| ProGlyProt ID | BU103 |
| Organism Information |
| Organism Name | Actinobacillus actinomycetemcomitans Y4 (serotype |
| Domain | Bacteria |
| Classification | Family: Pasteurellaceae
Order: Pasteurellales
Class: Gammaproteobacteria
Division or phylum: "Proteobacteria" |
| Taxonomic ID (NCBI) | |
| Genome Sequence (s) |
| GeneBank | |
| EMBL | |
| Gene Information |
| Gene Name | |
| NCBI Gene ID | |
| Protein Information |
| Protein Name | 37-kDa protein |
| UniProtKB/SwissProt ID | |
| NCBI RefSeq | |
| EMBL-CDS | |
| UniProtKB Sequence | |
| Sequence length | |
| Subcellular Location | Extracellular |
| Function | Plays a role in A. actinomycetemcomitans-associated periodontitis, as antigen inducing the release of inflammatory cytokines which are associated with alveolar bone loss. The IL-6-inducing activity was higher than that of LPS. |
| Glycosylation Status |
| Glycosylation Type | Information currently not available with us. |
| Technique(s) used for Glycosylation Detection | Immunoblotting using anti glycan antibodies. |
| Literatures |
| Reference(s) | 1) Tani, Y., Tani, M. and Kato, I. (1997) Extracellular 37-kDa antigenic protein from Actinobacillus actinomycetemcomitans induces TNF-alpha, IL-1 beta, and IL-6 in murine macrophages. J Dent Res, 76, 1538-1547. [PubMed: 9294487] |
| Year of Identification | 1997 |
