N-terminal fragment of Sst2p" |
| 2882 | YJL058C | BIT61 SGDID:S000003594, Chr X from 327868-326237, reverse complement, Verified ORF, "Subunit of TORC2 (Tor2p-Lst8p-Avo1-Avo2-Tsc11p-Bit61p-Slm1p-Slm2p), a membrane-associated complex that regulates cell cycle-dependent actin cytoskeletal dynamics during polarized growth and cell wall integrity" |
| 2883 | YJL059W | YHC3 SGDID:S000003595, Chr X from 324959-326185, Verified ORF, "Vacuolar membrane protein involved in the ATP-dependent transport of arginine into the vacuole and possibly in balancing ion homeostasis; homolog of human CLN3 involved in Batten disease (juvenile onset neuronal ceroid lipofuscinosis)" |
| 2884 | YJL060W | BNA3 SGDID:S000003596, Chr X from 323381-324715, Verified ORF, "Kynurenine aminotransferase, catalyzes formation of kynurenic acid from kynurenine; potential Cdc28p substrate" |
| 2885 | YJL061W | NUP82 SGDID:S000003597, Chr X from 320011-322152, Verified ORF, "Nucleoporin, subunit of the nuclear pore complex (NPC); forms a subcomplex with Nup159p and Nsp1p, interacts with Nup116p and is required for proper localization of Nup116p in the NPC" |
| 2886 | YJL062W | LAS21 SGDID:S000003598, Chr X from 317279-319771, Verified ORF, "Integral plasma membrane protein involved in the synthesis of the glycosylphosphatidylinositol (GPI) core structure; mutations affect cell wall integrity" |
| 2887 | YJL062W-A | YJL062W-A SGDID:S000007611, Chr X from 316718-316975, Uncharacterized ORF, "Putative protein of unknown function, identified based on comparison to related yeast species; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2888 | YJL063C | MRPL8 SGDID:S000003599, Chr X from 316470-315754, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 2889 | YJL065C | DLS1 SGDID:S000003601, Chr X from 315552-315049, reverse complement, Verified ORF, "Subunit of ISW2/yCHRAC chromatin accessibility complex along with Itc1p, Isw2p, and Dpb4p; involved in inheritance of telomeric silencing" |
| 2890 | YJL066C | MPM1 SGDID:S000003602, Chr X from 314867-314109, reverse complement, Verified ORF, "Mitochondrial membrane protein of unknown function, contains no hydrophobic stretches" |
| 2891 | YJL068C | YJL068C SGDID:S000003604, Chr X from 313910-313011, reverse complement, Verified ORF, "Non-essential intracellular esterase that can function as an S-formylglutathione hydrolase; may be involved in the detoxification of formaldehyde, which can be metabolized to S-formylglutathione; similar to human esterase D" |
| 2892 | YJL069C | UTP18 SGDID:S000003605, Chr X from 312701-310917, reverse complement, Verified ORF, "Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data" |
| 2893 | YJL070C | YJL070C SGDID:S000003606, Chr X from 310632-307966, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with similarity to AMP deaminases; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YJL070C is a non-essential gene" |
| 2894 | YJL071W | ARG2 SGDID:S000003607, Chr X from 306127-307851, Verified ORF, "Acetylglutamate synthase (glutamate N-acetyltransferase), mitochondrial enzyme that catalyzes the first step in the biosynthesis of the arginine precursor ornithine; forms a complex with Arg5,6p" |
| 2895 | YJL072C | PSF2 SGDID:S000003608, Chr X from 305857-305216, reverse complement, Verified ORF, "Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery" |
| 2896 | YJL073W | JEM1 SGDID:S000003609, Chr X from 303176-305113, Verified ORF, "DnaJ-like chaperone required for nuclear membrane fusion during mating, localizes to the ER membrane; exhibits genetic interactions with KAR2" |
| 2897 | YJL074C | SMC3 SGDID:S000003610, Chr X from 302844-299152, reverse complement, Verified ORF, "Subunit of the multiprotein cohesin complex required for sister chromatid cohesion in mitotic cells; also required, with Rec8p, for cohesion and recombination during meiosis; phylogenetically conserved SMC chromosomal ATPase family member" |
| 2898 | YJL076W | NET1 SGDID:S000003612, Chr X from 295240-298809, Verified ORF, "Core subunit of the RENT complex, which is a complex involved in nucleolar silencing and telophase exit; stimulates transcription by RNA polymerase I and regulates nucleolar structure" |
| 2899 | YJL077C | ICS3 SGDID:S000003613, Chr X from 295056-294661, reverse complement, Verified ORF, "Protein of unknown function" |
| 2900 | YJL077W-B | YJL077W-B SGDID:S000028662, Chr X from 294042-294140, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 2901 | YJL078C | PRY3 SGDID:S000003614, Chr X from 293976-291331, reverse complement, Verified ORF, "Protein of unknown function, has similarity to Pry1p and Pry2p and to the plant PR-1 class of pathogen related proteins" |
| 2902 | YJL079C | PRY1 SGDID:S000003615, Chr X from 290769-289870, reverse complement, Verified ORF, "Protein of unknown function, has similarity to Pry2p and Pry3p and to the plant PR-1 class of pathogen related proteins" |
| 2903 | YJL080C | SCP160 SGDID:S000003616, Chr X from 289221-285553, reverse complement, Verified ORF, "Essential RNA-binding G protein effector of mating response pathway, mainly associated with nuclear envelope and ER, interacts in mRNA-dependent manner with translating ribosomes via multiple KH domains, similar to vertebrate vigilins" |
| 2904 | YJL081C | ARP4 SGDID:S000003617, Chr X from 285266-283797, reverse complement, Verified ORF, "Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes" |
| 2905 | YJL082W | IML2 SGDID:S000003618, Chr X from 281180-283375, Verified ORF, "Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2906 | YJL083W | TAX4 SGDID:S000003619, Chr X from 278836-280650, Verified ORF, "EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS" |
| 2907 | YJL084C | ALY2 SGDID:S000003620, Chr X from 277997-274857, reverse complement, Verified ORF, "Cytoplasmic protein of unknown function that interacts with the cyclin Pcl7p; phosphorylated in vitro by the cyclin-CDK complex, Pcl7p-Pho85p; identified as a potential Cdc28p substrate; mRNA is cell cycle regulated, peaking in M phase" |
| 2908 | YJL085W | EXO70 SGDID:S000003621, Chr X from 272822-274693, Verified ORF, "Essential 70kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis" |
| 2909 | YJL087C | TRL1 SGDID:S000003623, Chr X from 272480-269997, reverse complement, Verified ORF, "tRNA ligase, required for tRNA splicing; composed of three essential domains containing the phosphodiesterase, polynucleotide kinase, and ligase activities required for ligation; localized at the inner membrane of the nuclear envelope" |
| 2910 | YJL088W | ARG3 SGDID:S000003624, Chr X from 268794-269810, Verified ORF, "Ornithine carbamoyltransferase (carbamoylphosphate:L-ornithine carbamoyltransferase), catalyzes the sixth step in the biosynthesis of the arginine precursor ornithine" |
| 2911 | YJL089W | SIP4 SGDID:S000003625, Chr X from 265921-268410, Verified ORF, "C6 zinc cluster transcriptional activator that binds to the carbon source-responsive element (CSRE) of gluconeogenic genes; involved in the positive regulation of gluconeogenesis; regulated by Snf1p protein kinase; localized to the nucleus" |
| 2912 | YJL090C | DPB11 SGDID:S000003626, Chr X from 265046-262752, reverse complement, Verified ORF, "Subunit of DNA Polymerase II Epsilon complex; has BRCT domain, required on the prereplicative complex at replication origins for loading DNA polymerases to initiate DNA synthesis, also required for S/M checkpoint control" |
| 2913 | YJL091C | GWT1 SGDID:S000003627, Chr X from 262547-261075, reverse complement, Verified ORF, "Protein involved in the inositol acylation of glucosaminyl phosphatidylinositol (GlcN-PI) to form glucosaminyl(acyl)phosphatidylinositol (GlcN(acyl)PI), an intermediate in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors" |
| 2914 | YJL092W | SRS2 SGDID:S000003628, Chr X from 257418-260942, Verified ORF, "DNA helicase and DNA-dependent ATPase involved in DNA repair, needed for proper timing of commitment to meiotic recombination and transition from Meiosis I to II; affects genome stability by suppressing unscheduled homologous recombination" |
| 2915 | YJL093C | TOK1 SGDID:S000003629, Chr X from 256807-254732, reverse complement, Verified ORF, "Outward-rectifier potassium channel of the plasma membrane with two pore domains in tandem, each of which forms a functional channel permeable to potassium; carboxy tail functions to prevent inner gate closures; target of K1 toxin" |
| 2916 | YJL094C | KHA1 SGDID:S000003630, Chr X from 254437-251816, reverse complement, Verified ORF, "Putative K+/H+ antiporter with a probable role in intracellular cation homeostasis, localized to Golgi vesicles and detected in highly purified mitochondria in high-throughput studies" |
| 2917 | YJL095W | BCK1 SGDID:S000003631, Chr X from 247250-251686, Verified ORF, "Mitogen-activated protein (MAP) kinase kinase kinase acting in the protein kinase C signaling pathway, which controls cell integrity; upon activation by Pkc1p phosphorylates downstream kinases Mkk1p and Mkk2p" |
| 2918 | YJL096W | MRPL49 SGDID:S000003632, Chr X from 246486-246971, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 2919 | YJL097W | PHS1 SGDID:S000003633, Chr X from 245587-246240, Verified ORF, "Essential 3-hydroxyacyl-CoA dehydratase of the ER membrane, involved in elongation of very long-chain fatty acids; evolutionarily conserved, similar to mammalian PTPLA and PTPLB; involved in sphingolipid biosynthesis and protein trafficking" |
| 2920 | YJL098W | SAP185 SGDID:S000003634, Chr X from 242078-245254, Verified ORF, "Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap155p, and Sap190p" |
| 2921 | YJL099W | CHS6 SGDID:S000003635, Chr X from 239410-241650, Verified ORF, "Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane" |
| 2922 | YJL100W | LSB6 SGDID:S000003636, Chr X from 237259-239082, Verified ORF, "Type II phosphatidylinositol 4-kinase that binds Las17p, which is a homolog of human Wiskott-Aldrich Syndrome protein involved in actin patch assembly and actin polymerization" |
| 2923 | YJL101C | GSH1 SGDID:S000003637, Chr X from 236352-234316, reverse complement, Verified ORF, "Gamma glutamylcysteine synthetase catalyzes the first step in glutathione (GSH) biosynthesis; expression induced by oxidants, cadmium, and mercury" |
| 2924 | YJL102W | MEF2 SGDID:S000003638, Chr X from 231297-233756, Verified ORF, "Mitochondrial elongation factor involved in translational elongation" |
| 2925 | YJL103C | YJL103C SGDID:S000003639, Chr X from 230877-229021, reverse complement, Uncharacterized ORF, "Putative zinc cluster protein of unknown function; proposed to be involved in the regulation of energy metabolism, based on patterns of expression and sequence analysis" |
| 2926 | YJL104W | PAM16 SGDID:S000003640, Chr X from 227323-227772, Verified ORF, "Constituent of the mitochondrial import motor associated with the presequence translocase, along with Ssc1p, Tim44p, Mge1p, and Pam18p; forms a 1:1 subcomplex with Pam18p and inhibits its cochaperone activity; contains J-like domain" |
| 2927 | YJL105W | SET4 SGDID:S000003641, Chr X from 225051-226733, Verified ORF, "Protein of unknown function, contains a SET domain" |
| 2928 | YJL106W | IME2 SGDID:S000003642, Chr X from 221386-223323, Verified ORF, "Serine/threonine protein kinase involved in activation of meiosis, associates with Ime1p and mediates its stability, activates Ndt80p; IME2 expression is positively regulated by Ime1p" |
| 2929 | YJL107C | YJL107C SGDID:S000003643, Chr X from 220012-218849, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; expression is induced by activation of the HOG1 mitogen-activated signaling pathway and this induction is Hog1p/Pbs2p dependent; YJL107C and adjacent ORF, YJL108C are merged in related fungi" |
| 2930 | YJL108C | PRM10 SGDID:S000003644, Chr X from 218852-217701, reverse complement, Verified ORF, "Pheromone-regulated protein, predicted to have 5 transmembrane segments; induced by treatment with 8-methoxypsoralen and UVA irradiation" |
| 2931 | YJL109C | UTP10 SGDID:S000003645, Chr X from 217305-211996, reverse complement, Verified ORF, "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" |
| 2932 | YJL110C | GZF3 SGDID:S000003646, Chr X from 211573-209918, reverse complement, Verified ORF, "GATA zinc finger protein and Dal80p homolog that negatively regulates nitrogen catabolic gene expression by competing with Gat1p for GATA site binding; function requires a repressive carbon source; dimerizes with Dal80p and binds to Tor1p" |
| 2933 | YJL111W | CCT7 SGDID:S000003647, Chr X from 207873-209525, Verified ORF, "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" |
| 2934 | YJL112W | MDV1 SGDID:S000003648, Chr X from 205301-207445, Verified ORF, "Peripheral protein of the cytosolic face of the mitochondrial outer membrane, required for mitochondrial fission; interacts with Fis1p and with the dynamin-related GTPase Dnm1p; contains WD repeats" |
| 2935 | YJL113W | YJL113W SGDID:S000003649, Chr X from 197913-198998,199000-203325, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 2936 | YJL114W | YJL114W SGDID:S000003650, Chr X from 197913-199157, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 2937 | YJL115W | ASF1 SGDID:S000003651, Chr X from 196285-197124, Verified ORF, "Nucleosome assembly factor, involved in chromatin assembly and disassembly, anti-silencing protein that causes derepression of silent loci when overexpressed; plays a role in regulating Ty1 transposition" |
| 2938 | YJL116C | NCA3 SGDID:S000003652, Chr X from 194872-193859, reverse complement, Verified ORF, "Protein that functions with Nca2p to regulate mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p ) of the Fo-F1 ATP synthase; member of the SUN family" |
| 2939 | YJL117W | PHO86 SGDID:S000003653, Chr X from 192530-193465, Verified ORF, "Endoplasmic reticulum (ER) resident protein required for ER exit of the high-affinity phosphate transporter Pho84p, specifically required for packaging of Pho84p into COPII vesicles" |
| 2940 | YJL118W | YJL118W SGDID:S000003654, Chr X from 191638-192297, Verified ORF, "Putative protein of unknown function; may interact with ribosomes, based on co-purification experiments; YJL18W is a non-essential gene; deletion enhances the toxicity of heterologously expressed human alpha-synuclein" |
| 2941 | YJL121C | RPE1 SGDID:S000003657, Chr X from 191089-190373, reverse complement, Verified ORF, "D-ribulose-5-phosphate 3-epimerase, catalyzes a reaction in the non-oxidative part of the pentose-phosphate pathway; mutants are sensitive to oxidative stress" |
| 2942 | YJL122W | ALB1 SGDID:S000003658, Chr X from 189715-190242, Verified ORF, "Shuttling pre-60S factor; involved in the biogenesis of ribosomal large subunit; interacts directly with Arx1p; responsible for Tif6p recycling defects in absence of Rei1p" |
| 2943 | YJL123C | YJL123C SGDID:S000003659, Chr X from 189439-188003, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to COPI-coated vesicles (early Golgi); YJL123C is synthetically lethal with cdc13-1" |
| 2944 | YJL124C | LSM1 SGDID:S000003660, Chr X from 187643-187125, reverse complement, Verified ORF, "Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) involved in degradation of cytoplasmic mRNAs" |
| 2945 | YJL125C | GCD14 SGDID:S000003661, Chr X from 186677-185526, reverse complement, Verified ORF, "Subunit of tRNA (1-methyladenosine) methyltransferase, with Gcd10p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression" |
| 2946 | YJL126W | NIT2 SGDID:S000003662, Chr X from 184499-185422, Verified ORF, "Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member" |
| 2947 | YJL127C | SPT10 SGDID:S000003663, Chr X from 184218-182296, reverse complement, Verified ORF, "Putative histone acetylase, sequence-specific activator of histone genes, binds specifically and highly cooperatively to pairs of UAS elements in core histone promoters, functions at or near the TATA box" |
| 2948 | YJL127C-B | YJL127C-B SGDID:S000028522, Chr X from 181707-181549, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified based on homology to the filamentous fungus, Ashbya gossypii" |
| 2949 | YJL128C | PBS2 SGDID:S000003664, Chr X from 180100-178094, reverse complement, Verified ORF, "MAP kinase kinase that plays a pivotal role in the osmosensing signal-transduction pathway, activated under severe osmotic stress; plays a role in regulating Ty1 transposition" |
| 2950 | YJL129C | TRK1 SGDID:S000003665, Chr X from 177303-173596, reverse complement, Verified ORF, "Component of the Trk1p-Trk2p potassium transport system; 180 kDa high affinity potassium transporter; phosphorylated in vivo and interacts physically with the phosphatase Ppz1p, suggesting Trk1p acitivy is regulated by phosphorylation" |
| 2951 | YJL130C | URA2 SGDID:S000003666, Chr X from 172364-165720, reverse complement, Verified ORF, "Bifunctional carbamoylphosphate synthetase (CPSase)-aspartate transcarbamylase (ATCase), catalyzes the first two enzymatic steps in the de novo biosynthesis of pyrimidines; both activities are subject to feedback inhibition by UTP" |
| 2952 | YJL131C | YJL131C SGDID:S000003667, Chr X from 165345-164275, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic non-tagged protein is detected in highly purified mitochondria; null mutant is viable, displays increased frequency of mitochondrial genome loss (petite formation)" |
| 2953 | YJL132W | YJL132W SGDID:S000003668, Chr X from 161911-164163, Uncharacterized ORF, "Putative protein of unknown function; localizes to the membrane fraction; possible Zap1p-regulated target gene induced by zinc deficiency; YJL132W is a non-essential gene" |
| 2954 | YJL133C-A | YJL133C-A SGDID:S000028805, Chr X from 159844-159620, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2955 | YJL133W | MRS3 SGDID:S000003669, Chr X from 160616-161560, Verified ORF, "Mitochondrial iron transporter of the mitochondrial carrier family (MCF), very similar to and functionally redundant with Mrs4p; functions under low-iron conditions; may transport other cations in addition to iron" |
| 2956 | YJL134W | LCB3 SGDID:S000003670, Chr X from 158185-159414, Verified ORF, "Long-chain base-1-phosphate phosphatase with specificity for dihydrosphingosine-1-phosphate, regulates ceramide and long-chain base phosphates levels, involved in incorporation of exogenous long chain bases in sphingolipids" |
| 2957 | YJL136C | RPS21B SGDID:S000003672, Chr X from 157270-157247,156786-156547, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Ap and has similarity to rat S21 ribosomal protein" |
| 2958 | YJL136W-A | YJL136W-A SGDID:S000028806, Chr X from 156166-156249, Uncharacterized ORF, "Identified by SAGE" |
| 2959 | YJL137C | GLG2 SGDID:S000003673, Chr X from 156124-154982, reverse complement, Verified ORF, "Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin" |
| 2960 | YJL138C | TIF2 SGDID:S000003674, Chr X from 154688-153501, reverse complement, Verified ORF, "Translation initiation factor eIF4A, identical to Tif1p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G" |
| 2961 | YJL139C | YUR1 SGDID:S000003675, Chr X from 152996-151710, reverse complement, Verified ORF, "Mannosyltransferase of the KTR1 family, involved in protein N-glycosylation; located in the Golgi apparatus" |
| 2962 | YJL140W | RPB4 SGDID:S000003676, Chr X from 150958-151623, Verified ORF, "RNA polymerase II subunit B32; forms two subunit dissociable complex with Rpb7p; involved recruitment of 3'-end processing factors to transcribing RNA polymerase II complex and in export of mRNA to cytoplasm under stress conditions" |
| 2963 | YJL141C | YAK1 SGDID:S000003677, Chr X from 150387-147964, reverse complement, Verified ORF, "Serine-threonine protein kinase that is part of a glucose-sensing system involved in growth control in response to glucose availability; translocates from the cytoplasm to the nucleus and phosphorylates Pop2p in response to a glucose signal" |
| 2964 | YJL143W | TIM17 SGDID:S000003679, Chr X from 147098-147574, Verified ORF, "Essential constituent of the mitochondrial inner membrane presequence translocase; interacts with Pam18p to recruit the presequence translocase-associated motor (PAM complex) and also required for protein sorting during import" |
| 2965 | YJL144W | YJL144W SGDID:S000003680, Chr X from 146356-146670, Uncharacterized ORF, "Cytoplasmic hydrophilin of unknown function, possibly involved in the dessication response; expression induced by osmotic stress, starvation and during stationary phase; GFP-fusion protein is induced by the DNA-damaging agent MMS" |
| 2966 | YJL145W | SFH5 SGDID:S000003681, Chr X from 145157-146041, Verified ORF, "Putative phosphatidylinositol transfer protein (PITP), exhibits phosphatidylinositol- but not phosphatidylcholine-transfer activity, localized to cytosol and microsomes, similar to Sec14p; may be PITP regulator rather than actual PITP" |
| 2967 | YJL146W | IDS2 SGDID:S000003682, Chr X from 143289-144698, Verified ORF, "Protein involved in modulation of Ime2p activity during meiosis, appears to act indirectly to promote Ime2p-mediated late meiotic functions; found in growing cells and degraded during sporulation" |
| 2968 | YJL147C | YJL147C SGDID:S000003683, Chr X from 142564-141416, reverse complement, Uncharacterized ORF, "Mitochondrial protein of unknown function; homozygous diploid deletion strain has a sporulation defect characterized by elevated dityrosine in the soluble fraction; expression induced by calcium shortage; YJL147W is a non-essential gene" |
| 2969 | YJL148W | RPA34 SGDID:S000003684, Chr X from 140434-141135, Verified ORF, "RNA polymerase I subunit A34.5" |
| 2970 | YJL149W | YJL149W SGDID:S000003685, Chr X from 137376-139367, Verified ORF, "Putative SCF ubiquitin ligase F-box protein; interacts physically with both Cdc53p and Skp1 and genetically with CDC34; similar to putative F-box protein YDR131C; null mutant suppresses dst1delta sensitivity for 6-azauracil" |
| 2971 | YJL151C | SNA3 SGDID:S000003687, Chr X from 136770-136369, reverse complement, Verified ORF, "Integral membrane protein localized to vacuolar intralumenal vesicles, computational analysis of large-scale protein-protein interaction data suggests a possible role in either cell wall synthesis or protein-vacuolar targeting" |
| 2972 | YJL153C | INO1 SGDID:S000003689, Chr X from 135930-134329, reverse complement, Verified ORF, "Inositol 1-phosphate synthase, involved in synthesis of inositol phosphates and inositol-containing phospholipids; transcription is coregulated with other phospholipid biosynthetic genes by Ino2p and Ino4p, which bind the UASINO DNA element" |
| 2973 | YJL154C | VPS35 SGDID:S000003690, Chr X from 133932-131098, reverse complement, Verified ORF, "Endosomal subunit of membrane-associated retromer complex required for retrograde transport; receptor that recognizes retrieval signals on cargo proteins, forms subcomplex with Vps26p and Vps29p that selects cargo proteins for retrieval" |
| 2974 | YJL155C | FBP26 SGDID:S000003691, Chr X from 130640-129282, reverse complement, Verified ORF, "Fructose-2,6-bisphosphatase, required for glucose metabolism" |
| 2975 | YJL156C | SSY5 SGDID:S000003692, Chr X from 128949-126886, reverse complement, Verified ORF, "Probable serine protease of the SPS plasma membrane amino acid sensor system (Ssy1p-Ptr3p-Ssy5p), which senses external amino acid concentration and transmits intracellular signals that regulate expression of amino acid permease genes" |
| 2976 | YJL157C | FAR1 SGDID:S000003693, Chr X from 126324-123832, reverse complement, Verified ORF, "Cyclin-dependent kinase inhibitor that mediates cell cycle arrest in response to pheromone; also forms a complex with Cdc24p, Ste4p, and Ste18p that may specify the direction of polarized growth during mating; potential Cdc28p substrate" |
| 2977 | YJL158C | CIS3 SGDID:S000003694, Chr X from 122944-122261, reverse complement, Verified ORF, "Mannose-containing glycoprotein constituent of the cell wall; member of the PIR (proteins with internal repeats) family" |
| 2978 | YJL159W | HSP150 SGDID:S000003695, Chr X from 120445-121686, Verified ORF, "O-mannosylated heat shock protein that is secreted and covalently attached to the cell wall via beta-1,3-glucan and disulfide bridges; required for cell wall stability; induced by heat shock, oxidative stress, and nitrogen limitation" |
| 2979 | YJL160C | YJL160C SGDID:S000003696, Chr X from 118821-117958, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; member of the PIR (proteins with internal repeats) family of cell wall proteins; non-essential gene that is required for sporulation; mRNA is weakly cell cycle regulated, peaking in mitosis" |
| 2980 | YJL161W | YJL161W SGDID:S000003697, Chr X from 117241-117783, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 2981 | YJL162C | JJJ2 SGDID:S000003698, Chr X from 115625-113874, reverse complement, Verified ORF, "Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein" |
| 2982 | YJL163C | YJL163C SGDID:S000003699, Chr X from 113329-111662, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 2983 | YJL164C | TPK1 SGDID:S000003700, Chr X from 111153-109960, reverse complement, Verified ORF, "cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk2p and Tpk3p" |
| 2984 | YJL165C | HAL5 SGDID:S000003701, Chr X from 109455-106888, reverse complement, Verified ORF, "Putative protein kinase; overexpression increases sodium and lithium tolerance, whereas gene disruption increases cation and low pH sensitivity and impairs potassium uptake, suggesting a role in regulation of Trk1p and/or Trk2p transporters" |
| 2985 | YJL166W | QCR8 SGDID:S000003702, Chr X from 106428-106712, Verified ORF, "Subunit 8 of ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; oriented facing the intermembrane space; expression is regulated by Abf1p and Cpf1p" |
| 2986 | YJL167W | ERG20 SGDID:S000003703, Chr X from 105008-106066, Verified ORF, "Farnesyl pyrophosphate synthetase, has both dimethylallyltranstransferase and geranyltranstransferase activities; catalyzes the formation of C15 farnesyl pyrophosphate units for isoprenoid and sterol biosynthesis" |
| 2987 | YJL168C | SET2 SGDID:S000003704, Chr X from 104422-102221, reverse complement, Verified ORF, "Histone methyltransferase with a role in transcriptional elongation, methylates a lysine residue of histone H3; associates with the C-terminal domain of Rpo21p; histone methylation activity is regulated by phosphorylation status of Rpo21p" |
| 2988 | YJL170C | ASG7 SGDID:S000003706, Chr X from 101773-101144, reverse complement, Verified ORF, "Protein that regulates signaling from a G protein beta subunit Ste4p and its relocalization within the cell; specific to a-cells and induced by alpha-factor" |
| 2989 | YJL171C | YJL171C SGDID:S000003707, Chr X from 100888-99698, reverse complement, Verified ORF, "GPI-anchored cell wall protein of unknown function; induced in response to cell wall damaging agents and by mutations in genes involved in cell wall biogenesis; sequence similarity to YBR162C/TOS1, a covalently bound cell wall protein" |
| 2990 | YJL172W | CPS1 SGDID:S000003708, Chr X from 97731-99461, Verified ORF, "Vacuolar carboxypeptidase yscS; expression is induced under low-nitrogen conditions" |
| 2991 | YJL173C | RFA3 SGDID:S000003709, Chr X from 96527-96159, reverse complement, Verified ORF, "Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination" |
| 2992 | YJL174W | KRE9 SGDID:S000003710, Chr X from 95090-95920, Verified ORF, "Glycoprotein involved in cell wall beta-glucan assembly; null mutation leads to severe growth defects, aberrant multibudded morphology, and mating defects" |
| 2993 | YJL176C | SWI3 SGDID:S000003712, Chr X from 94528-92051, reverse complement, Verified ORF, "Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2" |
| 2994 | YJL177W | RPL17B SGDID:S000003713, Chr X from 90784-91092,91410-91655, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Ap and has similarity to E. coli L22 and rat L17 ribosomal proteins" |
| 2995 | YJL178C | ATG27 SGDID:S000003714, Chr X from 90095-89280, reverse complement, Verified ORF, "Type I membrane protein involved in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; may be involved in membrane delivery to the pre-autophagosomal structure; binds phosphatidylinositol 3-phosphate" |
| 2996 | YJL179W | PFD1 SGDID:S000003715, Chr X from 88785-89114, Verified ORF, "Subunit of heterohexameric prefoldin, which binds cytosolic chaperonin and transfers target proteins to it; involved in the biogenesis of actin and of alpha- and gamma-tubulin" |
| 2997 | YJL180C | ATP12 SGDID:S000003716, Chr X from 88558-87581, reverse complement, Verified ORF, "Conserved protein required for assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase; mutation of human ATP12 reduces active ATP synthase levels and is associated with the disorder ATPAF2 deficiency" |
| 2998 | YJL181W | YJL181W SGDID:S000003717, Chr X from 85658-87493, Uncharacterized ORF, "Putative protein of unknown function; expression is cell-cycle regulated as shown by microarray analysis" |
| 2999 | YJL183W | MNN11 SGDID:S000003719, Chr X from 84066-85334, Verified ORF, "Subunit of a Golgi mannosyltransferase complex that also contains Anp1p, Mnn9p, Mnn10p, and Hoc1p, and mediates elongation of the polysaccharide mannan backbone; has homology to Mnn10p" |
| 3000 | YJL184W | GON7 SGDID:S000003720, Chr X from 83446-83817, Verified ORF, "Protein proposed to be involved in the modification of N-linked oligosaccharides, osmotic stress response, telomere uncapping and elongation, transcription; component of the EKC/KEOPS protein complex with Kae1p, Cgi121p, Pcc1p, and Bud32p" |
| 3001 | YJL185C | YJL185C SGDID:S000003721, Chr X from 82974-82093, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; mRNA is weakly cell cycle regulated, peaking in G2 phase; YJL185C is a non-essential gene" |
| 3002 | YJL186W | MNN5 SGDID:S000003722, Chr X from 80153-81913, Verified ORF, "Alpha-1,2-mannosyltransferase, responsible for addition of the second alpha-1,2-linked mannose of the branches on the mannan backbone of oligosaccharides, localizes to an early Golgi compartment" |
| 3003 | YJL187C | SWE1 SGDID:S000003723, Chr X from 79261-76802, reverse complement, Verified ORF, "Protein kinase that regulates the G2/M transition by inhibition of Cdc28p kinase activity; localizes to the nucleus and to the daughter side of the mother-bud neck; homolog of S. pombe Wee1p; potential Cdc28p substrate" |
| 3004 | YJL189W | RPL39 SGDID:S000003725, Chr X from 75932-75937,76324-76473, Verified ORF, "Protein component of the large (60S) ribosomal subunit, has similarity to rat L39 ribosomal protein; required for ribosome biogenesis; exhibits genetic interactions with SIS1 and PAB1" |
| 3005 | YJL190C | RPS22A SGDID:S000003726, Chr X from 75301-74909, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Bp and has similarity to E. coli S8 and rat S15a ribosomal proteins" |
| 3006 | YJL191W | RPS14B SGDID:S000003727, Chr X from 73786-73795,74204-74610, Verified ORF, "Ribosomal protein 59 of the small subunit, required for ribosome assembly and 20S pre-rRNA processing; mutations confer cryptopleurine resistance; nearly identical to Rps14Ap and similar to E. coli S11 and rat S14 ribosomal proteins" |
| 3007 | YJL192C | SOP4 SGDID:S000003728, Chr X from 73413-72709, reverse complement, Verified ORF, "ER-membrane protein; suppressor of pma1-7, deletion of SOP4 slows down the export of wild-type Pma1p and Pma1-7 from the ER" |
| 3008 | YJL193W | YJL193W SGDID:S000003729, Chr X from 71365-72573, Uncharacterized ORF, "Putative protein of unknown function, predicted to encode a triose phosphate transporter subfamily member based on phylogenetic analysis; similar to YOR307C/SLY41; deletion mutant has a respiratory growth defect" |
| 3009 | YJL194W | CDC6 SGDID:S000003730, Chr X from 69337-70878, Verified ORF, "Essential ATP-binding protein required for DNA replication, component of the pre-replicative complex (pre-RC) which requires ORC to associate with chromatin and is in turn required for Mcm2-7p DNA association; homologous to S. pombe Cdc18p" |
| 3010 | YJL196C | ELO1 SGDID:S000003732, Chr X from 68781-67849, reverse complement, Verified ORF, "Elongase I, medium-chain acyl elongase, catalyzes carboxy-terminal elongation of unsaturated C12-C16 fatty acyl-CoAs to C16-C18 fatty acids" |
| 3011 | YJL197W | UBP12 SGDID:S000003733, Chr X from 63804-67568, Verified ORF, "Ubiquitin carboxyl-terminal hydrolase, ubiquitin-specific protease present in the nucleus and cytoplasm that cleaves ubiquitin from ubiquitinated proteins" |
| 3012 | YJL198W | PHO90 SGDID:S000003734, Chr X from 60843-63488, Verified ORF, "Low-affinity phosphate transporter; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth" |
| 3013 | YJL200C | ACO2 SGDID:S000003736, Chr X from 58813-56444, reverse complement, Verified ORF, "Putative mitochondrial aconitase isozyme; similarity to Aco1p, an aconitase required for the TCA cycle; expression induced during growth on glucose, by amino acid starvation via Gcn4p, and repressed on ethanol" |
| 3014 | YJL201W | ECM25 SGDID:S000003737, Chr X from 54379-56178, Verified ORF, "Non-essential protein of unknown function; promoter contains a consensus binding sequence for factor Abf1p" |
| 3015 | YJL203W | PRP21 SGDID:S000003739, Chr X from 53341-54183, Verified ORF, "Subunit of the SF3a splicing factor complex, required for spliceosome assembly" |
| 3016 | YJL204C | RCY1 SGDID:S000003740, Chr X from 53151-50629, reverse complement, Verified ORF, "F-box protein involved in recycling plasma membrane proteins internalized by endocytosis; localized to sites of polarized growth" |
| 3017 | YJL205C | NCE101 SGDID:S000003742, Chr X from 50443-50412,50268-50139, reverse complement, Verified ORF, "Protein of unknown function, involved in secretion of proteins that lack classical secretory signal sequences" |
| 3018 | YJL206C | YJL206C SGDID:S000003741, Chr X from 49935-47659, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; similar to transcriptional regulators from the Zn[2]-Cys[6] binuclear cluster protein family; mRNA is weakly cell cycle regulated, peaking in S phase; induced rapidly upon MMS treatment" |
| 3019 | YJL207C | LAA1 SGDID:S000003743, Chr X from 47433-41389, reverse complement, Verified ORF, "AP-1 accessory protein; colocalizes with clathrin to the late-Golgi apparatus; involved in TGN-endosome transport; physically interacts with AP-1; similar to the mammalian p200; may interact with ribosomes; YJL207C is a non-essential gene" |
| 3020 | YJL208C | NUC1 SGDID:S000003744, Chr X from 41183-40194, reverse complement, Verified ORF, "Major mitochondrial nuclease, has RNAse and DNA endo- and exonucleolytic activities; has roles in mitochondrial recombination, apoptosis and maintenance of polyploidy" |
| 3021 | YJL209W | CBP1 SGDID:S000003745, Chr X from 38005-39969, Verified ORF, "Mitochondrial protein that interacts with the 5'-untranslated region of the COB mRNA and has a role in its stability and translation; found in a complex at the inner membrane along with Pet309p" |
| 3022 | YJL210W | PEX2 SGDID:S000003746, Chr X from 36919-37734, Verified ORF, "RING-finger peroxin, peroxisomal membrane protein with a C-terminal zinc-binding RING domain, forms translocation subcomplex with Pex10p and Pex12p which functions in peroxisomal matrix protein import" |
| 3023 | YJL212C | OPT1 SGDID:S000003748, Chr X from 36249-33850, reverse complement, Verified ORF, "Proton-coupled oligopeptide transporter of the plasma membrane; also transports glutathione and phytochelatin; member of the OPT family" |
| 3024 | YJL213W | YJL213W SGDID:S000003749, Chr X from 32163-33158, Verified ORF, "Protein of unknown function that may interact with ribosomes; periodically expressed during the yeast metabolic cycle; phosphorylated in vitro by the mitotic exit network (MEN) kinase complex, Dbf2p/Mob1p" |
| 3025 | YJL214W | HXT8 SGDID:S000003750, Chr X from 26887-28596, Verified ORF, "Protein of unknown function with similarity to hexose transporter family members, expression is induced by low levels of glucose and repressed by high levels of glucose" |
| 3026 | YJL216C | YJL216C SGDID:S000003752, Chr X from 26086-24341, reverse complement, Uncharacterized ORF, "Protein of unknown function, similar to alpha-D-glucosidases; transcriptionally activated by both Pdr8p and Yrm1p, along with transporters and other genes involved in the pleiotropic drug resistance (PDR) phenomenon" |
| 3027 | YJL217W | YJL217W SGDID:S000003753, Chr X from 23133-23729, Uncharacterized ORF, "Cytoplasmic protein of unknown function; expression induced by calcium shortage and via the copper sensing transciption factor Mac1p during conditons of copper deficiency; mRNA is cell cycle regulated, peaking in G1 phase" |
| 3028 | YJL218W | YJL218W SGDID:S000003754, Chr X from 21973-22563, Uncharacterized ORF, "Putative protein of unknown function, similar to bacterial galactoside O-acetyltransferases; induced by oleate in an OAF1/PIP2-dependent manner; promoter contains an oleate response element consensus sequence; non-essential gene" |
| 3029 | YJL219W | HXT9 SGDID:S000003755, Chr X from 19497-21200, Verified ORF, "Putative hexose transporter that is nearly identical to Hxt11p, has similarity to major facilitator superfamily (MFS) transporters, expression of HXT9 is regulated by transcription factors Pdr1p and Pdr3p" |
| 3030 | YJL221C | FSP2 SGDID:S000003757, Chr X from 18536-16767, reverse complement, Verified ORF, "Protein of unknown function, expression is induced during nitrogen limitation" |
| 3031 | YJL222W | VTH2 SGDID:S000003758, Chr X from 11475-16124, Verified ORF, "Putative membrane glycoprotein with strong similarity to Vth1p and Pep1p/Vps10p, may be involved in vacuolar protein sorting" |
| 3032 | YJL223C | PAU1 SGDID:S000003759, Chr X from 9138-8776, reverse complement, Verified ORF, "Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme" |
| 3033 | YJL225C | YJL225C SGDID:S000003760, Chr X from 6130-4970,4581-466, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; similarity to DNA helicases that are also encoded within subtelomeric Y' elements and induced in telomerase deficient survivors" |
| 3034 | YJR001W | AVT1 SGDID:S000003761, Chr X from 436796-438604, Verified ORF, "Vacuolar transporter, imports large neutral amino acids into the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" |
| 3035 | YJR002W | MPP10 SGDID:S000003762, Chr X from 438858-440639, Verified ORF, "Component of the SSU processome and 90S preribosome, required for pre-18S rRNA processing, interacts with and controls the stability of Imp3p and Imp4p, essential for viability; similar to human Mpp10p" |
| 3036 | YJR003C | YJR003C SGDID:S000003763, Chr X from 442546-440987, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3037 | YJR004C | SAG1 SGDID:S000003764, Chr X from 444854-442902, reverse complement, Verified ORF, "Alpha-agglutinin of alpha-cells, binds to Aga1p during agglutination, N-terminal half is homologous to the immunoglobulin superfamily and contains binding site for a-agglutinin, C-terminal half is highly glycosylated and contains GPI anchor" |
| 3038 | YJR005C-A | YJR005C-A SGDID:S000028523, Chr X from 448751-448470, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, originally identified as a syntenic homolog of an Ashbya gossypii gene" |
| 3039 | YJR005W | APL1 SGDID:S000003765, Chr X from 445916-448018, Verified ORF, "Beta-adaptin, large subunit of the clathrin associated protein complex (AP-2); involved in vesicle mediated transport; similar to mammalian beta-chain of the clathrin associated protein complex" |
| 3040 | YJR006W | POL31 SGDID:S000003766, Chr X from 449195-450658, Verified ORF, "DNA polymerase III (delta) subunit, essential for cell viability; involved in DNA replication and DNA repair" |
| 3041 | YJR007W | SUI2 SGDID:S000003767, Chr X from 451013-451927, Verified ORF, "Alpha subunit of the translation initiation factor eIF2, involved in the identification of the start codon; phosphorylation of Ser51 is required for regulation of translation by inhibiting the exchange of GDP for GTP" |
| 3042 | YJR008W | YJR008W SGDID:S000003768, Chr X from 452423-453439, Uncharacterized ORF, "Putative protein of unknown function; expression repressed by inosine and choline in an Opi1p-dependent manner; expression induced by mild heat-stress on a non-fermentable carbon source." |
| 3043 | YJR009C | TDH2 SGDID:S000003769, Chr X from 454674-453676, reverse complement, Verified ORF, "Glyceraldehyde-3-phosphate dehydrogenase, isozyme 2, involved in glycolysis and gluconeogenesis; tetramer that catalyzes the reaction of glyceraldehyde-3-phosphate to 1,3 bis-phosphoglycerate; detected in the cytoplasm and cell-wall" |
| 3044 | YJR010C-A | SPC1 SGDID:S000003770, Chr X from 458354-458070, reverse complement, Verified ORF, "Subunit of the signal peptidase complex (SPC), which cleaves the signal sequence from proteins targeted to the endoplasmic reticulum (ER), homolog of the SPC12 subunit of mammalian signal peptidase complex" |
| 3045 | YJR010W | MET3 SGDID:S000003771, Chr X from 456232-457767, Verified ORF, "ATP sulfurylase, catalyzes the primary step of intracellular sulfate activation, essential for assimilatory reduction of sulfate to sulfide, involved in methionine metabolism" |
| 3046 | YJR011C | YJR011C SGDID:S000003772, Chr X from 459419-458634, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; GFP-fusion protein expression is induced in response to the DNA-damaging agent MMS" |
| 3047 | YJR012C | YJR012C SGDID:S000003773, Chr X from 460411-459788, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; proposed involvement in transport based on mass spectrometry analysis of copurifying proteins; partially overlaps neighboring ORF, GPI14/YJR013W" |
| 3048 | YJR013W | GPI14 SGDID:S000003774, Chr X from 460375-461586, Verified ORF, "Glycosylphosphatidylinositol-alpha 1,4 mannosyltransferase I, involved in GPI anchor biosynthesis, requires Pbn1p for function; homolog of mammalian PIG-M" |
| 3049 | YJR014W | TMA22 SGDID:S000003775, Chr X from 461822-462418, Verified ORF, "Protein of unknown function; associates with ribosomes and has a putative RNA binding domain; interacts with Tma20p; similar to human GRAP and human DRP1, which interacts with human Tma20p homolog MCT-1" |
| 3050 | YJR015W | YJR015W SGDID:S000003776, Chr X from 462714-464246, Uncharacterized ORF, "Putative protein of unknown function; localizes to the endoplasmic reticulum and cytoplasm; predicted to encode a membrane transporter based on phylogenetic analysis; YJR015W is a non-essential gene" |
| 3051 | YJR016C | ILV3 SGDID:S000003777, Chr X from 466201-464444, reverse complement, Verified ORF, "Dihydroxyacid dehydratase, catalyzes third step in the common pathway leading to biosynthesis of branched-chain amino acids" |
| 3052 | YJR017C | ESS1 SGDID:S000003778, Chr X from 467026-466514, reverse complement, Verified ORF, "Peptidylprolyl-cis/trans-isomerase (PPIase) specific for phosphorylated serine and threonine residues N-terminal to proline; regulates phosphorylation of the RNA polymerase II large subunit (Rpo21p) C-terminal domain" |
| 3053 | YJR019C | TES1 SGDID:S000003780, Chr X from 468274-467225, reverse complement, Verified ORF, "Peroxisomal acyl-CoA thioesterase likely to be involved in fatty acid oxidation rather than fatty acid synthesis; conserved protein also found in human peroxisomes; TES1 mRNA levels increase during growth on fatty acids" |
| 3054 | YJR021C | REC107 SGDID:S000003782, Chr X from 469572-469257,469176-468548, reverse complement, Verified ORF, "Protein involved in early stages of meiotic recombination; involved in coordination between the initiation of recombination and the first division of meiosis; part of a complex (Rec107p-Mei4p-Rec114p) required for ds break formation" |
| 3055 | YJR022W | LSM8 SGDID:S000003783, Chr X from 469777-470106, Verified ORF, "Lsm (Like Sm) protein; forms heteroheptameric complex (with Lsm2p, Lsm3p, Lsm4p, Lsm5p, Lsm6p, and Lsm7p) that is part of spliceosomal U6 snRNP and is also implicated in processing of pre-tRNA, pre-snoRNA, and pre-rRNA" |
| 3056 | YJR024C | YJR024C SGDID:S000003785, Chr X from 470957-470223, reverse complement, Uncharacterized ORF, "Putative methylthio-ribulose-1-phosphate dehydratase; acts in the methionine salvage pathway; potential Smt3p sumoylation substrate; expression downregulated by caspofungin and deletion mutant is caspofungin resistant" |
| 3057 | YJR025C | BNA1 SGDID:S000003786, Chr X from 471664-471131, reverse complement, Verified ORF, "3-hydroxyanthranilic acid dioxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p" |
| 3058 | YJR026W | YJR026W SGDID:S000003787, Chr X from 472753-474075, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 3059 | YJR027W | YJR027W SGDID:S000003788, Chr X from 472753-474054,474056-478021, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 3060 | YJR028W | YJR028W SGDID:S000003789, Chr X from 478337-479659, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 3061 | YJR029W | YJR029W SGDID:S000003790, Chr X from 478337-479637,479639-483605, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 3062 | YJR030C | YJR030C SGDID:S000003791, Chr X from 486189-483952, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; expression repressed in carbon limited vs carbon replete chemostat cultures; YJR030C is a non-essential gene" |
| 3063 | YJR031C | GEA1 SGDID:S000003792, Chr X from 490805-486579, reverse complement, Verified ORF, "Guanine nucleotide exchange factor for ADP ribosylation factors (ARFs), involved in vesicular transport between the Golgi and ER, Golgi organization, and actin cytoskeleton organization; similar to but not functionally redundant with Gea2p" |
| 3064 | YJR032W | CPR7 SGDID:S000003793, Chr X from 491074-492255, Verified ORF, "Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity" |
| 3065 | YJR033C | RAV1 SGDID:S000003794, Chr X from 496444-492371, reverse complement, Verified ORF, "Subunit of the RAVE complex (Rav1p, Rav2p, Skp1p), which promotes assembly of the V-ATPase holoenzyme; required for transport between the early and late endosome/PVC and for localization of TGN membrane proteins; potential Cdc28p substrate" |
| 3066 | YJR034W | PET191 SGDID:S000003795, Chr X from 496676-497002, Verified ORF, "Protein required for assembly of cytochrome c oxidase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3067 | YJR035W | RAD26 SGDID:S000003796, Chr X from 497348-500605, Verified ORF, "Protein involved in transcription-coupled repair nucleotide excision repair of UV-induced DNA lesions; homolog of human CSB protein" |
| 3068 | YJR036C | HUL4 SGDID:S000003797, Chr X from 503384-500706, reverse complement, Verified ORF, "Protein with similarity to hect domain E3 ubiquitin-protein ligases, not essential for viability" |
| 3069 | YJR039W | YJR039W SGDID:S000003800, Chr X from 503929-507294, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3070 | YJR040W | GEF1 SGDID:S000003801, Chr X from 507739-510078, Verified ORF, "Chloride channel localized to late- or post-Golgi vesicles, involved in iron metabolism; highly homologous to voltage-gated chloride channels in vertebrates" |
| 3071 | YJR041C | URB2 SGDID:S000003802, Chr X from 513756-510232, reverse complement, Verified ORF, "Nucleolar protein required for normal metabolism of the rRNA primary transcript, proposed to be involved in ribosome biogenesis" |
| 3072 | YJR042W | NUP85 SGDID:S000003803, Chr X from 514048-516282, Verified ORF, "Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), required for assembly of the subcomplex and also for formation of the nucleocytoplasmic Gsp1p concentration gradient that plays a role in nuclear trafficking" |
| 3073 | YJR043C | POL32 SGDID:S000003804, Chr X from 517506-516454, reverse complement, Verified ORF, "Third subunit of DNA polymerase delta, involved in chromosomal DNA replication; required for error-prone DNA synthesis in the presence of DNA damage and processivity; interacts with Hys2p, PCNA (Pol30p), and Pol1p" |
| 3074 | YJR044C | VPS55 SGDID:S000003805, Chr X from 519178-518756, reverse complement, Verified ORF, "Late endosomal protein involved in late endosome to vacuole trafficking; functional homolog of human obesity receptor gene-related protein (OB-RGRP)" |
| 3075 | YJR045C | SSC1 SGDID:S000003806, Chr X from 521595-519631, reverse complement, Verified ORF, "Mitochondrial matrix ATPase, subunit of the presequence translocase-associated protein import motor (PAM) and of SceI endonuclease; involved in protein folding and translocation into the matrix; phosphorylated; member of HSP70 family" |
| 3076 | YJR046W | TAH11 SGDID:S000003807, Chr X from 522041-523855, Verified ORF, "DNA replication licensing factor, required for pre-replication complex assembly" |
| 3077 | YJR047C | ANB1 SGDID:S000003808, Chr X from 525374-524901, reverse complement, Verified ORF, "Translation initiation factor eIF-5A, promotes formation of the first peptide bond; similar to and functionally redundant with Hyp2p; undergoes an essential hypusination modification; expressed under anaerobic conditions" |
| 3078 | YJR048W | CYC1 SGDID:S000003809, Chr X from 526328-526657, Verified ORF, "Cytochrome c, isoform 1; electron carrier of the mitochondrial intermembrane space that transfers electrons from ubiquinone-cytochrome c oxidoreductase to cytochrome c oxidase during cellular respiration" |
| 3079 | YJR049C | UTR1 SGDID:S000003810, Chr X from 528469-526877, reverse complement, Verified ORF, "ATP-NADH kinase; phosphorylates both NAD and NADH; active as a hexamer; enhances the activity of ferric reductase (Fre1p)" |
| 3080 | YJR050W | ISY1 SGDID:S000003811, Chr X from 528690-529397, Verified ORF, "Component of the spliceosome complex involved in pre-mRNA splicing, auxiliary splicing factor that may modulate Syf1p activity and help optimize splicing; isy1 syf2 double mutation activates the spindle checkpoint, causing cell cycle arrest" |
| 3081 | YJR051W | OSM1 SGDID:S000003812, Chr X from 529854-531359, Verified ORF, "Fumarate reductase, catalyzes the reduction of fumarate to succinate, required for the reoxidation of intracellular NADH under anaerobic conditions; mutations cause osmotic sensitivity" |
| 3082 | YJR052W | RAD7 SGDID:S000003813, Chr X from 532055-533752, Verified ORF, "Protein that recognizes and binds damaged DNA in an ATP-dependent manner (with Rad16p) during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex" |
| 3083 | YJR053W | BFA1 SGDID:S000003814, Chr X from 534020-535744, Verified ORF, "Component of the GTPase-activating Bfa1p-Bub2p complex involved in multiple cell cycle checkpoint pathways that control exit from mitosis" |
| 3084 | YJR054W | YJR054W SGDID:S000003815, Chr X from 536049-537542, Uncharacterized ORF, "Vacuolar protein of unknown function; potential Cdc28p substrate" |
| 3085 | YJR055W | HIT1 SGDID:S000003816, Chr X from 538765-539259, Verified ORF, "Protein of unknown function, required for growth at high temperature" |
| 3086 | YJR056C | YJR056C SGDID:S000003817, Chr X from 542495-541785, reverse complement, Uncharacterized ORF, "Hypothetical protein" |
| 3087 | YJR057W | CDC8 SGDID:S000003818, Chr X from 544055-544705, Verified ORF, "Thymidylate and uridylate kinase, functions in de novo biosynthesis of pyrimidine deoxyribonucleotides; converts dTMP to dTDP and dUMP to dUTP; essential for mitotic and meiotic DNA replication; homologous to S. pombe Tmp1p" |
| 3088 | YJR058C | APS2 SGDID:S000003819, Chr X from 545168-544725, reverse complement, Verified ORF, "Small subunit of the clathrin-associated adaptor complex AP-2, which is involved in protein sorting at the plasma membrane; related to the sigma subunit of the mammalian plasma membrane clathrin-associated protein (AP-2) complex" |
| 3089 | YJR059W | PTK2 SGDID:S000003820, Chr X from 545780-548236, Verified ORF, "Putative serine/threonine protein kinase involved in regulation of ion transport across plasma membrane; enhances spermine uptake" |
| 3090 | YJR060W | CBF1 SGDID:S000003821, Chr X from 548752-549807, Verified ORF, "Helix-loop-helix protein that binds the motif CACRTG, which is present at several sites including MET gene promoters and centromere DNA element I (CDEI); required for nucleosome positioning at this motif; targets Isw1p to DNA" |
| 3091 | YJR061W | YJR061W SGDID:S000003822, Chr X from 550504-553311, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene with similarity to Mnn4, a putative membrane protein involved in glycosylation; transcription repressed by Rm101p" |
| 3092 | YJR062C | NTA1 SGDID:S000003823, Chr X from 554842-553469, reverse complement, Verified ORF, "Amidase, removes the amide group from N-terminal asparagine and glutamine residues to generate proteins with N-terminal aspartate and glutamate residues that are targets of ubiquitin-mediated degradation" |
| 3093 | YJR063W | RPA12 SGDID:S000003824, Chr X from 555188-555565, Verified ORF, "RNA polymerase I subunit A12.2; contains two zinc binding domains, and the N terminal domain is responsible for anchoring to the RNA pol I complex" |
| 3094 | YJR064W | CCT5 SGDID:S000003825, Chr X from 555907-557595, Verified ORF, "Subunit of the cytosolic chaperonin Cct ring complex, related to Tcp1p, required for the assembly of actin and tubulins in vivo" |
| 3095 | YJR065C | ARP3 SGDID:S000003826, Chr X from 559151-557802, reverse complement, Verified ORF, "Essential component of the Arp2/3 complex, which is a highly conserved actin nucleation center required for the motility and integrity of actin patches; involved in endocytosis and membrane growth and polarity" |
| 3096 | YJR066W | TOR1 SGDID:S000003827, Chr X from 559409-566821, Verified ORF, "PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that controls growth in response to nutrients by regulating translation, transcription, ribosome biogenesis, nutrient transport and autophagy; involved in meiosis" |
| 3097 | YJR067C | YAE1 SGDID:S000003828, Chr X from 567437-567012, reverse complement, Verified ORF, "Essential protein of unknown function" |
| 3098 | YJR068W | RFC2 SGDID:S000003829, Chr X from 567636-568697, Verified ORF, "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon" |
| 3099 | YJR069C | HAM1 SGDID:S000003830, Chr X from 569392-568799, reverse complement, Verified ORF, "Conserved protein with deoxyribonucleoside triphosphate pyrophosphohydrolase activity, mediates exclusion of noncanonical purines from deoxyribonucleoside triphosphate pools; mutant is sensitive to the base analog 6-N-hydroxylaminopurine" |
| 3100 | YJR070C | LIA1 SGDID:S000003831, Chr X from 570591-569614, reverse complement, Verified ORF, "Deoxyhypusine hydroxylase, a HEAT-repeat containing metalloenzyme that catalyses hypusine formation; binds to and is required for the modification of Hyp2p (eIF5A); complements S. pombe mmd1 mutants defective in mitochondrial positioning" |
| 3101 | YJR072C | NPA3 SGDID:S000003833, Chr X from 572117-570960, reverse complement, Verified ORF, "Essential, conserved, cytoplasmic ATPase; phosphorylated by the Pcl1p-Pho85p kinase complex" |
| 3102 | YJR073C | OPI3 SGDID:S000003834, Chr X from 572928-572308, reverse complement, Verified ORF, "Phospholipid methyltransferase (methylene-fatty-acyl-phospholipid synthase), catalyzes the last two steps in phosphatidylcholine biosynthesis" |
| 3103 | YJR074W | MOG1 SGDID:S000003835, Chr X from 573088-573744, Verified ORF, "Conserved nuclear protein that interacts with GTP-Gsp1p, which is a Ran homolog of the Ras GTPase family, and stimulates nucleotide release, involved in nuclear protein import, nucleotide release is inhibited by Yrb1p" |
| 3104 | YJR075W | HOC1 SGDID:S000003836, Chr X from 573974-575164, Verified ORF, "Alpha-1,6-mannosyltransferase involved in cell wall mannan biosynthesis; subunit of a Golgi-localized complex that also contains Anp1p, Mnn9p, Mnn11p, and Mnn10p; identified as a suppressor of a cell lysis sensitive pkc1-371 allele" |
| 3105 | YJR076C | CDC11 SGDID:S000003837, Chr X from 576594-575347, reverse complement, Verified ORF, "Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM" |
| 3106 | YJR077C | MIR1 SGDID:S000003838, Chr X from 578183-577248, reverse complement, Verified ORF, "Mitochondrial phosphate carrier, imports inorganic phosphate into mitochondria; functionally redundant with Pic2p but more abundant than Pic2p under normal conditions; phosphorylated" |
| 3107 | YJR078W | BNA2 SGDID:S000003839, Chr X from 578853-580214, Verified ORF, "Putative tryptophan 2,3-dioxygenase or indoleamine 2,3-dioxygenase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p and Aft2p" |
| 3108 | YJR079W | YJR079W SGDID:S000003840, Chr X from 580198-580340,581046-581232, Uncharacterized ORF, "Putative protein of unknown function; mutation results in impaired mitochondrial respiration" |
| 3109 | YJR080C | YJR080C SGDID:S000003841, Chr X from 581609-580425, reverse complement, Uncharacterized ORF, "Protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss and reduced growth rate in minimal glycerol media" |
| 3110 | YJR082C | EAF6 SGDID:S000003842, Chr X from 582248-581907, reverse complement, Verified ORF, "Subunit of the NuA4 acetyltransferase complex that acetylates histone H4 and NuA3 acetyltransferase complex that acetylates histone H3" |
| 3111 | YJR083C | ACF4 SGDID:S000003843, Chr X from 583530-582601, reverse complement, Verified ORF, "Protein of unknown function, computational analysis of large-scale protein-protein interaction data suggests a possible role in actin cytoskeleton organization; potential Cdc28p substrate" |
| 3112 | YJR084W | CSN12 SGDID:S000003844, Chr X from 583726-584997, Verified ORF, "Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling" |
| 3113 | YJR085C | YJR085C SGDID:S000003845, Chr X from 585430-585113, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3114 | YJR086W | STE18 SGDID:S000003846, Chr X from 586061-586393, Verified ORF, "G protein gamma subunit, forms a dimer with Ste4p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste4p to dampen signaling; C-terminus is palmitoylated and farnesylated, which are required for normal signaling" |
| 3115 | YJR088C | YJR088C SGDID:S000003848, Chr X from 587366-586488, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum" |
| 3116 | YJR089W | BIR1 SGDID:S000003849, Chr X from 587711-590575, Verified ORF, "Essential chromosomal passenger protein involved in coordinating cell cycle events for proper chromosome segregation; C-terminal region binds Sli15p, and the middle region, upon phosphorylation, localizes Cbf2p to the spindle at anaphase" |
| 3117 | YJR090C | GRR1 SGDID:S000003850, Chr X from 594320-590865, reverse complement, Verified ORF, "F-box protein component of the SCF ubiquitin-ligase complex; involved in carbon catabolite repression, glucose-dependent divalent cation transport, high-affinity glucose transport, morphogenesis, and sulfite detoxification" |
| 3118 | YJR091C | JSN1 SGDID:S000003851, Chr X from 598329-595054, reverse complement, Verified ORF, "Member of the Puf family of RNA-binding proteins, interacts with mRNAs encoding membrane-associated proteins; overexpression suppresses a tub2-150 mutation and causes increased sensitivity to benomyl in wild-type cells" |
| 3119 | YJR092W | BUD4 SGDID:S000003852, Chr X from 598728-603071, Verified ORF, "Protein involved in bud-site selection and required for axial budding pattern; localizes with septins to bud neck in mitosis and may constitute an axial landmark for next round of budding; potential Cdc28p substrate" |
| 3120 | YJR093C | FIP1 SGDID:S000003853, Chr X from 604196-603213, reverse complement, Verified ORF, "Subunit of cleavage polyadenylation factor (CPF), interacts directly with poly(A) polymerase (Pap1p) to regulate its activity" |
| 3121 | YJR094C | IME1 SGDID:S000003854, Chr X from 605644-604562, reverse complement, Verified ORF, "Master regulator of meiosis that is active only during meiotic events, activates transcription of early meiotic genes through interaction with Ume6p, degraded by the 26S proteasome following phosphorylation by Ime2p" |
| 3122 | YJR094W-A | RPL43B SGDID:S000003855, Chr X from 608298-608299,608575-608851, Verified ORF, "Protein component of the large (60S) ribosomal subunit, identical to Rpl43Ap and has similarity to rat L37a ribosomal protein" |
| 3123 | YJR095W | SFC1 SGDID:S000003856, Chr X from 609766-610734, Verified ORF, "Mitochondrial succinate-fumarate transporter, transports succinate into and fumarate out of the mitochondrion; required for ethanol and acetate utilization" |
| 3124 | YJR096W | YJR096W SGDID:S000003857, Chr X from 611188-612036, Verified ORF, "Putative xylose and arabinose reductase; member of the aldo-keto reductase (AKR) family; GFP-fusion protein is induced in response to the DNA-damaging agent MMS" |
| 3125 | YJR097W | JJJ3 SGDID:S000003858, Chr X from 612406-612924, Verified ORF, "Protein of unknown function, contains a J-domain, which is a region with homology to the E. coli DnaJ protein" |
| 3126 | YJR098C | YJR098C SGDID:S000003859, Chr X from 615146-613179, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3127 | YJR099W | YUH1 SGDID:S000003860, Chr X from 615566-616276, Verified ORF, "Ubiquitin C-terminal hydrolase that cleaves ubiquitin-protein fusions to generate monomeric ubiquitin; hydrolyzes the peptide bond at the C-terminus of ubiquitin; also the major processing enzyme for the ubiquitin-like protein Rub1p" |
| 3128 | YJR100C | YJR100C SGDID:S000003861, Chr X from 617324-616341, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss (petite formation); similar to murine NOR1" |
| 3129 | YJR101W | RSM26 SGDID:S000003862, Chr X from 618224-619024, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 3130 | YJR102C | VPS25 SGDID:S000003863, Chr X from 619755-619147, reverse complement, Verified ORF, "Component of the ESCRT-II complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome" |
| 3131 | YJR103W | URA8 SGDID:S000003864, Chr X from 620744-622438, Verified ORF, "Minor CTP synthase isozyme (see also URA7), catalyzes the ATP-dependent transfer of the amide nitrogen from glutamine to UTP, forming CTP, the final step in de novo biosynthesis of pyrimidines; involved in phospholipid biosynthesis" |
| 3132 | YJR104C | SOD1 SGDID:S000003865, Chr X from 623003-622539, reverse complement, Verified ORF, "Cytosolic superoxide dismutase; some mutations are analogous to those that cause ALS (amyotrophic lateral sclerosis) in humans" |
| 3133 | YJR105W | ADO1 SGDID:S000003866, Chr X from 623570-624592, Verified ORF, "Adenosine kinase, required for the utilization of S-adenosylmethionine (AdoMet); may be involved in recycling adenosine produced through the methyl cycle" |
| 3134 | YJR106W | ECM27 SGDID:S000003867, Chr X from 624827-627004, Verified ORF, "Non-essential protein of unknown function" |
| 3135 | YJR107W | YJR107W SGDID:S000003868, Chr X from 627330-628316, Uncharacterized ORF, "Putative protein of unknown function; has sequence or structural similarity to lipases" |
| 3136 | YJR108W | ABM1 SGDID:S000003869, Chr X from 628703-629074, Verified ORF, "Protein of unknown function, required for normal microtubule organization" |
| 3137 | YJR109C | CPA2 SGDID:S000003870, Chr X from 632932-629576, reverse complement, Verified ORF, "Large subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor" |
| 3138 | YJR110W | YMR1 SGDID:S000003871, Chr X from 633606-635672, Verified ORF, "Phosphatidylinositol 3-phosphate [PI(3)P] phosphatase, regulates the localization and levels of PI(3)P; involved in cytoplasm to vacuole (CVT) transport; has similarity to the conserved myotubularin dual specificity phosphatase family" |
| 3139 | YJR111C | YJR111C SGDID:S000003872, Chr X from 636697-635846, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondria" |
| 3140 | YJR112W | NNF1 SGDID:S000003873, Chr X from 637021-637626, Verified ORF, "Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; required for accurate chromosome segregation" |
| 3141 | YJR112W-A | YJR112W-A SGDID:S000028513, Chr X from 637781-637800,637850-638159, Uncharacterized ORF, "Putative protein of unknown function; identified based on homology to Ashbya gossypii" |
| 3142 | YJR113C | RSM7 SGDID:S000003874, Chr X from 638966-638223, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S7 ribosomal protein" |
| 3143 | YJR115W | YJR115W SGDID:S000003876, Chr X from 639933-640442, Uncharacterized ORF, "Putative protein of unknown function" |
| 3144 | YJR116W | YJR116W SGDID:S000003877, Chr X from 640816-641655, Uncharacterized ORF, "Putative protein of unknown function" |
| 3145 | YJR117W | STE24 SGDID:S000003878, Chr X from 641998-643359, Verified ORF, "Highly conserved zinc metalloprotease that functions in two steps of a-factor maturation, C-terminal CAAX proteolysis and the first step of N-terminal proteolytic processing; contains multiple transmembrane spans" |
| 3146 | YJR118C | ILM1 SGDID:S000003879, Chr X from 644092-643481, reverse complement, Verified ORF, "Protein of unknown function; may be involved in mitochondrial DNA maintenance; required for slowed DNA synthesis-induced filamentous growth" |
| 3147 | YJR119C | JHD2 SGDID:S000003880, Chr X from 646481-644295, reverse complement, Verified ORF, "JmjC domain family histone demethylase specific for H3-K4 (lysine at position 4 of the histone H3 protein); removes methyl groups specifically added by Set1p methyltransferase" |
| 3148 | YJR120W | YJR120W SGDID:S000003881, Chr X from 647117-647467, Verified ORF, "Protein of unknown function; essential for growth under anaerobic conditions; mutation causes decreased expression of ATP2, impaired respiration, defective sterol uptake, and altered levels/localization of ABC transporters Aus1p and Pdr11p" |
| 3149 | YJR121W | ATP2 SGDID:S000003882, Chr X from 647598-649133, Verified ORF, "Beta subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" |
| 3150 | YJR122W | IBA57 SGDID:S000003883, Chr X from 649767-651260, Verified ORF, "Mitochondrial matrix protein involved in the incorporation of iron-sulfur clusters into mitochondrial aconitase-type proteins; activates the radical-SAM family members Bio2p and Lip5p; interacts with Ccr4p in the two-hybrid system" |
| 3151 | YJR123W | RPS5 SGDID:S000003884, Chr X from 651892-652569, Verified ORF, "Protein component of the small (40S) ribosomal subunit, the least basic of the non-acidic ribosomal proteins; phosphorylated in vivo; essential for viability; has similarity to E. coli S7 and rat S5 ribosomal proteins" |
| 3152 | YJR124C | YJR124C SGDID:S000003885, Chr X from 654229-652883, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; expression induced under calcium shortage" |
| 3153 | YJR125C | ENT3 SGDID:S000003886, Chr X from 655954-654728, reverse complement, Verified ORF, "Protein containing an N-terminal epsin-like domain involved in clathrin recruitment and traffic between the Golgi and endosomes; associates with the clathrin adaptor Gga2p" |
| 3154 | YJR126C | VPS70 SGDID:S000003887, Chr X from 658680-656245, reverse complement, Verified ORF, "Protein of unknown function involved in vacuolar protein sorting" |
| 3155 | YJR127C | RSF2 SGDID:S000003888, Chr X from 663050-658908, reverse complement, Verified ORF, "Zinc-finger protein involved in transcriptional control of both nuclear and mitochondrial genes, many of which specify products required for glycerol-based growth, respiration, and other functions" |
| 3156 | YJR129C | YJR129C SGDID:S000003890, Chr X from 665010-663991, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; predicted S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 3157 | YJR130C | STR2 SGDID:S000003891, Chr X from 667128-665209, reverse complement, Verified ORF, "Cystathionine gamma-synthase, converts cysteine into cystathionine" |
| 3158 | YJR131W | MNS1 SGDID:S000003892, Chr X from 667635-669284, Verified ORF, "Alpha-1,2-mannosidase involved in ER quality control; catalyzes the removal of one mannose residue from Man9GlcNAc to produce a single isomer of Man8GlcNAc in N-linked oligosaccharide biosynthesis; integral to ER membrane" |
| 3159 | YJR132W | NMD5 SGDID:S000003893, Chr X from 669513-672659, Verified ORF, "Karyopherin, a carrier protein involved in nuclear import of proteins; importin beta homolog" |
| 3160 | YJR133W | XPT1 SGDID:S000003894, Chr X from 672982-673611, Verified ORF, "Xanthine-guanine phosphoribosyl transferase, required for xanthine utilization and for optimal utilization of guanine" |
| 3161 | YJR134C | SGM1 SGDID:S000003895, Chr X from 675843-673720, reverse complement, Verified ORF, "Protein of unknown function, required for wild-type growth rate on galactose and mannose; localizes to COPI coated vesicles and the Golgi apparatus" |
| 3162 | YJR135C | MCM22 SGDID:S000003896, Chr X from 676769-676050, reverse complement, Verified ORF, "Protein involved in minichromosome maintenance; component of the kinetochore; binds to centromeric DNA in a Ctf19p-dependent manner" |
| 3163 | YJR135W-A | TIM8 SGDID:S000007348, Chr X from 676962-677225, Verified ORF, "Mitochondrial intermembrane space protein mediating import and insertion of polytopic inner membrane proteins; homolog of human DDP1 (deafness dystonia peptide 1) which is mutated in the X-linked Mohr-Tranebjaerg syndrome" |
| 3164 | YJR136C | YJR136C SGDID:S000003897, Chr X from 678697-677432, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; may interact with mitochondrial ribosomal protein Rsm23p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 3165 | YJR137C | ECM17 SGDID:S000003898, Chr X from 683276-678948, reverse complement, Verified ORF, "Sulfite reductase beta subunit, involved in amino acid biosynthesis, transcription repressed by methionine" |
| 3166 | YJR138W | IML1 SGDID:S000003899, Chr X from 684558-689312, Verified ORF, "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the vacuolar membrane" |
| 3167 | YJR139C | HOM6 SGDID:S000003900, Chr X from 690515-689436, reverse complement, Verified ORF, "Homoserine dehydrogenase (L-homoserine:NADP oxidoreductase), dimeric enzyme that catalyzes the third step in the common pathway for methionine and threonine biosynthesis; enzyme has nucleotide-binding, dimerization and catalytic regions" |
| 3168 | YJR140C | HIR3 SGDID:S000003901, Chr X from 695687-690741, reverse complement, Verified ORF, "Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; involved in position-dependent gene silencing and nucleosome reassembly" |
| 3169 | YJR141W | YJR141W SGDID:S000003902, Chr X from 695897-696940, Uncharacterized ORF, "Putative protein of unknown function; may be involved in mRNA processing; YJR141W is an essential gene" |
| 3170 | YJR142W | YJR142W SGDID:S000003903, Chr X from 697132-698160, Uncharacterized ORF, "Putative protein of unknown function; GST fusion protein is a Dbf2-Mob1 phosphoylation target in a proteome chip analysis; synthetic lethal with PH085 deletion; plays a role in restricting Ty1 transposition" |
| 3171 | YJR143C | PMT4 SGDID:S000003904, Chr X from 700605-698317, reverse complement, Verified ORF, "Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; appears to form homodimers in vivo and does not complex with other Pmt proteins; target for new antifungals" |
| 3172 | YJR144W | MGM101 SGDID:S000003905, Chr X from 700873-701682, Verified ORF, "Protein involved in mitochondrial genome maintenance; component of the mitochondrial nucleoid, required for the repair of oxidative mtDNA damage" |
| 3173 | YJR145C | RPS4A SGDID:S000003906, Chr X from 703059-703046,702789-702018, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; mutation affects 20S pre-rRNA processing; identical to Rps4Bp and has similarity to rat S4 ribosomal protein" |
| 3174 | YJR147W | HMS2 SGDID:S000003908, Chr X from 704187-705263, Verified ORF, "Protein with similarity to heat shock transcription factors; overexpression suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant" |
| 3175 | YJR148W | BAT2 SGDID:S000003909, Chr X from 705735-706865, Verified ORF, "Cytosolic branched-chain amino acid aminotransferase, homolog of murine ECA39; highly expressed during stationary phase and repressed during logarithmic phase" |
| 3176 | YJR149W | YJR149W SGDID:S000003910, Chr X from 707151-708365, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 3177 | YJR150C | DAN1 SGDID:S000003911, Chr X from 709698-708802, reverse complement, Verified ORF, "Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth" |
| 3178 | YJR151C | DAN4 SGDID:S000003912, Chr X from 715731-712246, reverse complement, Verified ORF, "Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth" |
| 3179 | YJR151W-A | YJR151W-A SGDID:S000028557, Chr X from 717571-717621, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 3180 | YJR152W | DAL5 SGDID:S000003913, Chr X from 719657-721288, Verified ORF, "Allantoin permease; ureidosuccinate permease; expression is constitutive but sensitive to nitrogen catabolite repression" |
| 3181 | YJR153W | PGU1 SGDID:S000003914, Chr X from 722806-723891, Verified ORF, "Endo-polygalacturonase, pectolytic enzyme that hydrolyzes the alpha-1,4-glycosidic bonds in the rhamnogalacturonan chains in pectins" |
| 3182 | YJR154W | YJR154W SGDID:S000003915, Chr X from 725775-726815, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 3183 | YJR155W | AAD10 SGDID:S000003916, Chr X from 727396-728262, Verified ORF, "Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role" |
| 3184 | YJR156C | THI11 SGDID:S000003917, Chr X from 729587-728565, reverse complement, Verified ORF, "Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13" |
| 3185 | YJR158W | HXT16 SGDID:S000003919, Chr X from 732431-734134, Verified ORF, "Protein of unknown function with similarity to hexose transporter family members, expression is repressed by high levels of glucose" |
| 3186 | YJR159W | SOR1 SGDID:S000003920, Chr X from 736035-737108, Verified ORF, "Sorbitol dehydrogenase; expression is induced in the presence of sorbitol" |
| 3187 | YJR160C | MPH3 SGDID:S000003921, Chr X from 739807-737999, reverse complement, Verified ORF, "Alpha-glucoside permease, transports maltose, maltotriose, alpha-methylglucoside, and turanose; identical to Mph2p; encoded in a subtelomeric position in a region likely to have undergone duplication" |
| 3188 | YJR161C | COS5 SGDID:S000003922, Chr X from 743990-742839, reverse complement, Verified ORF, "Protein of unknown function, member the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" |
| 3189 | YKL001C | MET14 SGDID:S000001484, Chr XI from 439028-438420, reverse complement, Verified ORF, "Adenylylsulfate kinase, required for sulfate assimilation and involved in methionine metabolism" |
| 3190 | YKL002W | DID4 SGDID:S000001485, Chr XI from 437421-437480,437549-438187, Verified ORF, "Class E Vps protein of the ESCRT-III complex, required for sorting of integral membrane proteins into lumenal vesicles of multivesicular bodies, and for delivery of newly synthesized vacuolar enzymes to the vacuole, involved in endocytosis" |
| 3191 | YKL003C | MRP17 SGDID:S000001486, Chr XI from 437135-436740, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the small subunit; MRP17 exhibits genetic interactions with PET122, encoding a COX3-specific translational activator" |
| 3192 | YKL004W | AUR1 SGDID:S000001487, Chr XI from 435223-436428, Verified ORF, "Phosphatidylinositol:ceramide phosphoinositol transferase (IPC synthase), required for sphingolipid synthesis; can mutate to confer aureobasidin A resistance" |
| 3193 | YKL005C | BYE1 SGDID:S000001488, Chr XI from 434520-432736, reverse complement, Verified ORF, "Negative regulator of transcription elongation, contains a TFIIS-like domain and a PHD finger, multicopy suppressor of temperature-sensitive ess1 mutations, probably binds RNA polymerase II large subunit" |
| 3194 | YKL006C-A | SFT1 SGDID:S000002101, Chr XI from 430275-430240,430098-429841, reverse complement, Verified ORF, "Intra-Golgi v-SNARE, required for transport of proteins between an early and a later Golgi compartment" |
| 3195 | YKL006W | RPL14A SGDID:S000001489, Chr XI from 431549-431677,432076-432363, Verified ORF, "N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl14Bp and has similarity to rat L14 ribosomal protein; rpl14a csh5 double null mutant exhibits synthetic slow growth" |
| 3196 | YKL007W | CAP1 SGDID:S000001490, Chr XI from 428945-429751, Verified ORF, "Alpha subunit of the capping protein (CP) heterodimer (Cap1p and Cap2p) which binds to the barbed ends of actin filaments preventing further polymerization; localized predominantly to cortical actin patches" |
| 3197 | YKL008C | LAC1 SGDID:S000001491, Chr XI from 428194-426938, reverse complement, Verified ORF, "Ceramide synthase component, involved in synthesis of ceramide from C26(acyl)-coenzyme A and dihydrosphingosine or phytosphingosine, functionally equivalent to Lag1p" |
| 3198 | YKL009W | MRT4 SGDID:S000001492, Chr XI from 425885-426595, Verified ORF, "Protein involved in mRNA turnover and ribosome assembly, localizes to the nucleolus" |
| 3199 | YKL010C | UFD4 SGDID:S000001493, Chr XI from 425518-421067, reverse complement, Verified ORF, "Ubiquitin-protein ligase (E3) that interacts with Rpt4p and Rpt6p, two subunits of the 19S particle of the 26S proteasome; cytoplasmic E3 involved in the degradation of ubiquitin fusion proteins" |
| 3200 | YKL011C | CCE1 SGDID:S000001494, Chr XI from 420859-419798, reverse complement, Verified ORF, "Mitochondrial cruciform cutting endonuclease, cleaves Holliday junctions formed during recombination of mitochondrial DNA" |
| 3201 | YKL012W | PRP40 SGDID:S000001495, Chr XI from 417953-419704, Verified ORF, "U1 snRNP protein involved in splicing, interacts with the branchpoint-binding protein during the formation of the second commitment complex" |
| 3202 | YKL013C | ARC19 SGDID:S000001496, Chr XI from 417666-417151, reverse complement, Verified ORF, "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches" |
| 3203 | YKL014C | URB1 SGDID:S000001497, Chr XI from 416556-411262, reverse complement, Verified ORF, "Nucleolar protein required for the normal accumulation of 25S and 5.8S rRNAs, associated with the 27SA2 pre-ribosomal particle; proposed to be involved in the biogenesis of the 60S ribosomal subunit" |
| 3204 | YKL015W | PUT3 SGDID:S000001498, Chr XI from 408187-411126, Verified ORF, "Transcriptional activator of proline utilization genes, constitutively binds PUT1 and PUT2 promoter sequences and undergoes a conformational change to form the active state; has a Zn(2)-Cys(6) binuclear cluster domain" |
| 3205 | YKL016C | ATP7 SGDID:S000001499, Chr XI from 407632-407108, reverse complement, Verified ORF, "Subunit d of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" |
| 3206 | YKL017C | HCS1 SGDID:S000001500, Chr XI from 406884-404833, reverse complement, Verified ORF, "Hexameric DNA polymerase alpha-associated DNA helicase A involved in lagging strand DNA synthesis; contains single-stranded DNA stimulated ATPase and dATPase activities; replication protein A stimulates helicase and ATPase activities" |
| 3207 | YKL018C-A | YKL018C-A SGDID:S000007615, Chr XI from 403522-403223, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by homology; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 3208 | YKL018W | SWD2 SGDID:S000001501, Chr XI from 403745-404734, Verified ORF, "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lys 4 and is involved in telomeric silencing; subunit of CPF (cleavage and polyadenylation factor), a complex involved in RNAP II transcription termination" |
| 3209 | YKL019W | RAM2 SGDID:S000001502, Chr XI from 402211-403161, Verified ORF, "Alpha subunit of both the farnesyltransferase and type I geranylgeranyltransferase that catalyze prenylation of proteins containing a CAAX consensus motif; essential protein required for membrane localization of Ras proteins and a-factor" |
| 3210 | YKL020C | SPT23 SGDID:S000001503, Chr XI from 401723-398475, reverse complement, Verified ORF, "ER membrane protein involved in regulation of OLE1 transcription, acts with homolog Mga2p; inactive ER form dimerizes and one subunit is then activated by ubiquitin/proteasome-dependent processing followed by nuclear targeting" |
| 3211 | YKL021C | MAK11 SGDID:S000001504, Chr XI from 398393-396987, reverse complement, Verified ORF, "Protein involved in an early, nucleolar step of 60S ribosomal subunit biogenesis; essential for cell growth and replication of killer M1 dsRNA virus; contains four beta-transducin repeats" |
| 3212 | YKL022C | CDC16 SGDID:S000001505, Chr XI from 396891-394369, reverse complement, Verified ORF, "Subunit of the anaphase-promoting complex/cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; required for sporulation" |
| 3213 | YKL023C-A | YKL023C-A SGDID:S000113559, Chr XI from 393016-392789, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 3214 | YKL023W | YKL023W SGDID:S000001506, Chr XI from 393364-394197, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 3215 | YKL024C | URA6 SGDID:S000001507, Chr XI from 392783-392169, reverse complement, Verified ORF, "Uridylate kinase, catalyzes the seventh enzymatic step in the de novo biosynthesis of pyrimidines, converting uridine monophosphate (UMP) into uridine-5'-diphosphate (UDP)" |
| 3216 | YKL025C | PAN3 SGDID:S000001508, Chr XI from 391922-389883, reverse complement, Verified ORF, "Essential subunit of the Pan2p-Pan3p poly(A)-ribonuclease complex, which acts to control poly(A) tail length and regulate the stoichiometry and activity of postreplication repair complexes" |
| 3217 | YKL026C | GPX1 SGDID:S000001509, Chr XI from 389526-389023, reverse complement, Verified ORF, "Phospholipid hydroperoxide glutathione peroxidase induced by glucose starvation that protects cells from phospholipid hydroperoxides and nonphospholipid peroxides during oxidative stress" |
| 3218 | YKL027W | YKL027W SGDID:S000001510, Chr XI from 387205-388548, Verified ORF, "Protein of unknown function, localized to the mitochondrial outer membrane" |
| 3219 | YKL028W | TFA1 SGDID:S000001511, Chr XI from 385401-386849, Verified ORF, "TFIIE large subunit, involved in recruitment of RNA polymerase II to the promoter, activation of TFIIH, and promoter opening" |
| 3220 | YKL029C | MAE1 SGDID:S000001512, Chr XI from 384368-382359, reverse complement, Verified ORF, "Mitochondrial malic enzyme, catalyzes the oxidative decarboxylation of malate to pyruvate, which is a key intermediate in sugar metabolism and a precursor for synthesis of several amino acids" |
| 3221 | YKL032C | IXR1 SGDID:S000001515, Chr XI from 381501-379708, reverse complement, Verified ORF, "Protein that binds DNA containing intrastrand cross-links formed by cisplatin, contains two HMG (high mobility group box) domains, which confer the ability to bend cisplatin-modified DNA; mediates aerobic transcriptional repression of COX5b" |
| 3222 | YKL033W | YKL033W SGDID:S000001516, Chr XI from 375099-378215, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YKL033W is an essential gene" |
| 3223 | YKL033W-A | YKL033W-A SGDID:S000007242, Chr XI from 374148-374858, Uncharacterized ORF, "Putative protein of unknown function; similar to uncharacterized proteins from other fungi" |
| 3224 | YKL034W | TUL1 SGDID:S000001517, Chr XI from 371472-373748, Verified ORF, "Golgi-localized RING-finger ubiquitin ligase (E3), involved in ubiquitinating and sorting membrane proteins that contain polar transmembrane domains to multivesicular bodies for delivery to the vacuole for quality control purposes" |
| 3225 | YKL035W | UGP1 SGDID:S000001518, Chr XI from 369534-371033, Verified ORF, "UDP-glucose pyrophosphorylase (UGPase), catalyses the reversible formation of UDP-Glc from glucose 1-phosphate and UTP, involved in a wide variety of metabolic pathways, expression modulated by Pho85p through Pho4p" |
| 3226 | YKL037W | YKL037W SGDID:S000001520, Chr XI from 369008-369364, Uncharacterized ORF, "Putative protein of unknown function; null mutant is viable and displays increased frequency of mitochondrial genome loss (petite formation)" |
| 3227 | YKL038W | RGT1 SGDID:S000001521, Chr XI from 365248-368760, Verified ORF, "Glucose-responsive transcription factor that regulates expression of several glucose transporter (HXT) genes in response to glucose; binds to promoters and acts both as a transcriptional activator and repressor" |
| 3228 | YKL039W | PTM1 SGDID:S000001522, Chr XI from 362265-363836, Verified ORF, "Protein of unknown function, copurifies with late Golgi vesicles containing the v-SNARE Tlg2p" |
| 3229 | YKL040C | NFU1 SGDID:S000001523, Chr XI from 361471-360701, reverse complement, Verified ORF, "Protein involved in iron metabolism in mitochondria; similar to NifU, which is a protein required for the maturation of the Fe/S clusters of nitrogenase in nitrogen-fixing bacteria" |
| 3230 | YKL041W | VPS24 SGDID:S000001524, Chr XI from 359786-360460, Verified ORF, "One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); forms an ESCRT-III subcomplex with Did4p; involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway" |
| 3231 | YKL042W | SPC42 SGDID:S000001525, Chr XI from 358119-359210, Verified ORF, "Central plaque component of spindle pole body (SPB); involved in SPB duplication, may facilitate attachment of the SPB to the nuclear membrane" |
| 3232 | YKL043W | PHD1 SGDID:S000001526, Chr XI from 356392-357492, Verified ORF, "Transcriptional activator that enhances pseudohyphal growth; regulates expression of FLO11, an adhesin required for pseudohyphal filament formation; similar to StuA, an A. nidulans developmental regulator; potential Cdc28p substrate" |
| 3233 | YKL045W | PRI2 SGDID:S000001528, Chr XI from 353137-354723, Verified ORF, "Subunit of DNA primase, which is required for DNA synthesis and double-strand break repair" |
| 3234 | YKL046C | DCW1 SGDID:S000001529, Chr XI from 352268-350919, reverse complement, Verified ORF, "Putative mannosidase, GPI-anchored membrane protein required for cell wall biosynthesis in bud formation;homologous to Dfg5p" |
| 3235 | YKL047W | YKL047W SGDID:S000001530, Chr XI from 349107-350657, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 3236 | YKL048C | ELM1 SGDID:S000001531, Chr XI from 348780-346858, reverse complement, Verified ORF, "Serine/threonine protein kinase that regulates cellular morphogenesis, septin behavior, and cytokinesis; required for the regulation of other kinases; forms part of the bud neck ring" |
| 3237 | YKL049C | CSE4 SGDID:S000001532, Chr XI from 346408-345719, reverse complement, Verified ORF, "Centromere protein that resembles histones, required for proper kinetochore function; homolog of human CENP-A" |
| 3238 | YKL050C | YKL050C SGDID:S000001533, Chr XI from 345264-342496, reverse complement, Verified ORF, "Protein of unknown function; the YKL050W protein is a target of the SCFCdc4 ubiquitin ligase complex and YKL050W transcription is regulated by Azf1p" |
| 3239 | YKL051W | SFK1 SGDID:S000001534, Chr XI from 340956-342017, Verified ORF, "Plasma membrane protein that may act together with or upstream of Stt4p to generate normal levels of the essential phospholipid PI4P, at least partially mediates proper localization of Stt4p to the plasma membrane" |
| 3240 | YKL052C | ASK1 SGDID:S000001535, Chr XI from 340190-339312, reverse complement, Verified ORF, "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; phosphorylated during the cell cycle by cyclin-dependent kinases" |
| 3241 | YKL053C-A | MDM35 SGDID:S000007243, Chr XI from 339086-338826, reverse complement, Verified ORF, "Mitochondrial intermembrane space cysteine motif protein; mutation affects mitochondrial distribution and morphology" |
| 3242 | YKL054C | DEF1 SGDID:S000001537, Chr XI from 338397-336181, reverse complement, Verified ORF, "RNAPII degradation factor, forms a complex with Rad26p in chromatin, enables ubiquitination and proteolysis of RNAPII present in an elongation complex; mutant is deficient in Zip1p loading onto chromosomes during meiosis" |
| 3243 | YKL055C | OAR1 SGDID:S000001538, Chr XI from 335801-334965, reverse complement, Verified ORF, "Mitochondrial 3-oxoacyl-[acyl-carrier-protein] reductase, may comprise a type II mitochondrial fatty acid synthase along with Mct1p" |
| 3244 | YKL056C | TMA19 SGDID:S000001539, Chr XI from 334559-334056, reverse complement, Verified ORF, "Protein that associates with ribosomes; homolog of translationally controlled tumor protein; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and relocates to the mitochondrial outer surface upon oxidative stress" |
| 3245 | YKL057C | NUP120 SGDID:S000001540, Chr XI from 333613-330500, reverse complement, Verified ORF, "Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), required for even distribution of NPCs around the nuclear envelope, involved in establishment of a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p" |
| 3246 | YKL058W | TOA2 SGDID:S000001541, Chr XI from 329810-330178, Verified ORF, "TFIIA small subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; homologous to smallest subunit of human and Drosophila TFIIA" |
| 3247 | YKL059C | MPE1 SGDID:S000001542, Chr XI from 329087-327762, reverse complement, Verified ORF, "Essential conserved subunit of CPF (cleavage and polyadenylation factor), plays a role in 3' end formation of mRNA via the specific cleavage and polyadenylation of pre-mRNA, contains a putative RNA-binding zinc knuckle motif" |
| 3248 | YKL060C | FBA1 SGDID:S000001543, Chr XI from 327131-326052, reverse complement, Verified ORF, "Fructose 1,6-bisphosphate aldolase, required for glycolysis and gluconeogenesis; catalyzes conversion of fructose 1,6 bisphosphate to glyceraldehyde-3-P and dihydroxyacetone-P; locates to mitochondrial outer surface upon oxidative stress" |
| 3249 | YKL061W | YKL061W SGDID:S000001544, Chr XI from 325415-325756, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endosome" |
| 3250 | YKL062W | MSN4 SGDID:S000001545, Chr XI from 322872-324764, Verified ORF, "Transcriptional activator related to Msn2p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression" |
| 3251 | YKL063C | YKL063C SGDID:S000001546, Chr XI from 321162-320659, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the Golgi" |
| 3252 | YKL064W | MNR2 SGDID:S000001547, Chr XI from 317408-320317, Verified ORF, "Putative magnesium transporter; has similarity to Alr1p and Alr2p, which mediate influx of Mg2+ and other divalent cations" |
| 3253 | YKL065C | YET1 SGDID:S000001548, Chr XI from 316701-316081, reverse complement, Verified ORF, "Endoplasmic reticulum transmembrane protein; may interact with ribosomes, based on co-purification experiments; homolog of human BAP31 protein" |
| 3254 | YKL065W-A | YKL065W-A SGDID:S000113563, Chr XI from 315598-315819, Uncharacterized ORF, "Putative protein of unknown function" |
| 3255 | YKL067W | YNK1 SGDID:S000001550, Chr XI from 314456-314917, Verified ORF, "Nucleoside diphosphate kinase, catalyzes the transfer of gamma phosphates from nucleoside triphosphates, usually ATP, to nucleoside diphosphates by a mechanism that involves formation of an autophosphorylated enzyme intermediate" |
| 3256 | YKL068W | NUP100 SGDID:S000001551, Chr XI from 309843-312722, Verified ORF, "Subunit of the nuclear pore complex (NPC) that is localized to both sides of the pore; contains a repetitive GLFG motif that interacts with mRNA export factor Mex67p and with karyopherin Kap95p; homologous to Nup116p" |
| 3257 | YKL068W-A | YKL068W-A SGDID:S000028524, Chr XI from 308850-309086, Uncharacterized ORF, "Putative protein of unknown function; identified by homology to Ashbya gossypii" |
| 3258 | YKL069W | YKL069W SGDID:S000001552, Chr XI from 306929-307471, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
| 3259 | YKL070W | YKL070W SGDID:S000001553, Chr XI from 305855-306364, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3260 | YKL071W | YKL071W SGDID:S000001554, Chr XI from 304758-305528, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 3261 | YKL072W | STB6 SGDID:S000001555, Chr XI from 299226-301526, Verified ORF, "Protein that binds Sin3p in a two-hybrid assay" |
| 3262 | YKL073W | LHS1 SGDID:S000001556, Chr XI from 296074-298719, Verified ORF, "Molecular chaperone of the endoplasmic reticulum lumen, involved in polypeptide translocation and folding; member of the Hsp70 family; localizes to the lumen of the ER; regulated by the unfolded protein response pathway" |
| 3263 | YKL074C | MUD2 SGDID:S000001557, Chr XI from 295837-294254, reverse complement, Verified ORF, "Protein involved in early pre-mRNA splicing; component of the pre-mRNA-U1 snRNP complex, the commitment complex; interacts with Msl5p/BBP splicing factor and Sub2p; similar to metazoan splicing factor U2AF65" |
| 3264 | YKL075C | YKL075C SGDID:S000001558, Chr XI from 293952-292600, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; proposed to be involved in resistance to streptozotocin and camptothecin" |
| 3265 | YKL077W | YKL077W SGDID:S000001560, Chr XI from 291097-292275, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole" |
| 3266 | YKL078W | DHR2 SGDID:S000001561, Chr XI from 288489-290696, Verified ORF, "Predominantly nucleolar DEAH-box ATP-dependent RNA helicase, required for 18S rRNA synthesis" |
| 3267 | YKL079W | SMY1 SGDID:S000001562, Chr XI from 286247-288217, Verified ORF, "Protein that interacts with Myo2p, proposed to be involved in exocytosis; N-terminal domain is related to the motor domain of kinesins" |
| 3268 | YKL080W | VMA5 SGDID:S000001563, Chr XI from 284674-285852, Verified ORF, "Subunit C of the eight-subunit V1 peripheral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane" |
| 3269 | YKL081W | TEF4 SGDID:S000001564, Chr XI from 282535-282739,283066-284099, Verified ORF, "Translation elongation factor EF-1 gamma" |
| 3270 | YKL082C | RRP14 SGDID:S000001565, Chr XI from 281973-280669, reverse complement, Verified ORF, "Essential protein, constituent of 66S pre-ribosomal particles; interacts with proteins involved in ribosomal biogenesis and cell polarity; member of the SURF-6 family" |
| 3271 | YKL084W | HOT13 SGDID:S000001567, Chr XI from 280153-280503, Verified ORF, "Mitochondrial intermembrane space protein, first component of a pathway mediating assembly of small TIM (Translocase of the Inner Membrane) complexes which escort hydrophobic inner membrane proteins en route to the TIM22 complex" |
| 3272 | YKL085W | MDH1 SGDID:S000001568, Chr XI from 278767-279771, Verified ORF, "Mitochondrial malate dehydrogenase, catalyzes interconversion of malate and oxaloacetate; involved in the tricarboxylic acid (TCA) cycle; phosphorylated" |
| 3273 | YKL086W | SRX1 SGDID:S000001569, Chr XI from 277925-278308, Verified ORF, "Sulfiredoxin, contributes to oxidative stress resistance by reducing cysteine-sulfinic acid groups in the peroxiredoxins Tsa1p and Ahp1p that are formed upon exposure to oxidants; conserved in higher eukaryotes" |
| 3274 | YKL087C | CYT2 SGDID:S000001570, Chr XI from 277507-276833, reverse complement, Verified ORF, "Cytochrome c1 heme lyase, involved in maturation of cytochrome c1, which is a subunit of the mitochondrial ubiquinol-cytochrome-c reductase; links heme covalently to apocytochrome c1" |
| 3275 | YKL088W | YKL088W SGDID:S000001571, Chr XI from 274927-276642, Uncharacterized ORF, "Predicted phosphopantothenoylcysteine decarboxylase, may be involved in coenzyme A biosynthesis; interacts with Sis2p and Vhs3p" |
| 3276 | YKL089W | MIF2 SGDID:S000001572, Chr XI from 273038-274687, Verified ORF, "Kinetochore protein with homology to human CENP-C, required for structural integrity of the spindle during anaphase spindle elongation, interacts with histones H2A, H2B, and H4, phosphorylated by Ipl1p" |
| 3277 | YKL090W | CUE2 SGDID:S000001573, Chr XI from 271522-272853, Verified ORF, "Protein of unknown function; has two CUE domains that bind ubiquitin, which may facilitate intramolecular monoubiquitination" |
| 3278 | YKL091C | YKL091C SGDID:S000001574, Chr XI from 270294-269362, reverse complement, Verified ORF, "Putative homolog of Sec14p, which is a phosphatidylinositol/phosphatidylcholine transfer protein involved in lipid metabolism; localizes to the nucleus" |
| 3279 | YKL092C | BUD2 SGDID:S000001575, Chr XI from 269103-265789, reverse complement, Verified ORF, "GTPase activating factor for Rsr1p/Bud1p required for both axial and bipolar budding patterns; mutants exhibit random budding in all cell types" |
| 3280 | YKL093W | MBR1 SGDID:S000001576, Chr XI from 264433-265452, Verified ORF, "Protein involved in mitochondrial functions and stress response; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants" |
| 3281 | YKL094W | YJU3 SGDID:S000001577, Chr XI from 262993-263934, Verified ORF, "Serine hydrolase with sequence similarity to monoglyceride lipase (MGL), localizes to lipid particles" |
| 3282 | YKL095W | YJU2 SGDID:S000001578, Chr XI from 261921-262757, Verified ORF, "Essential protein required for pre-mRNA splicing; associates transiently with the spliceosomal NTC ("nineteen complex") and acts after Prp2p to promote the first catalytic reaction of splicing" |
| 3283 | YKL096C-B | YKL096C-B SGDID:S000028667, Chr XI from 258866-258717, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 3284 | YKL096W | CWP1 SGDID:S000001579, Chr XI from 260776-261495, Verified ORF, "Cell wall mannoprotein, linked to a beta-1,3- and beta-1,6-glucan heteropolymer through a phosphodiester bond; involved in cell wall organization" |
| 3285 | YKL096W-A | CWP2 SGDID:S000001956, Chr XI from 258897-259175, Verified ORF, "Covalently linked cell wall mannoprotein, major constituent of the cell wall; plays a role in stabilizing the cell wall; involved in low pH resistance; precursor is GPI-anchored" |
| 3286 | YKL098W | YKL098W SGDID:S000001581, Chr XI from 256414-257487, Uncharacterized ORF, "Putative protein of unknown function; YKL098W is synthetically sick with cdc13-1" |
| 3287 | YKL099C | UTP11 SGDID:S000001582, Chr XI from 256116-255364, reverse complement, Verified ORF, "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" |
| 3288 | YKL100C | YKL100C SGDID:S000001583, Chr XI from 255104-253341, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with similarity to a human minor histocompatibility antigen; YKL100C is not an essential gene" |
| 3289 | YKL101W | HSL1 SGDID:S000001584, Chr XI from 248564-253120, Verified ORF, "Nim1p-related protein kinase that regulates the morphogenesis and septin checkpoints; associates with the assembled septin filament; required along with Hsl7p for bud neck recruitment, phosphorylation, and degradation of Swe1p" |
| 3290 | YKL103C | LAP4 SGDID:S000001586, Chr XI from 247326-245782, reverse complement, Verified ORF, "Vacuolar aminopeptidase, often used as a marker protein in studies of autophagy and cytosol to vacuole targeting (CVT) pathway" |
| 3291 | YKL104C | GFA1 SGDID:S000001587, Chr XI from 245017-242864, reverse complement, Verified ORF, "Glutamine-fructose-6-phosphate amidotransferase, catalyzes the formation of glucosamine-6-P and glutamate from fructose-6-P and glutamine in the first step of chitin biosynthesis" |
| 3292 | YKL105C | YKL105C SGDID:S000001588, Chr XI from 242227-238829, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 3293 | YKL106C-A | YKL106C-A SGDID:S000007616, Chr XI from 236910-236791, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by homology to uncharacterized proteins in other fungi" |
| 3294 | YKL106W | AAT1 SGDID:S000001589, Chr XI from 237180-238535, Verified ORF, "Mitochondrial aspartate aminotransferase, catalyzes the conversion of oxaloacetate to aspartate in aspartate and asparagine biosynthesis" |
| 3295 | YKL107W | YKL107W SGDID:S000001590, Chr XI from 235785-236714, Uncharacterized ORF, "Putative protein of unknown function" |
| 3296 | YKL108W | SLD2 SGDID:S000001591, Chr XI from 234070-235431, Verified ORF, "Protein required for DNA replication, phosphorylated in S phase by S-phase cyclin-dependent kinases (Cdks), phosphorylation is essential for DNA replication and for complex formation with Dpb11p; potential Cdc28p substrate" |
| 3297 | YKL109W | HAP4 SGDID:S000001592, Chr XI from 231871-233535, Verified ORF, "Subunit of the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; provides the principal activation function of the complex" |
| 3298 | YKL110C | KTI12 SGDID:S000001593, Chr XI from 229524-228583, reverse complement, Verified ORF, "Protein that plays a role, with Elongator complex, in modification of wobble nucleosides in tRNA; involved in sensitivity to G1 arrest induced by zymocin; interacts with chromatin throughout the genome; also interacts with Cdc19p" |
| 3299 | YKL112W | ABF1 SGDID:S000001595, Chr XI from 226214-228409, Verified ORF, "DNA binding protein with possible chromatin-reorganizing activity involved in transcriptional activation, gene silencing, and DNA replication and repair" |
| 3300 | YKL113C | RAD27 SGDID:S000001596, Chr XI from 225519-224371, reverse complement, Verified ORF, "5' to 3' exonuclease, 5' flap endonuclease, required for Okazaki fragment processing and maturation as well as for long-patch base-excision repair; member of the S. pombe RAD2/FEN1 family" |
| 3301 | YKL114C | APN1 SGDID:S000001597, Chr XI from 224099-222996, reverse complement, Verified ORF, "Major apurinic/apyrimidinic endonuclease, 3'-repair diesterase involved in repair of DNA damage by oxidation and alkylating agents; also functions as a 3'-5' exonuclease to repair 7,8-dihydro-8-oxodeoxyguanosine" |
| 3302 | YKL116C | PRR1 SGDID:S000001599, Chr XI from 222544-220988, reverse complement, Verified ORF, "Serine/threonine protein kinase that inhibits pheromone induced signalling downstream of MAPK, possibly at the level of the Ste12p transcription factor" |
| 3303 | YKL117W | SBA1 SGDID:S000001600, Chr XI from 219968-220618, Verified ORF, "Co-chaperone that binds to and regulates Hsp90 family chaperones; important for pp60v-src activity in yeast; homologous to the mammalian p23 proteins and like p23 can regulate telomerase activity" |
| 3304 | YKL119C | VPH2 SGDID:S000001602, Chr XI from 218861-218214, reverse complement, Verified ORF, "Integral membrane protein required for vacuolar H+-ATPase (V-ATPase) function, although not an actual component of the V-ATPase complex; functions in the assembly of the V-ATPase; localized to the endoplasmic reticulum (ER)" |
| 3305 | YKL120W | OAC1 SGDID:S000001603, Chr XI from 216988-217962, Verified ORF, "Mitochondrial inner membrane transporter, transports oxaloacetate, sulfate, and thiosulfate; member of the mitochondrial carrier family" |
| 3306 | YKL121W | YKL121W SGDID:S000001604, Chr XI from 213786-216344, Uncharacterized ORF, "Putative protein of unknown function" |
| 3307 | YKL122C | SRP21 SGDID:S000001605, Chr XI from 212642-212139, reverse complement, Verified ORF, "Subunit of the signal recognition particle (SRP), which functions in protein targeting to the endoplasmic reticulum membrane; not found in mammalian SRP; forms a pre-SRP structure in the nucleolus that is translocated to the cytoplasm" |
| 3308 | YKL124W | SSH4 SGDID:S000001607, Chr XI from 210237-211976, Verified ORF, "Specificity factor required for Rsp5p-dependent ubiquitination and sorting of cargo proteins at the multivesicular body; identified as a high-copy suppressor of a SHR3 deletion, increasing steady-state levels of amino acid permeases" |
| 3309 | YKL125W | RRN3 SGDID:S000001608, Chr XI from 207891-209774, Verified ORF, "Protein required for transcription of rDNA by RNA polymerase I; transcription factor independent of DNA template; involved in recruitment of RNA polymerase I to rDNA" |
| 3310 | YKL126W | YPK1 SGDID:S000001609, Chr XI from 205351-207393, Verified ORF, "Serine/threonine protein kinase required for receptor-mediated endocytosis; involved in sphingolipid-mediated and cell integrity signaling pathways; localized to the bud neck, cytosol and plasma membrane; homolog of mammalian kinase SGK" |
| 3311 | YKL127W | PGM1 SGDID:S000001610, Chr XI from 203185-204897, Verified ORF, "Phosphoglucomutase, minor isoform; catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism" |
| 3312 | YKL128C | PMU1 SGDID:S000001611, Chr XI from 201415-200528, reverse complement, Verified ORF, "Putative phosphomutase, contains a region homologous to the active site of phosphomutases; overexpression suppresses the histidine auxotrophy of an ade3 ade16 ade17 triple mutant and the temperature sensitivity of a tps2 mutant" |
| 3313 | YKL129C | MYO3 SGDID:S000001612, Chr XI from 200163-196348, reverse complement, Verified ORF, "One of two type I myosins; localizes to actin cortical patches; deletion of MYO3 has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization" |
| 3314 | YKL130C | SHE2 SGDID:S000001613, Chr XI from 196027-195287, reverse complement, Verified ORF, "RNA-binding protein that binds specific mRNAs and interacts with She3p; part of the mRNA localization machinery that restricts accumulation of certain proteins to the bud" |
| 3315 | YKL132C | RMA1 SGDID:S000001615, Chr XI from 194865-193573, reverse complement, Verified ORF, "Putative dihydrofolate synthetase; has similarity to Fol3p and to E. coli folylpolyglutamate synthetase/dihydrofolate synthetase; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3316 | YKL133C | YKL133C SGDID:S000001616, Chr XI from 193069-191678, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 3317 | YKL134C | OCT1 SGDID:S000001617, Chr XI from 191441-189129, reverse complement, Verified ORF, "Mitochondrial intermediate peptidase, cleaves N-terminal residues of a subset of proteins upon import, after their cleavage by mitochondrial processing peptidase (Mas1p-Mas2p); may contribute to mitochondrial iron homeostasis" |
| 3318 | YKL135C | APL2 SGDID:S000001618, Chr XI from 188645-186465, reverse complement, Verified ORF, "Beta-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in clathrin-dependent Golgi protein sorting" |
| 3319 | YKL137W | CMC1 SGDID:S000001620, Chr XI from 185962-186297, Verified ORF, "Evolutionarily conserved copper-binding protein of the mitochondrial inner membrane, may be involved in delivering copper from the matrix to the cytochrome c oxidase complex; contains a twin CX9C motif" |
| 3320 | YKL138C | MRPL31 SGDID:S000001621, Chr XI from 185686-185291, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 3321 | YKL138C-A | HSK3 SGDID:S000028421, Chr XI from 185017-184808, reverse complement, Verified ORF, "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" |
| 3322 | YKL139W | CTK1 SGDID:S000001622, Chr XI from 182963-184549, Verified ORF, "Catalytic (alpha) subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing" |
| 3323 | YKL140W | TGL1 SGDID:S000001623, Chr XI from 180784-182430, Verified ORF, "Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes" |
| 3324 | YKL141W | SDH3 SGDID:S000001624, Chr XI from 179672-180268, Verified ORF, "Cytochrome b subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone" |
| 3325 | YKL142W | MRP8 SGDID:S000001625, Chr XI from 178520-179179, Verified ORF, "Putative mitochondrial ribosomal protein, has similarity to E. coli ribosomal protein S2" |
| 3326 | YKL143W | LTV1 SGDID:S000001626, Chr XI from 176786-178177, Verified ORF, "Component of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; required for ribosomal small subunit export from nucleus; required for growth at low temperature" |
| 3327 | YKL144C | RPC25 SGDID:S000001627, Chr XI from 176486-175848, reverse complement, Verified ORF, "RNA polymerase III subunit C25, required for transcription initiation; forms a heterodimer with Rpc17p; paralog of Rpb7p" |
| 3328 | YKL145W | RPT1 SGDID:S000001628, Chr XI from 174218-175621, Verified ORF, "One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for optimal CDC20 transcription; interacts with Rpn12p and the E3 ubiquitin-protein ligase Ubr1p" |
| 3329 | YKL146W | AVT3 SGDID:S000001629, Chr XI from 171788-173866, Verified ORF, "Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" |
| 3330 | YKL148C | SDH1 SGDID:S000001631, Chr XI from 171134-169212, reverse complement, Verified ORF, "Flavoprotein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone" |
| 3331 | YKL149C | DBR1 SGDID:S000001632, Chr XI from 168834-167617, reverse complement, Verified ORF, "RNA lariat debranching enzyme, involved in intron turnover; required for efficient Ty1 transposition" |
| 3332 | YKL150W | MCR1 SGDID:S000001633, Chr XI from 166549-167457, Verified ORF, "Mitochondrial NADH-cytochrome b5 reductase, involved in ergosterol biosynthesis" |
| 3333 | YKL151C | YKL151C SGDID:S000001634, Chr XI from 165935-164922, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 3334 | YKL152C | GPM1 SGDID:S000001635, Chr XI from 164390-163647, reverse complement, Verified ORF, "Tetrameric phosphoglycerate mutase, mediates the conversion of 3-phosphoglycerate to 2-phosphoglycerate during glycolysis and the reverse reaction during gluconeogenesis" |
| 3335 | YKL154W | SRP102 SGDID:S000001637, Chr XI from 161606-162340, Verified ORF, "Signal recognition particle (SRP) receptor beta subunit; involved in SRP-dependent protein targeting; anchors Srp101p to the ER membrane" |
| 3336 | YKL155C | RSM22 SGDID:S000001638, Chr XI from 161347-159461, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 3337 | YKL156W | RPS27A SGDID:S000001639, Chr XI from 158619-158621,158972-159217, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps27Bp and has similarity to rat S27 ribosomal protein" |
| 3338 | YKL157W | APE2 SGDID:S000001640, Chr XI from 154996-155276,155660-158186, Verified ORF, "Zinc-dependent metallopeptidase yscII, may have a role in obtaining leucine from dipeptide substrates; sequence coordinates have changed since RT-PCR analysis showed that the adjacent ORF YKL158W comprises the 5' exon of APE2/YKL157W" |
| 3339 | YKL159C | RCN1 SGDID:S000001642, Chr XI from 154456-153821, reverse complement, Verified ORF, "Protein involved in calcineurin regulation during calcium signaling; has similarity to H. sapiens DSCR1 which is found in the Down Syndrome candidate region" |
| 3340 | YKL160W | ELF1 SGDID:S000001643, Chr XI from 153274-153711, Verified ORF, "Transcription elongation factor that contains a conserved zinc finger domain; implicated in the maintenance of proper chromatin structure in actively transcribed regions; deletion inhibits Brome mosaic virus (BMV) gene expression" |
| 3341 | YKL161C | YKL161C SGDID:S000001644, Chr XI from 150692-149391, reverse complement, Verified ORF, "Protein kinase implicated in the Slt2p mitogen-activated (MAP) kinase signaling pathway; associates with Rlm1p" |
| 3342 | YKL162C | YKL162C SGDID:S000001645, Chr XI from 148843-147635, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion" |
| 3343 | YKL163W | PIR3 SGDID:S000001646, Chr XI from 144406-145383, Verified ORF, "O-glycosylated covalently-bound cell wall protein required for cell wall stability; expression is cell cycle regulated, peaking in M/G1 and also subject to regulation by the cell integrity pathway" |
| 3344 | YKL164C | PIR1 SGDID:S000001647, Chr XI from 142824-141799, reverse complement, Verified ORF, "O-glycosylated protein required for cell wall stability; attached to the cell wall via beta-1,3-glucan; mediates mitochondrial translocation of Apn1p; expression regulated by the cell integrity pathway and by Swi5p during the cell cycle" |
| 3345 | YKL165C | MCD4 SGDID:S000001648, Chr XI from 140696-137937, reverse complement, Verified ORF, "Protein involved in glycosylphosphatidylinositol (GPI) anchor synthesis; multimembrane-spanning protein that localizes to the endoplasmic reticulum; highly conserved among eukaryotes" |
| 3346 | YKL166C | TPK3 SGDID:S000001649, Chr XI from 135710-134514, reverse complement, Verified ORF, "cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk1p and Tpk2p" |
| 3347 | YKL167C | MRP49 SGDID:S000001650, Chr XI from 134139-133726, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation" |
| 3348 | YKL168C | KKQ8 SGDID:S000001651, Chr XI from 133467-131293, reverse complement, Verified ORF, "Putative serine/threonine protein kinase with unknown cellular role" |
| 3349 | YKL170W | MRPL38 SGDID:S000001653, Chr XI from 130639-131055, Verified ORF, "Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL34 and YmL38) on two-dimensional SDS gels" |
| 3350 | YKL171W | YKL171W SGDID:S000001654, Chr XI from 127480-130266, Uncharacterized ORF, "Putative protein of unknown function; predicted protein kinase; implicated in proteasome function; epitope-tagged protein localizes to the cytoplasm" |
| 3351 | YKL172W | EBP2 SGDID:S000001655, Chr XI from 125764-127047, Verified ORF, "Essential protein required for the maturation of 25S rRNA and 60S ribosomal subunit assembly, localizes to the nucleolus; constituent of 66S pre-ribosomal particles" |
| 3352 | YKL173W | SNU114 SGDID:S000001656, Chr XI from 122522-125548, Verified ORF, "GTPase component of U5 snRNP involved in mRNA splicing via spliceosome; binds directly to U5 snRNA; proposed to be involved in conformational changes of the spliceosome; similarity to ribosomal translocation factor EF-2" |
| 3353 | YKL174C | TPO5 SGDID:S000001657, Chr XI from 122241-120385, reverse complement, Verified ORF, "Protein involved in excretion of putrescine and spermidine; putative polyamine transporter in the Golgi or post-Golgi vesicles" |
| 3354 | YKL175W | ZRT3 SGDID:S000001658, Chr XI from 118798-120309, Verified ORF, "Vacuolar membrane zinc transporter, transports zinc from storage in the vacuole to the cytoplasm when needed; transcription is induced under conditions of zinc deficiency" |
| 3355 | YKL176C | LST4 SGDID:S000001659, Chr XI from 117991-115505, reverse complement, Verified ORF, "Protein possibly involved in a post-Golgi secretory pathway; required for the transport of nitrogen-regulated amino acid permease Gap1p from the Golgi to the cell surface" |
| 3356 | YKL178C | STE3 SGDID:S000001661, Chr XI from 114632-113220, reverse complement, Verified ORF, "Receptor for a factor receptor, transcribed in alpha cells and required for mating by alpha cells, couples to MAP kinase cascade to mediate pheromone response; ligand bound receptors are endocytosed and recycled to the plasma membrane; GPCR" |
| 3357 | YKL179C | COY1 SGDID:S000001662, Chr XI from 112508-110469, reverse complement, Verified ORF, "Golgi membrane protein with similarity to mammalian CASP; genetic interactions with GOS1 (encoding a Golgi snare protein) suggest a role in Golgi function" |
| 3358 | YKL180W | RPL17A SGDID:S000001663, Chr XI from 109274-109582,109889-110134, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl17Bp and has similarity to E. coli L22 and rat L17 ribosomal proteins; copurifies with the Dam1 complex (aka DASH complex)" |
| 3359 | YKL181W | PRS1 SGDID:S000001664, Chr XI from 107321-108604, Verified ORF, "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes" |
| 3360 | YKL182W | FAS1 SGDID:S000001665, Chr XI from 100676-106831, Verified ORF, "Beta subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains acetyltransacylase, dehydratase, enoyl reductase, malonyl transacylase, and palmitoyl transacylase activities" |
| 3361 | YKL183C-A | YKL183C-A SGDID:S000028558, Chr XI from 98612-98400, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 3362 | YKL183W | LOT5 SGDID:S000001666, Chr XI from 98726-99646, Verified ORF, "Protein of unknown function; gene expression increases in cultures shifted to a lower temperature" |
| 3363 | YKL184W | SPE1 SGDID:S000001667, Chr XI from 96762-98162, Verified ORF, "Ornithine decarboxylase, catalyzes the first step in polyamine biosynthesis; degraded in a proteasome-dependent manner in the presence of excess polyamines" |
| 3364 | YKL185W | ASH1 SGDID:S000001668, Chr XI from 94504-96270, Verified ORF, "Zinc-finger inhibitor of HO transcription; mRNA is localized and translated in the distal tip of anaphase cells, resulting in accumulation of Ash1p in daughter cell nuclei and inhibition of HO expression; potential Cdc28p substrate" |
| 3365 | YKL186C | MTR2 SGDID:S000001669, Chr XI from 93303-92749, reverse complement, Verified ORF, "mRNA transport regulator, essential nuclear protein; Mex67p and Mtr2p form a mRNA export complex which binds to RNA" |
| 3366 | YKL187C | YKL187C SGDID:S000001670, Chr XI from 91541-89289, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies" |
| 3367 | YKL188C | PXA2 SGDID:S000001671, Chr XI from 88791-86230, reverse complement, Verified ORF, "Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter and ALD-related proteins" |
| 3368 | YKL189W | HYM1 SGDID:S000001672, Chr XI from 84709-85908, Verified ORF, "Component of the RAM signaling network that is involved in regulation of Ace2p activity and cellular morphogenesis, interacts with Kic1p and Sog2p, localizes to sites of polarized growth during budding and during the mating response" |
| 3369 | YKL190W | CNB1 SGDID:S000001673, Chr XI from 82952-83003,83080-83555, Verified ORF, "Calcineurin B; the regulatory subunit of calcineurin, a Ca++/calmodulin-regulated type 2B protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is encoded by CNA1 and/or CMP1" |
| 3370 | YKL191W | DPH2 SGDID:S000001674, Chr XI from 81040-82644, Verified ORF, "Protein required, along with Dph1p, Kti11p, Jjj3p, and Dph5p, for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); may act in a complex with Dph1p and Kti11p" |
| 3371 | YKL192C | ACP1 SGDID:S000001675, Chr XI from 80542-80165, reverse complement, Verified ORF, "Mitochondrial matrix acyl carrier protein, involved in biosynthesis of octanoate, which is a precursor to lipoic acid; activated by phosphopantetheinylation catalyzed by Ppt2p" |
| 3372 | YKL193C | SDS22 SGDID:S000001676, Chr XI from 79887-78871, reverse complement, Verified ORF, "Conserved nuclear regulatory subunit of Glc7p type 1 protein serine-threonine phosphatase (PP1), functions positively with Glc7p to promote dephosphorylation of nuclear substrates required for chromosome transmission during mitosis" |
| 3373 | YKL194C | MST1 SGDID:S000001677, Chr XI from 78651-77263, reverse complement, Verified ORF, "Mitochondrial threonyl-tRNA synthetase" |
| 3374 | YKL195W | MIA40 SGDID:S000001678, Chr XI from 75826-77037, Verified ORF, "Essential protein of the mitochondrial intermembrane space (IMS); promotes retention of newly imported proteins; may do so by stabilizing client protein folding as part of a disulfide relay system or transferring metal to client proteins" |
| 3375 | YKL196C | YKT6 SGDID:S000001679, Chr XI from 75539-74937, reverse complement, Verified ORF, "Vesicle membrane protein (v-SNARE) with acyltransferase activity; involved in trafficking to and within the Golgi, endocytic trafficking to the vacuole, and vacuolar fusion; membrane localization due to prenylation at the carboxy-terminus" |
| 3376 | YKL197C | PEX1 SGDID:S000001680, Chr XI from 73870-70739, reverse complement, Verified ORF, "AAA-peroxin that heterodimerizes with AAA-peroxin Pex6p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol; induced by oleic acid and upregulated during anaerobiosis" |
| 3377 | YKL198C | PTK1 SGDID:S000001681, Chr XI from 70223-68274, reverse complement, Verified ORF, "Putative serine/threonine protein kinase that regulates spermine uptake; involved in polyamine transport; possible mitochondrial protein" |
| 3378 | YKL201C | MNN4 SGDID:S000001684, Chr XI from 67467-63931, reverse complement, Verified ORF, "Putative positive regulator of mannosylphosphate transferase (Mnn6p), involved in mannosylphosphorylation of N-linked oligosaccharides; expression increases in late-logarithmic and stationary growth phases" |
| 3379 | YKL203C | TOR2 SGDID:S000001686, Chr XI from 63360-55936, reverse complement, Verified ORF, "PIK-related protein kinase and rapamycin target; subunit of TORC1, a complex that regulates growth in response to nutrients and TORC2, a complex that regulates cell-cycle dependent polarization of the actin cytoskeleton; involved in meiosis" |
| 3380 | YKL204W | EAP1 SGDID:S000001687, Chr XI from 53705-55603, Verified ORF, "eIF4E-associated protein, binds eIF4E and inhibits cap-dependent translation, also functions independently of eIF4E to maintain genetic stability; plays a role in cell growth, implicated in the TOR signaling cascade" |
| 3381 | YKL205W | LOS1 SGDID:S000001688, Chr XI from 50052-53354, Verified ORF, "Nuclear pore protein involved in nuclear export of pre-tRNA" |
| 3382 | YKL206C | ADD66 SGDID:S000001689, Chr XI from 49810-49007, reverse complement, Verified ORF, "Protein involved in 20S proteasome assembly; forms a heterodimer with Pba1p that binds to proteasome precursors; similar to human PAC2 constituent of the PAC1-PAC2 complex involved in proteasome assembly" |
| 3383 | YKL207W | YKL207W SGDID:S000001690, Chr XI from 48195-48956, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media" |
| 3384 | YKL208W | CBT1 SGDID:S000001691, Chr XI from 47158-47973, Verified ORF, "Protein involved in 5' end processing of mitochondrial COB, 15S_rRNA, and RPM1 transcripts; may also have a role in 3' end processing of the COB pre-mRNA; displays genetic interaction with cell cycle-regulated kinase Dbf2p" |
| 3385 | YKL209C | STE6 SGDID:S000001692, Chr XI from 46296-42424, reverse complement, Verified ORF, "Plasma membrane ATP-binding cassette (ABC) transporter required for the export of a-factor, catalyzes ATP hydrolysis coupled to a-factor transport; contains 12 transmembrane domains and two ATP binding domains; expressed only in MATa cells" |
| 3386 | YKL210W | UBA1 SGDID:S000001693, Chr XI from 39164-42238, Verified ORF, "Ubiquitin activating enzyme (E1), involved in ubiquitin-mediated protein degradation and essential for viability" |
| 3387 | YKL211C | TRP3 SGDID:S000001694, Chr XI from 38154-36700, reverse complement, Verified ORF, "Bifunctional enzyme exhibiting both indole-3-glycerol-phosphate synthase and anthranilate synthase activities, forms multifunctional hetero-oligomeric anthranilate synthase:indole-3-glycerol phosphate synthase enzyme complex with Trp2p" |
| 3388 | YKL212W | SAC1 SGDID:S000001695, Chr XI from 34544-36415, Verified ORF, "Phosphatidylinositol (PI) phosphatase, involved in hydrolysis of PI 3-phosphate, PI 4-phosphate and PI 3,5-bisphosphate to PI; membrane protein localizes to ER and Golgi; involved in protein trafficking, secretion and inositol metabolism" |
| 3389 | YKL213C | DOA1 SGDID:S000001696, Chr XI from 34108-31961, reverse complement, Verified ORF, "WD repeat protein required for ubiquitin-mediated protein degradation, forms complex with Cdc48p, plays a role in controlling cellular ubiquitin concentration; also promotes efficient NHEJ in postdiauxic/stationary phase" |
| 3390 | YKL214C | YRA2 SGDID:S000001697, Chr XI from 31694-31083, reverse complement, Verified ORF, "Member of the REF (RNA and export factor binding proteins) family; when overexpressed, can substitute for the function of Yra1p in export of poly(A)+ mRNA from the nucleus" |
| 3391 | YKL215C | YKL215C SGDID:S000001698, Chr XI from 30688-26828, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 3392 | YKL216W | URA1 SGDID:S000001699, Chr XI from 25216-26160, Verified ORF, "Dihydroorotate dehydrogenase, catalyzes the fourth enzymatic step in the de novo biosynthesis of pyrimidines, converting dihydroorotic acid into orotic acid" |
| 3393 | YKL217W | JEN1 SGDID:S000001700, Chr XI from 22234-24084, Verified ORF, "Lactate transporter, required for uptake of lactate and pyruvate; phosphorylated; expression is derepressed by transcriptional activator Cat8p during respiratory growth, and repressed in the presence of glucose, fructose, and mannose" |
| 3394 | YKL218C | SRY1 SGDID:S000001701, Chr XI from 18339-17359, reverse complement, Verified ORF, "3-hydroxyaspartate dehydratase, deaminates L-threo-3-hydroxyaspartate to form oxaloacetate and ammonia; required for survival in the presence of hydroxyaspartate" |
| 3395 | YKL219W | COS9 SGDID:S000001702, Chr XI from 14485-15708, Verified ORF, "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" |
| 3396 | YKL220C | FRE2 SGDID:S000001703, Chr XI from 11227-9092, reverse complement, Verified ORF, "Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low iron levels but not by low copper levels" |
| 3397 | YKL221W | MCH2 SGDID:S000001704, Chr XI from 6108-7529, Verified ORF, "Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport" |
| 3398 | YKL222C | YKL222C SGDID:S000001705, Chr XI from 5621-3504, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; similar to transcriptional regulators from the zinc cluster (binuclear cluster) family; null mutant is sensitive to caffeine" |
| 3399 | YKL224C | YKL224C SGDID:S000001707, Chr XI from 2182-1811, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 3400 | YKR001C | VPS1 SGDID:S000001709, Chr XI from 442365-440251, reverse complement, Verified ORF, "Dynamin-like GTPase required for vacuolar sorting; also involved in actin cytoskeleton organization, late Golgi-retention of some proteins, regulating peroxisome biogenesis" |
| 3401 | YKR002W | PAP1 SGDID:S000001710, Chr XI from 442875-444581, Verified ORF, "Poly(A) polymerase, one of three factors required for mRNA 3'-end polyadenylation, forms multiprotein complex with polyadenylation factor I (PF I), also required for mRNA nuclear export; may also polyadenylate rRNAs" |
| 3402 | YKR003W | OSH6 SGDID:S000001711, Chr XI from 445024-446370, Verified ORF, "Member of an oxysterol-binding protein family with overlapping, redundant functions in sterol metabolism and which collectively perform a function essential for viability; GFP-fusion protein localizes to the cell periphery" |
| 3403 | YKR004C | ECM9 SGDID:S000001712, Chr XI from 447679-447454,447349-446442, reverse complement, Verified ORF, "Non-essential protein of unknown function" |
| 3404 | YKR005C | YKR005C SGDID:S000001713, Chr XI from 449810-449664,449594-448164, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 3405 | YKR006C | MRPL13 SGDID:S000001714, Chr XI from 450860-450066, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation" |
| 3406 | YKR007W | MEH1 SGDID:S000001715, Chr XI from 451077-451631, Verified ORF, "Component of the EGO complex, which is involved in the regulation of microautophagy, and of the GSE complex, which is required for proper sorting of amino acid permease Gap1p; loss results in a defect in vacuolar acidification" |
| 3407 | YKR008W | RSC4 SGDID:S000001716, Chr XI from 451844-453721, Verified ORF, "Component of the RSC chromatin remodeling complex; found in close proximity to nucleosomal DNA; displaced from the surface of nucleosomal DNA after chromatin remodeling" |
| 3408 | YKR009C | FOX2 SGDID:S000001717, Chr XI from 456697-453995, reverse complement, Verified ORF, "Multifunctional enzyme of the peroxisomal fatty acid beta-oxidation pathway; has 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA hydratase activities" |
| 3409 | YKR010C | TOF2 SGDID:S000001718, Chr XI from 460882-458567, reverse complement, Verified ORF, "Nonessential mitochondrial protein of unknown function with sequence similarity to Net1p; identified as a topoisomerase I (Top1p) binding protein; displays synthetic genetic interactions with TOP1 and HPR1" |
| 3410 | YKR011C | YKR011C SGDID:S000001719, Chr XI from 462339-461278, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus" |
| 3411 | YKR013W | PRY2 SGDID:S000001721, Chr XI from 463602-464591, Verified ORF, "Protein of unknown function, has similarity to Pry1p and Pry3p and to the plant PR-1 class of pathogen related proteins" |
| 3412 | YKR014C | YPT52 SGDID:S000001722, Chr XI from 465714-465010, reverse complement, Verified ORF, "GTPase, similar to Ypt51p and Ypt53p and to mammalian rab5; required for vacuolar protein sorting and endocytosis" |
| 3413 | YKR015C | YKR015C SGDID:S000001723, Chr XI from 468310-466604, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 3414 | YKR016W | YKR016W SGDID:S000001724, Chr XI from 469360-470982, Uncharacterized ORF, "Protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays decreased frequency of mitochondrial genome loss and severe growth defect in minimal glycerol media" |
| 3415 | YKR017C | YKR017C SGDID:S000001725, Chr XI from 472992-471337, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; contains a RING finger motif" |
| 3416 | YKR018C | YKR018C SGDID:S000001726, Chr XI from 475543-473366, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
| 3417 | YKR019C | IRS4 SGDID:S000001727, Chr XI from 477706-475859, reverse complement, Verified ORF, "EH domain-containing protein involved in regulating phosphatidylinositol 4,5-bisphosphate levels and autophagy; Irs4p and Tax4p bind and activate the PtdIns phosphatase Inp51p; Irs4p and Tax4p are involved in localizing Atg17p to the PAS" |
| 3418 | YKR020W | VPS51 SGDID:S000001728, Chr XI from 477981-478475, Verified ORF, "Component of the GARP (Golgi-associated retrograde protein) complex, Vps51p-Vps52p-Vps53p-Vps54p, which is required for the recycling of proteins from endosomes to the late Golgi; links the (VFT/GARP) complex to the SNARE Tlg1p" |
| 3419 | YKR021W | ALY1 SGDID:S000001729, Chr XI from 478877-481624, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 3420 | YKR022C | NTR2 SGDID:S000001730, Chr XI from 482782-481814, reverse complement, Verified ORF, "Essential protein that forms a dimer with Ntr1p; also forms a trimer, with Ntr2p and the DExD/H-box RNA helicase Prp43p, that is involved in spliceosome disassembly" |
| 3421 | YKR023W | YKR023W SGDID:S000001731, Chr XI from 483062-484654, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3422 | YKR024C | DBP7 SGDID:S000001732, Chr XI from 487015-484787, reverse complement, Verified ORF, "Putative ATP-dependent RNA helicase of the DEAD-box family involved in ribosomal biogenesis" |
| 3423 | YKR025W | RPC37 SGDID:S000001733, Chr XI from 487413-488261, Verified ORF, "RNA polymerase III subunit C37" |
| 3424 | YKR026C | GCN3 SGDID:S000001734, Chr XI from 489298-488381, reverse complement, Verified ORF, "Alpha subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a positive regulator of GCN4 expression" |
| 3425 | YKR027W | BCH2 SGDID:S000001735, Chr XI from 491007-493304, Verified ORF, "Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane" |
| 3426 | YKR028W | SAP190 SGDID:S000001736, Chr XI from 493900-497196, Verified ORF, "Protein that forms a complex with the Sit4p protein phosphatase and is required for its function; member of a family of similar proteins including Sap4p, Sap155p, and Sap185p" |
| 3427 | YKR029C | SET3 SGDID:S000001737, Chr XI from 499475-497220, reverse complement, Verified ORF, "Defining member of the SET3 histone deacetylase complex which is a meiosis-specific repressor of sporulation genes; necessary for efficient transcription by RNAPII; one of two yeast proteins that contains both SET and PHD domains" |
| 3428 | YKR030W | GMH1 SGDID:S000001738, Chr XI from 499924-500745, Verified ORF, "Golgi membrane protein of unknown function, interacts with Gea1p and Gea2p; required for localization of Gea2p; computational analysis suggests a possible role in either cell wall synthesis or protein-vacuolar targeting" |
| 3429 | YKR031C | SPO14 SGDID:S000001739, Chr XI from 506037-500986, reverse complement, Verified ORF, "Phospholipase D, catalyzes the hydrolysis of phosphatidylcholine, producing choline and phosphatidic acid; involved in Sec14p-independent secretion; required for meiosis and spore formation; differently regulated in secretion and meiosis" |
| 3430 | YKR034W | DAL80 SGDID:S000001742, Chr XI from 506540-507349, Verified ORF, "Negative regulator of genes in multiple nitrogen degradation pathways; expression is regulated by nitrogen levels and by Gln3p; member of the GATA-binding family, forms homodimers and heterodimers with Deh1p" |
| 3431 | YKR035W-A | DID2 SGDID:S000006435, Chr XI from 507581-508195, Verified ORF, "Class E protein of the vacuolar protein-sorting (Vps) pathway; binds Vps4p and directs it to dissociate ESCRT-III complexes; forms a functional and physical complex with Ist1p; human ortholog may be altered in breast tumors" |
| 3432 | YKR036C | CAF4 SGDID:S000001744, Chr XI from 510275-508344, reverse complement, Verified ORF, "WD40 repeat-containing protein associated with the CCR4-NOT complex, interacts in a Ccr4p-dependent manner with Ssn2p; also interacts with Fis1p, Mdv1p and Dnm1p and plays a role in mitochondrial fission" |
| 3433 | YKR037C | SPC34 SGDID:S000001745, Chr XI from 511439-510552, reverse complement, Verified ORF, "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; also localized to nuclear side of spindle pole body" |
| 3434 | YKR038C | KAE1 SGDID:S000001746, Chr XI from 512801-511641, reverse complement, Verified ORF, "Putative glycoprotease proposed to be in transcription as a component of the EKC protein complex with Bud32p, Cgi121p, Pcc1p, and Gon7p; also identified as a component of the KEOPS protein complex" |
| 3435 | YKR039W | GAP1 SGDID:S000001747, Chr XI from 514705-516513, Verified ORF, "General amino acid permease; localization to the plasma membrane is regulated by nitrogen source" |
| 3436 | YKR041W | YKR041W SGDID:S000001749, Chr XI from 517840-518592, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
| 3437 | YKR042W | UTH1 SGDID:S000001750, Chr XI from 519169-520266, Verified ORF, "Mitochondrial outer membrane and cell wall localized SUN family member required for mitochondrial autophagy; involved in the oxidative stress response, life span during starvation, mitochondrial biogenesis, and cell death" |
| 3438 | YKR043C | YKR043C SGDID:S000001751, Chr XI from 521354-520539, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
| 3439 | YKR044W | UIP5 SGDID:S000001752, Chr XI from 521657-522988, Verified ORF, "Protein of unknown function that interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates" |
| 3440 | YKR045C | YKR045C SGDID:S000001753, Chr XI from 523611-523060, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm" |
| 3441 | YKR046C | PET10 SGDID:S000001754, Chr XI from 524716-523865, reverse complement, Verified ORF, "Protein of unknown function that co-purifies with lipid particles; expression pattern suggests a role in respiratory growth; computational analysis of large-scale protein-protein interaction data suggests a role in ATP/ADP exchange" |
| 3442 | YKR048C | NAP1 SGDID:S000001756, Chr XI from 526282-525029, reverse complement, Verified ORF, "Protein that interacts with mitotic cyclin Clb2p; required for the regulation of microtubule dynamics during mitosis; controls bud morphogenesis; involved in the transport of H2A and H2B histones to the nucleus; phosphorylated by CK2" |
| 3443 | YKR049C | FMP46 SGDID:S000001757, Chr XI from 526873-526472, reverse complement, Verified ORF, "Putative redox protein containing a thioredoxin fold; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3444 | YKR050W | TRK2 SGDID:S000001758, Chr XI from 527457-530126, Verified ORF, "Component of the Trk1p-Trk2p potassium transport system" |
| 3445 | YKR051W | YKR051W SGDID:S000001759, Chr XI from 530588-531844, Uncharacterized ORF, "Putative protein of unknown function" |
| 3446 | YKR052C | MRS4 SGDID:S000001760, Chr XI from 533106-532192, reverse complement, Verified ORF, "Mitochondrial iron transporter of the mitochondrial carrier family (MCF), very similar to and functionally redundant with Mrs3p; functions under low-iron conditions; may transport other cations in addition to iron" |
| 3447 | YKR053C | YSR3 SGDID:S000001761, Chr XI from 534923-533709, reverse complement, Verified ORF, "Dihydrosphingosine 1-phosphate phosphatase, membrane protein involved in sphingolipid metabolism; has similarity to Lcb3p" |
| 3448 | YKR054C | DYN1 SGDID:S000001762, Chr XI from 547567-535289, reverse complement, Verified ORF, "Cytoplasmic heavy chain dynein, microtubule motor protein, required for anaphase spindle elongation; involved in spindle assembly, chromosome movement, and spindle orientation during cell division, targeted to microtubule tips by Pac1p" |
| 3449 | YKR055W | RHO4 SGDID:S000001763, Chr XI from 547858-548733, Verified ORF, "Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely to be involved in the establishment of cell polarity" |
| 3450 | YKR056W | TRM2 SGDID:S000001764, Chr XI from 549090-551009, Verified ORF, "tRNA methyltransferase, 5-methylates the uridine residue at position 54 of tRNAs and may also have a role in tRNA stabilization or maturation; endo-exonuclease with a role in DNA repair" |
| 3451 | YKR057W | RPS21A SGDID:S000001765, Chr XI from 551299-551322,551645-551884, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps21Bp and has similarity to rat S21 ribosomal protein" |
| 3452 | YKR058W | GLG1 SGDID:S000001766, Chr XI from 552412-554262, Verified ORF, "Self-glucosylating initiator of glycogen synthesis, also glucosylates n-dodecyl-beta-D-maltoside; similar to mammalian glycogenin" |
| 3453 | YKR059W | TIF1 SGDID:S000001767, Chr XI from 554629-555816, Verified ORF, "Translation initiation factor eIF4A, identical to Tif2p; DEA(D/H)-box RNA helicase that couples ATPase activity to RNA binding and unwinding; forms a dumbbell structure of two compact domains connected by a linker; interacts with eIF4G" |
| 3454 | YKR060W | UTP30 SGDID:S000001768, Chr XI from 556160-556984, Verified ORF, "Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data" |
| 3455 | YKR061W | KTR2 SGDID:S000001769, Chr XI from 557319-558596, Verified ORF, "Mannosyltransferase involved in N-linked protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family" |
| 3456 | YKR062W | TFA2 SGDID:S000001770, Chr XI from 559308-560294, Verified ORF, "TFIIE small subunit, involved in RNA polymerase II transcription initiation" |
| 3457 | YKR063C | LAS1 SGDID:S000001771, Chr XI from 561939-560431, reverse complement, Verified ORF, "Essential nuclear protein possibly involved in bud formation and morphogenesis; mutants require the SSD1-v allele for viability" |
| 3458 | YKR064W | OAF3 SGDID:S000001772, Chr XI from 562189-564780, Verified ORF, "Zinc cluster protein; regulates transcription in response to oleate levels; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3459 | YKR065C | PAM17 SGDID:S000001773, Chr XI from 565534-564941, reverse complement, Verified ORF, "Presequence translocase-associated motor subunit, required for stable complex formation between cochaperones Pam16p and Pam18p, promotes association of Pam16p-Pam18p with the presequence translocase" |
| 3460 | YKR066C | CCP1 SGDID:S000001774, Chr XI from 566840-565755, reverse complement, Verified ORF, "Mitochondrial cytochrome-c peroxidase; degrades reactive oxygen species in mitochondria, involved in the response to oxidative stress" |
| 3461 | YKR067W | GPT2 SGDID:S000001775, Chr XI from 567560-569791, Verified ORF, "Glycerol-3-phosphate/dihydroxyacetone phosphate dual substrate-specific sn-1 acyltransferase located in lipid particles and the ER; involved in the stepwise acylation of glycerol-3-phosphate and dihydroxyacetone in lipid biosynthesis" |
| 3462 | YKR068C | BET3 SGDID:S000001776, Chr XI from 570551-569970, reverse complement, Verified ORF, "Hydrophilic protein that acts in conjunction with SNARE proteins in targeting and fusion of ER to Golgi transport vesicles; component of the TRAPP (transport protein particle) complex" |
| 3463 | YKR069W | MET1 SGDID:S000001777, Chr XI from 571254-573035, Verified ORF, "S-adenosyl-L-methionine uroporphyrinogen III transmethylase, involved in the biosynthesis of siroheme, a prosthetic group used by sulfite reductase; required for sulfate assimilation and methionine biosynthesis" |
| 3464 | YKR070W | YKR070W SGDID:S000001778, Chr XI from 573216-574274, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3465 | YKR071C | DRE2 SGDID:S000001779, Chr XI from 575622-574576, reverse complement, Verified ORF, "Protein of unknown function required for sister chromatid cohesion; mutation displays synthetic lethal interaction with the pol3-13 allele of CDC2" |
| 3466 | YKR072C | SIS2 SGDID:S000001780, Chr XI from 577765-576077, reverse complement, Verified ORF, "Negative regulatory subunit of the protein phosphatase 1 Ppz1p; involved in ion homeostasis and cell cycle progression" |
| 3467 | YKR074W | YKR074W SGDID:S000001782, Chr XI from 578851-579318, Uncharacterized ORF, "Putative protein of unknown function; epitope-tagged protein localizes to the cytoplasm; null mutant displays increased frequency of mitochondrial genome loss (petite formation)" |
| 3468 | YKR075C | YKR075C SGDID:S000001783, Chr XI from 580392-579469, reverse complement, Uncharacterized ORF, "Protein of unknown function; similar to YOR062Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS" |
| 3469 | YKR076W | ECM4 SGDID:S000001784, Chr XI from 581925-583037, Verified ORF, "Omega class glutathione transferase; not essential; similar to Ygr154cp; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 3470 | YKR077W | MSA2 SGDID:S000001785, Chr XI from 583295-584386, Uncharacterized ORF, "Putative transcriptional activator, that interacts with G1-specific transcription factor, MBF and G1-specific promoters; ortholog of Msa2p, an MBF and SBF activator that regulates G1-specific transcription and cell cycle initiation" |
| 3471 | YKR078W | YKR078W SGDID:S000001786, Chr XI from 584594-586351, Verified ORF, "Cytoplasmic protein of unknown function, has similarity to Vps5p; potential Cdc28p substrate; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P)" |
| 3472 | YKR079C | TRZ1 SGDID:S000001787, Chr XI from 588947-586431, reverse complement, Verified ORF, "tRNase Z, involved in RNA processing, has two putative nucleotide triphosphate-binding motifs (P-loop) and a conserved histidine motif, homolog of the human candidate prostate cancer susceptibility gene ELAC2" |
| 3473 | YKR080W | MTD1 SGDID:S000001788, Chr XI from 590037-590999, Verified ORF, "NAD-dependent 5,10-methylenetetrahydrafolate dehydrogenase, plays a catalytic role in oxidation of cytoplasmic one-carbon units; expression is regulated by Bas1p and Bas2p, repressed by adenine, and may be induced by inositol and choline" |
| 3474 | YKR081C | RPF2 SGDID:S000001789, Chr XI from 592182-591148, reverse complement, Verified ORF, "Essential protein involved in the processing of pre-rRNA and the assembly of the 60S ribosomal subunit; interacts with ribosomal protein L11; localizes predominantly to the nucleolus; constituent of 66S pre-ribosomal particles" |
| 3475 | YKR082W | NUP133 SGDID:S000001790, Chr XI from 592467-595940, Verified ORF, "Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC), localizes to both sides of the NPC, required to establish a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p" |
| 3476 | YKR083C | DAD2 SGDID:S000001791, Chr XI from 596464-596063, reverse complement, Verified ORF, "Essential subunit of the Dam1 complex (aka DASH complex), couples kinetochores to the force produced by MT depolymerization thereby aiding in chromosome segregation; is transferred to the kinetochore prior to mitosis" |
| 3477 | YKR084C | HBS1 SGDID:S000001792, Chr XI from 598532-596697, reverse complement, Verified ORF, "GTP binding protein with sequence similarity to the elongation factor class of G proteins, EF-1alpha and Sup35p; associates with Dom34p, and shares a similar genetic relationship with genes that encode ribosomal protein components" |
| 3478 | YKR085C | MRPL20 SGDID:S000001793, Chr XI from 599323-598736, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 3479 | YKR086W | PRP16 SGDID:S000001794, Chr XI from 599499-602714, Verified ORF, "RNA helicase in the DEAH-box family involved in the second catalytic step of splicing, exhibits ATP-dependent RNA unwinding activity" |
| 3480 | YKR087C | OMA1 SGDID:S000001795, Chr XI from 603874-602837, reverse complement, Verified ORF, "Metalloendopeptidase of the mitochondrial inner membrane, involved in turnover of membrane-embedded proteins; member of a family of predicted membrane-bound metallopeptidases in prokaryotes and higher eukaryotes" |
| 3481 | YKR088C | TVP38 SGDID:S000001796, Chr XI from 605060-604047, reverse complement, Verified ORF, "Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 3482 | YKR089C | TGL4 SGDID:S000001797, Chr XI from 608007-605275, reverse complement, Verified ORF, "Triacylglycerol lipase involved in triacylglycerol mobilization and degradation; found in lipid particles; potential Cdc28p substrate" |
| 3483 | YKR090W | PXL1 SGDID:S000001798, Chr XI from 608588-610708, Verified ORF, "LIM domain-containing protein that localizes to sites of polarized growth, required for selection and/or maintenance of polarized growth sites, may modulate signaling by the GTPases Cdc42p and Rho1p; has similarity to metazoan paxillin" |
| 3484 | YKR091W | SRL3 SGDID:S000001799, Chr XI from 611167-611907, Verified ORF, "Cytoplasmic protein that, when overexpressed, suppresses the lethality of a rad53 null mutation; potential Cdc28p substrate" |
| 3485 | YKR092C | SRP40 SGDID:S000001800, Chr XI from 613527-612307, reverse complement, Verified ORF, "Nucleolar, serine-rich protein with a role in preribosome assembly or transport; may function as a chaperone of small nucleolar ribonucleoprotein particles (snoRNPs); immunologically and structurally to rat Nopp140" |
| 3486 | YKR093W | PTR2 SGDID:S000001801, Chr XI from 615372-617177, Verified ORF, "Integral membrane peptide transporter, mediates transport of di- and tri-peptides; conserved protein that contains 12 transmembrane domains; PTR2 expression is regulated by the N-end rule pathway via repression by Cup9p" |
| 3487 | YKR094C | RPL40B SGDID:S000001802, Chr XI from 618392-618385,618016-617638, reverse complement, Verified ORF, "Fusion protein, identical to Rpl40Ap, that is cleaved to yield ubiquitin and a ribosomal protein of the large (60S) ribosomal subunit with similarity to rat L40; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes" |
| 3488 | YKR095W | MLP1 SGDID:S000001803, Chr XI from 619447-625074, Verified ORF, "Myosin-like protein associated with the nuclear envelope, connects the nuclear pore complex with the nuclear interior; involved with Tel1p in telomere length control; involved with Pml1p and Pml39p in nuclear retention of unspliced mRNAs" |
| 3489 | YKR095W-A | PCC1 SGDID:S000028512, Chr XI from 625506-625543,625619-625847, Verified ORF, "Proposed transcription factor involved in the expression of genes regulated by alpha-factor and galactose; component of the EKC/KEOPS protein complex with Kae1p, Gon7p, Bud32p, and Cgi121p; related to human cancer-testis antigens" |
| 3490 | YKR096W | YKR096W SGDID:S000001804, Chr XI from 626435-630022, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; predicted to contain a PINc (PilT N terminus) domain" |
| 3491 | YKR097W | PCK1 SGDID:S000001805, Chr XI from 630790-632439, Verified ORF, "Phosphoenolpyruvate carboxykinase, key enzyme in gluconeogenesis, catalyzes early reaction in carbohydrate biosynthesis, glucose represses transcription and accelerates mRNA degradation, regulated by Mcm1p and Cat8p, located in the cytosol" |
| 3492 | YKR098C | UBP11 SGDID:S000001806, Chr XI from 634817-632664, reverse complement, Verified ORF, "Ubiquitin-specific protease that cleaves ubiquitin from ubiquitinated proteins" |
| 3493 | YKR099W | BAS1 SGDID:S000001807, Chr XI from 635489-637924, Verified ORF, "Myb-related transcription factor involved in regulating basal and induced expression of genes of the purine and histidine biosynthesis pathways; also involved in regulation of meiotic recombination at specific genes" |
| 3494 | YKR100C | SKG1 SGDID:S000001808, Chr XI from 639606-638539, reverse complement, Verified ORF, "Transmembrane protein with a role in cell wall polymer composition; localizes on the inner surface of the plasma membrane at the bud and in the daughter cell" |
| 3495 | YKR101W | SIR1 SGDID:S000001809, Chr XI from 640106-642142, Verified ORF, "Protein involved in repression of transcription at the silent mating-type loci HML and HMR; recruitment to silent chromatin requires interactions with Orc1p and with Sir4p, through a common Sir1p domain; binds to centromeric chromatin" |
| 3496 | YKR102W | FLO10 SGDID:S000001810, Chr XI from 645994-649503, Verified ORF, "Lectin-like protein with similarity to Flo1p, thought to be involved in flocculation" |
| 3497 | YKR103W | NFT1 SGDID:S000001811, Chr XI from 652718-656374, Verified ORF, "Putative transporter of the multidrug resistance-associated protein (MRP) subfamily; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds." |
| 3498 | YKR104W | YKR104W SGDID:S000001812, Chr XI from 656474-657394, Verified ORF, "Putative transporter of the multidrug resistance-associated protein (MRP) subfamily; contains a stop codon in S288C; adjacent ORFs YKR103W and YKR104W are merged in different strain backgrounds" |
| 3499 | YKR105C | VBA5 SGDID:S000001813, Chr XI from 660102-658354, reverse complement, Uncharacterized ORF, "Putative transporter of the Major Facilitator Superfamily (MFS); proposed role as a basic amino acid permease based on phylogeny" |
| 3500 | YKR106W | YKR106W SGDID:S000001814, Chr XI from 661080-662927, Uncharacterized ORF, "Protein of unconfirmed function; displays a topology characteristic of the Major Facilitators Superfamily of membrane proteins; coding sequence 98% identical to that of YCL073C" |
| 3501 | YLL001W | DNM1 SGDID:S000003924, Chr XII from 147889-150162, Verified ORF, "Dynamin-related GTPase required for mitochondrial fission and the maintenance of mitochondrial morphology, assembles on the cytoplasmic face of mitochondrial tubules at sites at which division will occur; also participates in endocytosis" |
| 3502 | YLL002W | RTT109 SGDID:S000003925, Chr XII from 146290-147600, Verified ORF, "Histone acetyltransferase critical for cell survival in the presence of DNA damage during S phase, acetylates H3-K56; plays a role in regulation of Ty1 transposition" |
| 3503 | YLL003W | SFI1 SGDID:S000003926, Chr XII from 143200-146040, Verified ORF, "Centrin (Cdc31p)-binding protein required for spindle pole body (SPB) duplication, localizes to the half-bridge of the SPB, required for progression through G(2)-M transition, has similarity to Xenopus laevis XCAP-C" |
| 3504 | YLL004W | ORC3 SGDID:S000003927, Chr XII from 141072-142922, Verified ORF, "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing" |
| 3505 | YLL005C | SPO75 SGDID:S000003928, Chr XII from 140545-137939, reverse complement, Verified ORF, "Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis" |
| 3506 | YLL006W | MMM1 SGDID:S000003929, Chr XII from 136585-137865, Verified ORF, "Mitochondrial outer membrane protein, component of the Mdm10-Mdm12-Mmm1 complex involved in import and assembly of outer membrane beta-barrel proteins" |
| 3507 | YLL006W-A | YLL006W-A SGDID:S000028560, Chr XII from 136344-136520, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 3508 | YLL007C | YLL007C SGDID:S000003930, Chr XII from 136298-134301, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLL007C is not an essential gene" |
| 3509 | YLL008W | DRS1 SGDID:S000003931, Chr XII from 131728-133986, Verified ORF, "Nucleolar DEAD-box protein required for ribosome assembly and function, including synthesis of 60S ribosomal subunits; constituent of 66S pre-ribosomal particles" |
| 3510 | YLL009C | COX17 SGDID:S000003932, Chr XII from 131413-131204, reverse complement, Verified ORF, "Copper metallochaperone that transfers copper to Sco1p and Cox11p for eventual delivery to cytochrome c oxidase" |
| 3511 | YLL010C | PSR1 SGDID:S000003933, Chr XII from 130612-129329, reverse complement, Verified ORF, "Plasma membrane associated protein phosphatase involved in the general stress response; required along with binding partner Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p" |
| 3512 | YLL011W | SOF1 SGDID:S000003934, Chr XII from 127522-128991, Verified ORF, "Essential protein required for biogenesis of 40S (small) ribosomal subunit; has similarity to the beta subunit of trimeric G-proteins and the splicing factor Prp4p" |
| 3513 | YLL012W | YEH1 SGDID:S000003935, Chr XII from 125533-127254, Verified ORF, "Steryl ester hydrolase, one of three gene products (Yeh1p, Yeh2p, Tgl1p) responsible for steryl ester hydrolase activity and involved in sterol homeostasis; localized to lipid particle membranes" |
| 3514 | YLL013C | PUF3 SGDID:S000003936, Chr XII from 124713-122074, reverse complement, Verified ORF, "Protein of the mitochondrial outer surface, links the Arp2/3 complex with the mitochore during anterograde mitochondrial movement; also binds to and promotes degradation of mRNAs for select nuclear-encoded mitochondrial proteins" |
| 3515 | YLL014W | YLL014W SGDID:S000003937, Chr XII from 121321-121647, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YLL014W is not an essential gene" |
| 3516 | YLL015W | BPT1 SGDID:S000003938, Chr XII from 116431-121110, Verified ORF, "ABC type transmembrane transporter of MRP/CFTR family, found in vacuolar membrane, involved in the transport of unconjugated bilirubin and in heavy metal detoxification via glutathione conjugates, along with Ycf1p" |
| 3517 | YLL018C | DPS1 SGDID:S000003941, Chr XII from 111574-109901, reverse complement, Verified ORF, "Cytoplasmic aspartyl-tRNA synthetase, homodimeric enzyme that catalyzes the specific aspartylation of tRNA(Asp); class II aminoacyl tRNA synthetase; binding to its own mRNA may confer autoregulation" |
| 3518 | YLL018C-A | COX19 SGDID:S000007245, Chr XII from 108971-108675, reverse complement, Verified ORF, "Protein required for cytochrome c oxidase assembly, located in the cytosol and mitochondrial intermembrane space; putative copper metallochaperone that delivers copper to cytochrome c oxidase" |
| 3519 | YLL019C | KNS1 SGDID:S000003942, Chr XII from 107898-105685, reverse complement, Verified ORF, "Nonessential putative protein kinase of unknown cellular role; member of the LAMMER family of protein kinases, which are serine/threonine kinases also capable of phosphorylating tyrosine residues" |
| 3520 | YLL021W | SPA2 SGDID:S000003944, Chr XII from 100946-105346, Verified ORF, "Component of the polarisome, which functions in actin cytoskeletal organization during polarized growth; acts as a scaffold for Mkk1p and Mpk1p cell wall integrity signaling components; potential Cdc28p substrate" |
| 3521 | YLL022C | HIF1 SGDID:S000003945, Chr XII from 100200-99043, reverse complement, Verified ORF, "Non-essential component of the HAT-B histone acetyltransferase complex (Hat1p-Hat2p-Hif1p), localized to the nucleus; has a role in telomeric silencing" |
| 3522 | YLL023C | YLL023C SGDID:S000003946, Chr XII from 98835-97996, reverse complement, Verified ORF, "Protein of unknown function; highly conserved across species and orthologous to human TMEM33; may interact with ribosomes, based on co-purification experiments; GFP-fusion protein localizes to the endoplasmic reticulum" |
| 3523 | YLL024C | SSA2 SGDID:S000003947, Chr XII from 97484-95565, reverse complement, Verified ORF, "ATP binding protein involved in protein folding and vacuolar import of proteins; member of heat shock protein 70 (HSP70) family; associated with the chaperonin-containing T-complex; present in the cytoplasm, vacuolar membrane and cell wall" |
| 3524 | YLL025W | YLL025W SGDID:S000003948, Chr XII from 94746-95120, Uncharacterized ORF, "Putative protein of unknown function; YLL025W is not an essential gene" |
| 3525 | YLL026W | HSP104 SGDID:S000003949, Chr XII from 88622-91348, Verified ORF, "Heat shock protein that cooperates with Ydj1p (Hsp40) and Ssa1p (Hsp70) to refold and reactivate previously denatured, aggregated proteins; responsive to stresses including: heat, ethanol, and sodium arsenite; involved in [PSI+] propagation" |
| 3526 | YLL027W | ISA1 SGDID:S000003950, Chr XII from 87402-88154, Verified ORF, "Mitochondrial matrix protein involved in biogenesis of the iron-sulfur (Fe/S) cluster of Fe/S proteins, isa1 deletion causes loss of mitochondrial DNA and respiratory deficiency; depletion reduces growth on nonfermentable carbon sources" |
| 3527 | YLL028W | TPO1 SGDID:S000003951, Chr XII from 84803-86563, Verified ORF, "Polyamine transporter that recognizes spermine, putrescine, and spermidine; catalyzes uptake of polyamines at alkaline pH and excretion at acidic pH; phosphorylation enhances activity and sorting to the plasma membrane" |
| 3528 | YLL029W | FRA1 SGDID:S000003952, Chr XII from 81460-83709, Verified ORF, "Protein involved in negative regulation of transcription of iron regulon; forms an iron independent complex with Fra2p, Grx3p, and Grx4p; cytosolic; mutant fails to repress transcription of iron regulon and is defective in spore formation" |
| 3529 | YLL031C | GPI13 SGDID:S000003954, Chr XII from 80204-77151, reverse complement, Verified ORF, "ER membrane localized phosphoryltransferase that adds phosphoethanolamine onto the third mannose residue of the glycosylphosphatidylinositol (GPI) anchor precursor; similar to human PIG-O protein" |
| 3530 | YLL032C | YLL032C SGDID:S000003955, Chr XII from 76746-74269, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLL032C is not an essential gene" |
| 3531 | YLL033W | IRC19 SGDID:S000003956, Chr XII from 73408-74100, Verified ORF, "Putative protein of unknown function; YLL033W is not an essential gene but mutant is defective in spore formation; null mutant displays increased levels of spontaneous Rad52p foci" |
| 3532 | YLL034C | RIX7 SGDID:S000003957, Chr XII from 73145-70632, reverse complement, Verified ORF, "Putative ATPase of the AAA family, required for export of pre-ribosomal large subunits from the nucleus; distributed between the nucleolus, nucleoplasm, and nuclear periphery depending on growth conditions" |
| 3533 | YLL035W | GRC3 SGDID:S000003958, Chr XII from 68579-70477, Verified ORF, "Protein of unknown function, required for cell growth and possibly involved in rRNA processing; mRNA is cell cycle regulated" |
| 3534 | YLL036C | PRP19 SGDID:S000003959, Chr XII from 68255-66744, reverse complement, Verified ORF, "Splicing factor associated with the spliceosome; contains a U-box, a motif found in a class of ubiquitin ligases" |
| 3535 | YLL038C | ENT4 SGDID:S000003961, Chr XII from 66517-65774, reverse complement, Verified ORF, "Protein of unknown function, contains an N-terminal epsin-like domain" |
| 3536 | YLL039C | UBI4 SGDID:S000003962, Chr XII from 65206-64061, reverse complement, Verified ORF, "Ubiquitin, becomes conjugated to proteins, marking them for selective degradation via the ubiquitin-26S proteasome system; essential for the cellular stress response; encoded as a polyubiquitin precursor comprised of 5 head-to-tail repeats" |
| 3537 | YLL040C | VPS13 SGDID:S000003963, Chr XII from 63644-54210, reverse complement, Verified ORF, "Protein of unknown function; heterooligomeric or homooligomeric complex; peripherally associated with membranes; homologous to human COH1; involved in sporulation, vacuolar protein sorting and protein-Golgi retention" |
| 3538 | YLL041C | SDH2 SGDID:S000003964, Chr XII from 53930-53130, reverse complement, Verified ORF, "Iron-sulfur protein subunit of succinate dehydrogenase (Sdh1p, Sdh2p, Sdh3p, Sdh4p), which couples the oxidation of succinate to the transfer of electrons to ubiquinone" |
| 3539 | YLL042C | ATG10 SGDID:S000003965, Chr XII from 52589-52086, reverse complement, Verified ORF, "E2-like conjugating enzyme that mediates formation of the Atg12p-Atg5p conjugate, which is a critical step in autophagy" |
| 3540 | YLL043W | FPS1 SGDID:S000003966, Chr XII from 49937-51946, Verified ORF, "Plasma membrane channel, member of major intrinsic protein (MIP) family; involved in efflux of glycerol and in uptake of acetic acid and the trivalent metalloids arsenite and antimonite; phosphorylated by Hog1p MAPK under acetate stress" |
| 3541 | YLL045C | RPL8B SGDID:S000003968, Chr XII from 48628-47858, reverse complement, Verified ORF, "Ribosomal protein L4 of the large (60S) ribosomal subunit, nearly identical to Rpl8Ap and has similarity to rat L7a ribosomal protein; mutation results in decreased amounts of free 60S subunits" |
| 3542 | YLL046C | RNP1 SGDID:S000003969, Chr XII from 47462-46713, reverse complement, Verified ORF, "Ribonucleoprotein that contains two RNA recognition motifs (RRM)" |
| 3543 | YLL048C | YBT1 SGDID:S000003971, Chr XII from 46264-41279, reverse complement, Verified ORF, "Transporter of the ATP-binding cassette (ABC) family involved in bile acid transport; similar to mammalian bile transporters" |
| 3544 | YLL049W | LDB18 SGDID:S000003972, Chr XII from 40665-41204, Verified ORF, "Protein of unknown function; null mutant shows a reduced affinity for the alcian blue dye suggesting a decreased net negative charge of the cell surface" |
| 3545 | YLL050C | COF1 SGDID:S000003973, Chr XII from 40413-40400,40220-39803, reverse complement, Verified ORF, "Cofilin, promotes actin filament depolarization in a pH-dependent manner; binds both actin monomers and filaments and severs filaments; thought to be regulated by phosphorylation at SER4; ubiquitous and essential in eukaryotes" |
| 3546 | YLL051C | FRE6 SGDID:S000003974, Chr XII from 39470-37332, reverse complement, Verified ORF, "Putative ferric reductase with similarity to Fre2p; expression induced by low iron levels" |
| 3547 | YLL052C | AQY2 SGDID:S000003975, Chr XII from 36360-35911, reverse complement, Verified ORF, "Water channel that mediates the transport of water across cell membranes, only expressed in proliferating cells, controlled by osmotic signals, may be involved in freeze tolerance; disrupted by a stop codon in many S. cerevisiae strains" |
| 3548 | YLL053C | YLL053C SGDID:S000003976, Chr XII from 35960-35502, reverse complement, Uncharacterized ORF, "Putative protein; in the Sigma 1278B strain background YLL053C is contiguous with AQY2 which encodes an aquaporin" |
| 3549 | YLL054C | YLL054C SGDID:S000003977, Chr XII from 35203-32894, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with similarity to Pip2p, an oleate-specific transcriptional activator of peroxisome proliferation; YLL054C is not an essential gene" |
| 3550 | YLL055W | YCT1 SGDID:S000003978, Chr XII from 30109-31704, Verified ORF, "High-affinity cysteine-specific transporter with similarity to the Dal5p family of transporters; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YCT1 is not an essential gene" |
| 3551 | YLL056C | YLL056C SGDID:S000003979, Chr XII from 28305-27409, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in pleiotropic drug resistance (PDR) phenomenon; YLL056C is not an essential gene" |
| 3552 | YLL057C | JLP1 SGDID:S000003980, Chr XII from 26994-25756, reverse complement, Verified ORF, "Fe(II)-dependent sulfonate/alpha-ketoglutarate dioxygenase, involved in sulfonate catabolism for use as a sulfur source, contains sequence that closely resembles a J domain (typified by the E. coli DnaJ protein)" |
| 3553 | YLL058W | YLL058W SGDID:S000003981, Chr XII from 23569-25296, Uncharacterized ORF, "Putative protein of unknown function with similarity to Str2p, which is a cystathionine gamma-synthase important in sulfur metabolism; YLL058W is not an essential gene" |
| 3554 | YLL060C | GTT2 SGDID:S000003983, Chr XII from 21839-21138, reverse complement, Verified ORF, "Glutathione S-transferase capable of homodimerization; functional overlap with Gtt2p, Grx1p, and Grx2p" |
| 3555 | YLL061W | MMP1 SGDID:S000003984, Chr XII from 17956-19707, Verified ORF, "High-affinity S-methylmethionine permease, required for utilization of S-methylmethionine as a sulfur source; has similarity to S-adenosylmethionine permease Sam3p" |
| 3556 | YLL062C | MHT1 SGDID:S000003985, Chr XII from 17613-16639, reverse complement, Verified ORF, "S-methylmethionine-homocysteine methyltransferase, functions along with Sam4p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio" |
| 3557 | YLL063C | AYT1 SGDID:S000003986, Chr XII from 16072-14648, reverse complement, Verified ORF, "Acetyltransferase; catalyzes trichothecene 3-O-acetylation, suggesting a possible role in trichothecene biosynthesis" |
| 3558 | YLL064C | YLL064C SGDID:S000003987, Chr XII from 13445-13083, reverse complement, Uncharacterized ORF, "Hypothetical protein" |
| 3559 | YLL066C | YLL066C SGDID:S000003989, Chr XII from 9836-9550,9450-6120, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with similarity to helicases; YLL066C is not an essential gene" |
| 3560 | YLL066W-B | YLL066W-B SGDID:S000028672, Chr XII from 5605-5775, Uncharacterized ORF, "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" |
| 3561 | YLL067C | YLL067C SGDID:S000003990, Chr XII from 4301-4015,3915-585, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with similarity to helicases" |
| 3562 | YLR001C | YLR001C SGDID:S000003991, Chr XII from 153976-151388, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YLR001C is not an essential gene" |
| 3563 | YLR002C | NOC3 SGDID:S000003992, Chr XII from 156333-154342, reverse complement, Verified ORF, "Protein that forms a nuclear complex with Noc2p that binds to 66S ribosomal precursors to mediate their intranuclear transport; also binds to chromatin to promote the association of DNA replication factors and replication initiation" |
| 3564 | YLR003C | YLR003C SGDID:S000003993, Chr XII from 157729-156854, reverse complement, Uncharacterized ORF, "Putative protein of unknown function that may participate in DNA replication; green fluorescent protein (GFP)-fusion protein is localized to the nucleus; YLR003C is not an essential gene" |
| 3565 | YLR004C | THI73 SGDID:S000003994, Chr XII from 159504-157933, reverse complement, Verified ORF, "Putative plasma membrane permease proposed to be involved in carboxylic acid uptake and repressed by thiamine; substrate of Dbf2p/Mob1p kinase; transcription is altered if mitochondrial dysfunction occurs" |
| 3566 | YLR005W | SSL1 SGDID:S000003995, Chr XII from 160048-161433, Verified ORF, "Component of the core form of RNA polymerase transcription factor TFIIH, which has both protein kinase and DNA-dependent ATPase/helicase activities and is essential for transcription and nucleotide excision repair; interacts with Tfb4p" |
| 3567 | YLR006C | SSK1 SGDID:S000003996, Chr XII from 163892-161754, reverse complement, Verified ORF, "Cytoplasmic response regulator, part of a two-component signal transducer that mediates osmosensing via a phosphorelay mechanism; dephosphorylated form is degraded by the ubiquitin-proteasome system; potential Cdc28p substrate" |
| 3568 | YLR007W | NSE1 SGDID:S000003997, Chr XII from 164391-165401, Verified ORF, "Essential subunit of the Mms21-Smc5-Smc6 complex; nuclear protein required for DNA repair and growth; has a nonstructural role in the maintenance of chromosomes" |
| 3569 | YLR008C | PAM18 SGDID:S000003998, Chr XII from 166082-165576, reverse complement, Verified ORF, "J-protein co-chaperone of the mitochondrial import motor associated with the presequence translocase, with Ssc1p, Tim44p, Mge1p, and Pam16p; stimulates ATPase activity of Ssc1p to drive mitochondrial import; activity is inhibited by Pam16p" |
| 3570 | YLR009W | RLP24 SGDID:S000003999, Chr XII from 166536-167135, Verified ORF, "Essential protein with similarity to Rpl24Ap and Rpl24Bp, associated with pre-60S ribosomal subunits and required for ribosomal large subunit biogenesis" |
| 3571 | YLR010C | TEN1 SGDID:S000004000, Chr XII from 167801-167319, reverse complement, Verified ORF, "Protein that regulates telomeric length; protects telomeric ends in a complex with Cdc13p and Stn1p" |
| 3572 | YLR011W | LOT6 SGDID:S000004001, Chr XII from 169102-169677, Verified ORF, "FMN-dependent NAD(P)H:quinone reductase that may be involved in quinone detoxification; gene expression increases in cultures shifted to a lower temperature" |
| 3573 | YLR012C | YLR012C SGDID:S000004002, Chr XII from 170280-169981, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YLR012C is not an essential gene" |
| 3574 | YLR013W | GAT3 SGDID:S000004003, Chr XII from 171338-171763, Verified ORF, "Protein containing GATA family zinc finger motifs" |
| 3575 | YLR014C | PPR1 SGDID:S000004004, Chr XII from 174981-172267, reverse complement, Verified ORF, "Zinc finger transcription factor containing a Zn(2)-Cys(6) binuclear cluster domain, positively regulates transcription of genes involved in uracil biosynthesis; activity may be modulated by interaction with Tup1p" |
| 3576 | YLR015W | BRE2 SGDID:S000004005, Chr XII from 175226-176743, Verified ORF, "Subunit of the COMPASS (Set1C) complex, which methylates histone H3 on lysine 4 and is required in transcriptional silencing near telomeres; involved in telomere maintenance; similar to trithorax-group protein ASH2L" |
| 3577 | YLR016C | PML1 SGDID:S000004006, Chr XII from 177415-176801, reverse complement, Verified ORF, "Subunit of the RES complex, which is required for nuclear retention of unspliced pre-mRNAs; acts in the same pathway as Pml39p and Mlp1p" |
| 3578 | YLR017W | MEU1 SGDID:S000004007, Chr XII from 177607-178620, Verified ORF, "Methylthioadenosine phosphorylase (MTAP), catalyzes the initial step in the methionine salvage pathway; affects polyamine biosynthesis through regulation of ornithine decarboxylase (Spe1p) activity; regulates ADH2 gene expression" |
| 3579 | YLR018C | POM34 SGDID:S000004008, Chr XII from 179605-178706, reverse complement, Verified ORF, "Integral membrane protein of the nuclear pore; has an important role in maintaining the architecture of the pore complex" |
| 3580 | YLR019W | PSR2 SGDID:S000004009, Chr XII from 180287-181480, Verified ORF, "Functionally redundant Psr1p homolog, a plasma membrane phosphatase involved in the general stress response; required with Psr1p and Whi2p for full activation of STRE-mediated gene expression, possibly through dephosphorylation of Msn2p" |
| 3581 | YLR020C | YEH2 SGDID:S000004010, Chr XII from 183404-181788, reverse complement, Verified ORF, "Steryl ester hydrolase, catalyzes steryl ester hydrolysis at the plasma membrane; involved in sterol metabolism" |
| 3582 | YLR021W | IRC25 SGDID:S000004011, Chr XII from 183622-184161, Verified ORF, "Component of a heterodimeric Poc4p-Irc25p chaperone involved in assembly of alpha subunits into the 20S proteasome; may regulate formation of proteasome isoforms with alternative subunits under different conditions" |
| 3583 | YLR022C | SDO1 SGDID:S000004012, Chr XII from 184925-184173, reverse complement, Verified ORF, "Essential protein involved in 60S ribosome maturation; ortholog of the human protein (SBDS) responsible for autosomal recessive Shwachman-Bodian-Diamond Syndrome; highly conserved across archae and eukaryotes" |
| 3584 | YLR023C | IZH3 SGDID:S000004013, Chr XII from 187128-185497, reverse complement, Verified ORF, "Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by zinc deficiency; deletion reduces sensitivity to elevated zinc and shortens lag phase, overexpression reduces Zap1p activity" |
| 3585 | YLR024C | UBR2 SGDID:S000004014, Chr XII from 193282-187664, reverse complement, Verified ORF, "Cytoplasmic ubiquitin-protein ligase (E3)" |
| 3586 | YLR025W | SNF7 SGDID:S000004015, Chr XII from 194453-195175, Verified ORF, "One of four subunits of the endosomal sorting complex required for transport III (ESCRT-III); involved in the sorting of transmembrane proteins into the multivesicular body (MVB) pathway; recruited from the cytoplasm to endosomal membranes" |
| 3587 | YLR026C | SED5 SGDID:S000004016, Chr XII from 196473-195451, reverse complement, Verified ORF, "cis-Golgi t-SNARE syntaxin required for vesicular transport between the ER and the Golgi complex, binds at least 9 SNARE proteins" |
| 3588 | YLR027C | AAT2 SGDID:S000004017, Chr XII from 198086-196830, reverse complement, Verified ORF, "Cytosolic aspartate aminotransferase, involved in nitrogen metabolism; localizes to peroxisomes in oleate-grown cells" |
| 3589 | YLR028C | ADE16 SGDID:S000004018, Chr XII from 201316-199541, reverse complement, Verified ORF, "Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade17p; ade16 ade17 mutants require adenine and histidine" |
| 3590 | YLR029C | RPL15A SGDID:S000004019, Chr XII from 202591-201977, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Bp and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA" |
| 3591 | YLR030W | YLR030W SGDID:S000004020, Chr XII from 203291-204082, Uncharacterized ORF, "Putative protein of unknown function" |
| 3592 | YLR031W | YLR031W SGDID:S000004021, Chr XII from 204226-204786, Uncharacterized ORF, "Putative protein of unknown function" |
| 3593 | YLR032W | RAD5 SGDID:S000004022, Chr XII from 204992-208501, Verified ORF, "DNA helicase proposed to promote replication fork regression during postreplication repair by template switching; contains RING finger domain" |
| 3594 | YLR033W | RSC58 SGDID:S000004023, Chr XII from 208762-210270, Verified ORF, "Component of the RSC chromatin remodeling complex; RSC functions in transcriptional regulation and elongation, chromosome stability, and establishing sister chromatid cohesion; involved in telomere maintenance58KDa subunit" |
| 3595 | YLR034C | SMF3 SGDID:S000004024, Chr XII from 211934-210513, reverse complement, Verified ORF, "Putative divalent metal ion transporter involved in iron homeostasis; transcriptionally regulated by metal ions; member of the Nramp family of metal transport proteins" |
| 3596 | YLR035C | MLH2 SGDID:S000004025, Chr XII from 214457-212370, reverse complement, Verified ORF, "Protein involved in the mismatch repair of certain frameshift intermediates and involved in meiotic recombination; forms a complex with Mlh1p" |
| 3597 | YLR035C-A | YLR035C-A SGDID:S000007225, Chr XII from 218908-215441, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); YLR035C-A is part of a mutant retrotransposon" |
| 3598 | YLR036C | YLR036C SGDID:S000004026, Chr XII from 222133-221522, reverse complement, Uncharacterized ORF, "Putative protein of unknown function predicted to have transmembrane domains; interacts with HSP90 by yeast two-hybrid analysis; YLR036C is not an essential protein" |
| 3599 | YLR037C | DAN2 SGDID:S000004027, Chr XII from 223060-222686, reverse complement, Verified ORF, "Cell wall mannoprotein with similarity to Tir1p, Tir2p, Tir3p, and Tir4p; expressed under anaerobic conditions, completely repressed during aerobic growth" |
| 3600 | YLR038C | COX12 SGDID:S000004028, Chr XII from 225173-224922, reverse complement, Verified ORF, "Subunit VIb of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; required for assembly of cytochrome c oxidase but not required for activity after assembly; phosphorylated" |
| 3601 | YLR039C | RIC1 SGDID:S000004029, Chr XII from 228597-225427, reverse complement, Verified ORF, "Protein involved in retrograde transport to the cis-Golgi network; forms heterodimer with Rgp1p that acts as a GTP exchange factor for Ypt6p; involved in transcription of rRNA and ribosomal protein genes" |
| 3602 | YLR040C | YLR040C SGDID:S000004030, Chr XII from 229583-228909, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; localizes to the cell wall; predicted to be a GPI-attached protein; upregulated by Mcm1p-Alpha1p transcription factor; partially overlaps the dubious ORF YLR041W; YLR040C is not essential" |
| 3603 | YLR042C | YLR042C SGDID:S000004032, Chr XII from 230452-229967, reverse complement, Uncharacterized ORF, "Protein of unknown function; localizes to the cytoplasm; YLL042C is not an essential gene" |
| 3604 | YLR043C | TRX1 SGDID:S000004033, Chr XII from 232014-231703, reverse complement, Verified ORF, "Cytoplasmic thioredoxin isoenzyme of the thioredoxin system which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa1p, required for ER-Golgi transport and vacuole inheritance" |
| 3605 | YLR044C | PDC1 SGDID:S000004034, Chr XII from 234082-232391, reverse complement, Verified ORF, "Major of three pyruvate decarboxylase isozymes, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde; subject to glucose-, ethanol-, and autoregulation; involved in amino acid catabolism" |
| 3606 | YLR045C | STU2 SGDID:S000004035, Chr XII from 237704-235038, reverse complement, Verified ORF, "Microtubule-associated protein (MAP) of the XMAP215/Dis1 family; regulates microtubule dynamics during spindle orientation and metaphase chromosome alignment; interacts with spindle pole body component Spc72p" |
| 3607 | YLR046C | YLR046C SGDID:S000004036, Chr XII from 238814-238002, reverse complement, Uncharacterized ORF, "Putative membrane protein, transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance" |
| 3608 | YLR047C | FRE8 SGDID:S000004037, Chr XII from 241408-239348, reverse complement, Verified ORF, "Protein with sequence similarity to iron/copper reductases, involved in iron homeostasis; deletion mutant has iron deficiency/accumulation growth defects; expression increased in the absence of copper-responsive transcription factor Mac1p" |
| 3609 | YLR048W | RPS0B SGDID:S000004038, Chr XII from 242233-242322,242682-243350, Verified ORF, "Protein component of the small (40S) ribosomal subunit, nearly identical to Rps0Ap; required for maturation of 18S rRNA along with Rps0Ap; deletion of either RPS0 gene reduces growth rate, deletion of both genes is lethal" |
| 3610 | YLR049C | YLR049C SGDID:S000004039, Chr XII from 245173-243887, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 3611 | YLR050C | YLR050C SGDID:S000004040, Chr XII from 246073-245588, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YLR050C is not an essential gene" |
| 3612 | YLR051C | FCF2 SGDID:S000004041, Chr XII from 246978-246325, reverse complement, Verified ORF, "Essential nucleolar protein involved in the early steps of 35S rRNA processing; interacts with Faf1p; member of a transcriptionally co-regulated set of genes called the RRB regulon" |
| 3613 | YLR052W | IES3 SGDID:S000004042, Chr XII from 247202-247954, Verified ORF, "Subunit of the INO80 chromatin remodeling complex" |
| 3614 | YLR053C | YLR053C SGDID:S000004043, Chr XII from 248427-248101, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 3615 | YLR054C | OSW2 SGDID:S000004044, Chr XII from 250979-250949,250861-248718, reverse complement, Uncharacterized ORF, "Protein of unknown function proposed to be involved in the assembly of the spore wall" |
| 3616 | YLR055C | SPT8 SGDID:S000004045, Chr XII from 253081-251273, reverse complement, Verified ORF, "Subunit of the SAGA transcriptional regulatory complex but not present in SAGA-like complex SLIK/SALSA, required for SAGA-mediated inhibition at some promoters" |
| 3617 | YLR056W | ERG3 SGDID:S000004046, Chr XII from 253862-254959, Verified ORF, "C-5 sterol desaturase, catalyzes the introduction of a C-5(6) double bond into episterol, a precursor in ergosterol biosynthesis; mutants are viable, but cannot grow on non-fermentable carbon sources" |
| 3618 | YLR057W | YLR057W SGDID:S000004047, Chr XII from 255307-257856, Uncharacterized ORF, "Putative protein of unknown function; YLR050C is not an essential gene" |
| 3619 | YLR058C | SHM2 SGDID:S000004048, Chr XII from 259402-257993, reverse complement, Verified ORF, "Cytosolic serine hydroxymethyltransferase, converts serine to glycine plus 5,10 methylenetetrahydrofolate; major isoform involved in generating precursors for purine, pyrimidine, amino acid, and lipid biosynthesis" |
| 3620 | YLR059C | REX2 SGDID:S000004049, Chr XII from 260548-259739, reverse complement, Verified ORF, "RNA exonuclease, required for U4 snRNA maturation; functions redundantly with Rnh70p in 5.8S rRNA maturation, and with Rnh70p and Rex3p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases" |
| 3621 | YLR060W | FRS1 SGDID:S000004050, Chr XII from 260980-262767, Verified ORF, "Beta subunit of cytoplasmic phenylalanyl-tRNA synthetase, forms a tetramer with Frs2p to generate active enzyme; sequence is evolutionarily distant from mitochondrial phenylalanyl-tRNA synthetase (Msf1p), but substrate binding is similar" |
| 3622 | YLR061W | RPL22A SGDID:S000004051, Chr XII from 263195-263206,263596-263949, Verified ORF, "Protein component of the large (60S) ribosomal subunit, has similarity to Rpl22Bp and to rat L22 ribosomal protein" |
| 3623 | YLR063W | YLR063W SGDID:S000004053, Chr XII from 264158-265255, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR063W is not an essential gene" |
| 3624 | YLR064W | YLR064W SGDID:S000004054, Chr XII from 265457-266278, Uncharacterized ORF, "Putative protein of unknown function; highly conserved across species and orthologous to human TMEM33; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YLR064W is not an essential gene" |
| 3625 | YLR065C | YLR065C SGDID:S000004055, Chr XII from 266919-266374, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YLR065C is not an essential gene" |
| 3626 | YLR066W | SPC3 SGDID:S000004056, Chr XII from 267170-267724, Verified ORF, "Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC22/23" |
| 3627 | YLR067C | PET309 SGDID:S000004057, Chr XII from 270711-267814, reverse complement, Verified ORF, "Specific translational activator for the COX1 mRNA, also influences stability of intron-containing COX1 primary transcripts; located in the mitochondrial inner membrane" |
| 3628 | YLR068W | FYV7 SGDID:S000004058, Chr XII from 271009-271464, Verified ORF, "Protein of unknown function, required for survival upon exposure to K1 killer toxin; involved in processing the 35S rRNA primary transcript to generate the 20S and 27SA2 pre-rRNA transcripts" |
| 3629 | YLR069C | MEF1 SGDID:S000004059, Chr XII from 273916-271631, reverse complement, Verified ORF, "Mitochondrial elongation factor involved in translational elongation" |
| 3630 | YLR070C | XYL2 SGDID:S000004060, Chr XII from 275212-274142, reverse complement, Verified ORF, "Xylitol dehydrogenase, converts xylitol to D-xylulose in the endogenous xylose utilization pathway" |
| 3631 | YLR071C | RGR1 SGDID:S000004061, Chr XII from 278627-275379, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for glucose repression, HO repression, RME1 repression and sporulation" |
| 3632 | YLR072W | YLR072W SGDID:S000004062, Chr XII from 278863-280944, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YLR072W is not an esssential gene" |
| 3633 | YLR073C | YLR073C SGDID:S000004063, Chr XII from 281622-281020, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to endosomes; YLR073C is not an esssential gene" |
| 3634 | YLR074C | BUD20 SGDID:S000004064, Chr XII from 282457-281957, reverse complement, Verified ORF, "Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern" |
| 3635 | YLR075W | RPL10 SGDID:S000004065, Chr XII from 282928-283593, Verified ORF, "Protein component of the large (60S) ribosomal subunit, responsible for joining the 40S and 60S subunits; regulates translation initiation; has similarity to rat L10 ribosomal protein and to members of the QM gene family" |
| 3636 | YLR077W | YLR077W SGDID:S000004067, Chr XII from 283873-285624, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3637 | YLR078C | BOS1 SGDID:S000004068, Chr XII from 286560-286558,286468-285737, reverse complement, Verified ORF, "v-SNARE (vesicle specific SNAP receptor), localized to the endoplasmic reticulum membrane and necessary for vesicular transport from the ER to the Golgi" |
| 3638 | YLR079W | SIC1 SGDID:S000004069, Chr XII from 286821-287675, Verified ORF, "Inhibitor of Cdc28-Clb kinase complexes that controls G1/S phase transition, preventing premature S phase and ensuring genomic integrity; phosphorylation targets Sic1p for SCF(CDC4)-dependent turnover; functional homolog of mammalian Kip1" |
| 3639 | YLR080W | EMP46 SGDID:S000004070, Chr XII from 287917-289251, Verified ORF, "Integral membrane component of endoplasmic reticulum-derived COPII-coated vesicles, which function in ER to Golgi transport" |
| 3640 | YLR081W | GAL2 SGDID:S000004071, Chr XII from 290213-291937, Verified ORF, "Galactose permease, required for utilization of galactose; also able to transport glucose" |
| 3641 | YLR082C | SRL2 SGDID:S000004072, Chr XII from 293573-292395, reverse complement, Verified ORF, "Protein of unknown function; overexpression suppresses the lethality caused by a rad53 null mutation" |
| 3642 | YLR083C | EMP70 SGDID:S000004073, Chr XII from 296095-294092, reverse complement, Verified ORF, "Protein with a role in cellular adhesion and filamentous growth; similar to Tmn2p and Tmn3p; member of Transmembrane Nine family of proteins with 9 transmembrane segments; 24kDa cleavage product found in endosome-enriched membrane fractions" |
| 3643 | YLR084C | RAX2 SGDID:S000004074, Chr XII from 300252-296590, reverse complement, Verified ORF, "N-glycosylated protein involved in the maintenance of bud site selection during bipolar budding; localization requires Rax1p" |
| 3644 | YLR085C | ARP6 SGDID:S000004075, Chr XII from 301990-300674, reverse complement, Verified ORF, "Actin-related protein that binds nucleosomes; a component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A" |
| 3645 | YLR086W | SMC4 SGDID:S000004076, Chr XII from 302244-306500, Verified ORF, "Subunit of the condensin complex, which reorganizes chromosomes during cell division, forms a stable complex with Smc2p that has ATP-hydrolyzing and DNA-binding activity and promotes knotting of circular DNA; potential Cdc28p substrate" |
| 3646 | YLR087C | CSF1 SGDID:S000004077, Chr XII from 315732-306856, reverse complement, Verified ORF, "Protein required for fermentation at low temperature; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3647 | YLR088W | GAA1 SGDID:S000004078, Chr XII from 316108-317952, Verified ORF, "Subunit of the GPI (glycosylphosphatidylinositol):protein transamidase complex, removes the GPI-anchoring signal and attaches GPI to proteins in the ER" |
| 3648 | YLR089C | ALT1 SGDID:S000004079, Chr XII from 320016-318238, reverse complement, Uncharacterized ORF, "Putative alanine transaminase (glutamic pyruvic transaminase); the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3649 | YLR090W | XDJ1 SGDID:S000004080, Chr XII from 320702-322081, Verified ORF, "Putative chaperone, homolog of E. coli DnaJ, closely related to Ydj1p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3650 | YLR091W | YLR091W SGDID:S000004081, Chr XII from 322298-323179, Uncharacterized ORF, "Protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YLR091W is not an esssential gene" |
| 3651 | YLR092W | SUL2 SGDID:S000004082, Chr XII from 323545-326226, Verified ORF, "High affinity sulfate permease; sulfate uptake is mediated by specific sulfate transporters Sul1p and Sul2p, which control the concentration of endogenous activated sulfate intermediates" |
| 3652 | YLR093C | NYV1 SGDID:S000004083, Chr XII from 327416-327401,327259-326514, reverse complement, Verified ORF, "v-SNARE component of the vacuolar SNARE complex involved in vesicle fusion; inhibits ATP-dependent Ca(2+) transport activity of Pmc1p in the vacuolar membrane" |
| 3653 | YLR094C | GIS3 SGDID:S000004084, Chr XII from 329239-327731, reverse complement, Verified ORF, "Protein of unknown function" |
| 3654 | YLR095C | IOC2 SGDID:S000004085, Chr XII from 332116-329678, reverse complement, Verified ORF, "Member of a complex (Isw1b) with Isw1p and Ioc4p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing, contains a PHD finger motif" |
| 3655 | YLR096W | KIN2 SGDID:S000004086, Chr XII from 332591-336034, Verified ORF, "Serine/threonine protein kinase involved in regulation of exocytosis; localizes to the cytoplasmic face of the plasma membrane; closely related to Kin1p" |
| 3656 | YLR097C | HRT3 SGDID:S000004087, Chr XII from 337266-336232, reverse complement, Verified ORF, "Putative SCF-ubiquitin ligase F-box protein, based on both genetic and physical interactions and sequence similarity; identified in association with Cdc53p, Skp1p and Ubi4 in large and small-scale studies" |
| 3657 | YLR098C | CHA4 SGDID:S000004088, Chr XII from 339474-337528, reverse complement, Verified ORF, "DNA binding transcriptional activator, mediates serine/threonine activation of the catabolic L-serine (L-threonine) deaminase (CHA1); Zinc-finger protein with Zn[2]-Cys[6] fungal-type binuclear cluster domain" |
| 3658 | YLR099C | ICT1 SGDID:S000004089, Chr XII from 340929-339745, reverse complement, Verified ORF, "Lysophosphatidic acid acyltransferase, responsible for enhanced phospholipid synthesis during organic solvent stress; null displays increased sensitivity to Calcofluor white; highly expressed during organic solvent stress" |
| 3659 | YLR099W-A | YLR099W-A SGDID:S000007618, Chr XII from 341326-341589, Uncharacterized ORF, "Putative protein of unknown function" |
| 3660 | YLR100W | ERG27 SGDID:S000004090, Chr XII from 341811-342854, Verified ORF, "3-keto sterol reductase, catalyzes the last of three steps required to remove two C-4 methyl groups from an intermediate in ergosterol biosynthesis; mutants are sterol auxotrophs" |
| 3661 | YLR102C | APC9 SGDID:S000004092, Chr XII from 343768-342971, reverse complement, Verified ORF, "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" |
| 3662 | YLR103C | CDC45 SGDID:S000004093, Chr XII from 345942-343990, reverse complement, Verified ORF, "DNA replication initiation factor; recruited to MCM pre-RC complexes at replication origins; promotes release of MCM from Mcm10p, recruits elongation machinery; mutants in human homolog may cause velocardiofacial and DiGeorge syndromes" |
| 3663 | YLR104W | YLR104W SGDID:S000004094, Chr XII from 346586-346981, Uncharacterized ORF, "Putative protein of unknown function; mutant is deficient in amounts of cell wall mannosylphosphate" |
| 3664 | YLR105C | SEN2 SGDID:S000004095, Chr XII from 348181-347048, reverse complement, Verified ORF, "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p; Sen2p contains the active site for tRNA 5' splice site cleavage and has similarity to Sen34p and to Archaeal tRNA splicing endonuclease" |
| 3665 | YLR106C | MDN1 SGDID:S000004096, Chr XII from 363739-349007, reverse complement, Verified ORF, "Huge dynein-related AAA-type ATPase (midasin), forms extended pre-60S particle with the Rix1 complex (Rix1p-Ipi1p-Ipi3p), may mediate ATP-dependent remodeling of 60S subunits and subsequent export from nucleoplasm to cytoplasm" |
| 3666 | YLR107W | REX3 SGDID:S000004097, Chr XII from 364117-365331, Verified ORF, "RNA exonuclease; required for maturation of the RNA component of RNase MRP; functions redundantly with Rnh70p and Rex2p in processing of U5 snRNA and RNase P RNA; member of RNase D family of exonucleases" |
| 3667 | YLR108C | YLR108C SGDID:S000004098, Chr XII from 368125-366668, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YLR108C is not an esssential gene" |
| 3668 | YLR109W | AHP1 SGDID:S000004099, Chr XII from 368782-369312, Verified ORF, "Thiol-specific peroxiredoxin, reduces hydroperoxides to protect against oxidative damage; function in vivo requires covalent conjugation to Urm1p" |
| 3669 | YLR110C | CCW12 SGDID:S000004100, Chr XII from 370099-369698, reverse complement, Verified ORF, "Cell wall mannoprotein, mutants are defective in mating and agglutination, expression is downregulated by alpha-factor" |
| 3670 | YLR113W | HOG1 SGDID:S000004103, Chr XII from 371621-372928, Verified ORF, "Mitogen-activated protein kinase involved in osmoregulation via three independent osmosensors; mediates the recruitment and activation of RNA Pol II at Hot1p-dependent promoters; localization regulated by Ptp2p and Ptp3p" |
| 3671 | YLR114C | AVL9 SGDID:S000004104, Chr XII from 377239-374945, reverse complement, Verified ORF, "Conserved protein involved in exocytic transport from the Golgi; mutation is synthetically lethal with apl2 vps1 double mutation; member of a protein superfamily with orthologs in diverse organisms" |
| 3672 | YLR115W | CFT2 SGDID:S000004105, Chr XII from 377986-380565, Verified ORF, "Subunit of the mRNA cleavage and polyadenlylation factor (CPF); required for pre-mRNA cleavage, polyadenylation and poly(A) site recognition, 43% similarity with the mammalian CPSF-100 protein." |
| 3673 | YLR116W | MSL5 SGDID:S000004106, Chr XII from 380823-382253, Verified ORF, "Component of the commitment complex, which defines the first step in the splicing pathway; essential protein that interacts with Mud2p and Prp40p, forming a bridge between the intron ends; also involved in nuclear retention of pre-mRNA" |
| 3674 | YLR117C | CLF1 SGDID:S000004107, Chr XII from 384535-382472, reverse complement, Verified ORF, "Essential splicesome assembly factor; contains multiple tetratricopeptide repeat (TPR) protein-binding motifs and interacts specifically with many spliceosome components, may serve as a scaffold during splicesome assembly" |
| 3675 | YLR118C | YLR118C SGDID:S000004108, Chr XII from 385409-384726, reverse complement, Verified ORF, "Acyl-protein thioesterase responsible for depalmitoylation of Gpa1p; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced in response to the DNA-damaging agent MMS" |
| 3676 | YLR119W | SRN2 SGDID:S000004109, Chr XII from 385535-386176, Verified ORF, "Component of the ESCRT-I complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; suppressor of rna1-1 mutation; may be involved in RNA export from nucleus" |
| 3677 | YLR120C | YPS1 SGDID:S000004110, Chr XII from 388221-386512, reverse complement, Verified ORF, "Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" |
| 3678 | YLR121C | YPS3 SGDID:S000004111, Chr XII from 390271-388745, reverse complement, Verified ORF, "Aspartic protease, attached to the plasma membrane via a glycosylphosphatidylinositol (GPI) anchor" |
| 3679 | YLR125W | YLR125W SGDID:S000004115, Chr XII from 393485-393895, Uncharacterized ORF, "Putative protein of unknown function; mutant has decreased Ty3 transposition; YLR125W is not an essential gene" |
| 3680 | YLR126C | YLR126C SGDID:S000004116, Chr XII from 395521-394766, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with similarity to glutamine amidotransferase proteins; has Aft1p-binding motif in the promoter; may be involved in copper and iron homeostasis; YLR126C is not an essential protein" |
| 3681 | YLR127C | APC2 SGDID:S000004117, Chr XII from 398320-395759, reverse complement, Verified ORF, "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition; similar to cullin Cdc53p" |
| 3682 | YLR128W | DCN1 SGDID:S000004118, Chr XII from 398531-398533,398628-399434, Verified ORF, "Putative Nedd8 ligase; binds Nedd8; involved in cullin neddylation; not essential; similar to C.elegans DCN-1; contains UBA-like ubiquitin-binding domain and a DUF298 domain" |
| 3683 | YLR129W | DIP2 SGDID:S000004119, Chr XII from 399658-402489, Verified ORF, "Nucleolar protein, specifically associated with the U3 snoRNA, part of the large ribonucleoprotein complex known as the small subunit (SSU) processome, required for 18S rRNA biogenesis, part of the active pre-rRNA processing complex" |
| 3684 | YLR130C | ZRT2 SGDID:S000004120, Chr XII from 404063-402795, reverse complement, Verified ORF, "Low-affinity zinc transporter of the plasma membrane; transcription is induced under low-zinc conditions by the Zap1p transcription factor" |
| 3685 | YLR131C | ACE2 SGDID:S000004121, Chr XII from 406823-404511, reverse complement, Verified ORF, "Transcription factor that activates expression of early G1-specific genes, localizes to daughter cell nuclei after cytokinesis and delays G1 progression in daughters, localization is regulated by phosphorylation; potential Cdc28p substrate" |
| 3686 | YLR132C | YLR132C SGDID:S000004122, Chr XII from 408156-407284, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-tagged protein localizes to mitochondria and nucleus; YLR132C is an essential gene" |
| 3687 | YLR133W | CKI1 SGDID:S000004123, Chr XII from 408446-410194, Verified ORF, "Choline kinase, catalyzing the first step in phosphatidylcholine synthesis via the CDP-choline (Kennedy pathway); exhibits some ethanolamine kinase activity contributing to phosphatidylethanolamine synthesis via the CDP-ethanolamine pathway" |
| 3688 | YLR134W | PDC5 SGDID:S000004124, Chr XII from 410724-412415, Verified ORF, "Minor isoform of pyruvate decarboxylase, key enzyme in alcoholic fermentation, decarboxylates pyruvate to acetaldehyde, regulation is glucose- and ethanol-dependent, repressed by thiamine, involved in amino acid catabolism" |
| 3689 | YLR135W | SLX4 SGDID:S000004125, Chr XII from 413282-415528, Verified ORF, "Subunit of a complex, with Slx1p, that hydrolyzes 5' branches from duplex DNA in response to stalled or converging replication forks; function overlaps with that of Sgs1p-Top3p" |
| 3690 | YLR136C | TIS11 SGDID:S000004126, Chr XII from 416659-415802, reverse complement, Verified ORF, "mRNA-binding protein expressed during iron starvation; binds to a sequence element in the 3'-untranslated regions of specific mRNAs to mediate their degradation; involved in iron homeostasis" |
| 3691 | YLR137W | YLR137W SGDID:S000004127, Chr XII from 417007-418110, Uncharacterized ORF, "Putative protein of unknown function" |
| 3692 | YLR138W | NHA1 SGDID:S000004128, Chr XII from 418438-421395, Verified ORF, "Na+/H+ antiporter involved in sodium and potassium efflux through the plasma membrane; required for alkali cation tolerance at acidic pH" |
| 3693 | YLR139C | SLS1 SGDID:S000004129, Chr XII from 423474-421543, reverse complement, Verified ORF, "Mitochondrial membrane protein that coordinates expression of mitochondrially-encoded genes; may facilitate delivery of mRNA to membrane-bound translation machinery" |
| 3694 | YLR141W | RRN5 SGDID:S000004131, Chr XII from 423684-424775, Verified ORF, "Protein involved in transcription of rDNA by RNA polymerase I; transcription factor, member of UAF (upstream activation factor) family along with Rrn9p and Rrn10p" |
| 3695 | YLR142W | PUT1 SGDID:S000004132, Chr XII from 425187-426617, Verified ORF, "Proline oxidase, nuclear-encoded mitochondrial protein involved in utilization of proline as sole nitrogen source; PUT1 transcription is induced by Put3p in the presence of proline and the absence of a preferred nitrogen source" |
| 3696 | YLR143W | YLR143W SGDID:S000004133, Chr XII from 427330-429387, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-tagged protein localizes to the cytoplasm; YLR143W is not an essential gene" |
| 3697 | YLR144C | ACF2 SGDID:S000004134, Chr XII from 432017-429678, reverse complement, Verified ORF, "Intracellular beta-1,3-endoglucanase, expression is induced during sporulation; may have a role in cortical actin cytoskeleton assembly" |
| 3698 | YLR145W | RMP1 SGDID:S000004135, Chr XII from 432169-432774, Verified ORF, "Subunit of RNase MRP, which processes pre-rRNA and has a role in cell cycle-regulated degradation of daughter cell-specific mRNAs; unlike most subunits, not shared between RNase MRP and nuclear RNase P" |
| 3699 | YLR146C | SPE4 SGDID:S000004136, Chr XII from 433726-432824, reverse complement, Verified ORF, "Spermine synthase, required for the biosynthesis of spermine and also involved in biosynthesis of pantothenic acid" |
| 3700 | YLR146W-A | YLR146W-A SGDID:S000113566, Chr XII from 433871-434059, Uncharacterized ORF, "Putative protein of unknown function" |
| 3701 | YLR147C | SMD3 SGDID:S000004137, Chr XII from 434464-434159, reverse complement, Verified ORF, "Core Sm protein Sm D3; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D3" |
| 3702 | YLR148W | PEP3 SGDID:S000004138, Chr XII from 434642-437398, Verified ORF, "Component of CORVET tethering complex; vacuolar peripheral membrane protein that promotes vesicular docking/fusion reactions in conjunction with SNARE proteins, required for vacuolar biogenesis" |
| 3703 | YLR149C | YLR149C SGDID:S000004139, Chr XII from 439824-437632, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YLR149C is not an essential gene" |
| 3704 | YLR150W | STM1 SGDID:S000004140, Chr XII from 440468-441289, Verified ORF, "Protein that binds G4 quadruplex and purine motif triplex nucleic acid; acts with Cdc13p to maintain telomere structure; interacts with ribosomes and subtelomeric Y' DNA; multicopy suppressor of tom1 and pop2 mutations" |
| 3705 | YLR151C | PCD1 SGDID:S000004141, Chr XII from 442738-441716, reverse complement, Verified ORF, "Peroxisomal nudix pyrophosphatase with specificity for coenzyme A and CoA derivatives, may function to remove potentially toxic oxidized CoA disulfide from peroxisomes to maintain the capacity for beta-oxidation of fatty acids" |
| 3706 | YLR152C | YLR152C SGDID:S000004142, Chr XII from 444689-442959, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YLR152C is not an essential gene" |
| 3707 | YLR153C | ACS2 SGDID:S000004143, Chr XII from 447576-445525, reverse complement, Verified ORF, "Acetyl-coA synthetase isoform which, along with Acs1p, is the nuclear source of acetyl-coA for histone acetylation; mutants affect global transcription; required for growth on glucose; expressed under anaerobic conditions" |
| 3708 | YLR154C | RNH203 SGDID:S000004144, Chr XII from 448315-447983, reverse complement, Verified ORF, "Ribonuclease H2 subunit, required for RNase H2 activity" |
| 3709 | YLR154C-G | YLR154C-G SGDID:S000028561, Chr XII from 462672-462523, reverse complement, Uncharacterized ORF, "Putative protein of unknown function identified by fungal homology comparisons and RT-PCR; this ORF is contained within RDN25-2 and RDN37-2" |
| 3710 | YLR154C-H | YLR154C-H SGDID:S000028562, Chr XII from 468959-468828, reverse complement, Uncharacterized ORF, "Putative protein of unknown function identified by fungal homology comparisons and RT-PCR; this ORF partially overlaps RND5-2" |
| 3711 | YLR154W-C | TAR1 SGDID:S000028422, Chr XII from 454697-455071, Verified ORF, "Mitochondrial protein of unknown function, overexpression suppresses an rpo41 mutation affecting mitochondrial RNA polymerase; encoded within the 25S rRNA gene on the opposite strand" |
| 3712 | YLR155C | ASP3-1 SGDID:S000004145, Chr XII from 470406-469318, reverse complement, Verified ORF, "Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C" |
| 3713 | YLR156C-A | YLR156C-A SGDID:S000028564, Chr XII from 472611-472480, reverse complement, Uncharacterized ORF, "Putative protein of unknown function identified by fungal homology comparisons and RT-PCR; this ORF partially overlaps RND5-3" |
| 3714 | YLR156W | YLR156W SGDID:S000004146, Chr XII from 472114-472458, Uncharacterized ORF, "Putative protein of unknown function; exhibits a two-hybrid interaction with Jsn1p in a large-scale analysis" |
| 3715 | YLR157C | ASP3-2 SGDID:S000004147, Chr XII from 474058-472970, reverse complement, Verified ORF, "Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C" |
| 3716 | YLR157C-A | YLR157C-A SGDID:S000007373, Chr XII from 481602-480280, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 3717 | YLR157C-B | YLR157C-B SGDID:S000007374, Chr XII from 481602-480298,480296-476334, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 3718 | YLR157C-C | YLR157C-C SGDID:S000028565, Chr XII from 482191-482060, reverse complement, Uncharacterized ORF, "Putative protein of unknown function identified by fungal homology comparisons and RT-PCR; this ORF partially overlaps RND5-4" |
| 3719 | YLR157W-D | YLR157W-D SGDID:S000028677, Chr XII from 475765-475977, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 3720 | YLR157W-E | YLR157W-E SGDID:S000028678, Chr XII from 481874-482038, Uncharacterized ORF, "Putative protein of unknown function identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching; partially overlaps a Ty1 element" |
| 3721 | YLR158C | ASP3-3 SGDID:S000004148, Chr XII from 483638-482550, reverse complement, Verified ORF, "Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C" |
| 3722 | YLR159C-A | YLR159C-A SGDID:S000028566, Chr XII from 485843-485712, reverse complement, Uncharacterized ORF, "Putative protein of unknown function identified by fungal homology comparisons and RT-PCR; this ORF partially overlaps RND5-5" |
| 3723 | YLR159W | YLR159W SGDID:S000004149, Chr XII from 485346-485690, Uncharacterized ORF, "Putative protein of unknown function; YLR156W, YLR159W, and YLR161W are three identical open reading frames encoded near the ribosomal DNA region of chromosome 12" |
| 3724 | YLR160C | ASP3-4 SGDID:S000004150, Chr XII from 487290-486202, reverse complement, Verified ORF, "Cell-wall L-asparaginase II, involved in asparagine catabolism; expression is induced during nitrogen starvation; four copies of ASP3 are present in the genome reference strain S288C" |
| 3725 | YLR161W | YLR161W SGDID:S000004151, Chr XII from 488998-489342, Uncharacterized ORF, "Putative protein of unknown function; YLR156W, YLR159W, and YLR161W are three identical open reading frames encoded near the ribosomal DNA region of chromosome 12" |
| 3726 | YLR162W | YLR162W SGDID:S000004152, Chr XII from 489574-489930, Uncharacterized ORF, "Putative protein of unknown function; overexpression confers resistance to the antimicrobial peptide MiAMP1" |
| 3727 | YLR162W-A | YLR162W-A SGDID:S000028567, Chr XII from 490407-490595, Uncharacterized ORF, "Putative protein of unknown function identified by fungal homology comparisons and RT-PCR" |
| 3728 | YLR163C | MAS1 SGDID:S000004153, Chr XII from 493256-491868, reverse complement, Verified ORF, "Smaller subunit of the mitochondrial processing protease (MPP), essential processing enzyme that cleaves the N-terminal targeting sequences from mitochondrially imported proteins" |
| 3729 | YLR164W | YLR164W SGDID:S000004154, Chr XII from 493885-494391, Verified ORF, "Mitochondrial inner membrane of unknown function; similar to Tim18p and Sdh4p; expression induced by nitrogen limitation in a GLN3, GAT1-dependent manner" |
| 3730 | YLR165C | PUS5 SGDID:S000004155, Chr XII from 495260-494496, reverse complement, Verified ORF, "Pseudouridine synthase, catalyzes only the formation of pseudouridine (Psi)-2819 in mitochondrial 21S rRNA; not essential for viability" |
| 3731 | YLR166C | SEC10 SGDID:S000004156, Chr XII from 498046-495431, reverse complement, Verified ORF, "Essential 100kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis" |
| 3732 | YLR167W | RPS31 SGDID:S000004157, Chr XII from 498949-499407, Verified ORF, "Fusion protein that is cleaved to yield a ribosomal protein of the small (40S) subunit and ubiquitin; ubiquitin may facilitate assembly of the ribosomal protein into ribosomes; interacts genetically with translation factor eIF2B" |
| 3733 | YLR168C | YLR168C SGDID:S000004158, Chr XII from 500272-499580, reverse complement, Uncharacterized ORF, "Putative protein of unknown function that may be involved in intramitochondrial sorting; similar to Ups1p and to human PRELI; GFP-tagged protein localizes to mitochondria; required for wild-type respiratory growth" |
| 3734 | YLR170C | APS1 SGDID:S000004160, Chr XII from 501051-500581, reverse complement, Verified ORF, "Small subunit of the clathrin-associated adaptor complex AP-1, which is involved in protein sorting at the trans-Golgi network; homolog of the sigma subunit of the mammalian clathrin AP-1 complex" |
| 3735 | YLR172C | DPH5 SGDID:S000004162, Chr XII from 502164-501262, reverse complement, Verified ORF, "Methyltransferase required for synthesis of diphthamide, which is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); not essential for viability; GFP-Dph5p fusion protein localizes to the cytoplasm" |
| 3736 | YLR173W | YLR173W SGDID:S000004163, Chr XII from 502423-504249, Uncharacterized ORF, "Putative protein of unknown function" |
| 3737 | YLR174W | IDP2 SGDID:S000004164, Chr XII from 504593-505831, Verified ORF, "Cytosolic NADP-specific isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate; levels are elevated during growth on non-fermentable carbon sources and reduced during growth on glucose" |
| 3738 | YLR175W | CBF5 SGDID:S000004165, Chr XII from 506136-507587, Verified ORF, "Pseudouridine synthase catalytic subunit of box H/ACA small nucleolar ribonucleoprotein particles (snoRNPs), acts on both large and small rRNAs and on snRNA U2" |
| 3739 | YLR176C | RFX1 SGDID:S000004166, Chr XII from 510234-507799, reverse complement, Verified ORF, "Major transcriptional repressor of DNA-damage-regulated genes, recruits repressors Tup1p and Cyc8p to their promoters; involved in DNA damage and replication checkpoint pathway; similar to a family of mammalian DNA binding RFX1-4 proteins" |
| 3740 | YLR177W | YLR177W SGDID:S000004167, Chr XII from 511056-512942, Uncharacterized ORF, "Putative protein of unknown function; phosphorylated by Dbf2p-Mob1p in vitro; some strains contain microsatellite polymophisms at this locus; YLR177W is not an essential gene" |
| 3741 | YLR178C | TFS1 SGDID:S000004168, Chr XII from 513823-513164, reverse complement, Verified ORF, "Carboxypeptidase Y inhibitor, function requires acetylation by the NatB N-terminal acetyltransferase; phosphatidylethanolamine-binding protein involved in protein kinase A signaling pathway" |
| 3742 | YLR179C | YLR179C SGDID:S000004169, Chr XII from 514715-514110, reverse complement, Uncharacterized ORF, "Protein of unknown function, transcription is activated by paralogous proteins Yrm1p and Yrr1p along with proteins involved in multidrug resistance; GFP-tagged protein localizes to the cytoplasm and nucleus; YLR179C is not essential" |
| 3743 | YLR180W | SAM1 SGDID:S000004170, Chr XII from 515264-516412, Verified ORF, "S-adenosylmethionine synthetase, catalyzes transfer of the adenosyl group of ATP to the sulfur atom of methionine; one of two differentially regulated isozymes (Sam1p and Sam2p)" |
| 3744 | YLR181C | VTA1 SGDID:S000004171, Chr XII from 517672-516680, reverse complement, Verified ORF, "Multivesicular body (MVB) protein involved in endosomal protein sorting; regulates Vps4p activity by promoting its oligomerization; has an N-terminal Vps60- and Did2- binding domain, a linker region, and a C-terminal Vps4p binding domain" |
| 3745 | YLR182W | SWI6 SGDID:S000004172, Chr XII from 517942-520353, Verified ORF, "Transcription cofactor, forms complexes with DNA-binding proteins Swi4p and Mbp1p to regulate transcription at the G1/S transition; involved in meiotic gene expression; localization regulated by phosphorylation; potential Cdc28p substrate" |
| 3746 | YLR183C | TOS4 SGDID:S000004173, Chr XII from 522014-520545, reverse complement, Verified ORF, "Transcription factor that binds to a number of promoter regions, particularly promoters of some genes involved in pheromone response and cell cycle; potential Cdc28p substrate; expression is induced in G1 by bound SBF" |
| 3747 | YLR185W | RPL37A SGDID:S000004175, Chr XII from 522665-522671,523031-523290, Verified ORF, "Protein component of the large (60S) ribosomal subunit, has similarity to Rpl37Bp and to rat L37 ribosomal protein" |
| 3748 | YLR186W | EMG1 SGDID:S000004176, Chr XII from 523634-524392, Verified ORF, "Member of the alpha/beta knot fold methyltransferase superfamily; required for maturation of 18S rRNA and for 40S ribosome production; interacts with RNA and with S-adenosylmethionine; associates with spindle/microtubules; forms homodimers" |
| 3749 | YLR187W | SKG3 SGDID:S000004177, Chr XII from 524867-527947, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; potential Cdc28p substrate; similar to Caf120p and Skg4p" |
| 3750 | YLR188W | MDL1 SGDID:S000004178, Chr XII from 528302-530389, Verified ORF, "Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter, mediates export of peptides generated upon proteolysis of mitochondrial proteins, plays a role in the regulation of cellular resistance to oxidative stress" |
| 3751 | YLR189C | ATG26 SGDID:S000004179, Chr XII from 534395-530799, reverse complement, Verified ORF, "UDP-glucose:sterol glucosyltransferase, conserved enzyme involved in synthesis of sterol glucoside membrane lipids; in contrast to ATG26 from P. pastoris, S. cerevisiae ATG26 is not involved in autophagy" |
| 3752 | YLR190W | MMR1 SGDID:S000004180, Chr XII from 535216-536691, Verified ORF, "Phosphorylated protein of the mitochondrial outer membrane, localizes only to mitochondria of the bud; interacts with Myo2p to mediate mitochondrial distribution to buds; mRNA is targeted to the bud via the transport system involving She2p" |
| 3753 | YLR191W | PEX13 SGDID:S000004181, Chr XII from 537274-538434, Verified ORF, "Integral peroxisomal membrane required for the translocation of peroxisomal matrix proteins, interacts with the PTS1 signal recognition factor Pex5p and the PTS2 signal recognition factor Pex7p, forms a complex with Pex14p and Pex17p" |
| 3754 | YLR192C | HCR1 SGDID:S000004182, Chr XII from 539591-538794, reverse complement, Verified ORF, "Dual function protein involved in translation initiation as a substoichiometric component of eukaryotic translation initiation factor 3 (eIF3) and required for processing of 20S pre-rRNA; binds to eIF3 subunits Rpg1p and Prt1p and 18S rRNA" |
| 3755 | YLR193C | UPS1 SGDID:S000004183, Chr XII from 540538-540011, reverse complement, Verified ORF, "Mitochondrial intermembrane space protein that regulates alternative processing and sorting of Mgm1p and other proteins; required for normal mitochondrial morphology; ortholog of human PRELI" |
| 3756 | YLR194C | YLR194C SGDID:S000004184, Chr XII from 541575-540811, reverse complement, Uncharacterized ORF, "Structural constituent of the cell wall attached to the plasma membrane by a GPI-anchor; expression is upregulated in response to cell wall stress" |
| 3757 | YLR195C | NMT1 SGDID:S000004185, Chr XII from 543306-541939, reverse complement, Verified ORF, "N-myristoyl transferase, catalyzes the cotranslational, covalent attachment of myristic acid to the N-terminal glycine residue of several proteins involved in cellular growth and signal transduction" |
| 3758 | YLR196W | PWP1 SGDID:S000004186, Chr XII from 543970-545700, Verified ORF, "Protein with WD-40 repeats involved in rRNA processing; associates with trans-acting ribosome biogenesis factors; similar to beta-transducin superfamily" |
| 3759 | YLR197W | SIK1 SGDID:S000004187, Chr XII from 546099-547613, Verified ORF, "Essential evolutionarily-conserved nucleolar protein component of the box C/D snoRNP complexes that direct 2'-O-methylation of pre-rRNA during its maturation; overexpression causes spindle orientation defects" |
| 3760 | YLR199C | PBA1 SGDID:S000004189, Chr XII from 548771-548766,548679-547855, reverse complement, Verified ORF, "Protein involved in 20S proteasome assembly; forms a heterodimer with Add66p that binds to proteasome precursors; similar to human PAC1 constituent of the PAC1-PAC2 complex involved in proteasome assembly" |
| 3761 | YLR200W | YKE2 SGDID:S000004190, Chr XII from 549014-549358, Verified ORF, "Subunit of the heterohexameric Gim/prefoldin protein complex involved in the folding of alpha-tubulin, beta-tubulin, and actin" |
| 3762 | YLR201C | COQ9 SGDID:S000004191, Chr XII from 550295-549513, reverse complement, Verified ORF, "Protein required for ubiquinone (coenzyme Q) biosynthesis and respiratory growth; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes" |
| 3763 | YLR203C | MSS51 SGDID:S000004193, Chr XII from 551962-550652, reverse complement, Verified ORF, "Nuclear encoded protein required for translation of COX1 mRNA; binds to Cox1 protein" |
| 3764 | YLR204W | QRI5 SGDID:S000004194, Chr XII from 552272-552607, Verified ORF, "Mitochondrial inner membrane protein, required for accumulation of spliced COX1 mRNA; may have an additional role in translation of COX1 mRNA" |
| 3765 | YLR205C | HMX1 SGDID:S000004195, Chr XII from 553679-552726, reverse complement, Verified ORF, "ER localized, heme-binding peroxidase involved in the degradation of heme; does not exhibit heme oxygenase activity despite similarity to heme oxygenases; expression regulated by AFT1" |
| 3766 | YLR206W | ENT2 SGDID:S000004196, Chr XII from 554580-556421, Verified ORF, "Epsin-like protein required for endocytosis and actin patch assembly and functionally redundant with Ent1p; contains clathrin-binding motif at C-terminus" |
| 3767 | YLR207W | HRD3 SGDID:S000004197, Chr XII from 556790-559291, Verified ORF, "Resident protein of the ER membrane that plays a central role in ER-associated protein degradation (ERAD), forms HRD complex with Hrd1p and ERAD determinants that engages in lumen to cytosol communication and coordination of ERAD events" |
| 3768 | YLR208W | SEC13 SGDID:S000004198, Chr XII from 559553-560446, Verified ORF, "Component of both the Nup84 nuclear pore sub-complex and of the COPII complex (Sar1p, Sec13p, Sec16p, Sec23p, Sec24p, Sec31p, Sfb2p, and Sfb3p) which is important for the formation of ER to Golgi transport vesicles" |
| 3769 | YLR209C | PNP1 SGDID:S000004199, Chr XII from 561734-560799, reverse complement, Verified ORF, "Purine nucleoside phosphorylase, specifically metabolizes inosine and guanosine nucleosides; involved in the nicotinamide riboside salvage pathway" |
| 3770 | YLR210W | CLB4 SGDID:S000004200, Chr XII from 562010-563392, Verified ORF, "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the G2/M transition; may be involved in DNA replication and spindle assembly; accumulates during S phase and G2, then targeted for ubiquitin-mediated degradation" |
| 3771 | YLR211C | YLR211C SGDID:S000004201, Chr XII from 564533-564516,564456-563794, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR211C is not an essential gene; ORF contains an intron" |
| 3772 | YLR212C | TUB4 SGDID:S000004202, Chr XII from 566283-564862, reverse complement, Verified ORF, "Gamma-tubulin, involved in nucleating microtubules from both the cytoplasmic and nuclear faces of the spindle pole body" |
| 3773 | YLR213C | CRR1 SGDID:S000004203, Chr XII from 567924-566656, reverse complement, Verified ORF, "Putative glycoside hydrolase of the spore wall envelope; required for normal spore wall assembly, possibly for cross-linking between the glucan and chitosan layers; expressed during sporulation" |
| 3774 | YLR214W | FRE1 SGDID:S000004204, Chr XII from 568569-570629, Verified ORF, "Ferric reductase and cupric reductase, reduces siderophore-bound iron and oxidized copper prior to uptake by transporters; expression induced by low copper and iron levels" |
| 3775 | YLR215C | CDC123 SGDID:S000004205, Chr XII from 571860-570778, reverse complement, Verified ORF, "Protein involved in nutritional control of the cell cycle; regulates abundance of the translation initiation factor eIF2; ortholog of human D123 protein" |
| 3776 | YLR216C | CPR6 SGDID:S000004206, Chr XII from 573213-572098, reverse complement, Verified ORF, "Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; binds to Hsp82p and contributes to chaperone activity" |
| 3777 | YLR218C | YLR218C SGDID:S000004208, Chr XII from 573920-573468, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR218C is not essential; mutants exhibit glycogen storage defects and growth defects on a non-fermentable carbon source" |
| 3778 | YLR219W | MSC3 SGDID:S000004209, Chr XII from 574153-576339, Verified ORF, "Protein of unknown function, green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; msc3 mutants are defective in directing meiotic recombination events to homologous chromatids; potential Cdc28p substrate" |
| 3779 | YLR220W | CCC1 SGDID:S000004210, Chr XII from 576827-577795, Verified ORF, "Putative vacuolar Fe2+/Mn2+ transporter; suppresses respiratory deficit of yfh1 mutants, which lack the ortholog of mammalian frataxin, by preventing mitochondrial iron accumulation" |
| 3780 | YLR221C | RSA3 SGDID:S000004211, Chr XII from 579026-578364, reverse complement, Verified ORF, "Protein with a likely role in ribosomal maturation, required for accumulation of wild-type levels of large (60S) ribosomal subunits; binds to the helicase Dbp6p in pre-60S ribosomal particles in the nucleolus" |
| 3781 | YLR222C | UTP13 SGDID:S000004212, Chr XII from 581773-579320, reverse complement, Verified ORF, "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" |
| 3782 | YLR223C | IFH1 SGDID:S000004213, Chr XII from 585492-582235, reverse complement, Verified ORF, "Essential protein with a highly acidic N-terminal domain; IFH1 exhibits genetic interactions with FHL1, overexpression interferes with silencing at telomeres and HM loci; potential Cdc28p substrate" |
| 3783 | YLR224W | YLR224W SGDID:S000004214, Chr XII from 586466-587575, Uncharacterized ORF, "F-box protein and component of SCF ubiquitin ligase complexes involved in ubiquitin-dependent protein catabolism; readily monoubiquitinated in vitro by SCF-Ubc4 complexes; YLR224W is not an essential gene" |
| 3784 | YLR225C | YLR225C SGDID:S000004215, Chr XII from 588920-587697, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR225C is not an essential gene" |
| 3785 | YLR226W | BUR2 SGDID:S000004216, Chr XII from 589356-590543, Verified ORF, "Cyclin for the Sgv1p (Bur1p) protein kinase; Sgv1p and Bur2p comprise a CDK-cyclin complex involved in transcriptional regulation through its phosphorylation of the carboxy-terminal domain of the largest subunit of RNA polymerase II" |
| 3786 | YLR227C | ADY4 SGDID:S000004217, Chr XII from 592045-590564, reverse complement, Verified ORF, "Structural component of the meiotic outer plaque, which is a membrane-organizing center that assembles on the cytoplasmic face of the spindle pole body during meiosis II and triggers the formation of the prospore membrane" |
| 3787 | YLR227W-A | YLR227W-A SGDID:S000007375, Chr XII from 593440-594762, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 3788 | YLR227W-B | YLR227W-B SGDID:S000007376, Chr XII from 593440-594744,594746-598708, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 3789 | YLR228C | ECM22 SGDID:S000004218, Chr XII from 602465-600021, reverse complement, Verified ORF, "Sterol regulatory element binding protein, regulates transcription of the sterol biosynthetic genes ERG2 and ERG3; member of the fungus-specific Zn[2]-Cys[6] binuclear cluster family of transcription factors; homologous to Upc2p" |
| 3790 | YLR229C | CDC42 SGDID:S000004219, Chr XII from 604789-604214, reverse complement, Verified ORF, "Small rho-like GTPase, essential for establishment and maintenance of cell polarity; mutants have defects in the organization of actin and septins" |
| 3791 | YLR231C | BNA5 SGDID:S000004221, Chr XII from 607121-605760, reverse complement, Verified ORF, "Kynureninase, required for the de novo biosynthesis of NAD from tryptophan via kynurenine; expression regulated by Hst1p" |
| 3792 | YLR233C | EST1 SGDID:S000004223, Chr XII from 609526-607427, reverse complement, Verified ORF, "TLC1 RNA-associated factor involved in telomere length regulation as the recruitment subunit of the telomerase holoenzyme, has a possible role in activating Est2p-TLC1-RNA bound to the telomere" |
| 3793 | YLR234W | TOP3 SGDID:S000004224, Chr XII from 609785-611755, Verified ORF, "DNA Topoisomerase III, conserved protein that functions in a complex with Sgs1p and Rmi1p to relax single-stranded negatively-supercoiled DNA preferentially, involved in telomere stability and regulation of mitotic recombination" |
| 3794 | YLR237W | THI7 SGDID:S000004227, Chr XII from 612369-614165, Verified ORF, "Plasma membrane transporter responsible for the uptake of thiamine, member of the major facilitator superfamily of transporters; mutation of human ortholog causes thiamine-responsive megaloblastic anemia" |
| 3795 | YLR238W | FAR10 SGDID:S000004228, Chr XII from 614757-616193, Verified ORF, "Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far7p, Far8p, Far9p, and Far11p; potential Cdc28p substrate" |
| 3796 | YLR239C | LIP2 SGDID:S000004229, Chr XII from 617320-616334, reverse complement, Verified ORF, "Lipoyl ligase, involved in the modification of mitochondrial enzymes by the attachment of lipoic acid groups" |
| 3797 | YLR240W | VPS34 SGDID:S000004230, Chr XII from 617535-620162, Verified ORF, "Phosphatidylinositol 3-kinase responsible for the synthesis of phosphatidylinositol 3-phosphate; forms membrane-associated signal transduction complex with Vps15p to regulate protein sorting; activated by the GTP-bound form of Gpa1p" |
| 3798 | YLR241W | YLR241W SGDID:S000004231, Chr XII from 620475-622823, Uncharacterized ORF, "Putative protein of unknown function, may be involved in detoxification" |
| 3799 | YLR242C | ARV1 SGDID:S000004232, Chr XII from 623885-622920, reverse complement, Verified ORF, "Protein required for normal intracellular sterol distribution and for sphingolipid metabolism; similar to Nup120p and C. elegans R05H5.5 protein" |
| 3800 | YLR243W | YLR243W SGDID:S000004233, Chr XII from 624205-625023, Uncharacterized ORF, "Putative protein of unknown function; YLR243W is an essential gene" |
| 3801 | YLR244C | MAP1 SGDID:S000004234, Chr XII from 626333-625170, reverse complement, Verified ORF, "Methionine aminopeptidase, catalyzes the cotranslational removal of N-terminal methionine from nascent polypeptides; function is partially redundant with that of Map2p" |
| 3802 | YLR245C | CDD1 SGDID:S000004235, Chr XII from 626932-626504, reverse complement, Verified ORF, "Cytidine deaminase; catalyzes the modification of cytidine to uridine in vitro but native RNA substrates have not been identified, localizes to both the nucleus and cytoplasm" |
| 3803 | YLR246W | ERF2 SGDID:S000004236, Chr XII from 627120-628199, Verified ORF, "Subunit of a palmitoyltransferase, composed of Erf2p and Shr5p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; mutants partially mislocalize Ras2p to the vacuole" |
| 3804 | YLR247C | IRC20 SGDID:S000004237, Chr XII from 633356-628686, reverse complement, Verified ORF, "Putative helicase; localizes to the mitochondrion and the nucleus; YLR247C is not an essential gene; null mutant displays increased levels of spontaneous Rad52p foci" |
| 3805 | YLR248W | RCK2 SGDID:S000004238, Chr XII from 634254-636086, Verified ORF, "Protein kinase involved in the response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations" |
| 3806 | YLR249W | YEF3 SGDID:S000004239, Chr XII from 636782-639916, Verified ORF, "Translational elongation factor 3, stimulates the binding of aminoacyl-tRNA (AA-tRNA) to ribosomes by releasing EF-1 alpha from the ribosomal complex; contains two ABC cassettes; binds and hydrolyses ATP" |
| 3807 | YLR250W | SSP120 SGDID:S000004240, Chr XII from 640319-641023, Verified ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 3808 | YLR251W | SYM1 SGDID:S000004241, Chr XII from 641466-642059, Verified ORF, "Protein required for ethanol metabolism; induced by heat shock and localized to the inner mitochondrial membrane; homologous to mammalian peroxisomal membrane protein Mpv17" |
| 3809 | YLR253W | YLR253W SGDID:S000004243, Chr XII from 642629-644338, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; transcription is periodic during the metabolic cycle; YLR253W is not an essential gene" |
| 3810 | YLR254C | NDL1 SGDID:S000004244, Chr XII from 644975-644406, reverse complement, Verified ORF, "Homolog of nuclear distribution factor NudE, NUDEL; interacts with Pac1p and regulates dynein targeting to microtubule plus ends" |
| 3811 | YLR256W | HAP1 SGDID:S000004246, Chr XII from 646417-650925, Verified ORF, "Zinc finger transcription factor involved in the complex regulation of gene expression in response to levels of heme and oxygen; the S288C sequence differs from other strain backgrounds due to a Ty1 insertion in the carboxy terminus" |
| 3812 | YLR256W-A | YLR256W-A SGDID:S000007377, Chr XII from 651119-652441, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 3813 | YLR257W | YLR257W SGDID:S000004247, Chr XII from 658828-659793, Uncharacterized ORF, "Putative protein of unknown function" |
| 3814 | YLR258W | GSY2 SGDID:S000004248, Chr XII from 660718-662835, Verified ORF, "Glycogen synthase, similar to Gsy1p; expression induced by glucose limitation, nitrogen starvation, heat shock, and stationary phase; activity regulated by cAMP-dependent, Snf1p and Pho85p kinases as well as by the Gac1p-Glc7p phosphatase" |
| 3815 | YLR259C | HSP60 SGDID:S000004249, Chr XII from 665004-663286, reverse complement, Verified ORF, "Tetradecameric mitochondrial chaperonin required for ATP-dependent folding of precursor polypeptides and complex assembly; prevents aggregation and mediates protein refolding after heat shock; role in mtDNA transmission; phosphorylated" |
| 3816 | YLR260W | LCB5 SGDID:S000004250, Chr XII from 665846-667909, Verified ORF, "Minor sphingoid long-chain base kinase, paralog of Lcb4p responsible for few percent of the total activity, possibly involved in synthesis of long-chain base phosphates, which function as signaling molecules" |
| 3817 | YLR262C | YPT6 SGDID:S000004252, Chr XII from 668893-668246, reverse complement, Verified ORF, "GTPase, Ras-like GTP binding protein involved in the secretory pathway, required for fusion of endosome-derived vesicles with the late Golgi, maturation of the vacuolar carboxypeptidase Y; has similarity to the human GTPase, Rab6" |
| 3818 | YLR262C-A | TMA7 SGDID:S000007246, Chr XII from 669664-669470, reverse complement, Verified ORF, "Protein of unknown that associates with ribosomes; null mutant exhibits translation defects, altered polyribosome profiles, and resistance to the translation inhibitor anisomcyin" |
| 3819 | YLR263W | RED1 SGDID:S000004253, Chr XII from 670342-672825, Verified ORF, "Protein component of the axial elements of the synaptonemal complex, involved in chromosome segregation during the first meiotic division; interacts with Hop1p; required for wild-type levels of Mek1p kinase activity" |
| 3820 | YLR264C-A | YLR264C-A SGDID:S000028808, Chr XII from 673946-673830, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 3821 | YLR264W | RPS28B SGDID:S000004254, Chr XII from 673133-673336, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps28Ap and has similarity to rat S28 ribosomal protein" |
| 3822 | YLR265C | NEJ1 SGDID:S000004255, Chr XII from 675457-674429, reverse complement, Verified ORF, "Protein involved in regulation of nonhomologous end joining; interacts with DNA ligase IV components Dnl4p and Lif1p; repressed by MAT heterozygosity; regulates cellular distribution of Lif1p" |
| 3823 | YLR266C | PDR8 SGDID:S000004256, Chr XII from 677726-675621, reverse complement, Verified ORF, "Transcription factor; targets include ATP-binding cassette (ABC) transporters, major facilitator superfamily transporters, and other genes involved in the pleiotropic drug resistance (PDR) phenomenon" |
| 3824 | YLR267W | BOP2 SGDID:S000004257, Chr XII from 678214-679926, Uncharacterized ORF, "Protein of unknown function, overproduction suppresses a pam1 slv3 double null mutation" |
| 3825 | YLR268W | SEC22 SGDID:S000004258, Chr XII from 680202-680846, Verified ORF, "R-SNARE protein; assembles into SNARE complex with Bet1p, Bos1p and Sed5p; cycles between the ER and Golgi complex; involved in anterograde and retrograde transport between the ER and Golgi; synaptobrevin homolog" |
| 3826 | YLR270W | DCS1 SGDID:S000004260, Chr XII from 681188-682240, Verified ORF, "Non-essential hydrolase involved in mRNA decapping, may function in a feedback mechanism to regulate deadenylation, contains pyrophosphatase activity and a HIT (histidine triad) motif; interacts with neutral trehalase Nth1p" |
| 3827 | YLR271W | YLR271W SGDID:S000004261, Chr XII from 682739-683563, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus and is induced in response to the DNA-damaging agent MMS" |
| 3828 | YLR272C | YCS4 SGDID:S000004262, Chr XII from 687204-683674, reverse complement, Verified ORF, "Non-SMC subunit of the condensin complex (Smc2p-Smc4p-Ycs4p-Brn1p-Ycg1p); required for establishment and maintenance of chromosome condensation, chromosome segregation, chromatin binding of condensin and silencing at the mating type locus" |
| 3829 | YLR273C | PIG1 SGDID:S000004263, Chr XII from 691031-689085, reverse complement, Verified ORF, "Putative targeting subunit for the type-1 protein phosphatase Glc7p that tethers it to the Gsy2p glycogen synthase" |
| 3830 | YLR274W | MCM5 SGDID:S000004264, Chr XII from 691557-693884, Verified ORF, "Component of the hexameric MCM complex, which is important for priming origins of DNA replication in G1 and becomes an active ATP-dependent helicase that promotes DNA melting and elongation when activated by Cdc7p-Dbf4p in S-phase" |
| 3831 | YLR275W | SMD2 SGDID:S000004265, Chr XII from 694380-694384,694475-694802, Verified ORF, "Core Sm protein Sm D2; part of heteroheptameric complex (with Smb1p, Smd1p, Smd3p, Sme1p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm D2" |
| 3832 | YLR276C | DBP9 SGDID:S000004266, Chr XII from 696832-695048, reverse complement, Verified ORF, "ATP-dependent RNA helicase of the DEAD-box family involved in biogenesis of the 60S ribosomal subunit" |
| 3833 | YLR277C | YSH1 SGDID:S000004267, Chr XII from 699497-697158, reverse complement, Verified ORF, "Putative endoribonuclease, subunit of the mRNA cleavage and polyadenylation specificity complex required for 3' processing of mRNAs" |
| 3834 | YLR278C | YLR278C SGDID:S000004268, Chr XII from 704026-700001, reverse complement, Uncharacterized ORF, "Zinc-cluster protein; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; mutant shows moderate growth defect on caffeine; YLR278C is not an essential gene" |
| 3835 | YLR281C | YLR281C SGDID:S000004271, Chr XII from 704962-704495, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YLR281C is not an essential gene" |
| 3836 | YLR283W | YLR283W SGDID:S000004273, Chr XII from 705188-706132, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YLR283W is not an essential gene" |
| 3837 | YLR284C | ECI1 SGDID:S000004274, Chr XII from 707042-706200, reverse complement, Verified ORF, "Peroxisomal delta3,delta2-enoyl-CoA isomerase, hexameric protein that converts 3-hexenoyl-CoA to trans-2-hexenoyl-CoA, essential for the beta-oxidation of unsaturated fatty acids, oleate-induced" |
| 3838 | YLR285C-A | YLR285C-A SGDID:S000028569, Chr XII from 708340-708170, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 3839 | YLR285W | NNT1 SGDID:S000004275, Chr XII from 707362-708147, Verified ORF, "Putative nicotinamide N-methyltransferase, has a role in rDNA silencing and in lifespan determination" |
| 3840 | YLR286C | CTS1 SGDID:S000004276, Chr XII from 710138-708450, reverse complement, Verified ORF, "Endochitinase, required for cell separation after mitosis; transcriptional activation during late G and early M cell cycle phases is mediated by transcription factor Ace2p" |
| 3841 | YLR287C | YLR287C SGDID:S000004277, Chr XII from 712060-710993, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR287C is not an essential gene" |
| 3842 | YLR287C-A | RPS30A SGDID:S000004278, Chr XII from 713160-713158,712727-712539, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps30Bp and has similarity to rat S30 ribosomal protein" |
| 3843 | YLR288C | MEC3 SGDID:S000004279, Chr XII from 714906-713482, reverse complement, Verified ORF, "DNA damage and meiotic pachytene checkpoint protein; subunit of a heterotrimeric complex (Rad17p-Mec3p-Ddc1p) that forms a sliding clamp, loaded onto partial duplex DNA by a clamp loader complex; homolog of human and S. pombe Hus1" |
| 3844 | YLR289W | GUF1 SGDID:S000004280, Chr XII from 715091-717028, Verified ORF, "Mitochondrial GTPase of unknown function, similar to E. coli elongation factor-type GTP-binding protein LepA and to LK1236.1 from Caenorhabditis elegans" |
| 3845 | YLR290C | YLR290C SGDID:S000004281, Chr XII from 717980-717147, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YLR290C is not an essential gene" |
| 3846 | YLR291C | GCD7 SGDID:S000004282, Chr XII from 719464-718319, reverse complement, Verified ORF, "Beta subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression" |
| 3847 | YLR292C | SEC72 SGDID:S000004283, Chr XII from 720372-719791, reverse complement, Verified ORF, "Non-essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER" |
| 3848 | YLR293C | GSP1 SGDID:S000004284, Chr XII from 721432-720773, reverse complement, Verified ORF, "GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; regulated by Prp20p, Rna1p, Yrb1p, Yrb2p, Yrp4p, Yrb30p, Cse1p and Kap95p; yeast Gsp2p homolog" |
| 3849 | YLR295C | ATP14 SGDID:S000004286, Chr XII from 722375-722001, reverse complement, Verified ORF, "Subunit h of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" |
| 3850 | YLR297W | YLR297W SGDID:S000004288, Chr XII from 724046-724435, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YLR297W is not an essential gene; induced by treatment with 8-methoxypsoralen and UVA irradiation" |
| 3851 | YLR298C | YHC1 SGDID:S000004289, Chr XII from 725418-724723, reverse complement, Verified ORF, "Component of the U1 snRNP complex required for pre-mRNA splicing; putative ortholog of human U1C protein, which is involved in formation of a complex between U1 snRNP and the pre-mRNA 5' splice site" |
| 3852 | YLR299W | ECM38 SGDID:S000004290, Chr XII from 726071-728053, Verified ORF, "Gamma-glutamyltranspeptidase, major glutathione-degrading enzyme; involved in detoxification of electrophilic xenobiotics; expression induced mainly by nitrogen starvation" |
| 3853 | YLR300W | EXG1 SGDID:S000004291, Chr XII from 728957-730303, Verified ORF, "Major exo-1,3-beta-glucanase of the cell wall, involved in cell wall beta-glucan assembly; exists as three differentially glycosylated isoenzymes" |
| 3854 | YLR301W | YLR301W SGDID:S000004292, Chr XII from 730827-731561, Uncharacterized ORF, "Protein of unknown function that interacts with Sec72p" |
| 3855 | YLR303W | MET17 SGDID:S000004294, Chr XII from 732544-733878, Verified ORF, "Methionine and cysteine synthase (O-acetyl homoserine-O-acetyl serine sulfhydrylase), required for sulfur amino acid synthesis" |
| 3856 | YLR304C | ACO1 SGDID:S000004295, Chr XII from 737550-735214, reverse complement, Verified ORF, "Aconitase, required for the tricarboxylic acid (TCA) cycle and also independently required for mitochondrial genome maintenance; phosphorylated; component of the mitochondrial nucleoid; mutation leads to glutamate auxotrophy" |
| 3857 | YLR305C | STT4 SGDID:S000004296, Chr XII from 743865-738163, reverse complement, Verified ORF, "Phosphatidylinositol-4-kinase that functions in the Pkc1p protein kinase pathway; required for normal vacuole morphology, cell wall integrity, and actin cytoskeleton organization" |
| 3858 | YLR306W | UBC12 SGDID:S000004297, Chr XII from 744153-744155,744290-744853, Verified ORF, "Enzyme that mediates the conjugation of Rub1p, a ubiquitin-like protein, to other proteins; related to E2 ubiquitin-conjugating enzymes" |
| 3859 | YLR307C-A | YLR307C-A SGDID:S000028525, Chr XII from 747113-746850, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 3860 | YLR307W | CDA1 SGDID:S000004298, Chr XII from 745622-746527, Verified ORF, "Chitin deacetylase, together with Cda2p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall" |
| 3861 | YLR308W | CDA2 SGDID:S000004299, Chr XII from 747939-748877, Verified ORF, "Chitin deacetylase, together with Cda1p involved in the biosynthesis ascospore wall component, chitosan; required for proper rigidity of the ascospore wall" |
| 3862 | YLR309C | IMH1 SGDID:S000004300, Chr XII from 751771-749036, reverse complement, Verified ORF, "Protein involved in vesicular transport, mediates transport between an endosomal compartment and the Golgi, contains a Golgi-localization (GRIP) domain that interacts with activated Arl1p-GTP to localize Imh1p to the Golgi" |
| 3863 | YLR310C | CDC25 SGDID:S000004301, Chr XII from 756995-752226, reverse complement, Verified ORF, "Membrane bound guanine nucleotide exchange factor (GEF or GDP-release factor); indirectly regulates adenylate cyclase through activation of Ras1p and Ras2p by stimulating the exchange of GDP for GTP; required for progression through G1" |
| 3864 | YLR312C | YLR312C SGDID:S000004303, Chr XII from 758835-757639, reverse complement, Uncharacterized ORF, "Protein of unknown function; null mutant quiescent and non-quiescent cells exhibit reduced reproductive capacity" |
| 3865 | YLR312W-A | MRPL15 SGDID:S000004304, Chr XII from 759482-760243, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 3866 | YLR313C | SPH1 SGDID:S000004305, Chr XII from 762342-760357, reverse complement, Verified ORF, "Protein involved in shmoo formation and bipolar bud site selection; homologous to Spa2p, localizes to sites of polarized growth in a cell cycle dependent- and Spa2p-dependent manner, interacts with MAPKKs Mkk1p, Mkk2p, and Ste7p" |
| 3867 | YLR314C | CDC3 SGDID:S000004306, Chr XII from 764137-762575, reverse complement, Verified ORF, "Component of the septin ring of the mother-bud neck that is required for cytokinesis; septins recruit proteins to the neck and can act as a barrier to diffusion at the membrane, and they comprise the 10nm filaments seen with EM" |
| 3868 | YLR315W | NKP2 SGDID:S000004307, Chr XII from 764808-765269, Verified ORF, "Non-essential kinetochore protein, subunit of the Ctf19 central kinetochore complex (Ctf19p-Mcm21p-Okp1p-Mcm22p-Mcm16p-Ctf3p-Chl4p-Mcm19p-Nkp1p-Nkp2p-Ame1p-Mtw1p)" |
| 3869 | YLR316C | TAD3 SGDID:S000004308, Chr XII from 766358-766250,766181-766130,766073-765266, reverse complement, Verified ORF, "Subunit of tRNA-specific adenosine-34 deaminase, forms a heterodimer with Tad2p that converts adenosine to inosine at the wobble position of several tRNAs" |
| 3870 | YLR318W | EST2 SGDID:S000004310, Chr XII from 766542-769196, Verified ORF, "Reverse transcriptase subunit of the telomerase holoenzyme, essential for telomerase core catalytic activity, involved in other aspects of telomerase assembly and function; mutations in human homolog are associated with aplastic anemia" |
| 3871 | YLR319C | BUD6 SGDID:S000004311, Chr XII from 771684-769318, reverse complement, Verified ORF, "Actin- and formin-interacting protein, involved in actin cable nucleation and polarized cell growth; isolated as bipolar budding mutant; potential Cdc28p substrate" |
| 3872 | YLR320W | MMS22 SGDID:S000004312, Chr XII from 771940-776304, Verified ORF, "Protein that acts with Mms1p in a repair pathway that may be involved in resolving replication intermediates or preventing the damage caused by blocked replication forks; required for accurate meiotic chromosome segregation" |
| 3873 | YLR321C | SFH1 SGDID:S000004313, Chr XII from 777864-776584, reverse complement, Verified ORF, "Component of the RSC chromatin remodeling complex; essential gene required for cell cycle progression and maintenance of proper ploidy; phosphorylated in the G1 phase of the cell cycle; Snf5p paralog" |
| 3874 | YLR323C | CWC24 SGDID:S000004315, Chr XII from 778952-778173, reverse complement, Verified ORF, "Essential protein, component of a complex containing Cef1p; has similarity to S. pombe Cwf24p" |
| 3875 | YLR324W | PEX30 SGDID:S000004316, Chr XII from 779215-780786, Verified ORF, "Peroxisomal integral membrane protein, involved in negative regulation of peroxisome number; partially functionally redundant with Pex31p; genetic interactions suggest action at a step downstream of steps mediated by Pex28p and Pex29p" |
| 3876 | YLR325C | RPL38 SGDID:S000004317, Chr XII from 781379-781143, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, has similarity to rat L38 ribosomal protein" |
| 3877 | YLR326W | YLR326W SGDID:S000004318, Chr XII from 782174-782896, Uncharacterized ORF, "Hypothetical protein" |
| 3878 | YLR327C | TMA10 SGDID:S000004319, Chr XII from 783387-783127, reverse complement, Verified ORF, "Protein of unknown function that associates with ribosomes" |
| 3879 | YLR328W | NMA1 SGDID:S000004320, Chr XII from 784913-786118, Verified ORF, "Nicotinic acid mononucleotide adenylyltransferase, involved in pathways of NAD biosynthesis, including the de novo, NAD(+) salvage, and nicotinamide riboside salvage pathways" |
| 3880 | YLR329W | REC102 SGDID:S000004321, Chr XII from 786442-786615,786713-787333, Verified ORF, "Protein involved in early stages of meiotic recombination; required for chromosome synapsis; forms a complex with Rec104p and Spo11p necessary during the initiation of recombination" |
| 3881 | YLR330W | CHS5 SGDID:S000004322, Chr XII from 787664-789679, Verified ORF, "Component of the exomer complex, which also contains Csh6p, Bch1p, Bch2p, and Bud7p and is involved in export of selected proteins, such as chitin synthase Chs3p, from the Golgi to the plasma membrane" |
| 3882 | YLR332W | MID2 SGDID:S000004324, Chr XII from 790676-791806, Verified ORF, "O-glycosylated plasma membrane protein that acts as a sensor for cell wall integrity signaling and activates the pathway; interacts with Rom2p, a guanine nucleotide exchange factor for Rho1p, and with cell integrity pathway protein Zeo1p" |
| 3883 | YLR333C | RPS25B SGDID:S000004325, Chr XII from 795899-795573, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps25Ap and has similarity to rat S25 ribosomal protein" |
| 3884 | YLR335W | NUP2 SGDID:S000004327, Chr XII from 797430-799592, Verified ORF, "Nucleoporin involved in nucleocytoplasmic transport, binds to either the nucleoplasmic or cytoplasmic faces of the nuclear pore complex depending on Ran-GTP levels; also has a role in chromatin organization" |
| 3885 | YLR336C | SGD1 SGDID:S000004328, Chr XII from 802396-799697, reverse complement, Verified ORF, "Essential nuclear protein with a possible role in the osmoregulatory glycerol response; interacts with phospholipase C (Plc1p); putative homolog of human NOM1 which is implicated in acute myeloid leukemia" |
| 3886 | YLR337C | VRP1 SGDID:S000004329, Chr XII from 805106-802653, reverse complement, Verified ORF, "Proline-rich actin-associated protein involved in cytoskeletal organization and cytokinesis; related to mammalian Wiskott-Aldrich syndrome protein (WASP)-interacting protein (WIP)" |
| 3887 | YLR340W | RPP0 SGDID:S000004332, Chr XII from 805887-806825, Verified ORF, "Conserved ribosomal protein P0 similar to rat P0, human P0, and E. coli L10e; shown to be phosphorylated on serine 302" |
| 3888 | YLR341W | SPO77 SGDID:S000004333, Chr XII from 807385-808818, Verified ORF, "Meiosis-specific protein of unknown function, required for spore wall formation during sporulation; dispensable for both nuclear divisions during meiosis" |
| 3889 | YLR342W | FKS1 SGDID:S000004334, Chr XII from 809997-815627, Verified ORF, "Catalytic subunit of 1,3-beta-D-glucan synthase, functionally redundant with alternate catalytic subunit Gsc2p; binds to regulatory subunit Rho1p; involved in cell wall synthesis and maintenance; localizes to sites of cell wall remodeling" |
| 3890 | YLR342W-A | YLR342W-A SGDID:S000028571, Chr XII from 815810-815983, Uncharacterized ORF, "Putative protein of unknown function" |
| 3891 | YLR343W | GAS2 SGDID:S000004335, Chr XII from 816094-817761, Verified ORF, "1,3-beta-glucanosyltransferase, involved with Gas4p in spore wall assembly; has similarity to Gas1p" |
| 3892 | YLR344W | RPL26A SGDID:S000004336, Chr XII from 819312-819330,819778-820142, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl26Bp and has similarity to E. coli L24 and rat L26 ribosomal proteins; binds to 5.8S rRNA" |
| 3893 | YLR345W | YLR345W SGDID:S000004337, Chr XII from 820511-822040, Uncharacterized ORF, "Similar to 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase enzymes responsible for the metabolism of fructoso-2,6-bisphosphate; mRNA expression is repressed by the Rfx1p-Tup1p-Ssn6p repressor complex; YLR345W is not an essential gene" |
| 3894 | YLR346C | YLR346C SGDID:S000004338, Chr XII from 822592-822287, reverse complement, Uncharacterized ORF, "Putative protein of unknown function found in mitochondria; expression is regulated by transcription factors involved in pleiotropic drug resistance, Pdr1p and Yrr1p; YLR346C is not an essential gene" |
| 3895 | YLR347C | KAP95 SGDID:S000004339, Chr XII from 826412-823827, reverse complement, Verified ORF, "Karyopherin beta, forms a dimeric complex with Srp1p (Kap60p) that mediates nuclear import of cargo proteins via a nuclear localization signal (NLS), interacts with nucleoporins to guide transport across the nuclear pore complex" |
| 3896 | YLR348C | DIC1 SGDID:S000004340, Chr XII from 827872-826976, reverse complement, Verified ORF, "Mitochondrial dicarboxylate carrier, integral membrane protein, catalyzes a dicarboxylate-phosphate exchange across the inner mitochondrial membrane, transports cytoplasmic dicarboxylates into the mitochondrial matrix" |
| 3897 | YLR350W | ORM2 SGDID:S000004342, Chr XII from 828729-829379, Verified ORF, "Evolutionarily conserved protein with similarity to Orm1p, required for resistance to agents that induce the unfolded protein response; human ortholog is located in the endoplasmic reticulum" |
| 3898 | YLR351C | NIT3 SGDID:S000004343, Chr XII from 830363-829488, reverse complement, Verified ORF, "Nit protein, one of two proteins in S. cerevisiae with similarity to the Nit domain of NitFhit from fly and worm and to the mouse and human Nit protein which interacts with the Fhit tumor suppressor; nitrilase superfamily member" |
| 3899 | YLR352W | YLR352W SGDID:S000004344, Chr XII from 831115-833538, Uncharacterized ORF, "Putative protein of unknown function with similarity to F-box proteins; interacts with Skp1p and Cdc53p; YLR352W is not an essential gene" |
| 3900 | YLR353W | BUD8 SGDID:S000004345, Chr XII from 834351-836162, Verified ORF, "Protein involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern, and bud at the proximal pole" |
| 3901 | YLR354C | TAL1 SGDID:S000004346, Chr XII from 837356-836349, reverse complement, Verified ORF, "Transaldolase, enzyme in the non-oxidative pentose phosphate pathway; converts sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate to erythrose 4-phosphate and fructose 6-phosphate" |
| 3902 | YLR355C | ILV5 SGDID:S000004347, Chr XII from 839252-838065, reverse complement, Verified ORF, "Acetohydroxyacid reductoisomerase, mitochondrial protein involved in branched-chain amino acid biosynthesis, also required for maintenance of wild-type mitochondrial DNA and found in mitochondrial nucleoids" |
| 3903 | YLR356W | YLR356W SGDID:S000004348, Chr XII from 840320-840913, Uncharacterized ORF, "Putative protein of unknown function with similarity to SCM4; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YLR356W is not an essential gene" |
| 3904 | YLR357W | RSC2 SGDID:S000004349, Chr XII from 841330-843999, Verified ORF, "Component of the RSC chromatin remodeling complex; required for expression of mid-late sporulation-specific genes; involved in telomere maintenance" |
| 3905 | YLR359W | ADE13 SGDID:S000004351, Chr XII from 844281-845729, Verified ORF, "Adenylosuccinate lyase, catalyzes two steps in the 'de novo' purine nucleotide biosynthetic pathway; expression is repressed by adenine and activated by Bas1p and Pho2p; mutations in human ortholog ADSL cause adenylosuccinase deficiency" |
| 3906 | YLR360W | VPS38 SGDID:S000004352, Chr XII from 846102-847421, Verified ORF, "Part of a Vps34p phosphatidylinositol 3-kinase complex that functions in carboxypeptidase Y (CPY) sorting; binds Vps30p and Vps34p to promote production of phosphatidylinositol 3-phosphate (PtdIns3P) which stimulates kinase activity" |
| 3907 | YLR361C | DCR2 SGDID:S000004353, Chr XII from 849123-847387, reverse complement, Verified ORF, "Phosphoesterase involved in downregulation of the unfolded protein response, at least in part via dephosphorylation of Ire1p; dosage-dependent positive regulator of the G1/S phase transition through control of the timing of START" |
| 3908 | YLR361C-A | YLR361C-A SGDID:S000028845, Chr XII from 849678-849382, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 3909 | YLR362W | STE11 SGDID:S000004354, Chr XII from 849865-852018, Verified ORF, "Signal transducing MEK kinase involved in pheromone response and pseudohyphal/invasive growth pathways where it phosphorylates Ste7p, and the high osmolarity response pathway, via phosphorylation of Pbs2p; regulated by Ste20p and Ste50p" |
| 3910 | YLR363C | NMD4 SGDID:S000004355, Chr XII from 853150-852494, reverse complement, Verified ORF, "Protein interacting with Nam7p, may be involved in the nonsense-mediated mRNA decay pathway" |
| 3911 | YLR363W-A | YLR363W-A SGDID:S000007620, Chr XII from 853460-853717, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus" |
| 3912 | YLR364W | GRX8 SGDID:S000004356, Chr XII from 854061-854390, Uncharacterized ORF, "Putative cytosolic dithiol glutaredoxin; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; non-essential gene that is strongly induced by arsenic" |
| 3913 | YLR367W | RPS22B SGDID:S000004359, Chr XII from 856441-856573,857057-857316, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps22Ap and has similarity to E. coli S8 and rat S15a ribosomal proteins" |
| 3914 | YLR368W | MDM30 SGDID:S000004360, Chr XII from 857539-859335, Verified ORF, "F-box protein; physically associates with mitochondria and is required for normal mitochondrial fusion in rich medium, during sporulation, and in mating cells; promotes ubiquitin-mediated degradation of Gal4p in some strains" |
| 3915 | YLR369W | SSQ1 SGDID:S000004361, Chr XII from 859551-861524, Verified ORF, "Mitochondrial hsp70-type molecular chaperone, required for assembly of iron/sulfur clusters into proteins at a step after cluster synthesis, and for maturation of Yfh1p, which is a homolog of human frataxin implicated in Friedreich's ataxia" |
| 3916 | YLR370C | ARC18 SGDID:S000004362, Chr XII from 862253-861717, reverse complement, Verified ORF, "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches" |
| 3917 | YLR371W | ROM2 SGDID:S000004363, Chr XII from 862713-866783, Verified ORF, "GDP/GTP exchange protein (GEP) for Rho1p and Rho2p; mutations are synthetically lethal with mutations in rom1, which also encodes a GEP" |
| 3918 | YLR372W | SUR4 SGDID:S000004364, Chr XII from 867353-868390, Verified ORF, "Elongase, involved in fatty acid and sphingolipid biosynthesis; synthesizes very long chain 20-26-carbon fatty acids from C18-CoA primers; involved in regulation of sphingolipid biosynthesis" |
| 3919 | YLR373C | VID22 SGDID:S000004365, Chr XII from 871366-868661, reverse complement, Verified ORF, "Glycosylated integral membrane protein localized to the plasma membrane; plays a role in fructose-1,6-bisphosphatase (FBPase) degradation; involved in FBPase transport from the cytosol to Vid (vacuole import and degradation) vesicles" |
| 3920 | YLR375W | STP3 SGDID:S000004367, Chr XII from 871696-872727, Verified ORF, "Zinc-finger protein of unknown function, possibly involved in pre-tRNA splicing and in uptake of branched-chain amino acids" |
| 3921 | YLR376C | PSY3 SGDID:S000004368, Chr XII from 873553-872825, reverse complement, Verified ORF, "Protein of unknown function; deletion results in a mutator phenotype suggesting a role for this protein as a mutational suppressor; deletion increases sensitivity to anticancer drugs oxaliplatin and cisplatin but not mitomycin C" |
| 3922 | YLR377C | FBP1 SGDID:S000004369, Chr XII from 874791-873745, reverse complement, Verified ORF, "Fructose-1,6-bisphosphatase, key regulatory enzyme in the gluconeogenesis pathway, required for glucose metabolism" |
| 3923 | YLR378C | SEC61 SGDID:S000004370, Chr XII from 877177-875735, reverse complement, Verified ORF, "Essential subunit of Sec61 complex (Sec61p, Sbh1p, and Sss1p); forms a channel for SRP-dependent protein import and retrograde transport of misfolded proteins out of the ER; with Sec63 complex allows SRP-independent protein import into ER" |
| 3924 | YLR380W | CSR1 SGDID:S000004372, Chr XII from 878282-879508, Verified ORF, "Phosphatidylinositol transfer protein with a potential role in regulating lipid and fatty acid metabolism under heme-depleted conditions; interacts specifically with thioredoxin peroxidase; may have a role in oxidative stress resistance" |
| 3925 | YLR381W | CTF3 SGDID:S000004373, Chr XII from 879723-881924, Verified ORF, "Outer kinetochore protein that forms a complex with Mcm16p and Mcm22p; may bind the kinetochore to spindle microtubules" |
| 3926 | YLR382C | NAM2 SGDID:S000004374, Chr XII from 884751-882067, reverse complement, Verified ORF, "Mitochondrial leucyl-tRNA synthetase, also has a direct role in splicing of several mitochondrial group I introns; indirectly required for mitochondrial genome maintenance" |
| 3927 | YLR383W | SMC6 SGDID:S000004375, Chr XII from 885288-888632, Verified ORF, "Protein involved in structural maintenance of chromosomes; essential subunit of Mms21-Smc5-Smc6 complex; required for growth, DNA repair, interchromosomal and sister chromatid recombination; homologous to S. pombe rad18" |
| 3928 | YLR384C | IKI3 SGDID:S000004376, Chr XII from 892900-888851, reverse complement, Verified ORF, "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; maintains structural integrity of Elongator; homolog of human IKAP, mutations in which cause familial dysautonomia (FD)" |
| 3929 | YLR385C | SWC7 SGDID:S000004377, Chr XII from 893390-892992, reverse complement, Verified ORF, "Protein of unknown function, component of the Swr1p complex that incorporates Htz1p into chromatin" |
| 3930 | YLR386W | VAC14 SGDID:S000004378, Chr XII from 893628-896270, Verified ORF, "Protein involved in regulated synthesis of PtdIns(3,5)P(2), in control of trafficking of some proteins to the vacuole lumen via the MVB, and in maintenance of vacuole size and acidity; interacts with Fig4p; activator of Fab1p" |
| 3931 | YLR387C | REH1 SGDID:S000004379, Chr XII from 897672-896374, reverse complement, Verified ORF, "Protein of unknown function, similar to Rei1p but not involved in bud growth; contains dispersed C2H2 zinc finger domains" |
| 3932 | YLR388W | RPS29A SGDID:S000004380, Chr XII from 898651-898821, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps29Bp and has similarity to rat S29 and E. coli S14 ribosomal proteins" |
| 3933 | YLR389C | STE23 SGDID:S000004381, Chr XII from 902660-899577, reverse complement, Verified ORF, "Metalloprotease involved, with homolog Axl1p, in N-terminal processing of pro-a-factor to the mature form; member of the insulin-degrading enzyme family" |
| 3934 | YLR390W | ECM19 SGDID:S000004382, Chr XII from 903066-903404, Verified ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3935 | YLR390W-A | CCW14 SGDID:S000006429, Chr XII from 903724-904440, Verified ORF, "Covalently linked cell wall glycoprotein, present in the inner layer of the cell wall" |
| 3936 | YLR392C | YLR392C SGDID:S000004384, Chr XII from 906305-904749, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YLR392C is not an essential gene" |
| 3937 | YLR393W | ATP10 SGDID:S000004385, Chr XII from 907079-907918, Verified ORF, "Mitochondrial inner membrane protein required for assembly of the F0 sector of mitochondrial F1F0 ATP synthase, interacts genetically with ATP6" |
| 3938 | YLR394W | CST9 SGDID:S000004386, Chr XII from 907950-909398, Verified ORF, "SUMO E3 ligase; required for synaptonemal complex formation; localizes to synapsis initiation sites on meiotic chromosomes; potential Cdc28p substrate" |
| 3939 | YLR395C | COX8 SGDID:S000004387, Chr XII from 909965-909729, reverse complement, Verified ORF, "Subunit VIII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain" |
| 3940 | YLR396C | VPS33 SGDID:S000004388, Chr XII from 912310-910235, reverse complement, Verified ORF, "ATP-binding protein that is a subunit of the HOPS complex and the CORVET tethering complex; essential for membrane docking and fusion at both the Golgi-to-endosome and endosome-to-vacuole stages of protein transport" |
| 3941 | YLR397C | AFG2 SGDID:S000004389, Chr XII from 914892-912550, reverse complement, Verified ORF, "ATPase of the CDC48/PAS1/SEC18 (AAA) family, forms a hexameric complex; may be involved in degradation of aberrant mRNAs" |
| 3942 | YLR398C | SKI2 SGDID:S000004390, Chr XII from 919019-915156, reverse complement, Verified ORF, "Putative RNA helicase, involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs; forms complex with Ski3p and Ski8p; required for repressing propagation of dsRNA viruses" |
| 3943 | YLR399C | BDF1 SGDID:S000004391, Chr XII from 921596-919536, reverse complement, Verified ORF, "Protein involved in transcription initiation at TATA-containing promoters; associates with the basal transcription factor TFIID; contains two bromodomains; corresponds to the C-terminal region of mammalian TAF1; redundant with Bdf2p" |
| 3944 | YLR401C | DUS3 SGDID:S000004393, Chr XII from 924448-922442, reverse complement, Verified ORF, "Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus4p; contains a consensus oleate response element (ORE) in its promoter region" |
| 3945 | YLR403W | SFP1 SGDID:S000004395, Chr XII from 925567-927618, Verified ORF, "Transcription factor that controls expression of many ribosome biogenesis genes in response to nutrients and stress, regulates G2/M transitions during mitotic cell cycle and DNA-damage response, involved in cell size modulation" |
| 3946 | YLR404W | FLD1 SGDID:S000004396, Chr XII from 928742-929599, Verified ORF, "Seipin protein involved in lipid droplet morphology, number, and size; proposed to be involved in lipid metabolism; related to the human BSCL2 which is associated with lipodystrophy" |
| 3947 | YLR405W | DUS4 SGDID:S000004397, Chr XII from 929788-930891, Verified ORF, "Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus1p, and Dus3p" |
| 3948 | YLR406C | RPL31B SGDID:S000004398, Chr XII from 931754-931698,931348-931064, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl31Ap and has similarity to rat L31 ribosomal protein; associates with the karyopherin Sxm1p" |
| 3949 | YLR406C-A | YLR406C-A SGDID:S000028683, Chr XII from 932354-932205, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 3950 | YLR407W | YLR407W SGDID:S000004399, Chr XII from 932966-933655, Uncharacterized ORF, "Putative protein of unknown function; YLR407W is not an essential gene" |
| 3951 | YLR408C | YLR408C SGDID:S000004400, Chr XII from 934251-933883, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endosome; YLR408C is not an essential gene" |
| 3952 | YLR409C | UTP21 SGDID:S000004401, Chr XII from 937231-934412, reverse complement, Verified ORF, "Possible U3 snoRNP protein involved in maturation of pre-18S rRNA, based on computational analysis of large-scale protein-protein interaction data" |
| 3953 | YLR410W | VIP1 SGDID:S000004402, Chr XII from 937539-940979, Verified ORF, "Inositol hexakisphosphate (IP6) and inositol heptakisphosphate (IP7) kinase; generation of IP7 by Vip1p is important for phosphate signaling; likely involved in cortical actin cytoskeleton function, by analogy with S. pombe ortholog asp1" |
| 3954 | YLR410W-A | YLR410W-A SGDID:S000007379, Chr XII from 941481-942797, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 3955 | YLR410W-B | YLR410W-B SGDID:S000007380, Chr XII from 941481-942773,942775-946794, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 3956 | YLR411W | CTR3 SGDID:S000004403, Chr XII from 947251-947976, Verified ORF, "High-affinity copper transporter of the plasma membrane, acts as a trimer; gene is disrupted by a Ty2 transposon insertion in many laboratory strains of S. cerevisiae" |
| 3957 | YLR412C-A | YLR412C-A SGDID:S000028572, Chr XII from 950470-950264, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 3958 | YLR412W | BER1 SGDID:S000004404, Chr XII from 948366-949190, Verified ORF, "Protein involved in microtubule-related processes, N-acetylation; GFP-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YLR412W is not an essential gene; similar to Arabidopsis SRR1 gene" |
| 3959 | YLR413W | YLR413W SGDID:S000004405, Chr XII from 951153-953180, Uncharacterized ORF, "Putative protein of unknown function; YLR413W is not an essential gene" |
| 3960 | YLR414C | YLR414C SGDID:S000004406, Chr XII from 954141-953350, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the bud and cytoplasm; Hog1p is required for transcriptional induction in response to cell wall damage; YLR414C is not an essential gene" |
| 3961 | YLR415C | YLR415C SGDID:S000004407, Chr XII from 954594-954256, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YLR415C is not an essential gene" |
| 3962 | YLR417W | VPS36 SGDID:S000004409, Chr XII from 955007-956707, Verified ORF, "Component of the ESCRT-II complex; contains the GLUE (GRAM Like Ubiquitin binding in EAP45) domain which is involved in interactions with ESCRT-I and ubiquitin-dependent sorting of proteins into the endosome" |
| 3963 | YLR418C | CDC73 SGDID:S000004410, Chr XII from 958092-956911, reverse complement, Verified ORF, "Constituent of Paf1 complex with RNA polymerase II, Paf1p, Hpr1p, Ctr9, Leo1, Rtf1 and Ccr4p, distinct from Srb-containing Pol II complexes; required for expression of certain genes, modification of some histones, and telomere maintenance" |
| 3964 | YLR419W | YLR419W SGDID:S000004411, Chr XII from 958425-962732, Uncharacterized ORF, "Putative helicase with limited sequence similarity to human Rb protein; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YLR419W is not an essential gene" |
| 3965 | YLR420W | URA4 SGDID:S000004412, Chr XII from 963782-964876, Verified ORF, "Dihydroorotase, catalyzes the third enzymatic step in the de novo biosynthesis of pyrimidines, converting carbamoyl-L-aspartate into dihydroorotate" |
| 3966 | YLR421C | RPN13 SGDID:S000004413, Chr XII from 965557-965087, reverse complement, Verified ORF, "Subunit of the 19S regulatory particle of the 26S proteasome lid; acts as a ubiquitin receptor for the proteasome" |
| 3967 | YLR422W | YLR422W SGDID:S000004414, Chr XII from 965894-971692, Uncharacterized ORF, "Protein of unknown function with similarity to human DOCK proteins (guanine nucleotide exchange factors); interacts with Ino4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, YLR422W is not an essential protein" |
| 3968 | YLR423C | ATG17 SGDID:S000004415, Chr XII from 973167-971914, reverse complement, Verified ORF, "Scaffold protein responsible for pre-autophagosomal structure organization; regulatory subunit of an autophagy-specific complex that includes Atg1p and Atg13p; stimulates Atg1p kinase activity" |
| 3969 | YLR424W | SPP382 SGDID:S000004416, Chr XII from 973392-975518, Verified ORF, "Essential protein that forms a dimer with Ntr2p; also forms a trimer, with Ntr2p and Prp43p, that is involved in spliceosome disassembly; found also in a multisubunit complex with the splicing factor Clf1p; suppressor of prp38-1 mutation" |
| 3970 | YLR425W | TUS1 SGDID:S000004417, Chr XII from 982891-986814, Verified ORF, "Guanine nucleotide exchange factor (GEF) that functions to modulate Rho1p activity as part of the cell integrity signaling pathway; multicopy suppressor of tor2 mutation and ypk1 ypk2 double mutation; potential Cdc28p substrate" |
| 3971 | YLR426W | YLR426W SGDID:S000004418, Chr XII from 987059-987138,987210-988110, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; proposed to be involved in resistance to mechlorethamine and streptozotocin" |
| 3972 | YLR427W | MAG2 SGDID:S000004419, Chr XII from 988425-990437, Verified ORF, "Cytoplasmic protein of unknown function predicted to encode a DNA-3-methyladenine glycosidase II that catalyzes the hydrolysis of alkylated DNA" |
| 3973 | YLR429W | CRN1 SGDID:S000004421, Chr XII from 990774-992729, Verified ORF, "Coronin, cortical actin cytoskeletal component that associates with the Arp2p/Arp3p complex to regulate its activity; plays a role in regulation of actin patch assembly" |
| 3974 | YLR430W | SEN1 SGDID:S000004422, Chr XII from 993431-1000126, Verified ORF, "Presumed helicase required for RNA polymerase II transcription termination and processing of RNAs; homolog of Senataxin which causes Ataxia-Oculomotor Apraxia 2 and a dominant form of amyotrophic lateral sclerosis" |
| 3975 | YLR431C | ATG23 SGDID:S000004423, Chr XII from 1001700-1000339, reverse complement, Verified ORF, "Peripheral membrane protein required for the cytoplasm-to-vacuole targeting (Cvt) pathway; cycles between the pre-autophagosome (PAS) and non-PAS locations; forms a complex with Atg9p and Atg27p" |
| 3976 | YLR432W | IMD3 SGDID:S000004424, Chr XII from 1002554-1004125, Verified ORF, "Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed" |
| 3977 | YLR433C | CNA1 SGDID:S000004425, Chr XII from 1006005-1004344, reverse complement, Verified ORF, "Calcineurin A; one isoform (the other is CMP2) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1" |
| 3978 | YLR435W | TSR2 SGDID:S000004427, Chr XII from 1006375-1006992, Verified ORF, "Protein with a potential role in pre-rRNA processing" |
| 3979 | YLR436C | ECM30 SGDID:S000004428, Chr XII from 1011242-1007418, reverse complement, Verified ORF, "Non-essential protein of unknown function" |
| 3980 | YLR437C | YLR437C SGDID:S000004429, Chr XII from 1012020-1011619, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; epitope tagged protein localizes to the cytoplasm" |
| 3981 | YLR438C-A | LSM3 SGDID:S000006434, Chr XII from 1014175-1013906, reverse complement, Verified ORF, "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" |
| 3982 | YLR438W | CAR2 SGDID:S000004430, Chr XII from 1012498-1013772, Verified ORF, "L-ornithine transaminase (OTAse), catalyzes the second step of arginine degradation, expression is dually-regulated by allophanate induction and a specific arginine induction process; not nitrogen catabolite repression sensitive" |
| 3983 | YLR439W | MRPL4 SGDID:S000004431, Chr XII from 1014488-1015447, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 3984 | YLR440C | SEC39 SGDID:S000004432, Chr XII from 1017694-1015565, reverse complement, Verified ORF, "Protein of unknown function proposed to be involved in protein secretion; interacts with Dsl1p and localizes to the ER and nuclear envelope" |
| 3985 | YLR441C | RPS1A SGDID:S000004433, Chr XII from 1018905-1018138, reverse complement, Verified ORF, "Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Bp and has similarity to rat S3a ribosomal protein" |
| 3986 | YLR442C | SIR3 SGDID:S000004434, Chr XII from 1022248-1019312, reverse complement, Verified ORF, "Silencing protein that interacts with Sir2p and Sir4p, and histone H3 and H4 tails, to establish a transcriptionally silent chromatin state; required for spreading of silenced chromatin; recruited to chromatin through interaction with Rap1p" |
| 3987 | YLR443W | ECM7 SGDID:S000004435, Chr XII from 1022622-1023968, Verified ORF, "Non-essential putative integral membrane protein; mutant has cell wall defects; transcription is induced under conditions of zinc deficiency" |
| 3988 | YLR445W | YLR445W SGDID:S000004437, Chr XII from 1024186-1024569,1024652-1024834, Uncharacterized ORF, "Putative protein of unknown function; transcription is regulated by Ume6p and induced in response to alpha factor" |
| 3989 | YLR446W | YLR446W SGDID:S000004438, Chr XII from 1025211-1026512, Uncharacterized ORF, "Putative protein of unknown function with similarity to hexokinases; transcript is upregulated during sporulation and the unfolded protein response; YLR446W is not an essential gene" |
| 3990 | YLR447C | VMA6 SGDID:S000004439, Chr XII from 1027890-1026853, reverse complement, Verified ORF, "Subunit d of the five-subunit V0 integral membrane domain of vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found in the endomembrane system; stabilizes VO subunits; required for V1 domain assembly on the vacuolar membrane" |
| 3991 | YLR448W | RPL6B SGDID:S000004440, Chr XII from 1028850-1028864,1029249-1029764, Verified ORF, "Protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Ap and to rat L6 ribosomal protein; binds to 5.8S rRNA" |
| 3992 | YLR449W | FPR4 SGDID:S000004441, Chr XII from 1030830-1032008, Verified ORF, "Peptidyl-prolyl cis-trans isomerase (PPIase) (proline isomerase) localized to the nucleus; catalyzes isomerization of proline residues in histones H3 and H4, which affects lysine methylation of those histones" |
| 3993 | YLR450W | HMG2 SGDID:S000004442, Chr XII from 1032624-1035761, Verified ORF, "One of two isozymes of HMG-CoA reductase that convert HMG-CoA to mevalonate, a rate-limiting step in sterol biosynthesis; overproduction induces assembly of peripheral ER membrane arrays and short nuclear-associated membrane stacks" |
| 3994 | YLR451W | LEU3 SGDID:S000004443, Chr XII from 1036090-1038750, Verified ORF, "Zinc-finger transcription factor that regulates genes involved in branched chain amino acid biosynthesis and ammonia assimilation; positively regulated by alpha-isopropylmalate, an intermediate in leucine biosynthesis" |
| 3995 | YLR452C | SST2 SGDID:S000004444, Chr XII from 1041364-1039268, reverse complement, Verified ORF, "GTPase-activating protein for Gpa1p, regulates desensitization to alpha factor pheromone; also required to prevent receptor-independent signaling of the mating pathway; member of the RGS (regulator of G-protein signaling) family" |
| 3996 | YLR453C | RIF2 SGDID:S000004445, Chr XII from 1042984-1041797, reverse complement, Verified ORF, "Protein that binds to the Rap1p C-terminus and acts synergistically with Rif1p to help control telomere length and establish telomeric silencing; deletion results in telomere elongation" |
| 3997 | YLR454W | YLR454W SGDID:S000004446, Chr XII from 1043996-1051882, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 3998 | YLR455W | YLR455W SGDID:S000004447, Chr XII from 1053627-1054541, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)" |
| 3999 | YLR456W | YLR456W SGDID:S000004448, Chr XII from 1055068-1055682, Uncharacterized ORF, "Putative protein of unknown function; null mutant displays increased resistance to antifungal agents gliotoxin, cycloheximide and H2O2" |
| 4000 | YLR457C | NBP1 SGDID:S000004449, Chr XII from 1056769-1055810, reverse complement, Verified ORF, "Spindle pole body (SPB) component, required for the insertion of the duplication plaque into the nuclear membrane during SPB duplication; essential for bipolar spindle formation; component of the Mps2p-Bbp1p complex" |
| 4001 | YLR459W | GAB1 SGDID:S000004451, Chr XII from 1057332-1058516, Verified ORF, "GPI transamidase subunit, involved in attachment of glycosylphosphatidylinositol (GPI) anchors to proteins; may have a role in recognition of the attachment signal or of the lipid portion of GPI" |
| 4002 | YLR460C | YLR460C SGDID:S000004452, Chr XII from 1060885-1059755, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, possibly up-regulated by iodine" |
| 4003 | YLR461W | PAU4 SGDID:S000004453, Chr XII from 1062917-1063279, Verified ORF, "Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme" |
| 4004 | YLR462W | YLR462W SGDID:S000004454, Chr XII from 1065954-1066562, Uncharacterized ORF, "Putative protein of unknown function with similarity to helicases; YLR462W is within the telomere on the right arm of chromosome XII" |
| 4005 | YLR464W | YLR464W SGDID:S000004456, Chr XII from 1066570-1067082,1067362-1067499, Uncharacterized ORF, "Putative protein of unknown function; intron is predicted but not detected experimentally; YLR464W overlaps the verified gene YRF1-4/YLR466W and two dubious ORFs YLR463C and YLR465C" |
| 4006 | YLR466C-B | YLR466C-B SGDID:S000028686, Chr XII from 1071708-1071592, reverse complement, Uncharacterized ORF, "Dubious open reading frame unlikely to encode a protein, based on available experimental and comparative sequence data" |
| 4007 | YLR466W | YRF1-4 SGDID:S000004458, Chr XII from 1067085-1071233, Verified ORF, "Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p" |
| 4008 | YLR467W | YRF1-5 SGDID:S000004459, Chr XII from 1072506-1077896, Verified ORF, "Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p" |
| 4009 | YML001W | YPT7 SGDID:S000004460, Chr XIII from 267174-267800, Verified ORF, "GTPase; GTP-binding protein of the rab family; required for homotypic fusion event in vacuole inheritance, for endosome-endosome fusion, similar to mammalian Rab7" |
| 4010 | YML002W | YML002W SGDID:S000004461, Chr XIII from 264541-266754, Uncharacterized ORF, "Putative protein of unknown function; expression induced by heat and by calcium shortage" |
| 4011 | YML003W | YML003W SGDID:S000004462, Chr XIII from 263483-264355, Uncharacterized ORF, "Putative protein of unknown function" |
| 4012 | YML004C | GLO1 SGDID:S000004463, Chr XIII from 262685-261705, reverse complement, Verified ORF, "Monomeric glyoxalase I, catalyzes the detoxification of methylglyoxal (a by-product of glycolysis) via condensation with glutathione to produce S-D-lactoylglutathione; expression regulated by methylglyoxal levels and osmotic stress" |
| 4013 | YML005W | TRM12 SGDID:S000004464, Chr XIII from 260221-261609, Verified ORF, "S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; required for wybutosine formation in phenylalanine-accepting tRNA" |
| 4014 | YML006C | GIS4 SGDID:S000004465, Chr XIII from 258416-256092, reverse complement, Verified ORF, "CAAX box containing protein of unknown function, proposed to be involved in the RAS/cAMP signaling pathway" |
| 4015 | YML007C-A | YML007C-A SGDID:S000007621, Chr XIII from 253272-253162, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria" |
| 4016 | YML007W | YAP1 SGDID:S000004466, Chr XIII from 253848-255800, Verified ORF, "Basic leucine zipper (bZIP) transcription factor required for oxidative stress tolerance; activated by H2O2 through the multistep formation of disulfide bonds and transit from the cytoplasm to the nucleus; mediates resistance to cadmium" |
| 4017 | YML008C | ERG6 SGDID:S000004467, Chr XIII from 252990-251839, reverse complement, Verified ORF, "Delta(24)-sterol C-methyltransferase, converts zymosterol to fecosterol in the ergosterol biosynthetic pathway by methylating position C-24; localized to both lipid particles and mitochondrial outer membrane" |
| 4018 | YML009C | MRPL39 SGDID:S000004468, Chr XIII from 251516-251304, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 4019 | YML010W | SPT5 SGDID:S000004470, Chr XIII from 247677-250868, Verified ORF, "Protein that forms a complex with Spt4p and mediates both activation and inhibition of transcription elongation; Spt4p-Spt5p complex also plays a role in pre-mRNA processing" |
| 4020 | YML011C | RAD33 SGDID:S000004472, Chr XIII from 247428-246895, reverse complement, Verified ORF, "Protein involved in nucleotide excision repair; green fluorescent protein (GFP)-fusion protein localizes to the nucleus" |
| 4021 | YML012W | ERV25 SGDID:S000004473, Chr XIII from 246116-246751, Verified ORF, "Protein that forms a heterotrimeric complex with Erp1, Erp2p, and Emp24, member of the p24 family involved in endoplasmic reticulum to Golgi transport" |
| 4022 | YML013W | UBX2 SGDID:S000004475, Chr XIII from 244149-245903, Verified ORF, "Protein involved in ER-associated protein degradation; proposed to coordinate the assembly of proteins involved in ERAD; contains a UBX (ubiquitin regulatory X) domain and a ubiquitin-associated (UBA) domain" |
| 4023 | YML014W | TRM9 SGDID:S000004476, Chr XIII from 243225-244064, Verified ORF, "tRNA methyltransferase, catalyzes esterification of modified uridine nucleotides in tRNAs, creating 5-methylcarbonylmethyluridine in tRNA(Arg3) and 5-methylcarbonylmethyl-2-thiouridine in tRNA(Glu); deletion confers resistance to zymocin" |
| 4024 | YML015C | TAF11 SGDID:S000004477, Chr XIII from 243029-241989, reverse complement, Verified ORF, "TFIID subunit (40 kDa), involved in RNA polymerase II transcription initiation, similar to histone H3 with atypical histone fold motif of Spt3-like transcription factors" |
| 4025 | YML016C | PPZ1 SGDID:S000004478, Chr XIII from 241536-239458, reverse complement, Verified ORF, "Serine/threonine protein phosphatase Z, isoform of Ppz2p; involved in regulation of potassium transport, which affects osmotic stability, cell cycle progression, and halotolerance" |
| 4026 | YML017W | PSP2 SGDID:S000004479, Chr XIII from 236588-236591,236954-238731, Verified ORF, "Asn rich cytoplasmic protein that contains RGG motifs; high-copy suppressor of group II intron-splicing defects of a mutation in MRS2 and of a conditional mutation in POL1 (DNA polymerase alpha); possible role in mitochondrial mRNA splicing" |
| 4027 | YML018C | YML018C SGDID:S000004480, Chr XIII from 235952-234771, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the membrane of the vacuole; physical interaction with Atg27p suggests a possible role in autophagy; YML018C is not an essential gene" |
| 4028 | YML019W | OST6 SGDID:S000004481, Chr XIII from 233457-234455, Verified ORF, "Subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; similar to and partially functionally redundant with Ost3p" |
| 4029 | YML020W | YML020W SGDID:S000004482, Chr XIII from 231149-233143, Uncharacterized ORF, "Putative protein of unknown function" |
| 4030 | YML021C | UNG1 SGDID:S000004483, Chr XIII from 230813-229734, reverse complement, Verified ORF, "Uracil-DNA glycosylase, required for repair of uracil in DNA formed by spontaneous cytosine deamination, not required for strand-specific mismatch repair, cell-cycle regulated, expressed in late G1, localizes to mitochondria and nucleus" |
| 4031 | YML022W | APT1 SGDID:S000004484, Chr XIII from 228937-229500, Verified ORF, "Adenine phosphoribosyltransferase, catalyzes the formation of AMP from adenine and 5-phosphoribosylpyrophosphate; involved in the salvage pathway of purine nucleotide biosynthesis" |
| 4032 | YML023C | NSE5 SGDID:S000004485, Chr XIII from 228664-226994, reverse complement, Verified ORF, "Essential subunit of the Mms21-Smc5-Smc6 complex; required for cell viability and DNA repair" |
| 4033 | YML024W | RPS17A SGDID:S000004486, Chr XIII from 225889-225891,226290-226697, Verified ORF, "Ribosomal protein 51 (rp51) of the small (40s) subunit; nearly identical to Rps17Bp and has similarity to rat S17 ribosomal protein" |
| 4034 | YML025C | YML6 SGDID:S000004487, Chr XIII from 225365-225339,225239-224406, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit, has similarity to E. coli L4 ribosomal protein and human mitoribosomal MRP-L4 protein; essential for viability, unlike most other mitoribosomal proteins" |
| 4035 | YML026C | RPS18B SGDID:S000004488, Chr XIII from 223828-223782,223380-222987, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps18Ap and has similarity to E. coli S13 and rat S18 ribosomal proteins" |
| 4036 | YML027W | YOX1 SGDID:S000004489, Chr XIII from 221406-222563, Verified ORF, "Homeodomain-containing transcriptional repressor, binds to Mcm1p and to early cell cycle boxes (ECBs) in the promoters of cell cycle-regulated genes expressed in M/G1 phase; expression is cell cycle-regulated; potential Cdc28p substrate" |
| 4037 | YML028W | TSA1 SGDID:S000004490, Chr XIII from 220138-220728, Verified ORF, "Thioredoxin peroxidase, acts as both a ribosome-associated and free cytoplasmic antioxidant; self-associates to form a high-molecular weight chaperone complex under oxidative stress; deletion results in mutator phenotype" |
| 4038 | YML029W | USA1 SGDID:S000004491, Chr XIII from 217362-219878, Verified ORF, "Protein involved in ER-associated protein degradation (ERAD); component of the Hrd1p complex; interacts with the U1 snRNP-specific protein, Snp1p" |
| 4039 | YML030W | YML030W SGDID:S000004492, Chr XIII from 216435-216914, Uncharacterized ORF, "Putative protein of unknown function; GFP-fusion protein localizes to mitochondria; null mutant is viable and displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth rate in minimal glycerol media" |
| 4040 | YML031W | NDC1 SGDID:S000004493, Chr XIII from 214189-216156, Verified ORF, "Nuclear envelope protein with multiple putative transmembrane domains, required for nuclear pore complex assembly and spindle pole body duplication; required for meiosis II" |
| 4041 | YML032C | RAD52 SGDID:S000004494, Chr XIII from 213930-212515, reverse complement, Verified ORF, "Protein that stimulates strand exchange by facilitating Rad51p binding to single-stranded DNA; anneals complementary single-stranded DNA; involved in the repair of double-strand breaks in DNA during vegetative growth and meiosis" |
| 4042 | YML034W | SRC1 SGDID:S000004497, Chr XIII from 209525-211444,211571-212155, Verified ORF, "Inner nuclear membrane (INM) protein with a putative role in sister chromatid segregation, potentially phosphorylated by Cdc28p; contains helix-extension-helix (HEH) motif, nuclear localization signal sequence" |
| 4043 | YML035C | AMD1 SGDID:S000004498, Chr XIII from 208860-206428, reverse complement, Verified ORF, "AMP deaminase, tetrameric enzyme that catalyzes the deamination of AMP to form IMP and ammonia; may be involved in regulation of intracellular adenine nucleotide pools" |
| 4044 | YML036W | CGI121 SGDID:S000004500, Chr XIII from 205642-206097,206204-206293, Verified ORF, "Protein involved in telomere uncapping and elongation as component of the KEOPS protein complex with Bud32p, Kae1p, Pcc1p, and Gon7p; also shown to be a component of the EKC protein complex; homolog of human CGI-121" |
| 4045 | YML037C | YML037C SGDID:S000004501, Chr XIII from 205408-204386, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with some characteristics of a transcriptional activator; may be a target of Dbf2p-Mob1p kinase; GFP-fusion protein co-localizes with clathrin-coated vesicles; YML037C is not an essential gene" |
| 4046 | YML038C | YMD8 SGDID:S000004502, Chr XIII from 204103-202775, reverse complement, Verified ORF, "Putative nucleotide sugar transporter, has similarity to Vrg4p" |
| 4047 | YML039W | YML039W SGDID:S000004503, Chr XIII from 196628-197932,197934-201896, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 4048 | YML040W | YML040W SGDID:S000004504, Chr XIII from 196628-197950, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 4049 | YML041C | VPS71 SGDID:S000004505, Chr XIII from 195755-194913, reverse complement, Verified ORF, "Nucleosome-binding component of the SWR1 complex, which exchanges histone variant H2AZ (Htz1p) for chromatin-bound histone H2A; required for vacuolar protein sorting" |
| 4050 | YML042W | CAT2 SGDID:S000004506, Chr XIII from 192788-194800, Verified ORF, "Carnitine acetyl-CoA transferase present in both mitochondria and peroxisomes, transfers activated acetyl groups to carnitine to form acetylcarnitine which can be shuttled across membranes" |
| 4051 | YML043C | RRN11 SGDID:S000004507, Chr XIII from 191767-190244, reverse complement, Verified ORF, "Protein required for rDNA transcription by RNA polymerase I, component of the core factor (CF) of rDNA transcription factor, which also contains Rrn6p and Rrn7p" |
| 4052 | YML045W | YML045W SGDID:S000004508, Chr XIII from 184461-185765,185767-189729, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 4053 | YML045W-A | YML045W-A SGDID:S000007381, Chr XIII from 184461-185783, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 4054 | YML046W | PRP39 SGDID:S000004509, Chr XIII from 181474-183363, Verified ORF, "U1 snRNP protein involved in splicing, contains multiple tetriatricopeptide repeats" |
| 4055 | YML047C | PRM6 SGDID:S000004510, Chr XIII from 181075-180017, reverse complement, Verified ORF, "Pheromone-regulated protein, predicted to have 2 transmembrane segments; regulated by Ste12p during mating" |
| 4056 | YML048W | GSF2 SGDID:S000004511, Chr XIII from 178426-179637, Verified ORF, "ER localized integral membrane protein that may promote secretion of certain hexose transporters, including Gal2p; involved in glucose-dependent repression" |
| 4057 | YML049C | RSE1 SGDID:S000004513, Chr XIII from 178305-174220, reverse complement, Verified ORF, "Protein involved in pre-mRNA splicing; component of the pre-spliceosome; associates with U2 snRNA; involved in ER to Golgi transport" |
| 4058 | YML050W | YML050W SGDID:S000004514, Chr XIII from 173139-174074, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene; null mutant displays increased frequency of mitochondrial genome loss (petite formation)" |
| 4059 | YML051W | GAL80 SGDID:S000004515, Chr XIII from 171594-172901, Verified ORF, "Transcriptional regulator involved in the repression of GAL genes in the absence of galactose; inhibits transcriptional activation by Gal4p; inhibition relieved by Gal3p or Gal1p binding" |
| 4060 | YML052W | SUR7 SGDID:S000004516, Chr XIII from 170402-171310, Verified ORF, "Putative integral membrane protein; component of eisosomes; associated with endocytosis, along with Pil1p and Lsp1p; sporulation and plasma membrane sphingolipid content are altered in mutants" |
| 4061 | YML053C | YML053C SGDID:S000004517, Chr XIII from 169754-169116, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus; YML053C is not an essential gene" |
| 4062 | YML054C | CYB2 SGDID:S000004518, Chr XIII from 167308-165533, reverse complement, Verified ORF, "Cytochrome b2 (L-lactate cytochrome-c oxidoreductase), component of the mitochondrial intermembrane space, required for lactate utilization; expression is repressed by glucose and anaerobic conditions" |
| 4063 | YML054C-A | YML054C-A SGDID:S000028573, Chr XIII from 167781-167623, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 4064 | YML055W | SPC2 SGDID:S000004519, Chr XIII from 164790-165326, Verified ORF, "Subunit of signal peptidase complex (Spc1p, Spc2p, Spc3p, Sec11p), which catalyzes cleavage of N-terminal signal sequences of proteins targeted to the secretory pathway; homologous to mammalian SPC25" |
| 4065 | YML056C | IMD4 SGDID:S000004520, Chr XIII from 164176-163717,163308-162194, reverse complement, Verified ORF, "Inosine monophosphate dehydrogenase, catalyzes the first step of GMP biosynthesis, member of a four-gene family in S. cerevisiae, constitutively expressed" |
| 4066 | YML057W | CMP2 SGDID:S000004521, Chr XIII from 160180-161994, Verified ORF, "Calcineurin A; one isoform (the other is CNA1) of the catalytic subunit of calcineurin, a Ca++/calmodulin-regulated protein phosphatase which regulates Crz1p (a stress-response transcription factor), the other calcineurin subunit is CNB1" |
| 4067 | YML058W | SML1 SGDID:S000004523, Chr XIII from 159383-159697, Verified ORF, "Ribonucleotide reductase inhibitor involved in regulating dNTP production; regulated by Mec1p and Rad53p during DNA damage and S phase" |
| 4068 | YML058W-A | HUG1 SGDID:S000007472, Chr XIII from 158760-158966, Verified ORF, "Protein involved in the Mec1p-mediated checkpoint pathway that responds to DNA damage or replication arrest, transcription is induced by DNA damage" |
| 4069 | YML059C | NTE1 SGDID:S000004524, Chr XIII from 158258-153219, reverse complement, Verified ORF, "Serine esterase that deacylates exogenous lysophospholipids, homolog of human neuropathy target esterase (NTE); mammalian NTE1 deacylates phosphatidylcholine to glycerophosphocholine" |
| 4070 | YML060W | OGG1 SGDID:S000004525, Chr XIII from 151871-153001, Verified ORF, "Mitochondrial glycosylase/lyase that specifically excises 7,8-dihydro-8-oxoguanine residues located opposite cytosine or thymine residues in DNA, repairs oxidative damage to mitochondrial DNA" |
| 4071 | YML061C | PIF1 SGDID:S000004526, Chr XIII from 151532-148953, reverse complement, Verified ORF, "DNA helicase involved in telomere formation and elongation; acts as a catalytic inhibitor of telomerase; also plays a role in repair and recombination of mitochondrial DNA" |
| 4072 | YML062C | MFT1 SGDID:S000004527, Chr XIII from 148683-147505, reverse complement, Verified ORF, "Subunit of the THO complex, which is a nuclear complex comprised of Hpr1p, Mft1p, Rlr1p, and Thp2p, that is involved in transcription elongation and mitotic recombination; involved in telomere maintenance" |
| 4073 | YML063W | RPS1B SGDID:S000004528, Chr XIII from 146482-147249, Verified ORF, "Ribosomal protein 10 (rp10) of the small (40S) subunit; nearly identical to Rps1Ap and has similarity to rat S3a ribosomal protein" |
| 4074 | YML064C | TEM1 SGDID:S000004529, Chr XIII from 145876-145139, reverse complement, Verified ORF, "GTP-binding protein of the ras superfamily involved in termination of M-phase; controls actomyosin and septin dynamics during cytokinesis" |
| 4075 | YML065W | ORC1 SGDID:S000004530, Chr XIII from 142210-144954, Verified ORF, "Largest subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; exhibits ATPase activity" |
| 4076 | YML066C | SMA2 SGDID:S000004531, Chr XIII from 141533-140424, reverse complement, Verified ORF, "Protein of unknown function involved in the assembly of the prospore membrane during sporulation" |
| 4077 | YML067C | ERV41 SGDID:S000004532, Chr XIII from 140214-140184,140090-139063, reverse complement, Verified ORF, "Protein localized to COPII-coated vesicles, forms a complex with Erv46p; involved in the membrane fusion stage of transport; has homology to human ERGIC2 (PTX1) protein" |
| 4078 | YML068W | ITT1 SGDID:S000004533, Chr XIII from 137550-138944, Verified ORF, "Protein that modulates the efficiency of translation termination, interacts with translation release factors eRF1 (Sup45p) and eRF3 (Sup35p) in vitro, contains a zinc finger domain characteristic of the TRIAD class of proteins" |
| 4079 | YML069W | POB3 SGDID:S000004534, Chr XIII from 135500-137158, Verified ORF, "Subunit of the heterodimeric FACT complex (Spt16p-Pob3p), which facilitates RNA Pol II transcription elongation through nucleosomes by destabilizing and then reassembling nucleosome structure; interacts with DNA polymerase alpha (Pol1p)" |
| 4080 | YML070W | DAK1 SGDID:S000004535, Chr XIII from 133475-135229, Verified ORF, "Dihydroxyacetone kinase, required for detoxification of dihydroxyacetone (DHA); involved in stress adaptation" |
| 4081 | YML071C | COG8 SGDID:S000004536, Chr XIII from 131572-129749, reverse complement, Verified ORF, "Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" |
| 4082 | YML072C | TCB3 SGDID:S000004537, Chr XIII from 129367-124730, reverse complement, Verified ORF, "Lipid-binding protein, localized to the bud via specific mRNA transport; non-tagged protein detected in a phosphorylated state in mitochondria; GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact" |
| 4083 | YML073C | RPL6A SGDID:S000004538, Chr XIII from 124172-124158,123742-123227, reverse complement, Verified ORF, "N-terminally acetylated protein component of the large (60S) ribosomal subunit, has similarity to Rpl6Bp and to rat L6 ribosomal protein; binds to 5.8S rRNA" |
| 4084 | YML074C | FPR3 SGDID:S000004539, Chr XIII from 121324-120089, reverse complement, Verified ORF, "Nucleolar peptidyl-prolyl cis-trans isomerase (PPIase); FK506 binding protein; phosphorylated by casein kinase II (Cka1p-Cka2p-Ckb1p-Ckb2p) and dephosphorylated by Ptp1p" |
| 4085 | YML075C | HMG1 SGDID:S000004540, Chr XIII from 118898-115734, reverse complement, Verified ORF, "One of two isozymes of HMG-CoA reductase that catalyzes the conversion of HMG-CoA to mevalonate, which is a rate-limiting step in sterol biosynthesis; localizes to the nuclear envelope; overproduction induces the formation of karmellae" |
| 4086 | YML076C | WAR1 SGDID:S000004541, Chr XIII from 115347-112513, reverse complement, Verified ORF, "Homodimeric Zn2Cys6 zinc finger transcription factor; binds to a weak acid response element to induce transcription of PDR12 and FUN34, encoding an acid transporter and a putative ammonia transporter, respectively" |
| 4087 | YML077W | BET5 SGDID:S000004542, Chr XIII from 111865-112344, Verified ORF, "Component of the TRAPP (transport protein particle) complex, which plays an essential role in the vesicular transport from endoplasmic reticulum to Golgi" |
| 4088 | YML078W | CPR3 SGDID:S000004543, Chr XIII from 111002-111550, Verified ORF, "Mitochondrial peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; involved in protein refolding after import into mitochondria" |
| 4089 | YML079W | YML079W SGDID:S000004544, Chr XIII from 110247-110852, Uncharacterized ORF, "Non-essential protein of unknown function with structural resemblance to plant storage and ligand binding proteins (canavalin, glycinin, auxin binding protein) and to some enzymes (epimerase, germin); localizes to the nucleus and cytoplasm" |
| 4090 | YML080W | DUS1 SGDID:S000004545, Chr XIII from 108806-110077, Verified ORF, "Dihydrouridine synthase, member of a widespread family of conserved proteins including Smm1p, Dus3p, and Dus4p; modifies pre-tRNA(Phe) at U17" |
| 4091 | YML081C-A | ATP18 SGDID:S000007247, Chr XIII from 104162-103983, reverse complement, Verified ORF, "Subunit of the mitochondrial F1F0 ATP synthase, which is a large enzyme complex required for ATP synthesis; termed subunit I or subunit j; does not correspond to known ATP synthase subunits in other organisms" |
| 4092 | YML081W | YML081W SGDID:S000004546, Chr XIII from 104777-108532, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YML081w is not an essential gene" |
| 4093 | YML082W | YML082W SGDID:S000004547, Chr XIII from 101862-103811, Uncharacterized ORF, "Putative protein predicted to have carbon-sulfur lyase activity; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and the cytoplasm; YNML082W is not an essential gene" |
| 4094 | YML083C | YML083C SGDID:S000004548, Chr XIII from 101050-99794, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; strong increase in transcript abundance during anaerobic growth compared to aerobic growth; cells deleted for YML083C do not exhibit growth defects in anerobic or anaerobic conditions" |
| 4095 | YML085C | TUB1 SGDID:S000004550, Chr XIII from 99400-99376,99259-97941, reverse complement, Verified ORF, "Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules" |
| 4096 | YML086C | ALO1 SGDID:S000004551, Chr XIII from 97371-95791, reverse complement, Verified ORF, "D-Arabinono-1,4-lactone oxidase, catalyzes the final step in biosynthesis of D-erythroascorbic acid, which is protective against oxidative stress" |
| 4097 | YML087C | YML087C SGDID:S000004552, Chr XIII from 95369-94431, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; highly conserved across species and orthologous to human CYB5R4; null mutant shows increased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media" |
| 4098 | YML088W | UFO1 SGDID:S000004553, Chr XIII from 92235-94241, Verified ORF, "F-box receptor protein, subunit of the Skp1-Cdc53-F-box receptor (SCF) E3 ubiquitin ligase complex; binds to phosphorylated Ho endonuclease, allowing its ubiquitylation by SCF and subsequent degradation" |
| 4099 | YML091C | RPM2 SGDID:S000004556, Chr XIII from 90731-87123, reverse complement, Verified ORF, "Protein subunit of mitochondrial RNase P, has roles in nuclear transcription, cytoplasmic and mitochondrial RNA processing, and mitochondrial translation; distributed to mitochondria, cytoplasmic processing bodies, and the nucleus" |
| 4100 | YML092C | PRE8 SGDID:S000004557, Chr XIII from 86739-85987, reverse complement, Verified ORF, "Alpha 2 subunit of the 20S proteasome" |
| 4101 | YML093W | UTP14 SGDID:S000004558, Chr XIII from 83090-85789, Verified ORF, "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" |
| 4102 | YML094W | GIM5 SGDID:S000004559, Chr XIII from 82275-82290,82374-82849, Verified ORF, "Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it" |
| 4103 | YML095C | RAD10 SGDID:S000004560, Chr XIII from 82113-81481, reverse complement, Verified ORF, "Single-stranded DNA endonuclease (with Rad1p), cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human ERCC1 protein" |
| 4104 | YML096W | YML096W SGDID:S000004562, Chr XIII from 79909-81486, Uncharacterized ORF, "Putative protein of unknown function with similarity to asparagine synthetases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YML096W is not an essential gene and partially overlaps the verified gene RAD10" |
| 4105 | YML097C | VPS9 SGDID:S000004563, Chr XIII from 79690-78335, reverse complement, Verified ORF, "A guanine nucleotide exchange factor involved in vesicle-mediated vacuolar protein transport; specifically stimulates the intrinsic guanine nucleotide exchange activity of Vps21p/Rab5: similar to mammalian ras inhibitors; binds ubiquitin" |
| 4106 | YML098W | TAF13 SGDID:S000004564, Chr XIII from 77267-77770, Verified ORF, "TFIID subunit (19 kDa), involved in RNA polymerase II transcription initiation, similar to histone H4 with atypical histone fold motif of Spt3-like transcription factors" |
| 4107 | YML099C | ARG81 SGDID:S000004565, Chr XIII from 77040-74398, reverse complement, Verified ORF, "Zinc-finger transcription factor of the Zn(2)-Cys(6) binuclear cluster domain type, involved in the regulation of arginine-responsive genes; acts with Arg80p and Arg82p" |
| 4108 | YML100W | TSL1 SGDID:S000004566, Chr XIII from 70624-73920, Verified ORF, "Large subunit of trehalose 6-phosphate synthase (Tps1p)/phosphatase (Tps2p) complex, which converts uridine-5'-diphosphoglucose and glucose 6-phosphate to trehalose, homologous to Tps3p and may share function" |
| 4109 | YML100W-A | YML100W-A SGDID:S000028688, Chr XIII from 70138-70311, Uncharacterized ORF, "Putative protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 4110 | YML101C | CUE4 SGDID:S000004568, Chr XIII from 70088-69735, reverse complement, Verified ORF, "Protein of unknown function; has a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination" |
| 4111 | YML102W | CAC2 SGDID:S000004570, Chr XIII from 68294-69700, Verified ORF, "Component of the chromatin assembly complex (with Rlf2p and Msi1p) that assembles newly synthesized histones onto recently replicated DNA, required for building functional kinetochores, conserved from yeast to humans" |
| 4112 | YML103C | NUP188 SGDID:S000004571, Chr XIII from 67549-62582, reverse complement, Verified ORF, "Subunit of the nuclear pore complex (NPC), involved in the structural organization of the complex and of the nuclear envelope, also involved in nuclear envelope permeability, interacts with Pom152p and Nic96p" |
| 4113 | YML104C | MDM1 SGDID:S000004572, Chr XIII from 62322-58939, reverse complement, Verified ORF, "Intermediate filament protein, required for nuclear and mitochondrial transmission to daughter buds; contains a Phox homology (PX) domain and specifically binds phosphatidylinositol 3-phosphate (PtdIns-3-P)" |
| 4114 | YML105C | SEC65 SGDID:S000004573, Chr XIII from 58687-57866, reverse complement, Verified ORF, "Subunit of the signal recognition particle (SRP), involved in protein targeting to the ER; interacts with Srp54p; homolog of mammalian SRP19" |
| 4115 | YML106W | URA5 SGDID:S000004574, Chr XIII from 56773-57453, Verified ORF, "Major orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; minor OPRTase encoded by URA10" |
| 4116 | YML107C | PML39 SGDID:S000004575, Chr XIII from 56269-55265, reverse complement, Verified ORF, "Protein required for nuclear retention of unspliced pre-mRNAs along with Mlp1p and Pml1p; anchored to nuclear pore complex via Mlp1p and Mlp2p; found with the subset of nuclear pores farthest from the nucleolus; may interact with ribosomes" |
| 4117 | YML108W | YML108W SGDID:S000004576, Chr XIII from 54793-55110, Uncharacterized ORF, "Putative protein of unknown function whose structure defines a new subfamily of the split beta-alpha-beta sandwiches; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YML108W is not an essential gene" |
| 4118 | YML109W | ZDS2 SGDID:S000004577, Chr XIII from 51640-54468, Verified ORF, "Protein that interacts with silencing proteins at the telomere, involved in transcriptional silencing; paralog of Zds1p" |
| 4119 | YML110C | COQ5 SGDID:S000004578, Chr XIII from 50954-50031, reverse complement, Verified ORF, "2-hexaprenyl-6-methoxy-1,4-benzoquinone methyltransferase, involved in ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with other ubiquinone biosynthetic enzymes" |
| 4120 | YML111W | BUL2 SGDID:S000004579, Chr XIII from 46942-49704, Verified ORF, "Component of the Rsp5p E3-ubiquitin ligase complex, involved in intracellular amino acid permease sorting, functions in heat shock element mediated gene expression, essential for growth in stress conditions, functional homolog of BUL1" |
| 4121 | YML112W | CTK3 SGDID:S000004580, Chr XIII from 45063-45953, Verified ORF, "Gamma subunit of C-terminal domain kinase I (CTDK-I), which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit (Rpo21p) to affect both transcription and pre-mRNA 3' end processing" |
| 4122 | YML113W | DAT1 SGDID:S000004581, Chr XIII from 44045-44791, Verified ORF, "DNA binding protein that recognizes oligo(dA).oligo(dT) tracts; Arg side chain in its N-terminal pentad Gly-Arg-Lys-Pro-Gly repeat is required for DNA-binding; not essential for viability" |
| 4123 | YML114C | TAF8 SGDID:S000004582, Chr XIII from 43575-42043, reverse complement, Verified ORF, "TFIID subunit (65 kDa), involved in RNA polymerase II transcription initiation" |
| 4124 | YML115C | VAN1 SGDID:S000004583, Chr XIII from 41794-40187, reverse complement, Verified ORF, "Component of the mannan polymerase I, which contains Van1p and Mnn9p and is involved in the first steps of mannan synthesis; mutants are vanadate-resistant" |
| 4125 | YML116W | ATR1 SGDID:S000004584, Chr XIII from 38196-39824, Verified ORF, "Multidrug efflux pump of the major facilitator superfamily, required for resistance to aminotriazole and 4-nitroquinoline-N-oxide" |
| 4126 | YML117W | NAB6 SGDID:S000004585, Chr XIII from 34243-37647, Verified ORF, "Putative RNA-binding protein, based on computational analysis of large-scale protein-protein interaction data" |
| 4127 | YML118W | NGL3 SGDID:S000004587, Chr XIII from 32334-33851, Verified ORF, "Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; similar to Ngl1p and Ngl2p" |
| 4128 | YML119W | YML119W SGDID:S000004588, Chr XIII from 30611-31684, Uncharacterized ORF, "Putative protein of unknown funtion; YML119W is not an essential gene; potential Cdc28p substrate" |
| 4129 | YML120C | NDI1 SGDID:S000004589, Chr XIII from 29807-28266, reverse complement, Verified ORF, "NADH:ubiquinone oxidoreductase, transfers electrons from NADH to ubiquinone in the respiratory chain but does not pump protons, in contrast to the higher eukaryotic multisubunit respiratory complex I; phosphorylated; homolog of human AMID" |
| 4130 | YML121W | GTR1 SGDID:S000004590, Chr XIII from 26930-27862, Verified ORF, "Cytoplasmic GTP binding protein and negative regulator of the Ran/Tc4 GTPase cycle; component of GSE complex, which is required for sorting of Gap1p; involved in phosphate transport and telomeric silencing; similar to human RagA and RagB" |
| 4131 | YML123C | PHO84 SGDID:S000004592, Chr XIII from 25801-24038, reverse complement, Verified ORF, "High-affinity inorganic phosphate (Pi) transporter and low-affinity manganese transporter; regulated by Pho4p and Spt7p; mutation confers resistance to arsenate; exit from the ER during maturation requires Pho86p" |
| 4132 | YML124C | TUB3 SGDID:S000004593, Chr XIII from 23684-23660,23361-22049, reverse complement, Verified ORF, "Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p" |
| 4133 | YML125C | PGA3 SGDID:S000004594, Chr XIII from 21700-20762, reverse complement, Verified ORF, "Essential protein required for maturation of Gas1p and Pho8p, proposed to be involved in protein trafficking; GFP-fusion protein localizes to the endoplasmic reticulum; null mutants have a cell separation defect" |
| 4134 | YML126C | ERG13 SGDID:S000004595, Chr XIII from 20536-19061, reverse complement, Verified ORF, "3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) synthase, catalyzes the formation of HMG-CoA from acetyl-CoA and acetoacetyl-CoA; involved in the second step in mevalonate biosynthesis" |
| 4135 | YML127W | RSC9 SGDID:S000004596, Chr XIII from 17065-18810, Verified ORF, "Component of the RSC chromatin remodeling complex; DNA-binding protein involved in the synthesis of rRNA and in transcriptional repression and activation of genes regulated by the Target of Rapamycin (TOR) pathway" |
| 4136 | YML128C | MSC1 SGDID:S000004597, Chr XIII from 16677-15136, reverse complement, Verified ORF, "Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria and is phosphorylated" |
| 4137 | YML129C | COX14 SGDID:S000004598, Chr XIII from 14754-14542, reverse complement, Verified ORF, "Mitochondrial membrane protein, involved in translational regulation of Cox1p and assembly of cytochrome c oxidase (complex IV); associates with complex IV assembly intermediates and complex III/complex IV supercomplexes" |
| 4138 | YML130C | ERO1 SGDID:S000004599, Chr XIII from 13175-11484, reverse complement, Verified ORF, "Thiol oxidase required for oxidative protein folding in the endoplasmic reticulum" |
| 4139 | YML131W | YML131W SGDID:S000004600, Chr XIII from 10199-11296, Uncharacterized ORF, "Putative protein of unknown function with similarity to oxidoreductases; HOG1 and SKO1-dependent mRNA expression is induced after osmotic shock; GFP-fusion protein localizes to the cytoplasm and is induced by the DNA-damaging agent MMS" |
| 4140 | YML132W | COS3 SGDID:S000004601, Chr XIII from 7244-8383, Verified ORF, "Protein involved in salt resistance; interacts with sodium:hydrogen antiporter Nha1p; member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" |
| 4141 | YML133C | YML133C SGDID:S000004602, Chr XIII from 4684-3891,3791-461, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with similarity to helicases; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YML133C contains an intron" |
| 4142 | YMR001C | CDC5 SGDID:S000004603, Chr XIII from 271136-269019, reverse complement, Verified ORF, "Polo-like kinase with similarity to Xenopus Plx1 and S. pombe Plo1p; found at bud neck, nucleus and SPBs; has multiple functions in mitosis and cytokinesis through phosphorylation of substrates; may be a Cdc28p substrate" |
| 4143 | YMR001C-A | YMR001C-A SGDID:S000028691, Chr XIII from 271577-271347, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 4144 | YMR002W | MIC17 SGDID:S000004604, Chr XIII from 272193-272663, Verified ORF, "Mitochondrial intermembrane space cysteine motif protein; MIC17 is not an essential gene" |
| 4145 | YMR003W | YMR003W SGDID:S000004605, Chr XIII from 273118-273714, Uncharacterized ORF, "Protein of unknown function; GFP-fusion protein localizes to the mitochondria; null mutant is viable and displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media" |
| 4146 | YMR004W | MVP1 SGDID:S000004606, Chr XIII from 274017-275552, Verified ORF, "Protein required for sorting proteins to the vacuole; overproduction of Mvp1p suppresses several dominant VPS1 mutations; Mvp1p and Vps1p act in concert to promote membrane traffic to the vacuole" |
| 4147 | YMR005W | TAF4 SGDID:S000004607, Chr XIII from 276045-277211, Verified ORF, "TFIID subunit (48 kDa), involved in RNA polymerase II transcription initiation; potential Cdc28p substrate" |
| 4148 | YMR006C | PLB2 SGDID:S000004608, Chr XIII from 279681-277561, reverse complement, Verified ORF, "Phospholipase B (lysophospholipase) involved in phospholipid metabolism; displays transacylase activity in vitro; overproduction confers resistance to lysophosphatidylcholine" |
| 4149 | YMR008C | PLB1 SGDID:S000004610, Chr XIII from 282584-280590, reverse complement, Verified ORF, "Phospholipase B (lysophospholipase) involved in lipid metabolism, required for deacylation of phosphatidylcholine and phosphatidylethanolamine but not phosphatidylinositol" |
| 4150 | YMR009W | ADI1 SGDID:S000004611, Chr XIII from 284101-284640, Verified ORF, "Acireductone dioxygenease involved in the methionine salvage pathway; ortholog of human MTCBP-1; transcribed with YMR010W and regulated post-transcriptionally by RNase III (Rnt1p) cleavage; ADI1 mRNA is induced in heat shock conditions" |
| 4151 | YMR010W | YMR010W SGDID:S000004612, Chr XIII from 285099-286316, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YMR010W is not an essential gene; YMR010W mRNA is transcribed with ADI1" |
| 4152 | YMR011W | HXT2 SGDID:S000004613, Chr XIII from 288078-289703, Verified ORF, "High-affinity glucose transporter of the major facilitator superfamily, expression is induced by low levels of glucose and repressed by high levels of glucose" |
| 4153 | YMR012W | CLU1 SGDID:S000004614, Chr XIII from 291133-294966, Verified ORF, "eIF3 component of unknown function; deletion causes defects in mitochondrial organization but not in growth or translation initiation, can rescue cytokinesis and mitochondrial organization defects of the Dictyostelium cluA- mutant" |
| 4154 | YMR013C | SEC59 SGDID:S000004615, Chr XIII from 296737-295178, reverse complement, Verified ORF, "Dolichol kinase, catalyzes the terminal step in dolichyl monophosphate (Dol-P) biosynthesis; required for viability and for normal rates of lipid intermediate synthesis and protein N-glycosylation" |
| 4155 | YMR014W | BUD22 SGDID:S000004616, Chr XIII from 298867-300426, Verified ORF, "Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern" |
| 4156 | YMR015C | ERG5 SGDID:S000004617, Chr XIII from 302484-300868, reverse complement, Verified ORF, "C-22 sterol desaturase, a cytochrome P450 enzyme that catalyzes the formation of the C-22(23) double bond in the sterol side chain in ergosterol biosynthesis; may be a target of azole antifungal drugs" |
| 4157 | YMR016C | SOK2 SGDID:S000004618, Chr XIII from 305592-303235, reverse complement, Verified ORF, "Nuclear protein that plays a regulatory role in the cyclic AMP (cAMP)-dependent protein kinase (PKA) signal transduction pathway; negatively regulates pseudohyphal differentiation; homologous to several transcription factors" |
| 4158 | YMR017W | SPO20 SGDID:S000004619, Chr XIII from 307488-308681, Verified ORF, "Meiosis-specific subunit of the t-SNARE complex, required for prospore membrane formation during sporulation; similar to but not functionally redundant with Sec9p; SNAP-25 homolog" |
| 4159 | YMR018W | YMR018W SGDID:S000004620, Chr XIII from 310207-311751, Uncharacterized ORF, "Putative protein of unknown function with similarity to human PEX5Rp (peroxin protein 5 related protein); transcription increases during colony development similar to genes involved in peroxisome biogenesis; YMR018W is not an essential gene" |
| 4160 | YMR019W | STB4 SGDID:S000004621, Chr XIII from 312155-315004, Verified ORF, "Protein that binds Sin3p in a two-hybrid assay; contains a Zn(II)2Cys6 zinc finger domain characteristic of DNA-binding proteins" |
| 4161 | YMR020W | FMS1 SGDID:S000004622, Chr XIII from 315376-316902, Verified ORF, "Polyamine oxidase, converts spermine to spermidine, which is required for the essential hypusination modification of translation factor eIF-5A; also involved in pantothenic acid biosynthesis" |
| 4162 | YMR021C | MAC1 SGDID:S000004623, Chr XIII from 318417-317164, reverse complement, Verified ORF, "Copper-sensing transcription factor involved in regulation of genes required for high affinity copper transport" |
| 4163 | YMR022W | UBC7 SGDID:S000004624, Chr XIII from 318679-319176, Verified ORF, "Ubiquitin conjugating enzyme, involved in the ER-associated protein degradation pathway; requires Cue1p for recruitment to the ER membrane; proposed to be involved in chromatin assembly" |
| 4164 | YMR023C | MSS1 SGDID:S000004625, Chr XIII from 321016-319436, reverse complement, Verified ORF, "Mitochondrial protein, forms a heterodimer complex with Mto1p that performs the 5-carboxymethylaminomethyl modification of the wobble uridine base in mitochondrial tRNAs; similar to human GTPBP3" |
| 4165 | YMR024W | MRPL3 SGDID:S000004626, Chr XIII from 321874-323046, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 4166 | YMR025W | CSI1 SGDID:S000004627, Chr XIII from 323299-324186, Verified ORF, "Subunit of the Cop9 signalosome, which is required for deneddylation, or removal of the ubiquitin-like protein Rub1p from Cdc53p (cullin); involved in adaptation to pheromone signaling" |
| 4167 | YMR026C | PEX12 SGDID:S000004628, Chr XIII from 325434-324235, reverse complement, Verified ORF, "C3HC4-type RING-finger peroxisomal membrane peroxin required for peroxisome biogenesis and peroxisomal matrix protein import; forms translocation subcomplex with Pex2p and Pex10p; mutations in human homolog cause peroxisomal disorders" |
| 4168 | YMR027W | YMR027W SGDID:S000004629, Chr XIII from 325876-327288, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR027W is not an essential gene" |
| 4169 | YMR028W | TAP42 SGDID:S000004630, Chr XIII from 327481-328581, Verified ORF, "Essential protein involved in the TOR signaling pathway; physically associates with the protein phosphatase 2A and the SIT4 protein phosphatase catalytic subunits" |
| 4170 | YMR029C | FAR8 SGDID:S000004631, Chr XIII from 330230-328659, reverse complement, Verified ORF, "Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far7p, Far9p, Far10p, and Far11p" |
| 4171 | YMR030W | RSF1 SGDID:S000004632, Chr XIII from 330792-331922, Verified ORF, "Protein required for respiratory growth; localized to both the nucleus and mitochondrion; mutant displays decreased transcription of specific nuclear and mitochondrial genes whose products are involved in respiratory growth" |
| 4172 | YMR030W-A | YMR030W-A SGDID:S000028574, Chr XIII from 337312-337602, Uncharacterized ORF, "Putative protein of unknown function" |
| 4173 | YMR031C | YMR031C SGDID:S000004633, Chr XIII from 334742-332211, reverse complement, Uncharacterized ORF, "Protein of unknown function with similarity to Ykl050cp and Uso1p; the authentic, non-tagged protein is detected in a phosphorylated state in highly purified mitochondria in high-throughput studies; YMR031C is not an essential gene" |
| 4174 | YMR032W | HOF1 SGDID:S000004635, Chr XIII from 335297-337306, Verified ORF, "Bud neck-localized, SH3 domain-containing protein required for cytokinesis; regulates actomyosin ring dynamics and septin localization; interacts with the formins, Bni1p and Bnr1p, and with Cyk3p, Vrp1p, and Bni5p" |
| 4175 | YMR033W | ARP9 SGDID:S000004636, Chr XIII from 337787-337816,337903-339276, Verified ORF, "Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation" |
| 4176 | YMR034C | YMR034C SGDID:S000004637, Chr XIII from 340721-339417, reverse complement, Uncharacterized ORF, "Putative transporter, member of the SLC10 carrier family; identified in a transposon mutagenesis screen as a gene involved in azole resistance; YMR034C is not an essential gene" |
| 4177 | YMR035W | IMP2 SGDID:S000004638, Chr XIII from 341141-341674, Verified ORF, "Catalytic subunit of the mitochondrial inner membrane peptidase complex, required for maturation of mitochondrial proteins of the intermembrane space; complex contains Imp1p and Imp2p (both catalytic subunits), and Som1p" |
| 4178 | YMR036C | MIH1 SGDID:S000004639, Chr XIII from 343519-341855, reverse complement, Verified ORF, "Protein tyrosine phosphatase involved in cell cycle control; regulates the phosphorylation state of Cdc28p; homolog of S. pombe cdc25" |
| 4179 | YMR037C | MSN2 SGDID:S000004640, Chr XIII from 346516-344402, reverse complement, Verified ORF, "Transcriptional activator related to Msn4p; activated in stress conditions, which results in translocation from the cytoplasm to the nucleus; binds DNA at stress response elements of responsive genes, inducing gene expression" |
| 4180 | YMR038C | CCS1 SGDID:S000004641, Chr XIII from 348259-347510, reverse complement, Verified ORF, "Copper chaperone for superoxide dismutase Sod1p, involved in oxidative stress protection; Met-X-Cys-X2-Cys motif within the N-terminal portion is involved in insertion of copper into Sod1p under conditions of copper deprivation" |
| 4181 | YMR039C | SUB1 SGDID:S000004642, Chr XIII from 349521-348643, reverse complement, Verified ORF, "Transcriptional coactivator, facilitates elongation by influencing enzymes that modify RNAP II, acts in a peroxide resistance pathway involving Rad2p; suppressor of TFIIB mutations" |
| 4182 | YMR040W | YET2 SGDID:S000004643, Chr XIII from 350380-350862, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; homolog of human BAP31 protein" |
| 4183 | YMR041C | ARA2 SGDID:S000004644, Chr XIII from 351972-350965, reverse complement, Verified ORF, "NAD-dependent arabinose dehydrogenase, involved in biosynthesis of erythroascorbic acid; similar to plant L-galactose dehydrogenase" |
| 4184 | YMR042W | ARG80 SGDID:S000004645, Chr XIII from 352602-353135, Verified ORF, "Transcription factor involved in regulation of arginine-responsive genes; acts with Arg81p and Arg82p" |
| 4185 | YMR043W | MCM1 SGDID:S000004646, Chr XIII from 353870-354730, Verified ORF, "Transcription factor involved in cell-type-specific transcription and pheromone response; plays a central role in the formation of both repressor and activator complexes" |
| 4186 | YMR044W | IOC4 SGDID:S000004647, Chr XIII from 355383-356810, Verified ORF, "Member of a complex (Isw1b) with Isw1p and Ioc2p that exhibits nucleosome-stimulated ATPase activity and acts within coding regions to coordinate transcription elongation with termination and processing, contains a PWWP motif" |
| 4187 | YMR045C | YMR045C SGDID:S000004648, Chr XIII from 362626-361322,361320-357358, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 4188 | YMR046C | YMR046C SGDID:S000004649, Chr XIII from 362626-361304, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 4189 | YMR047C | NUP116 SGDID:S000004650, Chr XIII from 366704-363363, reverse complement, Verified ORF, "Subunit of the nuclear pore complex (NPC) that is localized to both sides of the pore; contains a repetitive GLFG motif that interacts with mRNA export factor Mex67p and with karyopherin Kap95p; homologous to Nup100p" |
| 4190 | YMR048W | CSM3 SGDID:S000004651, Chr XIII from 366980-367933, Verified ORF, "Protein required for accurate chromosome segregation during meiosis" |
| 4191 | YMR049C | ERB1 SGDID:S000004652, Chr XIII from 370516-368093, reverse complement, Verified ORF, "Protein required for maturation of the 25S and 5.8S ribosomal RNAs; constituent of 66S pre-ribosomal particles; homologous to mammalian Bop1" |
| 4192 | YMR050C | YMR050C SGDID:S000004653, Chr XIII from 378324-377020,377018-373056, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 4193 | YMR051C | YMR051C SGDID:S000004654, Chr XIII from 378324-377002, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 4194 | YMR052W | FAR3 SGDID:S000004656, Chr XIII from 379585-380199, Verified ORF, "Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far7p, Far8p, Far9p, Far10p, and Far11p" |
| 4195 | YMR053C | STB2 SGDID:S000004657, Chr XIII from 382897-380345, reverse complement, Verified ORF, "Protein that interacts with Sin3p in a two-hybrid assay and is part of a large protein complex with Sin3p and Stb1p" |
| 4196 | YMR054W | STV1 SGDID:S000004658, Chr XIII from 383302-385974, Verified ORF, "Subunit a of the vacuolar-ATPase V0 domain, one of two isoforms (Stv1p and Vph1p); Stv1p is located in V-ATPase complexes of the Golgi and endosomes while Vph1p is located in V-ATPase complexes of the vacuole" |
| 4197 | YMR055C | BUB2 SGDID:S000004659, Chr XIII from 387020-386100, reverse complement, Verified ORF, "Mitotic exit network regulator, forms GTPase-activating Bfa1p-Bub2p complex that binds Tem1p and spindle pole bodies, blocks cell cycle progression before anaphase in response to spindle and kinetochore damage" |
| 4198 | YMR056C | AAC1 SGDID:S000004660, Chr XIII from 388243-387314, reverse complement, Verified ORF, "Mitochondrial inner membrane ADP/ATP translocator, exchanges cytosolic ADP for mitochondrially synthesized ATP; phosphorylated; Aac1p is a minor isoform while Pet9p is the major ADP/ATP translocator" |
| 4199 | YMR058W | FET3 SGDID:S000004662, Chr XIII from 388821-390731, Verified ORF, "Ferro-O2-oxidoreductase required for high-affinity iron uptake and involved in mediating resistance to copper ion toxicity, belongs to class of integral membrane multicopper oxidases" |
| 4200 | YMR059W | SEN15 SGDID:S000004663, Chr XIII from 391098-391484, Verified ORF, "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p" |
| 4201 | YMR060C | SAM37 SGDID:S000004664, Chr XIII from 392514-391531, reverse complement, Verified ORF, "Component of the mitochondrial outer membrane sorting and assembly machinery (SAM) complex; required for the sorting of some proteins to the outer membrane after import by the TOM complex" |
| 4202 | YMR061W | RNA14 SGDID:S000004665, Chr XIII from 392754-394787, Verified ORF, "Cleavage and polyadenylation factor I (CF I) component involved in cleavage and polyadenylation of mRNA 3' ends; bridges interaction between Rna15p and Hrp1p in the CF I complex" |
| 4203 | YMR062C | ECM40 SGDID:S000004666, Chr XIII from 396378-395053, reverse complement, Verified ORF, "Mitochondrial ornithine acetyltransferase, catalyzes the fifth step in arginine biosynthesis; also possesses acetylglutamate synthase activity, regenerates acetylglutamate while forming ornithine" |
| 4204 | YMR063W | RIM9 SGDID:S000004667, Chr XIII from 397076-397795, Verified ORF, "Protein of unknown function, involved in the proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans PalI; putative membrane protein" |
| 4205 | YMR064W | AEP1 SGDID:S000004668, Chr XIII from 397902-399458, Verified ORF, "Protein required for expression of the mitochondrial OLI1 gene encoding subunit 9 of F1-F0 ATP synthase" |
| 4206 | YMR065W | KAR5 SGDID:S000004669, Chr XIII from 399701-401215, Verified ORF, "Protein required for nuclear membrane fusion during karyogamy, localizes to the membrane with a soluble portion in the endoplasmic reticulum lumen, may form a complex with Jem1p and Kar2p; expression of the gene is regulated by pheromone" |
| 4207 | YMR066W | SOV1 SGDID:S000004670, Chr XIII from 401540-404236, Verified ORF, "Mitochondrial protein of unknown function" |
| 4208 | YMR067C | UBX4 SGDID:S000004671, Chr XIII from 405572-404322, reverse complement, Verified ORF, "UBX (ubiquitin regulatory X) domain-containing protein that interacts with Cdc48p" |
| 4209 | YMR068W | AVO2 SGDID:S000004672, Chr XIII from 406303-407583, Verified ORF, "Component of a complex containing the Tor2p kinase and other proteins, which may have a role in regulation of cell growth" |
| 4210 | YMR069W | NAT4 SGDID:S000004673, Chr XIII from 407708-408565, Verified ORF, "N alpha-acetyl-transferase, involved in acetylation of the N-terminal residues of histones H4 and H2A" |
| 4211 | YMR070W | MOT3 SGDID:S000004674, Chr XIII from 409153-410625, Verified ORF, "Nuclear transcription factor with two Cys2-His2 zinc fingers; involved in repression of a subset of hypoxic genes by Rox1p, repression of several DAN/TIR genes during aerobic growth, and repression of ergosterol biosynthetic genes" |
| 4212 | YMR071C | TVP18 SGDID:S000004675, Chr XIII from 411264-410761, reverse complement, Verified ORF, "Integral membrane protein localized to late Golgi vesicles along with the v-SNARE Tlg2p; may interact with ribosomes, based on co-purification experiments" |
| 4213 | YMR072W | ABF2 SGDID:S000004676, Chr XIII from 411568-412119, Verified ORF, "Mitochondrial DNA-binding protein involved in mitochondrial DNA replication and recombination, member of HMG1 DNA-binding protein family; activity may be regulated by protein kinase A phosphorylation" |
| 4214 | YMR073C | IRC21 SGDID:S000004677, Chr XIII from 412872-412267, reverse complement, Verified ORF, "Putative protein of unknown function; proposed to be involved in resistance to carboplatin and cisplatin; shares similarity to a human cytochrome oxidoreductase; null mutant displays increased levels of spontaneous Rad52p foci" |
| 4215 | YMR074C | YMR074C SGDID:S000004678, Chr XIII from 413472-413035, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR074C is not an essential gene" |
| 4216 | YMR075W | RCO1 SGDID:S000004680, Chr XIII from 413981-416035, Verified ORF, "Essential subunit of the histone deacetylase Rpd3S complex; interacts with Eaf3p" |
| 4217 | YMR076C | PDS5 SGDID:S000004681, Chr XIII from 420028-416195, reverse complement, Verified ORF, "Protein required for establishment and maintenance of sister chromatid condensation and cohesion, colocalizes with cohesin on chromosomes in an interdependent manner, may function as a protein-protein interaction scaffold" |
| 4218 | YMR077C | VPS20 SGDID:S000004682, Chr XIII from 422148-421483, reverse complement, Verified ORF, "Myristoylated subunit of ESCRTIII, the endosomal sorting complex required for transport of transmembrane proteins into the multivesicular body pathway to the lysosomal/vacuolar lumen; cytoplasmic protein recruited to endosomal membranes" |
| 4219 | YMR078C | CTF18 SGDID:S000004683, Chr XIII from 424727-422502, reverse complement, Verified ORF, "Subunit of a complex with Ctf8p that shares some subunits with Replication Factor C and is required for sister chromatid cohesion; may have overlapping functions with Rad24p in the DNA damage replication checkpoint" |
| 4220 | YMR079W | SEC14 SGDID:S000004684, Chr XIII from 424988-424996,425153-426058, Verified ORF, "Phosphatidylinositol/phosphatidylcholine transfer protein involved in coordinate regulation of PtdIns and PtdCho metabolism, products of which are regulators in Golgi to plasma membrane transport; functionally homologous to mammalian PITPs" |
| 4221 | YMR080C | NAM7 SGDID:S000004685, Chr XIII from 429626-426711, reverse complement, Verified ORF, "ATP-dependent RNA helicase of the SFI superfamily, required for nonsense mediated mRNA decay and for efficient translation termination at nonsense codons; involved in telomere maintenance" |
| 4222 | YMR081C | ISF1 SGDID:S000004686, Chr XIII from 431094-430078, reverse complement, Verified ORF, "Serine-rich, hydrophilic protein with similarity to Mbr1p; overexpression suppresses growth defects of hap2, hap3, and hap4 mutants; expression is under glucose control; cotranscribed with NAM7 in a cyp1 mutant" |
| 4223 | YMR083W | ADH3 SGDID:S000004688, Chr XIII from 434787-435914, Verified ORF, "Mitochondrial alcohol dehydrogenase isozyme III; involved in the shuttling of mitochondrial NADH to the cytosol under anaerobic conditions and ethanol production" |
| 4224 | YMR084W | YMR084W SGDID:S000004689, Chr XIII from 436627-437415, Uncharacterized ORF, "Putative protein of unknown function; YMR084W and adjacent ORF YMR085W are merged in related strains" |
| 4225 | YMR085W | YMR085W SGDID:S000004690, Chr XIII from 437490-438788, Uncharacterized ORF, "Putative protein of unknown function; YMR085W and adjacent ORF YMR084W are merged in related strains" |
| 4226 | YMR086W | YMR086W SGDID:S000004692, Chr XIII from 439207-442089, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery; cAMP represses YMR086W expression" |
| 4227 | YMR087W | YMR087W SGDID:S000004693, Chr XIII from 442526-443380, Verified ORF, "Putative ADP-ribose-1''-monophosphatase that converts ADP-ribose-1''-monophosphate to ADP-ribose; may have a role in tRNA splicing; contains an A1pp domain" |
| 4228 | YMR088C | VBA1 SGDID:S000004694, Chr XIII from 445101-443413, reverse complement, Verified ORF, "Permease of basic amino acids in the vacuolar membrane" |
| 4229 | YMR089C | YTA12 SGDID:S000004695, Chr XIII from 448085-445608, reverse complement, Verified ORF, "Component, with Afg3p, of the mitochondrial inner membrane m-AAA protease that mediates degradation of misfolded or unassembled proteins and is also required for correct assembly of mitochondrial enzyme complexes" |
| 4230 | YMR090W | YMR090W SGDID:S000004696, Chr XIII from 449244-449927, Uncharacterized ORF, "Putative protein of unknown function with similarity to DTDP-glucose 4,6-dehydratases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YMR090W is not an essential gene" |
| 4231 | YMR091C | NPL6 SGDID:S000004697, Chr XIII from 451364-450057, reverse complement, Verified ORF, "Component of the RSC chromatin remodeling complex; interacts with Rsc3p, Rsc30p, Ldb7p, and Htl1p to form a module important for a broad range of RSC functions; involved in nuclear protein import and maintenance of proper telomere length" |
| 4232 | YMR092C | AIP1 SGDID:S000004698, Chr XIII from 453478-451631, reverse complement, Verified ORF, "Actin cortical patch component, interacts with the actin depolymerizing factor cofilin; required to restrict cofilin localization to cortical patches; contains WD repeats" |
| 4233 | YMR093W | UTP15 SGDID:S000004699, Chr XIII from 454014-455555, Verified ORF, "Nucleolar protein, component of the small subunit (SSU) processome containing the U3 snoRNA that is involved in processing of pre-18S rRNA" |
| 4234 | YMR094W | CTF13 SGDID:S000004700, Chr XIII from 455824-457260, Verified ORF, "Subunit of the CBF3 complex, which binds to the CDE III element of centromeres, bending the DNA upon binding, and may be involved in sister chromatid cohesion during mitosis" |
| 4235 | YMR095C | SNO1 SGDID:S000004701, Chr XIII from 457958-457284, reverse complement, Verified ORF, "Protein of unconfirmed function, involved in pyridoxine metabolism; expression is induced during stationary phase; forms a putative glutamine amidotransferase complex with Snz1p, with Sno1p serving as the glutaminase" |
| 4236 | YMR096W | SNZ1 SGDID:S000004702, Chr XIII from 458407-459300, Verified ORF, "Protein involved in vitamin B6 biosynthesis; member of a stationary phase-induced gene family; coregulated with SNO1; interacts with Sno1p and with Yhr198p, perhaps as a multiprotein complex containing other Snz and Sno proteins" |
| 4237 | YMR097C | MTG1 SGDID:S000004703, Chr XIII from 460526-459423, reverse complement, Verified ORF, "Peripheral GTPase of the mitochondrial inner membrane, essential for respiratory competence, likely functions in assembly of the large ribosomal subunit, has homologs in plants and animals" |
| 4238 | YMR098C | ATP25 SGDID:S000004704, Chr XIII from 462608-460770, reverse complement, Verified ORF, "Mitochondrial protein required for the stability of Oli1p (Atp9p) mRNA and for the Oli1p ring formation; null mutant displays decreased frequency of mitochondrial genome loss (petite formation)" |
| 4239 | YMR099C | YMR099C SGDID:S000004705, Chr XIII from 464826-463933, reverse complement, Verified ORF, "Glucose-6-phosphate 1-epimerase (hexose-6-phosphate mutarotase), likely involved in carbohydrate metabolism; GFP-fusion protein localizes to both the nucleus and cytoplasm and is induced in response to the DNA-damaging agent MMS" |
| 4240 | YMR100W | MUB1 SGDID:S000004706, Chr XIII from 466299-468161, Verified ORF, "Protein of unknown function, deletion causes multi-budding phenotype; has similarity to Aspergillus nidulans samB gene" |
| 4241 | YMR101C | SRT1 SGDID:S000004707, Chr XIII from 469475-468444, reverse complement, Verified ORF, "Cis-prenyltransferase involved in synthesis of long-chain dolichols (19-22 isoprene units; as opposed to Rer2p which synthesizes shorter-chain dolichols); localizes to lipid bodies; transcription is induced during stationary phase" |
| 4242 | YMR102C | YMR102C SGDID:S000004708, Chr XIII from 472351-469847, reverse complement, Uncharacterized ORF, "Protein of unknown function; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance; mutant shows increased resistance to azoles; YMR102C is not an essential gene" |
| 4243 | YMR104C | YPK2 SGDID:S000004710, Chr XIII from 475452-473419, reverse complement, Verified ORF, "Protein kinase with similarityto serine/threonine protein kinase Ypk1p; functionally redundant with YPK1 at the genetic level; participates in a signaling pathway required for optimal cell wall integrity; homolog of mammalian kinase SGK" |
| 4244 | YMR105C | PGM2 SGDID:S000004711, Chr XIII from 477605-475896, reverse complement, Verified ORF, "Phosphoglucomutase, catalyzes the conversion from glucose-1-phosphate to glucose-6-phosphate, which is a key step in hexose metabolism; functions as the acceptor for a Glc-phosphotransferase" |
| 4245 | YMR105W-A | YMR105W-A SGDID:S000028692, Chr XIII from 478063-478257, Uncharacterized ORF, "Putative protein of unknown function" |
| 4246 | YMR106C | YKU80 SGDID:S000004712, Chr XIII from 480189-478300, reverse complement, Verified ORF, "Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair" |
| 4247 | YMR107W | SPG4 SGDID:S000004713, Chr XIII from 483013-483360, Verified ORF, "Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources" |
| 4248 | YMR108W | ILV2 SGDID:S000004714, Chr XIII from 484083-486146, Verified ORF, "Acetolactate synthase, catalyses the first common step in isoleucine and valine biosynthesis and is the target of several classes of inhibitors, localizes to the mitochondria; expression of the gene is under general amino acid control" |
| 4249 | YMR109W | MYO5 SGDID:S000004715, Chr XIII from 486586-490245, Verified ORF, "One of two type I myosins; contains proline-rich tail homology 2 (TH2) and SH3 domains; MYO5 deletion has little effect on growth, but myo3 myo5 double deletion causes severe defects in growth and actin cytoskeleton organization" |
| 4250 | YMR110C | HFD1 SGDID:S000004716, Chr XIII from 491991-490393, reverse complement, Verified ORF, "Putative fatty aldehyde dehydrogenase, located in the mitochondrial outer membrane and also in lipid particles; has similarity to human fatty aldehyde dehydrogenase (FALDH) which is implicated in Sjogren-Larsson syndrome" |
| 4251 | YMR111C | YMR111C SGDID:S000004717, Chr XIII from 493791-492403, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YMR111C is not an essential gene" |
| 4252 | YMR112C | MED11 SGDID:S000004718, Chr XIII from 494494-494099, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential protein" |
| 4253 | YMR113W | FOL3 SGDID:S000004719, Chr XIII from 494998-496281, Verified ORF, "Dihydrofolate synthetase, involved in folic acid biosynthesis; catalyzes the conversion of dihydropteroate to dihydrofolate in folate coenzyme biosynthesis" |
| 4254 | YMR114C | YMR114C SGDID:S000004720, Chr XIII from 497448-496342, reverse complement, Verified ORF, "Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and cytoplasm; YMR114C is not an essential gene" |
| 4255 | YMR115W | FMP24 SGDID:S000004721, Chr XIII from 497703-499208, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 4256 | YMR116C | ASC1 SGDID:S000004722, Chr XIII from 500687-500151,499877-499455, reverse complement, Verified ORF, "G-protein beta subunit and guanine nucleotide dissociation inhibitor for Gpa2p; ortholog of RACK1 that inhibits translation; core component of the small (40S) ribosomal subunit; represses Gcn4p in the absence of amino acid starvation" |
| 4257 | YMR117C | SPC24 SGDID:S000004723, Chr XIII from 501890-501249, reverse complement, Verified ORF, "Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering" |
| 4258 | YMR118C | YMR118C SGDID:S000004724, Chr XIII from 502733-502143, reverse complement, Uncharacterized ORF, "Protein of unknown function with similarity to succinate dehydrogenase cytochrome b subunit; YMR118C is not an essential gene" |
| 4259 | YMR119W | ASI1 SGDID:S000004725, Chr XIII from 505332-507206, Verified ORF, "Putative integral membrane E3 ubiquitin ligase; acts with Asi2p and Asi3p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals" |
| 4260 | YMR120C | ADE17 SGDID:S000004727, Chr XIII from 509279-507501, reverse complement, Verified ORF, "Enzyme of 'de novo' purine biosynthesis containing both 5-aminoimidazole-4-carboxamide ribonucleotide transformylase and inosine monophosphate cyclohydrolase activities, isozyme of Ade16p; ade16 ade17 mutants require adenine and histidine" |
| 4261 | YMR121C | RPL15B SGDID:S000004728, Chr XIII from 510347-509733, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl15Ap and has similarity to rat L15 ribosomal protein; binds to 5.8 S rRNA" |
| 4262 | YMR122W-A | YMR122W-A SGDID:S000007524, Chr XIII from 511314-511568, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and endoplasmic reticulum" |
| 4263 | YMR123W | PKR1 SGDID:S000004730, Chr XIII from 513592-513960, Verified ORF, "V-ATPase assembly factor, functions with other V-ATPase assembly factors in the ER to efficiently assemble the V-ATPase membrane sector (V0); overproduction confers resistance to Pichia farinosa killer toxin" |
| 4264 | YMR124W | YMR124W SGDID:S000004731, Chr XIII from 514455-517286, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck; interacts with Crm1p in two-hybrid assay; YMR124W is not an essential gene" |
| 4265 | YMR125W | STO1 SGDID:S000004732, Chr XIII from 517538-517562,517885-520445, Verified ORF, "Large subunit of the nuclear mRNA cap-binding protein complex, interacts with Npl3p to carry nuclear poly(A)+ mRNA to cytoplasm; also involved in nuclear mRNA degradation and telomere maintenance; orthologous to mammalian CBP80" |
| 4266 | YMR126C | DLT1 SGDID:S000004733, Chr XIII from 521788-520760, reverse complement, Uncharacterized ORF, "Protein of unknown function, mutant sensitive to 6-azauracil (6AU) and mycophenolic acid (MPA)" |
| 4267 | YMR127C | SAS2 SGDID:S000004734, Chr XIII from 523344-522328, reverse complement, Verified ORF, "Histone acetyltransferase (HAT) catalytic subunit of the SAS complex (Sas2p-Sas4p-Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; member of the MYSTacetyltransferase family" |
| 4268 | YMR128W | ECM16 SGDID:S000004735, Chr XIII from 523695-527498, Verified ORF, "Essential DEAH-box ATP-dependent RNA helicase specific to the U3 snoRNP, predominantly nucleolar in distribution, required for 18S rRNA synthesis" |
| 4269 | YMR129W | POM152 SGDID:S000004736, Chr XIII from 527803-531816, Verified ORF, "Nuclear pore membrane glycoprotein; may be involved in duplication of nuclear pores and nuclear pore complexes during S-phase;" |
| 4270 | YMR130W | YMR130W SGDID:S000004737, Chr XIII from 532118-533026, Uncharacterized ORF, "Putative protein of unknown function; YMR130W is not an essential gene" |
| 4271 | YMR131C | RRB1 SGDID:S000004738, Chr XIII from 534697-533162, reverse complement, Verified ORF, "Essential nuclear protein involved in early steps of ribosome biogenesis; physically interacts with the ribosomal protein Rpl3p" |
| 4272 | YMR132C | JLP2 SGDID:S000004739, Chr XIII from 535569-534943, reverse complement, Uncharacterized ORF, "Protein of unknown function, contains sequence that closely resembles a J domain (typified by the E. coli DnaJ protein)" |
| 4273 | YMR133W | REC114 SGDID:S000004740, Chr XIII from 536206-537447,537564-537608, Verified ORF, "Protein involved in early stages of meiotic recombination; possibly involved in the coordination of recombination and meiotic division; mutations lead to premature initiation of the first meiotic division" |
| 4274 | YMR134W | YMR134W SGDID:S000004741, Chr XIII from 537837-538550, Uncharacterized ORF, "Protein that binds to and regulates Erg25p; localized to the ER; null mutant is viable in a respiratory defective background; synthetic lethal with mmt1 and mmt2 mutations; highly conserved in ascomycetes" |
| 4275 | YMR135C | GID8 SGDID:S000004742, Chr XIII from 540055-538688, reverse complement, Verified ORF, "Protein of unknown function, involved in proteasome-dependent catabolite inactivation of fructose-1,6-bisphosphatase; contains LisH and CTLH domains, like Vid30p; dosage-dependent regulator of START" |
| 4276 | YMR136W | GAT2 SGDID:S000004744, Chr XIII from 541198-542880, Verified ORF, "Protein containing GATA family zinc finger motifs; similar to Gln3p and Dal80p; expression repressed by leucine" |
| 4277 | YMR137C | PSO2 SGDID:S000004745, Chr XIII from 544962-542977, reverse complement, Verified ORF, "Required for a post-incision step in the repair of DNA single and double-strand breaks that result from interstrand crosslinks produced by a variety of mono- and bi-functional psoralen derivatives; induced by UV-irradiation" |
| 4278 | YMR138W | CIN4 SGDID:S000004746, Chr XIII from 545154-545729, Verified ORF, "GTP-binding protein involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl; regulated by the GTPase-activating protein, Cin2p, the human retinitis pigmentosa 2 (RP2) homolog" |
| 4279 | YMR139W | RIM11 SGDID:S000004747, Chr XIII from 546124-547236, Verified ORF, "Protein kinase required for signal transduction during entry into meiosis; promotes the formation of the Ime1p-Ume6p complex by phosphorylating Ime1p and Ume6p; shares similarity with mammalian glycogen synthase kinase 3-beta" |
| 4280 | YMR140W | SIP5 SGDID:S000004748, Chr XIII from 547713-549182, Verified ORF, "Protein of unknown function; interacts with both the Reg1p/Glc7p phosphatase and the Snf1p kinase" |
| 4281 | YMR142C | RPL13B SGDID:S000004750, Chr XIII from 551206-551203,550800-550205, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl13Ap; not essential for viability; has similarity to rat L13 ribosomal protein" |
| 4282 | YMR143W | RPS16A SGDID:S000004751, Chr XIII from 551927-551950,552495-552902, Verified ORF, "Protein component of the small (40S) ribosomal subunit; identical to Rps16Bp and has similarity to E. coli S9 and rat S16 ribosomal proteins" |
| 4283 | YMR144W | YMR144W SGDID:S000004752, Chr XIII from 553361-554389, Uncharacterized ORF, "Putative protein of unknown function; localized to the nucleus; YMR144W is not an essential gene" |
| 4284 | YMR145C | NDE1 SGDID:S000004753, Chr XIII from 556474-554792, reverse complement, Verified ORF, "Mitochondrial external NADH dehydrogenase, a type II NAD(P)H:quinone oxidoreductase that catalyzes the oxidation of cytosolic NADH; Nde1p and Nde2p provide cytosolic NADH to the mitochondrial respiratory chain" |
| 4285 | YMR146C | TIF34 SGDID:S000004754, Chr XIII from 558523-557480, reverse complement, Verified ORF, "Subunit of the core complex of translation initiation factor 3(eIF3), which is essential for translation" |
| 4286 | YMR147W | YMR147W SGDID:S000004755, Chr XIII from 559198-559869, Uncharacterized ORF, "Putative protein of unknown function" |
| 4287 | YMR148W | YMR148W SGDID:S000004756, Chr XIII from 560365-560811, Uncharacterized ORF, "Putative protein of unknown function; predicted to contain a transmembrane domain; YMR148W is not an essential gene" |
| 4288 | YMR149W | SWP1 SGDID:S000004757, Chr XIII from 560995-561855, Verified ORF, "Delta subunit of the oligosaccharyl transferase glycoprotein complex, which is required for N-linked glycosylation of proteins in the endoplasmic reticulum" |
| 4289 | YMR150C | IMP1 SGDID:S000004758, Chr XIII from 562527-561955, reverse complement, Verified ORF, "Catalytic subunit of the mitochondrial inner membrane peptidase complex, required for maturation of mitochondrial proteins of the intermembrane space; complex contains Imp1p and Imp2p (both catalytic subunits), and Som1p" |
| 4290 | YMR152W | YIM1 SGDID:S000004760, Chr XIII from 563095-564192, Verified ORF, "Protein of unknown function; null mutant displays sensitivity to DNA damaging agents; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 4291 | YMR153W | NUP53 SGDID:S000004762, Chr XIII from 564434-565861, Verified ORF, "Subunit of the nuclear pore complex (NPC), interacts with karyopherin Kap121p or with Nup170p via overlapping regions of Nup53p, involved in activation of the spindle checkpoint mediated by the Mad1p-Mad2p complex" |
| 4292 | YMR154C | RIM13 SGDID:S000004763, Chr XIII from 568181-565998, reverse complement, Verified ORF, "Calpain-like cysteine protease involved in proteolytic activation of Rim101p in response to alkaline pH; has similarity to A. nidulans palB" |
| 4293 | YMR155W | YMR155W SGDID:S000004764, Chr XIII from 568550-570193, Uncharacterized ORF, "Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen" |
| 4294 | YMR156C | TPP1 SGDID:S000004765, Chr XIII from 571015-570299, reverse complement, Verified ORF, "DNA 3'-phosphatase that functions in repair of endogenous damage of double-stranded DNA, activity is specific for removal of 3' phosphates at strand breaks; has similarity to the l-2-haloacid dehalogenase superfamily" |
| 4295 | YMR157C | YMR157C SGDID:S000004766, Chr XIII from 572043-571276, reverse complement, Uncharacterized ORF, "Protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss and reduced growth rate in minimal glycerol media" |
| 4296 | YMR158C-A | YMR158C-A SGDID:S000007249, Chr XIII from 573330-573193, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, may contain a lipid attachment site; YMR158C-A is not an essential gene" |
| 4297 | YMR158W | MRPS8 SGDID:S000004767, Chr XIII from 572247-572714, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 4298 | YMR159C | ATG16 SGDID:S000004769, Chr XIII from 574927-574475, reverse complement, Verified ORF, "Protein that interacts with the Atg12p-Atg5p conjugate during formation of the pre-autophagosomal structure; essential for autophagy" |
| 4299 | YMR160W | YMR160W SGDID:S000004770, Chr XIII from 575065-577515, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the membrane of the vacuole; mutant has enhanced sensitivity to overexpression of mutant huntingtin; YMR160W is not an essential gene" |
| 4300 | YMR161W | HLJ1 SGDID:S000004771, Chr XIII from 577717-578391, Verified ORF, "Co-chaperone for Hsp40p, anchored in the ER membrane; with its homolog Hdj1p promotes ER-associated protein degradation (ERAD) of integral membrane substrates; similar to E. coli DnaJ" |
| 4301 | YMR162C | DNF3 SGDID:S000004772, Chr XIII from 583920-578950, reverse complement, Verified ORF, "Aminophospholipid translocase (flippase) that maintains membrane lipid asymmetry in post-Golgi secretory vessicles; localizes to the trans-Golgi network; likely involved in protein transport; type 4 P-type ATPase" |
| 4302 | YMR163C | INP2 SGDID:S000004773, Chr XIII from 586387-584270, reverse complement, Verified ORF, "Peroxisome-specific receptor important for peroxisome inheritance; co-fractionates with peroxisome membranes and co-localizes with peroxisomes in vivo; physically interacts with the myosin V motor Myo2p; INP2 is not an essential gene" |
| 4303 | YMR164C | MSS11 SGDID:S000004774, Chr XIII from 589549-587273, reverse complement, Verified ORF, "Transcription factor involved in regulation of invasive growth and starch degradation; controls the activation of MUC1 and STA2 in response to nutritional signals" |
| 4304 | YMR165C | PAH1 SGDID:S000004775, Chr XIII from 592627-590039, reverse complement, Verified ORF, "Mg2+-dependent phosphatidate (PA) phosphatase, catalyzes the dephosphorylation of PA to yield diacylglycerol and Pi, responsible for de novo lipid synthesis; homologous to mammalian lipin 1" |
| 4305 | YMR166C | YMR166C SGDID:S000004776, Chr XIII from 594472-593366, reverse complement, Uncharacterized ORF, "Predicted transporter of the mitochondrial inner membrane; has similarity to human mitochondrial ATP-Mg/Pi carriers; YMR166C is not an essential gene" |
| 4306 | YMR167W | MLH1 SGDID:S000004777, Chr XIII from 594885-597194, Verified ORF, "Protein required for mismatch repair in mitosis and meiosis as well as crossing over during meiosis; forms a complex with Pms1p and Msh2p-Msh3p during mismatch repair; human homolog is associated with hereditary non-polyposis colon cancer" |
| 4307 | YMR168C | CEP3 SGDID:S000004778, Chr XIII from 599157-597331, reverse complement, Verified ORF, "Essential kinetochore protein, component of the CBF3 complex that binds the CDEIII region of the centromere; contains an N-terminal Zn2Cys6 type zinc finger domain, a C-terminal acidic domain, and a putative coiled coil dimerization domain" |
| 4308 | YMR169C | ALD3 SGDID:S000004779, Chr XIII from 600871-599351, reverse complement, Verified ORF, "Cytoplasmic aldehyde dehydrogenase, involved in beta-alanine synthesis; uses NAD+ as the preferred coenzyme; very similar to Ald2p; expression is induced by stress and repressed by glucose" |
| 4309 | YMR170C | ALD2 SGDID:S000004780, Chr XIII from 603081-601561, reverse complement, Verified ORF, "Cytoplasmic aldehyde dehydrogenase, involved in ethanol oxidation and beta-alanine biosynthesis; uses NAD+ as the preferred coenzyme; expression is stress induced and glucose repressed; very similar to Ald3p" |
| 4310 | YMR171C | EAR1 SGDID:S000004781, Chr XIII from 605519-603867, reverse complement, Verified ORF, "Specificity factor required for Rsp5p-dependent ubiquitination and sorting of specific cargo proteins at the multivesicular body; mRNA is targeted to the bud via the mRNA transport system involving She2p: YMR171C is not an essential gene" |
| 4311 | YMR172W | HOT1 SGDID:S000004783, Chr XIII from 605980-608139, Verified ORF, "Transcription factor required for the transient induction of glycerol biosynthetic genes GPD1 and GPP2 in response to high osmolarity; targets Hog1p to osmostress responsive promoters; has similarity to Msn1p and Gcr1p" |
| 4312 | YMR173W | DDR48 SGDID:S000004784, Chr XIII from 608688-609980, Verified ORF, "DNA damage-responsive protein, expression is increased in response to heat-shock stress or treatments that produce DNA lesions; contains multiple repeats of the amino acid sequence NNNDSYGS" |
| 4313 | YMR174C | PAI3 SGDID:S000004786, Chr XIII from 610364-610158, reverse complement, Verified ORF, "Cytoplasmic proteinase A (Pep4p) inhibitor, dependent on Pbs2p and Hog1p protein kinases for osmotic induction; intrinsically unstructured, N-terminal half becomes ordered in the active site of proteinase A upon contact" |
| 4314 | YMR175W | SIP18 SGDID:S000004787, Chr XIII from 611015-611254, Verified ORF, "Protein of unknown function whose expression is induced by osmotic stress" |
| 4315 | YMR175W-A | YMR175W-A SGDID:S000028848, Chr XIII from 611313-611507, Uncharacterized ORF, "Putative protein of unknown function" |
| 4316 | YMR176W | ECM5 SGDID:S000004788, Chr XIII from 611739-615974, Verified ORF, "Non-essential protein of unknown function, contains ATP/GTP-binding site motif A; null mutant exhibits cellular volume up to four times greater than wild-type, also large drooping buds with elongated necks" |
| 4317 | YMR177W | MMT1 SGDID:S000004789, Chr XIII from 616565-618097, Verified ORF, "Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt2p" |
| 4318 | YMR178W | YMR178W SGDID:S000004790, Chr XIII from 618478-619302, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced in response to the DNA-damaging agent MMS; YMR178W is not an essential gene" |
| 4319 | YMR179W | SPT21 SGDID:S000004791, Chr XIII from 619857-622133, Verified ORF, "Protein required for normal transcription at several loci including HTA2-HTB2 and HHF2-HHT2, but not required at the other histone loci; functionally related to Spt10p; involved in telomere maintenance" |
| 4320 | YMR180C | CTL1 SGDID:S000004792, Chr XIII from 623212-622250, reverse complement, Verified ORF, "RNA 5'-triphosphatase, localizes to both the nucleus and cytoplasm" |
| 4321 | YMR181C | YMR181C SGDID:S000004793, Chr XIII from 624079-623615, reverse complement, Uncharacterized ORF, "Protein of unknown function; mRNA transcribed as part of a bicistronic transcript with a predicted transcriptional repressor RGM1/YMR182C; mRNA is destroyed by nonsense-mediated decay (NMD); YMR181C is not an essential gene" |
| 4322 | YMR182C | RGM1 SGDID:S000004794, Chr XIII from 625166-624531, reverse complement, Verified ORF, "Putative transcriptional repressor with proline-rich zinc fingers; overproduction impairs cell growth" |
| 4323 | YMR182W-A | YMR182W-A SGDID:S000028693, Chr XIII from 625810-625896, Uncharacterized ORF, "Putative protein of unknown function" |
| 4324 | YMR183C | SSO2 SGDID:S000004795, Chr XIII from 627807-626920, reverse complement, Verified ORF, "Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane; syntaxin homolog that is functionally redundant with Sso1p" |
| 4325 | YMR184W | ADD37 SGDID:S000004796, Chr XIII from 628188-628784, Verified ORF, "Protein of unknown function involved in ER-associated protein degradation; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS; YMR184W is not an essential gene" |
| 4326 | YMR185W | YMR185W SGDID:S000004797, Chr XIII from 629024-631969, Uncharacterized ORF, "Putative protein of unknown function; essential gene required for viability" |
| 4327 | YMR186W | HSC82 SGDID:S000004798, Chr XIII from 632354-634471, Verified ORF, "Cytoplasmic chaperone of the Hsp90 family, redundant in function and nearly identical with Hsp82p, and together they are essential; expressed constitutively at 10-fold higher basal levels than HSP82 and induced 2-3 fold by heat shock" |
| 4328 | YMR187C | YMR187C SGDID:S000004799, Chr XIII from 635983-634688, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YMR187C is not an essential gene" |
| 4329 | YMR188C | MRPS17 SGDID:S000004800, Chr XIII from 637003-636290, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 4330 | YMR189W | GCV2 SGDID:S000004801, Chr XIII from 637499-640603, Verified ORF, "P subunit of the mitochondrial glycine decarboxylase complex, required for the catabolism of glycine to 5,10-methylene-THF; expression is regulated by levels of 5,10-methylene-THF in the cytoplasm" |
| 4331 | YMR190C | SGS1 SGDID:S000004802, Chr XIII from 645257-640914, reverse complement, Verified ORF, "Nucleolar DNA helicase of the RecQ family involved in maintenance of genome integrity, regulates chromosome synapsis and meiotic crossing over; has similarity to human BLM and WRN helicases implicated in Bloom and Werner syndromes" |
| 4332 | YMR191W | SPG5 SGDID:S000004803, Chr XIII from 645655-646776, Verified ORF, "Protein required for survival at high temperature during stationary phase; not required for growth on nonfermentable carbon sources" |
| 4333 | YMR192W | GYL1 SGDID:S000004804, Chr XIII from 647117-649279, Verified ORF, "Putative GTPase activating protein (GAP) that may have a role in polarized exocytosis; stimulates Gyp5p GAP activity on Ypt1p, colocalizes with Gyp5p at sites of polarized growth; interacts with Gyp5p, Rvs161p, and Rvs167p" |
| 4334 | YMR193W | MRPL24 SGDID:S000004806, Chr XIII from 650035-650811, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 4335 | YMR194C-B | YMR194C-B SGDID:S000028514, Chr XIII from 652886-652847,652774-652593, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 4336 | YMR194W | RPL36A SGDID:S000004807, Chr XIII from 651144-651159,651623-651909, Verified ORF, "N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl36Bp and has similarity to rat L36 ribosomal protein; binds to 5.8 S rRNA" |
| 4337 | YMR195W | ICY1 SGDID:S000004808, Chr XIII from 654033-654416, Verified ORF, "Protein of unknown function, required for viability in rich media of cells lacking mitochondrial DNA; mutants have an invasive growth defect with elongated morphology; induced by amino acid starvation" |
| 4338 | YMR196W | YMR196W SGDID:S000004809, Chr XIII from 655075-658341, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YMR196W is not an essential gene" |
| 4339 | YMR197C | VTI1 SGDID:S000004810, Chr XIII from 659197-658544, reverse complement, Verified ORF, "Protein involved in cis-Golgi membrane traffic; v-SNARE that interacts with two t-SNARES, Sed5p and Pep12p; required for multiple vacuolar sorting pathways" |
| 4340 | YMR198W | CIK1 SGDID:S000004811, Chr XIII from 659744-661528, Verified ORF, "Kinesin-associated protein required for both karyogamy and mitotic spindle organization, interacts stably and specifically with Kar3p and may function to target this kinesin to a specific cellular role; has similarity to Vik1p" |
| 4341 | YMR199W | CLN1 SGDID:S000004812, Chr XIII from 662643-664283, Verified ORF, "G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)" |
| 4342 | YMR200W | ROT1 SGDID:S000004813, Chr XIII from 664751-665521, Verified ORF, "Essential ER membrane protein; may be involved in protein folding; mutation causes defects in cell wall synthesis and in lysis of autophagic bodies, suppresses tor2 mutations, and is synthetically lethal with kar2-1 and with rot2 mutations" |
| 4343 | YMR201C | RAD14 SGDID:S000004814, Chr XIII from 667043-667017,666932-665844, reverse complement, Verified ORF, "Protein that recognizes and binds damaged DNA during nucleotide excision repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); contains zinc finger motif; homolog of human XPA protein" |
| 4344 | YMR202W | ERG2 SGDID:S000004815, Chr XIII from 667536-668204, Verified ORF, "C-8 sterol isomerase, catalyzes the isomerization of the delta-8 double bond to the delta-7 position at an intermediate step in ergosterol biosynthesis" |
| 4345 | YMR203W | TOM40 SGDID:S000004816, Chr XIII from 668491-669654, Verified ORF, "Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; constitutes the core element of the protein conducting pore" |
| 4346 | YMR204C | INP1 SGDID:S000004817, Chr XIII from 671324-670062, reverse complement, Verified ORF, "Peripheral membrane protein of peroxisomes involved in peroxisomal inheritance" |
| 4347 | YMR205C | PFK2 SGDID:S000004818, Chr XIII from 674765-671886, reverse complement, Verified ORF, "Beta subunit of heterooctameric phosphofructokinase involved in glycolysis, indispensable for anaerobic growth, activated by fructose-2,6-bisphosphate and AMP, mutation inhibits glucose induction of cell cycle-related genes" |
| 4348 | YMR206W | YMR206W SGDID:S000004819, Chr XIII from 675895-676836, Uncharacterized ORF, "Putative protein of unknown function; YMR206W is not an essential gene" |
| 4349 | YMR207C | HFA1 SGDID:S000004820, Chr XIII from 683563-677192, reverse complement, Verified ORF, "Mitochondrial acetyl-coenzyme A carboxylase, catalyzes the production of malonyl-CoA in mitochondrial fatty acid biosynthesis" |
| 4350 | YMR208W | ERG12 SGDID:S000004821, Chr XIII from 684466-685797, Verified ORF, "Mevalonate kinase, acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate" |
| 4351 | YMR209C | YMR209C SGDID:S000004822, Chr XIII from 687283-685910, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YMR209C is not an essential gene" |
| 4352 | YMR210W | YMR210W SGDID:S000004823, Chr XIII from 687515-688864, Verified ORF, "Putative acyltransferase with similarity to Eeb1p and Eht1p, has a minor role in medium-chain fatty acid ethyl ester biosynthesis; may be involved in lipid metabolism and detoxification" |
| 4353 | YMR211W | DML1 SGDID:S000004824, Chr XIII from 689082-690509, Verified ORF, "Essential protein involved in mtDNA inheritance, may also function in the partitioning of the mitochondrial organelle or in the segregation of chromosomes, exhibits regions similar to members of a GTPase family" |
| 4354 | YMR212C | EFR3 SGDID:S000004825, Chr XIII from 693042-690694, reverse complement, Verified ORF, "Non-essential protein of unknown function; exhibits synthetic lethal genetic interactions with PHO85; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies and is phosphorylated" |
| 4355 | YMR213W | CEF1 SGDID:S000004826, Chr XIII from 693380-695152, Verified ORF, "Essential splicing factor; associated with Prp19p and the spliceosome, contains an N-terminal c-Myb DNA binding motif necessary for cell viability but not for Prp19p association, evolutionarily conserved and homologous to S. pombe Cdc5p" |
| 4356 | YMR214W | SCJ1 SGDID:S000004827, Chr XIII from 695349-696482, Verified ORF, "One of several homologs of bacterial chaperone DnaJ, located in the ER lumen where it cooperates with Kar2p to mediate maturation of proteins" |
| 4357 | YMR215W | GAS3 SGDID:S000004828, Chr XIII from 696795-698369, Verified ORF, "Putative 1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall" |
| 4358 | YMR216C | SKY1 SGDID:S000004829, Chr XIII from 701038-698810, reverse complement, Verified ORF, "SR protein kinase (SRPK) involved in regulating proteins involved in mRNA metabolism and cation homeostasis; similar to human SRPK1" |
| 4359 | YMR217W | GUA1 SGDID:S000004830, Chr XIII from 701789-703366, Verified ORF, "GMP synthase, an enzyme that catalyzes the second step in the biosynthesis of GMP from inosine 5'-phosphate (IMP); transcription is not subject to regulation by guanine but is negatively regulated by nutrient starvation" |
| 4360 | YMR218C | TRS130 SGDID:S000004831, Chr XIII from 706886-703578, reverse complement, Verified ORF, "One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in ER to Golgi membrane traffic; mutation activates transcription of OCH1" |
| 4361 | YMR219W | ESC1 SGDID:S000004832, Chr XIII from 707132-712108, Verified ORF, "Protein localized to the nuclear periphery, involved in telomeric silencing; interacts with PAD4-domain of Sir4p" |
| 4362 | YMR220W | ERG8 SGDID:S000004833, Chr XIII from 712315-713670, Verified ORF, "Phosphomevalonate kinase, an essential cytosolic enzyme that acts in the biosynthesis of isoprenoids and sterols, including ergosterol, from mevalonate" |
| 4363 | YMR221C | YMR221C SGDID:S000004834, Chr XIII from 715444-713930, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; physical interaction with Atg27p suggests a possible role in autophagy" |
| 4364 | YMR222C | FSH2 SGDID:S000004835, Chr XIII from 716308-715637, reverse complement, Verified ORF, "Serine hydrolase that localizes to the cytoplasm; sequence is similar to Fsh1p and Fsh3p" |
| 4365 | YMR223W | UBP8 SGDID:S000004836, Chr XIII from 716714-718129, Verified ORF, "Ubiquitin-specific protease that is a component of the SAGA (Spt-Ada-Gcn5-Acetyltransferase) acetylation complex; required for SAGA-mediated deubiquitination of histone H2B" |
| 4366 | YMR224C | MRE11 SGDID:S000004837, Chr XIII from 720652-718574, reverse complement, Verified ORF, "Subunit of a complex with Rad50p and Xrs2p (MRX complex) that functions in repair of DNA double-strand breaks and in telomere stability, exhibits nuclease activity that appears to be required for MRX function; widely conserved" |
| 4367 | YMR225C | MRPL44 SGDID:S000004838, Chr XIII from 721402-721345,721197-720959, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 4368 | YMR226C | YMR226C SGDID:S000004839, Chr XIII from 722395-721592, reverse complement, Verified ORF, "NADP(+)-dependent dehydrogenase; acts on serine, L-allo-threonine, and other 3-hydroxy acids; green fluorescent protein fusion protein localizes to the cytoplasm and nucleus; may interact with ribosomes, based on co-purification experiments" |
| 4369 | YMR227C | TAF7 SGDID:S000004840, Chr XIII from 724384-722612, reverse complement, Verified ORF, "TFIID subunit (67 kDa), involved in RNA polymerase II transcription initiation" |
| 4370 | YMR228W | MTF1 SGDID:S000004841, Chr XIII from 724625-725650, Verified ORF, "Mitochondrial RNA polymerase specificity factor with structural similarity to S-adenosylmethionine-dependent methyltransferases and functional similarity to bacterial sigma-factors, interacts with mitochondrial core polymerase Rpo41p" |
| 4371 | YMR229C | RRP5 SGDID:S000004842, Chr XIII from 731122-725933, reverse complement, Verified ORF, "RNA binding protein with preference for single stranded tracts of U's involved in synthesis of both 18S and 5.8S rRNAs; component of both the ribosomal small subunit (SSU) processosome and the 90S preribosome" |
| 4372 | YMR230W | RPS10B SGDID:S000004843, Chr XIII from 732413-732464,732875-733140, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps10Ap and has similarity to rat ribosomal protein S10" |
| 4373 | YMR230W-A | YMR230W-A SGDID:S000028576, Chr XIII from 733267-733455, Uncharacterized ORF, "Putative protein of unknown function" |
| 4374 | YMR231W | PEP5 SGDID:S000004844, Chr XIII from 733544-736633, Verified ORF, "Component of CORVET tethering complex; peripheral vacuolar membrane protein required for protein trafficking and vacuole biogenesis; interacts with Pep7p" |
| 4375 | YMR232W | FUS2 SGDID:S000004845, Chr XIII from 736925-738958, Verified ORF, "Cytoplasmic protein localized to the shmoo tip; required for the alignment of parental nuclei before nuclear fusion during mating" |
| 4376 | YMR233W | TRI1 SGDID:S000004846, Chr XIII from 739184-739864, Verified ORF, "Non-essential sumoylated protein of unknown function with similarity to components of human SWI/SNF complex including SMRD3; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm, nucleus and nucleolus" |
| 4377 | YMR234W | RNH1 SGDID:S000004847, Chr XIII from 740265-741311, Verified ORF, "Ribonuclease H1; able to bind double-stranded RNAs and RNA-DNA hybrids; associates with RNAse polymerase I; the homolog of mammalian RNAse HII (the S. cerevisiae homolog of mammalian RNAse HI is RNH201)" |
| 4378 | YMR235C | RNA1 SGDID:S000004848, Chr XIII from 742734-741511, reverse complement, Verified ORF, "GTPase activating protein (GAP) for Gsp1p, involved in nuclear transport" |
| 4379 | YMR236W | TAF9 SGDID:S000004849, Chr XIII from 742970-743443, Verified ORF, "Subunit (17 kDa) of TFIID and SAGA complexes, involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H3" |
| 4380 | YMR237W | BCH1 SGDID:S000004850, Chr XIII from 743748-745922, Verified ORF, "Member of the ChAPs family (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms the exomer complex with Chs5p to mediate export of specific cargo proteins from the Golgi to the plasma membrane; may interact with ribosomes" |
| 4381 | YMR238W | DFG5 SGDID:S000004851, Chr XIII from 746352-747728, Verified ORF, "Putative mannosidase, essential glycosylphosphatidylinositol (GPI)-anchored membrane protein required for cell wall biogenesis in bud formation, involved in filamentous growth, homologous to Dcw1p" |
| 4382 | YMR239C | RNT1 SGDID:S000004852, Chr XIII from 749676-748261, reverse complement, Verified ORF, "RNAase III; involved in rDNA transcription and rRNA processing; also cleaves a stem-loop structure at the 3' end of U2 snRNA to ensure formation of the correct U2 3' end" |
| 4383 | YMR240C | CUS1 SGDID:S000004853, Chr XIII from 751239-749929, reverse complement, Verified ORF, "Protein required for assembly of U2 snRNP into the spliceosome, forms a complex with Hsh49p and Hsh155p" |
| 4384 | YMR241W | YHM2 SGDID:S000004854, Chr XIII from 751960-752904, Verified ORF, "Mitochondrial DNA-binding protein, component of the mitochondrial nucleoid structure, involved in mtDNA replication and segregation of mitochondrial genomes; member of the mitochondrial carrier protein family" |
| 4385 | YMR242C | RPL20A SGDID:S000004855, Chr XIII from 754219-754219,753741-753224, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Bp and has similarity to rat L18a ribosomal protein" |
| 4386 | YMR242W-A | YMR242W-A SGDID:S000028694, Chr XIII from 754296-754385, Uncharacterized ORF, "Putative protein of unknown function" |
| 4387 | YMR243C | ZRC1 SGDID:S000004856, Chr XIII from 756165-754837, reverse complement, Verified ORF, "Vacuolar membrane zinc transporter, transports zinc from the cytosol into the vacuole for storage; also has a role in resistance to zinc shock resulting from a sudden influx of zinc into the cytoplasm" |
| 4388 | YMR244C-A | YMR244C-A SGDID:S000004857, Chr XIII from 758830-758516, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced in response to the DNA-damaging agent MMS; YMR244C-A is not an essential gene" |
| 4389 | YMR244W | YMR244W SGDID:S000004858, Chr XIII from 757249-758316, Uncharacterized ORF, "Putative protein of unknown function" |
| 4390 | YMR246W | FAA4 SGDID:S000004860, Chr XIII from 759806-761890, Verified ORF, "Long chain fatty acyl-CoA synthetase, regulates protein modification during growth in the presence of ethanol, functions to incorporate palmitic acid into phospholipids and neutral lipids" |
| 4391 | YMR247C | RKR1 SGDID:S000004861, Chr XIII from 768038-763350, reverse complement, Verified ORF, "Nuclear RING domain protein with functional connections to chromatin modification; may interact with ribosomes, based on co-purification experiments; YMR247C is not an essential gene" |
| 4392 | YMR247W-A | YMR247W-A SGDID:S000028849, Chr XIII from 769282-769425, Uncharacterized ORF, "Putative protein of unknown function" |
| 4393 | YMR250W | GAD1 SGDID:S000004862, Chr XIII from 770800-772557, Verified ORF, "Glutamate decarboxylase, converts glutamate into gamma-aminobutyric acid (GABA) during glutamate catabolism; involved in response to oxidative stress" |
| 4394 | YMR251W | GTO3 SGDID:S000004863, Chr XIII from 772914-774014, Verified ORF, "Omega class glutathione transferase; putative cytosolic localization" |
| 4395 | YMR251W-A | HOR7 SGDID:S000004864, Chr XIII from 774751-774930, Verified ORF, "Protein of unknown function; overexpression suppresses Ca2+ sensitivity of mutants lacking inositol phosphorylceramide mannosyltransferases Csg1p and Csh1p; transcription is induced under hyperosmotic stress and repressed by alpha factor" |
| 4396 | YMR252C | YMR252C SGDID:S000004865, Chr XIII from 775718-775314, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YMR252C is not an essential gene" |
| 4397 | YMR253C | YMR253C SGDID:S000004866, Chr XIII from 777189-775945, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern; YMR253C is not an essential gene" |
| 4398 | YMR255W | GFD1 SGDID:S000004868, Chr XIII from 778000-778566, Verified ORF, "Coiled-coiled protein of unknown function, identified as a high-copy suppressor of a dbp5 mutation" |
| 4399 | YMR256C | COX7 SGDID:S000004869, Chr XIII from 779126-778944, reverse complement, Verified ORF, "Subunit VII of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain" |
| 4400 | YMR257C | PET111 SGDID:S000004870, Chr XIII from 782030-779628, reverse complement, Verified ORF, "Mitochondrial translational activator specific for the COX2 mRNA; located in the mitochondrial inner membrane" |
| 4401 | YMR258C | YMR258C SGDID:S000004871, Chr XIII from 784280-782619, reverse complement, Uncharacterized ORF, "Protein of unknown function with similarity to F-box proteins; physically interacts with Skp1p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YMR258C is not an essential gene" |
| 4402 | YMR259C | YMR259C SGDID:S000004872, Chr XIII from 788882-784620, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YMR259C is not an essential gene" |
| 4403 | YMR260C | TIF11 SGDID:S000004873, Chr XIII from 789838-789377, reverse complement, Verified ORF, "Translation initiation factor eIF1A, essential protein that forms a complex with Sui1p (eIF1) and the 40S ribosomal subunit and scans for the start codon; C-terminus associates with Fun12p (eIF5B); N terminus interacts with eIF2 and eIF3" |
| 4404 | YMR261C | TPS3 SGDID:S000004874, Chr XIII from 793368-790204, reverse complement, Verified ORF, "Regulatory subunit of trehalose-6-phosphate synthase/phosphatase complex, which synthesizes the storage carbohydrate trehalose; expression is induced by stress conditions and repressed by the Ras-cAMP pathway" |
| 4405 | YMR262W | YMR262W SGDID:S000004875, Chr XIII from 793725-794666, Uncharacterized ORF, "Protein of unknown function; interacts weakly with Knr4p; YMR262W is not an essential gene" |
| 4406 | YMR263W | SAP30 SGDID:S000004876, Chr XIII from 794918-795523, Verified ORF, "Subunit of a histone deacetylase complex, along with Rpd3p and Sin3p, that is involved in silencing at telomeres, rDNA, and silent mating-type loci; involved in telomere maintenance" |
| 4407 | YMR264W | CUE1 SGDID:S000004877, Chr XIII from 795804-796415, Verified ORF, "Endoplasmic reticulum membrane protein that recruits the ubiquitin-conjugating enzyme Ubc7p to the ER where it functions in protein degradation; contains a CUE domain that binds ubiquitin to facilitate intramolecular monoubiquitination" |
| 4408 | YMR265C | YMR265C SGDID:S000004878, Chr XIII from 797924-796539, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 4409 | YMR266W | RSN1 SGDID:S000004879, Chr XIII from 798517-801378, Verified ORF, "Membrane protein of unknown function; overexpression suppresses NaCl sensitivity of sro7 mutant" |
| 4410 | YMR267W | PPA2 SGDID:S000004880, Chr XIII from 801771-802703, Verified ORF, "Mitochondrial inorganic pyrophosphatase, required for mitochondrial function and possibly involved in energy generation from inorganic pyrophosphate" |
| 4411 | YMR268C | PRP24 SGDID:S000004881, Chr XIII from 804221-802887, reverse complement, Verified ORF, "Splicing factor that reanneals U4 and U6 snRNPs during spliceosome recycling" |
| 4412 | YMR269W | TMA23 SGDID:S000004882, Chr XIII from 804455-805090, Verified ORF, "Nucleolar protein of unknown function implicated in ribosome biogenesis; TMA23 may be a fungal-specific gene as no homologs have been yet identified in higher eukaryotes" |
| 4413 | YMR270C | RRN9 SGDID:S000004883, Chr XIII from 806422-805325, reverse complement, Verified ORF, "Protein involved in promoting high level transcription of rDNA, subunit of UAF (upstream activation factor) for RNA polymerase I" |
| 4414 | YMR271C | URA10 SGDID:S000004884, Chr XIII from 807547-806864, reverse complement, Verified ORF, "Minor orotate phosphoribosyltransferase (OPRTase) isozyme that catalyzes the fifth enzymatic step in the de novo biosynthesis of pyrimidines, converting orotate into orotidine-5'-phosphate; major OPRTase encoded by URA5" |
| 4415 | YMR272C | SCS7 SGDID:S000004885, Chr XIII from 810776-809622, reverse complement, Verified ORF, "Sphingolipid alpha-hydroxylase, functions in the alpha-hydroxylation of sphingolipid-associated very long chain fatty acids, has both cytochrome b5-like and hydroxylase/desaturase domains, not essential for growth" |
| 4416 | YMR272W-B | YMR272W-B SGDID:S000028696, Chr XIII from 811088-811195, Uncharacterized ORF, "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 4417 | YMR273C | ZDS1 SGDID:S000004886, Chr XIII from 813979-811232, reverse complement, Verified ORF, "Protein that interacts with silencing proteins at the telomere, involved in transcriptional silencing; has a role in localization of Bcy1p, a regulatory subunit of protein kinase A; implicated in mRNA nuclear export" |
| 4418 | YMR274C | RCE1 SGDID:S000004887, Chr XIII from 815310-814363, reverse complement, Verified ORF, "Type II CAAX prenyl protease involved in the proteolysis and maturation of Ras and the a-factor mating pheromone" |
| 4419 | YMR275C | BUL1 SGDID:S000004888, Chr XIII from 818580-815650, reverse complement, Verified ORF, "Ubiquitin-binding component of the Rsp5p E3-ubiquitin ligase complex, functional homolog of Bul2p, disruption causes temperature-sensitive growth, overexpression causes missorting of amino acid permeases" |
| 4420 | YMR276W | DSK2 SGDID:S000004889, Chr XIII from 818826-819947, Verified ORF, "Nuclear-enriched ubiquitin-like polyubiquitin-binding protein, required for spindle pole body (SPB) duplication and for transit through the G2/M phase of the cell cycle, involved in proteolysis, interacts with the proteasome" |
| 4421 | YMR277W | FCP1 SGDID:S000004890, Chr XIII from 820255-822453, Verified ORF, "Carboxy-terminal domain (CTD) phosphatase, essential for dephosphorylation of the repeated C-terminal domain of the RNA polymerase II large subunit (Rpo21p)" |
| 4422 | YMR278W | PGM3 SGDID:S000004891, Chr XIII from 822762-824630, Verified ORF, "Phosphoglucomutase, catalyzes interconversion of glucose-1-phosphate and glucose-6-phospate; transcription induced in response to stress; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; non-essential" |
| 4423 | YMR279C | YMR279C SGDID:S000004892, Chr XIII from 826350-824728, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified as a heat-induced gene in a high-throughout screen; YMR279C is not an essential gene" |
| 4424 | YMR280C | CAT8 SGDID:S000004893, Chr XIII from 831328-827027, reverse complement, Verified ORF, "Zinc cluster transcriptional activator necessary for derepression of a variety of genes under non-fermentative growth conditions, active after diauxic shift, binds carbon source responsive elements" |
| 4425 | YMR281W | GPI12 SGDID:S000004894, Chr XIII from 832338-833252, Verified ORF, "ER membrane protein involved in the second step of glycosylphosphatidylinositol (GPI) anchor assembly, the de-N-acetylation of the N-acetylglucosaminylphosphatidylinositol intermediate; functional homolog of human PIG-Lp" |
| 4426 | YMR282C | AEP2 SGDID:S000004895, Chr XIII from 835097-833355, reverse complement, Verified ORF, "Mitochondrial protein, likely involved in translation of the mitochondrial OLI1 mRNA; exhibits genetic interaction with the OLI1 mRNA 5'-untranslated leader" |
| 4427 | YMR283C | RIT1 SGDID:S000004896, Chr XIII from 836866-835325, reverse complement, Verified ORF, "2'-O-ribosyl phosphate transferase, modifies the initiator methionine tRNA at position 64 to distinguish it from elongator methionine tRNA" |
| 4428 | YMR284W | YKU70 SGDID:S000004897, Chr XIII from 838186-839994, Verified ORF, "Subunit of the telomeric Ku complex (Yku70p-Yku80p), involved in telomere length maintenance, structure and telomere position effect; relocates to sites of double-strand cleavage to promote nonhomologous end joining during DSB repair" |
| 4429 | YMR285C | NGL2 SGDID:S000004898, Chr XIII from 841690-840143, reverse complement, Verified ORF, "Protein involved in 5.8S rRNA processing; Ccr4p-like RNase required for correct 3'-end formation of 5.8S rRNA at site E; similar to Ngl1p and Ngl3p" |
| 4430 | YMR286W | MRPL33 SGDID:S000004899, Chr XIII from 841941-842201, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 4431 | YMR287C | DSS1 SGDID:S000004900, Chr XIII from 845344-842435, reverse complement, Verified ORF, "3'-5' exoribonuclease, component of the mitochondrial degradosome along with the ATP-dependent RNA helicase Suv3p; the degradosome associates with the ribosome and mediates turnover of aberrant or unprocessed RNAs" |
| 4432 | YMR288W | HSH155 SGDID:S000004901, Chr XIII from 845570-848485, Verified ORF, "U2-snRNP associated splicing factor that forms extensive associations with the branch site-3' splice site-3' exon region upon prespliceosome formation; similarity to the mammalian U2 snRNP-associated splicing factor SAP155" |
| 4433 | YMR289W | ABZ2 SGDID:S000004902, Chr XIII from 848684-849808, Verified ORF, "Aminodeoxychorismate lyase (4-amino-4-deoxychorismate lyase), catalyzes the third step in para-aminobenzoic acid biosynthesis; involved in folic acid biosynthesis" |
| 4434 | YMR290C | HAS1 SGDID:S000004903, Chr XIII from 851590-850073, reverse complement, Verified ORF, "ATP-dependent RNA helicase; localizes to both the nuclear periphery and nucleolus; highly enriched in nuclear pore complex fractions; constituent of 66S pre-ribosomal particles" |
| 4435 | YMR291W | YMR291W SGDID:S000004905, Chr XIII from 852629-854389, Uncharacterized ORF, "Putative kinase of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YMR291W is not an essential gene" |
| 4436 | YMR292W | GOT1 SGDID:S000004906, Chr XIII from 854794-854815,854898-855292, Verified ORF, "Evolutionarily conserved non-essential protein present in early Golgi cisternae that may be involved in ER-Golgi transport at a step after vesicle tethering to Golgi membranes, exhibits membrane topology similar to that of Sft2p" |
| 4437 | YMR293C | YMR293C SGDID:S000004907, Chr XIII from 856792-855398, reverse complement, Uncharacterized ORF, "Putative protein similar to bacterial glutamyl-tRNA amidotransferases; non-tagged protein is detected in purified mitochondria; null mutant displays decreased frequency of mitochondrial genome loss (petite formation)" |
| 4438 | YMR294W | JNM1 SGDID:S000004908, Chr XIII from 856965-858086, Verified ORF, "Component of the yeast dynactin complex, consisting of Nip100p, Jnm1p, and Arp1p; required for proper nuclear migration and spindle partitioning during mitotic anaphase B" |
| 4439 | YMR295C | YMR295C SGDID:S000004910, Chr XIII from 858889-858296, reverse complement, Verified ORF, "Protein of unknown function that associates with ribosomes; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and bud; YMR295C is not an essential gene" |
| 4440 | YMR296C | LCB1 SGDID:S000004911, Chr XIII from 860890-859214, reverse complement, Verified ORF, "Component of serine palmitoyltransferase, responsible along with Lcb2p for the first committed step in sphingolipid synthesis, which is the condensation of serine with palmitoyl-CoA to form 3-ketosphinganine" |
| 4441 | YMR297W | PRC1 SGDID:S000004912, Chr XIII from 861921-863519, Verified ORF, "Vacuolar carboxypeptidase Y (proteinase C), broad-specificity C-terminal exopeptidase involved in non-specific protein degradation in the vacuole; member of the serine carboxypeptidase family" |
| 4442 | YMR298W | LIP1 SGDID:S000004913, Chr XIII from 863818-864270, Verified ORF, "Ceramide synthase subunit; single-span ER membrane protein associated with Lag1p and Lac1p and required for ceramide synthase activity, null mutant grows extremely slowly and is defective in ceramide synthesis" |
| 4443 | YMR299C | DYN3 SGDID:S000004914, Chr XIII from 865349-864411, reverse complement, Verified ORF, "Dynein light intermediate chain (LIC); localizes with dynein, null mutant is defective in nuclear migration" |
| 4444 | YMR300C | ADE4 SGDID:S000004915, Chr XIII from 867090-865558, reverse complement, Verified ORF, "Phosphoribosylpyrophosphate amidotransferase (PRPPAT; amidophosphoribosyltransferase), catalyzes first step of the 'de novo' purine nucleotide biosynthetic pathway" |
| 4445 | YMR301C | ATM1 SGDID:S000004916, Chr XIII from 869626-867554, reverse complement, Verified ORF, "Mitochondrial inner membrane ATP-binding cassette (ABC) transporter, exports mitochondrially synthesized precursors of iron-sulfur (Fe/S) clusters to the cytosol" |
| 4446 | YMR302C | YME2 SGDID:S000004917, Chr XIII from 872624-870072, reverse complement, Verified ORF, "Integral inner mitochondrial membrane protein with a role in maintaining mitochondrial nucleoid structure and number; mutants exhibit an increased rate of mitochondrial DNA escape; shows some sequence similarity to exonucleases" |
| 4447 | YMR303C | ADH2 SGDID:S000004918, Chr XIII from 874336-873290, reverse complement, Verified ORF, "Glucose-repressible alcohol dehydrogenase II, catalyzes the conversion of ethanol to acetaldehyde; involved in the production of certain carboxylate esters; regulated by ADR1" |
| 4448 | YMR304W | UBP15 SGDID:S000004920, Chr XIII from 874986-878678, Verified ORF, "Ubiquitin-specific protease that may play a role in ubiquitin precursor processing" |
| 4449 | YMR305C | SCW10 SGDID:S000004921, Chr XIII from 880231-879062, reverse complement, Verified ORF, "Cell wall protein with similarity to glucanases; may play a role in conjugation during mating based on mutant phenotype and its regulation by Ste12p" |
| 4450 | YMR306W | FKS3 SGDID:S000004923, Chr XIII from 881158-886515, Verified ORF, "Protein involved in spore wall assembly, has similarity to 1,3-beta-D-glucan synthase catalytic subunits Fks1p and Gsc2p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 4451 | YMR307W | GAS1 SGDID:S000004924, Chr XIII from 887002-888681, Verified ORF, "Beta-1,3-glucanosyltransferase, required for cell wall assembly; localizes to the cell surface via a glycosylphosphatidylinositol (GPI) anchor" |
| 4452 | YMR308C | PSE1 SGDID:S000004925, Chr XIII from 892220-888951, reverse complement, Verified ORF, "Karyopherin/importin that interacts with the nuclear pore complex; acts as the nuclear import receptor for specific proteins, including Pdr1p, Yap1p, Ste12p, and Aft1p" |
| 4453 | YMR309C | NIP1 SGDID:S000004926, Chr XIII from 895425-892987, reverse complement, Verified ORF, "Subunit of the eukaryotic translation initiation factor 3 (eIF3), involved in the assembly of preinitiation complex and start codon selection" |
| 4454 | YMR310C | YMR310C SGDID:S000004927, Chr XIII from 896668-895715, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YMR310C is not an essential gene" |
| 4455 | YMR311C | GLC8 SGDID:S000004928, Chr XIII from 897602-896913, reverse complement, Verified ORF, "Regulatory subunit of protein phosphatase 1 (Glc7p), involved in glycogen metabolism and chromosome segregation; proposed to regulate Glc7p activity via conformational alteration; ortholog of the mammalian protein phosphatase inhibitor 2" |
| 4456 | YMR312W | ELP6 SGDID:S000004929, Chr XIII from 898404-899225, Verified ORF, "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity" |
| 4457 | YMR313C | TGL3 SGDID:S000004930, Chr XIII from 901306-899378, reverse complement, Verified ORF, "Triacylglycerol lipase of the lipid particle, responsible for all the TAG lipase activity of the lipid particle; contains the consensus sequence motif GXSXG, which is found in lipolytic enzymes" |
| 4458 | YMR314W | PRE5 SGDID:S000004931, Chr XIII from 901708-902412, Verified ORF, "Alpha 6 subunit of the 20S proteasome" |
| 4459 | YMR315W | YMR315W SGDID:S000004932, Chr XIII from 902799-903848, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YMR315W is not an essential gene" |
| 4460 | YMR315W-A | YMR315W-A SGDID:S000028697, Chr XIII from 904285-904392, Uncharacterized ORF, "Putative protein of unknown function" |
| 4461 | YMR316W | DIA1 SGDID:S000004935, Chr XIII from 904823-905833, Verified ORF, "Protein of unknown function, involved in invasive and pseudohyphal growth; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 4462 | YMR317W | YMR317W SGDID:S000004936, Chr XIII from 907362-910784, Uncharacterized ORF, "Putative protein of unknown function with some similarity to sialidase from Trypanosoma; YMR317W is not an essential gene" |
| 4463 | YMR318C | ADH6 SGDID:S000004937, Chr XIII from 912141-911059, reverse complement, Verified ORF, "NADPH-dependent medium chain alcohol dehydrogenase with broad substrate specificity; member of the cinnamyl family of alcohol dehydrogenases; may be involved in fusel alcohol synthesis or in aldehyde tolerance" |
| 4464 | YMR319C | FET4 SGDID:S000004938, Chr XIII from 914536-912878, reverse complement, Verified ORF, "Low-affinity Fe(II) transporter of the plasma membrane" |
| 4465 | YMR321C | YMR321C SGDID:S000004940, Chr XIII from 917894-917577, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 4466 | YMR322C | SNO4 SGDID:S000004941, Chr XIII from 919077-918364, reverse complement, Uncharacterized ORF, "Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp32p, and Hsp33p; member of the DJ-1/ThiJ/PfpI superfamily; may have a role in pyridoxine metabolism" |
| 4467 | YMR323W | ERR3 SGDID:S000004942, Chr XIII from 920086-921399, Verified ORF, "Protein of unknown function, has similarity to enolases" |
| 4468 | YMR325W | YMR325W SGDID:S000004944, Chr XIII from 922639-923013, Uncharacterized ORF, "Hypothetical protein" |
| 4469 | YNL001W | DOM34 SGDID:S000004946, Chr XIV from 627458-628618, Verified ORF, "Endoribonuclease; functions in no-go mRNA decay, protein translation to promote G1 progression and differentiation, required for meiotic cell division; similar to the eukaryotic Pelota" |
| 4470 | YNL002C | RLP7 SGDID:S000004947, Chr XIV from 627144-626176, reverse complement, Verified ORF, "Nucleolar protein with similarity to large ribosomal subunit L7 proteins; constituent of 66S pre-ribosomal particles; plays an essential role in processing of precursors to the large ribosomal subunit RNAs" |
| 4471 | YNL003C | PET8 SGDID:S000004948, Chr XIV from 625831-624977, reverse complement, Verified ORF, "S-adenosylmethionine transporter of the mitochondrial inner membrane, member of the mitochondrial carrier family; required for biotin biosynthesis and respiratory growth" |
| 4472 | YNL004W | HRB1 SGDID:S000004949, Chr XIV from 622917-622946,623289-624623, Verified ORF, "Poly(A+) RNA-binding protein, involved in the export of mRNAs from the nucleus to the cytoplasm; similar to Gbp2p and Npl3p" |
| 4473 | YNL005C | MRP7 SGDID:S000004950, Chr XIV from 622430-621315, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 4474 | YNL006W | LST8 SGDID:S000004951, Chr XIV from 620069-620980, Verified ORF, "Protein required for the transport of amino acid permease Gap1p from the Golgi to the cell surface; component of the TOR signaling pathway; associates with both Tor1p and Tor2p; contains a WD-repeat" |
| 4475 | YNL007C | SIS1 SGDID:S000004952, Chr XIV from 619567-618509, reverse complement, Verified ORF, "Type II HSP40 co-chaperone that interacts with the HSP70 protein Ssa1p; not functionally redundant with Ydj1p due to due to substrate specificity; shares similarity with bacterial DnaJ proteins" |
| 4476 | YNL008C | ASI3 SGDID:S000004953, Chr XIV from 618221-616212, reverse complement, Verified ORF, "Putative integral membrane E3 ubiquitin ligase; acts with Asi1p and Asi2p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals" |
| 4477 | YNL009W | IDP3 SGDID:S000004954, Chr XIV from 614822-616084, Verified ORF, "Peroxisomal NADP-dependent isocitrate dehydrogenase, catalyzes oxidation of isocitrate to alpha-ketoglutarate with the formation of NADP(H+), required for growth on unsaturated fatty acids" |
| 4478 | YNL010W | YNL010W SGDID:S000004955, Chr XIV from 613636-614361, Uncharacterized ORF, "Putative protein of unknown function with similarity to phosphoserine phosphatases; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; homozygous diploid mutant shows an increase in glycogen accumulation" |
| 4479 | YNL011C | YNL011C SGDID:S000004956, Chr XIV from 613171-611837, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YNL011C is not an essential gene" |
| 4480 | YNL012W | SPO1 SGDID:S000004957, Chr XIV from 609687-609791,609876-611666, Verified ORF, "Meiosis-specific protein with similarity to phospholipase B, required for meiotic spindle pole body duplication and separation; required for spore formation" |
| 4481 | YNL014W | HEF3 SGDID:S000004959, Chr XIV from 606320-609454, Verified ORF, "Translational elongation factor EF-3; paralog of YEF3 and member of the ABC superfamily; stimulates EF-1 alpha-dependent binding of aminoacyl-tRNA by the ribosome; normally expressed in zinc deficient cells" |
| 4482 | YNL015W | PBI2 SGDID:S000004960, Chr XIV from 605385-605612, Verified ORF, "Cytosolic inhibitor of vacuolar proteinase B, required for efficient vacuole inheritance; with thioredoxin forms protein complex LMA1, which assists in priming SNARE molecules and promotes vacuole fusion" |
| 4483 | YNL016W | PUB1 SGDID:S000004961, Chr XIV from 602908-604269, Verified ORF, "Poly(A)+ RNA-binding protein, abundant mRNP-component protein that binds mRNA and is required for stability of a number of mRNAs; not reported to associate with polyribosomes" |
| 4484 | YNL018C | YNL018C SGDID:S000004963, Chr XIV from 601775-599937, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 4485 | YNL019C | YNL019C SGDID:S000004964, Chr XIV from 599231-598377, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 4486 | YNL020C | ARK1 SGDID:S000004965, Chr XIV from 597540-595624, reverse complement, Verified ORF, "Serine/threonine protein kinase involved in regulation of the cortical actin cytoskeleton; involved in control of endocytosis" |
| 4487 | YNL021W | HDA1 SGDID:S000004966, Chr XIV from 593228-595348, Verified ORF, "Putative catalytic subunit of a class II histone deacetylase complex that also contains Hda2p and Hda3p; Hda1p interacts with the Hda2p-Hda3p subcomplex to form an active tetramer; deletion increases histone H2B, H3 and H4 acetylation" |
| 4488 | YNL022C | YNL022C SGDID:S000004967, Chr XIV from 592900-591428, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with seven beta-strand methyltransferase motif similar to NOP2/YNL061W; green fluorescent protein (GFP)-fusion protein localizes to a single spot in the nucleus; YNL022C is not an essential gene" |
| 4489 | YNL023C | FAP1 SGDID:S000004968, Chr XIV from 591161-588264, reverse complement, Verified ORF, "Protein that binds to Fpr1p (FKBP12), conferring rapamycin resistance by competing with rapamycin for Fpr1p binding; has similarity to putative transcription factors, including D. melanogaster shuttle craft and human NFX1" |
| 4490 | YNL024C | YNL024C SGDID:S000004969, Chr XIV from 587848-587108, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with seven beta-strand methyltransferase motif; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL024C is not an essential gene" |
| 4491 | YNL024C-A | YNL024C-A SGDID:S000028698, Chr XIV from 586821-586603, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YNL024C-A is an essential gene" |
| 4492 | YNL025C | SSN8 SGDID:S000004970, Chr XIV from 585292-584321, reverse complement, Verified ORF, "Cyclin-like component of the RNA polymerase II holoenzyme, involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression and telomere maintenance" |
| 4493 | YNL026W | SAM50 SGDID:S000004971, Chr XIV from 581921-583375, Verified ORF, "Essential component of the Sorting and Assembly Machinery (SAM or Tob complex) of the mitochondrial outer membrane, which binds precursors of beta-barrel proteins and facilitates their outer membrane insertion; homologous to bacterial Omp85" |
| 4494 | YNL027W | CRZ1 SGDID:S000004972, Chr XIV from 579581-581617, Verified ORF, "Transcription factor that activates transcription of genes involved in stress response; nuclear localization is positively regulated by calcineurin-mediated dephosphorylation" |
| 4495 | YNL029C | KTR5 SGDID:S000004974, Chr XIV from 578774-577206, reverse complement, Verified ORF, "Putative mannosyltransferase involved in protein glycosylation; member of the KRE2/MNT1 mannosyltransferase family" |
| 4496 | YNL030W | HHF2 SGDID:S000004975, Chr XIV from 576728-577039, Verified ORF, "One of two identical histone H4 proteins (see also HHF1); core histone required for chromatin assembly and chromosome function; contributes to telomeric silencing; N-terminal domain involved in maintaining genomic integrity" |
| 4497 | YNL031C | HHT2 SGDID:S000004976, Chr XIV from 576051-575641, reverse complement, Verified ORF, "One of two identical histone H3 proteins (see also HHT1); core histone required for chromatin assembly, involved in heterochromatin-mediated telomeric and HM silencing; regulated by acetylation, methylation, and mitotic phosphorylation" |
| 4498 | YNL032W | SIW14 SGDID:S000004977, Chr XIV from 574507-575352, Verified ORF, "Tyrosine phosphatase that plays a role in actin filament organization and endocytosis; localized to the cytoplasm" |
| 4499 | YNL033W | YNL033W SGDID:S000004978, Chr XIV from 573000-573854, Uncharacterized ORF, "Putative protein of unknown function" |
| 4500 | YNL034W | YNL034W SGDID:S000004979, Chr XIV from 570478-572316, Uncharacterized ORF, "Putative protein of unknown function; YNL034W is not an essential gene" |
| 4501 | YNL035C | YNL035C SGDID:S000004980, Chr XIV from 569692-568523, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with similarity to proteins containing WD-40 domains; green fluorescent protein (GFP)-fusion protein localizes to the nucleus; YNL035C is not an essential gene" |
| 4502 | YNL036W | NCE103 SGDID:S000004981, Chr XIV from 559815-560480, Verified ORF, "Carbonic anhydrase; poorly transcribed under aerobic conditions and at an undetectable level under anaerobic conditions; involved in non-classical protein export pathway" |
| 4503 | YNL037C | IDH1 SGDID:S000004982, Chr XIV from 559003-557921, reverse complement, Verified ORF, "Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle" |
| 4504 | YNL038W | GPI15 SGDID:S000004983, Chr XIV from 557021-557611,557686-557784, Verified ORF, "Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-H protein" |
| 4505 | YNL039W | BDP1 SGDID:S000004984, Chr XIV from 555049-556833, Verified ORF, "Essential subunit of RNA polymerase III transcription factor (TFIIIB), which is involved in transcription of genes encoding tRNAs, 5S rRNA, U6 snRNA, and other small RNAs" |
| 4506 | YNL040W | YNL040W SGDID:S000004985, Chr XIV from 553381-554751, Uncharacterized ORF, "Putative protein of unknown function with strong similarity to alanyl-tRNA synthases from Eubacteria; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL040W is not an essential gene" |
| 4507 | YNL041C | COG6 SGDID:S000004986, Chr XIV from 551988-549469, reverse complement, Verified ORF, "Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" |
| 4508 | YNL042W | BOP3 SGDID:S000004987, Chr XIV from 548101-549291, Verified ORF, "Protein of unknown function, potential Cdc28p substrate; overproduction suppresses a pam1 slv3 double null mutation and confers resistance to methylmercury" |
| 4509 | YNL042W-B | YNL042W-B SGDID:S000028850, Chr XIV from 547114-547371, Uncharacterized ORF, "Putative protein of unknown function" |
| 4510 | YNL044W | YIP3 SGDID:S000004989, Chr XIV from 545269-545292,545372-545878, Verified ORF, "Protein localized to COPII vesicles, proposed to be involved in ER to Golgi transport; interacts with members of the Rab GTPase family and Yip1p; also interacts with Rtn1p" |
| 4511 | YNL045W | YNL045W SGDID:S000004990, Chr XIV from 542964-544979, Verified ORF, "Leucyl aminopeptidase (leukotriene A4 hydrolase) with epoxide hydrolase activity, metalloenzyme containing one zinc atom; role in vivo is not defined; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
| 4512 | YNL046W | YNL046W SGDID:S000004991, Chr XIV from 542305-542823, Uncharacterized ORF, "Putative protein of unknown function; expression depends on Swi5p; GFP-fusion protein localizes to the endoplasmic reticulum; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO)" |
| 4513 | YNL047C | SLM2 SGDID:S000004992, Chr XIV from 541882-539912, reverse complement, Verified ORF, "Phosphoinositide PI4,5P(2) binding protein, forms a complex with Slm1p; acts downstream of Mss4p in a pathway regulating actin cytoskeleton organization in response to stress; subunit of and phosphorylated by the TORC2 complex" |
| 4514 | YNL048W | ALG11 SGDID:S000004993, Chr XIV from 538174-539820, Verified ORF, "Alpha-1,2-mannosyltransferase, catalyzes sequential addition of the two terminal alpha 1,2-mannose residues to the Man5GlcNAc2-PP-dolichol intermediate during asparagine-linked glycosylation in the ER" |
| 4515 | YNL049C | SFB2 SGDID:S000004994, Chr XIV from 537912-535282, reverse complement, Verified ORF, "Probable component of COPII coated vesicles that binds to Sec23p; similar to and functionally redundant with Sec24p, but expressed at low levels; involved in ER to Golgi transport and in autophagy" |
| 4516 | YNL050C | YNL050C SGDID:S000004995, Chr XIV from 534983-534967,534875-534080, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YNL050c is not an essential gene" |
| 4517 | YNL051W | COG5 SGDID:S000004996, Chr XIV from 532660-533871, Verified ORF, "Component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" |
| 4518 | YNL052W | COX5A SGDID:S000004997, Chr XIV from 531726-532187, Verified ORF, "Subunit Va of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; predominantly expressed during aerobic growth while its isoform Vb (Cox5Bp) is expressed during anaerobic growth" |
| 4519 | YNL053W | MSG5 SGDID:S000004998, Chr XIV from 529943-531412, Verified ORF, "Dual-specificity protein phosphatase required for maintenance of a low level of signaling through the cell integrity pathway; regulates and is regulated by Slt2p; dephosphorylates Fus3p; required for adaptive response to pheromone" |
| 4520 | YNL054W | VAC7 SGDID:S000004999, Chr XIV from 526087-529584, Verified ORF, "Integral vacuolar membrane protein involved in vacuole inheritance and morphology; activates Fab1p kinase activity under basal conditions and also after hyperosmotic shock" |
| 4521 | YNL054W-A | YNL054W-A SGDID:S000007384, Chr XIV from 519457-520779, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 4522 | YNL055C | POR1 SGDID:S000005000, Chr XIV from 518846-517995, reverse complement, Verified ORF, "Mitochondrial porin (voltage-dependent anion channel), outer membrane protein required for the maintenance of mitochondrial osmotic stability and mitochondrial membrane permeability; phosphorylated" |
| 4523 | YNL056W | OCA2 SGDID:S000005001, Chr XIV from 517250-517843, Verified ORF, "Putative protein with similarity to predicted tyrosine phosphatases Oca1p and Siw14p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YNL056W is not an essential gene" |
| 4524 | YNL058C | YNL058C SGDID:S000005003, Chr XIV from 516714-515764, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL058C is not an essential gene" |
| 4525 | YNL059C | ARP5 SGDID:S000005004, Chr XIV from 514936-512669, reverse complement, Verified ORF, "Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes" |
| 4526 | YNL061W | NOP2 SGDID:S000005005, Chr XIV from 510541-512397, Verified ORF, "Probable RNA m(5)C methyltransferase, essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; localized to the nucleolus; constituent of 66S pre-ribosomal particles" |
| 4527 | YNL062C | GCD10 SGDID:S000005006, Chr XIV from 510213-508777, reverse complement, Verified ORF, "Subunit of tRNA (1-methyladenosine) methyltransferase with Gcd14p, required for the modification of the adenine at position 58 in tRNAs, especially tRNAi-Met; first identified as a negative regulator of GCN4 expression" |
| 4528 | YNL063W | MTQ1 SGDID:S000005007, Chr XIV from 507759-508703, Verified ORF, "S-adenosylmethionine-dependent methyltransferase; methylates translational release factor Mrf1p; similar to E.coli PrmC; is not an essential gene" |
| 4529 | YNL064C | YDJ1 SGDID:S000005008, Chr XIV from 507098-505869, reverse complement, Verified ORF, "Protein chaperone involved in regulation of the HSP90 and HSP70 functions; involved in protein translocation across membranes; member of the DnaJ family" |
| 4530 | YNL065W | AQR1 SGDID:S000005009, Chr XIV from 503725-505485, Verified ORF, "Plasma membrane multidrug transporter of the major facilitator superfamily, confers resistance to short-chain monocarboxylic acids and quinidine; involved in the excretion of excess amino acids" |
| 4531 | YNL066W | SUN4 SGDID:S000005010, Chr XIV from 501516-502778, Verified ORF, "Cell wall protein related to glucanases, possibly involved in cell wall septation; member of the SUN family" |
| 4532 | YNL067W | RPL9B SGDID:S000005011, Chr XIV from 499682-500257, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl9Ap and has similarity to E. coli L6 and rat L9 ribosomal proteins" |
| 4533 | YNL067W-B | YNL067W-B SGDID:S000028810, Chr XIV from 499418-499558, Uncharacterized ORF, "Putative protein of unknown function" |
| 4534 | YNL068C | FKH2 SGDID:S000005012, Chr XIV from 498290-495702, reverse complement, Verified ORF, "Forkhead family transcription factor with a major role in the expression of G2/M phase genes; positively regulates transcriptional elongation; negative role in chromatin silencing at HML and HMR; substrate of the Cdc28p/Clb5p kinase" |
| 4535 | YNL069C | RPL16B SGDID:S000005013, Chr XIV from 495002-494975,494525-493957, reverse complement, Verified ORF, "N-terminally acetylated protein component of the large (60S) ribosomal subunit, binds to 5.8 S rRNA; has similarity to Rpl16Ap, E. coli L13 and rat L13a ribosomal proteins; transcriptionally regulated by Rap1p" |
| 4536 | YNL070W | TOM7 SGDID:S000005014, Chr XIV from 493367-493549, Verified ORF, "Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex" |
| 4537 | YNL071W | LAT1 SGDID:S000005015, Chr XIV from 491524-492972, Verified ORF, "Dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex, which catalyzes the oxidative decarboxylation of pyruvate to acetyl-CoA" |
| 4538 | YNL072W | RNH201 SGDID:S000005016, Chr XIV from 490318-491241, Verified ORF, "Ribonuclease H2 catalytic subunit, removes RNA primers during Okazaki fragment synthesis; cooperates with Rad27p nuclease; homolog of mammalian RNAse HI (the S. cerevisiae homolog of mammalian RNAse HII is RNH1)" |
| 4539 | YNL073W | MSK1 SGDID:S000005017, Chr XIV from 488387-490117, Verified ORF, "Mitochondrial lysine-tRNA synthetase, required for import of both aminoacylated and deacylated forms of tRNA(Lys) into mitochondria" |
| 4540 | YNL074C | MLF3 SGDID:S000005018, Chr XIV from 488125-486767, reverse complement, Verified ORF, "Serine-rich protein of unknown function; overproduction suppresses the growth inhibition caused by exposure to the immunosuppressant leflunomide" |
| 4541 | YNL075W | IMP4 SGDID:S000005019, Chr XIV from 485608-486480, Verified ORF, "Component of the SSU processome, which is required for pre-18S rRNA processing; interacts with Mpp10p; member of a superfamily of proteins that contain a sigma(70)-like motif and associate with RNAs" |
| 4542 | YNL076W | MKS1 SGDID:S000005020, Chr XIV from 483557-485311, Verified ORF, "Pleiotropic negative transcriptional regulator involved in Ras-CAMP and lysine biosynthetic pathways and nitrogen regulation; involved in retrograde (RTG) mitochondria-to-nucleus signaling" |
| 4543 | YNL077W | APJ1 SGDID:S000005021, Chr XIV from 481392-482978, Verified ORF, "Putative chaperone of the HSP40 (DNAJ) family; overexpression interferes with propagation of the [Psi+] prion; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 4544 | YNL078W | NIS1 SGDID:S000005022, Chr XIV from 479769-480992, Verified ORF, "Protein localized in the bud neck at G2/M phase; physically interacts with septins; possibly involved in a mitotic signaling network" |
| 4545 | YNL079C | TPM1 SGDID:S000005023, Chr XIV from 479166-478567, reverse complement, Verified ORF, "Major isoform of tropomyosin; binds to and stabilizes actin cables and filaments, which direct polarized cell growth and the distribution of several organelles; acetylated by the NatB complex and acetylated form binds actin most efficiently" |
| 4546 | YNL080C | EOS1 SGDID:S000005024, Chr XIV from 478033-476933, reverse complement, Verified ORF, "Protein involved in N-glycosylation; deletion mutation confers sensitivity to exidative stress and shows synthetic lethality with mutations in the spindle checkpoint genes BUB3 and MAD1; YNL080C is not an essential gene" |
| 4547 | YNL081C | SWS2 SGDID:S000005025, Chr XIV from 476620-476189, reverse complement, Verified ORF, "Putative mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S13 ribosomal protein; participates in controlling sporulation efficiency" |
| 4548 | YNL082W | PMS1 SGDID:S000005026, Chr XIV from 473392-476013, Verified ORF, "ATP-binding protein required for mismatch repair in mitosis and meiosis; functions as a heterodimer with Mlh1p, binds double- and single-stranded DNA via its N-terminal domain, similar to E. coli MutL" |
| 4549 | YNL083W | SAL1 SGDID:S000005027, Chr XIV from 471379-473016, Verified ORF, "Probable transporter, member of the Ca2+-binding subfamily of the mitochondrial carrier family, with two EF-hand motifs; Pet9p and Sal1p have an overlapping function critical for viability; polymorphic in different S. cerevisiae strains" |
| 4550 | YNL084C | END3 SGDID:S000005028, Chr XIV from 471104-470055, reverse complement, Verified ORF, "EH domain-containing protein involved in endocytosis, actin cytoskeletal organization and cell wall morphogenesis; forms a complex with Sla1p and Pan1p" |
| 4551 | YNL085W | MKT1 SGDID:S000005029, Chr XIV from 467133-469625, Verified ORF, "Protein that forms a complex with Pbp1p that may mediate posttranscriptional regulation of HO endonuclease; involved in propagation of M2 dsRNA satellite of L-A virus; contains a DTG signature typical of retroviral proteases" |
| 4552 | YNL086W | YNL086W SGDID:S000005030, Chr XIV from 466336-466644, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to endosomes" |
| 4553 | YNL087W | TCB2 SGDID:S000005031, Chr XIV from 462413-465949, Verified ORF, "Bud-specific protein with a potential role in membrane trafficking; GFP-fusion protein migrates from the cell surface to intracellular vesicles near vacuole; contains 3 calcium and lipid binding domains; mRNA is targeted to the bud" |
| 4554 | YNL088W | TOP2 SGDID:S000005032, Chr XIV from 457706-461992, Verified ORF, "Essential type II topoisomerase, relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone of both positively and negatively supercoiled DNA; cleaves complementary strands; localizes to axial cores in meiosis" |
| 4555 | YNL090W | RHO2 SGDID:S000005034, Chr XIV from 456567-457145, Verified ORF, "Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, involved in the establishment of cell polarity and in microtubule assembly" |
| 4556 | YNL091W | NST1 SGDID:S000005035, Chr XIV from 452410-456132, Verified ORF, "Protein of unknown function, mediates sensitivity to salt stress; interacts physically with the splicing factor Msl1p and also displays genetic interaction with MSL1" |
| 4557 | YNL092W | YNL092W SGDID:S000005036, Chr XIV from 450873-452075, Uncharacterized ORF, "Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family; YNL092W is not an essential gene" |
| 4558 | YNL093W | YPT53 SGDID:S000005037, Chr XIV from 449870-450532, Verified ORF, "GTPase, similar to Ypt51p and Ypt52p and to mammalian rab5; required for vacuolar protein sorting and endocytosis" |
| 4559 | YNL094W | APP1 SGDID:S000005038, Chr XIV from 447613-449376, Verified ORF, "Protein of unknown function, interacts with Rvs161p and Rvs167p; computational analysis of protein-protein interactions in large-scale studies suggests a possible role in actin filament organization" |
| 4560 | YNL095C | YNL095C SGDID:S000005039, Chr XIV from 446842-444914, reverse complement, Uncharacterized ORF, "Putative protein of unknown function predicted to contain a transmembrane domain; YNL095C is not an essential gene" |
| 4561 | YNL096C | RPS7B SGDID:S000005040, Chr XIV from 444317-444174,443828-443400, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Ap; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins" |
| 4562 | YNL097C | PHO23 SGDID:S000005041, Chr XIV from 442360-441368, reverse complement, Verified ORF, "Probable component of the Rpd3 histone deacetylase complex, involved in transcriptional regulation of PHO5; C-terminus has similarity to human candidate tumor suppressor p33(ING1)" |
| 4563 | YNL097C-B | YNL097C-B SGDID:S000028699, Chr XIV from 440921-440799, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 4564 | YNL098C | RAS2 SGDID:S000005042, Chr XIV from 440572-439604, reverse complement, Verified ORF, "GTP-binding protein that regulates the nitrogen starvation response, sporulation, and filamentous growth; farnesylation and palmitoylation required for activity and localization to plasma membrane; homolog of mammalian Ras proto-oncogenes" |
| 4565 | YNL099C | OCA1 SGDID:S000005043, Chr XIV from 439285-438569, reverse complement, Verified ORF, "Putative protein tyrosine phosphatase, required for cell cycle arrest in response to oxidative damage of DNA" |
| 4566 | YNL100W | YNL100W SGDID:S000005044, Chr XIV from 437615-438319, Uncharacterized ORF, "Putative protein of unknown function; non-tagged protein is detected in purified mitochondria; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media" |
| 4567 | YNL101W | AVT4 SGDID:S000005045, Chr XIV from 435001-437142, Verified ORF, "Vacuolar transporter, exports large neutral amino acids from the vacuole; member of a family of seven S. cerevisiae genes (AVT1-7) related to vesicular GABA-glycine transporters" |
| 4568 | YNL102W | POL1 SGDID:S000005046, Chr XIV from 430089-434495, Verified ORF, "Catalytic subunit of the DNA polymerase I alpha-primase complex, required for the initiation of DNA replication during mitotic DNA synthesis and premeiotic DNA synthesis" |
| 4569 | YNL103W | MET4 SGDID:S000005047, Chr XIV from 427737-429755, Verified ORF, "Leucine-zipper transcriptional activator, responsible for the regulation of the sulfur amino acid pathway, requires different combinations of the auxiliary factors Cbf1p, Met28p, Met31p and Met32p" |
| 4570 | YNL104C | LEU4 SGDID:S000005048, Chr XIV from 426756-424897, reverse complement, Verified ORF, "Alpha-isopropylmalate synthase (2-isopropylmalate synthase); the main isozyme responsible for the first step in the leucine biosynthesis pathway" |
| 4571 | YNL106C | INP52 SGDID:S000005050, Chr XIV from 424497-420946, reverse complement, Verified ORF, "Polyphosphatidylinositol phosphatase, dephosphorylates a number of phosphatidylinositols (PIs) to PI; involved in endocytosis; hyperosmotic stress causes translocation to actin patches; synaptojanin-like protein with a Sac1 domain" |
| 4572 | YNL107W | YAF9 SGDID:S000005051, Chr XIV from 420100-420780, Verified ORF, "Subunit of both the NuA4 histone H4 acetyltransferase complex and the SWR1 complex, may function to antagonize silencing near telomeres; interacts directly with Swc4p, has homology to human leukemogenic protein AF9, contains a YEATS domain" |
| 4573 | YNL108C | YNL108C SGDID:S000005052, Chr XIV from 419828-419016, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with similarity to Tfc7p and prokaryotic phosphotransfer enzymes; null mutant shows alterations in glucose metabolism; GFP-fusion protein localizes to the cytoplasm and nucleus" |
| 4574 | YNL110C | NOP15 SGDID:S000005054, Chr XIV from 418490-417828, reverse complement, Verified ORF, "Constituent of 66S pre-ribosomal particles, involved in 60S ribosomal subunit biogenesis; localizes to both nucleolus and cytoplasm" |
| 4575 | YNL111C | CYB5 SGDID:S000005055, Chr XIV from 417304-416942, reverse complement, Verified ORF, "Cytochrome b5, involved in the sterol and lipid biosynthesis pathways; acts as an electron donor to support sterol C5-6 desaturation" |
| 4576 | YNL112W | DBP2 SGDID:S000005056, Chr XIV from 413641-414913,415916-416283, Verified ORF, "Essential ATP-dependent RNA helicase of the DEAD-box protein family, involved in nonsense-mediated mRNA decay and rRNA processing" |
| 4577 | YNL113W | RPC19 SGDID:S000005057, Chr XIV from 412773-413201, Verified ORF, "RNA polymerase subunit, common to RNA polymerases I and III" |
| 4578 | YNL115C | YNL115C SGDID:S000005059, Chr XIV from 412055-410121, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YNL115C is not an essential gene" |
| 4579 | YNL116W | DMA2 SGDID:S000005060, Chr XIV from 408343-409911, Verified ORF, "Protein involved in ubiquitin ligation; plays a role in regulating spindle position and orientation; functionally redundant with Dma1p; orthologous to human RNF8 protein, also has sequence similarity to human Chfr." |
| 4580 | YNL117W | MLS1 SGDID:S000005061, Chr XIV from 406360-408024, Verified ORF, "Malate synthase, enzyme of the glyoxylate cycle, involved in utilization of non-fermentable carbon sources; expression is subject to carbon catabolite repression; localizes in peroxisomes during growth in oleic acid medium" |
| 4581 | YNL118C | DCP2 SGDID:S000005062, Chr XIV from 405566-402654, reverse complement, Verified ORF, "Catalytic subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; member of the Nudix hydrolase family" |
| 4582 | YNL119W | NCS2 SGDID:S000005063, Chr XIV from 401042-402523, Uncharacterized ORF, "Protein with a role in urmylation and in invasive and pseudohyphal growth; inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts" |
| 4583 | YNL121C | TOM70 SGDID:S000005065, Chr XIV from 400539-398686, reverse complement, Verified ORF, "Component (70 kDa) of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; acts as a receptor for incoming precursor proteins" |
| 4584 | YNL122C | YNL122C SGDID:S000005066, Chr XIV from 398372-398025, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YNL122C is not an essential gene" |
| 4585 | YNL123W | NMA111 SGDID:S000005067, Chr XIV from 394687-397680, Verified ORF, "Protein of unknown function which may contribute to lipid homeostasis and/or apoptosis; sequence similarity to the mammalian Omi/HtrA2 family of serine proteases" |
| 4586 | YNL124W | NAF1 SGDID:S000005068, Chr XIV from 392894-394372, Verified ORF, "Protein required for the assembly of box H/ACA snoRNPs and for pre-rRNA processing, forms a complex with Shq1p and interacts with H/ACA snoRNP components Nhp2p and Cbf5p; has similarity to Gar1p and other RNA-binding proteins" |
| 4587 | YNL125C | ESBP6 SGDID:S000005069, Chr XIV from 392169-390148, reverse complement, Verified ORF, "Protein with similarity to monocarboxylate permeases, appears not to be involved in transport of monocarboxylates such as lactate, pyruvate or acetate across the plasma membrane" |
| 4588 | YNL126W | SPC98 SGDID:S000005070, Chr XIV from 387229-389769, Verified ORF, "Component of the microtubule-nucleating Tub4p (gamma-tubulin) complex; interacts with Spc110p at the spindle pole body (SPB) inner plaque and with Spc72p at the SPB outer plaque" |
| 4589 | YNL127W | FAR11 SGDID:S000005071, Chr XIV from 383989-386850, Verified ORF, "Protein involved in G1 cell cycle arrest in response to pheromone, in a pathway different from the Far1p-dependent pathway; interacts with Far3p, Far7p, Far8p, Far9p, and Far10p" |
| 4590 | YNL128W | TEP1 SGDID:S000005072, Chr XIV from 382361-383665, Verified ORF, "Homolog of human tumor suppressor gene PTEN/MMAC1/TEP1 that has lipid phosphatase activity and is linked to the phosphatidylinositol signaling pathway; plays a role in normal sporulation" |
| 4591 | YNL129W | NRK1 SGDID:S000005073, Chr XIV from 381482-382204, Verified ORF, "Nicotinamide riboside kinase, catalyzes the phosphorylation of nicotinamide riboside and nicotinic acid riboside in salvage pathways for NAD+ biosynthesis" |
| 4592 | YNL130C | CPT1 SGDID:S000005074, Chr XIV from 380833-380784,380691-379560, reverse complement, Verified ORF, "Cholinephosphotransferase, required for phosphatidylcholine biosynthesis and for inositol-dependent regulation of EPT1 transcription" |
| 4593 | YNL130C-A | YNL130C-A SGDID:S000028579, Chr XIV from 381393-381247, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 4594 | YNL131W | TOM22 SGDID:S000005075, Chr XIV from 378769-379227, Verified ORF, "Component of the TOM (translocase of outer membrane) complex responsible for initial import of mitochondrially directed proteins; acts as a receptor for precursor proteins and mediates interaction between the TOM and TIM complexes" |
| 4595 | YNL132W | KRE33 SGDID:S000005076, Chr XIV from 375323-378493, Verified ORF, "Essential protein of unknown function; heterozygous mutant shows haploinsufficiency in K1 killer toxin resistance" |
| 4596 | YNL133C | FYV6 SGDID:S000005077, Chr XIV from 374694-374173, reverse complement, Verified ORF, "Protein of unknown function, required for survival upon exposure to K1 killer toxin; proposed to regulate double-strand break repair via non-homologous end-joining" |
| 4597 | YNL134C | YNL134C SGDID:S000005078, Chr XIV from 373583-372453, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with similarity to dehydrogenases from other model organisms; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and nucleus and is induced by the DNA-damaging agent MMS" |
| 4598 | YNL135C | FPR1 SGDID:S000005079, Chr XIV from 372228-371884, reverse complement, Verified ORF, "Peptidyl-prolyl cis-trans isomerase (PPIase), binds to the drugs FK506 and rapamycin; also binds to the nonhistone chromatin binding protein Hmo1p and may regulate its assembly or function" |
| 4599 | YNL136W | EAF7 SGDID:S000005080, Chr XIV from 370370-371647, Verified ORF, "Subunit of the NuA4 histone acetyltransferase complex, which acetylates the N-terminal tails of histones H4 and H2A" |
| 4600 | YNL137C | NAM9 SGDID:S000005081, Chr XIV from 370057-368597, reverse complement, Verified ORF, "Mitochondrial ribosomal component of the small subunit" |
| 4601 | YNL138W | SRV2 SGDID:S000005082, Chr XIV from 366743-368323, Verified ORF, "CAP (cyclase-associated protein) subunit of adenylyl cyclase complex; N-terminus binds adenylyl cyclase and facilitates activation by RAS; C-terminus binds ADP-actin monomers, facilitating regulation of actin dynamics and cell morphogenesis" |
| 4602 | YNL138W-A | YSF3 SGDID:S000028509, Chr XIV from 366035-366037,366160-366414, Verified ORF, "Component of the U2 snRNP, associated with the SF3b complex; conserved in Ashbya gossypii" |
| 4603 | YNL139C | THO2 SGDID:S000005083, Chr XIV from 365719-360926, reverse complement, Verified ORF, "Subunit of the THO complex, which is required for efficient transcription elongation and involved in transcriptional elongation-associated recombination; required for LacZ RNA expression from certain plasmids" |
| 4604 | YNL141W | AAH1 SGDID:S000005085, Chr XIV from 359598-360641, Verified ORF, "Adenine deaminase (adenine aminohydrolase), converts adenine to hypoxanthine; involved in purine salvage; transcriptionally regulated by nutrient levels and growth phase; Aah1p degraded upon entry into quiescence via SCF and the proteasome" |
| 4605 | YNL142W | MEP2 SGDID:S000005086, Chr XIV from 357455-358954, Verified ORF, "Ammonium permease involved in regulation of pseudohyphal growth; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation" |
| 4606 | YNL144C | YNL144C SGDID:S000005088, Chr XIV from 355044-352822, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies; YNL144C is not an essential gene" |
| 4607 | YNL145W | MFA2 SGDID:S000005089, Chr XIV from 352416-352532, Verified ORF, "Mating pheromone a-factor, made by a cells; interacts with alpha cells to induce cell cycle arrest and other responses leading to mating; biogenesis involves C-terminal modification, N-terminal proteolysis, and export; also encoded by MFA1" |
| 4608 | YNL146C-A | YNL146C-A SGDID:S000028851, Chr XIV from 351582-351388, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 4609 | YNL146W | YNL146W SGDID:S000005090, Chr XIV from 351717-352019, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YNL146W is not an essential gene" |
| 4610 | YNL147W | LSM7 SGDID:S000005091, Chr XIV from 350942-350959,351056-351385, Verified ORF, "Lsm (Like Sm) protein; part of heteroheptameric complexes (Lsm2p-7p and either Lsm1p or 8p): cytoplasmic Lsm1p complex involved in mRNA decay; nuclear Lsm8p complex part of U6 snRNP and possibly involved in processing tRNA, snoRNA, and rRNA" |
| 4611 | YNL148C | ALF1 SGDID:S000005092, Chr XIV from 350673-349909, reverse complement, Verified ORF, "Alpha-tubulin folding protein, similar to mammalian cofactor B; Alf1p-GFP localizes to cytoplasmic microtubules; required for the folding of alpha-tubulin and may play an additional role in microtubule maintenance" |
| 4612 | YNL149C | PGA2 SGDID:S000005093, Chr XIV from 349758-349369, reverse complement, Uncharacterized ORF, "Essential protein required for maturation of Gas1p and Pho8p; involved in protein trafficking; GFP-fusion protein localizes to the ER and YFP-fusion protein to the nuclear envelope-ER network; null mutants have a cell separation defect" |
| 4613 | YNL151C | RPC31 SGDID:S000005095, Chr XIV from 348523-347768, reverse complement, Verified ORF, "RNA polymerase III subunit C31; contains HMG-like C-terminal domain" |
| 4614 | YNL152W | INN1 SGDID:S000005096, Chr XIV from 346315-347544, Verified ORF, "Essential protein that associates with the contractile actomyosin ring, required for ingression of the plasma membrane into the bud neck during cytokinesis; C2 domain, a membrane targeting module, is required for function" |
| 4615 | YNL153C | GIM3 SGDID:S000005097, Chr XIV from 346060-345671, reverse complement, Verified ORF, "Subunit of the heterohexameric cochaperone prefoldin complex which binds specifically to cytosolic chaperonin and transfers target proteins to it" |
| 4616 | YNL154C | YCK2 SGDID:S000005098, Chr XIV from 345278-343638, reverse complement, Verified ORF, "Palmitoylated, plasma membrane-bound casein kinase I isoform; shares redundant functions with Yck1p in morphogenesis, proper septin assembly, endocytic trafficking; provides an essential function overlapping with that of Yck1p" |
| 4617 | YNL155W | YNL155W SGDID:S000005099, Chr XIV from 342518-343342, Uncharacterized ORF, "Putative protein of unknown function, contains DHHC domain, also predicted to have thiol-disulfide oxidoreductase active site" |
| 4618 | YNL156C | NSG2 SGDID:S000005100, Chr XIV from 341970-341071, reverse complement, Verified ORF, "Protein involved in regulation of sterol biosynthesis; specifically stabilizes Hmg2p, one of two HMG-CoA isoenzymes that catalyze the rate-limiting step in sterol biosynthesis; homolog of mammalian INSIG proteins" |
| 4619 | YNL157W | YNL157W SGDID:S000005101, Chr XIV from 340354-340860, Uncharacterized ORF, "Hypothetical protein" |
| 4620 | YNL158W | PGA1 SGDID:S000005102, Chr XIV from 339614-340210, Verified ORF, "Essential component of GPI-mannosyltransferase II, responsible for second mannose addition to GPI precursors as a partner of Gpi18p; required for maturation of Gas1p and Pho8p; has synthetic genetic interations with secretory pathway genes" |
| 4621 | YNL159C | ASI2 SGDID:S000005103, Chr XIV from 339349-338480, reverse complement, Verified ORF, "Integral inner nuclear membrane protein that acts with Asi1p and Asi3p to ensure the fidelity of SPS-sensor signalling by maintaining the dormant repressed state of gene expression in the absence of inducing signals" |
| 4622 | YNL160W | YGP1 SGDID:S000005104, Chr XIV from 336547-337611, Verified ORF, "Cell wall-related secretory glycoprotein; induced by nutrient deprivation-associated growth arrest and upon entry into stationary phase; may be involved in adaptation prior to stationary phase entry; has similarity to Sps100p" |
| 4623 | YNL161W | CBK1 SGDID:S000005105, Chr XIV from 332599-334869, Verified ORF, "Serine/threonine protein kinase that regulates cell morphogenesis pathways; involved in cell wall biosynthesis, apical growth, proper mating projection morphology, bipolar bud site selection in diploid cells, and cell separation" |
| 4624 | YNL162W | RPL42A SGDID:S000005106, Chr XIV from 331324-331327,331840-332156, Verified ORF, "Protein component of the large (60S) ribosomal subunit, identical to Rpl42Bp and has similarity to rat L44 ribosomal protein" |
| 4625 | YNL162W-A | YNL162W-A SGDID:S000007624, Chr XIV from 330331-330549, Uncharacterized ORF, "Putative protein of unknown function, identified by homology" |
| 4626 | YNL163C | RIA1 SGDID:S000005107, Chr XIV from 330075-326743, reverse complement, Verified ORF, "Cytoplasmic GTPase involved in biogenesis of the 60S ribosome; has similarity to translation elongation factor 2 (Eft1p and Eft2p)" |
| 4627 | YNL164C | IBD2 SGDID:S000005108, Chr XIV from 326322-325267, reverse complement, Verified ORF, "Component of the BUB2-dependent spindle checkpoint pathway, interacts with Bfa1p and functions upstream of Bub2p and Bfa1p" |
| 4628 | YNL165W | YNL165W SGDID:S000005109, Chr XIV from 323834-325054, Uncharacterized ORF, "Putative protein of unknown function; YNL165W is not an essential gene" |
| 4629 | YNL166C | BNI5 SGDID:S000005110, Chr XIV from 323567-322221, reverse complement, Verified ORF, "Protein involved in organization of septins at the mother-bud neck, may interact directly with the Cdc11p septin, localizes to bud neck in a septin-dependent manner" |
| 4630 | YNL167C | SKO1 SGDID:S000005111, Chr XIV from 321361-319418, reverse complement, Verified ORF, "Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, forms a complex with Tup1p and Ssn6p to both activate and repress transcription; cytosolic and nuclear protein involved in osmotic and oxidative stress responses" |
| 4631 | YNL168C | YNL168C SGDID:S000005112, Chr XIV from 318811-318032, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; GFP-fusion protein is induced in response to the DNA-damaging agent MMS; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 4632 | YNL169C | PSD1 SGDID:S000005113, Chr XIV from 317673-316171, reverse complement, Verified ORF, "Phosphatidylserine decarboxylase of the mitochondrial inner membrane, converts phosphatidylserine to phosphatidylethanolamine" |
| 4633 | YNL172W | APC1 SGDID:S000005116, Chr XIV from 310638-315884, Verified ORF, "Largest subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" |
| 4634 | YNL173C | MDG1 SGDID:S000005117, Chr XIV from 310059-308959, reverse complement, Verified ORF, "Plasma membrane protein involved in G-protein mediated pheromone signaling pathway; overproduction suppresses bem1 mutations" |
| 4635 | YNL175C | NOP13 SGDID:S000005119, Chr XIV from 308614-307403, reverse complement, Verified ORF, "Protein of unknown function, localizes to the nucleolus and nucleoplasm; contains an RNA recognition motif (RRM) and has similarity to Nop12p, which is required for processing of pre-18S rRNA" |
| 4636 | YNL176C | YNL176C SGDID:S000005120, Chr XIV from 306982-305072, reverse complement, Uncharacterized ORF, "Cell cycle-regulated gene of unknown function, promoter bound by Fkh2p" |
| 4637 | YNL177C | MRPL22 SGDID:S000005121, Chr XIV from 304617-303688, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 4638 | YNL178W | RPS3 SGDID:S000005122, Chr XIV from 302682-303404, Verified ORF, "Protein component of the small (40S) ribosomal subunit, has apurinic/apyrimidinic (AP) endonuclease activity; essential for viability; has similarity to E. coli S3 and rat S3 ribosomal proteins" |
| 4639 | YNL180C | RHO5 SGDID:S000005124, Chr XIV from 300651-299656, reverse complement, Verified ORF, "Non-essential small GTPase of the Rho/Rac subfamily of Ras-like proteins, likely involved in protein kinase C (Pkc1p)-dependent signal transduction pathway that controls cell integrity" |
| 4640 | YNL181W | YNL181W SGDID:S000005125, Chr XIV from 298337-299560, Uncharacterized ORF, "Putative oxidoreductase; required for cell viability" |
| 4641 | YNL182C | IPI3 SGDID:S000005126, Chr XIV from 297629-295962, reverse complement, Verified ORF, "Essential component of the Rix1 complex (Rix1p, Ipi1p, Ipi3p) that is required for processing of ITS2 sequences from 35S pre-rRNA; highly conserved and contains WD40 motifs; Rix1 complex associates with Mdn1p in pre-60S ribosomal particles" |
| 4642 | YNL183C | NPR1 SGDID:S000005127, Chr XIV from 295511-293139, reverse complement, Verified ORF, "Protein kinase that stabilizes several plasma membrane amino acid transporters by antagonizing their ubiquitin-mediated degradation" |
| 4643 | YNL185C | MRPL19 SGDID:S000005129, Chr XIV from 292671-292195, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 4644 | YNL186W | UBP10 SGDID:S000005130, Chr XIV from 289500-291878, Verified ORF, "Ubiquitin-specific protease that deubiquitinates ubiquitin-protein moieties; may regulate silencing by acting on Sir4p; involved in posttranscriptionally regulating Gap1p and possibly other transporters; primarily located in the nucleus" |
| 4645 | YNL187W | YNL187W SGDID:S000005131, Chr XIV from 287996-289069, Uncharacterized ORF, "Putative protein of unknown function; contains a consensus nuclear export signal (NES) sequence similar to the consensus sequence recognized by Crm1p; may interact with or be fuctionally redundant with Prp40p" |
| 4646 | YNL188W | KAR1 SGDID:S000005132, Chr XIV from 286309-287610, Verified ORF, "Essential protein involved in karyogamy during mating and in spindle pole body duplication during mitosis, localizes to the half-bridge of the spindle pole body, interacts with Spc72p during karyogamy, also interacts with Cdc31p" |
| 4647 | YNL189W | SRP1 SGDID:S000005133, Chr XIV from 284261-285889, Verified ORF, "Karyopherin alpha homolog, forms a dimer with karyopherin beta Kap95p to mediate import of nuclear proteins, binds the nuclear localization signal of the substrate during import; may also play a role in regulation of protein degradation" |
| 4648 | YNL190W | YNL190W SGDID:S000005134, Chr XIV from 282396-283010, Uncharacterized ORF, "Cell wall protein of unknown function; proposed role as a hydrophilin induced by osmotic stress; contains a putative GPI-attachment site" |
| 4649 | YNL191W | DUG3 SGDID:S000005135, Chr XIV from 280433-281506, Verified ORF, "Probable glutamine amidotransferase, forms a complex with Dug1p and Dug2p to degrade glutathione (GSH) and other peptides containing a gamma-glu-X bond in an alternative pathway to GSH degradation by gamma-glutamyl transpeptidase (Ecm38p)" |
| 4650 | YNL192W | CHS1 SGDID:S000005136, Chr XIV from 276503-279898, Verified ORF, "Chitin synthase I, requires activation from zymogenic form in order to catalyze the transfer of N-acetylglucosamine (GlcNAc) to chitin; required for repairing the chitin septum during cytokinesis; transcription activated by mating factor" |
| 4651 | YNL193W | YNL193W SGDID:S000005137, Chr XIV from 274369-276045, Uncharacterized ORF, "Putative protein of unknown function; exhibits a two-hybrid interaction with Yhr151cp in a large-scale analysis" |
| 4652 | YNL194C | YNL194C SGDID:S000005138, Chr XIV from 273616-272711, reverse complement, Verified ORF, "Integral membrane protein localized to eisosomes; sporulation and plasma membrane sphingolipid content are altered in mutants; has homologs SUR7 and FMP45; GFP-fusion protein is induced in response to the DNA-damaging agent MMS" |
| 4653 | YNL195C | YNL195C SGDID:S000005139, Chr XIV from 272309-271524, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; shares a promoter with YNL194C; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 4654 | YNL196C | SLZ1 SGDID:S000005140, Chr XIV from 271172-270276, reverse complement, Uncharacterized ORF, "Sporulation-specific protein with a leucine zipper motif" |
| 4655 | YNL197C | WHI3 SGDID:S000005141, Chr XIV from 269594-267609, reverse complement, Verified ORF, "RNA binding protein that sequesters CLN3 mRNA in cytoplasmic foci; cytoplasmic retention factor for Cdc28p and associated cyclins; regulates cell fate and dose-dependently regulates the critical cell size required for passage through Start" |
| 4656 | YNL199C | GCR2 SGDID:S000005143, Chr XIV from 266531-264927, reverse complement, Verified ORF, "Transcriptional activator of genes involved in glycolysis; interacts and functions with the DNA-binding protein Gcr1p" |
| 4657 | YNL200C | YNL200C SGDID:S000005144, Chr XIV from 264454-263714, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 4658 | YNL201C | PSY2 SGDID:S000005145, Chr XIV from 263204-260628, reverse complement, Verified ORF, "Putative subunit of an evolutionarily conserved protein phosphatase complex containing the catalytic subunit Pph3p and the regulatory subunit Psy4p; required for cisplatin and oxaliplatin resistance; localizes to nucleus" |
| 4659 | YNL202W | SPS19 SGDID:S000005146, Chr XIV from 259579-260457, Verified ORF, "Peroxisomal 2,4-dienoyl-CoA reductase, auxiliary enzyme of fatty acid beta-oxidation; homodimeric enzyme required for growth and sporulation on petroselineate medium; expression induced during late sporulation and in the presence of oleate" |
| 4660 | YNL204C | SPS18 SGDID:S000005148, Chr XIV from 259278-258376, reverse complement, Verified ORF, "Protein of unknown function, contains a putative zinc-binding domain; expressed during sporulation" |
| 4661 | YNL206C | RTT106 SGDID:S000005150, Chr XIV from 258156-256789, reverse complement, Verified ORF, "Protein with a role in regulation of Ty1 transposition" |
| 4662 | YNL207W | RIO2 SGDID:S000005151, Chr XIV from 255354-256631, Verified ORF, "Essential serine kinase involved in the processing of the 20S pre-rRNA into mature 18S rRNA; has similarity to Rio1p" |
| 4663 | YNL208W | YNL208W SGDID:S000005152, Chr XIV from 254419-255018, Verified ORF, "Protein of unknown function; may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein is detected in purified mitochondria in high-throughput studies; potential orthologs found in other fungi" |
| 4664 | YNL209W | SSB2 SGDID:S000005153, Chr XIV from 252060-253901, Verified ORF, "Cytoplasmic ATPase that is a ribosome-associated molecular chaperone, functions with J-protein partner Zuo1p; may be involved in the folding of newly-synthesized polypeptide chains; member of the HSP70 family; homolog of SSB1" |
| 4665 | YNL210W | MER1 SGDID:S000005154, Chr XIV from 250932-251744, Verified ORF, "Protein with RNA-binding motifs required for meiosis-specific mRNA splicing; required for chromosome pairing and meiotic recombination" |
| 4666 | YNL211C | YNL211C SGDID:S000005155, Chr XIV from 250316-250056, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YNL211C is not an essential gene" |
| 4667 | YNL212W | VID27 SGDID:S000005156, Chr XIV from 247462-249810, Verified ORF, "Cytoplasmic protein of unknown function; possibly involved in vacuolar protein degradation; not essential for proteasome-dependent degradation of fructose-1,6-bisphosphatase (FBPase); null mutants exhibit normal growth" |
| 4668 | YNL213C | YNL213C SGDID:S000005157, Chr XIV from 247105-246461, reverse complement, Verified ORF, "Protein of unknown function; null mutant lacks mitochondrial DNA and cannot grow on glycerol; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 4669 | YNL214W | PEX17 SGDID:S000005158, Chr XIV from 245618-246217, Verified ORF, "Peroxisomal membrane peroxin and subunit of the docking complex that facilitates the import of peroxisomal matrix proteins; required for peroxisome biogenesis" |
| 4670 | YNL215W | IES2 SGDID:S000005159, Chr XIV from 244469-245431, Verified ORF, "Protein that associates with the INO80 chromatin remodeling complex under low-salt conditions" |
| 4671 | YNL216W | RAP1 SGDID:S000005160, Chr XIV from 241690-244173, Verified ORF, "DNA-binding protein involved in either activation or repression of transcription, depending on binding site context; also binds telomere sequences and plays a role in telomeric position effect (silencing) and telomere structure" |
| 4672 | YNL217W | YNL217W SGDID:S000005161, Chr XIV from 240332-241312, Uncharacterized ORF, "Hypothetical protein" |
| 4673 | YNL218W | MGS1 SGDID:S000005162, Chr XIV from 238239-240002, Verified ORF, "Protein with DNA-dependent ATPase and ssDNA annealing activities involved in maintenance of genome; interacts functionally with DNA polymerase delta; homolog of human Werner helicase interacting protein (WHIP)" |
| 4674 | YNL219C | ALG9 SGDID:S000005163, Chr XIV from 237664-235997, reverse complement, Verified ORF, "Mannosyltransferase, involved in N-linked glycosylation; catalyzes the transfer of mannose from Dol-P-Man to lipid-linked oligosaccharides; mutation of the human ortholog causes type 1 congenital disorders of glycosylation" |
| 4675 | YNL220W | ADE12 SGDID:S000005164, Chr XIV from 234414-235715, Verified ORF, "Adenylosuccinate synthase, catalyzes the first step in synthesis of adenosine monophosphate from inosine 5'monophosphate during purine nucleotide biosynthesis; exhibits binding to single-stranded autonomously replicating (ARS) core sequence" |
| 4676 | YNL221C | POP1 SGDID:S000005165, Chr XIV from 233696-231069, reverse complement, Verified ORF, "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends; binds to the RPR1 RNA subunit in RNase P" |
| 4677 | YNL222W | SSU72 SGDID:S000005166, Chr XIV from 229095-229715, Verified ORF, "Transcription/RNA-processing factor that associates with TFIIB and cleavage/polyadenylation factor Pta1p; exhibits phosphatase activity on serine-5 of the RNA polymerase II C-terminal domain; affects start site selection in vivo" |
| 4678 | YNL223W | ATG4 SGDID:S000005167, Chr XIV from 227371-228855, Verified ORF, "Conserved cysteine protease required for autophagy; cleaves Atg8p to a form required for autophagosome and Cvt vesicle generation; mediates attachment of autophagosomes to microtubules through interactions with Tub1p and Tub2p" |
| 4679 | YNL224C | SQS1 SGDID:S000005168, Chr XIV from 227100-224797, reverse complement, Verified ORF, "Protein of unknown function; overexpression antagonizes the suppression of splicing defects by spp382 mutants; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus" |
| 4680 | YNL225C | CNM67 SGDID:S000005169, Chr XIV from 224470-222725, reverse complement, Verified ORF, "Component of the spindle pole body outer plaque; required for spindle orientation and mitotic nuclear migration" |
| 4681 | YNL227C | JJJ1 SGDID:S000005171, Chr XIV from 222432-220660, reverse complement, Verified ORF, "Co-chaperone that stimulates the ATPase activity of Ssa1p, required for a late step of ribosome biogenesis; associated with the cytosolic large ribosomal subunit; contains a J-domain; mutation causes defects in fluid-phase endocytosis" |
| 4682 | YNL229C | URE2 SGDID:S000005173, Chr XIV from 220202-219138, reverse complement, Verified ORF, "Nitrogen catabolite repression transcriptional regulator that acts by inhibition of GLN3 transcription in good nitrogen source; altered form of Ure2p creates [URE3] prion" |
| 4683 | YNL230C | ELA1 SGDID:S000005174, Chr XIV from 218663-217524, reverse complement, Verified ORF, "Elongin A, F-box protein that forms a heterodimer with Elc1p and is required for ubiquitin-dependent degredation of the RNA Polymerase II subunit RPO21; subunit of the Elongin-Cullin-Socs (ECS) ligase complex" |
| 4684 | YNL231C | PDR16 SGDID:S000005175, Chr XIV from 217043-215988, reverse complement, Verified ORF, "Phosphatidylinositol transfer protein (PITP) controlled by the multiple drug resistance regulator Pdr1p, localizes to lipid particles and microsomes, controls levels of various lipids, may regulate lipid synthesis, homologous to Pdr17p" |
| 4685 | YNL232W | CSL4 SGDID:S000005176, Chr XIV from 214924-215802, Verified ORF, "Subunit of the exosome, which is an essential complex present in both nucleus and cytoplasm that mediates RNA processing and degradation" |
| 4686 | YNL233W | BNI4 SGDID:S000005177, Chr XIV from 211923-214601, Verified ORF, "Targeting subunit for Glc7p protein phosphatase, localized to the bud neck, required for localization of chitin synthase III to the bud neck via interaction with the chitin synthase III regulatory subunit Skt5p" |
| 4687 | YNL234W | YNL234W SGDID:S000005178, Chr XIV from 210234-211514, Uncharacterized ORF, "Similar to globins and has a functional heme-binding domain; involved in glucose signaling or metabolism; regulated by Rgt1p" |
| 4688 | YNL236W | SIN4 SGDID:S000005180, Chr XIV from 206931-209855, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; contributes to both postive and negative transcriptional regulation; dispensible for basal transcription" |
| 4689 | YNL237W | YTP1 SGDID:S000005181, Chr XIV from 205189-206568, Verified ORF, "Probable type-III integral membrane protein of unknown function, has regions of similarity to mitochondrial electron transport proteins" |
| 4690 | YNL238W | KEX2 SGDID:S000005182, Chr XIV from 202429-204873, Verified ORF, "Subtilisin-like protease (proprotein convertase), a calcium-dependent serine protease involved in the activation of proproteins of the secretory pathway" |
| 4691 | YNL239W | LAP3 SGDID:S000005183, Chr XIV from 200570-201934, Verified ORF, "Cysteine aminopeptidase with homocysteine-thiolactonase activity; protects cells against homocysteine toxicity; has bleomycin hydrolase activity in vitro; transcription is regulated by galactose via Gal4p; orthologous to human BLMH" |
| 4692 | YNL240C | NAR1 SGDID:S000005184, Chr XIV from 199978-198503, reverse complement, Verified ORF, "Nuclear architecture related protein; component of the cytosolic iron-sulfur (FeS) protein assembly machinery, required for maturation of cytosolic and nuclear FeS proteins; homologous to human Narf" |
| 4693 | YNL241C | ZWF1 SGDID:S000005185, Chr XIV from 197944-196427, reverse complement, Verified ORF, "Glucose-6-phosphate dehydrogenase (G6PD), catalyzes the first step of the pentose phosphate pathway; involved in adapting to oxidatve stress; homolog of the human G6PD which is deficient in patients with hemolytic anemia" |
| 4694 | YNL242W | ATG2 SGDID:S000005186, Chr XIV from 191325-196103, Verified ORF, "Peripheral membrane protein required for vesicle formation during autophagy, pexophagy, and the cytoplasm-to-vaucole targeting (Cvt) pathway; involved in Atg9p cycling between the pre-autophagosomal structure and mitochondria" |
| 4695 | YNL243W | SLA2 SGDID:S000005187, Chr XIV from 188052-190958, Verified ORF, "Transmembrane actin-binding protein involved in membrane cytoskeleton assembly and cell polarization; adaptor protein that links actin to clathrin and endocytosis; present in the actin cortical patch of the emerging bud tip; dimer in vivo" |
| 4696 | YNL244C | SUI1 SGDID:S000005188, Chr XIV from 187497-187171, reverse complement, Verified ORF, "Translation initiation factor eIF1; component of a complex involved in recognition of the initiator codon; modulates translation accuracy at the initiation phase" |
| 4697 | YNL245C | CWC25 SGDID:S000005189, Chr XIV from 186886-186347, reverse complement, Verified ORF, "Component of a complex containing Cef1p, involved in pre-mRNA splicing; has similarity to S. pombe Cwf25p" |
| 4698 | YNL246W | VPS75 SGDID:S000005190, Chr XIV from 185461-185492,185588-186350, Verified ORF, "NAP family histone chaperone; binds to histone H3-H4 tetramers and to histone acetyltransferase RTT109; possesses nucleosome assembly activity in vitro; proposed role in vacuolar protein sorting" |
| 4699 | YNL247W | YNL247W SGDID:S000005191, Chr XIV from 182876-185179, Verified ORF, "Essential protein of unknown function; may interact with ribosomes, based on co-purification experiments" |
| 4700 | YNL248C | RPA49 SGDID:S000005192, Chr XIV from 182609-181362, reverse complement, Verified ORF, "RNA polymerase I subunit A49" |
| 4701 | YNL249C | MPA43 SGDID:S000005193, Chr XIV from 181023-179395, reverse complement, Verified ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 4702 | YNL250W | RAD50 SGDID:S000005194, Chr XIV from 175411-179349, Verified ORF, "Subunit of MRX complex, with Mre11p and Xrs2p, involved in processing double-strand DNA breaks in vegetative cells, initiation of meiotic DSBs, telomere maintenance, and nonhomologous end joining" |
| 4703 | YNL251C | NRD1 SGDID:S000005195, Chr XIV from 174316-172589, reverse complement, Verified ORF, "RNA-binding protein that interacts with the C-terminal domain of the RNA polymerase II large subunit (Rpo21p), required for transcription termination and 3' end maturation of nonpolyadenylated RNAs" |
| 4704 | YNL252C | MRPL17 SGDID:S000005196, Chr XIV from 172287-171442, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 4705 | YNL253W | TEX1 SGDID:S000005197, Chr XIV from 170019-171287, Verified ORF, "Protein involved in mRNA export, component of the transcription export (TREX) complex" |
| 4706 | YNL254C | YNL254C SGDID:S000005198, Chr XIV from 169249-168044, reverse complement, Uncharacterized ORF, "Hypothetical protein; null mutation suppresses cdc13-1 temperature sensitivity" |
| 4707 | YNL255C | GIS2 SGDID:S000005199, Chr XIV from 167791-167330, reverse complement, Verified ORF, "Protein with seven cysteine-rich CCHC zinc-finger motifs, similar to human CNBP, proposed to be involved in the RAS/cAMP signaling pathway" |
| 4708 | YNL256W | FOL1 SGDID:S000005200, Chr XIV from 164624-167098, Verified ORF, "Multifunctional enzyme of the folic acid biosynthesis pathway, has dihydropteroate synthetase, dihydro-6-hydroxymethylpterin pyrophosphokinase, and dihydroneopterin aldolase activities" |
| 4709 | YNL257C | SIP3 SGDID:S000005201, Chr XIV from 164321-160632, reverse complement, Verified ORF, "Protein that activates transcription through interaction with DNA-bound Snf1p, C-terminal region has a putative leucine zipper motif; potential Cdc28p substrate" |
| 4710 | YNL258C | DSL1 SGDID:S000005202, Chr XIV from 160374-158110, reverse complement, Verified ORF, "Peripheral membrane protein required for Golgi-to-ER retrograde traffic; component of the ER target site that interacts with coatomer, the major component of the COPI vesicle protein coat; also interacts with Cin5p and Sec39p" |
| 4711 | YNL259C | ATX1 SGDID:S000005203, Chr XIV from 157866-157645, reverse complement, Verified ORF, "Cytosolic copper metallochaperone that transports copper to the secretory vesicle copper transporter Ccc2p for eventual insertion into Fet3p, which is a multicopper oxidase required for high-affinity iron uptake" |
| 4712 | YNL260C | YNL260C SGDID:S000005204, Chr XIV from 157456-156860, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with similarity to a human protein overexpressed in oral cancers; localizes to the nucleus and cytoplasm; YNL260C is an essential gene" |
| 4713 | YNL261W | ORC5 SGDID:S000005205, Chr XIV from 155101-156540, Verified ORF, "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing" |
| 4714 | YNL262W | POL2 SGDID:S000005206, Chr XIV from 148213-154881, Verified ORF, "Catalytic subunit of DNA polymerase (II) epsilon, one of the major chromosomal DNA replication polymerases characterized by processivity and proofreading exonuclease activity; also involved in DNA synthesis during DNA repair" |
| 4715 | YNL263C | YIF1 SGDID:S000005207, Chr XIV from 147841-146897, reverse complement, Verified ORF, "Integral membrane protein required for the fusion of ER-derived COPII transport vesicles with the Golgi; interacts with Yip1p and Yos1p; localizes to the Golgi, the ER, and COPII vesicles" |
| 4716 | YNL264C | PDR17 SGDID:S000005208, Chr XIV from 146616-145564, reverse complement, Verified ORF, "Phosphatidylinositol transfer protein (PITP), downregulates Plb1p-mediated turnover of phosphatidylcholine, found in the cytosol and microsomes, homologous to Pdr16p, deletion affects phospholipid composition" |
| 4717 | YNL265C | IST1 SGDID:S000005209, Chr XIV from 145282-145256,145150-144281, reverse complement, Verified ORF, "Protein with a positive role in the multivesicular body sorting pathway; functions and forms a complex with Did2p; recruitment to endosomes is mediated by the Vps2p-Vps24p subcomplex of ESCRT-III; also interacts with Vps4p" |
| 4718 | YNL267W | PIK1 SGDID:S000005211, Chr XIV from 140879-144079, Verified ORF, "Phosphatidylinositol 4-kinase; catalyzes first step in the biosynthesis of phosphatidylinositol-4,5-biphosphate; may control cytokineses through the actin cytoskeleton" |
| 4719 | YNL268W | LYP1 SGDID:S000005212, Chr XIV from 138551-140386, Verified ORF, "Lysine permease; one of three amino acid permeases (Alp1p, Can1p, Lyp1p) responsible for uptake of cationic amino acids" |
| 4720 | YNL269W | BSC4 SGDID:S000005213, Chr XIV from 137700-138095, Verified ORF, "Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression; readthrough is increased upon depletion of Sup35p" |
| 4721 | YNL270C | ALP1 SGDID:S000005214, Chr XIV from 137662-135941, reverse complement, Verified ORF, "Arginine transporter; expression is normally very low and it is unclear what conditions would induce significant expression" |
| 4722 | YNL271C | BNI1 SGDID:S000005215, Chr XIV from 135384-129523, reverse complement, Verified ORF, "Formin, nucleates the formation of linear actin filaments, involved in cell processes such as budding and mitotic spindle orientation which require the formation of polarized actin cables, functionally redundant with BNR1" |
| 4723 | YNL272C | SEC2 SGDID:S000005216, Chr XIV from 129084-126805, reverse complement, Verified ORF, "Guanyl-nucleotide exchange factor for the small G-protein Sec4p, located on cytoplasmic vesicles; essential for post-Golgi vesicle transport" |
| 4724 | YNL273W | TOF1 SGDID:S000005217, Chr XIV from 122883-126599, Verified ORF, "Subunit of a replication-pausing checkpoint complex (Tof1p-Mrc1p-Csm3p) that acts at the stalled replication fork to promote sister chromatid cohesion after DNA damage, facilitating gap repair of damaged DNA; interacts with the MCM helicase" |
| 4725 | YNL274C | GOR1 SGDID:S000005218, Chr XIV from 122170-121118, reverse complement, Verified ORF, "Glyoxylate reductase; null mutation results in increased biomass after diauxic shift; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 4726 | YNL275W | BOR1 SGDID:S000005219, Chr XIV from 119268-120998, Verified ORF, "Boron efflux transporter of the plasma membrane; binds HCO3-, I-, Br-, NO3- and Cl-; has similarity to the characterized boron efflux transporter A. thaliana BOR1" |
| 4727 | YNL277W | MET2 SGDID:S000005221, Chr XIV from 117349-118809, Verified ORF, "L-homoserine-O-acetyltransferase, catalyzes the conversion of homoserine to O-acetyl homoserine which is the first step of the methionine biosynthetic pathway" |
| 4728 | YNL277W-A | YNL277W-A SGDID:S000028852, Chr XIV from 116679-116867, Uncharacterized ORF, "Putative protein of unknown function" |
| 4729 | YNL278W | CAF120 SGDID:S000005222, Chr XIV from 113271-116453, Verified ORF, "Part of the evolutionarily-conserved CCR4-NOT transcriptional regulatory complex involved in controlling mRNA initiation, elongation, and degradation" |
| 4730 | YNL279W | PRM1 SGDID:S000005223, Chr XIV from 110917-112902, Verified ORF, "Pheromone-regulated multispanning membrane protein involved in membrane fusion during mating; predicted to have 5 transmembrane segments and a coiled coil domain; localizes to the shmoo tip; regulated by Ste12p" |
| 4731 | YNL280C | ERG24 SGDID:S000005224, Chr XIV from 110411-109095, reverse complement, Verified ORF, "C-14 sterol reductase, acts in ergosterol biosynthesis; mutants accumulate the abnormal sterol ignosterol (ergosta-8,14 dienol), and are viable under anaerobic growth conditions but inviable on rich medium under aerobic conditions" |
| 4732 | YNL281W | HCH1 SGDID:S000005225, Chr XIV from 108467-108928, Verified ORF, "Heat shock protein regulator that binds to Hsp90p and may stimulate ATPase activity; originally identified as a high-copy number suppressor of a HSP90 loss-of-function mutation; GFP-fusion protein localizes to the cytoplasm and nucleus" |
| 4733 | YNL282W | POP3 SGDID:S000005226, Chr XIV from 107687-108274, Verified ORF, "Subunit of both RNase MRP, which cleaves pre-rRNA, and nuclear RNase P, which cleaves tRNA precursors to generate mature 5' ends" |
| 4734 | YNL283C | WSC2 SGDID:S000005227, Chr XIV from 106695-105184, reverse complement, Verified ORF, "Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway involved in maintenance of cell wall integrity and recovery from heat shock; secretory pathway Wsc2p is required for the arrest of secretion response" |
| 4735 | YNL284C | MRPL10 SGDID:S000005228, Chr XIV from 104102-103134, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit; appears as two protein spots (YmL10 and YmL18) on two-dimensional SDS gels" |
| 4736 | YNL284C-A | YNL284C-A SGDID:S000007386, Chr XIV from 102232-100910, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 4737 | YNL284C-B | YNL284C-B SGDID:S000007387, Chr XIV from 102232-100928,100926-96964, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 4738 | YNL286W | CUS2 SGDID:S000005230, Chr XIV from 95223-96080, Verified ORF, "Protein that binds to U2 snRNA and Prp11p, may be involved in U2 snRNA folding; contains two RNA recognition motifs (RRMs)" |
| 4739 | YNL287W | SEC21 SGDID:S000005231, Chr XIV from 91994-94801, Verified ORF, "Gamma subunit of coatomer, a heptameric protein complex that together with Arf1p forms the COPI coat; involved in ER to Golgi transport of selective cargo" |
| 4740 | YNL288W | CAF40 SGDID:S000005232, Chr XIV from 90303-91424, Verified ORF, "Evolutionarily conserved subunit of the CCR4-NOT complex involved in controlling mRNA initiation, elongation and degradation; binds Cdc39p" |
| 4741 | YNL289W | PCL1 SGDID:S000005233, Chr XIV from 87897-88736, Verified ORF, "Pho85 cyclin of the Pcl1,2-like subfamily, involved in entry into the mitotic cell cycle and regulation of morphogenesis, localizes to sites of polarized cell growth" |
| 4742 | YNL290W | RFC3 SGDID:S000005234, Chr XIV from 86218-87240, Verified ORF, "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon" |
| 4743 | YNL291C | MID1 SGDID:S000005235, Chr XIV from 85815-84169, reverse complement, Verified ORF, "N-glycosylated integral membrane protein of the ER membrane and plasma membrane, functions as a stretch-activated Ca2+-permeable cation channel required for Ca2+ influx stimulated by pheromone; interacts with Cch1p; forms an oligomer" |
| 4744 | YNL292W | PUS4 SGDID:S000005236, Chr XIV from 82806-84017, Verified ORF, "Pseudouridine synthase, catalyzes only the formation of pseudouridine-55 (Psi55), a highly conserved tRNA modification, in mitochondrial and cytoplasmic tRNAs; PUS4 overexpression leads to translational derepression of GCN4 (Gcd- phenotype)" |
| 4745 | YNL293W | MSB3 SGDID:S000005237, Chr XIV from 80640-82541, Verified ORF, "GTPase-activating protein for Sec4p and several other Rab GTPases, regulates exocytosis via its action on Sec4p, also required for proper actin organization; similar to Msb4p; both Msb3p and Msb4p localize to sites of polarized growth" |
| 4746 | YNL294C | RIM21 SGDID:S000005238, Chr XIV from 80260-78659, reverse complement, Verified ORF, "Component of the RIM101 pathway, has a role in cell wall construction and alkaline pH response; has similarity to A. nidulans PalH" |
| 4747 | YNL295W | YNL295W SGDID:S000005239, Chr XIV from 76946-78520, Uncharacterized ORF, "Putative protein of unknown function" |
| 4748 | YNL297C | MON2 SGDID:S000005241, Chr XIV from 76583-71673, reverse complement, Verified ORF, "Peripheral membrane protein with a role in endocytosis and vacuole integrity, interacts with Arl1p and localizes to the endosome; member of the Sec7p family of proteins" |
| 4749 | YNL298W | CLA4 SGDID:S000005242, Chr XIV from 68915-71443, Verified ORF, "Cdc42p activated signal transducing kinase of the PAK (p21-activated kinase) family, involved in septin ring assembly and cytokinesis; directly phosphorylates septins Cdc3p and Cdc10p; other yeast PAK family members are Ste20p and Skm1p" |
| 4750 | YNL299W | TRF5 SGDID:S000005243, Chr XIV from 66517-68445, Verified ORF, "Poly (A) polymerase involved in nuclear RNA quality control based on: homology with Trf4p, genetic interactions with TRF4 mutants, physical interaction with Mtr4p (TRAMP subunit), and by direct assay; disputed role as a sigma DNA polymerase" |
| 4751 | YNL300W | YNL300W SGDID:S000005244, Chr XIV from 65744-66052, Uncharacterized ORF, "Glycosylphosphatidylinositol-dependent cell wall protein, expression is periodic and decreases in respone to ergosterol perturbation or upon entry into stationary phase; depletion increases resistance to lactic acid" |
| 4752 | YNL301C | RPL18B SGDID:S000005245, Chr XIV from 64562-64451,64018-63570, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, identical to Rpl18Ap and has similarity to rat L18 ribosomal protein" |
| 4753 | YNL302C | RPS19B SGDID:S000005246, Chr XIV from 62943-62924,62372-61958, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; mutations in human RPS19 are associated with Diamond Blackfan anemia; nearly identical to Rps19Ap" |
| 4754 | YNL304W | YPT11 SGDID:S000005248, Chr XIV from 60297-61550, Verified ORF, "Rab-type small GTPase that interacts with the C-terminal tail domain of Myo2p to mediate distribution of mitochondria to daughter cells" |
| 4755 | YNL305C | YNL305C SGDID:S000005249, Chr XIV from 59791-58898, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YNL305C is not an essential gene" |
| 4756 | YNL306W | MRPS18 SGDID:S000005250, Chr XIV from 58155-58808, Verified ORF, "Mitochondrial ribosomal protein of the small subunit; essential for viability, unlike most other mitoribosomal proteins" |
| 4757 | YNL307C | MCK1 SGDID:S000005251, Chr XIV from 57573-56446, reverse complement, Verified ORF, "Protein serine/threonine/tyrosine (dual-specificity) kinase involved in control of chromosome segregation and in regulating entry into meiosis; related to mammalian glycogen synthase kinases of the GSK-3 family" |
| 4758 | YNL308C | KRI1 SGDID:S000005252, Chr XIV from 55896-54121, reverse complement, Verified ORF, "Essential nucleolar protein required for 40S ribosome biogenesis; physically and functionally interacts with Krr1p" |
| 4759 | YNL309W | STB1 SGDID:S000005253, Chr XIV from 52661-53923, Verified ORF, "Protein with a role in regulation of MBF-specific transcription at Start, phosphorylated by Cln-Cdc28p kinases in vitro; unphosphorylated form binds Swi6p and binding is required for Stb1p function; expression is cell-cycle regulated" |
| 4760 | YNL310C | ZIM17 SGDID:S000005254, Chr XIV from 52430-51906, reverse complement, Verified ORF, "Heat shock protein with a zinc finger motif; essential for protein import into mitochondria; may act with Pam18p to facilitate recognition and folding of imported proteins by Ssc1p (mtHSP70) in the mitochondrial matrix" |
| 4761 | YNL311C | YNL311C SGDID:S000005255, Chr XIV from 51687-49396, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; putative F-box protein; analysis of integrated high-throughput datasets predicts involvement in ubiquitin-dependent protein catabolism" |
| 4762 | YNL312W | RFA2 SGDID:S000005256, Chr XIV from 48286-48292,48401-49215, Verified ORF, "Subunit of heterotrimeric Replication Protein A (RPA), which is a highly conserved single-stranded DNA binding protein involved in DNA replication, repair, and recombination" |
| 4763 | YNL313C | YNL313C SGDID:S000005257, Chr XIV from 48021-45307, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified as interacting with Kar2p, Grs1p, and Tub3p in high-throughput TAP-tagging experiments; YNL313C is an essential gene" |
| 4764 | YNL314W | DAL82 SGDID:S000005258, Chr XIV from 44446-45213, Verified ORF, "Positive regulator of allophanate inducible genes; binds a dodecanucleotide sequence upstream of all genes that are induced by allophanate; contains an UISALL DNA-binding, a transcriptional activation, and a coiled-coil domain" |
| 4765 | YNL315C | ATP11 SGDID:S000005259, Chr XIV from 44279-43323, reverse complement, Verified ORF, "Molecular chaperone, required for the assembly of alpha and beta subunits into the F1 sector of mitochondrial F1F0 ATP synthase" |
| 4766 | YNL316C | PHA2 SGDID:S000005260, Chr XIV from 43074-42070, reverse complement, Verified ORF, "Prephenate dehydratase, catalyzes the conversion of prephanate to phenylpyruvate, which is a step in the phenylalanine biosynthesis pathway" |
| 4767 | YNL317W | PFS2 SGDID:S000005261, Chr XIV from 40618-42015, Verified ORF, "Integral subunit of the pre-mRNA cleavage and polyadenylation factor (CPF) complex; plays an essential role in mRNA 3'-end formation by bridging different processing factors and thereby promoting the assembly of the processing complex" |
| 4768 | YNL318C | HXT14 SGDID:S000005262, Chr XIV from 40328-38706, reverse complement, Verified ORF, "Protein with similarity to hexose transporter family members, expression is induced in low glucose and repressed in high glucose; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 4769 | YNL320W | YNL320W SGDID:S000005264, Chr XIV from 37699-38553, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 4770 | YNL321W | VNX1 SGDID:S000005265, Chr XIV from 34695-37421, Verified ORF, "Low affinity vacuolar membrane localized monovalent cation/H+ antiporter; member of the calcium exchanger (CAX) family; potential Cdc28p substrate" |
| 4771 | YNL322C | KRE1 SGDID:S000005266, Chr XIV from 34234-33293, reverse complement, Verified ORF, "Cell wall glycoprotein involved in beta-glucan assembly; serves as a K1 killer toxin membrane receptor" |
| 4772 | YNL323W | LEM3 SGDID:S000005267, Chr XIV from 31943-33187, Verified ORF, "Membrane protein of the plasma membrane and ER, involved in translocation of phospholipids and alkylphosphocholine drugs across the plasma membrane" |
| 4773 | YNL325C | FIG4 SGDID:S000005269, Chr XIV from 31377-28738, reverse complement, Verified ORF, "Polyphosphatidylinositol phosphatase involved in the metabolism of phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2); required for efficient mating; physically associates with and regulated by Vac14p; contains a SAC1-like domain" |
| 4774 | YNL326C | PFA3 SGDID:S000005270, Chr XIV from 28346-27336, reverse complement, Verified ORF, "Palmitoyltransferase for Vac8p, required for vacuolar membrane fusion; contains an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; autoacylates; required for vacuolar integrity under stress conditions" |
| 4775 | YNL327W | EGT2 SGDID:S000005271, Chr XIV from 24047-27172, Verified ORF, "Glycosylphosphatidylinositol (GPI)-anchored cell wall endoglucanase required for proper cell separation after cytokinesis, expression is activated by Swi5p and tightly regulated in a cell cycle-dependent manner" |
| 4776 | YNL328C | MDJ2 SGDID:S000005272, Chr XIV from 23274-22834, reverse complement, Verified ORF, "Constituent of the mitochondrial import motor associated with the presequence translocase; function overlaps with that of Pam18p; stimulates the ATPase activity of Ssc1p to drive mitochondrial import; contains a J domain" |
| 4777 | YNL329C | PEX6 SGDID:S000005273, Chr XIV from 22633-19541, reverse complement, Verified ORF, "AAA-peroxin that heterodimerizes with AAA-peroxin Pex1p and participates in the recycling of peroxisomal signal receptor Pex5p from the peroxisomal membrane to the cystosol" |
| 4778 | YNL330C | RPD3 SGDID:S000005274, Chr XIV from 19302-18001, reverse complement, Verified ORF, "Histone deacetylase; regulates transcription and silencing; plays a role in regulating Ty1 transposition" |
| 4779 | YNL331C | AAD14 SGDID:S000005275, Chr XIV from 17248-16118, reverse complement, Verified ORF, "Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role" |
| 4780 | YNL332W | THI12 SGDID:S000005276, Chr XIV from 14832-15854, Verified ORF, "Protein involved in synthesis of the thiamine precursor hydroxymethylpyrimidine (HMP); member of a subtelomeric gene family including THI5, THI11, THI12, and THI13" |
| 4781 | YNL333W | SNZ2 SGDID:S000005277, Chr XIV from 13267-14163, Verified ORF, "Member of a stationary phase-induced gene family; transcription of SNZ2 is induced prior to diauxic shift, and also in the absence of thiamin in a Thi2p-dependent manner; forms a coregulated gene pair with SNO2; interacts with Thi11p" |
| 4782 | YNL334C | SNO2 SGDID:S000005278, Chr XIV from 12876-12208, reverse complement, Verified ORF, "Protein of unknown function, nearly identical to Sno3p; expression is induced before the diauxic shift and also in the absence of thiamin" |
| 4783 | YNL335W | YNL335W SGDID:S000005279, Chr XIV from 11452-12129, Uncharacterized ORF, "Hypothetical protein" |
| 4784 | YNL336W | COS1 SGDID:S000005280, Chr XIV from 8330-9475, Verified ORF, "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" |
| 4785 | YNL339C | YRF1-6 SGDID:S000005283, Chr XIV from 6098-6080,5931-371, reverse complement, Verified ORF, "Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p" |
| 4786 | YNR001C | CIT1 SGDID:S000005284, Chr XIV from 631063-629624, reverse complement, Verified ORF, "Citrate synthase, catalyzes the condensation of acetyl coenzyme A and oxaloacetate to form citrate; the rate-limiting enzyme of the TCA cycle; nuclear encoded mitochondrial protein" |
| 4787 | YNR002C | ATO2 SGDID:S000005285, Chr XIV from 633858-633010, reverse complement, Verified ORF, "Putative transmembrane protein involved in export of ammonia, a starvation signal that promotes cell death in aging colonies; phosphorylated in mitochondria; member of the TC 9.B.33 YaaH family; homolog of Ady2p and Y. lipolytica Gpr1p" |
| 4788 | YNR003C | RPC34 SGDID:S000005286, Chr XIV from 635299-634346, reverse complement, Verified ORF, "RNA polymerase III subunit C34; interacts with TFIIIB70 and is a key determinant in pol III recruitment by the preinitiation complex" |
| 4789 | YNR004W | YNR004W SGDID:S000005287, Chr XIV from 635945-636385, Uncharacterized ORF, "Putative protein of unknown function; haploid disruptant exhibits slow growth rate on glucose-minimal medium at 15 C" |
| 4790 | YNR006W | VPS27 SGDID:S000005289, Chr XIV from 636988-638856, Verified ORF, "Endosomal protein that forms a complex with Hse1p; required for recycling Golgi proteins, forming lumenal membranes and sorting ubiquitinated proteins destined for degradation; has Ubiquitin Interaction Motifs which bind ubiquitin (Ubi4p)" |
| 4791 | YNR007C | ATG3 SGDID:S000005290, Chr XIV from 640116-639184, reverse complement, Verified ORF, "E2-like enzyme involved in autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; plays a role in formation of Atg8p-phosphatidylethanolamine conjugates, which are involved in membrane dynamics during autophagy and Cvt" |
| 4792 | YNR008W | LRO1 SGDID:S000005291, Chr XIV from 640398-642383, Verified ORF, "Acyltransferase that catalyzes diacylglycerol esterification; one of several acyltransferases that contribute to triglyceride synthesis; putative homolog of human lecithin cholesterol acyltransferase" |
| 4793 | YNR009W | NRM1 SGDID:S000005292, Chr XIV from 642692-643441, Verified ORF, "Transcriptional co-repressor of MBF (MCB binding factor)-regulated gene expression; Nrm1p associates stably with promoters via MBF to repress transcription upon exit from G1 phase" |
| 4794 | YNR010W | CSE2 SGDID:S000005293, Chr XIV from 643746-644195, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; component of the Med9/10 module; required for regulation of RNA polymerase II activity" |
| 4795 | YNR011C | PRP2 SGDID:S000005294, Chr XIV from 646952-644322, reverse complement, Verified ORF, "RNA-dependent ATPase in the DEAH-box family, required for activation of the spliceosome before the first transesterification step in RNA splicing" |
| 4796 | YNR012W | URK1 SGDID:S000005295, Chr XIV from 647434-648939, Verified ORF, "Uridine/cytidine kinase, component of the pyrimidine ribonucleotide salvage pathway that converts uridine into UMP and cytidine into CMP; involved in the pyrimidine deoxyribonucleotide salvage pathway, converting deoxycytidine into dCMP" |
| 4797 | YNR013C | PHO91 SGDID:S000005296, Chr XIV from 651714-649030, reverse complement, Verified ORF, "Low-affinity phosphate transporter of the vacuolar membrane; deletion of pho84, pho87, pho89, pho90, and pho91 causes synthetic lethality; transcription independent of Pi and Pho4p activity; overexpression results in vigorous growth" |
| 4798 | YNR014W | YNR014W SGDID:S000005297, Chr XIV from 652467-653105, Uncharacterized ORF, "Putative protein of unknown function; expression is cell-cycle regulated, Azf1p-dependent, and heat-inducible" |
| 4799 | YNR015W | SMM1 SGDID:S000005298, Chr XIV from 653389-654543, Verified ORF, "Dihydrouridine synthase, member of a family of dihydrouridine synthases including Dus1p, Smm1p, Dus3p, and Dus4p; modifies uridine residues at position 20 of cytoplasmic tRNAs" |
| 4800 | YNR016C | ACC1 SGDID:S000005299, Chr XIV from 661376-654675, reverse complement, Verified ORF, "Acetyl-CoA carboxylase, biotin containing enzyme that catalyzes the carboxylation of acetyl-CoA to form malonyl-CoA; required for de novo biosynthesis of long-chain fatty acids" |
| 4801 | YNR017W | TIM23 SGDID:S000005300, Chr XIV from 662915-663583, Verified ORF, "Essential protein of the mitochondrial inner membrane, component of the mitochondrial import system" |
| 4802 | YNR018W | YNR018W SGDID:S000005301, Chr XIV from 664272-664946, Uncharacterized ORF, "Putative protein of unknown function; non-tagged protein is detected in purified mitochondria; null mutant displays decreased frequency of mitochondrial genome loss (petite formation) and severe growth defect in minimal glycerol media" |
| 4803 | YNR019W | ARE2 SGDID:S000005302, Chr XIV from 665341-667269, Verified ORF, "Acyl-CoA:sterol acyltransferase, isozyme of Are1p; endoplasmic reticulum enzyme that contributes the major sterol esterification activity in the presence of oxygen" |
| 4804 | YNR020C | ATP23 SGDID:S000005303, Chr XIV from 668224-667412, reverse complement, Verified ORF, "Putative metalloprotease of the mitochondrial inner membrane, required for processing of Atp6p; has an additional role in assembly of the F0 sector of the F1F0 ATP synthase complex" |
| 4805 | YNR021W | YNR021W SGDID:S000005304, Chr XIV from 668379-669593, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YNR021W is not an essential gene" |
| 4806 | YNR022C | MRPL50 SGDID:S000005305, Chr XIV from 670195-669776, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the large subunit, not essential for mitochondrial translation" |
| 4807 | YNR023W | SNF12 SGDID:S000005306, Chr XIV from 670420-672120, Verified ORF, "73 kDa subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; homolog of Rsc6p subunit of the RSC chromatin remodeling complex; deletion mutants are temperature-sensitive" |
| 4808 | YNR024W | YNR024W SGDID:S000005307, Chr XIV from 672411-672971, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the nucleus" |
| 4809 | YNR026C | SEC12 SGDID:S000005309, Chr XIV from 674691-673276, reverse complement, Verified ORF, "Guanine nucleotide exchange factor (GEF); glycosylated integral membrane protein of the endoplasmic reticulum, important for the initiation of transport vesicle budding from the endoplasmic reticulum through activation of the GTPase Sar1p" |
| 4810 | YNR027W | BUD17 SGDID:S000005310, Chr XIV from 674925-675878, Verified ORF, "Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern" |
| 4811 | YNR028W | CPR8 SGDID:S000005311, Chr XIV from 676179-677105, Verified ORF, "Peptidyl-prolyl cis-trans isomerase (cyclophilin), catalyzes the cis-trans isomerization of peptide bonds N-terminal to proline residues; similarity to Cpr4p suggests a potential role in the secretory pathway" |
| 4812 | YNR029C | YNR029C SGDID:S000005312, Chr XIV from 678490-677201, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, deletion confers reduced fitness in saline" |
| 4813 | YNR030W | ALG12 SGDID:S000005313, Chr XIV from 678801-680456, Verified ORF, "Alpha-1,6-mannosyltransferase localized to the ER; responsible for the addition of the alpha-1,6 mannose to dolichol-linked Man7GlcNAc2, acts in the dolichol pathway for N-glycosylation" |
| 4814 | YNR031C | SSK2 SGDID:S000005314, Chr XIV from 685435-680696, reverse complement, Verified ORF, "MAP kinase kinase kinase of the HOG1 mitogen-activated signaling pathway; interacts with Ssk1p, leading to autophosphorylation and activation of Ssk2p which phosphorylates Pbs2p; also mediates actin cytoskeleton recovery from osmotic stress" |
| 4815 | YNR032C-A | HUB1 SGDID:S000007251, Chr XIV from 687466-687245, reverse complement, Verified ORF, "Ubiquitin-like protein modifier, may function in modification of Sph1p and Hbt1p, functionally complemented by the human or S. pombe ortholog; mechanism of Hub1p adduct formation not yet clear" |
| 4816 | YNR032W | PPG1 SGDID:S000005315, Chr XIV from 686012-687118, Verified ORF, "Putative serine/threonine protein phosphatase, required for glycogen accumulation; interacts with Tap42p, which binds to and regulates other protein phosphatases" |
| 4817 | YNR033W | ABZ1 SGDID:S000005316, Chr XIV from 687637-690000, Verified ORF, "Para-aminobenzoate (PABA) synthase, has similarity to Escherichia coli PABA synthase components PabA and PabB" |
| 4818 | YNR034W | SOL1 SGDID:S000005317, Chr XIV from 690323-691288, Verified ORF, "Protein with a possible role in tRNA export; shows similarity to 6-phosphogluconolactonase non-catalytic domains but does not exhibit this enzymatic activity; homologous to Sol2p, Sol3p, and Sol4p" |
| 4819 | YNR034W-A | YNR034W-A SGDID:S000007525, Chr XIV from 692563-692859, Uncharacterized ORF, "Putative protein of unknown function; expression is regulated by Msn2p/Msn4p" |
| 4820 | YNR035C | ARC35 SGDID:S000005318, Chr XIV from 694049-693021, reverse complement, Verified ORF, "Subunit of the ARP2/3 complex, which is required for the motility and integrity of cortical actin patches; required for cortical localization of calmodulin" |
| 4821 | YNR036C | YNR036C SGDID:S000005319, Chr XIV from 694824-694363, reverse complement, Verified ORF, "Mitochondrial protein; may interact with ribosomes based on co-purification experiments; similar to E. coli and human mitochondrial S12 ribosomal proteins" |
| 4822 | YNR037C | RSM19 SGDID:S000005320, Chr XIV from 695329-695054, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the small subunit, has similarity to E. coli S19 ribosomal protein" |
| 4823 | YNR038W | DBP6 SGDID:S000005321, Chr XIV from 695597-697486, Verified ORF, "Essential protein involved in ribosome biogenesis; putative ATP-dependent RNA helicase of the DEAD-box protein family" |
| 4824 | YNR039C | ZRG17 SGDID:S000005322, Chr XIV from 699433-697616, reverse complement, Verified ORF, "Endoplasmic reticulum protein of unknown function, transcription is induced under conditions of zinc deficiency; mutant phenotype suggests a role in uptake of zinc" |
| 4825 | YNR040W | YNR040W SGDID:S000005323, Chr XIV from 699692-700462, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 4826 | YNR041C | COQ2 SGDID:S000005324, Chr XIV from 701661-700543, reverse complement, Verified ORF, "Para hydroxybenzoate: polyprenyl transferase, catalyzes the second step in ubiquinone (coenzyme Q) biosynthesis" |
| 4827 | YNR043W | MVD1 SGDID:S000005326, Chr XIV from 701897-703087, Verified ORF, "Mevalonate pyrophosphate decarboxylase, essential enzyme involved in the biosynthesis of isoprenoids and sterols, including ergosterol; acts as a homodimer" |
| 4828 | YNR044W | AGA1 SGDID:S000005327, Chr XIV from 703701-705878, Verified ORF, "Anchorage subunit of a-agglutinin of a-cells, highly O-glycosylated protein with N-terminal secretion signal and C-terminal signal for addition of GPI anchor to cell wall, linked to adhesion subunit Aga2p via two disulfide bonds" |
| 4829 | YNR045W | PET494 SGDID:S000005328, Chr XIV from 706141-707610, Verified ORF, "Mitochondrial translational activator specific for the COX3 mRNA, acts together with Pet54p and Pet122p; located in the mitochondrial inner membrane" |
| 4830 | YNR046W | TRM112 SGDID:S000005329, Chr XIV from 707790-708197, Verified ORF, "Subunit of an adoMet-dependent tRNA methyltransferase (MTase) complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; putative zinc binding subunit of other MTase-related proteins" |
| 4831 | YNR047W | YNR047W SGDID:S000005330, Chr XIV from 708525-711206, Uncharacterized ORF, "Putative protein kinase that, when overexpressed, interferes with pheromone-induced growth arrest; localizes to the cytoplasm; potential Cdc28p substrate" |
| 4832 | YNR048W | YNR048W SGDID:S000005331, Chr XIV from 711632-712813, Verified ORF, "Protein proposed to interact with phospholipid translocases, shares similarity to Cdc50p" |
| 4833 | YNR049C | MSO1 SGDID:S000005332, Chr XIV from 713657-713025, reverse complement, Verified ORF, "Probable component of the secretory vesicle docking complex, acts at a late step in secretion; shows genetic and physical interactions with Sec1p and is enriched in microsomal membrane fractions; required for sporulation" |
| 4834 | YNR050C | LYS9 SGDID:S000005333, Chr XIV from 715390-714050, reverse complement, Verified ORF, "Saccharopine dehydrogenase (NADP+, L-glutamate-forming); catalyzes the formation of saccharopine from alpha-aminoadipate 6-semialdehyde, which is the seventh step in lysine biosynthesis pathway" |
| 4835 | YNR051C | BRE5 SGDID:S000005334, Chr XIV from 718329-716782, reverse complement, Verified ORF, "Ubiquitin protease cofactor, forms deubiquitination complex with Ubp3p that coregulates anterograde and retrograde transport between the endoplasmic reticulum and Golgi compartments; null is sensitive to brefeldin A" |
| 4836 | YNR052C | POP2 SGDID:S000005335, Chr XIV from 720649-719348, reverse complement, Verified ORF, "RNase of the DEDD superfamily, subunit of the Ccr4-Not complex that mediates 3' to 5' mRNA deadenylation" |
| 4837 | YNR053C | NOG2 SGDID:S000005336, Chr XIV from 723113-722304,721772-721122, reverse complement, Verified ORF, "Putative GTPase that associates with pre-60S ribosomal subunits in the nucleolus and is required for their nuclear export and maturation" |
| 4838 | YNR054C | ESF2 SGDID:S000005337, Chr XIV from 724307-723357, reverse complement, Verified ORF, "Essential nucleolar protein involved in pre-18S rRNA processing; binds to RNA and stimulates ATPase activity of Dbp8; involved in assembly of the small subunit (SSU) processome" |
| 4839 | YNR055C | HOL1 SGDID:S000005338, Chr XIV from 730187-728427, reverse complement, Verified ORF, "Putative transporter in the major facilitator superfamily (DHA1 family) of multidrug resistance transporters; mutations in membrane-spanning domains permit cation and histidinol uptake" |
| 4840 | YNR056C | BIO5 SGDID:S000005339, Chr XIV from 733303-731618, reverse complement, Verified ORF, "Putative transmembrane protein involved in the biotin biosynthesis pathway; responsible for uptake of 7-keto 8-aminopelargonic acid; BIO5 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis" |
| 4841 | YNR057C | BIO4 SGDID:S000005340, Chr XIV from 734069-733356, reverse complement, Verified ORF, "Dethiobiotin synthetase, catalyzes the third step in the biotin biosynthesis pathway; BIO4 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis; expression appears to be repressed at low iron levels" |
| 4842 | YNR058W | BIO3 SGDID:S000005341, Chr XIV from 734291-735733, Verified ORF, "7,8-diamino-pelargonic acid aminotransferase (DAPA), catalyzes the second step in the biotin biosynthesis pathway; BIO3 is in a cluster of 3 genes (BIO3, BIO4, and BIO5) that mediate biotin synthesis" |
| 4843 | YNR059W | MNT4 SGDID:S000005342, Chr XIV from 736803-738545, Verified ORF, "Putative alpha-1,3-mannosyltransferase, not required for protein O-glycosylation" |
| 4844 | YNR060W | FRE4 SGDID:S000005343, Chr XIV from 739951-742110, Verified ORF, "Ferric reductase, reduces a specific subset of siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels" |
| 4845 | YNR061C | YNR061C SGDID:S000005344, Chr XIV from 743540-742881, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 4846 | YNR062C | YNR062C SGDID:S000005345, Chr XIV from 745343-744360, reverse complement, Uncharacterized ORF, "Putative membrane protein of unknown function" |
| 4847 | YNR063W | YNR063W SGDID:S000005346, Chr XIV from 746943-748766, Uncharacterized ORF, "Putative zinc-cluster protein of unknown function" |
| 4848 | YNR064C | YNR064C SGDID:S000005347, Chr XIV from 750008-749136, reverse complement, Verified ORF, "Epoxide hydrolase, member of the alpha/beta hydrolase fold family; may have a role in detoxification of epoxides" |
| 4849 | YNR065C | YNR065C SGDID:S000005348, Chr XIV from 753700-750350, reverse complement, Uncharacterized ORF, "Protein of unknown function; protein-protein interactions suggest a possible role in actin patch formation; YNR065C is not an essential gene" |
| 4850 | YNR066C | YNR066C SGDID:S000005349, Chr XIV from 755035-753725, reverse complement, Uncharacterized ORF, "Putative membrane-localized protein of unknown function" |
| 4851 | YNR067C | DSE4 SGDID:S000005350, Chr XIV from 759099-755746, reverse complement, Verified ORF, "Daughter cell-specific secreted protein with similarity to glucanases, degrades cell wall from the daughter side causing daughter to separate from mother" |
| 4852 | YNR068C | YNR068C SGDID:S000005351, Chr XIV from 760885-760067, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 4853 | YNR069C | BSC5 SGDID:S000005352, Chr XIV from 762592-761123, reverse complement, Verified ORF, "Protein of unknown function, ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression" |
| 4854 | YNR070W | YNR070W SGDID:S000005353, Chr XIV from 765375-769376, Uncharacterized ORF, "Putative transporter of the ATP-binding cassette (ABC) family, implicated in pleiotropic drug resistance; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 4855 | YNR071C | YNR071C SGDID:S000005354, Chr XIV from 771468-770440, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 4856 | YNR072W | HXT17 SGDID:S000005355, Chr XIV from 772657-774351, Verified ORF, "Hexose transporter, up-regulated in media containing raffinose and galactose at pH 7.7 versus pH 4.7, repressed by high levels of glucose" |
| 4857 | YNR073C | YNR073C SGDID:S000005356, Chr XIV from 776300-774792, reverse complement, Uncharacterized ORF, "Putative mannitol dehydrogenase" |
| 4858 | YNR074C | AIF1 SGDID:S000005357, Chr XIV from 778738-777602, reverse complement, Verified ORF, "Mitochondrial cell death effector that translocates to the nucleus in response to apoptotic stimuli, homolog of mammalian Apoptosis-Inducing Factor, putative reductase" |
| 4859 | YNR075C-A | YNR075C-A SGDID:S000028706, Chr XIV from 781603-781511, reverse complement, Uncharacterized ORF, "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 4860 | YNR075W | COS10 SGDID:S000005358, Chr XIV from 779916-781040, Verified ORF, "Protein of unknown function, member of the DUP380 subfamily of conserved, often subtelomerically-encoded proteins" |
| 4861 | YNR076W | PAU6 SGDID:S000005359, Chr XIV from 781918-782280, Verified ORF, "Part of 23-member seripauperin multigene family encoded mainly in subtelomeric regions, active during alcoholic fermentation, regulated by anaerobiosis, negatively regulated by oxygen, repressed by heme" |
| 4862 | YOL001W | PHO80 SGDID:S000005361, Chr XV from 325250-326131, Verified ORF, "Cyclin, negatively regulates phosphate metabolism; Pho80p-Pho85p (cyclin-CDK complex) phosphorylates Pho4p and Swi5p; deletion of PHO80 leads to aminoglycoside supersensitivity; truncated form of PHO80 affects vacuole inheritance" |
| 4863 | YOL002C | IZH2 SGDID:S000005362, Chr XV from 324365-323412, reverse complement, Verified ORF, "Plasma membrane protein involved in zinc metabolism and osmotin-induced apoptosis; transcription regulated by Zap1p, zinc and fatty acid levels; similar to mammalian adiponectins; deletion increases sensitivity to elevated zinc" |
| 4864 | YOL003C | PFA4 SGDID:S000005363, Chr XV from 322995-321859, reverse complement, Verified ORF, "Palmitoyltransferase with autoacylation activity, required for palmitoylation of amino acid permeases containing a C-terminal Phe-Trp-Cys site; required for modification of Chs3p; member of the DHHC family of putative palmitoyltransferases" |
| 4865 | YOL004W | SIN3 SGDID:S000005364, Chr XV from 316939-321549, Verified ORF, "Component of the Sin3p-Rpd3p histone deacetylase complex, involved in transcriptional repression and activation of diverse processes, including mating-type switching and meiosis; involved in the maintenance of chromosomal integrity" |
| 4866 | YOL005C | RPB11 SGDID:S000005365, Chr XV from 316176-315814, reverse complement, Verified ORF, "RNA polymerase II subunit B12.5; part of central core; similar to Rpc19p and bacterial alpha subunit" |
| 4867 | YOL006C | TOP1 SGDID:S000005366, Chr XV from 315388-313079, reverse complement, Verified ORF, "Topoisomerase I, nuclear enzyme that relieves torsional strain in DNA by cleaving and re-sealing the phosphodiester backbone; relaxes both positively and negatively supercoiled DNA; functions in replication, transcription, and recombination" |
| 4868 | YOL007C | CSI2 SGDID:S000005367, Chr XV from 312368-311343, reverse complement, Verified ORF, "Protein of unknown function; green fluorescent protein (GFP)- fusion protein localizes to the mother side of the bud neck and the vacuole; YOL007C is not an essential gene" |
| 4869 | YOL008W | COQ10 SGDID:S000005368, Chr XV from 310313-310936, Verified ORF, "Coenzyme Q (ubiquinone) binding protein, functions in the delivery of Q6 to its proper location for electron transport during respiration; START domain protein with homologs in bacteria and eukaryotes" |
| 4870 | YOL009C | MDM12 SGDID:S000005369, Chr XV from 310140-309325, reverse complement, Verified ORF, "Mitochondrial outer membrane protein, required for transmission of mitochondria to daughter cells; component of the Mdm10-Mdm12-Mmm1 complex involved in import and assembly of outer membrane beta-barrel proteins" |
| 4871 | YOL010W | RCL1 SGDID:S000005370, Chr XV from 307939-309042, Verified ORF, "RNA terminal phosphate cyclase-like protein involved in rRNA processing at sites A0, A1, and A2; does not possess detectable RNA cyclase activity" |
| 4872 | YOL011W | PLB3 SGDID:S000005371, Chr XV from 305350-307410, Verified ORF, "Phospholipase B (lysophospholipase) involved in phospholipid metabolism; hydrolyzes phosphatidylinositol and phosphatidylserine and displays transacylase activity in vitro" |
| 4873 | YOL012C | HTZ1 SGDID:S000005372, Chr XV from 303984-303580, reverse complement, Verified ORF, "Histone variant H2AZ, exchanged for histone H2A in nucleosomes by the SWR1 complex; involved in transcriptional regulation through prevention of the spread of silent heterochromatin" |
| 4874 | YOL013C | HRD1 SGDID:S000005373, Chr XV from 303036-301381, reverse complement, Verified ORF, "Ubiquitin-protein ligase required for endoplasmic reticulum-associated degradation (ERAD) of misfolded proteins; genetically linked to the unfolded protein response (UPR); regulated through association with Hrd3p; contains an H2 ring finger" |
| 4875 | YOL013W-A | YOL013W-A SGDID:S000028811, Chr XV from 301048-301239, Uncharacterized ORF, "Putative protein of unknown function; identified by SAGE" |
| 4876 | YOL014W | YOL014W SGDID:S000005374, Chr XV from 299694-300068, Uncharacterized ORF, "Putative protein of unknown function" |
| 4877 | YOL015W | IRC10 SGDID:S000005375, Chr XV from 297079-298839, Verified ORF, "Putative protein of unknown function; null mutant displays increased levels of spontaneous Rad52p foci" |
| 4878 | YOL016C | CMK2 SGDID:S000005376, Chr XV from 296121-294778, reverse complement, Verified ORF, "Calmodulin-dependent protein kinase; may play a role in stress response, many CA++/calmodulan dependent phosphorylation substrates demonstrated in vitro, amino acid sequence similar to Cmk1p and mammalian Cam Kinase II" |
| 4879 | YOL017W | ESC8 SGDID:S000005377, Chr XV from 292530-294674, Verified ORF, "Protein involved in telomeric and mating-type locus silencing, interacts with Sir2p and also interacts with the Gal11p, which is a component of the RNA pol II mediator complex" |
| 4880 | YOL018C | TLG2 SGDID:S000005378, Chr XV from 292075-290882, reverse complement, Verified ORF, "Syntaxin-like t-SNARE that forms a complex with Tlg1p and Vti1p and mediates fusion of endosome-derived vesicles with the late Golgi; binds Vps45p, which prevents Tlg2p degradation and also facilitates t-SNARE complex formation" |
| 4881 | YOL019W | YOL019W SGDID:S000005379, Chr XV from 288899-290554, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole" |
| 4882 | YOL019W-A | YOL019W-A SGDID:S000028707, Chr XV from 288421-288573, Uncharacterized ORF, "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 4883 | YOL020W | TAT2 SGDID:S000005380, Chr XV from 286173-287951, Verified ORF, "High affinity tryptophan and tyrosine permease, overexpression confers FK506 and FTY720 resistance" |
| 4884 | YOL021C | DIS3 SGDID:S000005381, Chr XV from 285427-282422, reverse complement, Verified ORF, "Catalytic component of the exosome, involved in RNA processing and degradation; binds Gsp1p/Ran and enhances the GEF activity of Srm1p; implicated in mitotic control; homologous to the E. coli RNase R of the RNase II family" |
| 4885 | YOL022C | YOL022C SGDID:S000005382, Chr XV from 281499-280273, reverse complement, Uncharacterized ORF, "Cytoplasmic protein of unknown function; essential gene in S288C, and non-essential with reduced growth rate in CEN.PK2; Null mutant accumulates 20S pre-rRNA" |
| 4886 | YOL023W | IFM1 SGDID:S000005383, Chr XV from 278057-280087, Verified ORF, "Mitochondrial translation initiation factor 2" |
| 4887 | YOL024W | YOL024W SGDID:S000005384, Chr XV from 277087-277605, Uncharacterized ORF, "Putative protein of unknown function, predicted to have thiol-disulfide oxidoreductase active site" |
| 4888 | YOL025W | LAG2 SGDID:S000005385, Chr XV from 274958-276940, Verified ORF, "Protein involved in determination of longevity; LAG2 gene is preferentially expressed in young cells; overexpression extends the mean and maximum life span of cells" |
| 4889 | YOL026C | MIM1 SGDID:S000005386, Chr XV from 274354-274013, reverse complement, Verified ORF, "Mitochondrial outer membrane protein, required for assembly of the translocase of the outer membrane (TOM) complex and thereby for mitochondrial protein import; N terminus is exposed to the cytosol: transmembrane segment is highly conserved" |
| 4890 | YOL027C | MDM38 SGDID:S000005387, Chr XV from 273725-272004, reverse complement, Verified ORF, "Mitochondrial inner membrane protein, involved in membrane integration of a subset of mitochondrial proteins; required for K+/H+ exchange; associates with mitochondrial ribosomes; human ortholog Letm1 implicated in Wolf-Hirschhorn syndrome" |
| 4891 | YOL028C | YAP7 SGDID:S000005388, Chr XV from 271371-270634, reverse complement, Verified ORF, "Putative basic leucine zipper (bZIP) transcription factor" |
| 4892 | YOL029C | YOL029C SGDID:S000005389, Chr XV from 270421-269816, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified as interacting with Hsc82p and Hsp82p in high-throughput two-hybrid screens" |
| 4893 | YOL030W | GAS5 SGDID:S000005390, Chr XV from 268188-269642, Verified ORF, "1,3-beta-glucanosyltransferase, has similarity to Gas1p; localizes to the cell wall" |
| 4894 | YOL031C | SIL1 SGDID:S000005391, Chr XV from 267530-266265, reverse complement, Verified ORF, "Nucleotide exchange factor for the endoplasmic reticulum (ER) lumenal Hsp70 chaperone Kar2p, required for protein translocation into the ER; homolog of Yarrowia lipolytica SLS1; GrpE-like protein" |
| 4895 | YOL032W | OPI10 SGDID:S000005392, Chr XV from 265430-266170, Verified ORF, "Protein with a possible role in phospholipid biosynthesis, based on inositol-excreting phenotype of the null mutant and its suppression by exogenous choline" |
| 4896 | YOL033W | MSE1 SGDID:S000005393, Chr XV from 263476-265086, Verified ORF, "Mitochondrial glutamyl-tRNA synthetase, encoded by a nuclear gene" |
| 4897 | YOL034W | SMC5 SGDID:S000005394, Chr XV from 259924-263205, Verified ORF, "Structural maintenance of chromosomes (SMC) protein; essential subunit of the Mms21-Smc5-Smc6 complex; required for growth and DNA repair; S. pombe homolog forms a heterodimer with S. pombe Rad18p that is involved in DNA repair" |
| 4898 | YOL036W | YOL036W SGDID:S000005396, Chr XV from 256744-259029, Uncharacterized ORF, "Protein of unknown function; potential Cdc28p substrate" |
| 4899 | YOL038C-A | YOL038C-A SGDID:S000028812, Chr XV from 255020-254925, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by SAGE analysis" |
| 4900 | YOL038W | PRE6 SGDID:S000005398, Chr XV from 255336-256100, Verified ORF, "Alpha 4 subunit of the 20S proteasome; may replace alpha 3 subunit (Pre9p) under stress conditions to create a more active proteasomal isoform; GFP-fusion protein relocates from cytosol to the mitochondrial surface upon oxidative stress" |
| 4901 | YOL039W | RPP2A SGDID:S000005399, Chr XV from 254296-254616, Verified ORF, "Ribosomal protein P2 alpha, a component of the ribosomal stalk, which is involved in the interaction between translational elongation factors and the ribosome; regulates the accumulation of P1 (Rpp1Ap and Rpp1Bp) in the cytoplasm" |
| 4902 | YOL040C | RPS15 SGDID:S000005400, Chr XV from 253576-253148, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; has similarity to E. coli S19 and rat S15 ribosomal proteins" |
| 4903 | YOL041C | NOP12 SGDID:S000005401, Chr XV from 252645-251266, reverse complement, Verified ORF, "Nucleolar protein, required for pre-25S rRNA processing; contains an RNA recognition motif (RRM) and has similarity to Nop13p, Nsr1p, and putative orthologs in Drosophila and S. pombe" |
| 4904 | YOL042W | NGL1 SGDID:S000005402, Chr XV from 249824-250915, Verified ORF, "Putative endonuclease, has a domain similar to a magnesium-dependent endonuclease motif in mRNA deadenylase Ccr4p; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 4905 | YOL043C | NTG2 SGDID:S000005403, Chr XV from 249533-248391, reverse complement, Verified ORF, "DNA N-glycosylase and apurinic/apyrimidinic (AP) lyase involved in base excision repair, localizes to the nucleus" |
| 4906 | YOL044W | PEX15 SGDID:S000005404, Chr XV from 247149-248300, Verified ORF, "Phosphorylated tail-anchored type II integral peroxisomal membrane protein required for peroxisome biogenesis, cells lacking Pex15p mislocalize peroxisomal matrix proteins to cytosol, overexpression results in impaired peroxisome assembly" |
| 4907 | YOL045W | PSK2 SGDID:S000005405, Chr XV from 243496-246801, Verified ORF, "One of two (see also PSK1) PAS domain containing S/T protein kinases; regulates sugar flux and translation in response to an unknown metabolite by phosphorylating Ugp1p and Gsy2p (sugar flux) and Caf20p, Tif11p and Sro9p (translation)" |
| 4908 | YOL047C | YOL047C SGDID:S000005407, Chr XV from 242746-242504,242440-241613, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 4909 | YOL048C | YOL048C SGDID:S000005408, Chr XV from 241309-241025,240946-240203, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 4910 | YOL049W | GSH2 SGDID:S000005409, Chr XV from 238618-240093, Verified ORF, "Glutathione synthetase, catalyzes the ATP-dependent synthesis of glutathione (GSH) from gamma-glutamylcysteine and glycine; induced by oxidative stress and heat shock" |
| 4911 | YOL051W | GAL11 SGDID:S000005411, Chr XV from 234939-238184, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; affects transcription by acting as target of activators and repressors" |
| 4912 | YOL052C | SPE2 SGDID:S000005412, Chr XV from 233635-232445, reverse complement, Verified ORF, "S-adenosylmethionine decarboxylase, required for the biosynthesis of spermidine and spermine; cells lacking Spe2p require spermine or spermidine for growth in the presence of oxygen but not when grown anaerobically" |
| 4913 | YOL052C-A | DDR2 SGDID:S000005413, Chr XV from 231754-231569, reverse complement, Verified ORF, "Multistress response protein, expression is activated by a variety of xenobiotic agents and environmental or physiological stresses" |
| 4914 | YOL053W | YOL053W SGDID:S000005414, Chr XV from 230084-231271, Uncharacterized ORF, "Putative protein of unknown function; YOL053W is not an essential gene; null mutant displays decreased frequency of mitochondrial genome loss (petite formation)" |
| 4915 | YOL054W | PSH1 SGDID:S000005415, Chr XV from 228613-229833, Uncharacterized ORF, "Nuclear protein, putative RNA polymerase II elongation factor; isolated as Pob3p/Spt16p-binding protein" |
| 4916 | YOL055C | THI20 SGDID:S000005416, Chr XV from 226074-224419, reverse complement, Verified ORF, "Multifunctional protein with both hydroxymethylpyrimidine kinase and thiaminase activities; involved in thiamine biosynthesis and also in thiamine degradation; member of a gene family with THI21 and THI22; functionally redundant with Thi21p" |
| 4917 | YOL056W | GPM3 SGDID:S000005417, Chr XV from 223267-224178, Verified ORF, "Homolog of Gpm1p phosphoglycerate mutase, which converts 3-phosphoglycerate to 2-phosphoglycerate in glycolysis; may be non-functional derivative of a gene duplication event" |
| 4918 | YOL057W | YOL057W SGDID:S000005418, Chr XV from 220766-222901, Uncharacterized ORF, "Putative metalloprotease" |
| 4919 | YOL058W | ARG1 SGDID:S000005419, Chr XV from 219210-220472, Verified ORF, "Arginosuccinate synthetase, catalyzes the formation of L-argininosuccinate from citrulline and L-aspartate in the arginine biosynthesis pathway; potential Cdc28p substrate" |
| 4920 | YOL059W | GPD2 SGDID:S000005420, Chr XV from 217126-218448, Verified ORF, "NAD-dependent glycerol 3-phosphate dehydrogenase, homolog of Gpd1p, expression is controlled by an oxygen-independent signaling pathway required to regulate metabolism under anoxic conditions; located in cytosol and mitochondria" |
| 4921 | YOL060C | MAM3 SGDID:S000005421, Chr XV from 216137-214017, reverse complement, Verified ORF, "Protein required for normal mitochondrial morphology, has similarity to hemolysins" |
| 4922 | YOL061W | PRS5 SGDID:S000005422, Chr XV from 212244-213734, Verified ORF, "5-phospho-ribosyl-1(alpha)-pyrophosphate synthetase, synthesizes PRPP, which is required for nucleotide, histidine, and tryptophan biosynthesis; one of five related enzymes, which are active as heteromultimeric complexes" |
| 4923 | YOL062C | APM4 SGDID:S000005423, Chr XV from 211995-210520, reverse complement, Verified ORF, "Mu2-like subunit of the clathrin associated protein complex (AP-2); involved in vesicle transport" |
| 4924 | YOL063C | CRT10 SGDID:S000005424, Chr XV from 210265-207392, reverse complement, Verified ORF, "Protein involved in transcriptional regulation of RNR2 and RNR3; expression of the gene is induced by DNA damage and null mutations confer increased resistance to hydroxyurea; N-terminal region has a leucine repeat and a WD40 repeat" |
| 4925 | YOL064C | MET22 SGDID:S000005425, Chr XV from 207176-206103, reverse complement, Verified ORF, "Bisphosphate-3'-nucleotidase, involved in salt tolerance and methionine biogenesis; dephosphorylates 3'-phosphoadenosine-5'-phosphate and 3'-phosphoadenosine-5'-phosphosulfate, intermediates of the sulfate assimilation pathway" |
| 4926 | YOL065C | INP54 SGDID:S000005426, Chr XV from 205885-204731, reverse complement, Verified ORF, "Phosphatidylinositol 4,5-bisphosphate 5-phosphatase with a role in secretion, localizes to the endoplasmic reticulum via the C-terminal tail; lacks the Sac1 domain and proline-rich region found in the other 3 INP proteins" |
| 4927 | YOL066C | RIB2 SGDID:S000005427, Chr XV from 204471-202696, reverse complement, Verified ORF, "DRAP deaminase, catalyzes the third step of the riboflavin biosynthesis pathway; cytoplasmic tRNA pseudouridine synthase involved in pseudouridylation of cytoplasmic tRNAs at position 32" |
| 4928 | YOL067C | RTG1 SGDID:S000005428, Chr XV from 202518-201985, reverse complement, Verified ORF, "Transcription factor (bHLH) involved in interorganelle communication between mitochondria, peroxisomes, and nucleus" |
| 4929 | YOL068C | HST1 SGDID:S000005429, Chr XV from 201879-200368, reverse complement, Verified ORF, "NAD(+)-dependent histone deacetylase; essential subunit of the Sum1p/Rfm1p/Hst1p complex required for ORC-dependent silencing and mitotic repression; non-essential subunit of the Set3C deacetylase complex; involved in telomere maintenance" |
| 4930 | YOL069W | NUF2 SGDID:S000005430, Chr XV from 198942-200297, Verified ORF, "Component of the evolutionarily conserved kinetochore-associated Ndc80 complex (Ndc80p-Nuf2p-Spc24p-Spc25p); involved in chromosome segregation, spindle checkpoint activity and kinetochore clustering" |
| 4931 | YOL070C | NBA1 SGDID:S000005431, Chr XV from 198725-197220, reverse complement, Verified ORF, "Protein of unknown function, localizes to the bud neck and cytoplasm; interacts with Nap1p; may interact with ribosomes, based on co-purification experiments; potential Cdc28p substrate" |
| 4932 | YOL071W | EMI5 SGDID:S000005432, Chr XV from 196507-196995, Verified ORF, "Non-essential protein of unknown function required for transcriptional induction of the early meiotic-specific transcription factor IME1, also required for sporulation" |
| 4933 | YOL072W | THP1 SGDID:S000005433, Chr XV from 194970-196337, Verified ORF, "Nuclear pore-associated protein, forms a complex with Sac3p that is involved in transcription and in mRNA export from the nucleus; contains a PAM domain implicated in protein-protein binding" |
| 4934 | YOL073C | YOL073C SGDID:S000005434, Chr XV from 194800-193832, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 4935 | YOL075C | YOL075C SGDID:S000005435, Chr XV from 193542-189658, reverse complement, Uncharacterized ORF, "Putative ABC transporter" |
| 4936 | YOL076W | MDM20 SGDID:S000005436, Chr XV from 187024-189414, Verified ORF, "Non-catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes N-acetylation of proteins with specific N-terminal sequences; involved in mitochondrial inheritance and actin assembly" |
| 4937 | YOL077C | BRX1 SGDID:S000005437, Chr XV from 186723-185848, reverse complement, Verified ORF, "Nucleolar protein, constituent of 66S pre-ribosomal particles; depletion leads to defects in rRNA processing and a block in the assembly of large ribosomal subunits; possesses a sigma(70)-like RNA-binding motif" |
| 4938 | YOL077W-A | ATP19 SGDID:S000007339, Chr XV from 185438-185644, Verified ORF, "Subunit k of the mitochondrial F1F0 ATP synthase, which is a large enzyme complex required for ATP synthesis; associated only with the dimeric form of ATP synthase" |
| 4939 | YOL078W | AVO1 SGDID:S000005438, Chr XV from 181682-185212, Verified ORF, "Component of a membrane-bound complex containing the Tor2p kinase and other proteins, which may have a role in regulation of cell growth" |
| 4940 | YOL080C | REX4 SGDID:S000005440, Chr XV from 181427-180558, reverse complement, Verified ORF, "Putative RNA exonuclease possibly involved in pre-rRNA processing and ribosome assembly" |
| 4941 | YOL081W | IRA2 SGDID:S000005441, Chr XV from 171070-180309, Verified ORF, "GTPase-activating protein that negatively regulates RAS by converting it from the GTP- to the GDP-bound inactive form, required for reducing cAMP levels under nutrient limiting conditions, has similarity to Ira1p and human neurofibromin" |
| 4942 | YOL082W | ATG19 SGDID:S000005442, Chr XV from 168727-169974, Verified ORF, "Receptor protein for the cytoplasm-to-vacuole targeting (Cvt) pathway; recognizes cargo proteins aminopeptidase I (Lap4p) and alpha-mannosidase (Ams1p) and delivers them to the preautophagosomal structure for packaging into Cvt vesicles" |
| 4943 | YOL083W | YOL083W SGDID:S000005443, Chr XV from 165714-166952, Uncharacterized ORF, "Hypothetical protein" |
| 4944 | YOL084W | PHM7 SGDID:S000005444, Chr XV from 162356-165331, Verified ORF, "Protein of unknown function, expression is regulated by phosphate levels; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery and vacuole" |
| 4945 | YOL086C | ADH1 SGDID:S000005446, Chr XV from 160594-159548, reverse complement, Verified ORF, "Alcohol dehydrogenase, fermentative isozyme active as homo- or heterotetramers; required for the reduction of acetaldehyde to ethanol, the last step in the glycolytic pathway" |
| 4946 | YOL086W-A | YOL086W-A SGDID:S000007626, Chr XV from 159173-159445, Uncharacterized ORF, "Putative protein of unknown function; identified by homology" |
| 4947 | YOL087C | YOL087C SGDID:S000005447, Chr XV from 158637-155287, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; deletion mutant is sensitive to various chemicals including phenanthroline, sanguinarine, and nordihydroguaiaretic acid" |
| 4948 | YOL088C | MPD2 SGDID:S000005448, Chr XV from 154745-153912, reverse complement, Verified ORF, "Member of the protein disulfide isomerase (PDI) family, exhibits chaperone activity; overexpression suppresses the lethality of a pdi1 deletion but does not complement all Pdi1p functions; undergoes oxidation by Ero1p" |
| 4949 | YOL089C | HAL9 SGDID:S000005449, Chr XV from 153490-150398, reverse complement, Verified ORF, "Putative transcription factor containing a zinc finger; overexpression increases salt tolerance through increased expression of the ENA1 (Na+/Li+ extrusion pump) gene while gene disruption decreases both salt tolerance and ENA1 expression" |
| 4950 | YOL090W | MSH2 SGDID:S000005450, Chr XV from 147382-150276, Verified ORF, "Protein that forms heterodimers with Msh3p and Msh6p that bind to DNA mismatches to initiate the mismatch repair process; contains a Walker ATP-binding motif required for repair activity; Msh2p-Msh6p binds to and hydrolyzes ATP" |
| 4951 | YOL091W | SPO21 SGDID:S000005451, Chr XV from 145334-147163, Verified ORF, "Component of the meiotic outer plaque of the spindle pole body, involved in modifying the meiotic outer plaque that is required prior to prospore membrane formation" |
| 4952 | YOL092W | YOL092W SGDID:S000005452, Chr XV from 144204-145130, Uncharacterized ORF, "Putative protein of unknown function; predicted to contain six transmembrane domains and is 58% similar to the uncharacterized ORF YBR147W; deletion mutant has no detectable phenotype" |
| 4953 | YOL093W | TRM10 SGDID:S000005453, Chr XV from 142815-143696, Verified ORF, "tRNA methyltransferase, methylates the N-1 position of guanosine in tRNAs" |
| 4954 | YOL094C | RFC4 SGDID:S000005454, Chr XV from 142555-141584, reverse complement, Verified ORF, "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon" |
| 4955 | YOL095C | HMI1 SGDID:S000005455, Chr XV from 141347-139227, reverse complement, Verified ORF, "Mitochondrial inner membrane localized ATP-dependent DNA helicase, required for the maintenance of the mitochondrial genome; not required for mitochondrial transcription; has homology to E. coli helicase uvrD" |
| 4956 | YOL096C | COQ3 SGDID:S000005456, Chr XV from 139045-138107, reverse complement, Verified ORF, "O-methyltransferase, catalyzes two different O-methylation steps in ubiquinone (Coenzyme Q) biosynthesis; component of a mitochondrial ubiquinone-synthesizing complex" |
| 4957 | YOL097C | WRS1 SGDID:S000005457, Chr XV from 137825-136527, reverse complement, Verified ORF, "Cytoplasmic tryptophanyl-tRNA synthetase, aminoacylates tryptophanyl-tRNA" |
| 4958 | YOL097W-A | YOL097W-A SGDID:S000028854, Chr XV from 136220-136405, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 4959 | YOL098C | YOL098C SGDID:S000005458, Chr XV from 135838-132725, reverse complement, Uncharacterized ORF, "Putative metalloprotease" |
| 4960 | YOL100W | PKH2 SGDID:S000005460, Chr XV from 129237-132482, Verified ORF, "Serine/threonine protein kinase involved in sphingolipid-mediated signaling pathway that controls endocytosis; activates Ypk1p and Ykr2p, components of signaling cascade required for maintenance of cell wall integrity; redundant with Pkh1p" |
| 4961 | YOL101C | IZH4 SGDID:S000005461, Chr XV from 127920-126982, reverse complement, Verified ORF, "Membrane protein involved in zinc metabolism, member of the four-protein IZH family, expression induced by fatty acids and altered zinc levels; deletion reduces sensitivity to excess zinc; possible role in sterol metabolism" |
| 4962 | YOL102C | TPT1 SGDID:S000005462, Chr XV from 126689-125997, reverse complement, Verified ORF, "tRNA 2'-phosphotransferase, catalyzes the final step in yeast tRNA splicing: the transfer of the 2'-PO(4) from the splice junction to NAD(+) to form ADP-ribose 1''-2''cyclic phosphate and nicotinamide" |
| 4963 | YOL103W | ITR2 SGDID:S000005463, Chr XV from 124001-125830, Verified ORF, "Myo-inositol transporter with strong similarity to the major myo-inositol transporter Itr1p, member of the sugar transporter superfamily; expressed constitutively" |
| 4964 | YOL103W-A | YOL103W-A SGDID:S000007349, Chr XV from 118000-119322, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 4965 | YOL103W-B | YOL103W-B SGDID:S000007350, Chr XV from 118000-119304,119306-123268, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 4966 | YOL104C | NDJ1 SGDID:S000005464, Chr XV from 117454-116396, reverse complement, Verified ORF, "Meiosis-specific telomere protein, required for bouquet formation, effective homolog pairing, ordered cross-over distribution (interference), sister chromatid cohesion at meiotic telomeres, and segregation of small chromosomes" |
| 4967 | YOL105C | WSC3 SGDID:S000005465, Chr XV from 115808-114138, reverse complement, Verified ORF, "Partially redundant sensor-transducer of the stress-activated PKC1-MPK1 signaling pathway involved in maintenance of cell wall integrity; involved in the response to heat shock and other stressors; regulates 1,3-beta-glucan synthesis" |
| 4968 | YOL107W | YOL107W SGDID:S000005467, Chr XV from 112102-113130, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and colocalizes in a punctate pattern with the early golgi/COPI vesicles; YOL107W is not an essential protein" |
| 4969 | YOL108C | INO4 SGDID:S000005468, Chr XV from 111886-111431, reverse complement, Verified ORF, "Transcription factor required for derepression of inositol-choline-regulated genes involved in phospholipid synthesis; forms a complex, with Ino2p, that binds the inositol-choline-responsive element through a basic helix-loop-helix domain" |
| 4970 | YOL109W | ZEO1 SGDID:S000005469, Chr XV from 110297-110638, Verified ORF, "Peripheral membrane protein of the plasma membrane that interacts with Mid2p; regulates the cell integrity pathway mediated by Pkc1p and Slt2p; the authentic protein is detected in a phosphorylated state in highly purified mitochondria" |
| 4971 | YOL110W | SHR5 SGDID:S000005470, Chr XV from 109176-109889, Verified ORF, "Subunit of a palmitoyltransferase, composed of Shr5p and Erf2p, that adds a palmitoyl lipid moiety to heterolipidated substrates such as Ras1p and Ras2p through a thioester linkage; palmitoylation is required for Ras2p membrane localization" |
| 4972 | YOL111C | MDY2 SGDID:S000005471, Chr XV from 108896-108258, reverse complement, Verified ORF, "Protein required for efficient mating; involved in shmoo formation and nuclear migration in the pre-zygote; associates with ribosomes and interacts with YOR164C; contains a ubiquitin-like (UBL) domain" |
| 4973 | YOL112W | MSB4 SGDID:S000005472, Chr XV from 106710-108188, Verified ORF, "GTPase-activating protein of the Ras superfamily that acts primarily on Sec4p, localizes to the bud site and bud tip, has similarity to Msb3p; msb3 msb4 double mutation causes defects in secretion and actin organization" |
| 4974 | YOL113W | SKM1 SGDID:S000005473, Chr XV from 104326-106293, Verified ORF, "Member of the PAK family of serine/threonine protein kinases with similarity to Ste20p and Cla4p; proposed to be a downstream effector of Cdc42p during polarized growth" |
| 4975 | YOL114C | YOL114C SGDID:S000005474, Chr XV from 103925-103317, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with similarity to human ICT1 and prokaryotic factors that may function in translation termination; YOL114C is not an essential gene" |
| 4976 | YOL115W | PAP2 SGDID:S000005475, Chr XV from 101475-103229, Verified ORF, "Catalytic subunit of TRAMP (Trf4/Pap2p-Mtr4p-Air1p/2p), a nuclear poly (A) polymerase complex involved in RNA quality control; catalyzes polyadenylation of unmodified tRNAs, and snoRNA and rRNA precursors; disputed role as a DNA polymerase" |
| 4977 | YOL116W | MSN1 SGDID:S000005476, Chr XV from 99809-100957, Verified ORF, "Transcriptional activator involved in regulation of invertase and glucoamylase expression, invasive growth and pseudohyphal differentiation, iron uptake, chromium accumulation, and response to osmotic stress; localizes to the nucleus" |
| 4978 | YOL117W | RRI2 SGDID:S000005477, Chr XV from 97551-99488, Verified ORF, "Subunit of the COP9 signalosome (CSN) complex that cleaves the ubiquitin-like protein Nedd8 from SCF ubiquitin ligases; plays a role in the mating pheromone response" |
| 4979 | YOL119C | MCH4 SGDID:S000005479, Chr XV from 96361-94856, reverse complement, Verified ORF, "Protein with similarity to mammalian monocarboxylate permeases, which are involved in transport of monocarboxylic acids across the plasma membrane; mutant is not deficient in monocarboxylate transport" |
| 4980 | YOL120C | RPL18A SGDID:S000005480, Chr XV from 94402-94291,93843-93395, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, identical to Rpl18Bp and has similarity to rat L18 ribosomal protein; intron of RPL18A pre-mRNA forms stem-loop structures that are a target for Rnt1p cleavage leading to degradation" |
| 4981 | YOL121C | RPS19A SGDID:S000005481, Chr XV from 92850-92831,92440-92026, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit, required for assembly and maturation of pre-40 S particles; mutations in human RPS19 are associated with Diamond Blackfan anemia; nearly identical to Rps19Bp" |
| 4982 | YOL122C | SMF1 SGDID:S000005482, Chr XV from 91419-89692, reverse complement, Verified ORF, "Divalent metal ion transporter with a broad specificity for di-valent and tri-valent metals; post-translationally regulated by levels of metal ions; member of the Nramp family of metal transport proteins" |
| 4983 | YOL123W | HRP1 SGDID:S000005483, Chr XV from 87844-89448, Verified ORF, "Subunit of cleavage factor I, a five-subunit complex required for the cleavage and polyadenylation of pre-mRNA 3' ends; RRM-containing heteronuclear RNA binding protein and hnRNPA/B family member that binds to poly (A) signal sequences" |
| 4984 | YOL124C | TRM11 SGDID:S000005484, Chr XV from 86757-85456, reverse complement, Verified ORF, "Catalytic subunit of an adoMet-dependent tRNA methyltransferase complex (Trm11p-Trm112p), required for the methylation of the guanosine nucleotide at position 10 (m2G10) in tRNAs; contains a THUMP domain and a methyltransferase domain" |
| 4985 | YOL125W | TRM13 SGDID:S000005485, Chr XV from 83834-85264, Verified ORF, "2'-O-methyltransferase responsible for modification of tRNA at position 4; exhibits no obvious similarity to other known methyltransferases" |
| 4986 | YOL126C | MDH2 SGDID:S000005486, Chr XV from 82920-81787, reverse complement, Verified ORF, "Cytoplasmic malate dehydrogenase, one of three isozymes that catalyze interconversion of malate and oxaloacetate; involved in the glyoxylate cycle and gluconeogenesis during growth on two-carbon compounds; interacts with Pck1p and Fbp1" |
| 4987 | YOL127W | RPL25 SGDID:S000005487, Chr XV from 80348-80360,80775-81190, Verified ORF, "Primary rRNA-binding ribosomal protein component of the large (60S) ribosomal subunit, has similarity to E. coli L23 and rat L23a ribosomal proteins; binds to 26S rRNA via a conserved C-terminal motif" |
| 4988 | YOL128C | YGK3 SGDID:S000005488, Chr XV from 79479-78352, reverse complement, Verified ORF, "Protein kinase related to mammalian glycogen synthase kinases of the GSK-3 family; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation" |
| 4989 | YOL129W | VPS68 SGDID:S000005489, Chr XV from 77560-78114, Verified ORF, "Vacuolar membrane protein of unknown function involved in vacuolar protein sorting; also detected in the mitochondria" |
| 4990 | YOL130W | ALR1 SGDID:S000005490, Chr XV from 74400-76979, Verified ORF, "Plasma membrane Mg(2+) transporter, expression and turnover are regulated by Mg(2+) concentration; overexpression confers increased tolerance to Al(3+) and Ga(3+) ions" |
| 4991 | YOL131W | YOL131W SGDID:S000005491, Chr XV from 73031-73357, Uncharacterized ORF, "Putative protein of unknown function" |
| 4992 | YOL132W | GAS4 SGDID:S000005492, Chr XV from 71300-72715, Verified ORF, "1,3-beta-glucanosyltransferase, involved with Gas2p in spore wall assembly; has similarity to Gas1p; localizes to the cell wall" |
| 4993 | YOL133W | HRT1 SGDID:S000005493, Chr XV from 70325-70690, Verified ORF, "RING finger containing subunit of Skp1-Cullin-F-box ubiquitin protein ligases (SCF); required for Gic2p, Far1p, Sic1p and Cln2p degradation; may tether Cdc34p (a ubiquitin conjugating enzyme or E2) and Cdc53p (a cullin) subunits of SCF" |
| 4994 | YOL135C | MED7 SGDID:S000005495, Chr XV from 70044-69376, reverse complement, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation" |
| 4995 | YOL136C | PFK27 SGDID:S000005496, Chr XV from 68754-67561, reverse complement, Verified ORF, "6-phosphofructo-2-kinase, catalyzes synthesis of fructose-2,6-bisphosphate; inhibited by phosphoenolpyruvate and sn-glycerol 3-phosphate, expression induced by glucose and sucrose, transcriptional regulation involves protein kinase A" |
| 4996 | YOL137W | BSC6 SGDID:S000005497, Chr XV from 65621-67114, Verified ORF, "Protein of unknown function containing 8 putative transmembrane seqments; ORF exhibits genomic organization compatible with a translational readthrough-dependent mode of expression" |
| 4997 | YOL138C | YOL138C SGDID:S000005498, Chr XV from 65350-61325, reverse complement, Verified ORF, "Putative protein of unknown function; may interact with ribosomes, based on co-purification experiments; null mutation suppresses cdc13-1 temperature sensitivity" |
| 4998 | YOL139C | CDC33 SGDID:S000005499, Chr XV from 61024-60383, reverse complement, Verified ORF, "Cytoplasmic mRNA cap binding protein; the eIF4E-cap complex is responsible for mediating cap-dependent mRNA translation via interactions with the translation initiation factor eIF4G (Tif4631p or Tif4632p)" |
| 4999 | YOL140W | ARG8 SGDID:S000005500, Chr XV from 58759-60030, Verified ORF, "Acetylornithine aminotransferase, catalyzes the fourth step in the biosynthesis of the arginine precursor ornithine" |
| 5000 | YOL141W | PPM2 SGDID:S000005501, Chr XV from 56451-58538, Verified ORF, "tRNA methyltransferase required for the synthesis of wybutosine, a modified guanosine found at the 3'-position adjacent to the anticodon of phe-tRNA; similar to Ppm1p carboxymethyltransferase" |
| 5001 | YOL142W | RRP40 SGDID:S000005502, Chr XV from 55557-56279, Verified ORF, "Protein involved in rRNA processing; component of the exosome 3->5 exonuclease complex" |
| 5002 | YOL143C | RIB4 SGDID:S000005503, Chr XV from 55103-54594, reverse complement, Verified ORF, "Lumazine synthase (6,7-dimethyl-8-ribityllumazine synthase, also known as DMRL synthase); catalyzes synthesis of immediate precursor to riboflavin" |
| 5003 | YOL144W | NOP8 SGDID:S000005504, Chr XV from 53097-54551, Verified ORF, "Nucleolar protein required for 60S ribosomal subunit biogenesis" |
| 5004 | YOL145C | CTR9 SGDID:S000005505, Chr XV from 52787-49554, reverse complement, Verified ORF, "Component of the Paf1p complex, which is a large complex that binds to and modulates the activity of RNA polymerase II and is required for expression of a subset of genes, including cyclin genes; contains TPR repeats" |
| 5005 | YOL146W | PSF3 SGDID:S000005506, Chr XV from 48863-49447, Verified ORF, "Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p), which is localized to DNA replication origins and implicated in assembly of the DNA replication machinery" |
| 5006 | YOL147C | PEX11 SGDID:S000005507, Chr XV from 48642-47932, reverse complement, Verified ORF, "Peroxisomal membrane protein required for peroxisome proliferation and medium-chain fatty acid oxidation, most abundant protein in the peroxisomal membrane, regulated by Adr1p and Pip2p-Oaf1p, promoter contains ORE and UAS1-like elements" |
| 5007 | YOL148C | SPT20 SGDID:S000005508, Chr XV from 47573-45759, reverse complement, Verified ORF, "Subunit of the SAGA transcriptional regulatory complex, involved in maintaining the integrity of the complex" |
| 5008 | YOL149W | DCP1 SGDID:S000005509, Chr XV from 44937-45632, Verified ORF, "Subunit of the Dcp1p-Dcp2p decapping enzyme complex, which removes the 5' cap structure from mRNAs prior to their degradation; enhances the activity of catalytic subunit Dcp2p; regulated by DEAD box protein Dhh1p" |
| 5009 | YOL151W | GRE2 SGDID:S000005511, Chr XV from 43693-44721, Verified ORF, "3-methylbutanal reductase and NADPH-dependent methylglyoxal reductase (D-lactaldehyde dehydrogenase); stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway" |
| 5010 | YOL152W | FRE7 SGDID:S000005512, Chr XV from 40747-42609, Verified ORF, "Putative ferric reductase with similarity to Fre2p; expression induced by low copper levels" |
| 5011 | YOL154W | ZPS1 SGDID:S000005514, Chr XV from 34657-35406, Verified ORF, "Putative GPI-anchored protein; transcription is induced under low-zinc conditions, as mediated by the Zap1p transcription factor, and at alkaline pH" |
| 5012 | YOL155C | HPF1 SGDID:S000005515, Chr XV from 31605-28702, reverse complement, Verified ORF, "Haze-protective mannoprotein that reduces the particle size of aggregated proteins in white wines" |
| 5013 | YOL155W-A | YOL155W-A SGDID:S000028855, Chr XV from 27083-27217, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 5014 | YOL156W | HXT11 SGDID:S000005516, Chr XV from 25272-26975, Verified ORF, "Putative hexose transporter that is nearly identical to Hxt9p, has similarity to major facilitator superfamily (MFS) transporters and is involved in pleiotropic drug resistance" |
| 5015 | YOL157C | YOL157C SGDID:S000005517, Chr XV from 24293-22524, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 5016 | YOL158C | ENB1 SGDID:S000005518, Chr XV from 21310-19490, reverse complement, Verified ORF, "Endosomal ferric enterobactin transporter, expressed under conditions of iron deprivation; member of the major facilitator superfamily; expression is regulated by Rcs1p and affected by chloroquine treatment" |
| 5017 | YOL159C | YOL159C SGDID:S000005519, Chr XV from 17795-17280, reverse complement, Verified ORF, "Soluble protein of unknown function; deletion mutants are viable and have elevated levels of Ty1 retrotransposition and Ty1 cDNA" |
| 5018 | YOL159C-A | YOL159C-A SGDID:S000007627, Chr XV from 15504-15232, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by sequence comparison with hemiascomycetous yeast species" |
| 5019 | YOL161C | YOL161C SGDID:S000005521, Chr XV from 11910-11548, reverse complement, Uncharacterized ORF, "Hypothetical protein" |
| 5020 | YOL162W | YOL162W SGDID:S000005522, Chr XV from 10118-10765, Uncharacterized ORF, "Putative protein of unknown function; member of the Dal5p subfamily of the major facilitator family" |
| 5021 | YOL163W | YOL163W SGDID:S000005523, Chr XV from 9596-10105, Uncharacterized ORF, "Putative protein of unknown function; member of the Dal5p subfamily of the major facilitator family" |
| 5022 | YOL164W | BDS1 SGDID:S000005524, Chr XV from 6175-8115, Verified ORF, "Bacterially-derived sulfatase required for use of alkyl- and aryl-sulfates as sulfur sources" |
| 5023 | YOL164W-A | YOL164W-A SGDID:S000028580, Chr XV from 4130-4312, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 5024 | YOL165C | AAD15 SGDID:S000005525, Chr XV from 2078-1647, reverse complement, Verified ORF, "Putative aryl-alcohol dehydrogenase with similarity to P. chrysosporium aryl-alcohol dehydrogenase; mutational analysis has not yet revealed a physiological role" |
| 5025 | YOL166W-A | YOL166W-A SGDID:S000028709, Chr XV from 585-740, Uncharacterized ORF, "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 5026 | YOR001W | RRP6 SGDID:S000005527, Chr XV from 326833-329034, Verified ORF, "Exonuclease component of the nuclear exosome; contributes to the quality-control system that retains and degrades aberrant mRNAs in the nucleus" |
| 5027 | YOR002W | ALG6 SGDID:S000005528, Chr XV from 329418-331052, Verified ORF, "Alpha 1,3 glucosyltransferase, involved in transfer of oligosaccharides from dolichyl pyrophosphate to asparagine residues of proteins during N-linked protein glycosylation; mutations in human ortholog are associated with disease" |
| 5028 | YOR003W | YSP3 SGDID:S000005529, Chr XV from 331456-332892, Verified ORF, "Putative precursor to the subtilisin-like protease III" |
| 5029 | YOR004W | UTP23 SGDID:S000005530, Chr XV from 333593-334357, Verified ORF, "Essential nucleolar protein that is a component of the SSU (small subunit) processome involved in 40S ribosomal subunit biogenesis; has homology to PINc domain protein Fcf1p, although the PINc domain of Utp23p is not required for function" |
| 5030 | YOR005C | DNL4 SGDID:S000005531, Chr XV from 337344-334510, reverse complement, Verified ORF, "DNA ligase required for nonhomologous end-joining (NHEJ), forms stable heterodimer with required cofactor Lif1p, interacts with Nej1p; involved in meiosis, not essential for vegetative growth" |
| 5031 | YOR006C | YOR006C SGDID:S000005532, Chr XV from 338622-337681, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus; Null mutant accumulates 20S pre-rRNA" |
| 5032 | YOR007C | SGT2 SGDID:S000005533, Chr XV from 339979-338939, reverse complement, Verified ORF, "Glutamine-rich cytoplasmic protein of unknown function; contains tetratricopeptide (TPR) repeats, which often mediate protein-protein interactions; has similarity to human SGT, which is a cochaperone that negatively regulates Hsp70" |
| 5033 | YOR008C | SLG1 SGDID:S000005534, Chr XV from 342415-341279, reverse complement, Verified ORF, "Sensor-transducer of the stress-activated PKC1-MPK1 kinase pathway involved in maintenance of cell wall integrity; involved in organization of the actin cytoskeleton; secretory pathway Wsc1p is required for the arrest of secretion response" |
| 5034 | YOR008C-A | YOR008C-A SGDID:S000006431, Chr XV from 343082-342858, reverse complement, Uncharacterized ORF, "Putative protein of unknown function, includes a potential transmembrane domain; deletion results in slightly lengthened telomeres" |
| 5035 | YOR009W | TIR4 SGDID:S000005535, Chr XV from 344335-345798, Verified ORF, "Cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; expressed under anaerobic conditions and required for anaerobic growth; transcription is also induced by cold shock" |
| 5036 | YOR010C | TIR2 SGDID:S000005536, Chr XV from 346950-346195, reverse complement, Verified ORF, "Putative cell wall mannoprotein of the Srp1p/Tip1p family of serine-alanine-rich proteins; transcription is induced by cold shock and anaerobiosis" |
| 5037 | YOR011W | AUS1 SGDID:S000005537, Chr XV from 349679-353863, Verified ORF, "Transporter of the ATP-binding cassette family, involved in uptake of sterols and anaerobic growth" |
| 5038 | YOR011W-A | YOR011W-A SGDID:S000028581, Chr XV from 355652-355858, Uncharacterized ORF, "Putative protein of unknown function" |
| 5039 | YOR012W | YOR012W SGDID:S000005538, Chr XV from 356543-356956, Uncharacterized ORF, "Putative protein of unknown function" |
| 5040 | YOR014W | RTS1 SGDID:S000005540, Chr XV from 357674-359947, Verified ORF, "B-type regulatory subunit of protein phosphatase 2A (PP2A); homolog of the mammalian B' subunit of PP2A" |
| 5041 | YOR016C | ERP4 SGDID:S000005542, Chr XV from 361084-360461, reverse complement, Verified ORF, "Protein with similarity to Emp24p and Erv25p, member of the p24 family involved in ER to Golgi transport" |
| 5042 | YOR017W | PET127 SGDID:S000005543, Chr XV from 361412-363814, Verified ORF, "Protein with a role in 5'-end processing of mitochondrial RNAs, located in the mitochondrial membrane" |
| 5043 | YOR018W | ROD1 SGDID:S000005544, Chr XV from 364369-366882, Verified ORF, "Membrane protein; overexpression confers resistance to the GST substrate o-dinitrobenzene as well as to zinc and calcium; contains 2 PY motifs, which are required for Rod1p interaction with Rsp5p, a hect-type ubiquitin ligase" |
| 5044 | YOR019W | YOR019W SGDID:S000005545, Chr XV from 368127-370319, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments" |
| 5045 | YOR020C | HSP10 SGDID:S000005546, Chr XV from 370844-370524, reverse complement, Verified ORF, "Mitochondrial matrix co-chaperonin that inhibits the ATPase activity of Hsp60p, a mitochondrial chaperonin; involved in protein folding and sorting in the mitochondria; 10 kD heat shock protein with similarity to E. coli groES" |
| 5046 | YOR020W-A | YOR020W-A SGDID:S000028526, Chr XV from 371685-371957, Uncharacterized ORF, "Putative protein of unknown function, conserved in A. gossypii; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 5047 | YOR021C | YOR021C SGDID:S000005547, Chr XV from 373439-372798, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YOR021C is not an essential gene" |
| 5048 | YOR022C | YOR022C SGDID:S000005548, Chr XV from 375857-373710, reverse complement, Uncharacterized ORF, "Protein with similarity to bovine phospholipase A1; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 5049 | YOR023C | AHC1 SGDID:S000005549, Chr XV from 377712-376012, reverse complement, Verified ORF, "Subunit of the Ada histone acetyltransferase complex, required for structural integrity of the complex" |
| 5050 | YOR025W | HST3 SGDID:S000005551, Chr XV from 378219-379562, Verified ORF, "Member of the Sir2 family of NAD(+)-dependent protein deacetylases; involved along with Hst4p in telomeric silencing, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism" |
| 5051 | YOR026W | BUB3 SGDID:S000005552, Chr XV from 379781-380806, Verified ORF, "Kinetochore checkpoint WD40 repeat protein that localizes to kinetochores during prophase and metaphase, delays anaphase in the presence of unattached kinetochores; forms complexes with Mad1p-Bub1p and with Cdc20p, binds Mad2p and Mad3p" |
| 5052 | YOR027W | STI1 SGDID:S000005553, Chr XV from 381053-382822, Verified ORF, "Hsp90 cochaperone, interacts with the Ssa group of the cytosolic Hsp70 chaperones; activates the ATPase activity of Ssa1p; homolog of mammalian Hop protein" |
| 5053 | YOR028C | CIN5 SGDID:S000005554, Chr XV from 384420-383533, reverse complement, Verified ORF, "Basic leucine zipper transcriptional factor of the yAP-1 family that mediates pleiotropic drug resistance and salt tolerance; localizes constitutively to the nucleus" |
| 5054 | YOR030W | DFG16 SGDID:S000005556, Chr XV from 386825-388684, Verified ORF, "Probable multiple transmembrane protein, involved in diploid invasive and pseudohyphal growth upon nitrogen starvation; required for accumulation of processed Rim101p" |
| 5055 | YOR031W | CRS5 SGDID:S000005557, Chr XV from 389213-389422, Verified ORF, "Copper-binding metallothionein, required for wild-type copper resistance" |
| 5056 | YOR032C | HMS1 SGDID:S000005558, Chr XV from 391075-389771, reverse complement, Verified ORF, "Basic helix-loop-helix (bHLH) protein with similarity to myc-family transcription factors; overexpression confers hyperfilamentous growth and suppresses the pseudohyphal filamentation defect of a diploid mep1 mep2 homozygous null mutant" |
| 5057 | YOR032W-A | YOR032W-A SGDID:S000028710, Chr XV from 392176-392376, Uncharacterized ORF, "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 5058 | YOR033C | EXO1 SGDID:S000005559, Chr XV from 394524-392416, reverse complement, Verified ORF, "5'-3' exonuclease and flap-endonuclease involved in recombination, double-strand break repair and DNA mismatch repair; member of the Rad2p nuclease family, with conserved N and I nuclease domains" |
| 5059 | YOR034C | AKR2 SGDID:S000005560, Chr XV from 397086-394837, reverse complement, Verified ORF, "Ankyrin repeat-containing protein similar to Akr1p; member of a family of putative palmitoyltransferases containing an Asp-His-His-Cys-cysteine rich (DHHC-CRD) domain; possibly involved in constitutive endocytosis of Ste3p" |
| 5060 | YOR034C-A | YOR034C-A SGDID:S000028856, Chr XV from 397668-397426, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 5061 | YOR035C | SHE4 SGDID:S000005561, Chr XV from 400104-397735, reverse complement, Verified ORF, "Protein containing a UCS (UNC-45/CRO1/SHE4) domain, binds to myosin motor domains to regulate myosin function; involved in endocytosis, polarization of the actin cytoskeleton, and asymmetric mRNA localization" |
| 5062 | YOR036W | PEP12 SGDID:S000005562, Chr XV from 400348-401214, Verified ORF, "Target membrane receptor (t-SNARE) for vesicular intermediates traveling between the Golgi apparatus and the vacuole; controls entry of biosynthetic, endocytic, and retrograde traffic into the prevacuolar compartment; syntaxin" |
| 5063 | YOR037W | CYC2 SGDID:S000005563, Chr XV from 401555-402655, Verified ORF, "Mitochondrial peripheral inner membrane protein, contains a FAD cofactor in a domain exposed in the intermembrane space; exhibits redox activity in vitro; likely participates in ligation of heme to acytochromes c and c1 (Cyc1p and Cyt1p)" |
| 5064 | YOR038C | HIR2 SGDID:S000005564, Chr XV from 405388-402761, reverse complement, Verified ORF, "Subunit of the HIR complex, a nucleosome assembly complex involved in regulation of histone gene transcription; recruits Swi-Snf complexes to histone gene promoters; promotes heterochromatic gene silencing with Asf1p" |
| 5065 | YOR039W | CKB2 SGDID:S000005565, Chr XV from 405768-406544, Verified ORF, "Beta' regulatory subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKA2 and CKB1, the many substrates include transcription factors and all RNA polymerases" |
| 5066 | YOR040W | GLO4 SGDID:S000005566, Chr XV from 407064-407921, Verified ORF, "Mitochondrial glyoxalase II, catalyzes the hydrolysis of S-D-lactoylglutathione into glutathione and D-lactate" |
| 5067 | YOR042W | CUE5 SGDID:S000005568, Chr XV from 408425-409660, Verified ORF, "Protein containing a CUE domain that binds ubiquitin, which may facilitate intramolecular monoubiquitination; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 5068 | YOR043W | WHI2 SGDID:S000005569, Chr XV from 410870-412330, Verified ORF, "Protein required, with binding partner Psr1p, for full activation of the general stress response, possibly through Msn2p dephosphorylation; regulates growth during the diauxic shift; negative regulator of G1 cyclin expression" |
| 5069 | YOR044W | IRC23 SGDID:S000005570, Chr XV from 413007-413480, Verified ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion localizes to the ER; null mutant displays increased levels of spontaneous Rad52p foci" |
| 5070 | YOR045W | TOM6 SGDID:S000005571, Chr XV from 413852-414037, Verified ORF, "Component of the TOM (translocase of outer membrane) complex responsible for recognition and initial import steps for all mitochondrially directed proteins; promotes assembly and stability of the TOM complex" |
| 5071 | YOR046C | DBP5 SGDID:S000005572, Chr XV from 415908-414460, reverse complement, Verified ORF, "Cytoplasmic ATP-dependent RNA helicase of the DEAD-box family involved in mRNA export from the nucleus; involved in translation termination" |
| 5072 | YOR047C | STD1 SGDID:S000005573, Chr XV from 417682-416348, reverse complement, Verified ORF, "Protein involved in control of glucose-regulated gene expression; interacts with protein kinase Snf1p, glucose sensors Snf3p and Rgt2p, and TATA-binding protein Spt15p; acts as a regulator of the transcription factor Rgt1p" |
| 5073 | YOR048C | RAT1 SGDID:S000005574, Chr XV from 421651-418631, reverse complement, Verified ORF, "Nuclear 5' to 3' single-stranded RNA exonuclease, involved in RNA metabolism, including rRNA and snRNA processing as well as mRNA transcription termination" |
| 5074 | YOR049C | RSB1 SGDID:S000005575, Chr XV from 423733-422669, reverse complement, Verified ORF, "Suppressor of sphingoid long chain base (LCB) sensitivity of an LCB-lyase mutation; putative integral membrane transporter or flippase that may transport LCBs from the cytoplasmic side toward the extracytoplasmic side of the membrane" |
| 5075 | YOR051C | YOR051C SGDID:S000005577, Chr XV from 426086-424848, reverse complement, Uncharacterized ORF, "Nuclear protein that inhibits replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts" |
| 5076 | YOR052C | YOR052C SGDID:S000005578, Chr XV from 427226-426774, reverse complement, Verified ORF, "Nuclear protein of unknown function; expression induced by nitrogen limitation in a GLN3, GAT1-independent manner and by weak acid" |
| 5077 | YOR054C | VHS3 SGDID:S000005580, Chr XV from 429859-427835, reverse complement, Verified ORF, "Functionally redundant (see also SIS2) inhibitory subunit of Ppz1p, a PP1c-related ser/thr protein phosphatase Z isoform; synthetically lethal with sis2; putative phosphopantothenoylcysteine decarboxylase involved in coenzyme A biosynthesis" |
| 5078 | YOR056C | NOB1 SGDID:S000005582, Chr XV from 431628-430249, reverse complement, Verified ORF, "Essential nuclear protein involved in proteasome maturation and synthesis of 40S ribosomal subunits; required for cleavage of the 20S pre-rRNA to generate the mature 18S rRNA" |
| 5079 | YOR057W | SGT1 SGDID:S000005583, Chr XV from 432188-433375, Verified ORF, "Probable cochaperone, regulates activity of Cyr1p (adenylyl cyclase); involved in assembly of the kinetochore complex, associates with the SCF (Skp1p/Cdc53p/F box protein) ubiquitin ligase complex" |
| 5080 | YOR058C | ASE1 SGDID:S000005584, Chr XV from 436347-433690, reverse complement, Verified ORF, "Mitotic spindle midzone localized microtubule-associated protein (MAP) family member; required for spindle elongation and stabilization; undergoes cell cycle-regulated degradation by anaphase promoting complex; potential Cdc28p substrate" |
| 5081 | YOR059C | YOR059C SGDID:S000005585, Chr XV from 440260-438908, reverse complement, Uncharacterized ORF, "Hypothetical protein" |
| 5082 | YOR060C | YOR060C SGDID:S000005586, Chr XV from 441165-440392, reverse complement, Uncharacterized ORF, "Protein of unknown function required for cell viability; deletion mutant harbors aberrant mitochondria" |
| 5083 | YOR061W | CKA2 SGDID:S000005587, Chr XV from 441536-442555, Verified ORF, "Alpha' catalytic subunit of casein kinase 2, a Ser/Thr protein kinase with roles in cell growth and proliferation; the holoenzyme also contains CKA1, CKB1 and CKB2, the many substrates include transcription factors and all RNA polymerases" |
| 5084 | YOR062C | YOR062C SGDID:S000005588, Chr XV from 443533-442727, reverse complement, Uncharacterized ORF, "Protein of unknown function; similar to YKR075Cp and Reg1p; expression regulated by glucose and Rgt1p; GFP-fusion protein is induced in response to the DNA-damaging agent MMS" |
| 5085 | YOR063W | RPL3 SGDID:S000005589, Chr XV from 444688-445851, Verified ORF, "Protein component of the large (60S) ribosomal subunit, has similarity to E. coli L3 and rat L3 ribosomal proteins; involved in the replication and maintenance of killer double stranded RNA virus" |
| 5086 | YOR064C | YNG1 SGDID:S000005590, Chr XV from 446740-446081, reverse complement, Verified ORF, "Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3, has similarity to the human tumor suppressor ING1" |
| 5087 | YOR065W | CYT1 SGDID:S000005591, Chr XV from 447441-448370, Verified ORF, "Cytochrome c1, component of the mitochondrial respiratory chain; expression is regulated by the heme-activated, glucose-repressed Hap2p/3p/4p/5p CCAAT-binding complex" |
| 5088 | YOR066W | MSA1 SGDID:S000005592, Chr XV from 449438-451327, Uncharacterized ORF, "Activator of G1-specific transcription factors, MBF and SBF, that regulates both the timing of G1-specific gene transcription, and cell cycle initiation; potential Cdc28p substrate" |
| 5089 | YOR067C | ALG8 SGDID:S000005593, Chr XV from 453464-451731, reverse complement, Verified ORF, "Glucosyl transferase, involved in N-linked glycosylation; adds glucose to the dolichol-linked oligosaccharide precursor prior to transfer to protein during lipid-linked oligosaccharide biosynthesis; similar to Alg6p" |
| 5090 | YOR068C | VAM10 SGDID:S000005594, Chr XV from 454215-453871, reverse complement, Verified ORF, "Protein involved in vacuole morphogenesis; acts at an early step of homotypic vacuole fusion that is required for vacuole tethering" |
| 5091 | YOR069W | VPS5 SGDID:S000005595, Chr XV from 453770-455797, Verified ORF, "Nexin-1 homolog required for localizing membrane proteins from a prevacuolar/late endosomal compartment back to the late Golgi apparatus; structural component of the retromer membrane coat complex; forms a retromer subcomplex with Vps17p" |
| 5092 | YOR070C | GYP1 SGDID:S000005596, Chr XV from 457822-455909, reverse complement, Verified ORF, "Cis-golgi GTPase-activating protein (GAP) for the Rab family members Ypt1p (in vivo) and for Ypt1p, Sec4p, Ypt7p, and Ypt51p (in vitro); involved in vesicle docking and fusion" |
| 5093 | YOR071C | NRT1 SGDID:S000005597, Chr XV from 461278-459482, reverse complement, Verified ORF, "High-affinity nicotinamide riboside transporter; also transports thiamine with low affinity; shares sequence similarity with Thi7p and Thi72p; proposed to be involved in 5-fluorocytosine sensitivity" |
| 5094 | YOR072W-B | YOR072W-B SGDID:S000028516, Chr XV from 464471-464632, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 5095 | YOR073W | SGO1 SGDID:S000005599, Chr XV from 464773-466545, Verified ORF, "Component of the spindle checkpoint, involved in sensing lack of tension on mitotic chromosomes; protects centromeric Rec8p at meiosis I; required for accurate chromosomal segregation at meiosis II and for mitotic chromosome stability" |
| 5096 | YOR074C | CDC21 SGDID:S000005600, Chr XV from 467591-466677, reverse complement, Verified ORF, "Thymidylate synthase, required for de novo biosynthesis of pyrimidine deoxyribonucleotides; expression is induced at G1/S" |
| 5097 | YOR075W | UFE1 SGDID:S000005601, Chr XV from 468214-469254, Verified ORF, "t-SNARE required for ER membrane fusion and vesicular traffic, integral membrane protein that constitutes with Sec20p and Use1p the trimeric acceptor for R/v-SNAREs on Golgi-derived vesicles at the ER; part of Dsl1p complex" |
| 5098 | YOR076C | SKI7 SGDID:S000005602, Chr XV from 471622-469379, reverse complement, Verified ORF, "Putative GTPase that mediates interactions via its N-terminus between the exosome and Ski complex (Ski2p, Ski3p, Ski8p) which operate in the 3'-to-5' mRNA-decay pathway; cytoplasmic protein required for degrading nonstop mRNAs" |
| 5099 | YOR077W | RTS2 SGDID:S000005603, Chr XV from 471901-472599, Verified ORF, "Basic zinc-finger protein, similar to human and mouse Kin17 proteins which are chromatin-associated proteins involved in UV response and DNA replication" |
| 5100 | YOR078W | BUD21 SGDID:S000005604, Chr XV from 472727-473371, Verified ORF, "Component of small ribosomal subunit (SSU) processosome that contains U3 snoRNA; originally isolated as bud-site selection mutant that displays a random budding pattern" |
| 5101 | YOR079C | ATX2 SGDID:S000005605, Chr XV from 474418-473477, reverse complement, Verified ORF, "Golgi membrane protein involved in manganese homeostasis; overproduction suppresses the sod1 (copper, zinc superoxide dismutase) null mutation" |
| 5102 | YOR080W | DIA2 SGDID:S000005606, Chr XV from 474554-476794, Verified ORF, "Origin-binding F-box protein that forms an SCF ubiquitin ligase complex with Skp1p and Cdc53p; plays a role in DNA replication, involved in invasive and pseudohyphal growth" |
| 5103 | YOR081C | TGL5 SGDID:S000005607, Chr XV from 479190-476941, reverse complement, Verified ORF, "Triacylglycerol lipase involved in TAG mobilization; localizes to lipid particles; potential Cdc28p substrate" |
| 5104 | YOR083W | WHI5 SGDID:S000005609, Chr XV from 479535-480422, Verified ORF, "Repressor of G1 transcription that binds to SCB binding factor (SBF) at SCB target promoters in early G1; phosphorylation of Whi5p by the CDK, Cln3p/Cdc28p relieves repression and promoter binding by Whi5; periodically expressed in G1" |
| 5105 | YOR084W | LPX1 SGDID:S000005610, Chr XV from 480589-481752, Verified ORF, "Oleic acid-inducible, peroxisomal matrix localized lipase; transcriptionally activated by Yrm1p along with genes involved in multidrug resistance; peroxisomal import is dependent on the PTS1 receptor, Pex5p and on self-interaction" |
| 5106 | YOR085W | OST3 SGDID:S000005611, Chr XV from 482035-483087, Verified ORF, "Gamma subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins; Ost3p is important for N-glycosylation of a subset of proteins" |
| 5107 | YOR086C | TCB1 SGDID:S000005612, Chr XV from 486781-483221, reverse complement, Verified ORF, "Lipid-binding protein containing three calcium and lipid binding domains; non-tagged protein localizes to mitochondria and GFP-fusion protein localizes to the cell periphery; C-termini of Tcb1p, Tcb2p and Tcb3p interact" |
| 5108 | YOR087W | YVC1 SGDID:S000005613, Chr XV from 487709-489736, Verified ORF, "Vacuolar cation channel, mediates release of Ca(2+) from the vacuole in response to hyperosmotic shock" |
| 5109 | YOR089C | VPS21 SGDID:S000005615, Chr XV from 490830-490198, reverse complement, Verified ORF, "GTPase required for transport during endocytosis and for correct sorting of vacuolar hydrolases; localized in endocytic intermediates; detected in mitochondria; geranylgeranylation required for membrane association; mammalian Rab5 homolog" |
| 5110 | YOR090C | PTC5 SGDID:S000005616, Chr XV from 492843-491125, reverse complement, Verified ORF, "Mitochondrial type 2C protein phosphatase involved in regulation of pyruvate dehydrogenase activity by dephosphorylating the ser-133 residue of the Pda1p subunit; acts in concert with kinases Pkp1p and Pkp2p and phosphatase Ptc6p" |
| 5111 | YOR091W | TMA46 SGDID:S000005617, Chr XV from 493434-494471, Verified ORF, "Protein of unknown function that associates with ribosomes; interacts with GTPase Rbg1p" |
| 5112 | YOR092W | ECM3 SGDID:S000005618, Chr XV from 495128-496969, Verified ORF, "Non-essential protein of unknown function; involved in signal transduction and the genotoxic response; induced rapidly in response to treatment with 8-methoxypsoralen and UVA irradiation" |
| 5113 | YOR093C | YOR093C SGDID:S000005619, Chr XV from 502453-497507, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; deletion causes sensitivity to unfolded protein response-inducing agents" |
| 5114 | YOR094W | ARF3 SGDID:S000005620, Chr XV from 502796-503347, Verified ORF, "Glucose-repressible ADP-ribosylation factor, GTPase of the Ras superfamily involved in development of polarity" |
| 5115 | YOR095C | RKI1 SGDID:S000005621, Chr XV from 504329-503553, reverse complement, Verified ORF, "Ribose-5-phosphate ketol-isomerase, catalyzes the interconversion of ribose 5-phosphate and ribulose 5-phosphate in the pentose phosphate pathway; participates in pyridoxine biosynthesis" |
| 5116 | YOR096W | RPS7A SGDID:S000005622, Chr XV from 505795-505938,506340-506768, Verified ORF, "Protein component of the small (40S) ribosomal subunit, nearly identical to Rps7Bp; interacts with Kti11p; deletion causes hypersensitivity to zymocin; has similarity to rat S7 and Xenopus S8 ribosomal proteins" |
| 5117 | YOR097C | YOR097C SGDID:S000005623, Chr XV from 507506-506979, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified as interacting with Hsp82p in a high-throughput two-hybrid screen; YOR097C is not an essential gene" |
| 5118 | YOR098C | NUP1 SGDID:S000005624, Chr XV from 511179-507949, reverse complement, Verified ORF, "Nuclear pore complex (NPC) subunit, involved in protein import/export and in export of RNAs, possible karyopherin release factor that accelerates release of karyopherin-cargo complexes after transport across NPC; potential Cdc28p substrate" |
| 5119 | YOR099W | KTR1 SGDID:S000005625, Chr XV from 511826-513007, Verified ORF, "Alpha-1,2-mannosyltransferase involved in O- and N-linked protein glycosylation; type II membrane protein; member of the KRE2/MNT1 mannosyltransferase family" |
| 5120 | YOR100C | CRC1 SGDID:S000005626, Chr XV from 514279-513296, reverse complement, Verified ORF, "Mitochondrial inner membrane carnitine transporter, required for carnitine-dependent transport of acetyl-CoA from peroxisomes to mitochondria during fatty acid beta-oxidation" |
| 5121 | YOR101W | RAS1 SGDID:S000005627, Chr XV from 515245-516174, Verified ORF, "GTPase involved in G-protein signaling in the adenylate cyclase activating pathway, plays a role in cell proliferation; localized to the plasma membrane; homolog of mammalian RAS proto-oncogenes" |
| 5122 | YOR103C | OST2 SGDID:S000005629, Chr XV from 516842-516450, reverse complement, Verified ORF, "Epsilon subunit of the oligosaccharyltransferase complex of the ER lumen, which catalyzes asparagine-linked glycosylation of newly synthesized proteins" |
| 5123 | YOR104W | PIN2 SGDID:S000005630, Chr XV from 517643-518491, Verified ORF, "Protein that induces appearance of [PIN+] prion when overproduced" |
| 5124 | YOR106W | VAM3 SGDID:S000005632, Chr XV from 519122-519973, Verified ORF, "Syntaxin-related protein required for vacuolar assembly; functions with Vam7p in vacuolar protein trafficking; member of the syntaxin family of proteins" |
| 5125 | YOR107W | RGS2 SGDID:S000005633, Chr XV from 521354-522283, Verified ORF, "Negative regulator of glucose-induced cAMP signaling; directly activates the GTPase activity of the heterotrimeric G protein alpha subunit Gpa2p" |
| 5126 | YOR108W | LEU9 SGDID:S000005634, Chr XV from 523028-524842, Verified ORF, "Alpha-isopropylmalate synthase II (2-isopropylmalate synthase), catalyzes the first step in the leucine biosynthesis pathway; the minor isozyme, responsible for the residual alpha-IPMS activity detected in a leu4 null mutant" |
| 5127 | YOR109W | INP53 SGDID:S000005635, Chr XV from 525279-528602, Verified ORF, "Polyphosphatidylinositol phosphatase, dephosphorylates multiple phosphatidylinositols; involved in trans Golgi network-to-early endosome pathway; hyperosmotic stress causes translocation to actin patches; contains Sac1 and 5-ptase domains" |
| 5128 | YOR110W | TFC7 SGDID:S000005636, Chr XV from 528942-530249, Verified ORF, "One of six subunits of the RNA polymerase III transcription initiation factor complex (TFIIIC); part of the TauA globular domain of TFIIIC that binds DNA at the BoxA promoter sites of tRNA and similar genes" |
| 5129 | YOR111W | YOR111W SGDID:S000005637, Chr XV from 530430-531128, Uncharacterized ORF, "Putative protein of unknown function" |
| 5130 | YOR112W | CEX1 SGDID:S000005638, Chr XV from 531509-533794, Verified ORF, "Cytoplasmic component of the nuclear aminoacylation-dependent tRNA export pathway; interacts with nuclear pore component Nup116p; copurifies with tRNA export receptors Los1p and Msn5p, as well as eIF-1a and the RAN GTPase Gsp1p" |
| 5131 | YOR113W | AZF1 SGDID:S000005639, Chr XV from 534076-536820, Verified ORF, "Zinc-finger transcription factor, involved in induction of CLN3 transcription in response to glucose; genetic and physical interactions indicate a possible role in mitochondrial transcription or genome maintenance" |
| 5132 | YOR114W | YOR114W SGDID:S000005640, Chr XV from 537571-538455, Uncharacterized ORF, "Putative protein of unknown function; null mutant is viable" |
| 5133 | YOR115C | TRS33 SGDID:S000005641, Chr XV from 539466-538660, reverse complement, Verified ORF, "One of 10 subunits of the transport protein particle (TRAPP) complex of the cis-Golgi which mediates vesicle docking and fusion; involved in endoplasmic reticulum (ER) to Golgi membrane traffic" |
| 5134 | YOR116C | RPO31 SGDID:S000005642, Chr XV from 544146-539764, reverse complement, Verified ORF, "RNA polymerase III subunit C160, part of core enzyme; similar to bacterial beta-prime subunit" |
| 5135 | YOR117W | RPT5 SGDID:S000005643, Chr XV from 545030-546334, Verified ORF, "One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; recruited to the GAL1-10 promoter region upon induction of transcription" |
| 5136 | YOR118W | YOR118W SGDID:S000005644, Chr XV from 546858-548561, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; null mutation suppresses cdc13-1 temperature sensitivity" |
| 5137 | YOR119C | RIO1 SGDID:S000005645, Chr XV from 550247-548793, reverse complement, Verified ORF, "Essential serine kinase involved in cell cycle progression and processing of the 20S pre-rRNA into mature 18S rRNA" |
| 5138 | YOR120W | GCY1 SGDID:S000005646, Chr XV from 551115-552053, Verified ORF, "Putative NADP(+) coupled glycerol dehydrogenase, proposed to be involved in an alternative pathway for glycerol catabolism; member of the aldo-keto reductase (AKR) family" |
| 5139 | YOR122C | PFY1 SGDID:S000005648, Chr XV from 552888-552876,552666-552299, reverse complement, Verified ORF, "Profilin, actin- and phosphatidylinositol 4,5-bisphosphate-binding protein, involved in cytoskeleton organization, required for normal timing of actin polymerization in response to thermal stress; localizes to plasma membrane and cytosol" |
| 5140 | YOR123C | LEO1 SGDID:S000005649, Chr XV from 554571-553177, reverse complement, Verified ORF, "Component of the Paf1 complex, which associates with RNA polymerase II and is involved in histone methylation; plays a role in regulating Ty1 transposition" |
| 5141 | YOR124C | UBP2 SGDID:S000005650, Chr XV from 558643-554825, reverse complement, Verified ORF, "Ubiquitin-specific protease that removes ubiquitin from ubiquitinated proteins, cleaves at the C terminus of ubiquitin fusions; capable of cleaving polyubiquitin and possesses isopeptidase activity" |
| 5142 | YOR125C | CAT5 SGDID:S000005651, Chr XV from 559732-559031, reverse complement, Verified ORF, "Protein required for ubiquinone (Coenzyme Q) biosynthesis; localizes to the matrix face of the mitochondrial inner membrane in a large complex with ubiquinone biosynthetic enzymes; required for gluconeogenic gene activation" |
| 5143 | YOR126C | IAH1 SGDID:S000005652, Chr XV from 560678-559962, reverse complement, Verified ORF, "Isoamyl acetate-hydrolyzing esterase, required in balance with alcohol acetyltransferase to maintain optimal amounts of isoamyl acetate, which is particularly important in sake brewing" |
| 5144 | YOR127W | RGA1 SGDID:S000005653, Chr XV from 561171-564194, Verified ORF, "GTPase-activating protein for the polarity-establishment protein Cdc42p; implicated in control of septin organization, pheromone response, and haploid invasive growth" |
| 5145 | YOR128C | ADE2 SGDID:S000005654, Chr XV from 566192-564477, reverse complement, Verified ORF, "Phosphoribosylaminoimidazole carboxylase, catalyzes a step in the 'de novo' purine nucleotide biosynthetic pathway; red pigment accumulates in mutant cells deprived of adenine" |
| 5146 | YOR129C | AFI1 SGDID:S000005655, Chr XV from 569559-566878, reverse complement, Verified ORF, "Arf3p polarization-specific docking factor, required for the polarized distribution of the ADP-ribosylation factor, Arf3p; participates in polarity development and maintenance of a normal haploid budding pattern; interacts with Cnm7p" |
| 5147 | YOR130C | ORT1 SGDID:S000005656, Chr XV from 570808-569930, reverse complement, Verified ORF, "Ornithine transporter of the mitochondrial inner membrane, exports ornithine from mitochondria as part of arginine biosynthesis; human ortholog is associated with hyperammonaemia-hyperornithinaemia-homocitrullinuria (HHH) syndrome" |
| 5148 | YOR131C | YOR131C SGDID:S000005657, Chr XV from 572839-572183, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; non-essential gene" |
| 5149 | YOR132W | VPS17 SGDID:S000005658, Chr XV from 573176-574831, Verified ORF, "Subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde protein transport; peripheral membrane protein that assembles onto the membrane with Vps5p to promote vesicle formation" |
| 5150 | YOR133W | EFT1 SGDID:S000005659, Chr XV from 575099-577627, Verified ORF, "Elongation factor 2 (EF-2), also encoded by EFT2; catalyzes ribosomal translocation during protein synthesis; contains diphthamide, the unique posttranslationally modified histidine residue specifically ADP-ribosylated by diphtheria toxin" |
| 5151 | YOR134W | BAG7 SGDID:S000005660, Chr XV from 578565-579794, Verified ORF, "Rho GTPase activating protein (RhoGAP), stimulates the intrinsic GTPase activity of Rho1p, which plays a role in actin cytoskeleton organization and control of cell wall synthesis; structurally and functionally related to Sac7p" |
| 5152 | YOR136W | IDH2 SGDID:S000005662, Chr XV from 580251-581360, Verified ORF, "Subunit of mitochondrial NAD(+)-dependent isocitrate dehydrogenase, which catalyzes the oxidation of isocitrate to alpha-ketoglutarate in the TCA cycle; phosphorylated" |
| 5153 | YOR137C | SIA1 SGDID:S000005663, Chr XV from 583682-581814, reverse complement, Verified ORF, "Protein of unassigned function involved in activation of the Pma1p plasma membrane H+-ATPase by glucose" |
| 5154 | YOR138C | RUP1 SGDID:S000005664, Chr XV from 586325-584310, reverse complement, Verified ORF, "Protein involved in regulation of Rsp5p, which is an essential HECT ubiquitin ligase; required for binding of Rsp5p to Ubp2p; contains an UBA domain" |
| 5155 | YOR140W | SFL1 SGDID:S000005666, Chr XV from 586982-589282, Verified ORF, "Transcriptional repressor and activator; involved in repression of flocculation-related genes, and activation of stress responsive genes; negatively regulated by cAMP-dependent protein kinase A subunit Tpk2p" |
| 5156 | YOR141C | ARP8 SGDID:S000005667, Chr XV from 592588-589943, reverse complement, Verified ORF, "Nuclear actin-related protein involved in chromatin remodeling, component of chromatin-remodeling enzyme complexes" |
| 5157 | YOR142W | LSC1 SGDID:S000005668, Chr XV from 593058-594047, Verified ORF, "Alpha subunit of succinyl-CoA ligase, which is a mitochondrial enzyme of the TCA cycle that catalyzes the nucleotide-dependent conversion of succinyl-CoA to succinate; phosphorylated" |
| 5158 | YOR142W-A | YOR142W-A SGDID:S000007351, Chr XV from 595113-596435, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 5159 | YOR142W-B | YOR142W-B SGDID:S000007352, Chr XV from 595113-596417,596419-600381, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 5160 | YOR143C | THI80 SGDID:S000005669, Chr XV from 602343-601384, reverse complement, Verified ORF, "Thiamine pyrophosphokinase, phosphorylates thiamine to produce the coenzyme thiamine pyrophosphate (thiamine diphosphate)" |
| 5161 | YOR144C | ELG1 SGDID:S000005670, Chr XV from 605093-602718, reverse complement, Verified ORF, "Protein required for S phase progression and telomere homeostasis, forms an alternative replication factor C complex important for DNA replication and genome integrity; involved in homologous recombination-mediated DNA repair" |
| 5162 | YOR145C | PNO1 SGDID:S000005671, Chr XV from 606172-605348, reverse complement, Verified ORF, "Essential nucleolar protein required for pre-18S rRNA processing, interacts with Dim1p, an 18S rRNA dimethyltransferase, and also with Nob1p, which is involved in proteasome biogenesis; contains a KH domain" |
| 5163 | YOR147W | MDM32 SGDID:S000005673, Chr XV from 606608-608476, Verified ORF, "Mitochondrial inner membrane protein with similarity to Mdm31p, required for normal mitochondrial morphology and inheritance; interacts genetically with MMM1, MDM10, MDM12, and MDM34" |
| 5164 | YOR148C | SPP2 SGDID:S000005674, Chr XV from 609198-608641, reverse complement, Verified ORF, "Essential protein that promotes the first step of splicing and is required for the final stages of spliceosome maturation; interacts with Prp2p, which may release Spp2p from the spliceosome following the first cleavage reaction" |
| 5165 | YOR149C | SMP3 SGDID:S000005675, Chr XV from 611389-609839, reverse complement, Verified ORF, "Alpha 1,2-mannosyltransferase involved in glycosyl phosphatidyl inositol (GPI) biosynthesis; required for addition of the fourth, side branching mannose to the GPI core structure" |
| 5166 | YOR150W | MRPL23 SGDID:S000005676, Chr XV from 612000-612491, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 5167 | YOR151C | RPB2 SGDID:S000005677, Chr XV from 616672-612998, reverse complement, Verified ORF, "RNA polymerase II second largest subunit B150, part of central core; similar to bacterial beta subunit" |
| 5168 | YOR152C | YOR152C SGDID:S000005678, Chr XV from 618289-617519, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; has no similarity to any known protein; YOR152C is not an essential gene" |
| 5169 | YOR153W | PDR5 SGDID:S000005679, Chr XV from 619841-624376, Verified ORF, "Plasma membrane ATP-binding cassette (ABC) transporter, short-lived multidrug transporter actively regulated by Pdr1p; also involved in steroid transport, cation resistance, and cellular detoxification during exponential growth" |
| 5170 | YOR154W | SLP1 SGDID:S000005680, Chr XV from 624730-626493, Uncharacterized ORF, "Integral membrane protein of unknown function; member of the SUN-like family of proteins" |
| 5171 | YOR155C | ISN1 SGDID:S000005681, Chr XV from 627981-626629, reverse complement, Verified ORF, "Inosine 5'-monophosphate (IMP)-specific 5'-nucleotidase, catalyzes the breakdown of IMP to inosine, does not show similarity to known 5'-nucleotidases from other organisms" |
| 5172 | YOR156C | NFI1 SGDID:S000005682, Chr XV from 630541-628361, reverse complement, Verified ORF, "SUMO ligase, catalyzes the covalent attachment of SUMO (Smt3p) to proteins; involved in maintenance of proper telomere length" |
| 5173 | YOR157C | PUP1 SGDID:S000005683, Chr XV from 631752-630967, reverse complement, Verified ORF, "Endopeptidase with trypsin-like activity that cleaves after basic residues; beta 2 subunit of 20S proteasome, synthesized as a proprotein before being proteolytically processed for assembly into 20S particle; human homolog is subunit Z" |
| 5174 | YOR158W | PET123 SGDID:S000005684, Chr XV from 632165-633121, Verified ORF, "Mitochondrial ribosomal protein of the small subunit; PET123 exhibits genetic interactions with PET122, which encodes a COX3 mRNA-specific translational activator" |
| 5175 | YOR159C | SME1 SGDID:S000005685, Chr XV from 633567-633283, reverse complement, Verified ORF, "Core Sm protein Sm E; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Smx3p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm E" |
| 5176 | YOR160W | MTR10 SGDID:S000005686, Chr XV from 633840-636758, Verified ORF, "Nuclear import receptor, mediates the nuclear localization of proteins involved in mRNA-nucleus export; promotes dissociation of mRNAs from the nucleus-cytoplasm mRNA shuttling protein Npl3p" |
| 5177 | YOR161C | PNS1 SGDID:S000005687, Chr XV from 638559-636940, reverse complement, Verified ORF, "Protein of unknown function; has similarity to Torpedo californica tCTL1p, which is postulated to be a choline transporter, neither null mutation nor overexpression affects choline transport" |
| 5178 | YOR161C-C | YOR161C-C SGDID:S000028712, Chr XV from 639268-639122, reverse complement, Uncharacterized ORF, "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 5179 | YOR162C | YRR1 SGDID:S000005688, Chr XV from 641993-639561, reverse complement, Verified ORF, "Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrm1p, acting on an overlapping set of target genes" |
| 5180 | YOR163W | DDP1 SGDID:S000005689, Chr XV from 642742-643308, Verified ORF, "Polyphosphate phosphatase; hydrolyzes diphosphorylated inositol polyphosphates and diadenosine polyphosphates; has high specificity for diadenosine hexa- and pentaphosphates; member of the MutT family of nucleotide hydrolases" |
| 5181 | YOR164C | YOR164C SGDID:S000005690, Chr XV from 644333-643395, reverse complement, Verified ORF, "Protein of unknown function; highly conserved across species and homologous to human gene C7orf20; interacts with Mdy2p" |
| 5182 | YOR165W | SEY1 SGDID:S000005691, Chr XV from 644567-646897, Verified ORF, "Protein of unknown function, contains two predicted GTP-binding motifs GXXXXGKS and DXXG near the N-terminus, homolog of the Arabidopsis gene RHD3 (Root Hair Defective)" |
| 5183 | YOR166C | SWT1 SGDID:S000005692, Chr XV from 648503-647127, reverse complement, Verified ORF, "Protein of unknown function; involved in transcription associated process; interacts genetically and physically with the TREX complex and RNA polymerase II; contains a PINc domain (PilT N terminus); localizes in the nucleus" |
| 5184 | YOR167C | RPS28A SGDID:S000005693, Chr XV from 649008-648805, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps28Bp and has similarity to rat S28 ribosomal protein" |
| 5185 | YOR168W | GLN4 SGDID:S000005694, Chr XV from 649304-651733, Verified ORF, "Glutamine tRNA synthetase, monomeric class I tRNA synthetase that catalyzes the specific glutaminylation of tRNA(Glu); N-terminal domain proposed to be involved in enzyme-tRNA interactions" |
| 5186 | YOR171C | LCB4 SGDID:S000005697, Chr XV from 653885-652011, reverse complement, Verified ORF, "Sphingoid long-chain base kinase, responsible for synthesis of long-chain base phosphates, which function as signaling molecules, regulates synthesis of ceramide from exogenous long-chain bases, localizes to the Golgi and late endosomes" |
| 5187 | YOR172W | YRM1 SGDID:S000005698, Chr XV from 654211-656571, Verified ORF, "Zn2-Cys6 zinc-finger transcription factor that activates genes involved in multidrug resistance; paralog of Yrr1p, acting on an overlapping set of target genes" |
| 5188 | YOR173W | DCS2 SGDID:S000005699, Chr XV from 657265-658326, Verified ORF, "Non-essential, stress induced regulatory protein containing a HIT (histidine triad) motif; modulates m7G-oligoribonucleotide metabolism; inhibits Dcs1p; regulated by Msn2p, Msn4p, and the Ras-cAMP-cAPK signaling pathway, similar to Dcs1p." |
| 5189 | YOR174W | MED4 SGDID:S000005700, Chr XV from 658748-659602, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation" |
| 5190 | YOR175C | ALE1 SGDID:S000005701, Chr XV from 661675-659816, reverse complement, Verified ORF, "Lysophospholipid acyltransferase, partially redundant with Slc1p; part of MBOAT family of membrane-bound O-acyltransferases; key component of Lands cycle; may have role in fatty acid exchange at sn-2 position of mature glycerophospholipids" |
| 5191 | YOR176W | HEM15 SGDID:S000005702, Chr XV from 662402-663583, Verified ORF, "Ferrochelatase, a mitochondrial inner membrane protein, catalyzes the insertion of ferrous iron into protoporphyrin IX, the eighth and final step in the heme biosynthetic pathway" |
| 5192 | YOR177C | MPC54 SGDID:S000005703, Chr XV from 667180-665786, reverse complement, Verified ORF, "Component of the meiotic outer plaque, a membrane-organizing center which is assembled on the cytoplasmic face of the spindle pole body during meiosis II and triggers the formation of the prospore membrane; potential Cdc28p substrate" |
| 5193 | YOR178C | GAC1 SGDID:S000005704, Chr XV from 670242-667861, reverse complement, Verified ORF, "Regulatory subunit for Glc7p type-1 protein phosphatase (PP1), tethers Glc7p to Gsy2p glycogen synthase, binds Hsf1p heat shock transcription factor, required for induction of some HSF-regulated genes under heat shock" |
| 5194 | YOR179C | SYC1 SGDID:S000005705, Chr XV from 672412-671846, reverse complement, Verified ORF, "Subunit of the APT subcomplex of cleavage and polyadenylation factor, may have a role in 3' end formation of both polyadenylated and non-polyadenylated RNAs" |
| 5195 | YOR180C | DCI1 SGDID:S000005706, Chr XV from 675168-674353, reverse complement, Verified ORF, "Peroxisomal delta(3,5)-delta(2,4)-dienoyl-CoA isomerase, involved in fatty acid metabolism, contains peroxisome targeting signals at amino and carboxy termini" |
| 5196 | YOR181W | LAS17 SGDID:S000005707, Chr XV from 675940-677841, Verified ORF, "Actin assembly factor, activates the Arp2/3 protein complex that nucleates branched actin filaments; localizes with the Arp2/3 complex to actin patches; homolog of the human Wiskott-Aldrich syndrome protein (WASP)" |
| 5197 | YOR182C | RPS30B SGDID:S000005708, Chr XV from 678794-678792,678380-678192, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps30Ap and has similarity to rat S30 ribosomal protein" |
| 5198 | YOR183W | FYV12 SGDID:S000005709, Chr XV from 678873-679262, Uncharacterized ORF, "Protein of unknown function, required for survival upon exposure to K1 killer toxin" |
| 5199 | YOR184W | SER1 SGDID:S000005710, Chr XV from 679358-680545, Verified ORF, "3-phosphoserine aminotransferase, catalyzes the formation of phosphoserine from 3-phosphohydroxypyruvate, required for serine and glycine biosynthesis; regulated by the general control of amino acid biosynthesis mediated by Gcn4p" |
| 5200 | YOR185C | GSP2 SGDID:S000005711, Chr XV from 682107-681445, reverse complement, Verified ORF, "GTP binding protein (mammalian Ranp homolog) involved in the maintenance of nuclear organization, RNA processing and transport; interacts with Kap121p, Kap123p and Pdr6p (karyophilin betas); Gsp1p homolog that is not required for viability" |
| 5201 | YOR186W | YOR186W SGDID:S000005712, Chr XV from 683112-683546, Uncharacterized ORF, "Putative protein of unknown function; proper regulation of expression during heat stress is sphingolipid-dependent" |
| 5202 | YOR187W | TUF1 SGDID:S000005713, Chr XV from 684031-685344, Verified ORF, "Mitochondrial translation elongation factor Tu; comprises both GTPase and guanine nucleotide exchange factor activities, while these activities are found in separate proteins in S. pombe and humans" |
| 5203 | YOR188W | MSB1 SGDID:S000005714, Chr XV from 685768-689181, Verified ORF, "Protein involved in positive regulation of both 1,3-beta-glucan synthesis and the Pkc1p-MAPK pathway, potential Cdc28p substrate; multicopy suppressor of temperature-sensitive mutations in CDC24 and CDC42, and of mutations in BEM4" |
| 5204 | YOR189W | IES4 SGDID:S000005715, Chr XV from 689625-689975, Verified ORF, "Component of the INO80 chromatiin remodeling complex and target of the Mec1p/Tel1p DNA damage signaling pathway; proposed to link chromatin remodeling to replication checkpoint responses" |
| 5205 | YOR190W | SPR1 SGDID:S000005716, Chr XV from 690696-692033, Verified ORF, "Sporulation-specific exo-1,3-beta-glucanase; contributes to ascospore thermoresistance" |
| 5206 | YOR191W | ULS1 SGDID:S000005717, Chr XV from 692476-697335, Verified ORF, "RING finger protein involved in proteolytic control of sumoylated substrates; interacts with SUMO (Smt3p); member of the SWI/SNF family of DNA-dependent ATPases; plays a role in antagonizing silencing during mating-type switching" |
| 5207 | YOR192C | THI72 SGDID:S000005718, Chr XV from 700568-698769, reverse complement, Verified ORF, "Transporter of thiamine or related compound; shares sequence similarity with Thi7p" |
| 5208 | YOR192C-A | YOR192C-A SGDID:S000007353, Chr XV from 709733-708417, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 5209 | YOR192C-B | YOR192C-B SGDID:S000007354, Chr XV from 709733-708441,708439-704420, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 5210 | YOR192C-C | YOR192C-C SGDID:S000028857, Chr XV from 704225-703989, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 5211 | YOR193W | PEX27 SGDID:S000005719, Chr XV from 710447-711577, Verified ORF, "Peripheral peroxisomal membrane protein involved in controlling peroxisome size and number, interacts with homologous protein Pex25p" |
| 5212 | YOR194C | TOA1 SGDID:S000005720, Chr XV from 712544-711684, reverse complement, Verified ORF, "TFIIA large subunit; involved in transcriptional activation, acts as antirepressor or as coactivator; homologous to largest and second largest subunits of human and Drosophila TFIIA" |
| 5213 | YOR195W | SLK19 SGDID:S000005721, Chr XV from 712867-715332, Verified ORF, "Kinetochore-associated protein required for normal segregation of chromosomes in meiosis and mitosis; component of the FEAR regulatory network, which promotes Cdc14p release from the nucleolus during anaphase; potential Cdc28p substrate" |
| 5214 | YOR196C | LIP5 SGDID:S000005722, Chr XV from 716838-715594, reverse complement, Verified ORF, "Protein involved in biosynthesis of the coenzyme lipoic acid, has similarity to E. coli lipoic acid synthase" |
| 5215 | YOR197W | MCA1 SGDID:S000005723, Chr XV from 717087-718385, Verified ORF, "Putative cysteine protease similar to mammalian caspases, involved in regulation of apoptosis upon hydrogen peroxide treatment" |
| 5216 | YOR198C | BFR1 SGDID:S000005724, Chr XV from 720066-718654, reverse complement, Verified ORF, "Component of mRNP complexes associated with polyribosomes; implicated in secretion and nuclear segregation; multicopy suppressor of BFA (Brefeldin A) sensitivity" |
| 5217 | YOR201C | MRM1 SGDID:S000005727, Chr XV from 721709-720471, reverse complement, Verified ORF, "Ribose methyltransferase that modifies a functionally critical, conserved nucleotide in mitochondrial 21S rRNA" |
| 5218 | YOR202W | HIS3 SGDID:S000005728, Chr XV from 721947-722609, Verified ORF, "Imidazoleglycerol-phosphate dehydratase, catalyzes the sixth step in histidine biosynthesis; mutations cause histidine auxotrophy and sensitivity to Cu, Co, and Ni salts; transcription is regulated by general amino acid control via Gcn4p" |
| 5219 | YOR204W | DED1 SGDID:S000005730, Chr XV from 722912-724726, Verified ORF, "ATP-dependent DEAD (Asp-Glu-Ala-Asp)-box RNA helicase, required for translation initiation of all yeast mRNAs; mutations in human DEAD-box DBY are a frequent cause of male infertility" |
| 5220 | YOR205C | YOR205C SGDID:S000005731, Chr XV from 727235-725565, reverse complement, Uncharacterized ORF, "Protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays decreased frequency of mitochondrial genome loss and severe growth defect in minimal glycerol media" |
| 5221 | YOR206W | NOC2 SGDID:S000005732, Chr XV from 727513-729645, Verified ORF, "Protein that forms a nucleolar complex with Mak21p that binds to 90S and 66S pre-ribosomes, as well as a nuclear complex with Noc3p that binds to 66S pre-ribosomes; both complexes mediate intranuclear transport of ribosomal precursors" |
| 5222 | YOR207C | RET1 SGDID:S000005733, Chr XV from 733458-730009, reverse complement, Verified ORF, "Second-largest subunit of RNA polymerase III, which is responsible for the transcription of tRNA and 5S RNA genes, and other low molecular weight RNAs" |
| 5223 | YOR208W | PTP2 SGDID:S000005734, Chr XV from 733926-736178, Verified ORF, "Phosphotyrosine-specific protein phosphatase involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; localized to the nucleus" |
| 5224 | YOR209C | NPT1 SGDID:S000005735, Chr XV from 737727-736438, reverse complement, Verified ORF, "Nicotinate phosphoribosyltransferase, acts in the salvage pathway of NAD+ biosynthesis; required for silencing at rDNA and telomeres and has a role in silencing at mating-type loci; localized to the nucleus" |
| 5225 | YOR210W | RPB10 SGDID:S000005736, Chr XV from 738321-738533, Verified ORF, "RNA polymerase subunit ABC10-beta, common to RNA polymerases I, II, and III" |
| 5226 | YOR211C | MGM1 SGDID:S000005737, Chr XV from 741570-738925, reverse complement, Verified ORF, "Mitochondrial GTPase related to dynamin, present in a complex containing Ugo1p and Fzo1p; required for normal morphology of cristae and for stability of Tim11p; homolog of human OPA1 involved in autosomal dominant optic atrophy" |
| 5227 | YOR212W | STE4 SGDID:S000005738, Chr XV from 742911-744182, Verified ORF, "G protein beta subunit, forms a dimer with Ste18p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste18p to dampen signaling; may recruit Rho1p to the polarized growth site during mating; contains WD40 repeats" |
| 5228 | YOR213C | SAS5 SGDID:S000005739, Chr XV from 745282-744536, reverse complement, Verified ORF, "Subunit of the SAS complex (Sas2p, Sas4p, Sas5p), which acetylates free histones and nucleosomes and regulates transcriptional silencing; stimulates Sas2p HAT activity" |
| 5229 | YOR214C | YOR214C SGDID:S000005740, Chr XV from 746304-745594, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YOR214C is not an essential gene" |
| 5230 | YOR215C | YOR215C SGDID:S000005741, Chr XV from 747283-746726, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic protein is detected in highly purified mitochondria in high-throughput studies; null mutant displays altered rate of mitochondrial loss and reduced growth rate in minimal glycerol media" |
| 5231 | YOR216C | RUD3 SGDID:S000005742, Chr XV from 748980-747526, reverse complement, Verified ORF, "Golgi matrix protein involved in the structural organization of the cis-Golgi; interacts genetically with COG3 and USO1" |
| 5232 | YOR217W | RFC1 SGDID:S000005743, Chr XV from 749302-751887, Verified ORF, "Subunit of heteropentameric Replication factor C (RF-C), which is a DNA binding protein and ATPase that acts as a clamp loader of the proliferating cell nuclear antigen (PCNA) processivity factor for DNA polymerases delta and epsilon" |
| 5233 | YOR219C | STE13 SGDID:S000005745, Chr XV from 755010-752215, reverse complement, Verified ORF, "Dipeptidyl aminopeptidase, Golgi integral membrane protein that cleaves on the carboxyl side of repeating -X-Ala- sequences, required for maturation of alpha factor, transcription is induced by a-factor" |
| 5234 | YOR220W | YOR220W SGDID:S000005746, Chr XV from 755329-756126, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS" |
| 5235 | YOR221C | MCT1 SGDID:S000005747, Chr XV from 757559-756477, reverse complement, Verified ORF, "Predicted malonyl-CoA:ACP transferase, putative component of a type-II mitochondrial fatty acid synthase that produces intermediates for phospholipid remodeling" |
| 5236 | YOR222W | ODC2 SGDID:S000005748, Chr XV from 758331-759254, Verified ORF, "Mitochondrial inner membrane transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for use in lysine and glutamate biosynthesis and in lysine catabolism" |
| 5237 | YOR223W | YOR223W SGDID:S000005749, Chr XV from 759783-760661, Uncharacterized ORF, "Putative protein of unknown function" |
| 5238 | YOR224C | RPB8 SGDID:S000005750, Chr XV from 761266-760826, reverse complement, Verified ORF, "RNA polymerase subunit ABC14.5, common to RNA polymerases I, II, and III" |
| 5239 | YOR226C | ISU2 SGDID:S000005752, Chr XV from 762085-761615, reverse complement, Verified ORF, "Conserved protein of the mitochondrial matrix, required for synthesis of mitochondrial and cytosolic iron-sulfur proteins, performs a scaffolding function in mitochondria during Fe/S cluster assembly; isu1 isu2 double mutant is inviable" |
| 5240 | YOR227W | YOR227W SGDID:S000005753, Chr XV from 762826-766566, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 5241 | YOR228C | YOR228C SGDID:S000005754, Chr XV from 767778-766870, reverse complement, Verified ORF, "Protein of unknown function, localized to the mitochondrial outer membrane" |
| 5242 | YOR229W | WTM2 SGDID:S000005755, Chr XV from 768410-769813, Verified ORF, "Transcriptional modulator involved in regulation of meiosis, silencing, and expression of RNR genes; involved in response to replication stress; contains WD repeats" |
| 5243 | YOR230W | WTM1 SGDID:S000005756, Chr XV from 770801-772114, Verified ORF, "Transcriptional modulator involved in regulation of meiosis, silencing, and expression of RNR genes; required for nuclear localization of the ribonucleotide reductase small subunit Rnr2p and Rnr4p; contains WD repeats" |
| 5244 | YOR231W | MKK1 SGDID:S000005757, Chr XV from 772602-774128, Verified ORF, "Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk2p" |
| 5245 | YOR232W | MGE1 SGDID:S000005758, Chr XV from 774574-775260, Verified ORF, "Protein of the mitochondrial matrix involved in protein import into mitochondria; acts as a cochaperone and a nucleotide release factor for Ssc1p; homolog of E. coli GrpE" |
| 5246 | YOR233W | KIN4 SGDID:S000005759, Chr XV from 775847-778249, Verified ORF, "Serine/threonine protein kinase that inhibits the mitotic exit network (MEN) when the spindle position checkpoint is activated; localized asymmetrically to mother cell cortex, spindle pole body and bud neck" |
| 5247 | YOR234C | RPL33B SGDID:S000005760, Chr XV from 779406-779388,778860-778556, reverse complement, Verified ORF, "Ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Ap and has similarity to rat L35a; rpl33b null mutant exhibits normal growth while rpl33a rpl33b double null mutant is inviable" |
| 5248 | YOR236W | DFR1 SGDID:S000005762, Chr XV from 780907-781542, Verified ORF, "Dihydrofolate reductase, part of the dTTP biosynthetic pathway, involved in folate metabolism, possibly required for mitochondrial function" |
| 5249 | YOR237W | HES1 SGDID:S000005763, Chr XV from 781995-783299, Verified ORF, "Protein implicated in the regulation of ergosterol biosynthesis; one of a seven member gene family with a common essential function and non-essential unique functions; similar to human oxysterol binding protein (OSBP)" |
| 5250 | YOR238W | YOR238W SGDID:S000005764, Chr XV from 783678-784589, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 5251 | YOR239W | ABP140 SGDID:S000005765, Chr XV from 784858-785688,785690-786745, Verified ORF, "Nonessential protein that binds actin filaments and localizes to actin patches and cables, has similarity to S-adenosylmethionine (AdoMet)-dependent methyltransferases" |
| 5252 | YOR241W | MET7 SGDID:S000005767, Chr XV from 786996-788642, Verified ORF, "Folylpolyglutamate synthetase, catalyzes extension of the glutamate chains of the folate coenzymes, required for methionine synthesis and for maintenance of mitochondrial DNA" |
| 5253 | YOR242C | SSP2 SGDID:S000005768, Chr XV from 789858-788743, reverse complement, Verified ORF, "Sporulation specific protein that localizes to the spore wall; required for sporulation at a point after meiosis II and during spore wall formation; SSP2 expression is induced midway in meiosis" |
| 5254 | YOR243C | PUS7 SGDID:S000005769, Chr XV from 792242-790212, reverse complement, Verified ORF, "Pseudouridine synthase, catalyzes pseudouridylation at position 35 in U2 snRNA, position 13 in cytoplasmic tRNAs, and position 35 in pre-tRNA(Tyr); Asp(256) mutation abolishes activity; conserved in archaea, some bacteria, and vertebrates" |
| 5255 | YOR244W | ESA1 SGDID:S000005770, Chr XV from 792532-793869, Verified ORF, "Histone acetyltransferase catalytic subunit of the native multisubunit complex (NuA4) that acetylates four conserved internal lysines of histone H4 N-terminal tail; required for cell cycle progression" |
| 5256 | YOR245C | DGA1 SGDID:S000005771, Chr XV from 795333-794077, reverse complement, Verified ORF, "Diacylglycerol acyltransferase, catalyzes the terminal step of triacylglycerol (TAG) formation, acylates diacylglycerol using acyl-CoA as an acyl donor, localized to lipid particles" |
| 5257 | YOR246C | YOR246C SGDID:S000005772, Chr XV from 796794-795802, reverse complement, Uncharacterized ORF, "Protein with similarity to oxidoreductases, found in lipid particles; required for replication of Brome mosaic virus in S. cerevisiae, which is a model system for studying replication of positive-strand RNA viruses in their natural hosts" |
| 5258 | YOR247W | SRL1 SGDID:S000005773, Chr XV from 797677-798309, Verified ORF, "Mannoprotein that exhibits a tight association with the cell wall, required for cell wall stability in the absence of GPI-anchored mannoproteins; has a high serine-threonine content; expression is induced in cell wall mutants" |
| 5259 | YOR249C | APC5 SGDID:S000005775, Chr XV from 800732-798675, reverse complement, Verified ORF, "Subunit of the Anaphase-Promoting Complex/Cyclosome (APC/C), which is a ubiquitin-protein ligase required for degradation of anaphase inhibitors, including mitotic cyclins, during the metaphase/anaphase transition" |
| 5260 | YOR250C | CLP1 SGDID:S000005776, Chr XV from 802308-800971, reverse complement, Verified ORF, "Subunit of cleavage factor I (CFI), involved in both the endonucleolyitc cleavage and polyadenylation steps of mRNA 3'-end maturation" |
| 5261 | YOR251C | YOR251C SGDID:S000005777, Chr XV from 803465-802551, reverse complement, Uncharacterized ORF, "Putative protein of unknown function with similarity to human thiosulfate sulfurtransferase, an enzyme that catalyzes the transfer of sulfur from thiosulfate to cyanide, forming sulfite and thiocyanate; YOR251C is a non-essential gene" |
| 5262 | YOR252W | TMA16 SGDID:S000005778, Chr XV from 803668-804204, Verified ORF, "Protein of unknown function that associates with ribosomes" |
| 5263 | YOR253W | NAT5 SGDID:S000005779, Chr XV from 804378-804908, Verified ORF, "Subunit of the N-terminal acetyltransferase NatA (Nat1p, Ard1p, Nat5p); N-terminally acetylates many proteins, which influences multiple processes such as the cell cycle, heat-shock resistance, mating, sporulation, and telomeric silencing" |
| 5264 | YOR254C | SEC63 SGDID:S000005780, Chr XV from 807024-805033, reverse complement, Verified ORF, "Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER" |
| 5265 | YOR255W | OSW1 SGDID:S000005781, Chr XV from 807272-808108, Verified ORF, "Protein involved in sporulation; required for the construction of the outer spore wall layers; required for proper localization of Spo14p" |
| 5266 | YOR256C | TRE2 SGDID:S000005782, Chr XV from 810683-808254, reverse complement, Verified ORF, "Protein that functions with Tre1p to regulate ubiquitylation and vacuolar degradation of the metal transporter Smf1p; has similarity to transferrin receptors; inviability of null mutant in systematic studies is due to proximity to CDC31" |
| 5267 | YOR257W | CDC31 SGDID:S000005783, Chr XV from 811008-811493, Verified ORF, "Calcium-binding component of the spindle pole body (SPB) half-bridge, required for SPB duplication in mitosis and meiosis II; homolog of mammalian centrin; binds multiubiquitinated proteins and is involved in proteasomal protein degradation" |
| 5268 | YOR258W | HNT3 SGDID:S000005784, Chr XV from 811671-812324, Verified ORF, "Member of the third branch of the histidine triad (HIT) superfamily of nucleotide-binding proteins; similar to Aprataxin, a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxia" |
| 5269 | YOR259C | RPT4 SGDID:S000005785, Chr XV from 813708-812395, reverse complement, Verified ORF, "One of six ATPases of the 19S regulatory particle of the 26S proteasome involved in the degradation of ubiquitinated substrates; required for spindle pole body duplication; localized mainly to the nucleus throughout the cell cycle" |
| 5270 | YOR260W | GCD1 SGDID:S000005786, Chr XV from 813984-815720, Verified ORF, "Gamma subunit of the translation initiation factor eIF2B, the guanine-nucleotide exchange factor for eIF2; activity subsequently regulated by phosphorylated eIF2; first identified as a negative regulator of GCN4 expression" |
| 5271 | YOR261C | RPN8 SGDID:S000005787, Chr XV from 816931-815915, reverse complement, Verified ORF, "Essential, non-ATPase regulatory subunit of the 26S proteasome; has similarity to the human p40 proteasomal subunit and to another S. cerevisiae regulatory subunit, Rpn11p" |
| 5272 | YOR262W | YOR262W SGDID:S000005788, Chr XV from 817291-818334, Verified ORF, "Protein of unknown function required for establishment of sister chromatid cohesion; contains an ATP/GTP binding site motif; similar to YLR243W and is highly conserved across species and homologous to human gene GPN2/ATPBD1B" |
| 5273 | YOR264W | DSE3 SGDID:S000005790, Chr XV from 818865-820157, Verified ORF, "Daughter cell-specific protein, may help establish daughter fate" |
| 5274 | YOR265W | RBL2 SGDID:S000005791, Chr XV from 820453-820773, Verified ORF, "Protein involved in microtubule morphogenesis, required for protection from excess free beta-tubulin; proposed to be involved the folding of beta-tubulin; similar to mouse beta-tubulin cofactor A" |
| 5275 | YOR266W | PNT1 SGDID:S000005792, Chr XV from 821022-822293, Verified ORF, "Mitochondrial integral inner membrane protein involved in membrane insertion of C-terminus of Cox2p, interacts genetically and physically with Cox18p; deletion mutant sensitive to the anti-Pneumocystis carinii drug pentamidine" |
| 5276 | YOR267C | HRK1 SGDID:S000005793, Chr XV from 824866-822587, reverse complement, Verified ORF, "Protein kinase implicated in activation of the plasma membrane H(+)-ATPase Pma1p in response to glucose metabolism; plays a role in ion homeostasis" |
| 5277 | YOR268C | YOR268C SGDID:S000005794, Chr XV from 825931-825533, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; sporulation is abnormal in homozygous diploid; YOR268C is not an essential gene" |
| 5278 | YOR269W | PAC1 SGDID:S000005795, Chr XV from 826384-827868, Verified ORF, "Protein involved in nuclear migration, part of the dynein/dynactin pathway; targets dynein to microtubule tips, which is necessary for sliding of microtubules along bud cortex; synthetic lethal with bni1; homolog of human LIS1" |
| 5279 | YOR270C | VPH1 SGDID:S000005796, Chr XV from 830573-828051, reverse complement, Verified ORF, "Subunit a of vacuolar-ATPase V0 domain, one of two isoforms (Vph1p and Stv1p); Vph1p is located in V-ATPase complexes of the vacuole while Stv1p is located in V-ATPase complexes of the Golgi and endosomes" |
| 5280 | YOR271C | FSF1 SGDID:S000005797, Chr XV from 832041-831058, reverse complement, Uncharacterized ORF, "Putative protein, predicted to be an alpha-isopropylmalate carrier; belongs to the sideroblastic-associated protein family; non-tagged protein is detected in purified mitochondria; likely to play a role in iron homeostasis" |
| 5281 | YOR272W | YTM1 SGDID:S000005798, Chr XV from 832812-834194, Verified ORF, "Constituent of 66S pre-ribosomal particles, required for maturation of the large ribosomal subunit" |
| 5282 | YOR273C | TPO4 SGDID:S000005799, Chr XV from 836430-834451, reverse complement, Verified ORF, "Polyamine transport protein, recognizes spermine, putrescine, and spermidine; localizes to the plasma membrane; member of the major facilitator superfamily" |
| 5283 | YOR274W | MOD5 SGDID:S000005800, Chr XV from 837673-838959, Verified ORF, "Delta 2-isopentenyl pyrophosphate:tRNA isopentenyl transferase, required for biosynthesis of the modified base isopentenyladenosine in mitochondrial and cytoplasmic tRNAs; gene is nuclear and encodes two isozymic forms" |
| 5284 | YOR275C | RIM20 SGDID:S000005801, Chr XV from 841068-839083, reverse complement, Verified ORF, "Protein involved in proteolytic activation of Rim101p in response to alkaline pH; PalA/AIP1/Alix family member; interaction with the ESCRT-III subunit Snf7p suggests a relationship between pH response and multivesicular body formation" |
| 5285 | YOR276W | CAF20 SGDID:S000005802, Chr XV from 841332-841817, Verified ORF, "Phosphoprotein of the mRNA cap-binding complex involved in translational control, repressor of cap-dependent translation initiation, competes with eIF4G for binding to eIF4E" |
| 5286 | YOR278W | HEM4 SGDID:S000005804, Chr XV from 842816-843643, Verified ORF, "Uroporphyrinogen III synthase, catalyzes the conversion of hydroxymethylbilane to uroporphyrinogen III, the fourth step in the heme biosynthetic pathway" |
| 5287 | YOR279C | RFM1 SGDID:S000005805, Chr XV from 844629-843697, reverse complement, Verified ORF, "DNA-binding protein required for vegetative repression of middle sporulation genes; specificity factor that directs the Hst1p histone deacetylase to some of the promoters regulated by Sum1p; involved in telomere maintenance" |
| 5288 | YOR280C | FSH3 SGDID:S000005806, Chr XV from 845791-844991, reverse complement, Verified ORF, "Serine hydrolase; sequence is similar to Fsh1p and Fsh2p" |
| 5289 | YOR281C | PLP2 SGDID:S000005807, Chr XV from 847128-846268, reverse complement, Verified ORF, "Essential protein with similarity to phosducins, which are G-protein regulators; lethality of null mutation is functionally complemented by expression of mouse phosducin-like protein MgcPhLP" |
| 5290 | YOR283W | YOR283W SGDID:S000005809, Chr XV from 847452-848144, Uncharacterized ORF, "Putative protein of unknown function with some similarity to GPM1/YKL152C, a phosphoglycerate mutase; YOR283W is not an essential gene" |
| 5291 | YOR284W | HUA2 SGDID:S000005810, Chr XV from 848477-849208, Verified ORF, "Cytoplasmic protein of unknown function; computational analysis of large-scale protein-protein interaction data suggests a possible role in actin patch assembly" |
| 5292 | YOR285W | YOR285W SGDID:S000005811, Chr XV from 849634-850053, Verified ORF, "Protein of unknown function, localized to the mitochondrial outer membrane" |
| 5293 | YOR286W | YOR286W SGDID:S000005812, Chr XV from 850279-850728, Uncharacterized ORF, "Protein of unknown function; non-tagged protein is detected in purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss and reduced growth rate in minimal glycerol media" |
| 5294 | YOR287C | YOR287C SGDID:S000005813, Chr XV from 851838-850936, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; may play a role in the ribosome and rRNA biosynthesis based on expression profiles and mutant phenotype" |
| 5295 | YOR288C | MPD1 SGDID:S000005814, Chr XV from 853076-852120, reverse complement, Verified ORF, "Member of the protein disulfide isomerase (PDI) family; interacts with and inhibits the chaperone activity of Cne1p; MPD1 overexpression in a pdi1 null mutant suppresses defects in Pdi1p functions such as carboxypeptidase Y maturation" |
| 5296 | YOR289W | YOR289W SGDID:S000005815, Chr XV from 853356-854111, Uncharacterized ORF, "Putative protein of unknown function; transcription induced by the unfolded protein response; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus" |
| 5297 | YOR290C | SNF2 SGDID:S000005816, Chr XV from 860257-855146, reverse complement, Verified ORF, "Catalytic subunit of the SWI/SNF chromatin remodeling complex involved in transcriptional regulation; contains DNA-stimulated ATPase activity; functions interdependently in transcriptional activation with Snf5p and Snf6p" |
| 5298 | YOR291W | YOR291W SGDID:S000005817, Chr XV from 861174-865592, Uncharacterized ORF, "Putative protein of unknown function; shares sequence similarity with the type V P-type ATPase Spf1p; YOR291W is not an essential protein" |
| 5299 | YOR292C | YOR292C SGDID:S000005818, Chr XV from 866581-865652, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the vacuole; YOR292C is not an essential gene" |
| 5300 | YOR293C-A | YOR293C-A SGDID:S000028858, Chr XV from 868146-867997, reverse complement, Uncharacterized ORF, "Identified by expression profiling and mass spectrometry" |
| 5301 | YOR293W | RPS10A SGDID:S000005819, Chr XV from 867097-867148,867586-867851, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps10Bp and has similarity to rat ribosomal protein S10" |
| 5302 | YOR294W | RRS1 SGDID:S000005820, Chr XV from 868339-868950, Verified ORF, "Essential protein that binds ribosomal protein L11 and is required for nuclear export of the 60S pre-ribosomal subunit during ribosome biogenesis; mouse homolog shows altered expression in Huntington's disease model mice" |
| 5303 | YOR295W | UAF30 SGDID:S000005821, Chr XV from 869207-869893, Verified ORF, "Subunit of UAF (upstream activation factor), which is an RNA polymerase I specific transcription stimulatory factor composed of Uaf30p, Rrn5p, Rrn9p, Rrn10p, histones H3 and H4; deletion decreases cellular growth rate" |
| 5304 | YOR296W | YOR296W SGDID:S000005822, Chr XV from 870201-874070, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; expressed during copper starvation; YOR296W is not an essential gene" |
| 5305 | YOR297C | TIM18 SGDID:S000005823, Chr XV from 875320-874742, reverse complement, Verified ORF, "Component of the mitochondrial Tim54p-Tim22p complex involved in insertion of polytopic proteins into the inner membrane; may function to stabilize the complex" |
| 5306 | YOR298C-A | MBF1 SGDID:S000007253, Chr XV from 877684-877229, reverse complement, Verified ORF, "Transcriptional coactivator that bridges the DNA-binding region of Gcn4p and TATA-binding protein Spt15p; suppressor of frameshift mutations" |
| 5307 | YOR298W | MUM3 SGDID:S000005824, Chr XV from 875598-877037, Verified ORF, "Protein of unknown function involved in the organization of the outer spore wall layers; has similarity to the tafazzins superfamily of acyltransferases" |
| 5308 | YOR299W | BUD7 SGDID:S000005825, Chr XV from 878433-880673, Verified ORF, "Member of the ChAPs family of proteins (Chs5p-Arf1p-binding proteins: Bch1p, Bch2p, Bud7p, Chs6p), that forms the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane" |
| 5309 | YOR301W | RAX1 SGDID:S000005827, Chr XV from 880963-882270, Verified ORF, "Protein involved in bud site selection during bipolar budding; localization requires Rax2p; has similarity to members of the insulin-related peptide superfamily" |
| 5310 | YOR302W | YOR302W SGDID:S000005828, Chr XV from 882763-882840, Verified ORF, "CPA1 uORF , Arginine attenuator peptide, regulates translation of the CPA1 mRNA" |
| 5311 | YOR303W | CPA1 SGDID:S000005829, Chr XV from 882897-884132, Verified ORF, "Small subunit of carbamoyl phosphate synthetase, which catalyzes a step in the synthesis of citrulline, an arginine precursor; translationally regulated by an attenuator peptide encoded by YOR302W within the CPA1 mRNA 5'-leader" |
| 5312 | YOR304C-A | YOR304C-A SGDID:S000005830, Chr XV from 888748-888518, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck" |
| 5313 | YOR304W | ISW2 SGDID:S000005831, Chr XV from 884512-887874, Verified ORF, "Member of the imitation-switch (ISWI) class of ATP-dependent chromatin remodeling complexes; ATPase component that, with Itc1p, forms a complex required for repression of a-specific genes, INO1, and early meiotic genes during mitotic growth" |
| 5314 | YOR305W | YOR305W SGDID:S000005832, Chr XV from 889020-889748, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO); YOR305W is not an essential gene" |
| 5315 | YOR306C | MCH5 SGDID:S000005833, Chr XV from 891430-889865, reverse complement, Verified ORF, "Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylate transport" |
| 5316 | YOR307C | SLY41 SGDID:S000005834, Chr XV from 894089-892728, reverse complement, Verified ORF, "Protein involved in ER-to-Golgi transport" |
| 5317 | YOR308C | SNU66 SGDID:S000005835, Chr XV from 896384-894621, reverse complement, Verified ORF, "Component of the U4/U6.U5 snRNP complex involved in pre-mRNA splicing via spliceosome; has homology to human SART-1 and to an S. pombe protein; snu66 null mutation confers cold-sensitivity but is not lethal at normal growth temperatures" |
| 5318 | YOR310C | NOP58 SGDID:S000005837, Chr XV from 898357-896822, reverse complement, Verified ORF, "Protein involved in pre-rRNA processing, 18S rRNA synthesis, and snoRNA synthesis; component of the small subunit processome complex, which is required for processing of pre-18S rRNA" |
| 5319 | YOR311C | DGK1 SGDID:S000005838, Chr XV from 899925-899053, reverse complement, Verified ORF, "Diacylglycerol kinase, localized to the endoplasmic reticulum (ER); overproduction induces enlargement of ER-like membrane structures and suppresses a temperature-sensitive sly1 mutation; contains a CTP transferase domain" |
| 5320 | YOR312C | RPL20B SGDID:S000005839, Chr XV from 901191-901191,900764-900247, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl20Ap and has similarity to rat L18a ribosomal protein" |
| 5321 | YOR313C | SPS4 SGDID:S000005840, Chr XV from 902871-901855, reverse complement, Verified ORF, "Protein whose expression is induced during sporulation; not required for sporulation; heterologous expression in E. coli induces the SOS response that senses DNA damage" |
| 5322 | YOR315W | SFG1 SGDID:S000005842, Chr XV from 904757-905797, Verified ORF, "Nuclear protein, putative transcription factor required for growth of superficial pseudohyphae (which do not invade the agar substrate) but not for invasive pseudohyphal growth; may act together with Phd1p; potential Cdc28p substrate" |
| 5323 | YOR316C | COT1 SGDID:S000005843, Chr XV from 907552-906233, reverse complement, Verified ORF, "Vacuolar transporter that mediates zinc transport into the vacuole; overexpression confers resistance to cobalt and rhodium" |
| 5324 | YOR316C-A | YOR316C-A SGDID:S000028584, Chr XV from 907932-907723, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 5325 | YOR317W | FAA1 SGDID:S000005844, Chr XV from 909340-911442, Verified ORF, "Long chain fatty acyl-CoA synthetase with a preference for C12:0-C16:0 fatty acids; involved in the activation of imported fatty acids; localized to both lipid particles and mitochondrial outer membrane; essential for stationary phase" |
| 5326 | YOR319W | HSH49 SGDID:S000005846, Chr XV from 912819-913460, Verified ORF, "U2-snRNP associated splicing factor with similarity to the mammalian splicing factor SAP49; proposed to function as a U2-snRNP assembly factor along with Hsh155p and binding partner Cus1p; contains two RNA recognition motifs (RRM)" |
| 5327 | YOR320C | GNT1 SGDID:S000005847, Chr XV from 915091-913616, reverse complement, Verified ORF, "N-acetylglucosaminyltransferase capable of modification of N-linked glycans in the Golgi apparatus" |
| 5328 | YOR321W | PMT3 SGDID:S000005848, Chr XV from 916027-918288, Verified ORF, "Protein O-mannosyltransferase, transfers mannose residues from dolichyl phosphate-D-mannose to protein serine/threonine residues; acts in a complex with Pmt5p, can instead interact with Pmt1p in some conditions; target for new antifungals" |
| 5329 | YOR322C | LDB19 SGDID:S000005849, Chr XV from 921059-918603, reverse complement, Verified ORF, "Protein of unknown function involved in maintenance of proper telomere length; null mutant shows a reduced affinity for the alcian blue dye suggesting a decreased net negative charge of the cell surface" |
| 5330 | YOR323C | PRO2 SGDID:S000005850, Chr XV from 922902-921532, reverse complement, Verified ORF, "Gamma-glutamyl phosphate reductase, catalyzes the second step in proline biosynthesis" |
| 5331 | YOR324C | FRT1 SGDID:S000005851, Chr XV from 925037-923229, reverse complement, Verified ORF, "Tail-anchored endoplasmic reticulum membrane protein that is a substrate of the phosphatase calcineurin, interacts with homolog Frt2p, promotes cell growth in conditions of high Na+, alkaline pH, and cell wall stress" |
| 5332 | YOR326W | MYO2 SGDID:S000005853, Chr XV from 925718-930442, Verified ORF, "One of two type V myosin motors (along with MYO4) involved in actin-based transport of cargos; required for the polarized delivery of secretory vesicles, the vacuole, late Golgi elements, peroxisomes, and the mitotic spindle" |
| 5333 | YOR327C | SNC2 SGDID:S000005854, Chr XV from 931078-930731, reverse complement, Verified ORF, "Vesicle membrane receptor protein (v-SNARE) involved in the fusion between Golgi-derived secretory vesicles with the plasma membrane; member of the synaptobrevin/VAMP family of R-type v-SNARE proteins" |
| 5334 | YOR328W | PDR10 SGDID:S000005855, Chr XV from 931800-936494, Verified ORF, "ATP-binding cassette (ABC) transporter, multidrug transporter involved in the pleiotropic drug resistance network; regulated by Pdr1p and Pdr3p" |
| 5335 | YOR329C | SCD5 SGDID:S000005856, Chr XV from 939346-936728, reverse complement, Verified ORF, "Protein required for normal cortical actin organization and endocytosis; multicopy suppressor of clathrin deficiency; acts as a targeting subunit for protein phosphatase type 1" |
| 5336 | YOR330C | MIP1 SGDID:S000005857, Chr XV from 943382-939618, reverse complement, Verified ORF, "Catalytic subunit of the mitochondrial DNA polymerase; conserved C-terminal segment is required for the maintenance of mitochondrial genome." |
| 5337 | YOR332W | VMA4 SGDID:S000005859, Chr XV from 943653-944354, Verified ORF, "Subunit E of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; required for the V1 domain to assemble onto the vacuolar membrane" |
| 5338 | YOR334W | MRS2 SGDID:S000005861, Chr XV from 944593-946005, Verified ORF, "Mitochondrial inner membrane Mg(2+) channel, required for maintenance of intramitochondrial Mg(2+) concentrations at the correct level to support splicing of group II introns" |
| 5339 | YOR335C | ALA1 SGDID:S000005862, Chr XV from 949106-946230, reverse complement, Verified ORF, "Cytoplasmic alanyl-tRNA synthetase, required for protein synthesis; point mutation (cdc64-1 allele) causes cell cycle arrest at G1; lethality of null mutation is functionally complemented by human homolog" |
| 5340 | YOR336W | KRE5 SGDID:S000005863, Chr XV from 949770-953867, Verified ORF, "Protein required for beta-1,6 glucan biosynthesis; mutations result in aberrant morphology and severe growth defects" |
| 5341 | YOR337W | TEA1 SGDID:S000005864, Chr XV from 954341-956620, Verified ORF, "Ty1 enhancer activator required for full levels of Ty enhancer-mediated transcription; C6 zinc cluster DNA-binding protein" |
| 5342 | YOR338W | YOR338W SGDID:S000005865, Chr XV from 956895-957986, Uncharacterized ORF, "Putative protein of unknown function; YOR338W transcription is regulated by Azf1p and its transcript is a specific target of the G protein effector Scp160p; identified as being required for sporulation in a high-throughput mutant screen" |
| 5343 | YOR339C | UBC11 SGDID:S000005866, Chr XV from 958829-958359, reverse complement, Verified ORF, "Ubiquitin-conjugating enzyme most similar in sequence to Xenopus ubiquitin-conjugating enzyme E2-C, but not a true functional homolog of this E2; unlike E2-C, not required for the degradation of mitotic cyclin Clb2" |
| 5344 | YOR340C | RPA43 SGDID:S000005867, Chr XV from 960179-959199, reverse complement, Verified ORF, "RNA polymerase I subunit A43" |
| 5345 | YOR341W | RPA190 SGDID:S000005868, Chr XV from 960984-965978, Verified ORF, "RNA polymerase I subunit; largest subunit of RNA polymerase I" |
| 5346 | YOR342C | YOR342C SGDID:S000005869, Chr XV from 967622-966663, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and the nucleus" |
| 5347 | YOR343W-A | YOR343W-A SGDID:S000007355, Chr XV from 970575-971891, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 5348 | YOR343W-B | YOR343W-B SGDID:S000007356, Chr XV from 970575-971868,971870-975888, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 5349 | YOR344C | TYE7 SGDID:S000005871, Chr XV from 978066-977191, reverse complement, Verified ORF, "Serine-rich protein that contains a basic-helix-loop-helix (bHLH) DNA binding motif; binds E-boxes of glycolytic genes and contributes to their activation; may function as a transcriptional activator in Ty1-mediated gene expression" |
| 5350 | YOR346W | REV1 SGDID:S000005873, Chr XV from 981825-984782, Verified ORF, "Deoxycytidyl transferase, forms a complex with the subunits of DNA polymerase zeta, Rev3p and Rev7p; involved in repair of abasic sites in damaged DNA" |
| 5351 | YOR347C | PYK2 SGDID:S000005874, Chr XV from 986459-984939, reverse complement, Verified ORF, "Pyruvate kinase that appears to be modulated by phosphorylation; PYK2 transcription is repressed by glucose, and Pyk2p may be active under low glycolytic flux" |
| 5352 | YOR348C | PUT4 SGDID:S000005875, Chr XV from 988779-986896, reverse complement, Verified ORF, "Proline permease, required for high-affinity transport of proline; also transports the toxic proline analog azetidine-2-carboxylate (AzC); PUT4 transcription is repressed in ammonia-grown cells" |
| 5353 | YOR349W | CIN1 SGDID:S000005876, Chr XV from 989786-992830, Verified ORF, "Tubulin folding factor D involved in beta-tubulin (Tub2p) folding; isolated as mutant with increased chromosome loss and sensitivity to benomyl" |
| 5354 | YOR350C | MNE1 SGDID:S000005877, Chr XV from 994852-992861, reverse complement, Verified ORF, "Mitochondrial protein similar to Lucilia illustris mitochondrial cytochrome oxidase" |
| 5355 | YOR351C | MEK1 SGDID:S000005878, Chr XV from 996508-995015, reverse complement, Verified ORF, "Meiosis-specific serine/threonine protein kinase, functions in meiotic checkpoint, promotes recombination between homologous chromosomes by suppressing double strand break repair between sister chromatids" |
| 5356 | YOR352W | YOR352W SGDID:S000005879, Chr XV from 997210-998241, Uncharacterized ORF, "Putative protein of unknown function; expression levels regulated by Arg5,6p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus" |
| 5357 | YOR353C | SOG2 SGDID:S000005880, Chr XV from 1000825-998450, reverse complement, Verified ORF, "Key component of the RAM signaling network, required for proper cell morphogenesis and cell separation after mitosis" |
| 5358 | YOR354C | MSC6 SGDID:S000005881, Chr XV from 1003222-1001144, reverse complement, Verified ORF, "Protein of unknown function; mutant is defective in directing meiotic recombination events to homologous chromatids; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 5359 | YOR355W | GDS1 SGDID:S000005882, Chr XV from 1005135-1006703, Verified ORF, "Protein of unknown function, required for growth on glycerol as a carbon source; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 5360 | YOR356W | YOR356W SGDID:S000005883, Chr XV from 1007219-1009114, Verified ORF, "Mitochondrial protein with similarity to flavoprotein-type oxidoreductases; found in a large supramolecular complex with other mitochondrial dehydrogenases" |
| 5361 | YOR357C | SNX3 SGDID:S000005884, Chr XV from 1009710-1009222, reverse complement, Verified ORF, "Sorting nexin required to maintain late-Golgi resident enzymes in their proper location by recycling molecules from the prevacuolar compartment; contains a PX domain and sequence similarity to human Snx3p" |
| 5362 | YOR358W | HAP5 SGDID:S000005885, Chr XV from 1010159-1010887, Verified ORF, "Subunit of the heme-activated, glucose-repressed Hap2/3/4/5 CCAAT-binding complex, a transcriptional activator and global regulator of respiratory gene expression; required for assembly and DNA binding activity of the complex" |
| 5363 | YOR359W | VTS1 SGDID:S000005886, Chr XV from 1011187-1012758, Verified ORF, "Post-transcriptional gene regulator, RNA-binding protein containing a SAM domain; shows genetic interactions with Vti1p, which is a v-SNARE involved in cis-Golgi membrane traffic" |
| 5364 | YOR360C | PDE2 SGDID:S000005887, Chr XV from 1014819-1013239, reverse complement, Verified ORF, "High-affinity cyclic AMP phosphodiesterase, component of the cAMP-dependent protein kinase signaling system, protects the cell from extracellular cAMP, contains readthrough motif surrounding termination codon" |
| 5365 | YOR361C | PRT1 SGDID:S000005888, Chr XV from 1017650-1015359, reverse complement, Verified ORF, "Subunit of the core complex of translation initiation factor 3(eIF3), essential for translation; part of a subcomplex (Prt1p-Rpg1p-Nip1p) that stimulates binding of mRNA and tRNA(i)Met to ribosomes" |
| 5366 | YOR362C | PRE10 SGDID:S000005889, Chr XV from 1018744-1017878, reverse complement, Verified ORF, "Alpha 7 subunit of the 20S proteasome" |
| 5367 | YOR363C | PIP2 SGDID:S000005890, Chr XV from 1023210-1020220, reverse complement, Verified ORF, "Autoregulatory oleate-specific transcriptional activator of peroxisome proliferation, contains Zn(2)-Cys(6) cluster domain, forms heterodimer with Oaf1p, binds oleate response elements (OREs), activates beta-oxidation genes" |
| 5368 | YOR365C | YOR365C SGDID:S000005892, Chr XV from 1025570-1023459, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YOR365C is not an essential protein" |
| 5369 | YOR367W | SCP1 SGDID:S000005894, Chr XV from 1026005-1026607, Verified ORF, "Component of yeast cortical actin cytoskeleton, binds and cross links actin filaments; originally identified by its homology to calponin (contains a calponin-like repeat) but the Scp1p domain structure is more similar to transgelin" |
| 5370 | YOR368W | RAD17 SGDID:S000005895, Chr XV from 1026841-1028046, Verified ORF, "Checkpoint protein, involved in the activation of the DNA damage and meiotic pachytene checkpoints; with Mec3p and Ddc1p, forms a clamp that is loaded onto partial duplex DNA; homolog of human and S. pombe Rad1 and U. maydis Rec1 proteins" |
| 5371 | YOR369C | RPS12 SGDID:S000005896, Chr XV from 1028623-1028192, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; has similarity to rat ribosomal protein S12" |
| 5372 | YOR370C | MRS6 SGDID:S000005897, Chr XV from 1030992-1029181, reverse complement, Verified ORF, "Rab escort protein, forms a complex with the Ras-like small GTPase Ypt1p that is required for the prenylation of Ypt1p by protein geranylgeranyltransferase type II (Bet2p-Bet4p)" |
| 5373 | YOR371C | GPB1 SGDID:S000005898, Chr XV from 1034180-1031487, reverse complement, Verified ORF, "Multistep regulator of cAMP-PKA signaling; inhibits PKA downstream of Gpa2p and Cyr1p, thereby increasing cAMP dependency; inhibits Ras activity through direct interactions with Ira1p/2p; regulated by G-alpha protein Gpa2p; homolog of Gpb2p" |
| 5374 | YOR372C | NDD1 SGDID:S000005899, Chr XV from 1036469-1034805, reverse complement, Verified ORF, "Transcriptional activator essential for nuclear division; localized to the nucleus; essential component of the mechanism that activates the expression of a set of late-S-phase-specific genes" |
| 5375 | YOR373W | NUD1 SGDID:S000005900, Chr XV from 1036832-1039387, Verified ORF, "Component of the spindle pole body outer plaque, required for exit from mitosis" |
| 5376 | YOR374W | ALD4 SGDID:S000005901, Chr XV from 1039838-1041397, Verified ORF, "Mitochondrial aldehyde dehydrogenase, required for growth on ethanol and conversion of acetaldehyde to acetate; phosphorylated; activity is K+ dependent; utilizes NADP+ or NAD+ equally as coenzymes; expression is glucose repressed" |
| 5377 | YOR375C | GDH1 SGDID:S000005902, Chr XV from 1043040-1041676, reverse complement, Verified ORF, "NADP(+)-dependent glutamate dehydrogenase, synthesizes glutamate from ammonia and alpha-ketoglutarate; rate of alpha-ketoglutarate utilization differs from Gdh3p; expression regulated by nitrogen and carbon sources" |
| 5378 | YOR376W-A | YOR376W-A SGDID:S000028586, Chr XV from 1045194-1045349, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 5379 | YOR377W | ATF1 SGDID:S000005904, Chr XV from 1046224-1047801, Verified ORF, "Alcohol acetyltransferase with potential roles in lipid and sterol metabolism; responsible for the major part of volatile acetate ester production during fermentation" |
| 5380 | YOR378W | YOR378W SGDID:S000005905, Chr XV from 1049509-1051056, Uncharacterized ORF, "Putative protein of unknown function; belongs to the DHA2 family of drug:H+ antiporters; YOR378W is not an essential gene" |
| 5381 | YOR380W | RDR1 SGDID:S000005907, Chr XV from 1051288-1052928, Verified ORF, "Transcriptional repressor involved in the control of multidrug resistance; negatively regulates expression of the PDR5 gene; member of the Gal4p family of zinc cluster proteins" |
| 5382 | YOR381W | FRE3 SGDID:S000005908, Chr XV from 1055543-1057678, Verified ORF, "Ferric reductase, reduces siderophore-bound iron prior to uptake by transporters; expression induced by low iron levels" |
| 5383 | YOR381W-A | YOR381W-A SGDID:S000028587, Chr XV from 1058421-1058588, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 5384 | YOR382W | FIT2 SGDID:S000005909, Chr XV from 1059529-1059990, Verified ORF, "Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall" |
| 5385 | YOR383C | FIT3 SGDID:S000005910, Chr XV from 1061053-1060439, reverse complement, Verified ORF, "Mannoprotein that is incorporated into the cell wall via a glycosylphosphatidylinositol (GPI) anchor, involved in the retention of siderophore-iron in the cell wall" |
| 5386 | YOR384W | FRE5 SGDID:S000005911, Chr XV from 1061562-1063646, Verified ORF, "Putative ferric reductase with similarity to Fre2p; expression induced by low iron levels; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 5387 | YOR385W | YOR385W SGDID:S000005912, Chr XV from 1065041-1065913, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YOR385W is not an essential gene" |
| 5388 | YOR386W | PHR1 SGDID:S000005913, Chr XV from 1066837-1068534, Verified ORF, "DNA photolyase involved in photoreactivation, repairs pyrimidine dimers in the presence of visible light; induced by DNA damage; regulated by transcriptional repressor Rph1p" |
| 5389 | YOR387C | YOR387C SGDID:S000005914, Chr XV from 1070239-1069619, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; regulated by the metal-responsive Aft1p transcription factor; highly inducible in zinc-depleted conditions; localizes to the soluble fraction" |
| 5390 | YOR388C | FDH1 SGDID:S000005915, Chr XV from 1072921-1071791, reverse complement, Verified ORF, "NAD(+)-dependent formate dehydrogenase, may protect cells from exogenous formate" |
| 5391 | YOR389W | YOR389W SGDID:S000005916, Chr XV from 1074211-1076085, Uncharacterized ORF, "Putative protein of unknown function; expression regulated by copper levels" |
| 5392 | YOR390W | YOR390W SGDID:S000005917, Chr XV from 1076782-1077909, Uncharacterized ORF, "Putative protein of unknown function" |
| 5393 | YOR391C | HSP33 SGDID:S000005918, Chr XV from 1079256-1078543, reverse complement, Verified ORF, "Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp32p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease" |
| 5394 | YOR393W | ERR1 SGDID:S000005920, Chr XV from 1080274-1081587, Verified ORF, "Protein of unknown function, has similarity to enolases" |
| 5395 | YOR394C-A | YOR394C-A SGDID:S000028718, Chr XV from 1084367-1084200, reverse complement, Uncharacterized ORF, "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 5396 | YOR394W | YOR394W SGDID:S000005921, Chr XV from 1082716-1083210, Uncharacterized ORF, "Hypothetical protein" |
| 5397 | YOR396W | YRF1-8 SGDID:S000007526, Chr XV from 1085471-1090861, Uncharacterized ORF, "One of several telomeric Y' element-encoded DNA helicases, known as Y'-Help1 (Y'-HELicase Protein 1)" |
| 5398 | YPL001W | HAT1 SGDID:S000005922, Chr XVI from 554602-555726, Verified ORF, "Catalytic subunit of the Hat1p-Hat2p histone acetyltransferase complex that uses the cofactor acetyl coenzyme A, to acetylate free nuclear and cytoplasmic histone H4; involved in telomeric silencing and DNA double-strand break repair" |
| 5399 | YPL002C | SNF8 SGDID:S000005923, Chr XVI from 554325-553624, reverse complement, Verified ORF, "Component of the ESCRT-II complex, which is involved in ubiquitin-dependent sorting of proteins into the endosome; appears to be functionally related to SNF7; involved in glucose derepression" |
| 5400 | YPL003W | ULA1 SGDID:S000005924, Chr XVI from 552017-553405, Verified ORF, "Protein that acts together with Uba3p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation" |
| 5401 | YPL004C | LSP1 SGDID:S000005925, Chr XVI from 551654-550629, reverse complement, Verified ORF, "Primary component of eisosomes, which are large immobile patch structures at the cell cortex associated with endocytosis, along with Pil1p and Sur7p; null mutants show activation of Pkc1p/Ypk1p stress resistance pathways" |
| 5402 | YPL005W | AEP3 SGDID:S000005926, Chr XVI from 548483-550303, Verified ORF, "Peripheral mitochondrial inner membrane protein, located on the matrix face of the membrane; stabilizes the bicistronic AAP1-ATP6 mRNA encoding subunits 6 and 8 of the ATP synthase complex" |
| 5403 | YPL006W | NCR1 SGDID:S000005927, Chr XVI from 544628-548140, Verified ORF, "Vacuolar membrane protein that transits through the biosynthetic vacuolar protein sorting pathway, involved in sphingolipid metabolism; glycoprotein and functional orthologue of human Niemann Pick C1 (NPC1) protein" |
| 5404 | YPL007C | TFC8 SGDID:S000005928, Chr XVI from 543845-542079, reverse complement, Verified ORF, "One of six subunits of RNA polymerase III transcription initiation factor complex (TFIIIC); part of TFIIIC TauB domain that binds BoxB promoter sites of tRNA and other genes; linker between TauB and TauA domains; human homolog is TFIIIC-90" |
| 5405 | YPL008W | CHL1 SGDID:S000005929, Chr XVI from 539382-541967, Verified ORF, "Conserved nuclear protein required to establish sister-chromatid pairing during S-phase, probable DNA helicase with similarity to human BACH1, which associates with tumor suppressor BRCA1; associates with acetyltransferase Ctf7p" |
| 5406 | YPL009C | YPL009C SGDID:S000005930, Chr XVI from 538933-535817, reverse complement, Verified ORF, "Protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL009C is not an essential gene" |
| 5407 | YPL010W | RET3 SGDID:S000005931, Chr XVI from 535015-535584, Verified ORF, "Zeta subunit of the coatomer complex (COPI), which coats Golgi-derived transport vesicles; involved in retrograde transport between Golgi and ER" |
| 5408 | YPL011C | TAF3 SGDID:S000005932, Chr XVI from 534700-533639, reverse complement, Verified ORF, "TFIID subunit (47 kDa), involved in promoter binding and RNA polymerase II transcription initiation" |
| 5409 | YPL012W | RRP12 SGDID:S000005933, Chr XVI from 529720-533406, Verified ORF, "Protein required for export of the ribosomal subunits; associates with the RNA components of the pre-ribosomes; contains HEAT-repeats" |
| 5410 | YPL013C | MRPS16 SGDID:S000005934, Chr XVI from 529347-528982, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 5411 | YPL014W | YPL014W SGDID:S000005935, Chr XVI from 527544-528689, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and to the nucleus" |
| 5412 | YPL015C | HST2 SGDID:S000005936, Chr XVI from 526880-525807, reverse complement, Verified ORF, "Cytoplasmic member of the silencing information regulator 2 (Sir2) family of NAD(+)-dependent protein deacetylases; modulates nucleolar (rDNA) and telomeric silencing; possesses NAD(+)-dependent histone deacetylase activity in vitro" |
| 5413 | YPL016W | SWI1 SGDID:S000005937, Chr XVI from 521011-524955, Verified ORF, "Subunit of the SWI/SNF chromatin remodeling complex, which regulates transcription by remodeling chromosomes; required for transcription of many genes, including ADH1, ADH2, GAL1, HO, INO1 and SUC2; can become prion [SWI+]" |
| 5414 | YPL017C | IRC15 SGDID:S000005938, Chr XVI from 520231-518732, reverse complement, Verified ORF, "Putative S-adenosylmethionine-dependent methyltransferase of the seven beta-strand family, required for accurate meiotic chromosome segregation; null mutant displays increased levels of spontaneous Rad52 foci" |
| 5415 | YPL018W | CTF19 SGDID:S000005939, Chr XVI from 517649-518758, Verified ORF, "Outer kinetochore protein, required for accurate mitotic chromosome segregation; component of the kinetochore sub-complex COMA (Ctf19p, Okp1p, Mcm21p, Ame1p) that functions as a platform for kinetochore assembly" |
| 5416 | YPL019C | VTC3 SGDID:S000005940, Chr XVI from 517016-514509, reverse complement, Verified ORF, "Vacuolar membrane protein involved in vacuolar polyphosphate accumulation; functions as a regulator of vacuolar H+-ATPase activity and vacuolar transporter chaperones; involved in non-autophagic vacuolar fusion" |
| 5417 | YPL020C | ULP1 SGDID:S000005941, Chr XVI from 514176-512311, reverse complement, Verified ORF, "Ubl (ubiquitin-like protein)-specific protease that cleaves Smt3p protein conjugates; specifically required for cell cycle progression; associates with nucleoporins and may interact with septin rings during telophase" |
| 5418 | YPL021W | ECM23 SGDID:S000005942, Chr XVI from 511099-511662, Verified ORF, "Non-essential protein of unconfirmed function; affects pre-rRNA processing, may act as a negative regulator of the transcription of genes involved in pseudohyphal growth; homologous to Srd1p" |
| 5419 | YPL022W | RAD1 SGDID:S000005943, Chr XVI from 506695-509997, Verified ORF, "Single-stranded DNA endonuclease (with Rad10p), cleaves single-stranded DNA during nucleotide excision repair and double-strand break repair; subunit of Nucleotide Excision Repair Factor 1 (NEF1); homolog of human XPF protein" |
| 5420 | YPL023C | MET12 SGDID:S000005944, Chr XVI from 506310-504337, reverse complement, Verified ORF, "Isozyme of methylenetetrahydrofolate reductase, catalyzes the reduction of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate in the methionine biosynthesis pathway" |
| 5421 | YPL024W | RMI1 SGDID:S000005945, Chr XVI from 503515-504240, Verified ORF, "Involved in response to DNA damage; null mutants have increased rates of recombination and delayed S phase; interacts physically and genetically with Sgs1p (RecQ family member) and Top3p (topoisomerase III)" |
| 5422 | YPL026C | SKS1 SGDID:S000005947, Chr XVI from 502181-500673, reverse complement, Verified ORF, "Putative serine/threonine protein kinase; involved in the adaptation to low concentrations of glucose independent of the SNF3 regulated pathway" |
| 5423 | YPL027W | SMA1 SGDID:S000005948, Chr XVI from 499663-500400, Verified ORF, "Protein of unknown function involved in the assembly of the prospore membrane during sporulation" |
| 5424 | YPL028W | ERG10 SGDID:S000005949, Chr XVI from 498094-499290, Verified ORF, "Acetyl-CoA C-acetyltransferase (acetoacetyl-CoA thiolase), cytosolic enzyme that transfers an acetyl group from one acetyl-CoA molecule to another, forming acetoacetyl-CoA; involved in the first step in mevalonate biosynthesis" |
| 5425 | YPL029W | SUV3 SGDID:S000005950, Chr XVI from 495504-497717, Verified ORF, "ATP-dependent RNA helicase, component of the mitochondrial degradosome along with the RNase Dss1p; the degradosome associates with the ribosome and mediates turnover of aberrant or unprocessed RNAs" |
| 5426 | YPL030W | TRM44 SGDID:S000005951, Chr XVI from 493541-495244, Verified ORF, "tRNA(Ser) Um(44) 2'-O-methyltransferase; involved in maintaining levels of the tRNA-Ser species tS(CGA) and tS(UGA); conserved among metazoans and fungi but there does not appear to be a homolog in plants; TRM44 is a non-essential gene" |
| 5427 | YPL031C | PHO85 SGDID:S000005952, Chr XVI from 493035-493019,492916-492016, reverse complement, Verified ORF, "Cyclin-dependent kinase, with ten cyclin partners; involved in regulating the cellular response to nutrient levels and environmental conditions and progression through the cell cycle" |
| 5428 | YPL032C | SVL3 SGDID:S000005953, Chr XVI from 491362-488885, reverse complement, Verified ORF, "Protein of unknown function, mutant phenotype suggests a potential role in vacuolar function; green fluorescent protein (GFP)-fusion protein localizes to the cell periphery, cytoplasm, bud, and bud neck" |
| 5429 | YPL033C | YPL033C SGDID:S000005954, Chr XVI from 488205-487360, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; may be involved in DNA metabolism; expression is induced by Kar4p" |
| 5430 | YPL034W | YPL034W SGDID:S000005955, Chr XVI from 486710-487207, Uncharacterized ORF, "Putative protein of unknown function; YPL034W is not essential gene" |
| 5431 | YPL036W | PMA2 SGDID:S000005957, Chr XVI from 482841-485684, Verified ORF, "Plasma membrane H+-ATPase, isoform of Pma1p, involved in pumping protons out of the cell; regulator of cytoplasmic pH and plasma membrane potential" |
| 5432 | YPL037C | EGD1 SGDID:S000005958, Chr XVI from 481898-481425, reverse complement, Verified ORF, "Subunit beta1 of the nascent polypeptide-associated complex (NAC) involved in protein targeting, associated with cytoplasmic ribosomes; enhances DNA binding of the Gal4p activator; homolog of human BTF3b" |
| 5433 | YPL038W | MET31 SGDID:S000005959, Chr XVI from 480532-481065, Verified ORF, "Zinc-finger DNA-binding protein, involved in transcriptional regulation of the methionine biosynthetic genes, similar to Met32p" |
| 5434 | YPL038W-A | YPL038W-A SGDID:S000028588, Chr XVI from 480179-480370, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 5435 | YPL039W | YPL039W SGDID:S000005960, Chr XVI from 479222-480172, Uncharacterized ORF, "Putative protein of unknown function; YPL039W is not an essential gene" |
| 5436 | YPL040C | ISM1 SGDID:S000005961, Chr XVI from 478998-475990, reverse complement, Verified ORF, "Mitochondrial isoleucyl-tRNA synthetase, null mutant is deficient in respiratory growth" |
| 5437 | YPL041C | YPL041C SGDID:S000005962, Chr XVI from 475738-475115, reverse complement, Uncharacterized ORF, "Protein of unknown function involved in maintenance of proper telomere length" |
| 5438 | YPL042C | SSN3 SGDID:S000005963, Chr XVI from 474704-473037, reverse complement, Verified ORF, "Cyclin-dependent protein kinase, component of RNA polymerase II holoenzyme; involved in phosphorylation of the RNA polymerase II C-terminal domain; involved in glucose repression" |
| 5439 | YPL043W | NOP4 SGDID:S000005964, Chr XVI from 469936-471993, Verified ORF, "Nucleolar protein, essential for processing and maturation of 27S pre-rRNA and large ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; contains four RNA recognition motifs (RRMs)" |
| 5440 | YPL045W | VPS16 SGDID:S000005966, Chr XVI from 467257-469653, Verified ORF, "Subunit of the vacuole fusion and protein sorting HOPS complex and the CORVET tethering complex; part of the Class C Vps complex essential for membrane docking and fusion at Golgi-to-endosome and endosome-to-vacuole protein transport stages" |
| 5441 | YPL046C | ELC1 SGDID:S000005967, Chr XVI from 466940-466641, reverse complement, Verified ORF, "Elongin C, forms heterodimer with Ela1p that participates in transcription elongation; required for ubiquitin-dependent degradation of the RNA Polymerase II subunit RPO21; expression dramatically upregulated during sporulation" |
| 5442 | YPL047W | SGF11 SGDID:S000005968, Chr XVI from 465959-466258, Verified ORF, "Integral subunit of SAGA histone acetyltransferase complex, regulates transcription of a subset of SAGA-regulated genes, required for the Ubp8p association with SAGA and for H2B deubiquitylation" |
| 5443 | YPL048W | CAM1 SGDID:S000005969, Chr XVI from 464398-465645, Verified ORF, "Nuclear protein required for transcription of MXR1; binds the MXR1 promoter in the presence of other nuclear factors; binds calcium and phospholipids; has similarity to translational cofactor EF-1 gamma" |
| 5444 | YPL049C | DIG1 SGDID:S000005970, Chr XVI from 463836-462478, reverse complement, Verified ORF, "Regulatory protein of unknown function, constitutively-expressed, involved in the regulation of mating-specific genes and the invasive growth pathway, required for MAP-kinase imposed repression, inhibits pheromone-responsive transcription" |
| 5445 | YPL050C | MNN9 SGDID:S000005971, Chr XVI from 461963-460776, reverse complement, Verified ORF, "Subunit of Golgi mannosyltransferase complex also containing Anp1p, Mnn10p, Mnn11p, and Hoc1p that mediates elongation of the polysaccharide mannan backbone; forms a separate complex with Van1p that is also involved in backbone elongation" |
| 5446 | YPL051W | ARL3 SGDID:S000005972, Chr XVI from 459960-460556, Verified ORF, "GTPase of the Ras superfamily required to recruit Arl1p to the Golgi; similar to ADP-ribosylation factor" |
| 5447 | YPL052W | OAZ1 SGDID:S000005973, Chr XVI from 458796-459002,459004-459675, Verified ORF, "Regulator of ornithine decarboxylase (Spe1p), antizyme that binds to Spe1p to regulate ubiquitin-independent degradation; ribosomal frameshifting during synthesis of Oaz1p and its ubiquitin-mediated degradation are both polyamine-regulated" |
| 5448 | YPL053C | KTR6 SGDID:S000005974, Chr XVI from 458455-457115, reverse complement, Verified ORF, "Probable mannosylphosphate transferase involved in the synthesis of core oligosaccharides in protein glycosylation pathway; member of the KRE2/MNT1 mannosyltransferase family" |
| 5449 | YPL054W | LEE1 SGDID:S000005975, Chr XVI from 455756-456661, Verified ORF, "Zinc-finger protein of unknown function" |
| 5450 | YPL055C | LGE1 SGDID:S000005976, Chr XVI from 454987-453989, reverse complement, Verified ORF, "Protein of unknown function; null mutant forms abnormally large cells, and homozygous diploid null mutant displays delayed premeiotic DNA synthesis and reduced efficiency of meiotic nuclear division" |
| 5451 | YPL056C | YPL056C SGDID:S000005977, Chr XVI from 453732-453427, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; deletion mutant is fluconazole resistant" |
| 5452 | YPL057C | SUR1 SGDID:S000005978, Chr XVI from 453054-451906, reverse complement, Verified ORF, "Probable catalytic subunit of a mannosylinositol phosphorylceramide (MIPC) synthase, forms a complex with probable regulatory subunit Csg2p; function in sphingolipid biosynthesis is overlapping with that of Csh1p" |
| 5453 | YPL058C | PDR12 SGDID:S000005979, Chr XVI from 450374-445839, reverse complement, Verified ORF, "Plasma membrane ATP-binding cassette (ABC) transporter, weak-acid-inducible multidrug transporter required for weak organic acid resistance; induced by sorbate and benzoate and regulated by War1p; mutants exhibit sorbate hypersensitivity" |
| 5454 | YPL059W | GRX5 SGDID:S000005980, Chr XVI from 444576-445028, Verified ORF, "Hydroperoxide and superoxide-radical responsive glutathione-dependent oxidoreductase; mitochondrial matrix protein involved in the synthesis/assembly of iron-sulfur centers; monothiol glutaredoxin subfamily member along with Grx3p and Grx4p" |
| 5455 | YPL060W | LPE10 SGDID:S000005981, Chr XVI from 434520-435761, Verified ORF, "Mitochondrial inner membrane magnesium transporter, involved in maintenance of magnesium concentrations inside mitochondria; indirectly affects splicing of group II introns; functionally and structurally related to Mrs2p" |
| 5456 | YPL061W | ALD6 SGDID:S000005982, Chr XVI from 432585-434087, Verified ORF, "Cytosolic aldehyde dehydrogenase, activated by Mg2+ and utilizes NADP+ as the preferred coenzyme; required for conversion of acetaldehyde to acetate; constitutively expressed; locates to the mitochondrial outer surface upon oxidative stress" |
| 5457 | YPL063W | TIM50 SGDID:S000005984, Chr XVI from 429936-431366, Verified ORF, "Constituent of the mitochondrial inner membrane presequence translocase (TIM23 complex); may promote binding of incoming precursor proteins to the intermembrane space domain of Tom22p during translocation" |
| 5458 | YPL064C | CWC27 SGDID:S000005985, Chr XVI from 429613-428708, reverse complement, Verified ORF, "Component of a complex containing Cef1p, putatively involved in pre-mRNA splicing; has similarity to S. pombe Cwf27p" |
| 5459 | YPL065W | VPS28 SGDID:S000005986, Chr XVI from 427924-428652, Verified ORF, "Component of the ESCRT-I complex (Stp22p, Srn2p, Vps28p, and Mvb12p), which is involved in ubiquitin-dependent sorting of proteins into the endosome; conserved C-terminal domain interacts with ESCRT-III subunit Vps20p" |
| 5460 | YPL066W | YPL066W SGDID:S000005987, Chr XVI from 426230-427669, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the bud neck and cytoplasm; null mutant is viable and exhibits growth defect on a non-fermentable (respiratory) carbon source" |
| 5461 | YPL067C | YPL067C SGDID:S000005988, Chr XVI from 425844-425248, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL067C is not an essential gene" |
| 5462 | YPL068C | YPL068C SGDID:S000005989, Chr XVI from 425093-424212, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleus and is induced in response to the DNA-damaging agent MMS" |
| 5463 | YPL069C | BTS1 SGDID:S000005990, Chr XVI from 423889-422882, reverse complement, Verified ORF, "Geranylgeranyl diphosphate synthase, increases the intracellular pool of geranylgeranyl diphosphate, suppressor of bet2 mutation that causes defective geranylgeranylation of small GTP-binding proteins that mediate vesicular traffic" |
| 5464 | YPL070W | MUK1 SGDID:S000005991, Chr XVI from 420945-422783, Verified ORF, "Cytoplasmic protein of unknown function; computational analysis of large-scale protein-protein interaction data suggests a possible role in transcriptional regulation" |
| 5465 | YPL071C | YPL071C SGDID:S000005992, Chr XVI from 420515-420045, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus" |
| 5466 | YPL072W | UBP16 SGDID:S000005993, Chr XVI from 418509-420008, Verified ORF, "Deubiquitinating enzyme anchored to the outer mitochondrial membrane, probably not important for general mitochondrial functioning, but may perform a more specialized function at mitochondria" |
| 5467 | YPL074W | YTA6 SGDID:S000005995, Chr XVI from 415760-418024, Verified ORF, "Putative ATPase of the CDC48/PAS1/SEC18 (AAA) family, localized to the cortex of mother cells but not to daughter cells" |
| 5468 | YPL075W | GCR1 SGDID:S000005996, Chr XVI from 412251-412258,413010-415359, Verified ORF, "Transcriptional activator of genes involved in glycolysis; DNA-binding protein that interacts and functions with the transcriptional activator Gcr2p" |
| 5469 | YPL076W | GPI2 SGDID:S000005997, Chr XVI from 410440-411282, Verified ORF, "Protein involved in the synthesis of N-acetylglucosaminyl phosphatidylinositol (GlcNAc-PI), the first intermediate in the synthesis of glycosylphosphatidylinositol (GPI) anchors; homologous to the human PIG-C protein" |
| 5470 | YPL077C | YPL077C SGDID:S000005998, Chr XVI from 410087-409365, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; regulates PIS1 expression; mutant displays spore wall assembly defect in ether sensitivity screen; YPL077C is not an essential gene" |
| 5471 | YPL078C | ATP4 SGDID:S000005999, Chr XVI from 408741-408007, reverse complement, Verified ORF, "Subunit b of the stator stalk of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" |
| 5472 | YPL079W | RPL21B SGDID:S000006000, Chr XVI from 406633-406643,407065-407536, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl21Ap and has similarity to rat L21 ribosomal protein" |
| 5473 | YPL081W | RPS9A SGDID:S000006002, Chr XVI from 404947-404953,405455-406041, Verified ORF, "Protein component of the small (40S) ribosomal subunit; nearly identical to Rps9Bp and has similarity to E. coli S4 and rat S9 ribosomal proteins" |
| 5474 | YPL082C | MOT1 SGDID:S000006003, Chr XVI from 404080-398477, reverse complement, Verified ORF, "Essential abundant protein involved in regulation of transcription, removes Spt15p (TBP) from DNA via its C-terminal ATPase activity, forms a complex with TBP that binds TATA DNA with high affinity but with altered specificity" |
| 5475 | YPL083C | SEN54 SGDID:S000006004, Chr XVI from 398102-396699, reverse complement, Verified ORF, "Subunit of the tRNA splicing endonuclease, which is composed of Sen2p, Sen15p, Sen34p, and Sen54p" |
| 5476 | YPL084W | BRO1 SGDID:S000006005, Chr XVI from 394035-396569, Verified ORF, "Cytoplasmic class E vacuolar protein sorting (VPS) factor that coordinates deubiquitination in the multivesicular body (MVB) pathway by recruiting Doa4p to endosomes" |
| 5477 | YPL085W | SEC16 SGDID:S000006006, Chr XVI from 387064-393651, Verified ORF, "COPII vesicle coat protein required for ER transport vesicle budding and autophagosome formation; Sec16p is bound to the periphery of ER membranes and may act to stabilize initial COPII complexes; interacts with Sec23p, Sec24p and Sec31p" |
| 5478 | YPL086C | ELP3 SGDID:S000006007, Chr XVI from 386443-384770, reverse complement, Verified ORF, "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; exhibits histone acetyltransferase activity that is directed to histones H3 and H4; disruption confers resistance to K. lactis zymotoxin" |
| 5479 | YPL087W | YDC1 SGDID:S000006008, Chr XVI from 383452-384405, Verified ORF, "Alkaline dihydroceramidase, involved in sphingolipid metabolism; preferentially hydrolyzes dihydroceramide to a free fatty acid and dihydrosphingosine; has a minor reverse activity" |
| 5480 | YPL088W | YPL088W SGDID:S000006009, Chr XVI from 381962-382990, Uncharacterized ORF, "Putative aryl alcohol dehydrogenase; transcription is activated by paralogous transcription factors Yrm1p and Yrr1p along with genes involved in multidrug resistance" |
| 5481 | YPL089C | RLM1 SGDID:S000006010, Chr XVI from 381147-379117, reverse complement, Verified ORF, "MADS-box transcription factor, component of the protein kinase C-mediated MAP kinase pathway involved in the maintenance of cell integrity; phosphorylated and activated by the MAP-kinase Slt2p" |
| 5482 | YPL090C | RPS6A SGDID:S000006011, Chr XVI from 378392-378387,377992-377288, reverse complement, Verified ORF, "Protein component of the small (40S) ribosomal subunit; identical to Rps6Bp and has similarity to rat S6 ribosomal protein" |
| 5483 | YPL091W | GLR1 SGDID:S000006012, Chr XVI from 375499-376950, Verified ORF, "Cytosolic and mitochondrial glutathione oxidoreductase, converts oxidized glutathione to reduced glutathione" |
| 5484 | YPL092W | SSU1 SGDID:S000006013, Chr XVI from 373790-375166, Verified ORF, "Plasma membrane sulfite pump involved in sulfite metabolism and required for efficient sulfite efflux; major facilitator superfamily protein" |
| 5485 | YPL093W | NOG1 SGDID:S000006014, Chr XVI from 370975-372918, Verified ORF, "Putative GTPase that associates with free 60S ribosomal subunits in the nucleolus and is required for 60S ribosomal subunit biogenesis; constituent of 66S pre-ribosomal particles; member of the ODN family of nucleolar G-proteins" |
| 5486 | YPL094C | SEC62 SGDID:S000006015, Chr XVI from 370660-369836, reverse complement, Verified ORF, "Essential subunit of Sec63 complex (Sec63p, Sec62p, Sec66p and Sec72p); with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER" |
| 5487 | YPL095C | EEB1 SGDID:S000006016, Chr XVI from 369438-368068, reverse complement, Verified ORF, "Acyl-coenzymeA:ethanol O-acyltransferase responsible for the major part of medium-chain fatty acid ethyl ester biosynthesis during fermentation; possesses short-chain esterase activity; may be involved in lipid metabolism and detoxification" |
| 5488 | YPL096C-A | ERI1 SGDID:S000028423, Chr XVI from 366732-366526, reverse complement, Verified ORF, "Endoplasmic reticulum membrane protein that binds to and inhibits GTP-bound Ras2p at the ER; component of the GPI-GnT complex which catalyzes the first step in GPI-anchor biosynthesis; probable homolog of mammalian PIG-Y protein" |
| 5489 | YPL096W | PNG1 SGDID:S000006017, Chr XVI from 366924-368015, Verified ORF, "Conserved peptide N-glycanase required for deglycosylation of misfolded glycoproteins during proteasome-dependent degradation, localizes to the cytoplasm and nucleus, interacts with the DNA repair protein Rad23p" |
| 5490 | YPL097W | MSY1 SGDID:S000006018, Chr XVI from 364949-366427, Verified ORF, "Mitochondrial tyrosyl-tRNA synthetase" |
| 5491 | YPL098C | MGR2 SGDID:S000006019, Chr XVI from 364724-364383, reverse complement, Verified ORF, "Protein required for growth of cells lacking the mitochondrial genome" |
| 5492 | YPL099C | YPL099C SGDID:S000006020, Chr XVI from 364065-363517, reverse complement, Uncharacterized ORF, "Protein of unknown function;non-tagged protein detected in purified mitochondria in high-throughput studies; null mutant displays increased frequency of mitochondrial genome loss and severe growth defect in minimal glycerol media" |
| 5493 | YPL100W | ATG21 SGDID:S000006021, Chr XVI from 361869-363359, Verified ORF, "Phosphoinositide binding protein required for vesicle formation in the cytoplasm-to-vacuole targeting (Cvt) pathway; binds both phosphatidylinositol (3,5)-bisphosphate and phosphatidylinositol 3-phosphate; WD-40 repeat protein" |
| 5494 | YPL101W | ELP4 SGDID:S000006022, Chr XVI from 360206-361576, Verified ORF, "Subunit of Elongator complex, which is required for modification of wobble nucleosides in tRNA; required for Elongator structural integrity" |
| 5495 | YPL103C | FMP30 SGDID:S000006024, Chr XVI from 359403-357997, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 5496 | YPL104W | MSD1 SGDID:S000006025, Chr XVI from 355697-357673, Verified ORF, "Mitochondrial aspartyl-tRNA synthetase, required for acylation of aspartyl-tRNA; yeast and bacterial aspartyl-, asparaginyl-, and lysyl-tRNA synthetases contain regions with high sequence similarity, suggesting a common ancestral gene" |
| 5497 | YPL105C | SYH1 SGDID:S000006026, Chr XVI from 355409-352860, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 5498 | YPL106C | SSE1 SGDID:S000006027, Chr XVI from 352272-350191, reverse complement, Verified ORF, "ATPase that is a component of the heat shock protein Hsp90 chaperone complex; binds unfolded proteins; member of the heat shock protein 70 (HSP70) family; localized to the cytoplasm" |
| 5499 | YPL107W | YPL107W SGDID:S000006028, Chr XVI from 349116-349862, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to mitochondria; YPL107W is not an essential gene" |
| 5500 | YPL108W | YPL108W SGDID:S000006029, Chr XVI from 348443-348949, Uncharacterized ORF, "Cytoplasmic protein of unknown function; non-essential gene that is induced in a GDH1 deleted strain with altered redox metabolism; GFP-fusion protein is induced in response to the DNA-damaging agent MMS" |
| 5501 | YPL109C | YPL109C SGDID:S000006030, Chr XVI from 347388-345596,345443-345263, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 5502 | YPL110C | GDE1 SGDID:S000006031, Chr XVI from 344738-341067, reverse complement, Verified ORF, "Glycerophosphocholine (GroPCho) phosphodiesterase; hydrolyzes GroPCho to choline and glycerolphosphate, for use as a phosphate source and as a precursor for phosphocholine synthesis; may interact with ribosomes" |
| 5503 | YPL111W | CAR1 SGDID:S000006032, Chr XVI from 339943-340944, Verified ORF, "Arginase, responsible for arginine degradation, expression responds to both induction by arginine and nitrogen catabolite repression; disruption enhances freeze tolerance" |
| 5504 | YPL112C | PEX25 SGDID:S000006033, Chr XVI from 338619-337435, reverse complement, Verified ORF, "Peripheral peroxisomal membrane peroxin required for the regulation of peroxisome size and maintenance, recruits GTPase Rho1p to peroxisomes, induced by oleate, interacts with homologous protein Pex27p" |
| 5505 | YPL113C | YPL113C SGDID:S000006034, Chr XVI from 337142-335952, reverse complement, Uncharacterized ORF, "Glyoxylate reductase; acts on glyoxylate and hydroxypyruvate substrates; YPL113C is not an essential gene" |
| 5506 | YPL115C | BEM3 SGDID:S000006036, Chr XVI from 335485-332099, reverse complement, Verified ORF, "Rho GTPase activating protein (RhoGAP) involved in control of the cytoskeleton organization; targets the essential Rho-GTPase Cdc42p, which controls establishment and maintenance of cell polarity, including bud-site assembly" |
| 5507 | YPL116W | HOS3 SGDID:S000006037, Chr XVI from 329605-331698, Verified ORF, "Trichostatin A-insensitive homodimeric histone deacetylase (HDAC) with specificity in vitro for histones H3, H4, H2A, and H2B; similar to Hda1p, Rpd3p, Hos1p, and Hos2p; deletion results in increased histone acetylation at rDNA repeats" |
| 5508 | YPL117C | IDI1 SGDID:S000006038, Chr XVI from 328729-327863, reverse complement, Verified ORF, "Isopentenyl diphosphate:dimethylallyl diphosphate isomerase (IPP isomerase), catalyzes an essential activation step in the isoprenoid biosynthetic pathway; required for viability" |
| 5509 | YPL118W | MRP51 SGDID:S000006039, Chr XVI from 326627-327661, Verified ORF, "Mitochondrial ribosomal protein of the small subunit; MRP51 exhibits genetic interactions with mutations in the COX2 and COX3 mRNA 5'-untranslated leader sequences" |
| 5510 | YPL119C | DBP1 SGDID:S000006040, Chr XVI from 326263-324410, reverse complement, Verified ORF, "Putative ATP-dependent RNA helicase of the DEAD-box protein family; mutants show reduced stability of the 40S ribosomal subunit scanning through 5' untranslated regions of mRNAs" |
| 5511 | YPL119C-A | YPL119C-A SGDID:S000028859, Chr XVI from 324286-324023, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; identified by expression profiling and mass spectrometry" |
| 5512 | YPL120W | VPS30 SGDID:S000006041, Chr XVI from 322070-323743, Verified ORF, "Subunit of phosphatidylinositol (PtdIns) 3-kinase complexes I and II; Complex I is essential in autophagy and Complex II is required for vacuolar protein sorting; ortholog of the higher eukaryotic gene Beclin 1" |
| 5513 | YPL121C | MEI5 SGDID:S000006042, Chr XVI from 321629-320961, reverse complement, Verified ORF, "Meiosis specific protein involved in DMC1-dependent meiotic recombination, forms heterodimer with Sae3p; proposed to be an assembly factor for Dmc1p" |
| 5514 | YPL122C | TFB2 SGDID:S000006043, Chr XVI from 320766-319225, reverse complement, Verified ORF, "Subunit of TFIIH and nucleotide excision repair factor 3 complexes, involved in transcription initiation, required for nucleotide excision repair, similar to 52 kDa subunit of human TFIIH" |
| 5515 | YPL123C | RNY1 SGDID:S000006044, Chr XVI from 318944-317640, reverse complement, Verified ORF, "RNAse; member of the T(2) family of endoribonucleases" |
| 5516 | YPL124W | SPC29 SGDID:S000006045, Chr XVI from 316754-317515, Verified ORF, "Inner plaque spindle pole body (SPB) component, links the central plaque component Spc42p to the inner plaque component Spc110p; required for SPB duplication" |
| 5517 | YPL125W | KAP120 SGDID:S000006046, Chr XVI from 313387-316485, Verified ORF, "Karyopherin with a role in the assembly or export of 60S ribosomal subunits" |
| 5518 | YPL126W | NAN1 SGDID:S000006047, Chr XVI from 310209-312899, Verified ORF, "U3 snoRNP protein, component of the small (ribosomal) subunit (SSU) processosome containing U3 snoRNA; required for the biogenesis of18S rRNA" |
| 5519 | YPL127C | HHO1 SGDID:S000006048, Chr XVI from 309603-308827, reverse complement, Verified ORF, "Histone H1, a linker histone required for nucleosome packaging at restricted sites; suppresses DNA repair involving homologous recombination; not required for telomeric silencing, basal transcriptional repression, or efficient sporulation" |
| 5520 | YPL128C | TBF1 SGDID:S000006049, Chr XVI from 308220-306532, reverse complement, Verified ORF, "Telobox-containing general regulatory factor; binds to TTAGGG repeats within subtelomeric anti-silencing regions (STARs) and possibly throughout the genome and mediates their insulating capacity by blocking silent chromatin propagation" |
| 5521 | YPL129W | TAF14 SGDID:S000006050, Chr XVI from 305297-305305,305411-306136, Verified ORF, "Subunit of TFIID, TFIIF, INO80, SWI/SNF, and NuA3 complexes, involved in RNA polymerase II transcription initiation and in chromatin modification; contains a YEATS domain" |
| 5522 | YPL130W | SPO19 SGDID:S000006051, Chr XVI from 304386-305057, Verified ORF, "Meiosis-specific protein of unknown function, involved in completion of nuclear divisions; identified as a weak high-copy suppressor of the spo1-1 ts mutation; putative GPI-dependent cell-wall protein" |
| 5523 | YPL131W | RPL5 SGDID:S000006052, Chr XVI from 303120-304013, Verified ORF, "Protein component of the large (60S) ribosomal subunit with similarity to E. coli L18 and rat L5 ribosomal proteins; binds 5S rRNA and is required for 60S subunit assembly" |
| 5524 | YPL132W | COX11 SGDID:S000006053, Chr XVI from 301715-302617, Verified ORF, "Mitochondrial inner membrane protein required for delivery of copper to the Cox1p subunit of cytochrome c oxidase; association with mitochondrial ribosomes suggests that copper delivery may occur during translation of Cox1p" |
| 5525 | YPL133C | RDS2 SGDID:S000006054, Chr XVI from 301227-299887, reverse complement, Verified ORF, "Zinc cluster transcriptional activator involved in conferring resistance to ketoconazole" |
| 5526 | YPL134C | ODC1 SGDID:S000006055, Chr XVI from 299502-298570, reverse complement, Verified ORF, "Mitochondrial inner membrane transporter, exports 2-oxoadipate and 2-oxoglutarate from the mitochondrial matrix to the cytosol for lysine and glutamate biosynthesis and lysine catabolism; suppresses, in multicopy, an fmc1 null mutation" |
| 5527 | YPL135W | ISU1 SGDID:S000006056, Chr XVI from 297552-298049, Verified ORF, "Conserved protein of the mitochondrial matrix, performs a scaffolding function during assembly of iron-sulfur clusters, interacts physically and functionally with yeast frataxin (Yfh1p); isu1 isu2 double mutant is inviable" |
| 5528 | YPL137C | GIP3 SGDID:S000006058, Chr XVI from 296646-292816, reverse complement, Verified ORF, "Glc7-interacting protein whose overexpression relocalizes Glc7p from the nucleus and prevents chromosome segregation; may interact with ribosomes, based on co-purification experiments" |
| 5529 | YPL138C | SPP1 SGDID:S000006059, Chr XVI from 292426-291365, reverse complement, Verified ORF, "Subunit of COMPASS (Set1C), a complex which methylates histone H3 on lysine 4 and is required in telomeric transcriptional silencing; PHD finger domain protein similar to human CGBP, an unmethylated CpG binding protein" |
| 5530 | YPL139C | UME1 SGDID:S000006060, Chr XVI from 291050-289668, reverse complement, Verified ORF, "Negative regulator of meiosis, required for repression of a subset of meiotic genes during vegetative growth, binding of histone deacetylase Rpd3p required for activity, contains a NEE box and a WD repeat motif; homologous with Wtm1p, Wtm2p" |
| 5531 | YPL140C | MKK2 SGDID:S000006061, Chr XVI from 289033-287513, reverse complement, Verified ORF, "Mitogen-activated kinase kinase involved in protein kinase C signaling pathway that controls cell integrity; upon activation by Bck1p phosphorylates downstream target, Slt2p; functionally redundant with Mkk1p" |
| 5532 | YPL141C | YPL141C SGDID:S000006062, Chr XVI from 286060-283463, reverse complement, Uncharacterized ORF, "Putative protein kinase; similar to Kin4p; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL141C is not an essential gene" |
| 5533 | YPL143W | RPL33A SGDID:S000006064, Chr XVI from 282121-282139,282665-282969, Verified ORF, "N-terminally acetylated ribosomal protein L37 of the large (60S) ribosomal subunit, nearly identical to Rpl33Bp and has similarity to rat L35a; rpl33a null mutant exhibits slow growth while rpl33a rpl33b double null mutant is inviable" |
| 5534 | YPL144W | POC4 SGDID:S000006065, Chr XVI from 280479-280925, Verified ORF, "Component of a heterodimeric Poc4p-Irc25p chaperone involved in assembly of alpha subunits into the 20S proteasome; may regulate formation of proteasome isoforms with alternative subunits under different conditions" |
| 5535 | YPL145C | KES1 SGDID:S000006066, Chr XVI from 279698-278394, reverse complement, Verified ORF, "Member of the oxysterol binding protein family, which includes seven yeast homologs; involved in negative regulation of Sec14p-dependent Golgi complex secretory functions, peripheral membrane protein that localizes to the Golgi complex" |
| 5536 | YPL146C | NOP53 SGDID:S000006067, Chr XVI from 277528-276161, reverse complement, Verified ORF, "Nucleolar protein; involved in biogenesis of the 60S subunit of the ribosome; interacts with rRNA processing factors Cbf5p and Nop2p; null mutant is viable but growth is severely impaired" |
| 5537 | YPL147W | PXA1 SGDID:S000006068, Chr XVI from 273254-275866, Verified ORF, "Subunit of a heterodimeric peroxisomal ATP-binding cassette transporter complex (Pxa1p-Pxa2p), required for import of long-chain fatty acids into peroxisomes; similarity to human adrenoleukodystrophy transporter and ALD-related proteins" |
| 5538 | YPL148C | PPT2 SGDID:S000006069, Chr XVI from 272814-272293, reverse complement, Verified ORF, "Phosphopantetheine:protein transferase (PPTase), activates mitochondrial acyl carrier protein (Acp1p) by phosphopantetheinylation" |
| 5539 | YPL149W | ATG5 SGDID:S000006070, Chr XVI from 271309-272193, Verified ORF, "Conserved protein involved in autophagy and the Cvt pathway; undergoes conjugation with Atg12p to form a complex involved in Atg8p lipidation; conjugated Atg12p also forms a complex with Atg16p that is essential for autophagosome formation" |
| 5540 | YPL150W | YPL150W SGDID:S000006071, Chr XVI from 268187-270892, Uncharacterized ORF, "Putative protein kinase of unknown cellular role" |
| 5541 | YPL151C | PRP46 SGDID:S000006072, Chr XVI from 267534-266179, reverse complement, Verified ORF, "Splicing factor that is found in the Cef1p subcomplex of the spliceosome" |
| 5542 | YPL152W | RRD2 SGDID:S000006073, Chr XVI from 265027-266103, Verified ORF, "Activator of the phosphotyrosyl phosphatase activity of PP2A,peptidyl-prolyl cis/trans-isomerase; regulates G1 phase progression, the osmoresponse, microtubule dynamics; subunit of the Tap42p-Pph21p-Rrd2p complex" |
| 5543 | YPL152W-A | YPL152W-A SGDID:S000028721, Chr XVI from 264601-264699, Uncharacterized ORF, "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 5544 | YPL153C | RAD53 SGDID:S000006074, Chr XVI from 264191-261726, reverse complement, Verified ORF, "Protein kinase, required for cell-cycle arrest in response to DNA damage; activated by trans autophosphorylation when interacting with hyperphosphorylated Rad9p; also interacts with ARS1 and plays a role in initiation of DNA replication" |
| 5545 | YPL154C | PEP4 SGDID:S000006075, Chr XVI from 260930-259713, reverse complement, Verified ORF, "Vacuolar aspartyl protease (proteinase A), required for the posttranslational precursor maturation of vacuolar proteinases; important for protein turnover after oxidative damage; synthesized as a zymogen, self-activates" |
| 5546 | YPL155C | KIP2 SGDID:S000006076, Chr XVI from 259335-257215, reverse complement, Verified ORF, "Kinesin-related motor protein involved in mitotic spindle positioning, stabilizes microtubules by targeting Bik1p to the plus end; Kip2p levels are controlled during the cell cycle" |
| 5547 | YPL156C | PRM4 SGDID:S000006077, Chr XVI from 256766-255912, reverse complement, Verified ORF, "Pheromone-regulated protein, predicted to have 1 transmembrane segment; transcriptionally regulated by Ste12p during mating and by Cat8p during the diauxic shift" |
| 5548 | YPL157W | TGS1 SGDID:S000006078, Chr XVI from 254813-255760, Verified ORF, "Trimethyl guanosine synthase, conserved nucleolar methyl transferase responsible for conversion of the m(7)G cap structure of snRNAs and snoRNAs to m(2,2,7)G; also required for ribosome synthesis and nucleolar morphology" |
| 5549 | YPL158C | YPL158C SGDID:S000006079, Chr XVI from 254309-252033, reverse complement, Uncharacterized ORF, "Protein of unknown function; null mutant displays increased frequency of mitochondrial genome loss (petite formation) and reduced growth rate in minimal glycerol media" |
| 5550 | YPL159C | PET20 SGDID:S000006080, Chr XVI from 251667-250906, reverse complement, Verified ORF, "Mitochondrial protein, required for respiratory growth under some conditions and for stability of the mitochondrial genome" |
| 5551 | YPL160W | CDC60 SGDID:S000006081, Chr XVI from 246989-250261, Verified ORF, "Cytosolic leucyl tRNA synthetase, ligates leucine to the appropriate tRNA" |
| 5552 | YPL161C | BEM4 SGDID:S000006082, Chr XVI from 246219-244318, reverse complement, Verified ORF, "Protein involved in establishment of cell polarity and bud emergence; interacts with the Rho1p small GTP-binding protein and with the Rho-type GTPase Cdc42p; involved in maintenance of proper telomere length" |
| 5553 | YPL162C | YPL162C SGDID:S000006083, Chr XVI from 244026-243205, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the membrane of vacuole with cell cycle-correlated morphology" |
| 5554 | YPL163C | SVS1 SGDID:S000006084, Chr XVI from 242699-241917, reverse complement, Verified ORF, "Cell wall and vacuolar protein, required for wild-type resistance to vanadate" |
| 5555 | YPL164C | MLH3 SGDID:S000006085, Chr XVI from 241496-239349, reverse complement, Verified ORF, "Protein involved in DNA mismatch repair and crossing-over during meiotic recombination; forms a complex with Mlh1p; mammalian homolog is implicated mammalian microsatellite instability" |
| 5556 | YPL165C | SET6 SGDID:S000006086, Chr XVI from 239076-237955, reverse complement, Verified ORF, "Protein of unknown function; deletion heterozygote is sensitive to compounds that target ergosterol biosynthesis, may be involved in compound availability" |
| 5557 | YPL166W | ATG29 SGDID:S000006087, Chr XVI from 237337-237978, Verified ORF, "Protein specifically required for autophagy; may function in autophagosome formation at the pre-autophagosomal structure in collaboration with other autophagy proteins" |
| 5558 | YPL167C | REV3 SGDID:S000006088, Chr XVI from 237106-232592, reverse complement, Verified ORF, "Catalytic subunit of DNA polymerase zeta, which is involved in DNA repair and translesion synthesis; required for mutagenesis induced by DNA damage" |
| 5559 | YPL168W | YPL168W SGDID:S000006089, Chr XVI from 231216-232508, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; expression may be cell cycle-regulated" |
| 5560 | YPL169C | MEX67 SGDID:S000006090, Chr XVI from 230837-229038, reverse complement, Verified ORF, "Poly(A)RNA binding protein involved in nuclear mRNA export, component of the nuclear pore; ortholog of human TAP" |
| 5561 | YPL170W | DAP1 SGDID:S000006091, Chr XVI from 228313-228771, Verified ORF, "Heme-binding protein involved in regulation of cytochrome P450 protein Erg11p; damage response protein, related to mammalian membrane progesterone receptors; mutations lead to defects in telomeres, mitochondria, and sterol synthesis" |
| 5562 | YPL171C | OYE3 SGDID:S000006092, Chr XVI from 227370-226168, reverse complement, Verified ORF, "Widely conserved NADPH oxidoreductase containing flavin mononucleotide (FMN), homologous to Oye2p with slight differences in ligand binding and catalytic properties; may be involved in sterol metabolism" |
| 5563 | YPL172C | COX10 SGDID:S000006093, Chr XVI from 225740-224352, reverse complement, Verified ORF, "Heme A:farnesyltransferase, catalyzes the first step in the conversion of protoheme to the heme A prosthetic group required for cytochrome c oxidase activity; human ortholog is associated with mitochondrial disorders" |
| 5564 | YPL173W | MRPL40 SGDID:S000006094, Chr XVI from 223142-224035, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 5565 | YPL174C | NIP100 SGDID:S000006095, Chr XVI from 222772-220166, reverse complement, Verified ORF, "Large subunit of the dynactin complex, which is involved in partitioning the mitotic spindle between mother and daughter cells; putative ortholog of mammalian p150(glued)" |
| 5566 | YPL175W | SPT14 SGDID:S000006096, Chr XVI from 218629-218645,218746-220087, Verified ORF, "UDP-GlcNAc-binding and catalytic subunit of the enzyme that mediates the first step in glycosylphosphatidylinositol (GPI) biosynthesis, mutations cause defects in transcription and in biogenesis of cell wall proteins" |
| 5567 | YPL176C | TRE1 SGDID:S000006097, Chr XVI from 218362-216011, reverse complement, Verified ORF, "Plasma membrane protein that binds to Bsd2p and regulates ubiquitylation and vacuolar degradation of the metal transporter Smf1p; function is redundant with that of Tre2p; has similarity to transferrin receptors" |
| 5568 | YPL177C | CUP9 SGDID:S000006098, Chr XVI from 213961-213041, reverse complement, Verified ORF, "Homeodomain-containing transcriptional repressor of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription" |
| 5569 | YPL178W | CBC2 SGDID:S000006099, Chr XVI from 212157-212783, Verified ORF, "Small subunit of the heterodimeric cap binding complex that also contains Sto1p, component of the spliceosomal commitment complex; interacts with Npl3p, possibly to package mRNA for export from the nucleus; contains an RNA-binding motif" |
| 5570 | YPL179W | PPQ1 SGDID:S000006100, Chr XVI from 208156-209805, Verified ORF, "Putative protein serine/threonine phosphatase; null mutation enhances efficiency of translational suppressors" |
| 5571 | YPL180W | TCO89 SGDID:S000006101, Chr XVI from 205247-207646, Verified ORF, "Subunit of TORC1 (Tor1p or Tor2p-Kog1p-Lst8p-Tco89p), a complex that regulates growth in response to nutrient availability; cooperates with Ssd1p in the maintenance of cellular integrity; deletion strains are hypersensitive to rapamycin" |
| 5572 | YPL181W | CTI6 SGDID:S000006102, Chr XVI from 203420-204940, Verified ORF, "Protein that relieves transcriptional repression by binding to the Cyc8p-Tup1p corepressor and recruiting the SAGA complex to the repressed promoter; contains a PHD finger domain" |
| 5573 | YPL183C | RTT10 SGDID:S000006104, Chr XVI from 202535-199494, reverse complement, Verified ORF, "Cytoplasmic protein with a role in regulation of Ty1 transposition" |
| 5574 | YPL183W-A | YPL183W-A SGDID:S000007224, Chr XVI from 199094-199375, Uncharacterized ORF, "Homolog of the prokaryotic ribosomal protein L36, likely to be a mitochondrial ribosomal protein coded in the nuclear genome; null mutation suppresses cdc13-1 temperature sensitivity" |
| 5575 | YPL184C | YPL184C SGDID:S000006105, Chr XVI from 197787-195949, reverse complement, Uncharacterized ORF, "Putative RNA binding protein" |
| 5576 | YPL186C | UIP4 SGDID:S000006107, Chr XVI from 195425-194511, reverse complement, Verified ORF, "Protein that interacts with Ulp1p, a Ubl (ubiquitin-like protein)-specific protease for Smt3p protein conjugates; detected in a phosphorylated state in the mitochondrial outer membrane; also detected in ER and nuclear envelope" |
| 5577 | YPL187W | MF(ALPHA)1 SGDID:S000006108, Chr XVI from 193647-194144, Verified ORF, "Mating pheromone alpha-factor, made by alpha cells; interacts with mating type a cells to induce cell cycle arrest and other responses leading to mating; also encoded by MF(ALPHA)2, although MF(ALPHA)1 produces most alpha-factor" |
| 5578 | YPL188W | POS5 SGDID:S000006109, Chr XVI from 191405-192649, Verified ORF, "Mitochondrial NADH kinase, phosphorylates NADH; also phosphorylates NAD(+) with lower specificity; required for the response to oxidative stress" |
| 5579 | YPL189C-A | YPL189C-A SGDID:S000028527, Chr XVI from 188512-188306, reverse complement, Uncharacterized ORF, "Putative cytochrome oxidase assembly factor; identified by homology to Ashbya gossypii; null mutation results in respiratory deficiency with specific loss of cytochrome oxidase activity" |
| 5580 | YPL189W | GUP2 SGDID:S000006110, Chr XVI from 189153-190982, Verified ORF, "Probable membrane protein with a possible role in proton symport of glycerol; member of the MBOAT family of putative membrane-bound O-acyltransferases; Gup1p homolog" |
| 5581 | YPL190C | NAB3 SGDID:S000006111, Chr XVI from 187724-185316, reverse complement, Verified ORF, "Single stranded RNA binding protein; acidic ribonucleoprotein; required for termination of non-poly(A) transcripts and efficient splicing; interacts with Nrd1p" |
| 5582 | YPL191C | YPL191C SGDID:S000006112, Chr XVI from 184678-183596, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; diploid deletion strain exhibits high budding index; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 5583 | YPL192C | PRM3 SGDID:S000006113, Chr XVI from 183055-182654, reverse complement, Verified ORF, "Pheromone-regulated protein required for karyogamy; localizes to the inner membrane of the nuclear envelope" |
| 5584 | YPL193W | RSA1 SGDID:S000006114, Chr XVI from 181402-182547, Verified ORF, "Protein involved in the assembly of 60S ribosomal subunits; functionally interacts with Dbp6p; functions in a late nucleoplasmic step of the assembly" |
| 5585 | YPL194W | DDC1 SGDID:S000006115, Chr XVI from 179276-181114, Verified ORF, "DNA damage checkpoint protein, part of a PCNA-like complex required for DNA damage response, required for pachytene checkpoint to inhibit cell cycle in response to unrepaired recombination intermediates; potential Cdc28p substrate" |
| 5586 | YPL195W | APL5 SGDID:S000006116, Chr XVI from 176222-179020, Verified ORF, "Delta adaptin-like subunit of the clathrin associated protein complex (AP-3); functions in transport of alkaline phosphatase to the vacuole via the alternate pathway, suppressor of loss of casein kinase 1 function" |
| 5587 | YPL196W | OXR1 SGDID:S000006117, Chr XVI from 175042-175863, Verified ORF, "Protein of unknown function required for normal levels of resistance to oxidative damage, null mutants are sensitive to hydrogen peroxide; member of a conserved family of proteins found in eukaryotes but not in prokaryotes" |
| 5588 | YPL198W | RPL7B SGDID:S000006119, Chr XVI from 173151-173161,173571-173664,174072-174701, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl7Ap and has similarity to E. coli L30 and rat L7 ribosomal proteins; contains a conserved C-terminal Nucleic acid Binding Domain (NDB2)" |
| 5589 | YPL199C | YPL199C SGDID:S000006120, Chr XVI from 172754-172032, reverse complement, Uncharacterized ORF, "Hypothetical protein" |
| 5590 | YPL200W | CSM4 SGDID:S000006121, Chr XVI from 171483-171953, Verified ORF, "Protein required for accurate chromosome segregation during meiosis" |
| 5591 | YPL201C | YIG1 SGDID:S000006122, Chr XVI from 171154-169769, reverse complement, Verified ORF, "Protein that interacts with glycerol 3-phosphatase and plays a role in anaerobic glycerol production; localizes to the nucleus and cytosol" |
| 5592 | YPL202C | AFT2 SGDID:S000006123, Chr XVI from 169337-168087, reverse complement, Verified ORF, "Iron-regulated transcriptional activator; activates genes involved in intracellular iron use and required for iron homeostasis and resistance to oxidative stress; similar to Aft1p" |
| 5593 | YPL203W | TPK2 SGDID:S000006124, Chr XVI from 166255-167397, Verified ORF, "cAMP-dependent protein kinase catalytic subunit; promotes vegetative growth in response to nutrients via the Ras-cAMP signaling pathway; inhibited by regulatory subunit Bcy1p in the absence of cAMP; partially redundant with Tpk1p and Tpk3p" |
| 5594 | YPL204W | HRR25 SGDID:S000006125, Chr XVI from 164275-165759, Verified ORF, "Protein kinase involved in regulating diverse events including vesicular trafficking, DNA repair, and chromosome segregation; binds the CTD of RNA pol II; homolog of mammalian casein kinase 1delta (CK1delta)" |
| 5595 | YPL206C | PGC1 SGDID:S000006127, Chr XVI from 163596-162631, reverse complement, Uncharacterized ORF, "Phosphatidyl Glycerol phospholipase C; regulates the phosphatidylglycerol (PG) content via a phospholipase C-type degradation mechanism; contains glycerophosphodiester phosphodiesterase motifs" |
| 5596 | YPL207W | TYW1 SGDID:S000006128, Chr XVI from 159908-162340, Verified ORF, "Protein required for the synthesis of wybutosine, a modified guanosine found at the 3'-position adjacent to the anticodon of phenylalanine tRNA which supports reading frame maintenance by stabilizing codon-anticodon interactions" |
| 5597 | YPL208W | RKM1 SGDID:S000006129, Chr XVI from 157841-159592, Verified ORF, "SET-domain lysine-N-methyltransferase, catalyzes the formation of dimethyllysine residues on the large ribsomal subunit protein L23a (RPL23A and RPL23B)" |
| 5598 | YPL209C | IPL1 SGDID:S000006130, Chr XVI from 157592-156489, reverse complement, Verified ORF, "Aurora kinase involved in regulating kinetochore-microtubule attachments; helps maintain condensed chromosomes during anaphase and early telophase; associates with Sli15p, which promotes Ipl1p association with mitotic spindle" |
| 5599 | YPL210C | SRP72 SGDID:S000006131, Chr XVI from 156211-154289, reverse complement, Verified ORF, "Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane" |
| 5600 | YPL211W | NIP7 SGDID:S000006132, Chr XVI from 153494-154039, Verified ORF, "Nucleolar protein required for 60S ribosome subunit biogenesis, constituent of 66S pre-ribosomal particles; physically interacts with Nop8p and the exosome subunit Rrp43p" |
| 5601 | YPL212C | PUS1 SGDID:S000006133, Chr XVI from 153148-151514, reverse complement, Verified ORF, "tRNA:pseudouridine synthase, introduces pseudouridines at positions 26-28, 34-36, 65, and 67 of tRNA; nuclear protein that appears to be involved in tRNA export; also acts on U2 snRNA" |
| 5602 | YPL213W | LEA1 SGDID:S000006134, Chr XVI from 150613-151329, Verified ORF, "Component of U2 snRNP; disruption causes reduced U2 snRNP levels; physically interacts with Msl1p; invovled in telomere maintenance; putative homolog of human U2A' snRNP protein" |
| 5603 | YPL214C | THI6 SGDID:S000006135, Chr XVI from 150190-148568, reverse complement, Verified ORF, "Bifunctional enzyme with thiamine-phosphate pyrophosphorylase and 4-methyl-5-beta-hydroxyethylthiazole kinase activities, required for thiamine biosynthesis; GFP-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 5604 | YPL215W | CBP3 SGDID:S000006136, Chr XVI from 147415-148422, Verified ORF, "Mitochondrial protein required for assembly of ubiquinol cytochrome-c reductase complex (cytochrome bc1 complex); interacts with Cbp4p and function is partially redundant with that of Cbp4p" |
| 5605 | YPL216W | YPL216W SGDID:S000006137, Chr XVI from 143820-147128, Uncharacterized ORF, "Putative protein of unknown function; YPL216W is not an essential gene" |
| 5606 | YPL217C | BMS1 SGDID:S000006138, Chr XVI from 143170-139619, reverse complement, Verified ORF, "Essential conserved nucleolar GTP-binding protein required for synthesis of 40S ribosomal subunits and for processing of the 35S pre-rRNA at sites A0, A1, and A2; interacts with Rcl1p, has similarity to Tsr1p" |
| 5607 | YPL218W | SAR1 SGDID:S000006139, Chr XVI from 138697-138724,138864-139408, Verified ORF, "GTPase, GTP-binding protein of the ARF family, component of COPII coat of vesicles; required for transport vesicle formation during ER to Golgi protein transport" |
| 5608 | YPL219W | PCL8 SGDID:S000006140, Chr XVI from 136749-138227, Verified ORF, "Cyclin, interacts with Pho85p cyclin-dependent kinase (Cdk) to phosphorylate and regulate glycogen synthase, also activates Pho85p for Glc8p phosphorylation" |
| 5609 | YPL220W | RPL1A SGDID:S000006141, Chr XVI from 135789-136442, Verified ORF, "N-terminally acetylated protein component of the large (60S) ribosomal subunit, nearly identical to Rpl1Bp and has similarity to E. coli L1 and rat L10a ribosomal proteins; rpl1a rpl1b double null mutation is lethal" |
| 5610 | YPL221W | FLC1 SGDID:S000006142, Chr XVI from 133042-135423, Verified ORF, "Putative FAD transporter; required for uptake of FAD into endoplasmic reticulum; involved in cell wall maintenance" |
| 5611 | YPL222W | YPL222W SGDID:S000006143, Chr XVI from 130161-132227, Uncharacterized ORF, "Putative protein of unknown function; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 5612 | YPL223C | GRE1 SGDID:S000006144, Chr XVI from 129137-128631, reverse complement, Verified ORF, "Hydrophilin of unknown function; stress induced (osmotic, ionic, oxidative, heat shock and heavy metals); regulated by the HOG pathway" |
| 5613 | YPL224C | MMT2 SGDID:S000006145, Chr XVI from 128087-126738, reverse complement, Verified ORF, "Putative metal transporter involved in mitochondrial iron accumulation; closely related to Mmt1p" |
| 5614 | YPL225W | YPL225W SGDID:S000006146, Chr XVI from 126006-126446, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 5615 | YPL226W | NEW1 SGDID:S000006147, Chr XVI from 121767-125357, Verified ORF, "ATP binding cassette family member; Asn/Gln-rich rich region supports [NU+] prion formation, susceptibility to [PSI+] prion induction and aggregation of a fragment of the human Machado-Joseph Disease protein" |
| 5616 | YPL227C | ALG5 SGDID:S000006148, Chr XVI from 121167-120163, reverse complement, Verified ORF, "UDP-glucose:dolichyl-phosphate glucosyltransferase, involved in asparagine-linked glycosylation in the endoplasmic reticulum" |
| 5617 | YPL228W | CET1 SGDID:S000006149, Chr XVI from 118382-120031, Verified ORF, "Beta (RNA 5'-triphosphatase) subunit of the mRNA capping enzyme, a heterodimer (the other subunit is CEG1, a guanylyltransferase) involved in adding the 5' cap to mRNA; the mammalian enzyme is a single bifunctional polypeptide" |
| 5618 | YPL229W | YPL229W SGDID:S000006150, Chr XVI from 117067-117687, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; YPL229W is not an essential gene" |
| 5619 | YPL230W | USV1 SGDID:S000006151, Chr XVI from 115312-116487, Verified ORF, "Putative transcription factor containing a C2H2 zinc finger; mutation affects transcriptional regulation of genes involved in protein folding, ATP binding, and cell wall biosynthesis" |
| 5620 | YPL231W | FAS2 SGDID:S000006152, Chr XVI from 108652-114315, Verified ORF, "Alpha subunit of fatty acid synthetase, which catalyzes the synthesis of long-chain saturated fatty acids; contains beta-ketoacyl reductase and beta-ketoacyl synthase activities; phosphorylated" |
| 5621 | YPL232W | SSO1 SGDID:S000006153, Chr XVI from 107275-108147, Verified ORF, "Plasma membrane t-SNARE involved in fusion of secretory vesicles at the plasma membrane and in vesicle fusion during sporulation; forms a complex with Sec9p that binds v-SNARE Snc2p; syntaxin homolog; functionally redundant with Sso2p" |
| 5622 | YPL233W | NSL1 SGDID:S000006154, Chr XVI from 106172-106822, Verified ORF, "Essential component of the MIND kinetochore complex (Mtw1p Including Nnf1p-Nsl1p-Dsn1p) which joins kinetochore subunits contacting DNA to those contacting microtubules; required for accurate chromosome segregation" |
| 5623 | YPL234C | TFP3 SGDID:S000006155, Chr XVI from 105440-104946, reverse complement, Verified ORF, "Vacuolar ATPase V0 domain subunit c', involved in proton transport activity; hydrophobic integral membrane protein (proteolipid) containing four transmembrane segments; N and C termini are in the vacuolar lumen" |
| 5624 | YPL235W | RVB2 SGDID:S000006156, Chr XVI from 103232-104647, Verified ORF, "Essential protein involved in transcription regulation; component of chromatin remodeling complexes; required for assembly and function of the INO80 complex; member of the RUVB-like protein family" |
| 5625 | YPL236C | YPL236C SGDID:S000006157, Chr XVI from 102702-101608, reverse complement, Uncharacterized ORF, "Putative protein kinase that exhibits Akr1p-dependent palmitoylation" |
| 5626 | YPL237W | SUI3 SGDID:S000006158, Chr XVI from 100496-101353, Verified ORF, "Beta subunit of the translation initiation factor eIF2, involved in the identification of the start codon; proposed to be involved in mRNA binding" |
| 5627 | YPL239W | YAR1 SGDID:S000006160, Chr XVI from 99484-100086, Verified ORF, "Cytoplasmic ankyrin-repeat containing protein of unknown function, proposed to link the processes of 40S ribosomal subunit biogenesis and adaptation to osmotic and oxidative stress; expression repressed by heat shock" |
| 5628 | YPL240C | HSP82 SGDID:S000006161, Chr XVI from 98625-96496, reverse complement, Verified ORF, "Hsp90 chaperone required for pheromone signaling and negative regulation of Hsf1p; docks with Tom70p for mitochondrial preprotein delivery; promotes telomerase DNA binding and nucleotide addition; interacts with Cns1p, Cpr6p, Cpr7p, Sti1p" |
| 5629 | YPL241C | CIN2 SGDID:S000006162, Chr XVI from 96258-96234,96153-95372, reverse complement, Verified ORF, "GTPase-activating protein (GAP) for Cin4p; tubulin folding factor C involved in beta-tubulin (Tub2p) folding; mutants display increased chromosome loss and benomyl sensitivity; deletion complemented by human GAP, retinitis pigmentosa 2" |
| 5630 | YPL242C | IQG1 SGDID:S000006163, Chr XVI from 95109-90622, reverse complement, Verified ORF, "Essential protein required for determination of budding pattern, promotes localization of axial markers Bud4p and Cdc12p and functionally interacts with Sec3p, localizes to the contractile ring during anaphase, member of the IQGAP family" |
| 5631 | YPL243W | SRP68 SGDID:S000006164, Chr XVI from 88517-90316, Verified ORF, "Core component of the signal recognition particle (SRP) ribonucleoprotein (RNP) complex that functions in targeting nascent secretory proteins to the endoplasmic reticulum (ER) membrane" |
| 5632 | YPL244C | HUT1 SGDID:S000006165, Chr XVI from 88033-87014, reverse complement, Verified ORF, "Protein with a role in UDP-galactose transport to the Golgi lumen, has similarity to human UDP-galactose transporter UGTrel1, exhibits a genetic interaction with S. cerevisiae ERO1" |
| 5633 | YPL245W | YPL245W SGDID:S000006166, Chr XVI from 85586-86950, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the nucleus and the cytoplasm" |
| 5634 | YPL246C | RBD2 SGDID:S000006167, Chr XVI from 85297-84509, reverse complement, Verified ORF, "Possible rhomboid protease, has similarity to eukaryotic rhomboid proteases including Pcp1p" |
| 5635 | YPL247C | YPL247C SGDID:S000006168, Chr XVI from 84196-82625, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; similar to the petunia WD repeat protein an11; YPL247C is not an essential gene" |
| 5636 | YPL248C | GAL4 SGDID:S000006169, Chr XVI from 82356-79711, reverse complement, Verified ORF, "DNA-binding transcription factor required for the activation of the GAL genes in response to galactose; repressed by Gal80p and activated by Gal3p" |
| 5637 | YPL249C | GYP5 SGDID:S000006170, Chr XVI from 79353-76669, reverse complement, Verified ORF, "GTPase-activating protein (GAP) for yeast Rab family members, involved in ER to Golgi trafficking; exhibits GAP activity toward Ypt1p that is stimulated by Gyl1p, also acts on Sec4p; interacts with Gyl1p, Rvs161p and Rvs167p" |
| 5638 | YPL249C-A | RPL36B SGDID:S000006438, Chr XVI from 76239-76224,75985-75699, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl36Ap and has similarity to rat L36 ribosomal protein; binds to 5.8 S rRNA" |
| 5639 | YPL250C | ICY2 SGDID:S000006171, Chr XVI from 74719-74309, reverse complement, Verified ORF, "Protein of unknown function; mobilized into polysomes upon a shift from a fermentable to nonfermentable carbon source; potential Cdc28p substrate" |
| 5640 | YPL252C | YAH1 SGDID:S000006173, Chr XVI from 73881-73363, reverse complement, Verified ORF, "Ferredoxin of the mitochondrial matrix required for formation of cellular iron-sulfur proteins; involved in heme A biosynthesis; homologous to human adrenodoxin" |
| 5641 | YPL253C | VIK1 SGDID:S000006174, Chr XVI from 73006-71063, reverse complement, Verified ORF, "Protein that forms a complex with Kar3p at the spindle pole body, possible regulator of Kar3p function in microtubule-mediated processes; required for sister chromatid cohesion; has similarity to Cik1p" |
| 5642 | YPL254W | HFI1 SGDID:S000006175, Chr XVI from 69485-70951, Verified ORF, "Adaptor protein required for structural integrity of the SAGA complex, a histone acetyltransferase-coactivator complex that is involved in global regulation of gene expression through acetylation and transcription functions" |
| 5643 | YPL255W | BBP1 SGDID:S000006176, Chr XVI from 67725-68882, Verified ORF, "Protein required for the spindle pole body (SPB) duplication, localized at the central plaque periphery; forms a complex with a nuclear envelope protein Mps2p and SPB components Spc29p and Kar1p; required for mitotic functions of Cdc5p" |
| 5644 | YPL256C | CLN2 SGDID:S000006177, Chr XVI from 66614-64977, reverse complement, Verified ORF, "G1 cyclin involved in regulation of the cell cycle; activates Cdc28p kinase to promote the G1 to S phase transition; late G1 specific expression depends on transcription factor complexes, MBF (Swi6p-Mbp1p) and SBF (Swi6p-Swi4p)" |
| 5645 | YPL257W | YPL257W SGDID:S000006178, Chr XVI from 63279-63860, Uncharacterized ORF, "Putative protein of unknown function;; homozygous diploid deletion strain exhibits low budding index; physically interacts with Hsp82p; YPL257W is not an essential gene" |
| 5646 | YPL257W-A | YPL257W-A SGDID:S000007357, Chr XVI from 56748-58070, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 5647 | YPL257W-B | YPL257W-B SGDID:S000007358, Chr XVI from 56748-58052,58054-62016, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 5648 | YPL258C | THI21 SGDID:S000006179, Chr XVI from 55153-53498, reverse complement, Verified ORF, "Hydroxymethylpyrimidine phosphate kinase, involved in the last steps in thiamine biosynthesis; member of a gene family with THI20 and THI22; functionally redundant with Thi20p" |
| 5649 | YPL259C | APM1 SGDID:S000006180, Chr XVI from 52671-51244, reverse complement, Verified ORF, "Mu1-like medium subunit of the clathrin-associated protein complex (AP-1); binds clathrin; involved in clathrin-dependent Golgi protein sorting" |
| 5650 | YPL260W | YPL260W SGDID:S000006181, Chr XVI from 49303-50958, Uncharacterized ORF, "Putative substrate of cAMP-dependent protein kinase (PKA); green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and nucleus; YPL260W is not an essential gene" |
| 5651 | YPL262W | FUM1 SGDID:S000006183, Chr XVI from 47336-48802, Verified ORF, "Fumarase, converts fumaric acid to L-malic acid in the TCA cycle; cytosolic and mitochondrial localization determined by the N-terminal mitochondrial targeting sequence and protein conformation; phosphorylated in mitochondria" |
| 5652 | YPL263C | KEL3 SGDID:S000006184, Chr XVI from 46506-44551, reverse complement, Verified ORF, "Cytoplasmic protein of unknown function" |
| 5653 | YPL264C | YPL264C SGDID:S000006185, Chr XVI from 44344-43283, reverse complement, Uncharacterized ORF, "Putative membrane protein of unknown function; physically interacts with Hsp82p; YPL264C is not an essential gene" |
| 5654 | YPL265W | DIP5 SGDID:S000006186, Chr XVI from 41043-42869, Verified ORF, "Dicarboxylic amino acid permease, mediates high-affinity and high-capacity transport of L-glutamate and L-aspartate; also a transporter for Gln, Asn, Ser, Ala, and Gly" |
| 5655 | YPL266W | DIM1 SGDID:S000006187, Chr XVI from 39121-40077, Verified ORF, "Essential 18S rRNA dimethylase (dimethyladenosine transferase), responsible for conserved m6(2)Am6(2)A dimethylation in 3'-terminal loop of 18S rRNA, part of 90S and 40S pre-particles in nucleolus, involved in pre-ribosomal RNA processing" |
| 5656 | YPL267W | ACM1 SGDID:S000006188, Chr XVI from 38169-38798, Verified ORF, "Cell cycle regulated protein of unknown function; associated with Cdh1p and may supress the APC/C[Cdh1]-mediated proteolysis of mitotic cyclins" |
| 5657 | YPL268W | PLC1 SGDID:S000006189, Chr XVI from 35236-37845, Verified ORF, "Phospholipase C, hydrolyzes phosphatidylinositol 4,5-biphosphate (PIP2) to generate the signaling molecules inositol 1,4,5-triphosphate (IP3) and 1,2-diacylglycerol (DAG); involved in regulating many cellular processes" |
| 5658 | YPL269W | KAR9 SGDID:S000006190, Chr XVI from 33013-34947, Verified ORF, "Karyogamy protein required for correct positioning of the mitotic spindle and for orienting cytoplasmic microtubules, localizes at the shmoo tip in mating cells and at the tip of the growing bud in small-budded cells through anaphase" |
| 5659 | YPL270W | MDL2 SGDID:S000006191, Chr XVI from 30482-32803, Verified ORF, "Mitochondrial inner membrane half-type ATP-binding cassette (ABC) transporter" |
| 5660 | YPL271W | ATP15 SGDID:S000006192, Chr XVI from 30079-30267, Verified ORF, "Epsilon subunit of the F1 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis; phosphorylated" |
| 5661 | YPL272C | YPL272C SGDID:S000006193, Chr XVI from 28164-26611, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; gene expression induced in response to ketoconazole; YPL272C is not an essential gene" |
| 5662 | YPL273W | SAM4 SGDID:S000006194, Chr XVI from 25087-26064, Verified ORF, "S-adenosylmethionine-homocysteine methyltransferase, functions along with Mht1p in the conversion of S-adenosylmethionine (AdoMet) to methionine to control the methionine/AdoMet ratio" |
| 5663 | YPL274W | SAM3 SGDID:S000006195, Chr XVI from 22938-24701, Verified ORF, "High-affinity S-adenosylmethionine permease, required for utilization of S-adenosylmethionine as a sulfur source; has similarity to S-methylmethionine permease Mmp1p" |
| 5664 | YPL277C | YPL277C SGDID:S000006198, Chr XVI from 16868-15405, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; localized to the membranes; gene expression regulated by copper levels" |
| 5665 | YPL278C | YPL278C SGDID:S000006199, Chr XVI from 15355-15053, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; gene expression regulated by copper levels" |
| 5666 | YPL279C | YPL279C SGDID:S000006200, Chr XVI from 14355-13228, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 5667 | YPL280W | HSP32 SGDID:S000006201, Chr XVI from 11887-12600, Uncharacterized ORF, "Possible chaperone and cysteine protease with similarity to E. coli Hsp31 and S. cerevisiae Hsp31p, Hsp33p, and Sno4p; member of the DJ-1/ThiJ/PfpI superfamily, which includes human DJ-1 involved in Parkinson's disease" |
| 5668 | YPL281C | ERR2 SGDID:S000006202, Chr XVI from 10870-9557, reverse complement, Verified ORF, "Protein of unknown function, has similarity to enolases" |
| 5669 | YPL282C | YPL282C SGDID:S000006203, Chr XVI from 8427-7933, reverse complement, Uncharacterized ORF, "Hypothetical protein" |
| 5670 | YPL283C | YRF1-7 SGDID:S000006204, Chr XVI from 6007-5989,5840-280, reverse complement, Verified ORF, "Helicase encoded by the Y' element of subtelomeric regions, highly expressed in the mutants lacking the telomerase component TLC1; potentially phosphorylated by Cdc28p" |
| 5671 | YPR001W | CIT3 SGDID:S000006205, Chr XVI from 556374-557834, Verified ORF, "Dual specificity mitochondrial citrate and methylcitrate synthase; catalyzes the condensation of acetyl-CoA and oxaloacetate to form citrate and that of propionyl-CoA and oxaloacetate to form 2-methylcitrate" |
| 5672 | YPR002W | PDH1 SGDID:S000006206, Chr XVI from 558382-559932, Verified ORF, "Mitochondrial protein that participates in respiration, induced by diauxic shift; homologous to E. coli PrpD, may take part in the conversion of 2-methylcitrate to 2-methylisocitrate" |
| 5673 | YPR003C | YPR003C SGDID:S000006207, Chr XVI from 563765-561501, reverse complement, Uncharacterized ORF, "Putative sulfate permease; physically interacts with Hsp82p; green fluorescent protein (GFP)-fusion protein localizes to the ER; YPR003C is not an essential gene" |
| 5674 | YPR004C | YPR004C SGDID:S000006208, Chr XVI from 565038-564004, reverse complement, Verified ORF, "Protein with similarity to mammalian electron transfer flavoprotein complex subunit ETF-alpha; interacts with yeast frataxin Yfh1p; null mutant displays increased frequency of mitochondrial genome loss (petite formation)" |
| 5675 | YPR005C | HAL1 SGDID:S000006209, Chr XVI from 566668-565784, reverse complement, Verified ORF, "Cytoplasmic protein involved in halotolerance; decreases intracellular Na+ (via Ena1p) and increases intracellular K+ by decreasing efflux; expression repressed by Ssn6p-Tup1p and Sko1p and induced by NaCl, KCl, and sorbitol through Gcn4p" |
| 5676 | YPR006C | ICL2 SGDID:S000006210, Chr XVI from 568993-567266, reverse complement, Verified ORF, "2-methylisocitrate lyase of the mitochondrial matrix, functions in the methylcitrate cycle to catalyze the conversion of 2-methylisocitrate to succinate and pyruvate; ICL2 transcription is repressed by glucose and induced by ethanol" |
| 5677 | YPR007C | REC8 SGDID:S000006211, Chr XVI from 571375-569333, reverse complement, Verified ORF, "Meiosis-specific component of sister chromatid cohesion complex; maintains cohesion between sister chromatids during meiosis I; maintains cohesion between centromeres of sister chromatids until meiosis II; homolog of S. pombe Rec8p" |
| 5678 | YPR008W | HAA1 SGDID:S000006212, Chr XVI from 573015-575099, Verified ORF, "Transcriptional activator involved in the transcription of TPO2, HSP30 and other genes encoding membrane stress proteins; involved in adaptation to weak acid stress" |
| 5679 | YPR009W | SUT2 SGDID:S000006213, Chr XVI from 576549-577355, Verified ORF, "Putative transcription factor; multicopy suppressor of mutations that cause low activity of the cAMP/protein kinase A pathway; highly similar to Sut1p" |
| 5680 | YPR010C | RPA135 SGDID:S000006214, Chr XVI from 581193-577582, reverse complement, Verified ORF, "RNA polymerase I subunit A135" |
| 5681 | YPR010C-A | YPR010C-A SGDID:S000122558, Chr XVI from 582731-582699,582555-582370, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; conserved among Saccharomyces sensu stricto species" |
| 5682 | YPR011C | YPR011C SGDID:S000006215, Chr XVI from 584039-583059, reverse complement, Uncharacterized ORF, "Putative transporter, member of the mitochondrial carrier family; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 5683 | YPR013C | YPR013C SGDID:S000006217, Chr XVI from 585582-584629, reverse complement, Uncharacterized ORF, "Putative zinc finger protein; YPR013C is not an essential gene" |
| 5684 | YPR015C | YPR015C SGDID:S000006219, Chr XVI from 591023-590280, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 5685 | YPR016C | TIF6 SGDID:S000006220, Chr XVI from 593066-592329, reverse complement, Verified ORF, "Constituent of 66S pre-ribosomal particles, has similarity to human translation initiation factor 6 (eIF6); may be involved in the biogenesis and or stability of 60S ribosomal subunits" |
| 5686 | YPR017C | DSS4 SGDID:S000006221, Chr XVI from 593914-593483, reverse complement, Verified ORF, "Guanine nucleotide dissociation stimulator for Sec4p, functions in the post-Golgi secretory pathway; binds zinc, found both on membranes and in the cytosol" |
| 5687 | YPR018W | RLF2 SGDID:S000006222, Chr XVI from 594473-596293, Verified ORF, "Largest subunit (p90) of the Chromatin Assembly Complex (CAF-1) with Cac2p and Msi1p that assembles newly synthesized histones onto recently replicated DNA; involved in the maintenance of transcriptionally silent chromatin" |
| 5688 | YPR019W | MCM4 SGDID:S000006223, Chr XVI from 596747-599548, Verified ORF, "Essential helicase component of heterohexameric MCM2-7 complexes which bind pre-replication complexes on DNA and melt the DNA prior to replication; accumulates in the nucleus in G1; homolog of S. pombe Cdc21p" |
| 5689 | YPR020W | ATP20 SGDID:S000006224, Chr XVI from 599867-600214, Verified ORF, "Subunit g of the mitochondrial F1F0 ATP synthase; reversibly phosphorylated on two residues; unphosphorylated form is required for dimerization of the ATP synthase complex" |
| 5690 | YPR021C | AGC1 SGDID:S000006225, Chr XVI from 603354-600646, reverse complement, Verified ORF, "Mitochondrial amino acid transporter, acts both as a glutamate uniporter and as an aspartate-glutamate exchanger; involved in nitrogen metabolism and nitrogen compound biosynthesis" |
| 5691 | YPR022C | YPR022C SGDID:S000006226, Chr XVI from 607309-603908, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus and is induced in response to the DNA-damaging agent MMS" |
| 5692 | YPR023C | EAF3 SGDID:S000006227, Chr XVI from 610028-608823, reverse complement, Verified ORF, "Esa1p-associated factor, nonessential component of the NuA4 acetyltransferase complex, homologous to Drosophila dosage compensation protein MSL3; plays a role in regulating Ty1 transposition" |
| 5693 | YPR024W | YME1 SGDID:S000006228, Chr XVI from 610478-612721, Verified ORF, "Subunit, with Mgr1p, of the mitochondrial inner membrane i-AAA protease complex, which is responsible for degradation of unfolded or misfolded mitochondrial gene products; mutation causes an elevated rate of mitochondrial turnover" |
| 5694 | YPR025C | CCL1 SGDID:S000006229, Chr XVI from 614555-613374, reverse complement, Verified ORF, "Cyclin associated with protein kinase Kin28p, which is the TFIIH-associated carboxy-terminal domain (CTD) kinase involved in transcription initiation at RNA polymerase II promoters" |
| 5695 | YPR026W | ATH1 SGDID:S000006230, Chr XVI from 615376-619011, Verified ORF, "Acid trehalase required for utilization of extracellular trehalose" |
| 5696 | YPR027C | YPR027C SGDID:S000006231, Chr XVI from 621255-620422, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 5697 | YPR028W | YOP1 SGDID:S000006232, Chr XVI from 623524-623574,623708-624199, Verified ORF, "Membrane protein that interacts with Yip1p to mediate membrane traffic; overexpression results in cell death and accumulation of internal cell membranes; regulates vesicular traffic in stressed cells" |
| 5698 | YPR029C | APL4 SGDID:S000006233, Chr XVI from 626964-624466, reverse complement, Verified ORF, "Gamma-adaptin, large subunit of the clathrin-associated protein (AP-1) complex; binds clathrin; involved in vesicle mediated transport" |
| 5699 | YPR030W | CSR2 SGDID:S000006234, Chr XVI from 627877-631242, Verified ORF, "Nuclear protein with a potential regulatory role in utilization of galactose and nonfermentable carbon sources; overproduction suppresses the lethality at high temperature of a chs5 spa2 double null mutation; potential Cdc28p substrate" |
| 5700 | YPR031W | NTO1 SGDID:S000006235, Chr XVI from 631512-633758, Verified ORF, "Subunit of the NuA3 histone acetyltransferase complex that acetylates histone H3; contains PHD finger domain that interacts with methylated histone H3" |
| 5701 | YPR032W | SRO7 SGDID:S000006236, Chr XVI from 634120-637221, Verified ORF, "Effector of Rab GTPase Sec4p, forms a complex with Sec4p and t-SNARE Sec9p; involved in exocytosis and docking and fusion of post-Golgi vesicles with plasma membrane; homolog of Sro77p and Drosophila lgl tumor suppressor" |
| 5702 | YPR033C | HTS1 SGDID:S000006237, Chr XVI from 639016-637376, reverse complement, Verified ORF, "Cytoplasmic and mitochondrial histidine tRNA synthetase; encoded by a single nuclear gene that specifies two messages; efficient mitochondrial localization requires both a presequence and an amino-terminal sequence" |
| 5703 | YPR034W | ARP7 SGDID:S000006238, Chr XVI from 639522-640955, Verified ORF, "Component of both the SWI/SNF and RSC chromatin remodeling complexes; actin-related protein involved in transcriptional regulation" |
| 5704 | YPR035W | GLN1 SGDID:S000006239, Chr XVI from 642205-643317, Verified ORF, "Glutamine synthetase (GS), synthesizes glutamine from glutamate and ammonia; with Glt1p, forms the secondary pathway for glutamate biosynthesis from ammonia; expression regulated by nitrogen source and by amino acid limitation" |
| 5705 | YPR036W | VMA13 SGDID:S000006240, Chr XVI from 643833-645269, Verified ORF, "Subunit H of the eight-subunit V1 peripheral membrane domain of the vacuolar H+-ATPase (V-ATPase), an electrogenic proton pump found throughout the endomembrane system; serves as an activator or a structural stabilizer of the V-ATPase" |
| 5706 | YPR036W-A | YPR036W-A SGDID:S000028425, Chr XVI from 645947-646150, Verified ORF, "Protein of unknown function; transcription is regulated by Pdr1p" |
| 5707 | YPR037C | ERV2 SGDID:S000006241, Chr XVI from 647035-646445, reverse complement, Verified ORF, "Flavin-linked sulfhydryl oxidase localized to the endoplasmic reticulum lumen, involved in disulfide bond formation within the ER" |
| 5708 | YPR040W | TIP41 SGDID:S000006244, Chr XVI from 647302-648372, Verified ORF, "Protein that interacts physically and genetically with Tap42p, which regulates protein phosphatase 2A; component of the TOR (target of rapamycin) signaling pathway" |
| 5709 | YPR041W | TIF5 SGDID:S000006245, Chr XVI from 648701-649918, Verified ORF, "Translation initiation factor eIF-5; N-terminal domain functions as a GTPase-activating protein to mediate hydrolysis of ribosome-bound GTP; C-terminal domain is the core of ribosomal preinitiation complex formation" |
| 5710 | YPR042C | PUF2 SGDID:S000006246, Chr XVI from 653659-650432, reverse complement, Verified ORF, "Member of the PUF protein family, which is defined by the presence of Pumilio homology domains that confer RNA binding activity; preferentially binds mRNAs encoding membrane-associated proteins" |
| 5711 | YPR043W | RPL43A SGDID:S000006247, Chr XVI from 654163-654164,654568-654844, Verified ORF, "Protein component of the large (60S) ribosomal subunit, identical to Rpl43Bp and has similarity to rat L37a ribosomal protein; null mutation confers a dominant lethal phenotype" |
| 5712 | YPR045C | YPR045C SGDID:S000006249, Chr XVI from 656549-655137, reverse complement, Uncharacterized ORF, "Deletion mutant is synthetically lethal with MEN mutants" |
| 5713 | YPR046W | MCM16 SGDID:S000006250, Chr XVI from 656796-657341, Verified ORF, "Protein involved in kinetochore-microtubule mediated chromosome segregation; binds to centromere DNA" |
| 5714 | YPR047W | MSF1 SGDID:S000006251, Chr XVI from 657526-658935, Verified ORF, "Mitochondrial phenylalanyl-tRNA synthetase alpha subunit, active as a monomer, unlike the cytoplasmic subunit which is active as a dimer complexed to a beta subunit dimer; similar to the alpha subunit of E. coli phenylalanyl-tRNA synthetase" |
| 5715 | YPR048W | TAH18 SGDID:S000006252, Chr XVI from 659179-661050, Verified ORF, "Protein with a potential role in DNA replication; displays synthetic lethal genetic interaction with the pol3-13 allele of POL3, which encodes DNA polymerase delta" |
| 5716 | YPR049C | ATG11 SGDID:S000006253, Chr XVI from 664670-661134, reverse complement, Verified ORF, "Adapter protein for pexophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; directs receptor-bound cargo to the pro-autophagosomal structure (PAS) for packaging into vesicles; required for recruiting other proteins to the PAS" |
| 5717 | YPR051W | MAK3 SGDID:S000006255, Chr XVI from 664957-665487, Verified ORF, "Catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus" |
| 5718 | YPR052C | NHP6A SGDID:S000006256, Chr XVI from 665971-665690, reverse complement, Verified ORF, "High-mobility group non-histone chromatin protein, functionally redundant with Nhp6Bp; homologous to mammalian high mobility group proteins 1 and 2; acts to recruit transcription factor Rcs1p to certain promoters" |
| 5719 | YPR054W | SMK1 SGDID:S000006258, Chr XVI from 666277-667443, Verified ORF, "Middle sporulation-specific mitogen-activated protein kinase (MAPK) required for production of the outer spore wall layers; negatively regulates activity of the glucan synthase subunit Gsc2p" |
| 5720 | YPR055W | SEC8 SGDID:S000006259, Chr XVI from 667673-670870, Verified ORF, "Essential 121kDa subunit of the exocyst complex (Sec3p, Sec5p, Sec6p, Sec8p, Sec10p, Sec15p, Exo70p, and Exo84p), which has the essential function of mediating polarized targeting of secretory vesicles to active sites of exocytosis" |
| 5721 | YPR056W | TFB4 SGDID:S000006260, Chr XVI from 671123-672139, Verified ORF, "Subunit of TFIIH complex, involved in transcription initiation, similar to 34 kDa subunit of human TFIIH; interacts with Ssl1p" |
| 5722 | YPR057W | BRR1 SGDID:S000006261, Chr XVI from 672468-673493, Verified ORF, "snRNP protein component of spliceosomal snRNPs, required for pre-mRNA splicing and snRNP biogenesis; in null mutant newly-synthesized snRNAs are destabilized and 3'-end processing is slowed" |
| 5723 | YPR058W | YMC1 SGDID:S000006262, Chr XVI from 673748-674671, Verified ORF, "Mitochondrial protein, putative inner membrane transporter with a role in oleate metabolism and glutamate biosynthesis; member of the mitochondrial carrier (MCF) family; has similarity with Ymc2p" |
| 5724 | YPR060C | ARO7 SGDID:S000006264, Chr XVI from 675628-674858, reverse complement, Verified ORF, "Chorismate mutase, catalyzes the conversion of chorismate to prephenate to initiate the tyrosine/phenylalanine-specific branch of aromatic amino acid biosynthesis" |
| 5725 | YPR061C | JID1 SGDID:S000006265, Chr XVI from 676879-675974, reverse complement, Verified ORF, "Probable Hsp40p co-chaperone, has a DnaJ-like domain and appears to be involved in ER-associated degradation of misfolded proteins containing a tightly folded cytoplasmic domain; inhibits replication of Brome mosaic virus in S. cerevisiae" |
| 5726 | YPR062W | FCY1 SGDID:S000006266, Chr XVI from 677162-677638, Verified ORF, "Cytosine deaminase, zinc metalloenzyme that catalyzes the hydrolytic deamination of cytosine to uracil; of biomedical interest because it also catalyzes the deamination of 5-fluorocytosine (5FC) to form anticancer drug 5-fluorouracil (5FU)" |
| 5727 | YPR063C | YPR063C SGDID:S000006267, Chr XVI from 678317-678277,678190-677809, reverse complement, Uncharacterized ORF, "ER-localized protein of unknown function" |
| 5728 | YPR065W | ROX1 SGDID:S000006269, Chr XVI from 679690-680796, Verified ORF, "Heme-dependent repressor of hypoxic genes; contains an HMG domain that is responsible for DNA bending activity" |
| 5729 | YPR066W | UBA3 SGDID:S000006270, Chr XVI from 681210-682109, Verified ORF, "Protein that acts together with Ula1p to activate Rub1p before its conjugation to proteins (neddylation), which may play a role in protein degradation; GFP-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 5730 | YPR067W | ISA2 SGDID:S000006271, Chr XVI from 682217-682774, Verified ORF, "Protein required for maturation of mitochondrial and cytosolic Fe/S proteins, localizes to the mitochondrial intermembrane space, overexpression of ISA2 suppresses grx5 mutations" |
| 5731 | YPR068C | HOS1 SGDID:S000006272, Chr XVI from 684350-682938, reverse complement, Verified ORF, "Putative class I histone deacetylase (HDAC) with sequence similarity to Hda1p, Rpd3p, Hos2p, and Hos3p; deletion results in increased histone acetylation at rDNA repeats; interacts with the Tup1p-Ssn6p corepressor complex" |
| 5732 | YPR069C | SPE3 SGDID:S000006273, Chr XVI from 685434-684553, reverse complement, Verified ORF, "Spermidine synthase, involved in biosynthesis of spermidine and also in biosynthesis of pantothenic acid; spermidine is required for growth of wild-type cells" |
| 5733 | YPR070W | MED1 SGDID:S000006274, Chr XVI from 685895-687595, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; essential for transcriptional regulation" |
| 5734 | YPR071W | YPR071W SGDID:S000006275, Chr XVI from 688169-688804, Uncharacterized ORF, "Putative membrane protein; YPR071W is not an essential gene" |
| 5735 | YPR072W | NOT5 SGDID:S000006276, Chr XVI from 690104-691786, Verified ORF, "Subunit of the CCR4-NOT complex, which is a global transcriptional regulator with roles in transcription initiation and elongation and in mRNA degradation" |
| 5736 | YPR073C | LTP1 SGDID:S000006277, Chr XVI from 692415-691930, reverse complement, Verified ORF, "Protein phosphotyrosine phosphatase of unknown cellular role; activated by adenine" |
| 5737 | YPR074C | TKL1 SGDID:S000006278, Chr XVI from 694835-692793, reverse complement, Verified ORF, "Transketolase, similar to Tkl2p; catalyzes conversion of xylulose-5-phosphate and ribose-5-phosphate to sedoheptulose-7-phosphate and glyceraldehyde-3-phosphate in the pentose phosphate pathway; needed for synthesis of aromatic amino acids" |
| 5738 | YPR075C | OPY2 SGDID:S000006279, Chr XVI from 696816-695734, reverse complement, Verified ORF, "Integral membrane protein that functions in the signaling branch of the high-osmolarity glycerol (HOG) pathway; interacts with Ste50p; overproduction blocks cell cycle arrest in the presence of mating pheromone" |
| 5739 | YPR078C | YPR078C SGDID:S000006282, Chr XVI from 698262-697144, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; possible role in DNA metabolism and/or in genome stability; expression is heat-inducible" |
| 5740 | YPR079W | MRL1 SGDID:S000006283, Chr XVI from 698867-700012, Verified ORF, "Membrane protein with similarity to mammalian mannose-6-phosphate receptors, possibly functions as a sorting receptor in the delivery of vacuolar hydrolases" |
| 5741 | YPR080W | TEF1 SGDID:S000006284, Chr XVI from 700592-701968, Verified ORF, "Translational elongation factor EF-1 alpha; also encoded by TEF2; functions in the binding reaction of aminoacyl-tRNA (AA-tRNA) to ribosomes" |
| 5742 | YPR081C | GRS2 SGDID:S000006285, Chr XVI from 703968-702112, reverse complement, Verified ORF, "Protein with sequence similarity to Grs1p, which is a glycyl-tRNA synthetase; cannot substitute for Grs1p; possible pseudogene that is expressed at very low levels" |
| 5743 | YPR082C | DIB1 SGDID:S000006286, Chr XVI from 704654-704223, reverse complement, Verified ORF, "17-kDa component of the U4/U6aU5 tri-snRNP, plays an essential role in pre-mRNA splicing, orthologue of hDIM1, the human U5-specific 15-kDa protein" |
| 5744 | YPR083W | MDM36 SGDID:S000006287, Chr XVI from 704852-706591, Verified ORF, "Protein required for normal mitochondrial morphology and inheritance" |
| 5745 | YPR084W | YPR084W SGDID:S000006288, Chr XVI from 706970-708340, Uncharacterized ORF, "Putative protein of unknown function" |
| 5746 | YPR085C | YPR085C SGDID:S000006289, Chr XVI from 709826-708495, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; YPR085C is an essential gene" |
| 5747 | YPR086W | SUA7 SGDID:S000006290, Chr XVI from 710099-711136, Verified ORF, "Transcription factor TFIIB, a general transcription factor required for transcription initiation and start site selection by RNA polymerase II" |
| 5748 | YPR088C | SRP54 SGDID:S000006292, Chr XVI from 713026-711401, reverse complement, Verified ORF, "Signal recognition particle (SRP) subunit (homolog of mammalian SRP54); contains the signal sequence-binding activity of SRP, interacts with the SRP RNA, and mediates binding of SRP to signal receptor; contains GTPase domain" |
| 5749 | YPR089W | YPR089W SGDID:S000006293, Chr XVI from 713273-715939, Uncharacterized ORF, "Protein of unknown function; exhibits genetic interaction with ERG11 and protein-protein interaction with Hsp82p" |
| 5750 | YPR091C | YPR091C SGDID:S000006295, Chr XVI from 718466-716154, reverse complement, Verified ORF, "Putative protein of unknown function; may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the endoplasmic reticulum; YPR091C is not an essential gene" |
| 5751 | YPR093C | ASR1 SGDID:S000006297, Chr XVI from 720422-719556, reverse complement, Verified ORF, "Protein involved in a putative alcohol-responsive signaling pathway; accumulates in the nucleus under alcohol stress; contains a Ring/PHD finger domain" |
| 5752 | YPR094W | RDS3 SGDID:S000006298, Chr XVI from 720635-720958, Verified ORF, "Zinc cluster protein involved in pre-mRNA splicing and cycloheximide resistance" |
| 5753 | YPR095C | SYT1 SGDID:S000006299, Chr XVI from 724715-721035, reverse complement, Verified ORF, "Guanine nucleotide exchange factor (GEF) for Arf proteins; involved in vesicular transport; suppressor of ypt3 mutations; member of the Sec7-domain family" |
| 5754 | YPR096C | YPR096C SGDID:S000006300, Chr XVI from 725142-724840, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments" |
| 5755 | YPR097W | YPR097W SGDID:S000006301, Chr XVI from 725392-728613, Verified ORF, "Protein that contains a Phox homology (PX) domain and binds phosphoinositides; the authentic, non-tagged protein is detected in highly purified mitochondria in high-throughput studies" |
| 5756 | YPR098C | YPR098C SGDID:S000006302, Chr XVI from 729526-729480,729383-728945, reverse complement, Verified ORF, "Protein of unknown function, localized to the mitochondrial outer membrane" |
| 5757 | YPR100W | MRPL51 SGDID:S000006304, Chr XVI from 729789-730211, Verified ORF, "Mitochondrial ribosomal protein of the large subunit" |
| 5758 | YPR101W | SNT309 SGDID:S000006305, Chr XVI from 730490-731017, Verified ORF, "Component of NineTeen complex (NTC) containing Prp19p involved in mRNA splicing, interacts physically and genetically with Prp19p" |
| 5759 | YPR102C | RPL11A SGDID:S000006306, Chr XVI from 731746-731222, reverse complement, Verified ORF, "Protein component of the large (60S) ribosomal subunit, nearly identical to Rpl11Bp; involved in ribosomal assembly; depletion causes degradation of proteins and RNA of the 60S subunit; has similarity to E. coli L5 and rat L11" |
| 5760 | YPR103W | PRE2 SGDID:S000006307, Chr XVI from 732347-733210, Verified ORF, "Beta 5 subunit of the 20S proteasome, responsible for the chymotryptic activity of the proteasome" |
| 5761 | YPR104C | FHL1 SGDID:S000006308, Chr XVI from 736431-733621, reverse complement, Verified ORF, "Transcriptional activator with similarity to DNA-binding domain of Drosophila forkhead but unable to bind DNA in vitro; required for rRNA processing; isolated as a suppressor of splicing factor prp4" |
| 5762 | YPR105C | COG4 SGDID:S000006309, Chr XVI from 739567-736982, reverse complement, Verified ORF, "Essential component of the conserved oligomeric Golgi complex (Cog1p through Cog8p), a cytosolic tethering complex that functions in protein trafficking to mediate fusion of transport vesicles to Golgi compartments" |
| 5763 | YPR106W | ISR1 SGDID:S000006310, Chr XVI from 740059-741390, Verified ORF, "Predicted protein kinase, overexpression causes sensitivity to staurosporine, which is a potent inhibitor of protein kinase C" |
| 5764 | YPR107C | YTH1 SGDID:S000006311, Chr XVI from 742062-741436, reverse complement, Verified ORF, "Essential RNA-binding component of cleavage and polyadenylation factor, contains five zinc fingers; required for pre-mRNA 3'-end processing and polyadenylation" |
| 5765 | YPR108W | RPN7 SGDID:S000006312, Chr XVI from 742452-743741, Verified ORF, "Essential, non-ATPase regulatory subunit of the 26S proteasome, similar to another S. cerevisiae regulatory subunit, Rpn5p, as well as to mammalian proteasome subunits" |
| 5766 | YPR108W-A | YPR108W-A SGDID:S000028590, Chr XVI from 744173-744385, Uncharacterized ORF, "Putative protein of unknown function; identified by fungal homology and RT-PCR" |
| 5767 | YPR109W | YPR109W SGDID:S000006313, Chr XVI from 744687-745571, Uncharacterized ORF, "Predicted membrane protein; dipoid deletion strain has high budding index" |
| 5768 | YPR110C | RPC40 SGDID:S000006314, Chr XVI from 746833-745826, reverse complement, Verified ORF, "RNA polymerase subunit, common to RNA polymerase I and III" |
| 5769 | YPR111W | DBF20 SGDID:S000006315, Chr XVI from 747304-748998, Verified ORF, "Ser/Thr kinase involved in late nuclear division, one of the mitotic exit network (MEN) proteins; necessary for the execution of cytokinesis" |
| 5770 | YPR112C | MRD1 SGDID:S000006316, Chr XVI from 751917-749254, reverse complement, Verified ORF, "Essential conserved protein that is part of the 90S preribosome; required for production of 18S rRNA and small ribosomal subunit; contains five consensus RNA-binding domains" |
| 5771 | YPR113W | PIS1 SGDID:S000006317, Chr XVI from 752255-752917, Verified ORF, "Phosphatidylinositol synthase, required for biosynthesis of phosphatidylinositol, which is a precursor for polyphosphoinositides, sphingolipids, and glycolipid anchors for some of the plasma membrane proteins" |
| 5772 | YPR114W | YPR114W SGDID:S000006318, Chr XVI from 753299-754246, Uncharacterized ORF, "Putative protein of unknown function" |
| 5773 | YPR115W | YPR115W SGDID:S000006319, Chr XVI from 754875-758126, Uncharacterized ORF, "Pleckstrin homology domain containing protein proposed to function as a glycerol channel activator; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm" |
| 5774 | YPR116W | YPR116W SGDID:S000006320, Chr XVI from 758646-759479, Uncharacterized ORF, "Putative protein of unknown function" |
| 5775 | YPR117W | YPR117W SGDID:S000006321, Chr XVI from 760023-767492, Uncharacterized ORF, "Putative protein of unknown function" |
| 5776 | YPR118W | YPR118W SGDID:S000006322, Chr XVI from 767750-768985, Verified ORF, "Methylthioribose-1-phosphate isomerase, catalyzes the isomerization of 5-methylthioribose-1-phosphate to 5-methylthioribulose-1-phosphate in the methionine salvage pathway" |
| 5777 | YPR119W | CLB2 SGDID:S000006323, Chr XVI from 771651-773126, Verified ORF, "B-type cyclin involved in cell cycle progression; activates Cdc28p to promote the transition from G2 to M phase; accumulates during G2 and M, then targeted via a destruction box motif for ubiquitin-mediated degradation by the proteasome" |
| 5778 | YPR120C | CLB5 SGDID:S000006324, Chr XVI from 775180-773873, reverse complement, Verified ORF, "B-type cyclin involved in DNA replication during S phase; activates Cdc28p to promote initiation of DNA synthesis; functions in formation of mitotic spindles along with Clb3p and Clb4p; most abundant during late G1 phase" |
| 5779 | YPR121W | THI22 SGDID:S000006325, Chr XVI from 778579-780297, Verified ORF, "Protein with similarity to hydroxymethylpyrimidine phosphate kinases; member of a gene family with THI20 and THI21; not required for thiamine biosynthesis" |
| 5780 | YPR122W | AXL1 SGDID:S000006326, Chr XVI from 782041-785667, Verified ORF, "Haploid specific endoprotease that performs one of two N-terminal cleavages during maturation of a-factor mating pheromone; required for axial budding pattern of haploid cells" |
| 5781 | YPR124W | CTR1 SGDID:S000006328, Chr XVI from 786204-787424, Verified ORF, "High-affinity copper transporter of the plasma membrane, mediates nearly all copper uptake under low copper conditions; transcriptionally induced at low copper levels and degraded at high copper levels" |
| 5782 | YPR125W | YLH47 SGDID:S000006329, Chr XVI from 787957-789321, Verified ORF, "Mitochondrial inner membrane protein exposed to the mitochondrial matrix, associates with mitochondrial ribosomes, NOT required for respiratory growth; homolog of human Letm1, a protein implicated in Wolf-Hirschhorn syndrome" |
| 5783 | YPR127W | YPR127W SGDID:S000006331, Chr XVI from 790079-791116, Uncharacterized ORF, "Putative protein of unknown function; expression is activated by transcription factor YRM1/YOR172W; green fluorescent protein (GFP)-fusion protein localizes to both the cytoplasm and the nucleus" |
| 5784 | YPR128C | ANT1 SGDID:S000006332, Chr XVI from 792200-791214, reverse complement, Verified ORF, "Peroxisomal adenine nucleotide transporter; involved in beta-oxidation of medium-chain fatty acid; required for peroxisome proliferation" |
| 5785 | YPR129W | SCD6 SGDID:S000006333, Chr XVI from 792683-793732, Verified ORF, "Protein containing an Lsm domain, may bind RNA and have a role in RNA processing; overproduction suppresses a null mutation in CHC1, which encodes the heavy chain of clathrin" |
| 5786 | YPR131C | NAT3 SGDID:S000006335, Chr XVI from 794494-793907, reverse complement, Verified ORF, "Catalytic subunit of the NatB N-terminal acetyltransferase, which catalyzes acetylation of the amino-terminal methionine residues of all proteins beginning with Met-Asp or Met-Glu and of some proteins beginning with Met-Asn or Met-Met" |
| 5787 | YPR132W | RPS23B SGDID:S000006336, Chr XVI from 794961-795025,795391-795763, Verified ORF, "Ribosomal protein 28 (rp28) of the small (40S) ribosomal subunit, required for translational accuracy; nearly identical to Rps23Ap and similar to E. coli S12 and rat S23 ribosomal proteins; deletion of both RPS23A and RPS23B is lethal" |
| 5788 | YPR133C | SPN1 SGDID:S000006337, Chr XVI from 797206-795974, reverse complement, Verified ORF, "Protein that interacts with Spt6p and copurifies with Spt5p and RNA polymerase II, probable transcriptional elongation factor; metazoan homologs contain an acidic N terminus; mutations in the gene confer an Spt- phenotype" |
| 5789 | YPR133W-A | TOM5 SGDID:S000006433, Chr XVI from 797553-797705, Verified ORF, "Small mitochondrial outer membrane protein crucial to a binding relay for the import of proteins into mitochondria; subunit on the outer mouth of the TOM channel that accepts precursors from the receptors Tom20p and Tom22p" |
| 5790 | YPR134W | MSS18 SGDID:S000006338, Chr XVI from 798047-798853, Verified ORF, "Nuclear encoded protein needed for efficient splicing of mitochondrial COX1 aI5beta intron; mss18 mutations block cleavage of 5' exon - intron junction; phenotype of intronless strain suggests additional functions" |
| 5791 | YPR135W | CTF4 SGDID:S000006339, Chr XVI from 799230-802013, Verified ORF, "Chromatin-associated protein, required for sister chromatid cohesion; interacts with DNA polymerase alpha (Pol1p) and may link DNA synthesis to sister chromatid cohesion" |
| 5792 | YPR137C-A | YPR137C-A SGDID:S000007359, Chr XVI from 810265-808943, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 5793 | YPR137C-B | YPR137C-B SGDID:S000007360, Chr XVI from 810265-808961,808959-804997, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 5794 | YPR137W | RRP9 SGDID:S000006341, Chr XVI from 802355-804076, Verified ORF, "Protein involved in pre-rRNA processing, associated with U3 snRNP; component of small ribosomal subunit (SSU) processosome; ortholog of the human U3-55k protein" |
| 5795 | YPR138C | MEP3 SGDID:S000006342, Chr XVI from 812449-810980, reverse complement, Verified ORF, "Ammonium permease of high capacity and low affinity; belongs to a ubiquitous family of cytoplasmic membrane proteins that transport only ammonium (NH4+); expression is under the nitrogen catabolite repression regulation ammonia permease" |
| 5796 | YPR139C | VPS66 SGDID:S000006343, Chr XVI from 814054-813152, reverse complement, Verified ORF, "Cytoplasmic protein of unknown function involved in vacuolar protein sorting." |
| 5797 | YPR140W | TAZ1 SGDID:S000006344, Chr XVI from 814387-815532, Verified ORF, "Lyso-phosphatidylcholine acyltransferase, required for normal phospholipid content of mitochondrial membranes; may remodel acyl groups of cardiolipin in the inner membrane; similar to human tafazzin, which is implicated in Barth syndrome" |
| 5798 | YPR141C | KAR3 SGDID:S000006345, Chr XVI from 817919-815730, reverse complement, Verified ORF, "Minus-end-directed microtubule motor that functions in mitosis and meiosis, localizes to the spindle pole body and localization is dependent on functional Cik1p, required for nuclear fusion during mating; potential Cdc28p substrate" |
| 5799 | YPR143W | RRP15 SGDID:S000006347, Chr XVI from 818319-819071, Verified ORF, "Nucleolar protein, constituent of pre-60S ribosomal particles; required for proper processing of the 27S pre-rRNA at the A3 and B1 sites to yield mature 5.8S and 25S rRNAs" |
| 5800 | YPR144C | NOC4 SGDID:S000006348, Chr XVI from 821419-819761, reverse complement, Verified ORF, "Nucleolar protein, forms a complex with Nop14p that mediates maturation and nuclear export of 40S ribosomal subunits" |
| 5801 | YPR145C-A | YPR145C-A SGDID:S000113589, Chr XVI from 824922-824686, reverse complement, Uncharacterized ORF, "Putative protein of unknown function" |
| 5802 | YPR145W | ASN1 SGDID:S000006349, Chr XVI from 822616-824334, Verified ORF, "Asparagine synthetase, isozyme of Asn2p; catalyzes the synthesis of L-asparagine from L-aspartate in the asparagine biosynthetic pathway" |
| 5803 | YPR147C | YPR147C SGDID:S000006351, Chr XVI from 826555-825641, reverse complement, Uncharacterized ORF, "Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm and is induced in response to the DNA-damaging agent MMS" |
| 5804 | YPR148C | YPR148C SGDID:S000006352, Chr XVI from 828136-826829, reverse complement, Verified ORF, "Protein of unknown function that may interact with ribosomes, based on co-purification experiments; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm in a punctate pattern" |
| 5805 | YPR149W | NCE102 SGDID:S000006353, Chr XVI from 829914-830435, Verified ORF, "Protein of unknown function; contains transmembrane domains; involved in secretion of proteins that lack classical secretory signal sequences; component of the detergent-insoluble glycolipid-enriched complexes (DIGs)" |
| 5806 | YPR151C | SUE1 SGDID:S000006355, Chr XVI from 831671-831051, reverse complement, Verified ORF, "Mitochondrial protein required for degradation of unstable forms of cytochrome c" |
| 5807 | YPR152C | YPR152C SGDID:S000006356, Chr XVI from 833454-832057, reverse complement, Uncharacterized ORF, "Pre-mRNA splicing factor associated with the U2-U5-U6 snRNPs, the RES complex, and the Prp19-associated complex (NTC); null mutation displays synthetic genetic interactions with mutations affecting U2 snRNA and pre-mRNA splicing factors" |
| 5808 | YPR153W | YPR153W SGDID:S000006357, Chr XVI from 833685-833689,833824-834241, Verified ORF, "Putative protein of unknown function" |
| 5809 | YPR154W | PIN3 SGDID:S000006358, Chr XVI from 834561-835208, Verified ORF, "Protein that induces appearance of [PIN+] prion when overproduced" |
| 5810 | YPR155C | NCA2 SGDID:S000006359, Chr XVI from 837409-835559, reverse complement, Verified ORF, "Protein involved in regulation of mitochondrial expression of subunits 6 (Atp6p) and 8 (Atp8p) of the Fo-F1 ATP synthase; functions with Nca3p" |
| 5811 | YPR156C | TPO3 SGDID:S000006360, Chr XVI from 839773-837905, reverse complement, Verified ORF, "Polyamine transport protein specific for spermine; localizes to the plasma membrane; member of the major facilitator superfamily" |
| 5812 | YPR157W | YPR157W SGDID:S000006361, Chr XVI from 841262-842665, Uncharacterized ORF, "Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation" |
| 5813 | YPR158C-C | YPR158C-C SGDID:S000007361, Chr XVI from 856253-854931, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 5814 | YPR158C-D | YPR158C-D SGDID:S000007362, Chr XVI from 856253-854949,854947-850985, reverse complement, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 5815 | YPR158W | YPR158W SGDID:S000006362, Chr XVI from 843258-844016, Uncharacterized ORF, "Putative protein of unknown function" |
| 5816 | YPR158W-A | YPR158W-A SGDID:S000007363, Chr XVI from 844705-846027, transposable_element_gene, "Retrotransposon TYA Gag gene co-transcribed with TYB Pol; translated as TYA or TYA-TYB polyprotein; Gag is a nucleocapsid protein that is the structural constituent of virus-like particles (VLPs); similar to retroviral Gag" |
| 5817 | YPR158W-B | YPR158W-B SGDID:S000007364, Chr XVI from 844705-846009,846011-849976, transposable_element_gene, "Retrotransposon TYA Gag and TYB Pol genes; transcribed/translated as one unit; polyprotein is processed to make a nucleocapsid-like protein (Gag), reverse transcriptase (RT), protease (PR), and integrase (IN); similar to retroviral genes" |
| 5818 | YPR159C-A | YPR159C-A SGDID:S000028725, Chr XVI from 860411-860310, reverse complement, Uncharacterized ORF, "Identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching" |
| 5819 | YPR159W | KRE6 SGDID:S000006363, Chr XVI from 857579-859741, Verified ORF, "Protein required for beta-1,6 glucan biosynthesis; putative beta-glucan synthase; appears functionally redundant with Skn1p" |
| 5820 | YPR160W | GPH1 SGDID:S000006364, Chr XVI from 861302-864010, Verified ORF, "Non-essential glycogen phosphorylase required for the mobilization of glycogen, activity is regulated by cyclic AMP-mediated phosphorylation, expression is regulated by stress-response elements and by the HOG MAP kinase pathway" |
| 5821 | YPR161C | SGV1 SGDID:S000006365, Chr XVI from 866418-864445, reverse complement, Verified ORF, "Cyclin (Bur2p)-dependent protein kinase that functions in transcriptional regulation; phosphorylates the carboxy-terminal domain of Rpo21p, which is the largest subunit of RNA polymerase II; regulated by Cak1p" |
| 5822 | YPR162C | ORC4 SGDID:S000006366, Chr XVI from 868300-866711, reverse complement, Verified ORF, "Subunit of the origin recognition complex, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing" |
| 5823 | YPR163C | TIF3 SGDID:S000006367, Chr XVI from 869951-868641, reverse complement, Verified ORF, "Translation initiation factor eIF-4B, has RNA annealing activity; contains an RNA recognition motif and binds to single-stranded RNA" |
| 5824 | YPR164W | MMS1 SGDID:S000006368, Chr XVI from 870699-874922, Verified ORF, "Protein likely involved in protection against replication-dependent DNA damage; mutants are sensitive to methyl methanesulfonate (MMS); implicated in regulation of Ty1 transposition" |
| 5825 | YPR165W | RHO1 SGDID:S000006369, Chr XVI from 875364-875993, Verified ORF, "GTP-binding protein of the rho subfamily of Ras-like proteins, involved in establishment of cell polarity; regulates protein kinase C (Pkc1p) and the cell wall synthesizing enzyme 1,3-beta-glucan synthase (Fks1p and Gsc2p)" |
| 5826 | YPR166C | MRP2 SGDID:S000006370, Chr XVI from 876625-876278, reverse complement, Verified ORF, "Mitochondrial ribosomal protein of the small subunit" |
| 5827 | YPR167C | MET16 SGDID:S000006371, Chr XVI from 877628-876843, reverse complement, Verified ORF, "3'-phosphoadenylsulfate reductase, reduces 3'-phosphoadenylyl sulfate to adenosine-3',5'-bisphosphate and free sulfite using reduced thioredoxin as cosubstrate, involved in sulfate assimilation and methionine metabolism" |
| 5828 | YPR168W | NUT2 SGDID:S000006372, Chr XVI from 878072-878545, Verified ORF, "Subunit of the RNA polymerase II mediator complex; associates with core polymerase subunits to form the RNA polymerase II holoenzyme; required for transcriptional activation and has a role in basal transcription" |
| 5829 | YPR169W | JIP5 SGDID:S000006373, Chr XVI from 878686-880164, Uncharacterized ORF, "Nucleolar protein of unknown function, exhibits a physical interaction with Bre1p" |
| 5830 | YPR170W-B | YPR170W-B SGDID:S000028515, Chr XVI from 883235-883383,883483-883591, Uncharacterized ORF, "Putative protein of unknown function, conserved in fungi; partially overlaps the dubious genes YPR169W-A, YPR170W-A and YRP170C" |
| 5831 | YPR171W | BSP1 SGDID:S000006375, Chr XVI from 883824-885554, Verified ORF, "Adapter that links synaptojanins Inp52p and Inp53p to the cortical actin cytoskeleton" |
| 5832 | YPR172W | YPR172W SGDID:S000006376, Chr XVI from 885792-886394, Uncharacterized ORF, "Protein of unknown function, transcriptionally activated by Yrm1p along with genes involved in multidrug resistance" |
| 5833 | YPR173C | VPS4 SGDID:S000006377, Chr XVI from 887833-886520, reverse complement, Verified ORF, "AAA-type ATPase that is regulated by Vta1p; required for late endosome to vacuole transport; catalyzes the release of an endosomal membrane-associated class E VPS protein complex; regulates cellular sterol metabolism" |
| 5834 | YPR174C | YPR174C SGDID:S000006378, Chr XVI from 888704-888039, reverse complement, Uncharacterized ORF, "Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nuclear periphery; potential Cdc28p substrate" |
| 5835 | YPR175W | DPB2 SGDID:S000006379, Chr XVI from 888970-891039, Verified ORF, "Second largest subunit of DNA polymerase II (DNA polymerase epsilon), required for normal yeast chromosomal replication; expression peaks at the G1/S phase boundary; potential Cdc28p substrate" |
| 5836 | YPR176C | BET2 SGDID:S000006380, Chr XVI from 892074-891097, reverse complement, Verified ORF, "Beta subunit of Type II geranylgeranyltransferase required for vesicular transport between the endoplasmic reticulum and the Golgi; provides a membrane attachment moiety to Rab-like proteins Ypt1p and Sec4p" |
| 5837 | YPR178W | PRP4 SGDID:S000006382, Chr XVI from 892328-893725, Verified ORF, "Splicing factor, component of the U4/U6-U5 snRNP complex" |
| 5838 | YPR179C | HDA3 SGDID:S000006383, Chr XVI from 895760-893793, reverse complement, Verified ORF, "Subunit of a possibly tetrameric trichostatin A-sensitive class II histone deacetylase complex that contains an Hda1p homodimer and an Hda2p-Hda3p heterodimer; required for the activity of the complex; has similarity to Hda2p" |
| 5839 | YPR180W | AOS1 SGDID:S000006384, Chr XVI from 895957-897000, Verified ORF, "Nuclear protein that acts as a heterodimer with Uba2p to activate Smt3p (SUMO) before its conjugation to proteins (sumoylation), which may play a role in protein targeting; essential for viability" |
| 5840 | YPR181C | SEC23 SGDID:S000006385, Chr XVI from 899663-897357, reverse complement, Verified ORF, "GTPase-activating protein; component of the Sec23p-Sec24p heterodimeric complex of the COPII vesicle coat, involved in ER to Golgi transport and autophagy; stimulates the GDP-bound form of Sar1p" |
| 5841 | YPR182W | SMX3 SGDID:S000006386, Chr XVI from 900190-900450, Verified ORF, "Core Sm protein Sm F; part of heteroheptameric complex (with Smb1p, Smd1p, Smd2p, Smd3p, Sme1p, and Smx2p) that is part of the spliceosomal U1, U2, U4, and U5 snRNPs; homolog of human Sm F" |
| 5842 | YPR183W | DPM1 SGDID:S000006387, Chr XVI from 900751-901554, Verified ORF, "Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane, catalyzes the formation of Dol-P-Man from Dol-P and GDP-Man; required for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and protein glycosylation" |
| 5843 | YPR184W | GDB1 SGDID:S000006388, Chr XVI from 902040-906650, Verified ORF, "Glycogen debranching enzyme containing glucanotranferase and alpha-1,6-amyloglucosidase activities, required for glycogen degradation; phosphorylated in mitochondria" |
| 5844 | YPR185W | ATG13 SGDID:S000006389, Chr XVI from 907214-909430, Verified ORF, "Regulatory subunit of the Atg1p signaling complex; stimulates Atg1p kinase activity; required for vesicle formation during autophagy and the cytoplasm-to-vacuole targeting (Cvt) pathway; involved in Atg9p, Atg23p, and Atg27p cycling" |
| 5845 | YPR186C | PZF1 SGDID:S000006390, Chr XVI from 911018-909729, reverse complement, Verified ORF, "Transcription factor IIIA (TFIIIA), essential protein with nine C2H2 Zn-fingers, binds the 5S rRNA gene through the zinc finger domain and directs assembly of a multiprotein initiation complex for RNA polymerase III; also binds DNA" |
| 5846 | YPR187W | RPO26 SGDID:S000006391, Chr XVI from 911253-911272,911349-911796, Verified ORF, "RNA polymerase subunit ABC23, common to RNA polymerases I, II, and III; part of central core; similar to bacterial omega subunit" |
| 5847 | YPR188C | MLC2 SGDID:S000006392, Chr XVI from 912475-911984, reverse complement, Verified ORF, "Regulatory light chain for the type II myosin, Myo1p; binds to an IQ motif of Myo1p, localization to the bud neck depends on Myo1p; involved in the disassembly of the Myo1p ring" |
| 5848 | YPR189W | SKI3 SGDID:S000006393, Chr XVI from 912660-916958, Verified ORF, "Protein involved in exosome mediated 3' to 5' mRNA degradation and translation inhibition of non-poly(A) mRNAs; forms complex with Ski2p and Ski8p; required for repressing propagation of dsRNA viruses" |
| 5849 | YPR190C | RPC82 SGDID:S000006394, Chr XVI from 919037-917073, reverse complement, Verified ORF, "RNA polymerase III subunit C82" |
| 5850 | YPR191W | QCR2 SGDID:S000006395, Chr XVI from 919377-920483, Verified ORF, "Subunit 2 of the ubiquinol cytochrome-c reductase complex, which is a component of the mitochondrial inner membrane electron transport chain; phosphorylated; transcription is regulated by Hap1p, Hap2p/Hap3p, and heme" |
| 5851 | YPR192W | AQY1 SGDID:S000006396, Chr XVI from 921856-922773, Verified ORF, "Spore-specific water channel that mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance" |
| 5852 | YPR193C | HPA2 SGDID:S000006397, Chr XVI from 923375-922905, reverse complement, Verified ORF, "Tetrameric histone acetyltransferase with similarity to Gcn5p, Hat1p, Elp3p, and Hpa3p; acetylates histones H3 and H4 in vitro and exhibits autoacetylation activity" |
| 5853 | YPR194C | OPT2 SGDID:S000006398, Chr XVI from 926933-924300, reverse complement, Verified ORF, "Oligopeptide transporter; member of the OPT family, with potential orthologs in S. pombe and C. albicans" |
| 5854 | YPR196W | YPR196W SGDID:S000006400, Chr XVI from 931372-932784, Uncharacterized ORF, "Putative maltose activator" |
| 5855 | YPR198W | SGE1 SGDID:S000006402, Chr XVI from 934030-935661, Verified ORF, "Plasma membrane multidrug transporter of the major facilitator superfamily, acts as an extrusion permease; partial multicopy suppressor of gal11 mutations" |
| 5856 | YPR199C | ARR1 SGDID:S000006403, Chr XVI from 939028-938144, reverse complement, Verified ORF, "Transcriptional activator of the bZIP family, required for transcription of genes involved in resistance to arsenic compounds" |
| 5857 | YPR200C | ARR2 SGDID:S000006404, Chr XVI from 939667-939275, reverse complement, Verified ORF, "Arsenate reductase required for arsenate resistance; converts arsenate to arsenite which can then be exported from cells by Arr3p" |
| 5858 | YPR201W | ARR3 SGDID:S000006405, Chr XVI from 939918-941132, Verified ORF, "Arsenite transporter of the plasma membrane, required for resistance to arsenic compounds; transcription is activated by Arr1p in the presence of arsenite" |
| 5859 | YPR202W | YPR202W SGDID:S000006406, Chr XVI from 943028-943046,943195-943892, Uncharacterized ORF, "Putative protein of unknown function with similarity to telomere-encoded helicases; YPR202W is not an essential gene; transcript is predicted to be spliced but there is no evidence that it is spliced in vivo" |
| 5860 | YPR203W | YPR203W SGDID:S000006407, Chr XVI from 943876-944184, Uncharacterized ORF, "Putative protein of unknown function" |
| 5861 | YPR204W | YPR204W SGDID:S000006408, Chr XVI from 944599-947697, Uncharacterized ORF, "Helicase-like protein encoded within the telomeric Y' element" |
| 5862 | Q0045 | COX1 SGDID:S000007260, Chr Mito from 13818-13986,16435-16470,18954-18991,20508-20984,21995-22246,23612-23746,25318-25342,26229-26701, Verified ORF, "Subunit I of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits" |
| 5863 | Q0050 | AI1 SGDID:S000007261, Chr Mito from 13818-16322, Verified ORF, "Reverse transcriptase required for splicing of the COX1 pre-mRNA, encoded by a mobile group II intron within the mitochondrial COX1 gene" |
| 5864 | Q0055 | AI2 SGDID:S000007262, Chr Mito from 13818-13986,16435-18830, Verified ORF, "Reverse transcriptase required for splicing of the COX1 pre-mRNA, encoded by a mobile group II intron within the mitochondrial COX1 gene" |
| 5865 | Q0060 | AI3 SGDID:S000007263, Chr Mito from 13818-13986,16435-16470,18954-19996, Verified ORF, "Endonuclease I-SceIII, encoded by a mobile group I intron within the mitochondrial COX1 gene" |
| 5866 | Q0065 | AI4 SGDID:S000007264, Chr Mito from 13818-13986,16435-16470,18954-18991,20508-21935, Verified ORF, "Endonuclease I-SceII, encoded by a mobile group I intron within the mitochondrial COX1 gene; intron is normally spliced by the BI4p maturase but AI4p can mutate to acquire the same maturase activity" |
| 5867 | Q0070 | AI5_ALPHA SGDID:S000007265, Chr Mito from 13818-13986,16435-16470,18954-18991,20508-20984,21995-23167, Verified ORF, "Endonuclease I-SceIV, involved in intron mobility; encoded by a mobile group I intron within the mitochondrial COX1 gene" |
| 5868 | Q0075 | AI5_BETA SGDID:S000007266, Chr Mito from 24156-24870,24906-25255, Uncharacterized ORF, "Protein of unknown function, encoded within an intron of the mitochondrial COX1 gene; translational initiation codon is predicted to be ATA rather than ATG" |
| 5869 | Q0080 | ATP8 SGDID:S000007267, Chr Mito from 27666-27812, Verified ORF, "Subunit 8 of the F0 sector of mitochondrial inner membrane F1-F0 ATP synthase, encoded on the mitochondrial genome" |
| 5870 | Q0085 | ATP6 SGDID:S000007268, Chr Mito from 28487-29266, Verified ORF, "Mitochondrially encoded subunit 6 of the F0 sector of mitochondrial F1F0 ATP synthase, which is a large, evolutionarily conserved enzyme complex required for ATP synthesis" |
| 5871 | Q0105 | COB SGDID:S000007270, Chr Mito from 36540-36954,37723-37736,39141-39217,40841-41090,42508-42558,43297-43647, Verified ORF, "Cytochrome b, mitochondrially encoded subunit of the ubiquinol-cytochrome c reductase complex which includes Cobp, Rip1p, Cyt1p, Cor1p, Qcr2p, Qcr6p, Qcr7p, Qcr8p, Qcr9p, and Qcr10p" |
| 5872 | Q0110 | BI2 SGDID:S000007271, Chr Mito from 36540-36954,37723-38579, Verified ORF, "Mitochondrial mRNA maturase with a role in splicing, encoded by both exon and intron sequences of partially processed COB mRNA" |
| 5873 | Q0115 | BI3 SGDID:S000007272, Chr Mito from 36540-36954,37723-37736,39141-40265, Verified ORF, "Mitochondrial mRNA maturase, forms a complex with Mrs1p to mediate splicing of the bI3 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA" |
| 5874 | Q0120 | BI4 SGDID:S000007273, Chr Mito from 36540-36954,37723-37736,39141-39217,40841-42251, Verified ORF, "Mitochondrial mRNA maturase, forms a complex with Nam2p to mediate splicing of the bI4 intron of the COB gene; encoded by both exon and intron sequences of partially processed COB mRNA" |
| 5875 | Q0130 | OLI1 SGDID:S000007274, Chr Mito from 46723-46953, Verified ORF, "F0-ATP synthase subunit 9 (ATPase-associated proteolipid), encoded on the mitochondrial genome; mutation confers oligomycin resistance; expression is specifically dependent on the nuclear genes AEP1 and AEP2" |
| 5876 | Q0140 | VAR1 SGDID:S000007275, Chr Mito from 48901-50097, Verified ORF, "Mitochondrial ribosomal protein of the small subunit, mitochondrially-encoded; polymorphic in different strains due to variation in number of AAT (asparagine) codons; translated near the mitochondrial inner membrane" |
| 5877 | Q0160 | SCEI SGDID:S000007279, Chr Mito from 61022-61729, Verified ORF, "I-SceI DNA endonuclease, encoded by the mitochondrial group I intron of the 21S_rRNA gene; mediates gene conversion that propagates the intron into intron-less copies of the 21S_rRNA gene" |
| 5878 | Q0250 | COX2 SGDID:S000007281, Chr Mito from 73758-74513, Verified ORF, "Subunit II of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits" |
| 5879 | Q0255 | Q0255 SGDID:S000007282, Chr Mito from 74495-75622,75663-75872,75904-75984, Uncharacterized ORF, "Maturase-like protein" |
| 5880 | Q0275 | COX3 SGDID:S000007283, Chr Mito from 79213-80022, Verified ORF, "Subunit III of cytochrome c oxidase, which is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits" |
| 5881 | R0010W | FLP1 SGDID:S000029654, 2-micron plasmid from 252-1523, Verified ORF, "Site-specific recombinase encoded on the 2-micron plasmid, required for 2-micron plasmid propagation as part of a plasmid amplification system that compensates for any copy number decreases caused by missegregation events" |
| 5882 | R0020C | REP1 SGDID:S000029675, 2-micron plasmid from 3008-1887, reverse complement, Verified ORF, "Master regulator that acts in concert with Rep2p to regulate transcript levels of the FLP1 gene that promotes plasmid copy amplification; autoregulates levels of its own transcript" |
| 5883 | R0030W | RAF1 SGDID:S000029674, 2-micron plasmid from 3271-3816, Verified ORF, "Anti-repressor that increases 2 micron plasmid copy number by relieving repression of the FLP1 site-specific recombinase caused by the Rep1-Rep2p trascription regulator; also itself repressed by the Rep1p-Rep2p complex" |
| 5884 | R0040C | REP2 SGDID:S000029676, 2-micron plasmid from 6198-5308, reverse complement, Verified ORF, "Master regulator that acts in concert with Rep1p to regulate transcript levels of the FLP1 gene that promotes plasmid copy amplification; also autoregulates levels of its own transcript" |