ProGlyProt IDBU170
Organism Information
Organism NameHelicobacter felis CS1
DomainBacteria
ClassificationFamily: Helicobacteraceae
Order: Campylobacterales
Class: Epsilonproteobacteria
Division or phylum: "Proteobacteria"
Taxonomic ID (NCBI)936155
Genome Sequence (s)
GeneBankFQ670179.2
EMBLFQ670179
Gene Information
Gene NameflaA (Hfelis_04060)
NCBI Gene ID10050848
Protein Information
Protein NameFlagellin A
UniProtKB/SwissProt IDQ9XB38
NCBI RefSeqYP_004073080.1
EMBL-CDSCBY82490.1
UniProtKB Sequence>sp|Q9XB38|FLAA_HELFC Flagellin A OS=Helicobacter felis (strain ATCC 49179 / NCTC 12436 / CS1) GN=flaA PE=3 SV=3
MAFQVNTNINALNAHAMGLVTQRELKESLERLSSGLRINKAADDASGMTIADSLRSQAKS LGQAIANTNDGMGIIQIADKAMDEQIKILDTIKVKATQAAQDGQNTQSRKALQADIVRLI QSLDNIGNTTSYNGQTLLSGAFSNKEFQVGAYSNETIKASIGSATSDKIGQVKITTGKNI TASGEVALTFKQVDGVHDVSLESVKISTSAGTGLGVLAEVINKNSNATGVRATANVITTS DSAIKSGSLSSLTVNGIEIGNILGIKKNDSDGRLVAALNAVTAQTGVEAYTDSVGRLNLR SIDGRGINIKANSTNVDGQASALTTLNGGQDITRGSTNFGRLSLVRQDARDILVVSGANV SASAGYAAIGFAKGTTANTTVNLRDVLGEFNQAVRSASGANYNKTLASENLTLGSGVTTL RGAMVVMDIAESAQKMLDKVRSDLGSVQNQMVSTVNNITITQVNVKAAESQIRDVDFAQE SANFSKNNILAQSGSYAMSQANTVQQNILRLLT
Sequence length513 AA
Subcellular LocationSecreted
FunctionFlaA and FlaB are co-assembled into one flagellar flament. H. felis flaA mutants possess truncated sheathed flagella and are unable to colonize murine stomach.
Glycosylation Status
Glycosylation TypeInformation currently not available with us.
Technique(s) used for Glycosylation DetectionDIG (digoxigenin)-tagged hydrazine labeling after periodate treatment.
Literatures
Reference(s)1) Josenhans, C., Ferrero, R.L., Labigne, A. and Suerbaum, S. (1999) Cloning and allelic exchange mutagenesis of two flagellin genes of Helicobacter felis. Mol Microbiol, 33, 350-362. [PubMed: 10411751]
Year of Identification1999