ProGlyProt IDAU107
Organism Information
Organism NameHaloferax volcanii DS2
DomainArchaea
ClassificationFamily: Halobacteriaceae
Order: Halobacteriales
Class: Halobacteria or Halomebacteria
Division or phylum: "Euryarchaeota"
Taxonomic ID (NCBI)309800
Genome Sequence (s)
GeneBankCP001953.1
EMBLCP001953
Gene Information
Gene NamelccA
NCBI Gene ID8919198
Protein Information
Protein NameLccA, an Archaeal Laccase
UniProtKB/SwissProt IDD4GPK6
NCBI RefSeqYP_003533285.1
EMBL-CDSADE01515.1
UniProtKB Sequence>tr|D4GPK6|D4GPK6_HALVD LccA multicopper oxidase (MCO) OS=Haloferax volcanii (strain ATCC 29605 / DSM 3757 / IFO 14742 / NCIMB 2012 / DS2) GN=lccA PE=4 SV=1
MTDWSRRRFLQTGAALGIAGTLPQTTTEVSAASPTLEKFVQPLPIPSVREPDGQRDGADA YEIAVTEFTQQLHPDLPETTVWGFDGSYPGPTIEADAGSPVHVRFDNSGLPSEHLFPVDD RLGGTTAENHPGYDGPVPEVRTVTHFHGLELDPANDGQSDMWTSPGGVEGPRFDSAWQEL PMEQGRTTSTYHDHTLGITRLNAYAGLLGLYSITTDAERELGLPSGDYDIPLLLQDKEFN DDGSLHYPEEFVSAFLGDTAVVNGAVWPYVEVEPRRYRFRILNGANHRSFDLQLESESGS GVPTMYQFAPGHGFLESVVPIGPNGDLDSLLLTPFERGELVVDFSDHAGETLTLANGADM GPELTDLVEFRVSDPSTPPEDASADPTSLSLPTPASYDESDARVTREMTLGTEVRNGLIT HTLNGHVFGDEDAPVYPQLGATEIWELQNESGGRHPIHLHLVTFRVIGRGPDGTQPPDPN ELGPKDTVRVDPGERVRILVTFEGYTGQFPWHCHMLEHEDNKMMIPFVVENPVADYANEE NVVDATGLTDAVGDWRNETLETEVLLEVIDQWRSGDEVA
Sequence length 579 AA
Subcellular LocationSecreted
FunctionBelongs to the family of Multicopper oxidases (MCOs). Laccases couple the oxidation of phenolic compounds to the reduction of O2.
Glycosylation Status
Glycosylation TypeInformation currently not available with us.
Technique(s) used for Glycosylation DetectionCarbohydrate content determined by phenol-sulfuric acid assay, Pro-Q Emerald 300 staining and mass shift (of 10-20 kDa) detected after deglycosylation with TFMS (trifluoromethanesulfonic acid).
Literatures
Reference(s)1) Uthandi, S., Saad, B., Humbard, M.A. and Maupin-Furlow, J.A. (2010) LccA, an archaeal laccase secreted as a highly stable glycoprotein into the extracellular medium by Haloferax volcanii. Appl Environ Microbiol, 76, 733-743. [PubMed: 19966030]
Year of Identification2010