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Oxygen Binding Proteins

OxyPred is to predict the Oxygen Binding Proteins, Which is carrying Erythrocruorin, Hemoglobin, Myoglobin, Hemerithrin, Leghemoglobin and Hemocyanin. These Proteins working as a Oxygen transport and binding throughout the animal and plant kingdom. Other organisms including Bacteria, Protozoans and Fungi all have hemoglobin like proteins, their known and predicted roles include the reversible binding of gaseous ligands.

Myoglobin: Found in the muscle tissue of many vertebrates including humans (gives muscle tissue a distinct red or dark gray color). Is very similar to hemoglobin in structure and sequence, but is not arranged in tetramers, it is a monomer and lacks cooperative binding and is used to store oxygen rather than transport it.

Hemocyanin: Second most common oxygen transporting protein found in nature. Found in the blood of many arthropods and molluscs. Uses copper prosthetic group instead of iron heme groups and is blue in color when oxygenated.

Hemerythrin: Some marine invertebrates and a few species of annelid use this iron containing non-heme protein to carry oxygen in their blood. Appears pink/violet when oxygenated, clear when not.

Erythrocruorin: Found in many annelids, including earthworms. Giant free-floating blood protein, contains many dozens even hundreds of Iron heme containing protein subunits bound together into a single protein complex with a molecular masses greater than 3.5 million daltons.

Leghemoglobin: In leguminous plants, such as alfalfa or soybeans, the nitrogen fixing bacteria in the roots are protected from oxygen by this iron heme containing, oxygen binding protein.

if using this server, please cite:
Muthukrishnan S., Garg A. and Raghava, G. P. S. (2007) OxyPred: Prediction and Classification of Oxygen-Binding Proteins Genomics, Proteomics & Bioinformatics 5:250-2