ProGlyProt ID AU135 Organism Information Organism Name Pyrococcus furiosus DSM 3638 Domain Archaea Classification Family: Thermococcaceae Order: Thermococcales Class: Thermococci or Protoarchaea Division or phylum: "Euryarchaeota" Taxonomic ID (NCBI) 2261 Genome Sequence (s) GeneBank AE009950.1 EMBL AE009950 Gene Information Gene Name cbtA (PF1209) NCBI Gene ID 1469079 Protein Information Protein Name CbtA (Cellobiose binding protein UniProtKB/SwissProt ID Q8U1J8 NCBI RefSeq NP_578938.1 EMBL-CDS AAL81333.1 UniProtKB Sequence >tr|Q8U1J8|Q8U1J8_PYRFU Oligopeptide ABC transporter (Oligopeptide-binding protein) OS=Pyrococcus furiosus GN=PF1209 PE=4 SV=1 MKRLVGVLIGAFVIFGVFGQVVAAQEQELPREETLYVGGGLWSQPNNFNPLIPWSAVTGT IGLIYETLFNYDPLNDKLEPWLAESGRWVSDNVYEVKLREGLTWQDGKPLTAEDVKFTFE LHKKYPGLAYHQMWEWLQEVKVIDDRTIQFVFSTPHYEEWKYLLYQIAIVPKHIWQNIDN PVEFANVDNPVGSGPYKLYKTDQMRFILVRNDNWWGIKYFGKPAPKYIVYVIVYSNNLAL SMLVKGELDWSNFFIPGVPDVKAQYGIVTWYDEPPYHLPANTAFLFLNTQKPPLDNPEFR RAIAYAINPEEIAARASQNQVTPADPTGLLIQYPAFKKIYNKEAVDKYGFKYDPQKAMEI LDKLGFKDVNGDGYREFPDGKPLKLTIIVPFGWTDWMEMIRVISEQLAIVGINVEPKFPD YSKYWDDLTKGNFDMAINNFGSNVVATPWQWFNWVLNQDVTPIGENFYNGNFGRYKNERV AELLELINVEKDENKKLQYYYELQEIFLKDLPYIPIIYNGAWFEASPEHWTNWPTAKNPY AFPISWNGYWQMGGVKVLLNIKPVKAATETTTTEEKTETIVQTVTVTPTETATSSTETGG ICGPAILVGLAVVPLLLRRRRS Sequence length 622 AA Subcellular Location Membrane Function High-affinity binding-protein-dependent ABC transport system for the uptake of cellobiose and most other β-glucosides. Glycosylation Status Glycosylation Type Information currently not available with us. Technique(s) used for Glycosylation Detection Concanavalin A (ConA) binding, Periodic acid- Schiff reagent (PAS) staining. Literatures Reference(s) 1) Koning, S.M., Elferink, M.G., Konings, W.N. and Driessen, A.J. (2001) Cellobiose uptake in the hyperthermophilic archaeon Pyrococcus furiosus is mediated by an inducible, high-affinity ABC transporter. J Bacteriol, 183, 4979-4984. [PubMed: 11489849] Year of Identification 2001