ProGlyProt ID AU140 Organism Information Organism Name Staphylothermus marinus F1 Domain Archaea Classification Family: Desulfurococcaceae Order: Desulfurococcales Class: Thermoprotei or Crenarchaeota Division or phylum: "Crenarchaeota" Taxonomic ID (NCBI) 2280 Genome Sequence (s) GeneBank EMBL U57968 Gene Information Gene Name NCBI Gene ID Protein Information Protein Name Stable protease UniProtKB/SwissProt ID Q54437 NCBI RefSeq EMBL-CDS AAB02323.1 UniProtKB Sequence >tr|Q54437|Q54437_STAMA STABLE protease OS=Staphylothermus marinus PE=4 SV=1 MRRLLVILSLIIIVGLIMPSLSLSAPVTVGNKDLNKFTIDPNWQNKIPKKLFDDVYTNAK IKKAAFMPYGIQTVKKIMLFDSNSRTLLLIGDNSENTVRYIIQNTEKLLYKFPLLGNHVI YYVVATPDQVVKLAKYPGIYRITPSPPITKLIKLNNMIKKAEGAGSSFEIKTADNNENAT IDTNMGVKLIGATEVWREYNITGEGIVVGIVDTGIDLSNPDLGLDVIARDDNGTPLLLAY DNGLTLVTGKAVAYNGTLNTTGLTVLAFDPLYTLVYGIPVLIEAQFNYNITVGNITSQSG IYRVGLAPYLFSDTLTGYYIRTFVPVVLVDSETPGVYDEAYFDLSTAFYDLSEYMRYLEN VTLGHIYWRAPDPAWNDTSITDETPFGPGNEIVGRDFDGDGIIDFSIGTIAGYYLDSYGL ATLTYDPTTGNITLGTPGLYPGWDYQGRYLALVSDFHGHGTSVATVIASRGRVLYDLYGD GKLYRIMGVAPGAKIAGGDAWLLGNILVLEAWLAGFNIVTEEEDGYVYLSLDPFGPHRAD IISNSWGSIYINFWLQQFPGIDYRSSFMDEILAIRNYLIGDHVTIVFAAGNEGPGYSSNG APGTGLLVITAGASTLWDYTRIYGYPEGYADEVIPFSSRGPTGQGYPKPDIVNIGAFEWA STRTIDGRGYGAQPDVFGGTSEATPYTSGTLALVFQAYKEVYNTTPDPVTAKIILKSSAK DIWYPAFSQGSGRVDALKAADTVFISEWLAYVSEGIQEAFLENYYTDFGPYIGYVLPYLA DTDYYGVVKPGSSKNFTLNIVGNGAVSLSAWNTVLYKEYTVYDGVYDYSGLLFLKVPKYA YSGADYVEVVVQLENMTYPPGVFLKTPIDPLHAIILSAYDWIDYNGDGQIGYPDELHYIT FEYRVSTEAVVSISAPMEKIHGDLVLRIRPDYINVTPVKMKIVVRSFKYVPCKLMSLPNT VDVNGTASIPITINVPDNFRPGILEVRLIVDTPDKRIVVPVSILVPLIADETTTAVLGGA RSPMKYDPFAMYGLPDPVYGVWEGQDWRILPVLVTDPSITGLIVVARWASGYASDLSFLT VAPGGVFTPNGFLNVFASYKLSYDLGLVYNPSLSDQLHGKLRMYIPVKWAEPLRQIPIAI TDLSYWPPEPGLALMQYSDRMPEIYGLYRIIYGFASYSGKLLEDKLMFRIITVKSEIQYS EQFSFNNISVGNLYVKFTAGSYTPFLFADLYLYTEGYATPLAGSGSILPISILVNGTASN LAYYLVLYDYAYYLGTSPTGLYSEFTVPVMINTSATNVFNAIAVMYKYSWHAEGMYWFDF NTGEPLIISYVHPGMASATLNISNT Sequence length 1345 AA (24 AA signal peptide) Subcellular Location Surface Function Possesses peptidylglutamylhydrolyzing activity. It has both tryptic and chymotryptic activity, and is one of the most stable (thermostable) proteases. Glycosylation Status Glycosylation Type Information currently not available with us. Technique(s) used for Glycosylation Detection Carbohydrate analysis using trifluoroacetic acid and GC/MS. Literatures Reference(s) 1) Peters, J., Nitsch, M., Kuhlmorgen, B., Golbik, R., Lupas, A., Kellermann, J., Engelhardt, H., Pfander, J.P., Muller, S., Goldie, K. et al. (1995) Tetrabrachion: a filamentous archaebacterial surface protein assembly of unusual structure and extreme stability. J Mol Biol, 245, 385-401. [PubMed: 7837271] Year of Identification 1995