| ProGlyProt ID | BU164 |
| Organism Information |
| Organism Name | Escherichia coli (ETEC) strain H10407 |
| Domain | Bacteria |
| Classification | Family: Enterobacteriaceae
Order: "Enterobacteriales"
Class: Gammaproteobacteria
Division or phylum: "Proteobacteria" |
| Taxonomic ID (NCBI) | 316401 |
| Genome Sequence (s) |
| GeneBank | FN649414 |
| EMBL | FN649414 |
| Gene Information |
| Gene Name | tibA (ETEC_2141) |
| NCBI Gene ID | |
| Protein Information |
| Protein Name | TibA (outer membrane protein synthesized as preTib |
| UniProtKB/SwissProt ID | Q9XD84 |
| NCBI RefSeq | |
| EMBL-CDS | CBJ01643.1 |
| UniProtKB Sequence | >sp|Q9XD84|TIBA_ECOLX Adhesin/invasin TibA autotransporter OS=Escherichia coli GN=tibA PE=1 SV=1
MNKVYNTVWNESTGTWVVTSELTRKGGLRPRQIKRTVLAGLIAGLLMPSMPALAAAYDNQ
TIGRGETSKSMHLSAGDTAKNTTINSGGKQYVSSGGSATSTTINIGGVQHVSSGGSATSS
TINSGGHQHVSSGGSATNTTVNNGGRQTVFSGGSAMGTIINSGGDQYVISGGSATSASVT
SGARQFVSSGGIVKATSVNSGGRQYVRDGGSATDTVLNNTGRQFVSSGGSAAKTTINSGG
GMYLYGGSATGTSIYNGGRQYVSSGGSATNTTVYSGGRQHVYIDGNVTETTITSGGMLQV
EAGGSASKVIQNSGGAVITNTSAAVSGTNDNGSFSIAGGSAVNMLLENGGYLTVFDGHQA
SDTMVGSDGTLDVRSGGVLYGTTTLTDKGALVGDVVTNEGNLYYLNNSTATFTGTLTGTG
TLTQEGGNTRFSGLLSQDGGIFLQSGGAMTMDALQAKANVTTQSGTTLTLDNGTILTGNV
AGDSTGAGDMAVKGASVWHLDGDSTVGALTLDNGTVDFRPSTTTRMTPAFQAVSLALGSL
SGSGTFQMNTDIASHTGDMLNVAGNASGNFVLDIKNTGLEPVSAGAPLQVVQTGGGDAAF
TLKGGKVDAGTWEYGLSKENTNWYLKADTPPPVTPPTNPDADNPDAGNPDAGNPDAGNPD
AGNPDAGKPGTGKPDAGTSSSPVRRTTKSVDAVLGMATAPAYVFNSELDNLRFRHGDVMQ
NTRAPGGVWGRYTGSDNRISGGASSGYTLTQNGFETGADMVFDLSDSSLAVGTFFSYSDN
SIKHARGGKSNVDSSGGGLYATWFDNDGYYVDGVLKYNRFNNELRTWMSDGTAVKGDYSQ
NGFGGSLEAGRTFSLNENAWAQPYVRTTAFRADKKEIRLNNGMKASIGATKSLQAEAGLK
LGMTLDVAGKEVKPYLSAAVSHEFSDNNKVRINDTYDFRNDISGTTGKYGLGVNAQLTPN
AGVWAEARYENGKQTESPITGGVGFRINF |
| Sequence length | 989 AA |
| Subcellular Location | Secreted (surface associated) |
| Function | Adhesion-invasion protein of enterotoxigenic E. coli. Secreted as autotransporter, which represents a branch of the type V secretion pathway. Mediates bacterial autoaggregation and biofilm formation as well as adhesion to and invasion of mammalian cells. |
| Glycosylation Status |
| Glycosylation Type | Information currently not available with us. |
| Technique(s) used for Glycosylation Detection | Oxidation of the glycans with periodate and labeling with hydrazide-conjugated digoxigenin (DIG). |
| Literatures |
| Reference(s) | 1) Lindenthal, C. and Elsinghorst, E.A. (1999) Identification of a glycoprotein produced by enterotoxigenic Escherichia coli. Infect Immun, 67, 4084-4091. [PubMed: 10417177] |
| Year of Identification | 1999 |
