ProGlyProt ID BU164 Organism Information Organism Name Escherichia coli (ETEC) strain H10407 Domain Bacteria Classification Family: Enterobacteriaceae Order: "Enterobacteriales" Class: Gammaproteobacteria Division or phylum: "Proteobacteria" Taxonomic ID (NCBI) 316401 Genome Sequence (s) GeneBank FN649414 EMBL FN649414 Gene Information Gene Name tibA (ETEC_2141) NCBI Gene ID Protein Information Protein Name TibA (outer membrane protein synthesized as preTib UniProtKB/SwissProt ID Q9XD84 NCBI RefSeq EMBL-CDS CBJ01643.1 UniProtKB Sequence >sp|Q9XD84|TIBA_ECOLX Adhesin/invasin TibA autotransporter OS=Escherichia coli GN=tibA PE=1 SV=1 MNKVYNTVWNESTGTWVVTSELTRKGGLRPRQIKRTVLAGLIAGLLMPSMPALAAAYDNQ TIGRGETSKSMHLSAGDTAKNTTINSGGKQYVSSGGSATSTTINIGGVQHVSSGGSATSS TINSGGHQHVSSGGSATNTTVNNGGRQTVFSGGSAMGTIINSGGDQYVISGGSATSASVT SGARQFVSSGGIVKATSVNSGGRQYVRDGGSATDTVLNNTGRQFVSSGGSAAKTTINSGG GMYLYGGSATGTSIYNGGRQYVSSGGSATNTTVYSGGRQHVYIDGNVTETTITSGGMLQV EAGGSASKVIQNSGGAVITNTSAAVSGTNDNGSFSIAGGSAVNMLLENGGYLTVFDGHQA SDTMVGSDGTLDVRSGGVLYGTTTLTDKGALVGDVVTNEGNLYYLNNSTATFTGTLTGTG TLTQEGGNTRFSGLLSQDGGIFLQSGGAMTMDALQAKANVTTQSGTTLTLDNGTILTGNV AGDSTGAGDMAVKGASVWHLDGDSTVGALTLDNGTVDFRPSTTTRMTPAFQAVSLALGSL SGSGTFQMNTDIASHTGDMLNVAGNASGNFVLDIKNTGLEPVSAGAPLQVVQTGGGDAAF TLKGGKVDAGTWEYGLSKENTNWYLKADTPPPVTPPTNPDADNPDAGNPDAGNPDAGNPD AGNPDAGKPGTGKPDAGTSSSPVRRTTKSVDAVLGMATAPAYVFNSELDNLRFRHGDVMQ NTRAPGGVWGRYTGSDNRISGGASSGYTLTQNGFETGADMVFDLSDSSLAVGTFFSYSDN SIKHARGGKSNVDSSGGGLYATWFDNDGYYVDGVLKYNRFNNELRTWMSDGTAVKGDYSQ NGFGGSLEAGRTFSLNENAWAQPYVRTTAFRADKKEIRLNNGMKASIGATKSLQAEAGLK LGMTLDVAGKEVKPYLSAAVSHEFSDNNKVRINDTYDFRNDISGTTGKYGLGVNAQLTPN AGVWAEARYENGKQTESPITGGVGFRINF Sequence length 989 AA Subcellular Location Secreted (surface associated) Function Adhesion-invasion protein of enterotoxigenic E. coli. Secreted as autotransporter, which represents a branch of the type V secretion pathway. Mediates bacterial autoaggregation and biofilm formation as well as adhesion to and invasion of mammalian cells. Glycosylation Status Glycosylation Type Information currently not available with us. Technique(s) used for Glycosylation Detection Oxidation of the glycans with periodate and labeling with hydrazide-conjugated digoxigenin (DIG). Literatures Reference(s) 1) Lindenthal, C. and Elsinghorst, E.A. (1999) Identification of a glycoprotein produced by enterotoxigenic Escherichia coli. Infect Immun, 67, 4084-4091. [PubMed: 10417177] Year of Identification 1999