Go to Interactome Search page

Serial No.ORFAnnotation
1Rv0001, (MTV029.01), len: 507. dnaA, chromosomal relication initiator protein, identical to TR:Q59585 (EMBL:X92504) and highly similar to many eg. DNAA_ECOLI P03004 chromosomal replication initiator protein (467 aa), fasta scores; opt: 986 z-score: 1154.5 E(): (dnaA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2Rv0002, (MTV029.02-MTCY10H4.0), len: 402 aa; dnaN, dna polymerase III beta chain, almost identical to Q50790 (EMBL:X92504) dnaN (399 aa) (96.9% identity in 353 aa overlap) and highly similar to many eg. DP3B_STRCO P27903 dna polymerase iii, beta chain (ec 2. (3 (dnaN) {Mycobacterium tuberculosis H37Rv (lab strain)}
3Rv0003, (MTCY10H4.01), recF gene, len: 385, TR:E208998; contains PS00017 ATP/GTP-binding site motif A, PS00617RecF protein signature 1, PS00618 RecF protein signature 2 (recF) {Mycobacterium tuberculosis H37Rv (lab strain)}
4Rv0004hypothetical protein Rv0004 {Mycobacterium tuberculosis H37Rv (lab strain)}
5Rv0005, (MTCY10H4.03), gyrB, dna gyrase subunit b, len: 714, identical to GYRB_MYCTU P41514, contains PS00177 DNA topoisomerase II signature (gyrB) {Mycobacterium tuberculosis H37Rv (lab strain)}
6Rv0006, (MTCY10H4.04), len: 838, gyrA, dna gyrase subunita, almost identical to GYRA_MYCTU Q07702, contains PS00018EF-hand calcium-binding domain (gyrA) {Mycobacterium tuberculosis H37Rv (lab strain)}
7Rv0007hypothetical protein Rv0007 {Mycobacterium tuberculosis H37Rv (lab strain)}
8Rv0008chypothetical protein Rv0008c {Mycobacterium tuberculosis H37Rv (lab strain)}
9Rv0009, (MTCY10H4.08), peptidyl-prolyl cis-trans isomerase, len: 182, highly similar to E235739, (182 aa), (90.1% identity in 182 aa overlap). Also similar to P77949 CYCLOPHILIN SCCYPB (175 aa); E(): 0; (62.7% identity in 166 aa overlap) and to MTCY227.19c, (36 (ppiA) {Mycobacterium tuberculosis H37Rv (lab strain)}
10Rv0010chypothetical protein Rv0010c {Mycobacterium tuberculosis H37Rv (lab strain)}
11Rv0011chypothetical protein Rv0011c {Mycobacterium tuberculosis H37Rv (lab strain)}
12Rv0012hypothetical protein Rv0012 {Mycobacterium tuberculosis H37Rv (lab strain)}
13Rv0013, (MTCY10H4.13), len: 232, similar to eg M. leprae pabS, E235740 para-aminobenzoate synthase (232 aa), fasta scores, opt: 1273, E(): 0, (79.7% identity in 232 aa overlap) and to eg TRPG_AZOBR P26922 anthranilate synthase component ii (196 aa), fasta score (pabA) {Mycobacterium tuberculosis H37Rv (lab strain)}
14Rv0014c, (MTCY10H4.14c), protein kinase B, len: 626 highly similar to M. leprae MLCB1770_9 (622 aa), FASTA scores: opt: 3600 z-score: 3263.9 E(): 0; 86.4% identity in 626 aa overlap. Also similar to E235741 protein kinase pknB (315 aa), fasta scores, opt: 1839, (pknB) {Mycobacterium tuberculosis H37Rv (lab strain)}
15Rv0015c, (MTCY10H4.15c), protein kinase A, len: 431 highly similar to M. leprae MLCB1770_10, (437 aa), FASTA scores: opt: 1883 z-score: 1316.5 E(): 0; 72.1% identity in434 aa overlap. Also similar to PKNA_MYCLE protein kinase pknA (253 aa), fasta scores, opt: 15 (pknA) {Mycobacterium tuberculosis H37Rv (lab strain)}
16Rv0016c, (MTCY10H4.16c), pbpA homologue, len: 491, highly similar to M. leprae, penicillin binding protein, pbpA MLCB1770_11, (474 aa), FASTA scores: opt: 2516 z-score: 2600.4 E(): 0; 82.4% identity in 472 aa overlap. Also similar to E235825, penicillin binding (pbpA) {Mycobacterium tuberculosis H37Rv (lab strain)}
17Rv0017c, (MTCY10H4.17c), len: 469, highly similar to M. leprae MLCB1770_12, (465 aa),opt: 2475 z-score: 3029.6E(): 0; E235744 cell division protein, (81.9% identity in469 aa overlap). Also similar to MTCY270_14, (524, 32.2% identity in 369 aa overlap) (rodA) {Mycobacterium tuberculosis H37Rv (lab strain)}
18Rv0018c,(MTCY10H4.18c),len: 514,highly similar to putative phosphoprotein phosphatase in M. leprae, MLCB1770_13, (509 aa); fasta scores: opt: 2517 z-score: 1508.1 E(): 0,Also similar to YLOO PROTEIN, BSUB0009_46 Bacillus subtilis, (254 aa, 34.0% identity in 250 (ppp) {Mycobacterium tuberculosis H37Rv (lab strain)}
19Rv0019chypothetical protein Rv0019c {Mycobacterium tuberculosis H37Rv (lab strain)}
20Rv0020chypothetical protein Rv0020c {Mycobacterium tuberculosis H37Rv (lab strain)}
21Rv0021chypothetical protein Rv0021c {Mycobacterium tuberculosis H37Rv (lab strain)}
22Rv0022chypothetical protein Rv0022c {Mycobacterium tuberculosis H37Rv (lab strain)}
23Rv0023hypothetical protein Rv0023 {Mycobacterium tuberculosis H37Rv (lab strain)}
24Rv0024hypothetical protein Rv0024 {Mycobacterium tuberculosis H37Rv (lab strain)}
25Rv0025hypothetical protein Rv0025 {Mycobacterium tuberculosis H37Rv (lab strain)}
26Rv0026hypothetical protein Rv0026 {Mycobacterium tuberculosis H37Rv (lab strain)}
27Rv0027hypothetical protein Rv0027 {Mycobacterium tuberculosis H37Rv (lab strain)}
28Rv0028hypothetical protein Rv0028 {Mycobacterium tuberculosis H37Rv (lab strain)}
29Rv0029hypothetical protein Rv0029 {Mycobacterium tuberculosis H37Rv (lab strain)}
30Rv0030hypothetical protein Rv0030 {Mycobacterium tuberculosis H37Rv (lab strain)}
31Rv0031hypothetical protein Rv0031 {Mycobacterium tuberculosis H37Rv (lab strain)}
32Rv0032, (MTCY10H4.32),, len: 771, bioF2, c-terminal similar to eg BIOF_BACSU P53556 8-amino-7-oxononanoate synthase (389 aa), fasta scores, opt: 775, E(): 0, (37.9% identity in 346 aa overlap). Also similar to BIOF in MTCY336_35 (M. tuberculosis), AF041819_4 (M (bioF2) {Mycobacterium tuberculosis H37Rv (lab strain)}
33Rv0033hypothetical protein Rv0033 {Mycobacterium tuberculosis H37Rv (lab strain)}
34Rv0034hypothetical protein Rv0034 {Mycobacterium tuberculosis H37Rv (lab strain)}
35Rv0035, (MTCY10H4.35), , len: 562, fadD34, probable acyl-CoA synthase, similar to many e.g. MBU75685_1 M. bovisacyl-CoA synthase (582 aa) FASTA scores: opt: 408 z-score:490.7 E(): 8.2e-20, also similar to G1171128 saframycin mx1 synthetase B (1770 aa), fasta sc (fadD34) {Mycobacterium tuberculosis H37Rv (lab strain)}
36Rv0036chypothetical protein Rv0036c {Mycobacterium tuberculosis H37Rv (lab strain)}
37Rv0037chypothetical protein Rv0037c {Mycobacterium tuberculosis H37Rv (lab strain)}
38Rv0038hypothetical protein Rv0038 {Mycobacterium tuberculosis H37Rv (lab strain)}
39Rv0039chypothetical protein Rv0039c {Mycobacterium tuberculosis H37Rv (lab strain)}
40Rv0040chypothetical protein Rv0040c {Mycobacterium tuberculosis H37Rv (lab strain)}
41Rv0041, (MTCY21D4.04), putative leucyl-trna synthetase, len: 969, similar to eg SYL_BACSU P36430 leucyl-trna synthetase (804 aa), fasta scores, opt: 714, E(): 3.1e-38, (43.7% identity in 938 aa overlap); contains PS00178 Aminoacyl-transfer RNA synthetases class (leuS) {Mycobacterium tuberculosis H37Rv (lab strain)}
42Rv0042chypothetical protein Rv0042c {Mycobacterium tuberculosis H37Rv (lab strain)}
43Rv0043chypothetical protein Rv0043c {Mycobacterium tuberculosis H37Rv (lab strain)}
44Rv0044chypothetical protein Rv0044c {Mycobacterium tuberculosis H37Rv (lab strain)}
45Rv0045chypothetical protein Rv0045c {Mycobacterium tuberculosis H37Rv (lab strain)}
46Rv0046chypothetical protein Rv0046c {Mycobacterium tuberculosis H37Rv (lab strain)}
47Rv0047chypothetical protein Rv0047c {Mycobacterium tuberculosis H37Rv (lab strain)}
48Rv0048chypothetical protein Rv0048c {Mycobacterium tuberculosis H37Rv (lab strain)}
49Rv0049hypothetical protein Rv0049 {Mycobacterium tuberculosis H37Rv (lab strain)}
50Rv0050, (MTCY21D4.13), len: 678, Probable penicillin-binding protein, ponA homologue, highly similar to many, e.g. M. leprae MSGDNAB_6 Mycobacterium leprae cosmid L222 D (686 aa), 82.3% identity in 679 aa overlap. (ponA) {Mycobacterium tuberculosis H37Rv (lab strain)}
51Rv0051hypothetical protein Rv0051 {Mycobacterium tuberculosis H37Rv (lab strain)}
52Rv0052hypothetical protein Rv0052 {Mycobacterium tuberculosis H37Rv (lab strain)}
53Rv0053, (MTCY21D4.16), len: 96, ribosomal protein S6, highly similar to many, e.g. RS6_MYCLE P46389 30s ribosomalprotein s6 (96 aa) , fasta scores,opt: 570, E(): 1.1e-36, (91.7% identity in 96 aa overlap); contains PS01048 Ribosomal protein S6 signature (rpsF) {Mycobacterium tuberculosis H37Rv (lab strain)}
54Rv0054, (MTCY21D4.17), len: 164, highly similar to eg SSB_MYCLE P46390 single-strand binding protein homologue(140 aa), fasta scores, opt: 792, E(): 0, (92.6% identity in 135 aa overlap). Also similar to MTV008_34, E (): 1.1e-06. (ssb) {Mycobacterium tuberculosis H37Rv (lab strain)}
55Rv0055, (MTCY21D4.18), len: 84, similar to eg RS18_BACST P10806 30s ribosomal protein s18 (bs21) (77 aa), fasta scores, opt: 220, E(): 4e-10, (52.2% identity in 67 aa overlap). \Also similar to MTCY63A_5 (rpsR) {Mycobacterium tuberculosis H37Rv (lab strain)}
56Rv0056, (MTCY21D4.19), len: 152, highly similar to RL9_MYCLE P46385 50s ribosomal protein l9 (152 aa), fasta scores, opt: 847, E(): 0, (88.7% identity in 150 aa overlap); contains PS00651 Ribosomal protein L9 signature (rplI) {Mycobacterium tuberculosis H37Rv (lab strain)}
57Rv0057hypothetical protein Rv0057 {Mycobacterium tuberculosis H37Rv (lab strain)}
58Rv0058, (MTV030.01-MTCY21D4.21), dnaB, replicative dna helicase, len: 874 aa; contains an intein (position 61630..62838) similar to, and in the same position as, those in Sycnechocystis and Rhodothermus marinus (See Liu X.Q., HuZ. Proc. Natl. Acad. Sci. U.S.A. (dnaB) {Mycobacterium tuberculosis H37Rv (lab strain)}
59Rv0059hypothetical protein Rv0059 {Mycobacterium tuberculosis H37Rv (lab strain)}
60Rv0060hypothetical protein Rv0060 {Mycobacterium tuberculosis H37Rv (lab strain)}
61Rv0061hypothetical protein Rv0061 {Mycobacterium tuberculosis H37Rv (lab strain)}
62Rv0062, (MTV030.05), possible cellulase, len: 380; celA, similar to many eg. GUN1_STRHA P33682 endoglucanase 1precursor (ec 3.2.1.4) (cellulase) from STREPTOMYCES HALSTEDII (321 aa), fasta scores; opt: 702 z-score: 625.7 E(): 1.2e-27, 38.9% identity in 319 aa o (celA) {Mycobacterium tuberculosis H37Rv (lab strain)}
63Rv0063hypothetical protein Rv0063 {Mycobacterium tuberculosis H37Rv (lab strain)}
64Rv0064hypothetical protein Rv0064 {Mycobacterium tuberculosis H37Rv (lab strain)}
65Rv0065hypothetical protein Rv0065 {Mycobacterium tuberculosis H37Rv (lab strain)}
66Rv0066c, (MTV030.09c), icd2, isocitrate dehydrogenase, len: 745 aa; highly similar to many members of the monomeric-type family of IDH eg. IDH_AZOVI P16100 isocitrate dehydrogenase (nadp) (ec 1.1.1.42) (741 aa), fasta scores opt:3106 z-score: 4023.1 E(): 0, 61.4 (icd2) {Mycobacterium tuberculosis H37Rv (lab strain)}
67Rv0067chypothetical protein Rv0067c {Mycobacterium tuberculosis H37Rv (lab strain)}
68Rv0068hypothetical protein Rv0068 {Mycobacterium tuberculosis H37Rv (lab strain)}
69Rv0069c, (MTV030.12c), sdaA, l-serine dehydratase, len: 461 aa; highly similar to many eg. SDHL_ECOLI P16095 l-serine dehydratase 1 (ec 4.2.1.13) (454 aa), fasta scores;opt: 1381 z-score: 1491.1 E(): 0, 51.1% identity in 460 aaoverlap (sdaA) {Mycobacterium tuberculosis H37Rv (lab strain)}
70Rv0070c, (MTV030.13c), glyA2, serine hydroxymethyltransferase, len: 425 aa; highly similar to many eg. GLYA_ECOLI P00477 serine hydroxymethyltransferase (ec 2.1.2.1) (417aa), fasta scores; opt: 1462 z-score: 1722.1 E(): 0, 54.3%identity in 416 aa overlap. Also h (glyA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
71Rv0071hypothetical protein Rv0071 {Mycobacterium tuberculosis H37Rv (lab strain)}
72Rv0072hypothetical protein Rv0072 {Mycobacterium tuberculosis H37Rv (lab strain)}
73Rv0073hypothetical protein Rv0073 {Mycobacterium tuberculosis H37Rv (lab strain)}
74Rv0074hypothetical protein Rv0074 {Mycobacterium tuberculosis H37Rv (lab strain)}
75Rv0075hypothetical protein Rv0075 {Mycobacterium tuberculosis H37Rv (lab strain)}
76Rv0076chypothetical protein Rv0076c {Mycobacterium tuberculosis H37Rv (lab strain)}
77Rv0077chypothetical protein Rv0077c {Mycobacterium tuberculosis H37Rv (lab strain)}
78Rv0078hypothetical protein Rv0078 {Mycobacterium tuberculosis H37Rv (lab strain)}
79Rv0079hypothetical protein Rv0079 {Mycobacterium tuberculosis H37Rv (lab strain)}
80Rv0080hypothetical protein Rv0080 {Mycobacterium tuberculosis H37Rv (lab strain)}
81Rv0081hypothetical protein Rv0081 {Mycobacterium tuberculosis H37Rv (lab strain)}
82Rv0082hypothetical protein Rv0082 {Mycobacterium tuberculosis H37Rv (lab strain)}
83Rv0083hypothetical protein Rv0083 {Mycobacterium tuberculosis H37Rv (lab strain)}
84Rv0084, (MTCY251.02), len: 316,hycD, similar to HYCD_ECOLI P16430 formate hydrogenlyase subunit 4 (307 aa) FASTA scores, opt: 570, z-score: 591.6, E(): 2.1e-26, (33.8% identity in 305 aa overlap) and NUOH_ECOLI P33603nadh dehydrogenase i chain h (325 aa) FASTA (hycD) {Mycobacterium tuberculosis H37Rv (lab strain)}
85Rv0085, (MTCY251.03), len: 220. hycP, similar to sp|P77524|HYFE_ECOLI HYDROGENASE-4 COMPONENT E (216 aa),FASTA scores: opt: 204 z-score: 272.1 E():1.2e-07; 25.5% identity in 216 aa overlap (hycP) {Mycobacterium tuberculosis H37Rv (lab strain)}
86Rv0086, (MTCY251.04), oxidoreductase, len: 488, hycQ, most similar to sp|P77437|HYFF_ECOLI HYDROGENASE-4 COMPONENT F(EC 1.- (526 aa), FASTA scores: opt: 948 z-score: 1117.4 E(): 0; 35.9% identity in 493 aa overlap. Also similarto E. coli d9087711 & NUOL_ECOLI P (hycQ) {Mycobacterium tuberculosis H37Rv (lab strain)}
87Rv0087, (MTCY251.05), oxidoreductase, len: 492,hycE, similar to HYCE_ECOLI P16431 formate hydrogenlyase subunit 5 (569 aa) FASTA scores, opt: 680, z-score: 808.1, E(): 1.8e-38, (31.2% identity in 449 aa overlap) and to NUOD_ECOLI P33600 nadh dehydrogenase i cha (hycE) {Mycobacterium tuberculosis H37Rv (lab strain)}
88Rv0088hypothetical protein Rv0088 {Mycobacterium tuberculosis H37Rv (lab strain)}
89Rv0089hypothetical protein Rv0089 {Mycobacterium tuberculosis H37Rv (lab strain)}
90Rv0090hypothetical protein Rv0090 {Mycobacterium tuberculosis H37Rv (lab strain)}
91Rv0091hypothetical protein Rv0091 {Mycobacterium tuberculosis H37Rv (lab strain)}
92Rv0092, (MTCY251.11), len: 761,ctpA, cation-transportingatpase, highly similar to CTPA_MYCLE P46839, cation-transporting p-type atpase a (780 aa), FASTA scores, opt: 3454, z-score: 3721.3 E(): 0, (74.4% identity in 741 aa overlap); contains PS01047 Heavy-metal- (ctpA) {Mycobacterium tuberculosis H37Rv (lab strain)}
93Rv0093chypothetical protein Rv0093c {Mycobacterium tuberculosis H37Rv (lab strain)}
94Rv0094chypothetical protein Rv0094c {Mycobacterium tuberculosis H37Rv (lab strain)}
95Rv0095chypothetical protein Rv0095c {Mycobacterium tuberculosis H37Rv (lab strain)}
96Rv0096, (MTCY251.15), len: 463, Unknown, member of the PPE family, similar to gp|Z46257|MLACEA_3 M.leprae aceA gene for isocitrate l (438 aa); FASTA scores: opt: 1207 z-score: 954.2 E(): 0; 55.3% identity in 380 aa overlap. Also similar to gp|Z97559|MTCY261_19 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
97Rv0097hypothetical protein Rv0097 {Mycobacterium tuberculosis H37Rv (lab strain)}
98Rv0098hypothetical protein Rv0098 {Mycobacterium tuberculosis H37Rv (lab strain)}
99Rv0099, (MTCY251.18), len: 540.fadD10, Ligase, mostsimilar to M. leprae MLACEA_4/sp|Q50176|Q50176 LONG CHAIN FATTY ACID-COA LIGASE. (532 aa), FASTA scores: opt: 2580 z-score:2947.6 E(): 0; 74.6% identity in 531 aa overlap. Alsosimilar to ACSA_BACSU P39062 acety (fadD10) {Mycobacterium tuberculosis H37Rv (lab strain)}
100Rv0100hypothetical protein Rv0100 {Mycobacterium tuberculosis H37Rv (lab strain)}
101Rv0101, (MTCY251.20), len: 2512, peptide synthetasesimilar to gp|Z46257|MLACEA_5 M.leprae aceA gene for isocitrate l (1401 aa), FASTA scores: opt: 4268 z-score: 4563.7E(): 0; 65.7% identity in 1091 aa overlap. Also similar toSRF1_BACSU P27206 surfactin syntheta (nrp) {Mycobacterium tuberculosis H37Rv (lab strain)}
102Rv0102hypothetical protein Rv0102 {Mycobacterium tuberculosis H37Rv (lab strain)}
103Rv0103c, (MTCY251.22c), ctpB, cation transport atpase, len: 752, highly similar to CTPB_MYCLE P46840, cation-transporting p-type atpase b, (750 aa) FASTA scores, opt: 3615, z-score: 3838.0, E(): 0, (76.5% identity in 752 aa overlap); Also highly similar to gp|Z4 (ctpB) {Mycobacterium tuberculosis H37Rv (lab strain)}
104Rv0104hypothetical protein Rv0104 {Mycobacterium tuberculosis H37Rv (lab strain)}
105Rv0105c, (MTCY251.24c), ribosomal protein, len: 94 similar to RL28_ECOLI P02428 50s ribosomal protein l28, (77aa) FASTA scores, opt: 167, z-score: 224.1, E(): 6.2e-06, (40.7% identity in 59 aa overlap). Also similar to MTCY63A_2. (rpmB) {Mycobacterium tuberculosis H37Rv (lab strain)}
106Rv0106hypothetical protein Rv0106 {Mycobacterium tuberculosis H37Rv (lab strain)}
107Rv0107c, (MTCY251.26c-MTV031.01c), len: 1632, ctpI,similar to cation transport atpases, eg ATA1_SYNY P37367 cation-transporting atpase pma1 (915 aa) FASTA scores, opt:603, z-score: 636.5, E(): 6.6e-29, (32.4% identity in 710 aaoverlap), contains PS00154 E1-E2 AT (ctpI) {Mycobacterium tuberculosis H37Rv (lab strain)}
108Rv0108chypothetical protein Rv0108c {Mycobacterium tuberculosis H37Rv (lab strain)}
109Rv0109, (MTV031.03c), len: 496. Member of M. tuberculosis PE-family, Gly-, Ala-rich PGRS subfamily. FASTA scores: sp|Q50615|Y0DP_MYCTU HYPOTHETICAL GLYCINE-RICH 40.8 KD (498 aa) opt: 1772 z-score: 1133.2 E(): 0; 57.3% identity in 513 aa overlap. TBparse score i (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
110Rv0110hypothetical protein Rv0110 {Mycobacterium tuberculosis H37Rv (lab strain)}
111Rv0111hypothetical protein Rv0111 {Mycobacterium tuberculosis H37Rv (lab strain)}
112Rv0112, (MTV031.06), len: 318. gca, Possible dehydrogenase similar to many GDP-MANNOSE 4,6-DEHYDRATASE genes e.g. gp|U18320|PAU18320_1 Pseudomonas aeruginosa GDP-D-mann (323 aa) opt: 415 z-score:513.2 E(): 4.4e-21; 27.0% identity in 318 aa overlap. Contains Sho (gca) {Mycobacterium tuberculosis H37Rv (lab strain)}
113Rv0113, (MTV031.07), len: 196, gmhA, Probable phosphoheptose isomerase similar to many. e.g H. pylori AE005. FASTA scores: gp|AE0005|HPAE000596_11 Helicobacter pylori from bases (192 aa) opt: 451 z-score: 573.4 E(): 1.9e-24. 45.1% identity in162 aa overlap (gmhA) {Mycobacterium tuberculosis H37Rv (lab strain)}
114Rv0114hypothetical protein Rv0114 {Mycobacterium tuberculosis H37Rv (lab strain)}
115Rv0115hypothetical protein Rv0115 {Mycobacterium tuberculosis H37Rv (lab strain)}
116Rv0116chypothetical protein Rv0116c {Mycobacterium tuberculosis H37Rv (lab strain)}
117Rv0117, (MTV031.11), len: 314. OxyS protein, probable regulatory protein. LysR family signature at N-terminus. FASTA scores: gp|AJ0001|MTAJ188_1 Mycobacterium tuberculosis oxyS gene (314 aa) opt: 2014 z-score: 2474.5 E(): 0. 99.7% identity in 314 aa overlap sco (oxyS) {Mycobacterium tuberculosis H37Rv (lab strain)}
118Rv0118c, (MTV031.12c), Len: 582, Probable oxalyl-CoA decarboxylase similar to many. Also similar to mycobacterial IlvB proteins e.g. Mycobacterium leprae MLCB1788.46c (548 aa), unknown TPP-requiring enzyme, and MTCY1A11.23c (547aa). FASTA scores: gp|M77128|OXAOX (oxcA) {Mycobacterium tuberculosis H37Rv (lab strain)}
119Rv0119, (MTV031.13-MTCI418B.01), len: 525.fadD7, PossibleCoenzyme A-ligase similar to 4-coumarate:CoA ligase of manyorganisms e.g. PTU39405_1 (537 aa). Contains PS00455Putative AMP-binding domain signature. FASTA scores: gp|U39405|PTU39405_1 Pinus taeda xylem 4 (fadD7) {Mycobacterium tuberculosis H37Rv (lab strain)}
120Rv0120c, (MTCI418B.02c), fusA2, len: 714. Elongation factor g, similar to eg. EFG_ECOLI P02996 elongation factor g (ef-g). Escherichia coli (703 aa), fasta scores; opt:1049 z-score: 1105.5 E(): 0, 32.5% identity in 717 aa overlap. Contains PS00017 ATP/GTP-bindin (fusA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
121Rv0121chypothetical protein Rv0121c {Mycobacterium tuberculosis H37Rv (lab strain)}
122Rv0122hypothetical protein Rv0122 {Mycobacterium tuberculosis H37Rv (lab strain)}
123Rv0123hypothetical protein Rv0123 {Mycobacterium tuberculosis H37Rv (lab strain)}
124Rv0124, (MTCI418B.06), len: 487. Member of the PGRSfamily of Glycine-rich proteins, highly similar to eg. Y0DP_MYCTU Q50615 hypothetical glycine-rich 40.8 kd protein (498 aa), fasta scores; opt: 1730 z-score: 1201.5 E(): 0, 60.7% identity in 504 aa overlap (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
125Rv0125, (MTCI418B.07), len: 355. probable serine protease, highly similar to Mycobacterium paratuberculosis Q50320 34KDA protein precursor (361 aa), fasta scores; opt: 1689 z-score: 1566.8 E(): 0, 70.7% identity in 362 aa overlapand to eg. HHOB_ECOLI P31137 pro (pepA) {Mycobacterium tuberculosis H37Rv (lab strain)}
126Rv0126hypothetical protein Rv0126 {Mycobacterium tuberculosis H37Rv (lab strain)}
127Rv0127hypothetical protein Rv0127 {Mycobacterium tuberculosis H37Rv (lab strain)}
128Rv0128hypothetical protein Rv0128 {Mycobacterium tuberculosis H37Rv (lab strain)}
129Rv0129c, (MTCI5.03c), len: 340. fbpC2, Antigen 85c,almost identical to A85C_MYCTU P31953 antigen 85-c precursor (85c)(antigen (340 aa), fasta scores, opt: 2359, E(): 0, (99.7%identity in 340 aa overlap), similar to A85C_MYCLE Q05862 antigen 85-c precursor (85c) (fbpC2) {Mycobacterium tuberculosis H37Rv (lab strain)}
130Rv0130hypothetical protein Rv0130 {Mycobacterium tuberculosis H37Rv (lab strain)}
131Rv0131c, (MTCI5.05c), len: 447 aa, fadE1, Probable acyl-CoA dehydrogenase, similar to many, e.g. ACDS_HUMAN P16219 acyl-coa dehydrogenase, short-chain specific precursor (412 aa), fasta scores, opt: 522, E(): 1.4e-23, (30.1% identity in 425 aa overlap). Also hig (fadE1) {Mycobacterium tuberculosis H37Rv (lab strain)}
132Rv0132chypothetical protein Rv0132c {Mycobacterium tuberculosis H37Rv (lab strain)}
133Rv0133hypothetical protein Rv0133 {Mycobacterium tuberculosis H37Rv (lab strain)}
134Rv0134, (MTCI5.08), len: 300 aa,ephE, similar to eg Q39856 epoxide hydrolase (341 aa), fasta scores, opt: 369, E(): 4.6e-17, (27.2% identity in 335 aa overlap), also similarto MTCY09F9.26c (29.5% identity in 346 aa overlap) (ephF) {Mycobacterium tuberculosis H37Rv (lab strain)}
135Rv0135chypothetical protein Rv0135c {Mycobacterium tuberculosis H37Rv (lab strain)}
136Rv0136hypothetical protein Rv0136 {Mycobacterium tuberculosis H37Rv (lab strain)}
137Rv0137chypothetical protein Rv0137c {Mycobacterium tuberculosis H37Rv (lab strain)}
138Rv0138hypothetical protein Rv0138 {Mycobacterium tuberculosis H37Rv (lab strain)}
139Rv0139hypothetical protein Rv0139 {Mycobacterium tuberculosis H37Rv (lab strain)}
140Rv0140hypothetical protein Rv0140 {Mycobacterium tuberculosis H37Rv (lab strain)}
141Rv0141chypothetical protein Rv0141c {Mycobacterium tuberculosis H37Rv (lab strain)}
142Rv0142hypothetical protein Rv0142 {Mycobacterium tuberculosis H37Rv (lab strain)}
143Rv0143chypothetical protein Rv0143c {Mycobacterium tuberculosis H37Rv (lab strain)}
144Rv0144hypothetical protein Rv0144 {Mycobacterium tuberculosis H37Rv (lab strain)}
145Rv0145hypothetical protein Rv0145 {Mycobacterium tuberculosis H37Rv (lab strain)}
146Rv0146hypothetical protein Rv0146 {Mycobacterium tuberculosis H37Rv (lab strain)}
147Rv0147hypothetical protein Rv0147 {Mycobacterium tuberculosis H37Rv (lab strain)}
148Rv0148hypothetical protein Rv0148 {Mycobacterium tuberculosis H37Rv (lab strain)}
149Rv0149hypothetical protein Rv0149 {Mycobacterium tuberculosis H37Rv (lab strain)}
150Rv0150chypothetical protein Rv0150c {Mycobacterium tuberculosis H37Rv (lab strain)}
151Rv0151c, (MTCI5.25c), unknown, len: 588 aa, N-terminal region similar eg to PE_PGRS family MTV032_2 hypothetical glycine-rich protein, (468 aa) protein (opt: 1125 z-score: 996.2 E(): 0; 46.3% identity in 456 aa overlap, or MTCY493_24(42.5% identity in 558 aa ove (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
152Rv0152c, (MTCI5.26c), unknown, len: 525 aa, unknownsimilar to ORF downstream, gp|Z92770|MTCI5_25 Mycobacteriumtuberculosis cosmid I (588 aa); opt: 1492 z-score: 1466.5E(): 0; 54.7% identity in 464 aa overlap (54.7 % identityin464 aa overlap) and to many other PE (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
153Rv0153chypothetical protein Rv0153c {Mycobacterium tuberculosis H37Rv (lab strain)}
154Rv0154c, (MTCI5.28c), len: 403 aa, fadE2, similar to the C-terminal region of sp|O01590|O01590 ACYL-COA DEHYDROGENASE (974 aa); FASTA scores: opt: 1150 z-score: 1384.7 E(): 0;50.0% identity in 402 aa overlap. Also similar to eg ACDS_MEGEL Q06319 acyl-coa dehydro (fadE2) {Mycobacterium tuberculosis H37Rv (lab strain)}
155Rv0155, (MTCI5.29), pntAA, len: 366 aa, similar eg to PNTA_ECOLI P07001 nad(p) transhydrogenase subunit alpha (510 aa), fasta scores, opt: 921, E(): 0, (42.1% identity in 361 aa overlap) and to PROTON-TRANSLOCATING NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE SUBUN (pntAA) {Mycobacterium tuberculosis H37Rv (lab strain)}
156Rv0156, (MTCI5.30), pntAB, len: 110 aa, similar tosp|Q59764|Q59764 NICOTINAMIDE NUCLEOTIDE TRANSHYDROGEN SUBUNIT PNTAB (139 aa)opt: 247 z-score: 340.5 E(): 1.9e-11, 45.5% identity in 88 aa overlap (pntAB) {Mycobacterium tuberculosis H37Rv (lab strain)}
157Rv0157, (MTCI5.31), len: 475 aa, similar to eg PNTBRHODOSPIRILLUM RUBRUM Q59763 PROTON-TRANSLOCATING NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT beta (464 aa), fasta scores,opt: 1344, E(): 0, (46.4% identity in 472 aa overlap) (pntB) {Mycobacterium tuberculosis H37Rv (lab strain)}
158Rv0158hypothetical protein Rv0158 {Mycobacterium tuberculosis H37Rv (lab strain)}
159Rv0159c, (MTV032.02c), len: 468. Member of M. tuberculosis PE family, similar to many other PE proteins e.g O06828 (528 aa). FASTA scores: sptr|O06828|O06828 HYPOTHETICAL 54.6 KD PROTEIN (528 aa) opt: 1163 z-score: 1226.5 E(): 0; 45.8% identity in 467 aa overlap (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
160Rv0160c, (MTV032.03c), len: 502. Member of M. tuberculosis PE family, similar to many other PE proteins e.g. O06801 (525 aa). Also highly similar to downstream ORF MTV032_2. Similar in C-terminal region to MTCI5.26c (525 aa). FASTA scores: sptr|O06801|O06801 HYP (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
161Rv0161hypothetical protein Rv0161 {Mycobacterium tuberculosis H37Rv (lab strain)}
162Rv0162c, (MTCI28.02c), len: 383,adhE, alcohol dehydrogenase, similar to eg.ADH_MACMU P28469 alcohol dehydrogenase alpha chain (374 aa), opt: 619 z-score: 741.5 E(): 0, 34.7%identity in 363 aa overlapContains PS00059 Zinc-containingalcohol dehydrogenases signatur (adhE) {Mycobacterium tuberculosis H37Rv (lab strain)}
163Rv0163hypothetical protein Rv0163 {Mycobacterium tuberculosis H37Rv (lab strain)}
164Rv0165chypothetical protein Rv0165c {Mycobacterium tuberculosis H37Rv (lab strain)}
165Rv0166, (MTCI28.06), fadD5, probable fatty-acid CoAligase len: 554; similar to several eg. LCFA_ECOLI P29212 long-chain-fatty-acid--coa ligase (561 aa), fasta scores; opt: 612 z-score: 764.6 E(): 0, 29.4% identity in 534 aa overlap. Contains PS00455 Putative AM (fadD5) {Mycobacterium tuberculosis H37Rv (lab strain)}
166Rv0167hypothetical protein Rv0167 {Mycobacterium tuberculosis H37Rv (lab strain)}
167Rv0168hypothetical protein Rv0168 {Mycobacterium tuberculosis H37Rv (lab strain)}
168Rv0169, (MTCI28.09), mce, involved in entry and survival inside macrophages, len: 298 aa, identical to but longer than TR:P72013 M. tuberculosis Mcep protein (EM_BA:MTMCE X70901). See Arruda et al, Science v261 p1454. Contains avery hydrophobic region around re (mce1) {Mycobacterium tuberculosis H37Rv (lab strain)}
169Rv0170hypothetical protein Rv0170 {Mycobacterium tuberculosis H37Rv (lab strain)}
170Rv0171hypothetical protein Rv0171 {Mycobacterium tuberculosis H37Rv (lab strain)}
171Rv0172hypothetical protein Rv0172 {Mycobacterium tuberculosis H37Rv (lab strain)}
172Rv0173, (MTCI28.13), unknown, len: 390 aa; lprK, similar to MTCY19H5_29, and MTV023_2, MTV051.08 and other M.hypothetical M. tuberculosis proteins. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site (lprK) {Mycobacterium tuberculosis H37Rv (lab strain)}
173Rv0174hypothetical protein Rv0174 {Mycobacterium tuberculosis H37Rv (lab strain)}
174Rv0175hypothetical protein Rv0175 {Mycobacterium tuberculosis H37Rv (lab strain)}
175Rv0176hypothetical protein Rv0176 {Mycobacterium tuberculosis H37Rv (lab strain)}
176Rv0177hypothetical protein Rv0177 {Mycobacterium tuberculosis H37Rv (lab strain)}
177Rv0178hypothetical protein Rv0178 {Mycobacterium tuberculosis H37Rv (lab strain)}
178Rv0179c, (MTCI28.19c), len: 369 aa; possible lipoprotein, contains possible M-terminal signal sequencem and contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site (lprO) {Mycobacterium tuberculosis H37Rv (lab strain)}
179Rv0180chypothetical protein Rv0180c {Mycobacterium tuberculosis H37Rv (lab strain)}
180Rv0181chypothetical protein Rv0181c {Mycobacterium tuberculosis H37Rv (lab strain)}
181Rv0182c, (MTCI28.22c), len: 370; sigG, probable RNA polymerase sigma subunit, similar to many. e.g. RPOE_MYCTU RNA POLYMERASE SIGMA-E . Contains PS01063 Sigma-70 factors ECF subfamily signature and probable helix-turn helix motiffrom aa 206-227. Start site uncer (sigG) {Mycobacterium tuberculosis H37Rv (lab strain)}
182Rv0183hypothetical protein Rv0183 {Mycobacterium tuberculosis H37Rv (lab strain)}
183Rv0184hypothetical protein Rv0184 {Mycobacterium tuberculosis H37Rv (lab strain)}
184Rv0185hypothetical protein Rv0185 {Mycobacterium tuberculosis H37Rv (lab strain)}
185Rv0186, (MTCI28.25b), len: 691, bglS, probable beta-glucosidase, similar to many eg. BGLS_AGRTU P27034 beta-glucosidase (ec 3.2.1.21) (818 aa), fasta scores; opt: 643 z-score:934.4 E(): 0, 32.5% identity in 842 aa overlap. Contains possible N-terminal signal se (bglS) {Mycobacterium tuberculosis H37Rv (lab strain)}
186Rv0187hypothetical protein Rv0187 {Mycobacterium tuberculosis H37Rv (lab strain)}
187Rv0188hypothetical protein Rv0188 {Mycobacterium tuberculosis H37Rv (lab strain)}
188Rv0189c, (MTCI28.28c), ilvD, dihydroxy-acid dehydratase, len: 575 aa; similar to many eg.ILVD_LACLA Q02139 dihydroxy-acid dehydratase (ec 4.2.1.9) (dad) (570 aa), fasta scores; opt: 1605 z-score: 1582.6 E(): 0, 46.0% identity in561 aa overlap. Contains PS00886 D (ilvD) {Mycobacterium tuberculosis H37Rv (lab strain)}
189Rv0190hypothetical protein Rv0190 {Mycobacterium tuberculosis H37Rv (lab strain)}
190Rv0191hypothetical protein Rv0191 {Mycobacterium tuberculosis H37Rv (lab strain)}
191Rv0192hypothetical protein Rv0192 {Mycobacterium tuberculosis H37Rv (lab strain)}
192Rv0193chypothetical protein Rv0193c {Mycobacterium tuberculosis H37Rv (lab strain)}
193Rv0194hypothetical protein Rv0194 {Mycobacterium tuberculosis H37Rv (lab strain)}
194Rv0195hypothetical protein Rv0195 {Mycobacterium tuberculosis H37Rv (lab strain)}
195Rv0196hypothetical protein Rv0196 {Mycobacterium tuberculosis H37Rv (lab strain)}
196Rv0197hypothetical protein Rv0197 {Mycobacterium tuberculosis H37Rv (lab strain)}
197Rv0198chypothetical protein Rv0198c {Mycobacterium tuberculosis H37Rv (lab strain)}
198Rv0199hypothetical protein Rv0199 {Mycobacterium tuberculosis H37Rv (lab strain)}
199Rv0200hypothetical protein Rv0200 {Mycobacterium tuberculosis H37Rv (lab strain)}
200Rv0201chypothetical protein Rv0201c {Mycobacterium tuberculosis H37Rv (lab strain)}
201Rv0202c, (MTV033.10c), len: 966. Probable membrane transport protein equivalent to Mycobacterium leprae MLCL622.16c (1014 aa) and similar to several putative transport proteins e.g. Bacillus subtilis P96687 (724 aa). FASTA scores: Z95398|MLCL622_16 (1014 aa) opt (mmpL11) {Mycobacterium tuberculosis H37Rv (lab strain)}
202Rv0203hypothetical protein Rv0203 {Mycobacterium tuberculosis H37Rv (lab strain)}
203Rv0204chypothetical protein Rv0204c {Mycobacterium tuberculosis H37Rv (lab strain)}
204Rv0205hypothetical protein Rv0205 {Mycobacterium tuberculosis H37Rv (lab strain)}
205Rv0206c, (MTV033.14c-MTCY08D5.01c), len: 944. Possible mebrane transport protein equivalent to Mycobacterium leprae MLCL622.18c (955 aa). FASTA scores: Z95398|MLCL622_18(955 aa) opt: 806 z-score: 520.0 E(): 1.8e-21; 57.2% identity in 243 aa overlap. TBparse scor (mmpL3) {Mycobacterium tuberculosis H37Rv (lab strain)}
206Rv0207chypothetical protein Rv0207c {Mycobacterium tuberculosis H37Rv (lab strain)}
207Rv0208chypothetical protein Rv0208c {Mycobacterium tuberculosis H37Rv (lab strain)}
208Rv0209hypothetical protein Rv0209 {Mycobacterium tuberculosis H37Rv (lab strain)}
209Rv0210hypothetical protein Rv0210 {Mycobacterium tuberculosis H37Rv (lab strain)}
210Rv0211, (MTCY08D5.06),len: 606, pckA, highly similar eg to PPCK_NEOFR P22130 phosphoenolpyruvate carboxykinase (gt (608 aa), fasta scores, opt: 2287, E(): 0, (55.9% identity in 598 aa overlap); equivalent to gp|Z95398|MLCL622_21 Mycobacterium leprae cosmid L622 (pckA) {Mycobacterium tuberculosis H37Rv (lab strain)}
211Rv0212c, (MTCY08D5.07c), len: 323 aa, similar to transcriptional regulators eg NADR_ECOLI P27278 transcriptional regulator nadr. esche (410 aa), fasta scores, opt: 377, E(): 1e-17, (31.1% identity in 347 aa overlap); contains PS00017 ATP/GTP-binding site motif A (nadR) {Mycobacterium tuberculosis H37Rv (lab strain)}
212Rv0213chypothetical protein Rv0213c {Mycobacterium tuberculosis H37Rv (lab strain)}
213Rv0214, (MTCY08D5.09), len: 537 aa,fadD4, some similaritywith 4CL_PINTA P41636 4-coumarate--coa ligase (ec 6.2.1.12)(537 aa), fasta scores, opt: 622. E(): 1e-31, (30.0% identity in 514 aa overlap); contains PS00455 Putative AMP-binding domain signature; also si (fadD4) {Mycobacterium tuberculosis H37Rv (lab strain)}
214Rv0215c, (MTCY08D5.10c), len: 357 aa, similar eg toACDB_BACSU P45857 acyl-coa dehydrogenase (ec 1.3.99.-). (379 aa), fasta scores, opt: 812, E(): 0, (39.5% identity in 354 aa overlap) (fadE3) {Mycobacterium tuberculosis H37Rv (lab strain)}
215Rv0216hypothetical protein Rv0216 {Mycobacterium tuberculosis H37Rv (lab strain)}
216Rv0217c, (MTCY08D5.12c), len: 302 aa, similarity with eg EST_ACICA P18773 esterase (ec 3.1.1.-) (303 aa), fasta scores, opt: 320, E(): 3.2e-13, (29.2% identity in 274 aaoverlap) (lipW) {Mycobacterium tuberculosis H37Rv (lab strain)}
217Rv0218hypothetical protein Rv0218 {Mycobacterium tuberculosis H37Rv (lab strain)}
218Rv0219hypothetical protein Rv0219 {Mycobacterium tuberculosis H37Rv (lab strain)}
219Rv0220, (MTCY08D5.15),len: 403, probable esterase similar to M. tuberculosis Q50681 hypothetical 46.7 kDa protein (431 aa), fasta scores, opt: 841, E(): 0, (38.2% identity in 408 aa overlap); similar to several Mycobacterium tuberculosis hypothetical proteins: (lipC) {Mycobacterium tuberculosis H37Rv (lab strain)}
220Rv0221hypothetical protein Rv0221 {Mycobacterium tuberculosis H37Rv (lab strain)}
221Rv0222, (MTCY08D5.17), echA1, enoyl coa hydratase homologue, len: 262 aa, similar to eg CAID_ECOLI P31551 carnitine racemase (ec 5.-.-.-) (297 aa), fasta scores, opt: 525, E():3.4e-26, (41.8% identity in 249 aa overlap), and MTV023_23 (echA1) {Mycobacterium tuberculosis H37Rv (lab strain)}
222Rv0223chypothetical protein Rv0223c {Mycobacterium tuberculosis H37Rv (lab strain)}
223Rv0224chypothetical protein Rv0224c {Mycobacterium tuberculosis H37Rv (lab strain)}
224Rv0225hypothetical protein Rv0225 {Mycobacterium tuberculosis H37Rv (lab strain)}
225Rv0226chypothetical protein Rv0226c {Mycobacterium tuberculosis H37Rv (lab strain)}
226Rv0227chypothetical protein Rv0227c {Mycobacterium tuberculosis H37Rv (lab strain)}
227Rv0228hypothetical protein Rv0228 {Mycobacterium tuberculosis H37Rv (lab strain)}
228Rv0229chypothetical protein Rv0229c {Mycobacterium tuberculosis H37Rv (lab strain)}
229Rv0230chypothetical protein Rv0230c {Mycobacterium tuberculosis H37Rv (lab strain)}
230Rv0231, (MTCY08D5.27), len: 568 aa, fadE4, probableACYL-COA DEHYDROGENASE, similar to Archaeoglobus fulgidus sp|O29752|O29752 ACYL-COA DEHYDROGENASE (ACD-3). (576 aa),opt: 1788 z-score: 2195.4 E(): 0; 51.0% identity in 577 aaoverlap, also to ACDB_BACSU P45857 a (fadE4) {Mycobacterium tuberculosis H37Rv (lab strain)}
231Rv0232hypothetical protein Rv0232 {Mycobacterium tuberculosis H37Rv (lab strain)}
232Rv0233, (MTCY08D5.29), len: 314 aa, probable ribonucleoside-diphosphate reductase similar to eg RIR2_SCHPO P36603 ribonucleoside-diphosphate reductase (391 aa), fasta scores, opt: 168, E(): 0.00018, (26.1% identity in 199 aa overlap) (nrdB) {Mycobacterium tuberculosis H37Rv (lab strain)}
233Rv0234c, (MTCY08D5.30c), gabD2, aldehyde dehydrogenase, len: 511 aa but could start differently by homology, similarto eg GABD_ECOLI P25526 succinate-semialdehyde dehydrogenase (482 aa), fasta scores, opt: 929, E(): 0, (36.5% identityin 452 aa overlap), highly s (gabD2) {Mycobacterium tuberculosis H37Rv (lab strain)}
234Rv0235chypothetical protein Rv0235c {Mycobacterium tuberculosis H37Rv (lab strain)}
235Rv0236chypothetical protein Rv0236c {Mycobacterium tuberculosis H37Rv (lab strain)}
236Rv0237, (MTV034.03), len: 388. Lipoprotein similar to ALTEROMONAS SP. BETA-HEXOSAMINIDASE A PRECURSOR (598 aa)and Synechocystis sp. PCC6803 sptr|P74340|P74340 BETA-GLUCOSIDASE (538 aa). Contains signal sequence and appropriatelypositioned PS00013 Prokaryotic me (lpqI) {Mycobacterium tuberculosis H37Rv (lab strain)}
237Rv0238hypothetical protein Rv0238 {Mycobacterium tuberculosis H37Rv (lab strain)}
238Rv0239hypothetical protein Rv0239 {Mycobacterium tuberculosis H37Rv (lab strain)}
239Rv0240hypothetical protein Rv0240 {Mycobacterium tuberculosis H37Rv (lab strain)}
240Rv0241chypothetical protein Rv0241c {Mycobacterium tuberculosis H37Rv (lab strain)}
241Rv0242c, (MTV034.08c), len: 454.fabG4, Probably 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE as C-terminal part highlysimilar to various FabG proteins e.g. U39441|VHU39441_2 (244 aa). Has N-terminal extension of 200 aa and C-terminal part contains PS00061 Short-ch (fabG4) {Mycobacterium tuberculosis H37Rv (lab strain)}
242Rv0243, (MTV034.09), len: 440. fadA2, but similar to MITOCHONDRIAL TRIFUNCTONAL ENZYME BETA SUBUNIT PRECURSOR(474 aa) with 3-KETOACYL-COA THIOLASE (EC 2.3.1.16), ACETYL-COA ACYLTRANSFERASE and BETA-KETOTHIOLASE activities (TP-BETA). Also very similar to Escheri (fadA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
243Rv0244c, (MTV034.10c), len: 611.fadE5, Possibly acyl-CoA dehydrogenase, highly similar to Mycobacterium tuberculosisMTV007.14 (609 aa) and to various other bacterial proteinsdescribed as putative acyl-CoA dehydrogenases e.g. Archaeoglobus fulgidus AE001025_6 (38 (fadE5) {Mycobacterium tuberculosis H37Rv (lab strain)}
244Rv0245hypothetical protein Rv0245 {Mycobacterium tuberculosis H37Rv (lab strain)}
245Rv0246hypothetical protein Rv0246 {Mycobacterium tuberculosis H37Rv (lab strain)}
246Rv0247chypothetical protein Rv0247c {Mycobacterium tuberculosis H37Rv (lab strain)}
247Rv0248chypothetical protein Rv0248c {Mycobacterium tuberculosis H37Rv (lab strain)}
248Rv0249chypothetical protein Rv0249c {Mycobacterium tuberculosis H37Rv (lab strain)}
249Rv0250chypothetical protein Rv0250c {Mycobacterium tuberculosis H37Rv (lab strain)}
250Rv0251c, (MTV034.17c), len: 159. hsp, possibly heat shock protein belonging to HSP20 family, some similarity to many eukaryotic proteins e.g. CHLAMYDOMONAS REINHARDTII P12811|HS2C_CHLRE. Also similar to Synechocystis sp. PCC6803 Spore protein sp21 (146 aa). FAST (hsp) {Mycobacterium tuberculosis H37Rv (lab strain)}
251Rv0252, (MTV034.18), nirB, len: 853. Probable nitrite reductase flavoprotein containing siroheme and a 2FE-2S iron-sulfur centre. Similar to many bacterial enzymes e.g. P08201|NIRB_ECOLI (847 aa). Contains PS00365 Nitrite and sulfite reductases iron-sulfur/siro (nirB) {Mycobacterium tuberculosis H37Rv (lab strain)}
252Rv0253, (MTV034.19), nirD, len: 118. Probable nitrite reductase small subunit, similar to several e.g. P23675|NIRD_ECOLI(108 aa). FASTA scores sp|P23675|NIRD_ECOLI NITRITE REDUCTASE (NAD(P)H) SMALL (108 aa) opt: 271 z-score: 359.1 E():1.7e-12; 41.9% identity in (nirD) {Mycobacterium tuberculosis H37Rv (lab strain)}
253Rv0254c, (MTV034.20), cobU, len: 174. Probable cobinamide kinase similar to many e.g. sp|Q05599|COBU_SALTY (181 aa). Contains PS00017 ATP/GTP-binding site motif A (P-loop). FASTA scores sp|Q05599|COBU_SALTY COBINAMIDE KINASE / COBINAMIDE PH (181 aa) opt: 308 z-s (cobU) {Mycobacterium tuberculosis H37Rv (lab strain)}
254Rv0255c, (MTV034.21c), cobQ, len: 494. Probable cobyric acid synthase similar to many e.g. RCBLUGNS_8 (483 aa)and P29932|COBQ_PSEDE (484 aa). FASTA scores Z46611|RCBLUGNS_8 R.capsulatus (483 aa) opt: 1239 z-score: 1509.0 E(): 0;47.1% identity in 493 aa overlap; (cobQ) {Mycobacterium tuberculosis H37Rv (lab strain)}
255Rv0256c, (MTV034.22c), len: 556. Member of the conserved M. tuberculosis PPE family of proteins similar to MTCY261.19 (473 aa) and MLCB2492.30 (572 aa). FASTA scores Z98756|MLCB2492_30 B249 (572 aa) opt: 1837 z-score: 1136.9 E(): 0; 62.9% identity in 461 aa over (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
256Rv0257chypothetical protein Rv0257c {Mycobacterium tuberculosis H37Rv (lab strain)}
257Rv0258chypothetical protein Rv0258c {Mycobacterium tuberculosis H37Rv (lab strain)}
258Rv0259chypothetical protein Rv0259c {Mycobacterium tuberculosis H37Rv (lab strain)}
259Rv0260chypothetical protein Rv0260c {Mycobacterium tuberculosis H37Rv (lab strain)}
260Rv0261c, (MTCY06A4.05c), len: 469 aa, similar to egNARK_ECOLI P10903 nitrite extrusion protein 1 (463 aa), fasta scores, opt: 755, E(): 0, (35.0% identity in 466 aa overlap) (narK3) {Mycobacterium tuberculosis H37Rv (lab strain)}
261Rv0262chypothetical protein Rv0262c {Mycobacterium tuberculosis H37Rv (lab strain)}
262Rv0263chypothetical protein Rv0263c {Mycobacterium tuberculosis H37Rv (lab strain)}
263Rv0264chypothetical protein Rv0264c {Mycobacterium tuberculosis H37Rv (lab strain)}
264Rv0265c, (MTCY06A4.09c), fecB2, iron transport protein, len: 330 aa, most similar to FECB_ECOLI P15028 iron(iii) dicitrate-binding periplasm (300 aa), fasta scores, opt:191, E(): 2.3e-05, (26.5% identity in 196 aa overlap). Alsosimilar to D90899_15 Synechocystis (fecB2) {Mycobacterium tuberculosis H37Rv (lab strain)}
265Rv0266chypothetical protein Rv0266c {Mycobacterium tuberculosis H37Rv (lab strain)}
266Rv0267, (MTCY06A4.11), len: 463 aa, similar to nitrite extrusion proteins eg NARU_ECOLI P37758 nitrite extrusion protein 2 (462 aa), fasta scores, opt: 630, E(): 4.4e-33, (38.9% identity in 463 aa overlap), and NARK_ECOLI P10903nitrite extrusion protein 1 (463 (narU) {Mycobacterium tuberculosis H37Rv (lab strain)}
267Rv0268chypothetical protein Rv0268c {Mycobacterium tuberculosis H37Rv (lab strain)}
268Rv0269chypothetical protein Rv0269c {Mycobacterium tuberculosis H37Rv (lab strain)}
269Rv0270, (MTCY06A4.14), len: 560 aa, probable fadD2 similar to eg LCFA_ECOLI P29212 long-chain-fatty-acid--coa ligase (561 aa), fasta scores, opt: 544, E(): 2.9e-26, (27.7% identity in 535 aa overlap); Also similar to MTCY493_2, MTCY8D5_9, MTCY6G11_8YDID_ECOLI, (fadD2) {Mycobacterium tuberculosis H37Rv (lab strain)}
270Rv0271c, (MTCY06A4.15c), len: 731 aa, fadA6, C-terminal half similar to eg ACDS_HUMAN P16219 acyl-coa dehydrogenase, short-chain (412 aa), fasta scores, opt: 339, E(): 1.3e-13, (28.1% identity in 288 aa overlap) (fadE6) {Mycobacterium tuberculosis H37Rv (lab strain)}
271Rv0272chypothetical protein Rv0272c {Mycobacterium tuberculosis H37Rv (lab strain)}
272Rv0273chypothetical protein Rv0273c {Mycobacterium tuberculosis H37Rv (lab strain)}
273Rv0274hypothetical protein Rv0274 {Mycobacterium tuberculosis H37Rv (lab strain)}
274Rv0275c, (MTV035.03c), len: 241. fadD27, similar togp|AL022004|MTV043_17 Mycobacterium tuberculosis seque (213aa), FASTA scores: opt: 230 z-score: 266.0 E(): 2.7e-07; 32.6% identity in 190 aa overlap.TBparse score is 0.896 (fadD27) {Mycobacterium tuberculosis H37Rv (lab strain)}
275Rv0276hypothetical protein Rv0276 {Mycobacterium tuberculosis H37Rv (lab strain)}
276Rv0277chypothetical protein Rv0277c {Mycobacterium tuberculosis H37Rv (lab strain)}
277Rv0278c, (MTV035.06c), len: 957. Member of M. tuberculosis Gly-, Ala-rich PGRS subfamily of PE protein family.Similar tomany others. Contains PS00583 pfkB family of carbohydrate kinases signature 1. FASTA scores: Z95890|MTCY28_25 (914 aa) opt: 3849 z-score: 2368 (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
278Rv0279c, (MTV035.07c), len: 837. Member of M. tuberculosis Gly-, Ala-rich PGRS subfamily of PE protein family.Similar to many others. FASTA scores: Z95890|MTCY28_25 Mycobacteriumtuberculosis cosmid (914 aa) opt: 2677 z-score:1625.3 E(): 0; 64.5% identity in 926 (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
279Rv0280, (MTV035.08), len: 536. Member of Mycobacterium tuberculosis PPE_family of hypothetical proteins. FASTAscores: Z80108|MTCY21B4_4 (539 aa) opt: 1131 z-score: 872.4E(): 0; 51.7% identity in 540 aa overlap. TBparse score is0.904 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
280Rv0281hypothetical protein Rv0281 {Mycobacterium tuberculosis H37Rv (lab strain)}
281Rv0282hypothetical protein Rv0282 {Mycobacterium tuberculosis H37Rv (lab strain)}
282Rv0283hypothetical protein Rv0283 {Mycobacterium tuberculosis H37Rv (lab strain)}
283Rv0284hypothetical protein Rv0284 {Mycobacterium tuberculosis H37Rv (lab strain)}
284Rv0285, (MTV035.13), len: 102. Unknown but member of large protein family found in Mycobacterium tuberculosis,PE family, containing MTV012_37 (105 aa), MTCY21B4.03 (102aa), etc. FASTA scores: gp|AL0212|MTV012_37 (105 aa) opt:497z-score: 571.1 E(): 2.6e-24; 80.4 (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
285Rv0286, (MTV035.14), len: 513. Member of large Gly-Ala-rich protein family, PPE family, found in mycobacteria.FASTA scores: AL0212|MTV012_32 Mycobacterium tuberculosissequenc (434 aa) opt: 958 z-score: 781.7 E(): 0; 43.5%identityin 522 aa overlap. TBparse score (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
286Rv0287hypothetical protein Rv0287 {Mycobacterium tuberculosis H37Rv (lab strain)}
287Rv0288hypothetical protein Rv0288 {Mycobacterium tuberculosis H37Rv (lab strain)}
288Rv0289hypothetical protein Rv0289 {Mycobacterium tuberculosis H37Rv (lab strain)}
289Rv0290hypothetical protein Rv0290 {Mycobacterium tuberculosis H37Rv (lab strain)}
290Rv0291hypothetical protein Rv0291 {Mycobacterium tuberculosis H37Rv (lab strain)}
291Rv0292hypothetical protein Rv0292 {Mycobacterium tuberculosis H37Rv (lab strain)}
292Rv0293chypothetical protein Rv0293c {Mycobacterium tuberculosis H37Rv (lab strain)}
293Rv0294hypothetical protein Rv0294 {Mycobacterium tuberculosis H37Rv (lab strain)}
294Rv0295chypothetical protein Rv0295c {Mycobacterium tuberculosis H37Rv (lab strain)}
295Rv0296c, (MTCY63.01c-MTV035.24c), len: 465, atsG, Function: unknown, but some similarity to aryl- and steryl-sulfatases. Contains sulfatases signature 1 (PS00523). FASTAresults:ARSB_FELCA P33727 arylsulfatase b precursor (ec 3.1.6.1) (535 aa) opt: 231; E(): 1.7e (atsG) {Mycobacterium tuberculosis H37Rv (lab strain)}
296Rv0297, (MTCY63.02), len: 591. Unknown Gly, Ala-rich protein belonging to the PGRS family (PE). Many relatives in M. tuberculosis. FASTA results: Y03A_MYCTU Q10637 hypothetical glycine-rich 49.6 kd pro (603 aa) opt: 1884; E(): 0; 53.7% identity in 635 aa overla (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
297Rv0298hypothetical protein Rv0298 {Mycobacterium tuberculosis H37Rv (lab strain)}
298Rv0299hypothetical protein Rv0299 {Mycobacterium tuberculosis H37Rv (lab strain)}
299Rv0300hypothetical protein Rv0300 {Mycobacterium tuberculosis H37Rv (lab strain)}
300Rv0301hypothetical protein Rv0301 {Mycobacterium tuberculosis H37Rv (lab strain)}
301Rv0302hypothetical protein Rv0302 {Mycobacterium tuberculosis H37Rv (lab strain)}
302Rv0303hypothetical protein Rv0303 {Mycobacterium tuberculosis H37Rv (lab strain)}
303Rv0304c, (MTCY63.9c), len: 2204 aa. Member of the Gly-, Ala-, Asn- rich family of M. tuberculosis proteins (PPE, MPTR), similar to gp|Z95324|MTY13E10_16 Mycobacterium tuberculosis cosmi (1443 aa); E(): 0; 50.6% identity in 1403 aa overlap. Y04H_MYCTU Q10778 hypo (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
304Rv0305c, (MTCY63.10c), len: 963 aa. Member of the Gly-, Ala-, Asn- rich family of M. tuberculosis proteins (PPE, MPTR), Function: unknown. FASTA results: Y04H_MYCTU Q10778 hypothetical 72.9 kd protein cy48.17 (734 aa) opt: 1340 z-score: 1225.9 E(): 0, 40.9% iden (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
305Rv0306hypothetical protein Rv0306 {Mycobacterium tuberculosis H37Rv (lab strain)}
306Rv0307chypothetical protein Rv0307c {Mycobacterium tuberculosis H37Rv (lab strain)}
307Rv0308hypothetical protein Rv0308 {Mycobacterium tuberculosis H37Rv (lab strain)}
308Rv0309hypothetical protein Rv0309 {Mycobacterium tuberculosis H37Rv (lab strain)}
309Rv0310chypothetical protein Rv0310c {Mycobacterium tuberculosis H37Rv (lab strain)}
310Rv0311hypothetical protein Rv0311 {Mycobacterium tuberculosis H37Rv (lab strain)}
311Rv0312hypothetical protein Rv0312 {Mycobacterium tuberculosis H37Rv (lab strain)}
312Rv0313hypothetical protein Rv0313 {Mycobacterium tuberculosis H37Rv (lab strain)}
313Rv0314chypothetical protein Rv0314c {Mycobacterium tuberculosis H37Rv (lab strain)}
314Rv0315hypothetical protein Rv0315 {Mycobacterium tuberculosis H37Rv (lab strain)}
315Rv0316hypothetical protein Rv0316 {Mycobacterium tuberculosis H37Rv (lab strain)}
316Rv0317c, (MTCY63.22c), len: 256. glpQ2, some similarity to glycerophosphoryl diester phosphodiesterase. Startuncertain, chosen by homology. FASTA results: UGPQ_ECOLI P10908 gl (247 aa) opt: 220; E(): 5.2e-07; 28.0% identity in250 aa overlap. TBparse score is 0.9 (glpQ2) {Mycobacterium tuberculosis H37Rv (lab strain)}
317Rv0318chypothetical protein Rv0318c {Mycobacterium tuberculosis H37Rv (lab strain)}
318Rv0319, (MTCY63.24), len: 222. Function: pcp, probable pyrrolidone-carboxylate peptidase (EC 3.4.19.3; pyroglutamyl-peptidase I). FASTA results: PCP_PSEFL P42673 pyrrolidone-carboxylate peptidase (ec (213 aa) initn: 386opt: 478; E(): 7.5e-25; 40.2% identity in (pcp) {Mycobacterium tuberculosis H37Rv (lab strain)}
319Rv0320hypothetical protein Rv0320 {Mycobacterium tuberculosis H37Rv (lab strain)}
320Rv0321, (MTCY63.26), len: 190. Function: dcd, probable deoxycytidine triphosphate deaminase. Contains PS00017 ATP/GTP-binding site motif A (P-loop). FASTA results: DCD_ECOLI P28248 opt: 408; E(): 2.7e-21; 43.1% identity in 188 aa overlap. TBparse score is 0.907 (dcd) {Mycobacterium tuberculosis H37Rv (lab strain)}
321Rv0322, (MTCY63.27), len: 443. Function: udg, probable UDP-glucose dehydrogenase, also similar to GDP-mannose 6-dehydrogenase. Contains PS00017 ATP/GTP-binding site motif A (P-loop)FASTA results: Q56812 UDP-GLUCOSE DEHYDROGENASE(445 aa) opt: 713; E(): 0; 41.9% (udgA) {Mycobacterium tuberculosis H37Rv (lab strain)}
322Rv0323chypothetical protein Rv0323c {Mycobacterium tuberculosis H37Rv (lab strain)}
323Rv0324hypothetical protein Rv0324 {Mycobacterium tuberculosis H37Rv (lab strain)}
324Rv0325hypothetical protein Rv0325 {Mycobacterium tuberculosis H37Rv (lab strain)}
325Rv0326hypothetical protein Rv0326 {Mycobacterium tuberculosis H37Rv (lab strain)}
326Rv0327chypothetical protein Rv0327c {Mycobacterium tuberculosis H37Rv (lab strain)}
327Rv0328hypothetical protein Rv0328 {Mycobacterium tuberculosis H37Rv (lab strain)}
328Rv0329chypothetical protein Rv0329c {Mycobacterium tuberculosis H37Rv (lab strain)}
329Rv0330chypothetical protein Rv0330c {Mycobacterium tuberculosis H37Rv (lab strain)}
330Rv0331hypothetical protein Rv0331 {Mycobacterium tuberculosis H37Rv (lab strain)}
331Rv0332hypothetical protein Rv0332 {Mycobacterium tuberculosis H37Rv (lab strain)}
332Rv0333hypothetical protein Rv0333 {Mycobacterium tuberculosis H37Rv (lab strain)}
333Rv0334, (MTCY279.01), len: 288. rfbA, glucose-1-phosphate thymidylyl-transferase highly similar to many eg. RBA1_ECOLI P37744 glucose-1-phosphate thymidylyltransferase (293 aa), fasta scores; opt: 1199 z-score: 1884.1 E(): 0, 62.0% identity in 284 aa overlap (rmlA) {Mycobacterium tuberculosis H37Rv (lab strain)}
334Rv0335c, (MTCY279.02c), len: 171. unknown, containsshort region of similarity to part of the unique N-terminusof the M. tuberculosis PGRS family of Glycine-rich proteinseg. Y03A_MYCTU Q10637 hypothetical glycine-rich 49.6 kd protein (603 aa), fasta scores; opt: (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
335Rv0336hypothetical protein Rv0336 {Mycobacterium tuberculosis H37Rv (lab strain)}
336Rv0337c, (MTCY279.04c), len: 429,aspC, aspartate aminotransferase, similar to many eg. TR:Q48143 (EMBL:U32823) aspartate aminotransferase (404 aa), fasta scores; opt: 1646 z-score: 2132.9 E(): 0, 57.2% identity in 404 aa overlap; also some similarity to M. tuber (aspC) {Mycobacterium tuberculosis H37Rv (lab strain)}
337Rv0338chypothetical protein Rv0338c {Mycobacterium tuberculosis H37Rv (lab strain)}
338Rv0339chypothetical protein Rv0339c {Mycobacterium tuberculosis H37Rv (lab strain)}
339Rv0340hypothetical protein Rv0340 {Mycobacterium tuberculosis H37Rv (lab strain)}
340Rv0341hypothetical protein Rv0341 {Mycobacterium tuberculosis H37Rv (lab strain)}
341Rv0342hypothetical protein Rv0342 {Mycobacterium tuberculosis H37Rv (lab strain)}
342Rv0343hypothetical protein Rv0343 {Mycobacterium tuberculosis H37Rv (lab strain)}
343Rv0344c, (MTCY13E10.04c), len: 186. Function: unknown but probable lipoprotein; has an appropriately positioned prokaryotic lipoprotein signature (PS00013) (lpqJ) {Mycobacterium tuberculosis H37Rv (lab strain)}
344Rv0345hypothetical protein Rv0345 {Mycobacterium tuberculosis H37Rv (lab strain)}
345Rv0346c, (MTCY13E10.06c), len: 487. aroP2, Function: integral membrane protein belonging to family grouping many amino acid permeases. Highly similar to M. leprae protein G467030 (B2126_F2_85) and MTCY261_22 sp|O33261|O33261 L-ASPARAGINE PERMEASE. (489 aa); 72.1 (aroP2) {Mycobacterium tuberculosis H37Rv (lab strain)}
346Rv0347hypothetical protein Rv0347 {Mycobacterium tuberculosis H37Rv (lab strain)}
347Rv0348hypothetical protein Rv0348 {Mycobacterium tuberculosis H37Rv (lab strain)}
348Rv0349hypothetical protein Rv0349 {Mycobacterium tuberculosis H37Rv (lab strain)}
349Rv0350, (MTCY13E10.10), len: 625. Function: DnaK, 70 kD heat shock protein. FASTA best: DNAK_MYCPA Q00488 (623aa) opt: 3678, E(): 0, (92.3% identity in 625 aa overlap),note that this sequence differs from DNAK_MYCTU P32723 (609 aa), due to a frameshift near the (dnaK) {Mycobacterium tuberculosis H37Rv (lab strain)}
350Rv0351, (MTCY13E10.11), len: 249. Function: GrpE protein, contains grpE protein signature (PS01071). Identicalto GRPE_MYCTU P32724 (grpE) {Mycobacterium tuberculosis H37Rv (lab strain)}
351Rv0352, (MTCY13E10.12), len: 395. Function: DnaJ, contains both DnaJ signatures (PS00636, PS00637). Differs from DNAJ_MYCTU P07881 due to a frameshift at the N-terminus (dnaJ) {Mycobacterium tuberculosis H37Rv (lab strain)}
352Rv0353, (MTCY13E10.13), len: 126. Function: HspR, probable heat shock regulatory protein. Highly similar to HspR of Streptomyces coelicolor that binds to three inverted repeats (IR1-IR3) in the promoter region of the dnaK operon. Has possible coiled coil region (hspR) {Mycobacterium tuberculosis H37Rv (lab strain)}
353Rv0354c, (MTCY13E10.14c), len: 141. Function: unknown, related to PPE family, possible continuation of ORF upstream, but no sequence error apparent. FASTA best:MTCY63_9 Mycobacterium tuberculosis cosmid Y63 (2411 aa); E(): 3.6e-11; 47.6% identity in 103 aa overl (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
354Rv0355c, (MTCY13E10.15c-MTCY13E10.16c-MTCY13E10.17c)len: 3300, : unknown, member of the M. tuberculosis PPE_family, this Gly-, Asn-rich protein is similarto gp|AL009198|MTV004_5 Mycobacterium tuberculosis sequen (3716 aa)FASTA scores: opt: 2906 z-score: 2500.3 E (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
355Rv0356chypothetical protein Rv0356c {Mycobacterium tuberculosis H37Rv (lab strain)}
356Rv0357c, (MTCY13E10.19c), len: 432. Function: probable PurA, highly similar to many bacterial adenylosuccinatesynthetases. FASTA best: PURA_ECOLI P12283 adenylosuccinatesynthetase (431 aa), E(): 0; Smith-Waterman score: 1488; (51.1% identity in 425 aa overlap) (purA) {Mycobacterium tuberculosis H37Rv (lab strain)}
357Rv0358hypothetical protein Rv0358 {Mycobacterium tuberculosis H37Rv (lab strain)}
358Rv0359hypothetical protein Rv0359 {Mycobacterium tuberculosis H37Rv (lab strain)}
359Rv0360chypothetical protein Rv0360c {Mycobacterium tuberculosis H37Rv (lab strain)}
360Rv0361hypothetical protein Rv0361 {Mycobacterium tuberculosis H37Rv (lab strain)}
361Rv0362, (MTCY13E10.24), len: 460. Function: unknownbut C-terminal region is highly similar to putative Mg2+ transporter, mgtE from Providencia stuarti. Extended hydrophobic segment spanning last 130 residues. FASTA best: G780283 MGTE E(): 0; (47.2% identity in (mgtE) {Mycobacterium tuberculosis H37Rv (lab strain)}
362Rv0363c, (MTCY13E10.25c), len: 344. Function: fba, Probable fructose bisphosphate aldolase, highly similar to fructose bisphosphate aldolase of Coryunebacterium glutamicum, and other bacteria. FASTA best: X17313, CGFDA_2 E(): 0,(74.6% identity in 343 aa overlap) (fba) {Mycobacterium tuberculosis H37Rv (lab strain)}
363Rv0364hypothetical protein Rv0364 {Mycobacterium tuberculosis H37Rv (lab strain)}
364Rv0365chypothetical protein Rv0365c {Mycobacterium tuberculosis H37Rv (lab strain)}
365Rv0366chypothetical protein Rv0366c {Mycobacterium tuberculosis H37Rv (lab strain)}
366Rv0367chypothetical protein Rv0367c {Mycobacterium tuberculosis H37Rv (lab strain)}
367Rv0368chypothetical protein Rv0368c {Mycobacterium tuberculosis H37Rv (lab strain)}
368Rv0369chypothetical protein Rv0369c {Mycobacterium tuberculosis H37Rv (lab strain)}
369Rv0370chypothetical protein Rv0370c {Mycobacterium tuberculosis H37Rv (lab strain)}
370Rv0371chypothetical protein Rv0371c {Mycobacterium tuberculosis H37Rv (lab strain)}
371Rv0372chypothetical protein Rv0372c {Mycobacterium tuberculosis H37Rv (lab strain)}
372Rv0373chypothetical protein Rv0373c {Mycobacterium tuberculosis H37Rv (lab strain)}
373Rv0374chypothetical protein Rv0374c {Mycobacterium tuberculosis H37Rv (lab strain)}
374Rv0375chypothetical protein Rv0375c {Mycobacterium tuberculosis H37Rv (lab strain)}
375Rv0376chypothetical protein Rv0376c {Mycobacterium tuberculosis H37Rv (lab strain)}
376Rv0377hypothetical protein Rv0377 {Mycobacterium tuberculosis H37Rv (lab strain)}
377Rv0378hypothetical protein Rv0378 {Mycobacterium tuberculosis H37Rv (lab strain)}
378Rv0379, (MTV036.14), len: 71. Possible protein tansport protein similar to many. FASTA scores sp|P27340|S61G_SULSO PROTEIN TRANSPORT PROTEIN SEC61 G (65 aa) opt: 79 z-score: 135.6 E(): 4.7. 30.3% identity in 66 aa overlap. Also, MTV036.14 is highly similar to h (sec) {Mycobacterium tuberculosis H37Rv (lab strain)}
379Rv0380chypothetical protein Rv0380c {Mycobacterium tuberculosis H37Rv (lab strain)}
380Rv0381chypothetical protein Rv0381c {Mycobacterium tuberculosis H37Rv (lab strain)}
381Rv0382c, (MTV036.17c), len: 179. Ump, probable uridine 5-monophosphate synthase, similar to many others e.g. AE000938_10. FASTA scores: gp|AE0009|AE000938_10 Methanobacterium thermoautotroph(180 aa) opt: 389 z-score: 499.0 E(): 2.7e-20. 40.7% identity in 172 aa (umpA) {Mycobacterium tuberculosis H37Rv (lab strain)}
382Rv0383chypothetical protein Rv0383c {Mycobacterium tuberculosis H37Rv (lab strain)}
383Rv0384c, (MTV036.19c), len: 848. clpB, Heat shock protein ATP-binding protein highly similar to many e.g. U43536. FASTA scores: gp|U43536|CGU43536_1 Corynebacterium glutamicum heat s hock protein (852 aa) opt: 4113 z-score: 3973.4 E(): 0. 74.5% identity in 846 a (clpB) {Mycobacterium tuberculosis H37Rv (lab strain)}
384Rv0385hypothetical protein Rv0385 {Mycobacterium tuberculosis H37Rv (lab strain)}
385Rv0386hypothetical protein Rv0386 {Mycobacterium tuberculosis H37Rv (lab strain)}
386Rv0387chypothetical protein Rv0387c {Mycobacterium tuberculosis H37Rv (lab strain)}
387Rv0388c, (MTV036.23c), len: 180. Unknown; belongs to the M. tuberculosis PPE family,highly similar to e.g. MTCY10G2_10 (391 aa) but much shorter. FASTA scores: gp|Z92539|MTCY10G2_10 Mycobacterium tuberculosis cosmi (391 aa). opt: 667 z-score: 770.2 E(): 0. 58.3% (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
388Rv0389, (MTCY04D9.01-MTV036.24), len: 419. purT, similar eg to PURT_ECOLI P33221 phosphoribosylglycinamide formyltransferase 2, (391 aa), fasta scores, opt: 481, E(): 1.3e-22, (40.1% identity in 379 aa overlap) (purT) {Mycobacterium tuberculosis H37Rv (lab strain)}
389Rv0390hypothetical protein Rv0390 {Mycobacterium tuberculosis H37Rv (lab strain)}
390Rv0391, (MTCY04D9.03), len: 406. metZ homologue, similar to eg METZ_PSEAE P55218 o-succinylhomoserine sulfhydrylase (403 aa), fasta scores, opt: 1175, E(): 0, (47.2% identity in 392 aa overlap) (metZ) {Mycobacterium tuberculosis H37Rv (lab strain)}
391Rv0392chypothetical protein Rv0392c {Mycobacterium tuberculosis H37Rv (lab strain)}
392Rv0393hypothetical protein Rv0393 {Mycobacterium tuberculosis H37Rv (lab strain)}
393Rv0394chypothetical protein Rv0394c {Mycobacterium tuberculosis H37Rv (lab strain)}
394Rv0395hypothetical protein Rv0395 {Mycobacterium tuberculosis H37Rv (lab strain)}
395Rv0396hypothetical protein Rv0396 {Mycobacterium tuberculosis H37Rv (lab strain)}
396Rv0397hypothetical protein Rv0397 {Mycobacterium tuberculosis H37Rv (lab strain)}
397Rv0398chypothetical protein Rv0398c {Mycobacterium tuberculosis H37Rv (lab strain)}
398Rv0399c, (MTCY04D9.11c), len: 409 aa, some similarity to penicillin binding proteins, eg DAC_STRSQ P15555 d-alanyl-d-alanine carboxypeptidase protein (406 aa), fasta scores, opt: 348, E(): 5.6e-16, (29.2% identity in 301 aa overlap). Has possible N-terminal sign (lpqK) {Mycobacterium tuberculosis H37Rv (lab strain)}
399Rv0400c, (MTCY04D9.12c), len: 395 aa,fadE7, similarto acyl coA dehydrogenases, eg G624219 GLUTARYL-COA DEHYDROGENASE PRECURSOR. 6/96 (438 aa), fasta scores, opt: 1161, E(): 0, (48.1% identity in 391 aa overlap) (fadE7) {Mycobacterium tuberculosis H37Rv (lab strain)}
400Rv0401hypothetical protein Rv0401 {Mycobacterium tuberculosis H37Rv (lab strain)}
401Rv0402c, (MTCY04D9.15c), len: 958 aa, unknown, butsimilar to YV34_MYCTU Q11171 hypothetical 106.2 kd membraneprotein (968 aa), opt: 3551, E(): 0, (55.4% identity in 933aa overlap), YV34_MYCLE P54881 hypothetical 105.2 kd protein u1740v. (959 aa), opt: 3615, E(): (mmpL1) {Mycobacterium tuberculosis H37Rv (lab strain)}
402Rv0403c, (MTCY04D9.16c, unknown), len: 142 aa, similar to YV33_MYCLE P54880 hypothetical 16.9 kd protein u1740w (154 aa), fasta scores, opt: 458, E(): 1.6e-26, (46.9% identity in 143 aa overlap), YV33_MYCTU Q11170 hypothetical 15.9 kd protein cy20g9.3 (147 aa), (mmpS1) {Mycobacterium tuberculosis H37Rv (lab strain)}
403Rv0404, (MTCY04D9.17-MTCY22G10.00), len: 585. fadD30,Acyl-CoA Synthetase, similar to many e.g. MBU75685_1 Mycobacterium bovis sp|P71495|P71495 ACYL-COA SYNTHASE. Also similar to MASC_MYCLE P54200 masc protein from M. leprae U00010_6 (372 aa), fasta scores, opt: (fadD30) {Mycobacterium tuberculosis H37Rv (lab strain)}
404Rv0405, (MTCY22G10.01), len: 1402 , polyketide synthase similar to eg Y06K_MYCTU Q10977 probable polyketide synthase cy338.20 (1876 aa), fasta scores, opt: 2303, E(): 0, (38.7% identity in 1232 aa overlap); contains PS00606 Beta-ketoacyl synthases active site, (pks6) {Mycobacterium tuberculosis H37Rv (lab strain)}
405Rv0406chypothetical protein Rv0406c {Mycobacterium tuberculosis H37Rv (lab strain)}
406Rv0407hypothetical protein Rv0407 {Mycobacterium tuberculosis H37Rv (lab strain)}
407Rv0408, (MTCY22G10.04), len: 690, pta, similar to eg PTA_ECOLI P39184 phosphate acetyltransferase (713 aa), fasta scores, opt: 1303, E(): 0, (38.0% identity in 718 aa overlap) (pta) {Mycobacterium tuberculosis H37Rv (lab strain)}
408Rv0409, (MTCY22G10.05), len: 385, ackA, acetate kinase , similar to eg ACKA_BACSU P37877 acetate kinase (ec 2.7.2.1) (395 aa), fasta scores, opt: 974, E(): 0, (43.5% identity in 393 aa overlap), contains PS01075 Acetate and butyrate kinases family signature 1, (ackA) {Mycobacterium tuberculosis H37Rv (lab strain)}
409Rv0410c, (MTCY22G10.06c), len: 750 aa, protein kinase similar eg to PKNA_MYCLE P54743 protein kinase pkna. mycobacterium le (253 aa), fasta scores, opt: 291, E(): 3.1e-10, (33.2% identity in 202 aa overlap); contains PS00108 Serine/Threonine protein kinases acti (pknG) {Mycobacterium tuberculosis H37Rv (lab strain)}
410Rv0411c, (MTCY22G10.07c), len: 328 aa,glnH, similarto eg GLNH_BACST P27676 glutamine-binding protein precursor(262 aa), fasta scores, opt: 493, E(): 7.5e-22, (37.8% identity in 193 aa overlap), contains PS00013 Prokaryotic membranelipoprotein lipid attachment si (glnH) {Mycobacterium tuberculosis H37Rv (lab strain)}
411Rv0412chypothetical protein Rv0412c {Mycobacterium tuberculosis H37Rv (lab strain)}
412Rv0413, (MTCY22G10.10), len: 217, unknown, some similarity to eg MUTT_PROVU P32090 mutator mutt protein, (112 aa), fasta scores, opt: 151, E(): 0.0008, 40.7% identity in59 aa overlap) (mutT3) {Mycobacterium tuberculosis H37Rv (lab strain)}
413Rv0414c, (MTCY22G10.11c), len: 222, unknown, some similarity to THIE_ECOLI P30137 thie protein (211 aa), fastascores, opt: 275, E(): 7.8e-12, (37.8% identity in 196 aa overlap) (thiE) {Mycobacterium tuberculosis H37Rv (lab strain)}
414Rv0415hypothetical protein Rv0415 {Mycobacterium tuberculosis H37Rv (lab strain)}
415Rv0416hypothetical protein Rv0416 {Mycobacterium tuberculosis H37Rv (lab strain)}
416Rv0417, (MTCY22G10.14), len: 252, similar to thiG and C-terminal region of ruvB proteins eg THIG_ODOSI P49570 thig protein. odontella sinensis. (261 aa), fasta scores, opt: 568, E(): 1.9e-29, (45.8% identity in 253 aa overlap) orSYCSLRD_8 Synechocystis, Q55064 (thiG) {Mycobacterium tuberculosis H37Rv (lab strain)}
417Rv0418, (MTCCY22G10.15), len: 500 aa, lpqL, probable AMINOPEPTIDASE similar eg to SAPURCLUS_2 S;alboniger napH, pur7, Q53737 N-ACETYLPUROMYCIN N-ACETYLHYDROLASE precursor (485aa), fasta scores, opt: 924, E(): 0, (37.4% identity in 487aa overlap); contains PS000 (lpqL) {Mycobacterium tuberculosis H37Rv (lab strain)}
418Rv0419, (MTCY22G10.16), len: 498, unknown, containsPS00013 Prokaryotic membrane lipoprotein lipid attachment site, PS00142 Neutral zinc metallopeptidases, zinc-binding region signature (lpqM) {Mycobacterium tuberculosis H37Rv (lab strain)}
419Rv0420chypothetical protein Rv0420c {Mycobacterium tuberculosis H37Rv (lab strain)}
420Rv0421chypothetical protein Rv0421c {Mycobacterium tuberculosis H37Rv (lab strain)}
421Rv0422c, (MTCY22G10.19c), len: 265, thiD, probable PHOSPHOMETHYLPYRIMIDINE KINASE, similar to many, e.g. HIU32725_3 Haemophilus influenzae sp|P44697|THID_HAEIN PHOSPHOMETHYLPYRIMIDINE KINASE (E (269 aa); FASTA opt: 605 z-score:741.9 E(): 0; 42.1% identity in 259 (thiD) {Mycobacterium tuberculosis H37Rv (lab strain)}
422Rv0423c, (MTCY22G10.20c), thiC, len: 547 aa, similar to thiC proteins, eg SW:P45740 THIC_BACSU THIAMIN BIOSYNTHESIS PROTEIN protein (590 aa), fasta scores, opt: 2295, E(): 0, (65.2% identity in 580 aa overlap), SW:P30136 THIC_ECOLI thiC protein (631 aa), fasta s (thiC) {Mycobacterium tuberculosis H37Rv (lab strain)}
423Rv0424chypothetical protein Rv0424c {Mycobacterium tuberculosis H37Rv (lab strain)}
424Rv0425c, (MTCY22G10.22c), len: 1539 aa, ctpH, C-terminal region similar to eg Y05Q_MYCTU Q10900 putative cation-transporting atpase c (855 aa), fasta scores, opt: 770, E(): 5.3e-32, (44.9% identity in 820 aa overlap). Also similar to AE000873_1 Methanobacterium (ctpH) {Mycobacterium tuberculosis H37Rv (lab strain)}
425Rv0426chypothetical protein Rv0426c {Mycobacterium tuberculosis H37Rv (lab strain)}
426Rv0427c, (MTCY22G10.24c), len: 291, xthA, similar to eg EX3_ECOLI P09030 exodeoxyribonuclease iii (268 aa), fasta scores, opt: 360, E(): 1.2e-17, (29.3% identity in 270 aa overlap) (xthA) {Mycobacterium tuberculosis H37Rv (lab strain)}
427Rv0428chypothetical protein Rv0428c {Mycobacterium tuberculosis H37Rv (lab strain)}
428Rv0429c, (MTCY22G10.26c), len: 197,def, deformylase, similar to eg DEF_ECOLI P27251 polypeptide deformylase (168 aa), fasta scores, opt: 179, E(): 1.8e-05, (34.6% identity in 162 aa overlap) (def) {Mycobacterium tuberculosis H37Rv (lab strain)}
429Rv0430hypothetical protein Rv0430 {Mycobacterium tuberculosis H37Rv (lab strain)}
430Rv0431hypothetical protein Rv0431 {Mycobacterium tuberculosis H37Rv (lab strain)}
431Rv0432, (MTCY22G10.29), len: 240 aa, similar to superoxide dismutase eg SODC_PHOLE P00446 superoxide dismutaseprecursor (cu-zn) (173 aa), fasta scores, opt: 214, E(): 5.2e-06, (36.5% identity in 181 aa overlap), contains PS00013Prokaryotic membrane lipoprotein (sodC) {Mycobacterium tuberculosis H37Rv (lab strain)}
432Rv0433hypothetical protein Rv0433 {Mycobacterium tuberculosis H37Rv (lab strain)}
433Rv0434hypothetical protein Rv0434 {Mycobacterium tuberculosis H37Rv (lab strain)}
434Rv0435chypothetical protein Rv0435c {Mycobacterium tuberculosis H37Rv (lab strain)}
435Rv0436c, (MTCY22G10.33c), len: 286. pssA, similarity to eg PSS_BACSU P39823 cdp-diacylglycerol--serine o-phosphatidyltransferase (177 aa), fasta scores, opt: 277, E(): 9.9e-12, (33.3% identity in 183 aa overlap); start uncertain, contains PS00379 CDP-alcohol pho (pssA) {Mycobacterium tuberculosis H37Rv (lab strain)}
436Rv0437c, (MTV037.01c), len: 231. Similar to AE000875_6 Methanobacterium thermoautotrop (223 aa) O27105 PHOSPHATIDYLSERINE DECARBOXYLASE, FASTA: E(): 9.5e-18, 42.0% identity in 176 aa overlap; and to several hypothetical bacterial proteins e.g. Neisseria gonorrho (psd) {Mycobacterium tuberculosis H37Rv (lab strain)}
437Rv0438c, (MTV037.02c), len: 405. moeA-2, probable molybdenum cofactor biosynthesis protein (moeA-2) similar tomany e.g. ANY10817_2 (429 aa) and to Mycobacterium tuberculosis MoeA; MTCI237.08 (426 aa). FASTA scores: Y10817|ANY10817_2 A.nicotinovorans moaA, moeA, (moaA3) {Mycobacterium tuberculosis H37Rv (lab strain)}
438Rv0439chypothetical protein Rv0439c {Mycobacterium tuberculosis H37Rv (lab strain)}
439Rv0440, (MTV037.04), len: 539. groEL2, identical toM. tuberculosis GroEL-2. Has PS00296 Chaperonins cpn60 signature. FASTA scores: sp|P06806|CH62_MYCTU 60 KD CHAPERONIN2(PROTEIN CPN60 (539 aa) opt: 3318 z-score: 3673.1 E(): 0; 100.0% identity in 539 aa overlap. (groEL2) {Mycobacterium tuberculosis H37Rv (lab strain)}
440Rv0441chypothetical protein Rv0441c {Mycobacterium tuberculosis H37Rv (lab strain)}
441Rv0442c, (MTV037.06c), len: 487. Unknown member of PPE family, nearly identical to hypothetical protein from Mycobacterium tuberculosis (strain Erdman) and to protein fragment from Mycobacterium bovis, AN5 S46909_1 (302 aa). FASTA scores: sp|P42611|YHS6_MYCTU HY (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
442Rv0443hypothetical protein Rv0443 {Mycobacterium tuberculosis H37Rv (lab strain)}
443Rv0444chypothetical protein Rv0444c {Mycobacterium tuberculosis H37Rv (lab strain)}
444Rv0445c, (MTV037.09c), len: 187. sigK, probable RNApolymerase sigma factor similar to several e.g. Rhodobactersphaeroides 2.4.1 transcription regulator (168 aa) and Bacillus subtilis RSU11283_1 (168 aa) RNA polymerase ECF-typesigma factor (sigma-W). FASTA scores (sigK) {Mycobacterium tuberculosis H37Rv (lab strain)}
445Rv0446chypothetical protein Rv0446c {Mycobacterium tuberculosis H37Rv (lab strain)}
446Rv0447c, (MTV037.11c), len: 427. Probable cyclopropane fatty acidsynthase similar to several eg. Helicobacter pylori |HPAE000557_9 (389 aa). Start uncertain. FASTA scores: X55704|PPLPD_3 P.putida LPD-3 (394 aa) opt: 556 z-score: 678.2 E(): 2.8e-30; 33.3% identit (ufaA1) {Mycobacterium tuberculosis H37Rv (lab strain)}
447Rv0448chypothetical protein Rv0448c {Mycobacterium tuberculosis H37Rv (lab strain)}
448Rv0449chypothetical protein Rv0449c {Mycobacterium tuberculosis H37Rv (lab strain)}
449Rv0450c, (MTV037.14c), len: 967. Unknown transmembrane protein equivalent to M. leprae U1740V (959 aa) and similar to many others in M. tuberculosis including MTCY98.08 (962 aa), MTCY20G9.34, etc. Contains PS00211 ABC transporters family signature. FASTA scores: (mmpL4) {Mycobacterium tuberculosis H37Rv (lab strain)}
450Rv0451c, (MTV037.15c), len: 140. Transmembrane protein equivalent to M. leprae protein U1740W P54880|YV33_MYCLE (154 aa)also similar to Mycobacterium tuberculosis MTCY04D9.16c (142 aa). FASTA scores: sp|P54880|YV33_MYCLE HYPOTHETICAL 16.9 KD PROTEIN U174 (154 aa (mmpS4) {Mycobacterium tuberculosis H37Rv (lab strain)}
451Rv0452hypothetical protein Rv0452 {Mycobacterium tuberculosis H37Rv (lab strain)}
452Rv0453, (MTV037.17), len: 518. Member of M. tuberculosis PPE_family similar to many others, e.g. MTV012_32 (434 aa). FASTA scores: AL0212|MTV012_32 (434 aa) opt: 882 z-score: 689.0 E(): 7e-31; 41.8% identity in 514 aa overlap. TBparse score is 0.922 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
453Rv0454hypothetical protein Rv0454 {Mycobacterium tuberculosis H37Rv (lab strain)}
454Rv0455chypothetical protein Rv0455c {Mycobacterium tuberculosis H37Rv (lab strain)}
455Rv0456c, (MTCI429A.02-MTV037.20c), len 304, echA2,Possible enoyl-coAhydratase, similar to other enoyl-coA hydratases eg. Q13011 PEROXISOMAL ENOYL-COA HYDRATASE-LIKE protein (328 aa), fasta scores; opt: 209 z-score: 251.8 E():5.3e-07, 31.7% identity in 142 aa ove (echA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
456Rv0457chypothetical protein Rv0457c {Mycobacterium tuberculosis H37Rv (lab strain)}
457Rv0458hypothetical protein Rv0458 {Mycobacterium tuberculosis H37Rv (lab strain)}
458Rv0459hypothetical protein Rv0459 {Mycobacterium tuberculosis H37Rv (lab strain)}
459Rv0460hypothetical protein Rv0460 {Mycobacterium tuberculosis H37Rv (lab strain)}
460Rv0461hypothetical protein Rv0461 {Mycobacterium tuberculosis H37Rv (lab strain)}
461Rv0462hypothetical protein Rv0462 {Mycobacterium tuberculosis H37Rv (lab strain)}
462Rv0463hypothetical protein Rv0463 {Mycobacterium tuberculosis H37Rv (lab strain)}
463Rv0464chypothetical protein Rv0464c {Mycobacterium tuberculosis H37Rv (lab strain)}
464Rv0465chypothetical protein Rv0465c {Mycobacterium tuberculosis H37Rv (lab strain)}
465Rv0466hypothetical protein Rv0466 {Mycobacterium tuberculosis H37Rv (lab strain)}
466Rv0467, (MTV038.11), len: 428, aceA, probable isocitrate lyase similar to many, closest to R.fascians RFISCILY_1 (429 aa). FASTA scores: Z29367|RFISCILY_1 (429 aa) opt:2359 z-score: 2856.2 E(): 0; 80.7% identity in 429 aa overlap. TBparse score is 0.860 (aceA) {Mycobacterium tuberculosis H37Rv (lab strain)}
467Rv0468, (MTV038.12), len: 286. fadB2, Probable 3-hydroxyacyl-CoA dehydrogenase similar to many, e.g. Bradyrhizobium japonicum BJU32229_1 (293 aa) beta-hydroxybutyryl coenzyme Adehydrogenase (HbdA). FASTA scores: U32229|BJU32229_1 (293aa) opt: 771 z-score: 939.6 (fadB2) {Mycobacterium tuberculosis H37Rv (lab strain)}
468Rv0469, (MTV038.13), len: 286. Probably involved inmycolic acid modification or synthesis very similar to mycobacterial methyl transferase CmaD MBU77466_1 (286 aa) andto MTCY20H10.26c (296 aa; highly similar to CFA1_MYCTU Q11195 cyclopropane-fatty-acyl-phosphol (umaA1) {Mycobacterium tuberculosis H37Rv (lab strain)}
469Rv0470c, (MTV038.14), len: 287. Highly similar to Mycobacterium tuberculosis cyclopropane mycolic acid synthase MTU27357_1 (287 aa) and related enzymes e.g. MTCY20H10.25c (287 aa). FASTA scores: U27357|MTU27357_1 Mycobacterium tuberculosis cyclop (287 aa) opt: 1 (umaA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
470Rv0471chypothetical protein Rv0471c {Mycobacterium tuberculosis H37Rv (lab strain)}
471Rv0472chypothetical protein Rv0472c {Mycobacterium tuberculosis H37Rv (lab strain)}
472Rv0473hypothetical protein Rv0473 {Mycobacterium tuberculosis H37Rv (lab strain)}
473Rv0474hypothetical protein Rv0474 {Mycobacterium tuberculosis H37Rv (lab strain)}
474Rv0475hypothetical protein Rv0475 {Mycobacterium tuberculosis H37Rv (lab strain)}
475Rv0476hypothetical protein Rv0476 {Mycobacterium tuberculosis H37Rv (lab strain)}
476Rv0477hypothetical protein Rv0477 {Mycobacterium tuberculosis H37Rv (lab strain)}
477Rv0478, (MTCY20G9.04), len: 224, deoC, deoxyribose-phosphate aldolase, similar to eg DEOC_BACSU P39121 (214 aa) FASTA scores, opt: 543, z-score: 602.0, E(): 1.4e-26, (45.9% identity in 209 aa overlap) (deoC) {Mycobacterium tuberculosis H37Rv (lab strain)}
478Rv0479chypothetical protein Rv0479c {Mycobacterium tuberculosis H37Rv (lab strain)}
479Rv0480chypothetical protein Rv0480c {Mycobacterium tuberculosis H37Rv (lab strain)}
480Rv0481chypothetical protein Rv0481c {Mycobacterium tuberculosis H37Rv (lab strain)}
481Rv0482, (MTCY20G9.08), len: 369, similar to eg MURB_ECOLI P08373, udp-n-acetylenolpyruvoylglucosamine reductase murB (342 aa) opt: 292, z-score: 338.7, E(): 6.3e-12, (33.5% identity in 355 aa overlap) (murB) {Mycobacterium tuberculosis H37Rv (lab strain)}
482Rv0483hypothetical protein Rv0483 {Mycobacterium tuberculosis H37Rv (lab strain)}
483Rv0484chypothetical protein Rv0484c {Mycobacterium tuberculosis H37Rv (lab strain)}
484Rv0485hypothetical protein Rv0485 {Mycobacterium tuberculosis H37Rv (lab strain)}
485Rv0486hypothetical protein Rv0486 {Mycobacterium tuberculosis H37Rv (lab strain)}
486Rv0487hypothetical protein Rv0487 {Mycobacterium tuberculosis H37Rv (lab strain)}
487Rv0488hypothetical protein Rv0488 {Mycobacterium tuberculosis H37Rv (lab strain)}
488Rv0489, (MTCY20G9.15), len: 249,gpm, phosphoglycerate mutase 1, similar to egPMG1_ECOLI P31217 (249 aa) FASTAscores, opt: 805 z-score: 943.7 E(): 0, (51.4% identity in245aa overlap); contains PS00175 Phosphoglycerate mutase family phosphohistidine signature, PS (gpm) {Mycobacterium tuberculosis H37Rv (lab strain)}
489Rv0490, (MTCY20G9.16), len: 410, senX3, two-component sensor protein to Y13627|MBY13627_1 Mycobacterium bovisBCG senX3, O07129 SENX3 (410 aa); E(): 0; 99.5% identity in 410 aa overlap, , also highly similar to U00018_36 Mycobacterium leprae cosmid B2168, sp|P54 (senX3) {Mycobacterium tuberculosis H37Rv (lab strain)}
490Rv0491, (MTCY20G9.17), len: 227, response regulatorprotein; identical to Y13628|MTY13628_5 Mycobacterium tuberculosis senX3, RGX3 (227 aa); 100.0% identity in 227 aa overlap, and to Y13627|MBY13627_3 Mycobacterium bovis BCG, REGX3 (227 aa). highly similar to U0 (regX3) {Mycobacterium tuberculosis H37Rv (lab strain)}
491Rv0492chypothetical protein Rv0492c {Mycobacterium tuberculosis H37Rv (lab strain)}
492Rv0493chypothetical protein Rv0493c {Mycobacterium tuberculosis H37Rv (lab strain)}
493Rv0494hypothetical protein Rv0494 {Mycobacterium tuberculosis H37Rv (lab strain)}
494Rv0495chypothetical protein Rv0495c {Mycobacterium tuberculosis H37Rv (lab strain)}
495Rv0496hypothetical protein Rv0496 {Mycobacterium tuberculosis H37Rv (lab strain)}
496Rv0497hypothetical protein Rv0497 {Mycobacterium tuberculosis H37Rv (lab strain)}
497Rv0498hypothetical protein Rv0498 {Mycobacterium tuberculosis H37Rv (lab strain)}
498Rv0499hypothetical protein Rv0499 {Mycobacterium tuberculosis H37Rv (lab strain)}
499Rv0500, (MTCY20G9.26), len: 295, PYRROLINE-5-CARBOXYLATE REDUCTASE, highly similar to U00018_26 Mycobacteriumleprae PROC_MYCLE P46725 pyrroline-5-carboxylate reductase(294 aa) opt: 1473, z-score: 1624.5, E(): 0, (82.4% identityin 295 aa overlap) (proC) {Mycobacterium tuberculosis H37Rv (lab strain)}
500Rv0501, (MTCY20G9.28), len: 376,galE1, possible udp-glucose 4-epimerase, highly similar to 2 M. leprae orfs, N-terminal region, Q49830 B2168_C1_174 FASTA scores, opt: 934, z-score: 1093.7, E(): 0, (89.6% identity in 164 aa overlap), C-terminal region, Q49813 B2 (galE1) {Mycobacterium tuberculosis H37Rv (lab strain)}
501Rv0502hypothetical protein Rv0502 {Mycobacterium tuberculosis H37Rv (lab strain)}
502Rv0503c, (MTCY20G9.30c, cma2 gene), len: 302, identical to U34637|MTU34637_1 Mycobacterium tuberculosis cyclopropane mycolic acid synthase2 (322 aa), but we have chosen a different initiation codon on the basis of homology. Alsosimilar to U00018_21 Mycobacterium (cmaA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
503Rv0504chypothetical protein Rv0504c {Mycobacterium tuberculosis H37Rv (lab strain)}
504Rv0505c, (MTCY20G9.32c), len: 373, probable PHOSPHOSERINE PHOSPHATASE (SERB), highly similar to U00018_19 Mycobacterium leprae Q49823 SERB (300 aa), FASTA scores, opt: 1570, z-score: 1642.6, E(): 0, (83.0% identity in 306 aa overlap), low similarity to SERB_ECOL (serB) {Mycobacterium tuberculosis H37Rv (lab strain)}
505Rv0506, (MTCY20G9.33), len: 147, unknown, similar to MLU15183_31 Mycobacterium leprae cosmid B174P54880|YV33_MYCLE (154 aa) FASTA scores, opt: 392, z-score: 494.6, E(): 1.3e-20, (43.7% identity in 151 aa overlap) , also similar to MTV040_5, MTCY4D9_16, MTV037_1 (mmpS2) {Mycobacterium tuberculosis H37Rv (lab strain)}
506Rv0507, (MTCY20G9.34), len: 968, unknown, similar to U15183|MLU15183_30 Mycobacterium leprae cosmid B174, YV34_MYCLE (959 aa) FASTA scores, opt: 3699 z-score: 4149.7 E(): 0, (58.3% identity in 940 aa overlap), also C-terminal half similar to Mycobacterium lepra (mmpL2) {Mycobacterium tuberculosis H37Rv (lab strain)}
507Rv0508hypothetical protein Rv0508 {Mycobacterium tuberculosis H37Rv (lab strain)}
508Rv0509, (MTCY20G9.36), len: 468,hemA, glutamyl-trna reductase, highly similar to HEM1_MYCLE P46724 (467 aa) FASTA scores, opt: 2377 z-score: 2571.8 E(): 0, (82.3% identity in463 aa overlap); contains PS00747 Glutamyl-tRNA reductase signature (hemA) {Mycobacterium tuberculosis H37Rv (lab strain)}
509Rv0510, (MTCY21C8.01-MTCY20G9.37), len: 309, hemC ,porphobilinogen deaminase, highly similar to U00018_17 Mycobacterium leprae Q49808 HEM3B (315 aa), fasta scores, opt:889, E(): 0, (88.1% identity in 159 aa overlap) (hemC) {Mycobacterium tuberculosis H37Rv (lab strain)}
510Rv0511, (MTCY21C8.02), len: 565. cysG, uroporphyrin-iii c-methyltransferase, highly similar to M. leprae G467061 CYSG (472 aa), fasta scores, opt: 1946, E(): 0, (83.3% identity in 472 aa overlap) (cysG) {Mycobacterium tuberculosis H37Rv (lab strain)}
511Rv0512, (MTCY20G10.02),len: 329, hemB, delta-aminolevulinic acid dehydratase, similar to many eg. HEM2_ECOLIP15002 delta-aminolevulinic acid dehydratase (323 aa), fasta scores; opt: 942 z-score: 970.0 E(): 0, 47.6% identity in317 aa overlap. Also highly similar (hemB) {Mycobacterium tuberculosis H37Rv (lab strain)}
512Rv0513hypothetical protein Rv0513 {Mycobacterium tuberculosis H37Rv (lab strain)}
513Rv0514hypothetical protein Rv0514 {Mycobacterium tuberculosis H37Rv (lab strain)}
514Rv0515hypothetical protein Rv0515 {Mycobacterium tuberculosis H37Rv (lab strain)}
515Rv0516chypothetical protein Rv0516c {Mycobacterium tuberculosis H37Rv (lab strain)}
516Rv0517hypothetical protein Rv0517 {Mycobacterium tuberculosis H37Rv (lab strain)}
517Rv0518hypothetical protein Rv0518 {Mycobacterium tuberculosis H37Rv (lab strain)}
518Rv0519chypothetical protein Rv0519c {Mycobacterium tuberculosis H37Rv (lab strain)}
519Rv0520hypothetical protein Rv0520 {Mycobacterium tuberculosis H37Rv (lab strain)}
520Rv0521chypothetical protein Rv0521c {Mycobacterium tuberculosis H37Rv (lab strain)}
521Rv0523chypothetical protein Rv0523c {Mycobacterium tuberculosis H37Rv (lab strain)}
522Rv0524, (MTCY25D10.03), len: 462, hemL, highly similar to GSA_MYCLE P46716 glutamate-1-semialdehyde 2,1-aminomutase (EC 5.4.3.8) (GSA)(446 aa), fasta scores, opt: 1532 z-score: 1581.4 E(): 0, (82.6% identity in 460 aa overlap); contains PS00600 Aminotransferase (hemL) {Mycobacterium tuberculosis H37Rv (lab strain)}
523Rv0525hypothetical protein Rv0525 {Mycobacterium tuberculosis H37Rv (lab strain)}
524Rv0526hypothetical protein Rv0526 {Mycobacterium tuberculosis H37Rv (lab strain)}
525Rv0527, (MTCY25D10.06), len: 259, ccsA, similar to CCDA_BACSU P45706 cytochrome c-type biogenesis protein (235 aa) opt: 307 z-score: 356.5 E(): 7.4e-13 (30.4% identity in 237aa overlap), highly similar to M. leprae Q49810 Q49810 B2168_C1_192 (262 aa), fasta sco (ccsA) {Mycobacterium tuberculosis H37Rv (lab strain)}
526Rv0528hypothetical protein Rv0528 {Mycobacterium tuberculosis H37Rv (lab strain)}
527Rv0529, (MTCY25D10.08), len: 324 aa, ccsB, similar to cytochrome c-type biogenesis proteins eg YCF5_CHLRE P48269 probable cytochrome c biogenesis protein (353 aa), fastascores,opt: 449 z-score: 549.6 E(): 1.3e-23 (34.4% identityin 247 aa overlap), highly simila (ccsB) {Mycobacterium tuberculosis H37Rv (lab strain)}
528Rv0530hypothetical protein Rv0530 {Mycobacterium tuberculosis H37Rv (lab strain)}
529Rv0531hypothetical protein Rv0531 {Mycobacterium tuberculosis H37Rv (lab strain)}
530Rv0532, (MTCY25D10.11), len: 594 aa, member of the M. tuberculosis PGRS family, similar to eg Y0DP_MYCTU Q50615 hypothetical glycine-rich 40.8 kd protein (498 aa) opt: 1703 z-score: 1219.4 E(): 0, (58.2% identity in 536 aa overlap) (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
531Rv0533c, (MTCY25D10.12c), len: 335, fabH, similar to FABH. STREPTOMYCES GLAUCESCENS Q54206 (333 aa) opt: 1109 z-score: 1217.5 E(): 0, (51.4% identity in 333 aa overlap),also FABH_ECOLI P24249 3-oxoacyl-[acyl-carrier-protein] synthase III (EC 2.3.1.41) (317 aa), (fabH) {Mycobacterium tuberculosis H37Rv (lab strain)}
532Rv0534c, (MTCY25D10.13c), len: 292, menA, similar to eg MENA_ECOLI P32166 1,4-dihydroxy-2-naphthoate octaprenyl (308 aa) opt: 495 z-score: 579.2 E(): 2.9e-25, (36.3% identity in 289 aa overlap) (menA) {Mycobacterium tuberculosis H37Rv (lab strain)}
533Rv0535, (MTCY25D10.14c), len: 264 aa, similar to PNP/MTAP FAMILY 2 OF PHOSPHORYLASES, similar to eg Y060_METJAQ60367 hypothetical protein mj0060 (252 aa) fasta scores, opt: 490 z-score: 570.7 E(): 9e-25, (35.0% identity in 254 aa overlap) (pnp) {Mycobacterium tuberculosis H37Rv (lab strain)}
534Rv0536, (MTCY25D10.15), len: 346 aa,galE2, similarto GALE_METJA Q57664 putative udp-glucose 4-epimerase (305aa), fasta scores, opt: 300 z-score: 350.7 E(): 1.6e-12, (30.9% identity in 343 aa overlap) (galE2) {Mycobacterium tuberculosis H37Rv (lab strain)}
535Rv0537chypothetical protein Rv0537c {Mycobacterium tuberculosis H37Rv (lab strain)}
536Rv0538hypothetical protein Rv0538 {Mycobacterium tuberculosis H37Rv (lab strain)}
537Rv0539hypothetical protein Rv0539 {Mycobacterium tuberculosis H37Rv (lab strain)}
538Rv0540hypothetical protein Rv0540 {Mycobacterium tuberculosis H37Rv (lab strain)}
539Rv0541chypothetical protein Rv0541c {Mycobacterium tuberculosis H37Rv (lab strain)}
540Rv0542c, (MTCY25D10.21c), len: 362, possible menE,highly similar to M. leprae Q50170 XCLB (352 aa), fasta scores, opt: 1815 z-score: 2003.1 E(): 0, (78.9% identity in 351 aa overlap), similar to MENE_HAEIN P44565 o-succinylbenzoic acid--coa ligase (452 aa)opt: 3 (menE) {Mycobacterium tuberculosis H37Rv (lab strain)}
541Rv0543chypothetical protein Rv0543c {Mycobacterium tuberculosis H37Rv (lab strain)}
542Rv0544chypothetical protein Rv0544c {Mycobacterium tuberculosis H37Rv (lab strain)}
543Rv0545c, (MTCY25D10.24c), len: 417 aa, similar to LOW-AFFINITY INORGANIC phosphate transporters eg PITA_ECOLI P37308 low-affinity inorganic phosphate transporter (499 aa), fasta scores, opt: 304 z-score: 303.3 E(): 6.9e-10, (32.5% identity in 234 aa overlap); hi (pitA) {Mycobacterium tuberculosis H37Rv (lab strain)}
544Rv0546chypothetical protein Rv0546c {Mycobacterium tuberculosis H37Rv (lab strain)}
545Rv0547chypothetical protein Rv0547c {Mycobacterium tuberculosis H37Rv (lab strain)}
546Rv0548c, (MTCY25D10.27c), len: 314, menB, similar to MENB_ECOLI P27290 naphthoate synthase (ec 4.1.3.36) (285 aa) opt: 599 z-score: 713.9 E(): 9.3e-33, (48.1% identity in 285 aa overlap) (menB) {Mycobacterium tuberculosis H37Rv (lab strain)}
547Rv0549chypothetical protein Rv0549c {Mycobacterium tuberculosis H37Rv (lab strain)}
548Rv0550chypothetical protein Rv0550c {Mycobacterium tuberculosis H37Rv (lab strain)}
549Rv0551c, (MTCY25D10.30c), len: 571, Acyl-CoA Synthetase, fadD8, ligase, but other possible start sites downstream of this start, similar to eg LCFA_ECOLI P29212 long-chain-fatty-acid--coa ligase (561 aa) opt: 585 z-score: 659.8 E(): 9.5e-30, (28.7% identity in 5 (fadD8) {Mycobacterium tuberculosis H37Rv (lab strain)}
550Rv0552hypothetical protein Rv0552 {Mycobacterium tuberculosis H37Rv (lab strain)}
551Rv0553, (MTCY25D10.32), len: 326, similar to o-succinylbenzoate-coa synthase or possible muconate cycloisomerase, eg TCBD_PSESP P27099 chloromuconate cycloisomerase (370 aa) opt: 249 z-score: 284.4 E(): 7.8e-09, (32.7% identity in 199 aa overlap) (menC) {Mycobacterium tuberculosis H37Rv (lab strain)}
552Rv0554, (MTCY25D10.33), len: 262, bpoC, similar to BPA2_STRAU P29715 non-haem bromoperoxidase bpo-a2 (277 aa),fastascores, opt: 325 z-score: 401.4 E(): 2.3e-15, (29.5% identity in 268 aa overlap) (bpoC) {Mycobacterium tuberculosis H37Rv (lab strain)}
553Rv0555, (MTCY25D10.34), len: 554 aa, menD, similar to MEND_BACSU P23970 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-CARBOXYLATE SYNTHASE (548 aa), fasta scores, opt: 488 z-score: 509.3 E(): 2.3e-21, (34.3% identity in 545 aa overlap) (menD) {Mycobacterium tuberculosis H37Rv (lab strain)}
554Rv0556hypothetical protein Rv0556 {Mycobacterium tuberculosis H37Rv (lab strain)}
555Rv0557hypothetical protein Rv0557 {Mycobacterium tuberculosis H37Rv (lab strain)}
556Rv0558, (MTCY25D10.37), len: 234, UBIE FAMILY member, probable methyltransferase, similar to UBIQUINONE/MENAQUINONE BIOSYNTHESIS METHYL TRANSFERASE UBIE_ECOLI P27851 28.1 kd protein (251 aa), fasta scores, opt: 421 z-score: 514.1 E(): 1.2e-21, (43.2% identity i (ubiE) {Mycobacterium tuberculosis H37Rv (lab strain)}
557Rv0559chypothetical protein Rv0559c {Mycobacterium tuberculosis H37Rv (lab strain)}
558Rv0560chypothetical protein Rv0560c {Mycobacterium tuberculosis H37Rv (lab strain)}
559Rv0561chypothetical protein Rv0561c {Mycobacterium tuberculosis H37Rv (lab strain)}
560Rv0562, (MTCY25D10.41), len: 335,grcC1, similar toGRC3_BACSU P31114 probable heptaprenyl diphosphate syntetase (348aa), fasta scores, opt: 599 z-score: 684.4 E(): 4e-31, (33.2% identity in 307 aa overlap), contains PS00444 Polyprenylsynthetases signature 2; hig (grcC1) {Mycobacterium tuberculosis H37Rv (lab strain)}
561Rv0563, (MTV039.01-MTCY25D10.42), len: 242. htpX, alternative start 654006 Probable heat shock protein X (transmembrane), similar to many closest to Methanococcus jannaschii MJU67608_8 (284 aa). FASTA scores: U67608|MJU67608_8 (284 aa) opt: 660 z-score: 793.6 E (htpX) {Mycobacterium tuberculosis H37Rv (lab strain)}
562Rv0564c, (MTV039.02c), len: 341.gpdA1, Probable dehydrogenase similar to Mycobacterium tuberculosis MTCY349.05 (334 aa), probable glycerol-3-phosphate dehydrogenase, and many other glycerol-3-phosphate dehydrogenases. Contains PS00017ATP/GTP-binding site motif A (gpdA1) {Mycobacterium tuberculosis H37Rv (lab strain)}
563Rv0565chypothetical protein Rv0565c {Mycobacterium tuberculosis H37Rv (lab strain)}
564Rv0566chypothetical protein Rv0566c {Mycobacterium tuberculosis H37Rv (lab strain)}
565Rv0567hypothetical protein Rv0567 {Mycobacterium tuberculosis H37Rv (lab strain)}
566Rv0568hypothetical protein Rv0568 {Mycobacterium tuberculosis H37Rv (lab strain)}
567Rv0569hypothetical protein Rv0569 {Mycobacterium tuberculosis H37Rv (lab strain)}
568Rv0570, (MTV039.08), len: 692. Unknown but similar to ribonucleotide reductase, large subunits e.g. Archaeoglobus fulgidus AE000988_11 (752 aa) and (Thermoplasma acidophilum TAU73619_1 (857 aa). FASTA scores: AE0009|AE000988_1 (752 aa) opt: 2001 z-score: 2335.6 (nrdZ) {Mycobacterium tuberculosis H37Rv (lab strain)}
569Rv0571chypothetical protein Rv0571c {Mycobacterium tuberculosis H37Rv (lab strain)}
570Rv0572chypothetical protein Rv0572c {Mycobacterium tuberculosis H37Rv (lab strain)}
571Rv0573chypothetical protein Rv0573c {Mycobacterium tuberculosis H37Rv (lab strain)}
572Rv0574chypothetical protein Rv0574c {Mycobacterium tuberculosis H37Rv (lab strain)}
573Rv0575chypothetical protein Rv0575c {Mycobacterium tuberculosis H37Rv (lab strain)}
574Rv0576hypothetical protein Rv0576 {Mycobacterium tuberculosis H37Rv (lab strain)}
575Rv0577hypothetical protein Rv0577 {Mycobacterium tuberculosis H37Rv (lab strain)}
576Rv0578c, (MTV039.16c), len: 1306. Member of glycine-rich PGRS subfamily of the Mycobacterium tuberculosis conserved PE protein family. Similar to many other PGRS proteins e.g. MTCY493.04. Contains two PS00583 pfkB family of carbohydrate kinases signatures possib (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
577Rv0579hypothetical protein Rv0579 {Mycobacterium tuberculosis H37Rv (lab strain)}
578Rv0580chypothetical protein Rv0580c {Mycobacterium tuberculosis H37Rv (lab strain)}
579Rv0581hypothetical protein Rv0581 {Mycobacterium tuberculosis H37Rv (lab strain)}
580Rv0582hypothetical protein Rv0582 {Mycobacterium tuberculosis H37Rv (lab strain)}
581Rv0583c, (MTV039.21c), len: 228. Unknown but equivalent to Mycobacterium kansasii MK35 lipoprotein. Contains N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site.FASTA scores: U20446|MKU20446_1 (2 (lpqN) {Mycobacterium tuberculosis H37Rv (lab strain)}
582Rv0584hypothetical protein Rv0584 {Mycobacterium tuberculosis H37Rv (lab strain)}
583Rv0585chypothetical protein Rv0585c {Mycobacterium tuberculosis H37Rv (lab strain)}
584Rv0586hypothetical protein Rv0586 {Mycobacterium tuberculosis H37Rv (lab strain)}
585Rv0587hypothetical protein Rv0587 {Mycobacterium tuberculosis H37Rv (lab strain)}
586Rv0588hypothetical protein Rv0588 {Mycobacterium tuberculosis H37Rv (lab strain)}
587Rv0589, (MTCY19H5.33c), len: 404; mce2, highly similar to TR:P72013 M. tuberculosis Mcep protein (EM_BA:MTMCE X70901) (MTCI28.08), fasta scores; opt: 1324 z-score: 1780.7 E(): 0, 62.6% identity in 436 aa overlap. See Arruda et al, Science v261 p1454. Similar to (mce2) {Mycobacterium tuberculosis H37Rv (lab strain)}
588Rv0590hypothetical protein Rv0590 {Mycobacterium tuberculosis H37Rv (lab strain)}
589Rv0591hypothetical protein Rv0591 {Mycobacterium tuberculosis H37Rv (lab strain)}
590Rv0592hypothetical protein Rv0592 {Mycobacterium tuberculosis H37Rv (lab strain)}
591Rv0593, (MTCY19H5.29c), len: 402; , lprL, alternative start would give N-terminal signal sequence containing PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Strongly similar to M. tuberculosis protein MTCI28.13 (65.2% identity in 374 aa overlap) (lprL) {Mycobacterium tuberculosis H37Rv (lab strain)}
592Rv0594hypothetical protein Rv0594 {Mycobacterium tuberculosis H37Rv (lab strain)}
593Rv0595chypothetical protein Rv0595c {Mycobacterium tuberculosis H37Rv (lab strain)}
594Rv0596chypothetical protein Rv0596c {Mycobacterium tuberculosis H37Rv (lab strain)}
595Rv0597chypothetical protein Rv0597c {Mycobacterium tuberculosis H37Rv (lab strain)}
596Rv0598chypothetical protein Rv0598c {Mycobacterium tuberculosis H37Rv (lab strain)}
597Rv0599chypothetical protein Rv0599c {Mycobacterium tuberculosis H37Rv (lab strain)}
598Rv0600chypothetical protein Rv0600c {Mycobacterium tuberculosis H37Rv (lab strain)}
599Rv0601chypothetical protein Rv0601c {Mycobacterium tuberculosis H37Rv (lab strain)}
600Rv0602c, (MTCY19H5.20), len: 232, two-component response regulator, almost identical to EM_BA:MTU56083 U56083 Mycobacterium tuberculosis two component response regulator (tcrA) gene, TRQ50825, (234 aa) opt: 1528, E(): 0, (97.9% identity in 234 aa overlap). Also (tcrA) {Mycobacterium tuberculosis H37Rv (lab strain)}
601Rv0603hypothetical protein Rv0603 {Mycobacterium tuberculosis H37Rv (lab strain)}
602Rv0604, (MTCY19H5.18c), len: 316; unknown, similar to MTV012_13, opt: 1153 z-score: 1323.0 E(): 0; 53.2% identity in 312 aa overlap.Contains probable N-terminal signal sequence and PS00013 Prokaryotic membrane lipoprotein lipid attachment site (lpqO) {Mycobacterium tuberculosis H37Rv (lab strain)}
603Rv0605hypothetical protein Rv0605 {Mycobacterium tuberculosis H37Rv (lab strain)}
604Rv0606hypothetical protein Rv0606 {Mycobacterium tuberculosis H37Rv (lab strain)}
605Rv0607hypothetical protein Rv0607 {Mycobacterium tuberculosis H37Rv (lab strain)}
606Rv0608hypothetical protein Rv0608 {Mycobacterium tuberculosis H37Rv (lab strain)}
607Rv0609hypothetical protein Rv0609 {Mycobacterium tuberculosis H37Rv (lab strain)}
608Rv0610chypothetical protein Rv0610c {Mycobacterium tuberculosis H37Rv (lab strain)}
609Rv0611chypothetical protein Rv0611c {Mycobacterium tuberculosis H37Rv (lab strain)}
610Rv0612hypothetical protein Rv0612 {Mycobacterium tuberculosis H37Rv (lab strain)}
611Rv0613chypothetical protein Rv0613c {Mycobacterium tuberculosis H37Rv (lab strain)}
612Rv0614hypothetical protein Rv0614 {Mycobacterium tuberculosis H37Rv (lab strain)}
613Rv0615hypothetical protein Rv0615 {Mycobacterium tuberculosis H37Rv (lab strain)}
614Rv0616chypothetical protein Rv0616c {Mycobacterium tuberculosis H37Rv (lab strain)}
615Rv0617hypothetical protein Rv0617 {Mycobacterium tuberculosis H37Rv (lab strain)}
616Rv0618, (MTCY19H5.03c), len: 231, galU1, galactose-1-phosphate uridylyltransferase, probable partial CDS, highly similar to N-terminal half of galT eg GAL7_STRLI P13212 galactose-1-phosphate uridylyltransferase (354 aa), fastascores, opt: 296 z-score: 333.9 E() (galT) {Mycobacterium tuberculosis H37Rv (lab strain)}
617Rv0619Protein sequence is in conflict with the conceptual translation; Rv0619, (MTCY19H5.02c,len: 181, galTa, galactose-1-phosphate uridylyltransferase, probable partial CDS, highly similar to C-terminal half of galT eg GAL7_STRLI P13212 galactose-1-phosphate u (galT) {Mycobacterium tuberculosis H37Rv (lab strain)}
618Rv0620, (MTCY19H5.01c-MTCY20H10.01), len: 363 aa; galK, Galactokinases,similar to eg GAL1_ECOLI P06976 galactokinase (ec 2.7.1.6) (381 aa), fasta scores, opt: 669, E(): 0, (35.9% identity in 365 aa overlap); contains PS00106 Galactokinase signature and PS00560 (galK) {Mycobacterium tuberculosis H37Rv (lab strain)}
619Rv0621hypothetical protein Rv0621 {Mycobacterium tuberculosis H37Rv (lab strain)}
620Rv0622hypothetical protein Rv0622 {Mycobacterium tuberculosis H37Rv (lab strain)}
621Rv0623hypothetical protein Rv0623 {Mycobacterium tuberculosis H37Rv (lab strain)}
622Rv0624hypothetical protein Rv0624 {Mycobacterium tuberculosis H37Rv (lab strain)}
623Rv0625chypothetical protein Rv0625c {Mycobacterium tuberculosis H37Rv (lab strain)}
624Rv0626hypothetical protein Rv0626 {Mycobacterium tuberculosis H37Rv (lab strain)}
625Rv0627hypothetical protein Rv0627 {Mycobacterium tuberculosis H37Rv (lab strain)}
626Rv0628chypothetical protein Rv0628c {Mycobacterium tuberculosis H37Rv (lab strain)}
627Rv0629c, (MTCY20H10.10c), len: 575, recD similar toexonucleases eg EX5A_ECOLI P04993 exodeoxyribonuclease v 67kd polypeptide (EC 3.1.11.5) (EXONUCLEASE V ALPHA CHAIN).(608 aa), fasta scores, opt: 512, E(): 1.9e-24, (36.9% identity in 582 aa overlap); contains PS (recD) {Mycobacterium tuberculosis H37Rv (lab strain)}
628Rv0630c, (MTCY20H10.11c), len: 1094, recB, similar to EX5B_ECOLI P08394 exodeoxyribonuclease v 135 kd polypeptide (EC 3.1.11.5) (EXONUCLEASE V BETA CHAIN) (1180 aa), fasta scores, opt: 289, E(): 4.3e-11, (29.5% identity in 1059 aa overlap); contains PS00017 ATP/ (recB) {Mycobacterium tuberculosis H37Rv (lab strain)}
629Rv0631c, (MTCY20H10.12c), len: 1097, recC similar to eg EX5C_ECOLI P07648 exodeoxyribonuclease v 125 kd polypeptide (EC 3.1.11.5) (EXONUCLEASE V GAMMA CHAIN). (1122 aa), fasta scores, opt: 954, E(): 0, (29.2% identity in 1109 aa overlap) (recC) {Mycobacterium tuberculosis H37Rv (lab strain)}
630Rv0632c, (MTCY20H10.13c), len: 231 aa,echA3, almost identical to the MTU88877_1 enoyl-coA hydratase of Mycobacteriumtuberculosis field isolate NTI64719 (92.4% identity in 184aa overlap), Also similar to eg ECHH_RHOCA P24162 enoyl-coa hydratase homolog and others (echA3) {Mycobacterium tuberculosis H37Rv (lab strain)}
631Rv0633chypothetical protein Rv0633c {Mycobacterium tuberculosis H37Rv (lab strain)}
632Rv0634chypothetical protein Rv0634c {Mycobacterium tuberculosis H37Rv (lab strain)}
633Rv0635hypothetical protein Rv0635 {Mycobacterium tuberculosis H37Rv (lab strain)}
634Rv0636hypothetical protein Rv0636 {Mycobacterium tuberculosis H37Rv (lab strain)}
635Rv0637hypothetical protein Rv0637 {Mycobacterium tuberculosis H37Rv (lab strain)}
636Rv0638, (MTCY20H10.19), len: 161, possible secE, similar at C-terminal half to eg SGNUSG_2 S;griseus nusG, rplKAJL gene cluster, SECE_STRGR PREPROTEIN TRANSLOCASE, opt:220 z-score: 244.0 E(): 4.6e-06, 35.4% identity in 96 aaoverlap; also similar to SECE_ECOLI P (secE) {Mycobacterium tuberculosis H37Rv (lab strain)}
637Rv0639, (MTCY20H10.20), len: 238 , nusG, similar toeg NUSG_STRGR P36260 transcription antitermination protein(294 aa), fasta scores, opt: 845, E(): 0, (55.4% identity in233 aa overlap), note shorter at the N-terminus than othernusG; contains PS01014 Transcripti (nusG) {Mycobacterium tuberculosis H37Rv (lab strain)}
638Rv0640, (MTCY20H11.21), len: 142, rplK, highly similar to eg RL11_STRCO P48954 50s ribosomal protein l11 (144aa), fasta scores, opt: 763, E(): 0, (84.6% identity in 143 aa overlap); contains PS00359 Ribosomal protein L11 signature (rplK) {Mycobacterium tuberculosis H37Rv (lab strain)}
639Rv0641, (MTCY20H10.22), len: 235, rplA, highly similar eg to RL1_STRGR P36256 50s ribosomal protein l1 (240 aa), fasta scores, opt: 1081, E(): 0, (72.2% identity in 230 aa overlap) (rplA) {Mycobacterium tuberculosis H37Rv (lab strain)}
640Rv0642c, (MTCY20H10.23c), len: 301 aa, mma4, Methoxymycolic Acid Synthase 4almost identical to MTU66108_4 Mycobacterium tuberculosis P72028 METHOXY MYCOLIC ACID SYNTHASE4 (301 aa)(99.7% identity in 301 aa overlap) (mmaA4) {Mycobacterium tuberculosis H37Rv (lab strain)}
641Rv0643c, (MTCY20H10.24c), len: 293, Methoxymycolic Acid Synthase 3, identical to MTU66108_3 Mycobacterium tuberculosis sp|P72027|P72027 METHOXY MYCOLIC ACID SYNTHASE 3.(293 aa); 100.0% identity in 293 aa overlap (mmaA3) {Mycobacterium tuberculosis H37Rv (lab strain)}
642Rv0644c, (MTCY20H10.25c), len: 287 aa, Methoxymycolic Acid Synthase 2, identical (but shorter) to MTU66108_2 Mycobacterium tuberculosis P72026 METHOXY MYCOLIC ACID SYNTHASE 2 (317 aa), (100.0% identity in 287 aa overlap) note that alternative start is at positio (mmaA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
643Rv0645c, (MTCY20H10.26c), len: 286 aa, Methoxymycolic Acid Synthase 1, almost identical to MTU66108_1 Mycobacterium tuberculosis methox (286 aa),P72025 METHOXY MYCOLIC ACID SYNTHASE 1, (97.9% identity in 286 aa overlap) (mmaA1) {Mycobacterium tuberculosis H37Rv (lab strain)}
644Rv0646c, (MTCY20H10.27c), len: 301 aa, similar to ACINETOBACTER CALCOACETICUS Q57172 HOMOLOGY TO HYDROLASES (312 aa), fasta scores, opt: 867, E(): 0, (50.2% identity in 279 aa overlap). Also similar to E. coli P77026 MACROLIDE 2-PHOSPHOTRANSFERASE II. (279 aa), (lipG) {Mycobacterium tuberculosis H37Rv (lab strain)}
645Rv0647chypothetical protein Rv0647c {Mycobacterium tuberculosis H37Rv (lab strain)}
646Rv0648hypothetical protein Rv0648 {Mycobacterium tuberculosis H37Rv (lab strain)}
647Rv0649, (MTCY20H10.30), len: 224, some similarity to FABD_MYCTU Q10501 probable malonyl coa-acyl carrier protein (302 aa), fasta scores, opt: 133, E(): 0.074, (31.3% identity in 147 aa overlap) (fadD37) {Mycobacterium tuberculosis H37Rv (lab strain)}
648Rv0650hypothetical protein Rv0650 {Mycobacterium tuberculosis H37Rv (lab strain)}
649Rv0651, (MTCY20H10.32), len: 178 aa, rplJ, similarto eg RL10_STRGR STREPTOMYCES GRISEUS, P36257 50s ribosomalprotein l10. (185 aa), fasta scores, opt: 633, E(): 0, (59.0% identity in 173 aa overlap) (rplJ) {Mycobacterium tuberculosis H37Rv (lab strain)}
650Rv0652, (MTCY20H10.33), len: 130, rplL, identical to RL7_MYCBO P37381 50s ribosomal protein l7/l12, M. bovis (130 aa) (rplL) {Mycobacterium tuberculosis H37Rv (lab strain)}
651Rv0653chypothetical protein Rv0653c {Mycobacterium tuberculosis H37Rv (lab strain)}
652Rv0654hypothetical protein Rv0654 {Mycobacterium tuberculosis H37Rv (lab strain)}
653Rv0655hypothetical protein Rv0655 {Mycobacterium tuberculosis H37Rv (lab strain)}
654Rv0656chypothetical protein Rv0656c {Mycobacterium tuberculosis H37Rv (lab strain)}
655Rv0657chypothetical protein Rv0657c {Mycobacterium tuberculosis H37Rv (lab strain)}
656Rv0658chypothetical protein Rv0658c {Mycobacterium tuberculosis H37Rv (lab strain)}
657Rv0659chypothetical protein Rv0659c {Mycobacterium tuberculosis H37Rv (lab strain)}
658Rv0660chypothetical protein Rv0660c {Mycobacterium tuberculosis H37Rv (lab strain)}
659Rv0661chypothetical protein Rv0661c {Mycobacterium tuberculosis H37Rv (lab strain)}
660Rv0662chypothetical protein Rv0662c {Mycobacterium tuberculosis H37Rv (lab strain)}
661Rv0663, (MTCI376.13c), len: 787, atsD, possible arylsulphatase, FASTA score: ARS_PSEAE P51691 arylsulfatase (ec 3.1.6.1) (532 aa) opt: 653 z-score: 729.3 E(): 0, (33.1% identity in 544 aa overlap); contains PS00523 Sulfatases signature 1. Also similar to MTCY21 (atsD) {Mycobacterium tuberculosis H37Rv (lab strain)}
662Rv0664hypothetical protein Rv0664 {Mycobacterium tuberculosis H37Rv (lab strain)}
663Rv0665hypothetical protein Rv0665 {Mycobacterium tuberculosis H37Rv (lab strain)}
664Rv0666hypothetical protein Rv0666 {Mycobacterium tuberculosis H37Rv (lab strain)}
665Rv0667, (MTCI376.08c) ,len: 1172, rpoB, dna-directed rna polymerase beta chain, start site chosen on basis ofrbs but alternative start at position 14359), FASTA score:almost identical to MSGRPOB_1 Mycobacterium tuberculosis RPOB_MYCTU P47766 (rpoB) {Mycobacterium tuberculosis H37Rv (lab strain)}
666Rv0668, (MTCI376.07c), len: 1316 aa, rpoC, dna-directed rna polymerase beta chain), FASTA score: RPOC_BACSU P37871 (EC 2.7.7.6) (1199 aa) opt: 2367 z-score: 2561.4 E():0, (52.9% identity in 1317 aa overlap), highly similar to M. leprae RPOC_MYCLE P30761 dna-dir (rpoC) {Mycobacterium tuberculosis H37Rv (lab strain)}
667Rv0669chypothetical protein Rv0669c {Mycobacterium tuberculosis H37Rv (lab strain)}
668Rv0670, (MTCI376.04c), len: 252, end, Probable endonuclease IV (apurinase). Contains PS00729 AP endonucleasesfamily 2 signatures 1 and 2 (PS00729, PS00730). FASTA score: MLB1790G_5 END_MYCLE P30770 probable endonuclease (ec 3.1.21.-) (252 aa) opt: 1463, E(): 0; (end) {Mycobacterium tuberculosis H37Rv (lab strain)}
669Rv0671, (MTCI376.03c), len: 280, lpqP, Similar to hypothetical M. leprae protein and to various esterases and poly(3-hydroxyalkanoate) depolymerases. Probably lipoprotein with 17 aa signal sequence as it contains appropriately positioned (PS00013) Prokaryotic m (lpqP) {Mycobacterium tuberculosis H37Rv (lab strain)}
670Rv0672, (MTCI376.02c), len: 545, fadE8, probable acylCo-A dehydrogenase like E. coli AidB protein. Contains PS00073 Acyl-CoA dehydrogenases signature 2. FASTA score: AIDB_ECOLI P33224 aidb protein (546 aa) opt: 1369 E(): 0; (44.1%identity in 524 aa overlap). Al (fadE8) {Mycobacterium tuberculosis H37Rv (lab strain)}
671Rv0673, (MTCI376.01c-MTV040.01), len: 312. echA4, some similarity to enoyl CoA hydratases. Contains PS00017 ATP/GTP-binding site motif A (P-loop). FASTA score: Q52995 ENOYL COA HYDRATASE opt: 210; E(): 1.2e-06; (27.9% identity in 280 aa overlap). Also similar t (echA4) {Mycobacterium tuberculosis H37Rv (lab strain)}
672Rv0674hypothetical protein Rv0674 {Mycobacterium tuberculosis H37Rv (lab strain)}
673Rv0675, (MTV040.03), len: 263. echA5, Probable enoyl CoA-hydratase similar to several e.g. C. elegans Q20376 (258 aa)and Mycobacterium tuberculosis MTCY8D5_17 (262 aa).FASTAscores: sptr|Q20376|Q20376 SIMILAR TO ENOYL-COA HYDRATASE.(258 aa) opt: 697 z-score: 825 (echA5) {Mycobacterium tuberculosis H37Rv (lab strain)}
674Rv0676c, (MTV040.04c), len: 964. Probable membrane protein similar to many in mycobacteria e.g. P54881|YV34_MYCLE (959 aa). FASTA scores: sp|P54881|YV34_MYCLE HYPOTHETICAL 105.2 KD PROTEIN U17 (959 aa) opt: 3991 z-score: 4375.4 E(): 0; 62.8% identity in 933 aa o (mmpL5) {Mycobacterium tuberculosis H37Rv (lab strain)}
675Rv0677c, (MTV040.05c), len: 142. Possible membrane protein similar to many in mycobacteria similar to e.g. Mycobacterium leprae U1740w, P54880|YV33_MYCLE (154 aa). Several alternative starts possible but no RBS apparent. FASTA scores: sp|P54880|YV33_MYCLE HYPOTH (mmpS5) {Mycobacterium tuberculosis H37Rv (lab strain)}
676Rv0678hypothetical protein Rv0678 {Mycobacterium tuberculosis H37Rv (lab strain)}
677Rv0679chypothetical protein Rv0679c {Mycobacterium tuberculosis H37Rv (lab strain)}
678Rv0680chypothetical protein Rv0680c {Mycobacterium tuberculosis H37Rv (lab strain)}
679Rv0681hypothetical protein Rv0681 {Mycobacterium tuberculosis H37Rv (lab strain)}
680Rv0682, (MTV040.10), len: 124, rpsL, identical to 30S ribosomal protein S12. Contains PS00055 Ribosomal protein S12 signature. FASTA scores: gp|X70995|MTDRPS12_1 M.tuberculosis gene for ribosomal (124 aa) opt: 799 z-score: 1004.8 E(): 0; 100.0% identity in 124 (rpsL) {Mycobacterium tuberculosis H37Rv (lab strain)}
681Rv0683, (MTV040.11), len: 156. rpsG, 30S ribosomalprotein S7. Contains PS00052 Ribosomal protein S7 signature. FASTA scores: gp|L34681|MSGRPSLG_2 Mycobacterium smegmatis ribosomal (156 aa) opt: 986 z-score: 1214.6 E(): 0; 96.2% identity in 156 aa overlap. TBpar (rpsG) {Mycobacterium tuberculosis H37Rv (lab strain)}
682Rv0684, (MTV040.12-MTCY210.01), len: 701. fusA, elongation factor G. Contains PS00017 ATP/GTP-binding site motif A (P-loop) and PS00301 GTP-binding elongation factors signature. FASTA scores: sp|P30767|EFG_MYCLE ELONGATION FACTOR G (EF-G) (701 aa) opt: 2521 z-s (fusA) {Mycobacterium tuberculosis H37Rv (lab strain)}
683Rv0685, (MTCY210.02), len: 396, tuf, identical to EFTU_MYCTU P31501 elongation factor tu (ef-tu) (396 aa), score is 0.854; contains PS00017 ATP/GTP-binding site motif A,PS00301 GTP-binding elongation factors signature (tuf) {Mycobacterium tuberculosis H37Rv (lab strain)}
684Rv0686hypothetical protein Rv0686 {Mycobacterium tuberculosis H37Rv (lab strain)}
685Rv0687hypothetical protein Rv0687 {Mycobacterium tuberculosis H37Rv (lab strain)}
686Rv0688hypothetical protein Rv0688 {Mycobacterium tuberculosis H37Rv (lab strain)}
687Rv0689chypothetical protein Rv0689c {Mycobacterium tuberculosis H37Rv (lab strain)}
688Rv0690chypothetical protein Rv0690c {Mycobacterium tuberculosis H37Rv (lab strain)}
689Rv0691chypothetical protein Rv0691c {Mycobacterium tuberculosis H37Rv (lab strain)}
690Rv0692hypothetical protein Rv0692 {Mycobacterium tuberculosis H37Rv (lab strain)}
691Rv0693, (MTCY210.10), len: 391 aa, similar to eg AE001109_9 Archaeoglobus fulgidus O30258 COENZYME PQQ SYNTHESIS PROTEIN (PQQE) (375 aa), E(): 1.6e-16, 28.1% identity in377 aa overlap; and PQQE_ACICA P07782 coenzyme pqq synthesis protein e (384 aa),fasta scores (pqqE) {Mycobacterium tuberculosis H37Rv (lab strain)}
692Rv0694, (MTCY210.11), len: 396 aa, similar to eg LLDD_ECOLI P33232 l-lactate dehydrogenase (cytochrome) (396 aa), fasta scores, opt: 697, E(): 0, (34.5% identity in 380 aa overlap), score is 0.918 (lldD1) {Mycobacterium tuberculosis H37Rv (lab strain)}
693Rv0695hypothetical protein Rv0695 {Mycobacterium tuberculosis H37Rv (lab strain)}
694Rv0696hypothetical protein Rv0696 {Mycobacterium tuberculosis H37Rv (lab strain)}
695Rv0697hypothetical protein Rv0697 {Mycobacterium tuberculosis H37Rv (lab strain)}
696Rv0698hypothetical protein Rv0698 {Mycobacterium tuberculosis H37Rv (lab strain)}
697Rv0699hypothetical protein Rv0699 {Mycobacterium tuberculosis H37Rv (lab strain)}
698Rv0700, (MTCY210.19), len: 101 . rpsJ, 30S RIBOSOMAL PROTEIN S10, similar to many, e.g. to RS10_MYCLE P30765 30s ribosomal protein s10, (101 aa), fasta scores, opt: 645, E(): 0, (97.0% identity in 101 aa overlap), contains PS00361 Ribosomal protein S10 signatur (rpsJ) {Mycobacterium tuberculosis H37Rv (lab strain)}
699Rv0701, (MTCY210.20), len: 217 aa, rplC , similar to RL3_THETH P52860 ribosomal protein l3, thermus aquaticus (206 aa), fasta scores, opt: 717, E(): 0, (55.2% identity in 210 aa overlap); contains PS00474 Ribosomal protein L3 signature (rplC) {Mycobacterium tuberculosis H37Rv (lab strain)}
700Rv0702, (MTCY210.21), len: 223, rplD , similar to eg RL4_BACST P28601 50s ribosomal protein l4 (207 aa), fastascores, opt: 522, E(): 3.5e-26, (42.4% identity in 198 aa overlap). Also similar to MLCB2492_3 Mycobacterium leprae rplDand MSRPLD_1 Mycobacterium smeg (rplD) {Mycobacterium tuberculosis H37Rv (lab strain)}
701Rv0703, (MTCY21.22), len: 100, rplW, similar to egRL23_BACST P04454 50s ribosomal protein l23 (95 aa), fastascores, opt: 275, E(): 1.4e-13, (50.5% identity in 95 aa overlap); also similar to MLCB2492_4 Mycobacterium leprae RIBOSOMAL PROTEIN L23, contains PS0005 (rplW) {Mycobacterium tuberculosis H37Rv (lab strain)}
702Rv0704, (MTCY210.23), len: 280, rplB, almost identical to MBS10OPER_5 Mycobacterium bovis BCG and MLCB2492_5Mycobacterium leprae rplB, also similar to eg RL2_BACSU P42919 50s ribosomal protein l2 (bl2) (276 aa), fasta scores,opt: 1179, E(): 0, (61.1% identity i (rplB) {Mycobacterium tuberculosis H37Rv (lab strain)}
703Rv0705, (MTCY210.24), len: 93, rpsS, near identical to M. bovis RS19_MYCBO P48947 30s ribosomal protein s19 (93 aa), fasta scores, opt: 623, E(): 0, (98.9% identity in 93 aa overlap); contains PS00323 Ribosomal protein S19 signature (rpsS) {Mycobacterium tuberculosis H37Rv (lab strain)}
704Rv0706, (MTCY210.25), len: 197 aa, rplV, almost identical to MBS10OPER_7 Mycobacterium bovis BCG and MLCB2492_7 Mycobacterium leprae RIBOSOMAL PROTEIN L22. Also similarto eg RL22_BACSU P42060 50s ribosomal protein l22 (113 aa),fasta scores, opt: 368, E(): 2.4e- (rplV) {Mycobacterium tuberculosis H37Rv (lab strain)}
705Rv0707, (MTCY210.26), len: 274 aa, rpsC, almost identical to MBS10OPER_8 Mycobacterium bovis BCG and MLCB2492_8 Mycobacterium leprae RIBOSOMAL PROTEIN S3; similar also to eg RS3_BACSU P21465 30s ribosomal protein s3 (bs3) (bs2) (217 aa), fasta scores, opt: 794, (rpsC) {Mycobacterium tuberculosis H37Rv (lab strain)}
706Rv0708, (MTCY210.27), rplP, len: 138, Almost identical to MBS10OPER_9 Mycobacterium bovis BCG, and MLCB2492_9 Mycobacterium leprae RIBOSOMAL PROTEIN L16;also similar to eg RL16_BACSU P14577, 50s ribosomal protein l16 (144 aa), fasta scores, opt: 600, E(): 0, (6 (rplP) {Mycobacterium tuberculosis H37Rv (lab strain)}
707Rv0709, (MTCY210.28, rpmC gene), len: 77 aa, almostidentical to MBS10OPER_10 Mycobacterium bovis BCG and MLCB2492_10 Mycobacterium leprae RIBOSOMAL PROTEIN L29; also similar to eg RL29_BACSU P12873 50s ribosomal protein l29 (66aa), fasta scores, opt: 225, E(): (rpmC) {Mycobacterium tuberculosis H37Rv (lab strain)}
708Rv0710, (MTCY210.29, rpsQ gene), len: 136 aa, almost identical to MBS10OPER_11 Mycobacterium bovis BCG and MLCB2492_11 Mycobacterium leprae RIBOSOMAL PROTEIN S17 ;also similar to eg RS17_BACSU P12874 30s ribosomal protein s17 (bs16) (86 aa), fasta scores, opt: (rpsQ) {Mycobacterium tuberculosis H37Rv (lab strain)}
709Rv0711, (MTCY210.30), len: 787, atsA, arylsulfatase, similar to eg ARS_PSEAE P51691 arylsulfatase (ec 3.1.6.1) (532 aa), fasta scores, opt: 439, E(): 2.9e-21, (30.8% identity in 552 aa overlap); also similar to MTCI418A_1, (38.4% identity in 797 aa overlap); an (atsA) {Mycobacterium tuberculosis H37Rv (lab strain)}
710Rv0712hypothetical protein Rv0712 {Mycobacterium tuberculosis H37Rv (lab strain)}
711Rv0713hypothetical protein Rv0713 {Mycobacterium tuberculosis H37Rv (lab strain)}
712Rv0714, (MTCY210.33), len: 122 aa, rplN, highly similar to MLCB2492_14 Mycobacterium leprae O32993 RIBOSOMAL PROTEIN L14, also RL14_MICLU P33100 50s ribosomal protein l14 (122 aa), fasta scores, opt: 674, E(): 0, (85.2% identity in 122 aa overlap);contains PS00 (rplN) {Mycobacterium tuberculosis H37Rv (lab strain)}
713Rv0715, (MTCY210.34, rplX gene), len: 105 aa, similar to MLCB2492_15 Mycobacterium leprae O32994 RIBOSOMAL PROTEIN L24, also to eg RL24_BACSU P12876 50s ribosomal protein l24 (bl23) (103 aa), fasta scores, opt: 363, E(): 1.8e-18, (56.7% identity in 104 aa overl (rplX) {Mycobacterium tuberculosis H37Rv (lab strain)}
714Rv0716, (MTCY210.35), len: 187 aa, rplE, similar toMLCB2492_16 Mycobacterium leprae RL5_MICLU 50S RIBOSOMAL PROTEIN L5; also similar to eg RL5_MICLU P33098 50s ribosomalprotein l5, (191 aa), fasta scores, opt: 930, E(): 0, (73.8% identity in 183 aa overlap) (rplE) {Mycobacterium tuberculosis H37Rv (lab strain)}
715Rv0717, (MTCY210.36), len: 61 aa, rpsN, almost identical to MLCB2492_17 Mycobacterium leprae O32996 RIBOSOMAL PROTEIN S14 , also similar to RS14_THETH P24320 30s ribosomal protein s14 (60 aa), fasta scores, opt: 316, E(): 2e-19,(70.0% identity in 60 aa overlap) (rpsN) {Mycobacterium tuberculosis H37Rv (lab strain)}
716Rv0718, (MTCY210.37), len: 132 aa, rpsH, highly similar to MLCB2492_18 Mycobacterium leprae O32997 RIBOSOMAL PROTEIN S8; also similar to RS8_MICLU P33106 30s ribosomal protein s8 (132 aa), fasta scores, opt: 669, E(): 0, (77.3% identity in 132 aa overlap); cont (rpsH) {Mycobacterium tuberculosis H37Rv (lab strain)}
717Rv0719, (MTCY210.38), len: 179 aa, rplF, almost identical to MLCB2492_19 Mycobacterium leprae O32998 RIBOSOMALPROTEIN L6; also highly similar to RL6_STRCO P46786 50s ribosomal protein l6. streptomyces (179 aa), fasta scores, opt: 872, E(): 0, (70.4% identity in (rplF) {Mycobacterium tuberculosis H37Rv (lab strain)}
718Rv0720, (MTCY210.39), len: 122 aa, rplR, almost identical to MLCB2492_20 Mycobacterium leprae O32999 RIBOSOMALPROTEIN L18; also highly similar to eg RL18_MICLU P33102 50s ribosomal protein l18 (119 aa), fasta scores, opt: 447, E(): 8.7e-24, (60.4% identity in 1 (rplR) {Mycobacterium tuberculosis H37Rv (lab strain)}
719Rv0721, (MTCY210.40), len: 220 aa, rpsE, almost identical to M. lepraeMLCB2492_21 RIBOSOMAL PROTEIN S5; also highly similar to RS5_STRCO P46790 30s ribosomal protein s5.streptomyces (167 aa), fasta scores, opt: 889, E(): 0, (82.1% identity in 162 aa overlap); e (rpsE) {Mycobacterium tuberculosis H37Rv (lab strain)}
720Rv0722, (MTCY210.41), len: 65 aa, rpmD, almost identical to M. leprae O33001 RIBOSOMAL PROTEIN L30; also similar to eg SW:P02430 RL30_ECOLI 50S ribosomal protein L30. [0] (58 aa), fasta scores, opt: 168, E(): 1.5e-13, (53.7% identity in 54 aa overlap) (rpmD) {Mycobacterium tuberculosis H37Rv (lab strain)}
721Rv0723, (MTCY210.42), len: 146 aa, rplO, almost identical to MLCB2492_23 Mycobacterium leprae O33002 RIBOSOMALPROTEIN L15. Also similar to eg RL15_BACSU P19946 50s ribosomal protein l15 (146 aa), fasta scores, opt: 419, E(): 6.5e-20, (51.0% identity in 145 aa o (rplO) {Mycobacterium tuberculosis H37Rv (lab strain)}
722Rv0724, (MTCY210.43), len: 623, sppA, ENDOPEPTIDASEIV, similar to MLCB2492_24 Mycobacterium leprae O33003 ENDOPEPTIDASE IV; also similar to SPPA_ECOLI P08395 protease iv(endopeptidase) (618 aa), fasta scores, opt: 582, E(): 8.9e-27, (34.1% identity in 525 aa ov (sppA) {Mycobacterium tuberculosis H37Rv (lab strain)}
723Rv0725chypothetical protein Rv0725c {Mycobacterium tuberculosis H37Rv (lab strain)}
724Rv0726chypothetical protein Rv0726c {Mycobacterium tuberculosis H37Rv (lab strain)}
725Rv0727c, (MTV41.01c-MTCY210.46c), len: 218. fucA, probable fuculose- 1-phosphate aldolase similar to many. eg sp|P11550|FUCA_ECOLI L-FUCULOSE PHOSPHATE ALDOLASE (EC (215aa), FASTA scores: opt: 372 z-score: 478.1 E(): 4.1e-19;34.6% identity in 185 aa overlap. TBp (fucA) {Mycobacterium tuberculosis H37Rv (lab strain)}
726Rv0728chypothetical protein Rv0728c {Mycobacterium tuberculosis H37Rv (lab strain)}
727Rv0729, (MTV041.03), len: 448. Unknown, but similarto xylA/xylB genes from various bacterial species, e.g. gp|K01996|ECOXYLABA_2 E.coli xylA gene coding for xylo (484 aa). FASTA scores: opt: 260 z-score: 293.6 E(): 7.5e-09. 25.9% identity in 478 aa overlap. Als (xylB) {Mycobacterium tuberculosis H37Rv (lab strain)}
728Rv0730hypothetical protein Rv0730 {Mycobacterium tuberculosis H37Rv (lab strain)}
729Rv0731chypothetical protein Rv0731c {Mycobacterium tuberculosis H37Rv (lab strain)}
730Rv0732, (MTV041.06), len: 441. SecY subunit of preprotein translocase. Highly similar to transmembrane proteins of various species. FASTA scores: gp|U77912|MBU77912_1 Mycobacterium bovis preprotein tr (441 aa). opt: 2802 z-score: 3442.5 E(): 0. 99.8% identity i (secY) {Mycobacterium tuberculosis H37Rv (lab strain)}
731Rv0733, (MTV041.07), adk, len: 181. Probable adenylate kinase (adk), ATP-AMP transphosphorylase similar to many, e.g. Mycobacterium leprae. FASTA scores: gp|Z98756|MLCB2492_28 M. leprae cosmid B249 (181 aa) opt: 978 z-score: 1132.8 E(): 0. 83.6% identity in 177 (adk) {Mycobacterium tuberculosis H37Rv (lab strain)}
732Rv0734, (MTV041.08, map), len: 266. Probable methionine amino peptidase (map), Highly similar to many e.g. M. leprae FASTA scores: gp|Z98756|MLCB2492_29 M. leprae cosmidB249 (266 aa) z-score: 1717.3 E(): 0. 83.4% identity in 265aa overlap; Start uncertain, alte (map) {Mycobacterium tuberculosis H37Rv (lab strain)}
733Rv0735, (MTV041.09, sigL), len: 177. Probable RNA polymerase sigma factor, similar to many proteins of the extracytoplasmatic function (ECF) subfamily e.g. Myxococcus xanthus, FASTA scores: sp|Q06909|CARQ_MYXXA RNA POLYMERASE SIGMA FACTOR CARQ. (174 aa).opt: 25 (sigL) {Mycobacterium tuberculosis H37Rv (lab strain)}
734Rv0736hypothetical protein Rv0736 {Mycobacterium tuberculosis H37Rv (lab strain)}
735Rv0737hypothetical protein Rv0737 {Mycobacterium tuberculosis H37Rv (lab strain)}
736Rv0738hypothetical protein Rv0738 {Mycobacterium tuberculosis H37Rv (lab strain)}
737Rv0739hypothetical protein Rv0739 {Mycobacterium tuberculosis H37Rv (lab strain)}
738Rv0740hypothetical protein Rv0740 {Mycobacterium tuberculosis H37Rv (lab strain)}
739Rv0741hypothetical protein Rv0741 {Mycobacterium tuberculosis H37Rv (lab strain)}
740Rv0742, (MTV041.16), len: 175. Unknown, member of PE-family, PGRS subfamily of glycine-rich protein, similar to many M. tuberculosis PGRS-type proteins. e.g. gp|Z78020|MTCY1A11_25 M. tuberculosis cosmi (498 aa). Similarity suggests ORF starts with ATA start cod (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
741Rv0743chypothetical protein Rv0743c {Mycobacterium tuberculosis H37Rv (lab strain)}
742Rv0744chypothetical protein Rv0744c {Mycobacterium tuberculosis H37Rv (lab strain)}
743Rv0745hypothetical protein Rv0745 {Mycobacterium tuberculosis H37Rv (lab strain)}
744Rv0746, (MTV041.20), len: 783. Member of PE_PGRS family of Glycine-rich proteins, highly similar to antigen wag22; MTCY28.25c, FASTA scores: gp|Z95890|MTCY28_25 M. tuberculosis cosmid (914 aa) opt: 2429 z-score: 1475.6 E(): 0.56.9% identity in 873 aa overlap. A (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
745Rv0747, (MTV041.21), len: 801. Member of PGRS family of Glycine-rich proteins, highly similar to MTCY28.25c -antigen wag22. FASTA scores: gp|Z95890|MTCY28_25 M. tuberculosis cosmid (914 aa) opt: 2772 z-score: 1643.0 E(): 0. 60.9% identity in 941 aa overlap. Als (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
746Rv0748hypothetical protein Rv0748 {Mycobacterium tuberculosis H37Rv (lab strain)}
747Rv0749hypothetical protein Rv0749 {Mycobacterium tuberculosis H37Rv (lab strain)}
748Rv0750hypothetical protein Rv0750 {Mycobacterium tuberculosis H37Rv (lab strain)}
749Rv0751c, (MTV041.25c), len: 294. mmsB. probable 3-hydroxyisobutyrate dehydrogenase - methylmalonate semialdehyde dehydrogenase, highly similar to many e.g. gp|M84911|PSEMMSRAB_3 Pseudomonas aeruginosa methylmal (298 aa). FASTA scores:opt: 786 z-score: 913.0 E(): (mmsB) {Mycobacterium tuberculosis H37Rv (lab strain)}
750Rv0752c, (MTV041.26c), len: 390, acd , fadE9, probable acyl-CoA dehydrogenase, ,similar to many other acyl-CoA dehydrogenases e.g. gp|Z99123|BSUB0020_14 B. subtilis complete genome (379 aa) FASTA scores: opt: 853 z-score: 958.3 E(): 0. 39.8% identity in 384 aa o (fadE9) {Mycobacterium tuberculosis H37Rv (lab strain)}
751Rv0753c, (MTV041.27c), len: 510. mmsA, probable methylmalonate semialdehyde dehydrogenase, (mmsA), similar to many e.g. gp|M84911|PSEMMSRAB_2 Pseudomonas aeruginosa methylmal (497 aa).opt: 1127 z-score: 1345.6 E(): 0; 47.9% identity in 507 aa overlap, or gp|L485 (mmsA) {Mycobacterium tuberculosis H37Rv (lab strain)}
752Rv0754, (MTV041.28), len: 584. Unknown glycine richprotein, similar to other PE_PGRS type hypothetical proteins e.g. gp|AL0212|MTV008_46 M. tuberculosis sequenc (1660 aa); 48.7% identity in 345 aa overlap or gp|Z80225|MTCY441_4M. tuberculosis cosmid (778 aa); 4 (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
753Rv0755c, (MTV041.29), len: 645. Member of PPE family, (Gly-, Ala-, Asn-rich PPE family). Similar to gp|Z82098|MTCY3C7_23 M. tuberculosis cosmid (582 aa), 56.1% identityin 636 aa overlap; or gp|Z92774|MTCY6G11_5 M. tuberculosiscosmid (552 aa), 55.8% identity in 5 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
754Rv0756chypothetical protein Rv0756c {Mycobacterium tuberculosis H37Rv (lab strain)}
755Rv0757, (MTCY369.02), len: 247, phoP-like, similar to PHOP_BACSU P13792 alkaline phosphatase synthesis transcription regulatory protein (240 aa), fasta scores, opt: 594, E(): 2.3e-33, (41.0% identity in 234 aa overlap), also similar to MTCY31.31c (45.4% identit (phoP) {Mycobacterium tuberculosis H37Rv (lab strain)}
756Rv0758, (MTCY369.03), len: 485, phoR-like similar to PHOR_BACSU P23545 alkaline phosphatase synthesis sensor (579 aa), fasta scores, opt: 515, E(): 1.9e-25, (40.0% identity in 230 aa overlap), also similar to MTCY20G9.16, 34.5% identity in 264 aa overlap), MTU8 (phoR) {Mycobacterium tuberculosis H37Rv (lab strain)}
757Rv0759chypothetical protein Rv0759c {Mycobacterium tuberculosis H37Rv (lab strain)}
758Rv0760chypothetical protein Rv0760c {Mycobacterium tuberculosis H37Rv (lab strain)}
759Rv0761c, (MTCY369.06c), len: 375, adhB, alcohol dehydrogenase, similar to eg ADH1_RABIT Q03505 alcohol dehydrogenase alpha chain (ec (374 aa), fasta scores, opt: 872, E(): 0, (39.1% identity in 379 aa overlap); contains PS00059 Zinc-containing alcohol dehydrogen (adhB) {Mycobacterium tuberculosis H37Rv (lab strain)}
760Rv0762chypothetical protein Rv0762c {Mycobacterium tuberculosis H37Rv (lab strain)}
761Rv0763chypothetical protein Rv0763c {Mycobacterium tuberculosis H37Rv (lab strain)}
762Rv0764chypothetical protein Rv0764c {Mycobacterium tuberculosis H37Rv (lab strain)}
763Rv0765chypothetical protein Rv0765c {Mycobacterium tuberculosis H37Rv (lab strain)}
764Rv0766chypothetical protein Rv0766c {Mycobacterium tuberculosis H37Rv (lab strain)}
765Rv0767chypothetical protein Rv0767c {Mycobacterium tuberculosis H37Rv (lab strain)}
766Rv0768, (MTCY369.13), len: 489, aldA, probable aldehyde dehydrogenase, similar to eg DHAB_ATRHO P42757 betaine-aldehyde dehydrogenase precursor (502 aa), fasta scores, opt: 1001, E(): 0, (35.6% identity in 486 aa overlap); contains PS00687 Aldehyde dehydrogenas (aldA) {Mycobacterium tuberculosis H37Rv (lab strain)}
767Rv0769hypothetical protein Rv0769 {Mycobacterium tuberculosis H37Rv (lab strain)}
768Rv0770hypothetical protein Rv0770 {Mycobacterium tuberculosis H37Rv (lab strain)}
769Rv0771hypothetical protein Rv0771 {Mycobacterium tuberculosis H37Rv (lab strain)}
770Rv0772, (MTCY369.17), len: 422, purD, highly similar to M. leprae,PUR2_MYCLE PHOSPHORIBOSYLAMINE--GLYCINE Q50144 PURD purD (422 aa), fasta scores, opt: 2272, E(): 0, (81.8% identity in 422 aa overlap), similar to PUR2_ECOLI P15640 phosphoribosylamine--glycine l (purD) {Mycobacterium tuberculosis H37Rv (lab strain)}
771Rv0773c, (MTCY369.18), len: 512,ggtA, putative gamma-glutamyl transpeptidase, similar to Z93767|BSZ93767_6 NID: O05218 - Bacillus (525 aa) opt: 1169; E(): 0; 40.1% identityin 516 aa overlap. Also similar to PAC1_PSES3 P15557 cephalosporin acylase i (557 aa), fas (ggtA) {Mycobacterium tuberculosis H37Rv (lab strain)}
772Rv0774chypothetical protein Rv0774c {Mycobacterium tuberculosis H37Rv (lab strain)}
773Rv0775hypothetical protein Rv0775 {Mycobacterium tuberculosis H37Rv (lab strain)}
774Rv0776chypothetical protein Rv0776c {Mycobacterium tuberculosis H37Rv (lab strain)}
775Rv0777, (MTCY369.21b), len: 472, purB, adenylosuccinate lyase, highly similar to MLCB5.13. FASTA score: Z95151| g2076607 - Mycobacterium leprae (487 aa) opt: 2640 E(): 0; 86.7% identity in 472 aa overlap. More similar to eukaryotic adenylosuccinate lyases than (purB) {Mycobacterium tuberculosis H37Rv (lab strain)}
776Rv0778hypothetical protein Rv0778 {Mycobacterium tuberculosis H37Rv (lab strain)}
777Rv0779chypothetical protein Rv0779c {Mycobacterium tuberculosis H37Rv (lab strain)}
778Rv0780, (MTCY369.24), len: 297, almost identical topurC, MTU34957_1 phosphoribosylaminoimidazole-succinocarboxamide synthase (purC) (297 aa), fasta scores, opt: 1986, E(): 0, (99.3% identity in 297 aa overlap); contains PS01058SAICAR synthetase signature 2 (purC) {Mycobacterium tuberculosis H37Rv (lab strain)}
779Rv0781, (MTCY369.25), len: 236, ptrBb, similar to the N-terminal region of PTRB_ECOLI P24555 protease ii (707 aa), fasta scores, opt: 204, E(): 7.4e-07, (29.6% identity in 230 aa overlap), MTCY369.25 and 26 appear to be a frameshifted homologue of protease II, (ptrBb) {Mycobacterium tuberculosis H37Rv (lab strain)}
780Rv0782, (MTCY369.26), len: 552, ptrBa, similar to the C-terminal region of PTRB_ECOLI P24555 protease ii (707aa), fasta scores, opt: 1251, E(): 0, (42.7% identity in 489 aa overlap), MTCY369.25 and 26 appear to be a frameshifted homologue of protease II, we can (ptrBa) {Mycobacterium tuberculosis H37Rv (lab strain)}
781Rv0783chypothetical protein Rv0783c {Mycobacterium tuberculosis H37Rv (lab strain)}
782Rv0784hypothetical protein Rv0784 {Mycobacterium tuberculosis H37Rv (lab strain)}
783Rv0785hypothetical protein Rv0785 {Mycobacterium tuberculosis H37Rv (lab strain)}
784Rv0786chypothetical protein Rv0786c {Mycobacterium tuberculosis H37Rv (lab strain)}
785Rv0787hypothetical protein Rv0787 {Mycobacterium tuberculosis H37Rv (lab strain)}
786Rv0788, (MTCY369.32), len: 224, purQ, phosphoribosylformylglycinamidine synthase I equivalent to M. leprae MLCB5_24 Z95151 O05756 PURQ - (224 aa) FASTA score: opt: 1341; E(): 0; 88.7% identity in 222 aa overlap. Also similar to PURQ_BACSU P12041 (227 aa), fasta (purQ) {Mycobacterium tuberculosis H37Rv (lab strain)}
787Rv0789chypothetical protein Rv0789c {Mycobacterium tuberculosis H37Rv (lab strain)}
788Rv0790chypothetical protein Rv0790c {Mycobacterium tuberculosis H37Rv (lab strain)}
789Rv0791chypothetical protein Rv0791c {Mycobacterium tuberculosis H37Rv (lab strain)}
790Rv0792chypothetical protein Rv0792c {Mycobacterium tuberculosis H37Rv (lab strain)}
791Rv0793hypothetical protein Rv0793 {Mycobacterium tuberculosis H37Rv (lab strain)}
792Rv0794c, (MTV042.04c), len: 499. Identical to Mycobacterium tuberculosis protein described as mercuric reductase/glutathione reductase/dihydrolipoamide dehydrogenase MTY13470_1 (499 aa). Length is more consistent with dihydrolipoamide dehydrogenase than mercuric (lpdB) {Mycobacterium tuberculosis H37Rv (lab strain)}
793Rv0795hypothetical protein Rv0795 {Mycobacterium tuberculosis H37Rv (lab strain)}
794Rv0796hypothetical protein Rv0796 {Mycobacterium tuberculosis H37Rv (lab strain)}
795Rv0797hypothetical protein Rv0797 {Mycobacterium tuberculosis H37Rv (lab strain)}
796Rv0798chypothetical protein Rv0798c {Mycobacterium tuberculosis H37Rv (lab strain)}
797Rv0799chypothetical protein Rv0799c {Mycobacterium tuberculosis H37Rv (lab strain)}
798Rv0800, (MTCY07H7A.09c), len: 433 aa, highly similar to Mycobacterium leprae Q50022 PEPX (443 aa), fasta scores, opt: 2237, E(): 0, (78.3% identity in 433 aa overlap), similar to AMPL_YEAST P14904 vacuolar aminopeptidase i precursor ( (514 aa), fasta scores, op (pepC) {Mycobacterium tuberculosis H37Rv (lab strain)}
799Rv0801hypothetical protein Rv0801 {Mycobacterium tuberculosis H37Rv (lab strain)}
800Rv0802chypothetical protein Rv0802c {Mycobacterium tuberculosis H37Rv (lab strain)}
801Rv0803, (MTCY07H7A.06c), len: 754 aa, purL, phosphoribosylformylglycinamidine synthase involved in the FOURTHSTEP IN DE NOVO PURINE BIOSYNTHESIS, almost identical to gp|U34956|MTU34956_1 Mycobacterium tuberculosis Q50023 PURL (754 aa); 99.2% identity in 754 aa (purL) {Mycobacterium tuberculosis H37Rv (lab strain)}
802Rv0804hypothetical protein Rv0804 {Mycobacterium tuberculosis H37Rv (lab strain)}
803Rv0805hypothetical protein Rv0805 {Mycobacterium tuberculosis H37Rv (lab strain)}
804Rv0806c, (MTCY07H7A.03), len: 532 aa, cpsY, highly similar to M. leprae Q50025 CPSY (542 aa), fasta scores, opt: 2964, E(): 0, (82.3% identity in 530 aa overlap), some similarity to NEISSERIA MENINGITIDIS Q51151 capsule gene complex UPD-glucose-4-epimerase (373 (cpsY) {Mycobacterium tuberculosis H37Rv (lab strain)}
805Rv0807hypothetical protein Rv0807 {Mycobacterium tuberculosis H37Rv (lab strain)}
806Rv0808, (MTCY07H7A.01c), len: 527 aa, purF, highly similar to MLCB5_32, Mycobacterium leprae Q50028 PURF, (91.3% identity in 518 aa overlap) . Also similar to eg PUR1_BACSU P00497 amidophosphoribosyltransferase precuror (476 aa), fasta scores, opt: 1412, E(): 0 (purF) {Mycobacterium tuberculosis H37Rv (lab strain)}
807Rv0809, (MTV043.01), len: 364. purM, probable 5-phosphoribosyl-5-aminoimidazole synthetase, similar to many e.g. P12043|PUR5_BACSU (346 aa) and Salmonella typhimurium U68765|STU68765_2 (345 aa). FASTA scores: sp|P12043|PUR5_BACSU PHOSPHORIBOSYLFORMYLGLYCINAMIDI (purM) {Mycobacterium tuberculosis H37Rv (lab strain)}
808Rv0810chypothetical protein Rv0810c {Mycobacterium tuberculosis H37Rv (lab strain)}
809Rv0811chypothetical protein Rv0811c {Mycobacterium tuberculosis H37Rv (lab strain)}
810Rv0812, (MTV043.04), len: 289. pabC, similar to sp|P28305|PABC_ECOLI 4-AMINO-4-DEOXYCHORISMATE LYASE ( (269 aa). FASTA scores: opt: 165 z-score: 205.5 E(): 0.00064, (26.8% identity in 198 aa overlap). Also similar to several ILVE proteins. TBparse score is 0.91 (pabC) {Mycobacterium tuberculosis H37Rv (lab strain)}
811Rv0813chypothetical protein Rv0813c {Mycobacterium tuberculosis H37Rv (lab strain)}
812Rv0814c, (MTV043.06c), len: 100. Unknown but identical to Mycobacterium tuberculosis MTCY164.28 (100 aa). Equivalent to hypothetical M. leprae protein G699208 U2266J (143 aa) and similar to S.erythraea rhodanese-like protein M29612|SERCYSA_5 (101 aa). FASTA scor (sseC2) {Mycobacterium tuberculosis H37Rv (lab strain)}
813Rv0815c, (MTV043.07c), len: 277, cysA2, probable thiosulfate sulfurtransferase, identical to MTCY164.27, cysA.Very similar to CysA of M. leprae and putative thiosulfatesulfurtransferases. Contains PS00683 Rhodanese C-terminalsignature at C-terminus. FASTA scores (cysA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
814Rv0816c, (MTV043.08c), len: 140. Unknown but equivalent to Mycobacterium leprae ThiX U15182|MLU15182_21 (172 aa) similar to other bacterial thioredoxins. FASTA scores: U15182|MLU15182_21 (172 aa) opt: 556 z-score: 687.4 E():8.8e-31; 63.8% identity in 141 aa over (thiX) {Mycobacterium tuberculosis H37Rv (lab strain)}
815Rv0817chypothetical protein Rv0817c {Mycobacterium tuberculosis H37Rv (lab strain)}
816Rv0818hypothetical protein Rv0818 {Mycobacterium tuberculosis H37Rv (lab strain)}
817Rv0819hypothetical protein Rv0819 {Mycobacterium tuberculosis H37Rv (lab strain)}
818Rv0820, (MTV043.12), len: 258. phoT, probable phosphate transport system ATP-binding protein, equivalent to Mycobacterium leprae protein PhoT MLU15182_28 (258 aa) and similar to many PstB proteins. Contains PS00211 ABC transporters family signature and PS00017 (phoT) {Mycobacterium tuberculosis H37Rv (lab strain)}
819Rv0821c, (MTV043.13c), len: 213. phoY-2, probable phosphate transport system regulatory protein, equivalent toMycobacterium leprae PhoY protein MLU15182_29 (222 aa), andvery similar to Mycobacterium tuberculosis MTCI418A.03c (221 aa), also known as PhoY-1. FASTA (phoY2) {Mycobacterium tuberculosis H37Rv (lab strain)}
820Rv0822chypothetical protein Rv0822c {Mycobacterium tuberculosis H37Rv (lab strain)}
821Rv0823chypothetical protein Rv0823c {Mycobacterium tuberculosis H37Rv (lab strain)}
822Rv0824c, (MTV043.16c, des), len: 338. desA1, dentical to Mycobacterium tuberculosis DES, stearyl-ACP desaturase, similar to many, and equivalent to Mycobacterium lepraeU15182|MLU15182_32 (338 aa). Contains PS00225 Crystallinsbeta and gamma Greek key motif signat (desA1) {Mycobacterium tuberculosis H37Rv (lab strain)}
823Rv0825chypothetical protein Rv0825c {Mycobacterium tuberculosis H37Rv (lab strain)}
824Rv0826hypothetical protein Rv0826 {Mycobacterium tuberculosis H37Rv (lab strain)}
825Rv0827chypothetical protein Rv0827c {Mycobacterium tuberculosis H37Rv (lab strain)}
826Rv0828chypothetical protein Rv0828c {Mycobacterium tuberculosis H37Rv (lab strain)}
827Rv0829hypothetical protein Rv0829 {Mycobacterium tuberculosis H37Rv (lab strain)}
828Rv0830hypothetical protein Rv0830 {Mycobacterium tuberculosis H37Rv (lab strain)}
829Rv0831chypothetical protein Rv0831c {Mycobacterium tuberculosis H37Rv (lab strain)}
830Rv0832, (MTV043.24), len: 137. Member of Mycobacterium tuberculosis PE family, possibly PGRS subfamily, similar to many others e.g. MTCY1A11.25c (498 aa). Appears to have incurred frameshift as next orf should be continuation, sequence has been checked but no e (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
831Rv0833, (MTV043.25), len: 749. Mycobacterium tuberculosis PE_PGRS family member but lacking N-terminal domain (present in preceding orf) , possibly due to frameshift. Very similar to MTCY28_25 (914 aa) . FASTA scores: Z95890|MTCY28_25 (914 aa) opt: 2726 z-score (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
832Rv0834c, (MTV043.26c), len: 882. Member of PE_PGRS subfamily of Mycobacterium tuberculosis Gly-, Ala-rich PE family. similar to MTCY493_4. FASTA scores: Z95844|MTCY493_4(1329 aa) opt: 2577 z-score: 1546.5 E(): 0; 52.0% identity in 950 aa overlap. TBparse score i (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
833Rv0835, (MTV043.27), len: 214. Unknown, possibly lipoprotein. Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site. FASTA scores: . TBparse score is 0.944 (lpqQ) {Mycobacterium tuberculosis H37Rv (lab strain)}
834Rv0836chypothetical protein Rv0836c {Mycobacterium tuberculosis H37Rv (lab strain)}
835Rv0837chypothetical protein Rv0837c {Mycobacterium tuberculosis H37Rv (lab strain)}
836Rv0838, (MTV043.31), len: 256. Unknown, probably lipoprotein, contains signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Some similarity to D-ALANYL-D-ALANINE DIPEPTIDASE (202 aa). FASTA scores: Transpo (lpqR) {Mycobacterium tuberculosis H37Rv (lab strain)}
837Rv0839hypothetical protein Rv0839 {Mycobacterium tuberculosis H37Rv (lab strain)}
838Rv0840chypothetical protein Rv0840c {Mycobacterium tuberculosis H37Rv (lab strain)}
839Rv0841chypothetical protein Rv0841c {Mycobacterium tuberculosis H37Rv (lab strain)}
840Rv0842hypothetical protein Rv0842 {Mycobacterium tuberculosis H37Rv (lab strain)}
841Rv0843hypothetical protein Rv0843 {Mycobacterium tuberculosis H37Rv (lab strain)}
842Rv0844c, (MTV043.37c, narL), len: 216. Probable NarL, Nitrate/nitrite response regulator protein similar to many e.g. Synechocystis sp. PCC6803 D64005|SYCSLRG_24 (209 aa). FASTA scores: D64005|SYCSLRG_24 (209 aa) opt: 438 z-score: 557.5 E(): 1.5e-23; 34.6% ident (narL) {Mycobacterium tuberculosis H37Rv (lab strain)}
843Rv0845hypothetical protein Rv0845 {Mycobacterium tuberculosis H37Rv (lab strain)}
844Rv0846chypothetical protein Rv0846c {Mycobacterium tuberculosis H37Rv (lab strain)}
845Rv0847, (MTV043.40), len: 130. Unknown, possibly lipoprotein contains possible signal sequence and PS00013 Prokaryotic membrane lipoprotein lipid attachment site. TBparse score is 0.920 (lpqS) {Mycobacterium tuberculosis H37Rv (lab strain)}
846Rv0848, (MTV043.41), len: 372. cysM3, Possible putative cystein synthase, similar to many cys genes. Start uncertain,possibly only starts at 41392. FASTA scores: sp|Q44004|CYSM_ALCEU CYSTEINE SYNTHASE (EC 4.2.99.8) ( (339 aa), opt: 511 z-score: 592.7 E(): 1.7e- (cysM3) {Mycobacterium tuberculosis H37Rv (lab strain)}
847Rv0849hypothetical protein Rv0849 {Mycobacterium tuberculosis H37Rv (lab strain)}
848Rv0850hypothetical protein Rv0850 {Mycobacterium tuberculosis H37Rv (lab strain)}
849Rv0851chypothetical protein Rv0851c {Mycobacterium tuberculosis H37Rv (lab strain)}
850Rv0852, (MTV043.45), len: 278. fadD16 similar in part to various CoA ligases. eg. gp|D49366|LEP4CCOALA_1Lithospermum erythrorhizon mRNA (636 aa), opt: 134 z-score: 162.8 E(): 0.15; 26.8% identity in 213 aa overlap, orgp|L09229|HUMFACAL_1 Human long-chain acyl-c (fadD16) {Mycobacterium tuberculosis H37Rv (lab strain)}
851Rv0853c, (MTV043.46c), len: 560. Probable pyruvate or indole-pyruvate carboxylase similar to several e.g. E. herbicola P71323 (550 aa) or E. cloacae P23234 (552 aa). Contains PS00187 Thiamine pyrophosphate enzymes signature and PS00017 ATP/GTP-binding site motif (pdc) {Mycobacterium tuberculosis H37Rv (lab strain)}
852Rv0854hypothetical protein Rv0854 {Mycobacterium tuberculosis H37Rv (lab strain)}
853Rv0855, (MTV043.48), len: 359.far, Probable fatty acid-CoA racemase similar to Mycobacterium tuberculosis MTCI65.10 (360 aa) and many eukaryotic racemases e.g. rat ALPHA-METHYLACYL-COA RACEMASE (361 aa). FASTA scores: Z95584|MTCI65_10 (360 aa) opt: 1373 z-score (far) {Mycobacterium tuberculosis H37Rv (lab strain)}
854Rv0856hypothetical protein Rv0856 {Mycobacterium tuberculosis H37Rv (lab strain)}
855Rv0857hypothetical protein Rv0857 {Mycobacterium tuberculosis H37Rv (lab strain)}
856Rv0858chypothetical protein Rv0858c {Mycobacterium tuberculosis H37Rv (lab strain)}
857Rv0859, (MTV043.52), len: 403. fadA, Probable beta-ketoadipyl CoA thiolase similar to several e.g. Pseudomonasputida 4-hydroxybenzoate beta-ketoadipyl CoA thiolase PPU10895_2 (400 aa). Contains PS00098 Thiolases acyl-enzyme intermediate signature, PS00737 Thiol (fadA) {Mycobacterium tuberculosis H37Rv (lab strain)}
858Rv0860, (MTV043.53), len: 720. fadB, probably involved in FATTY ACID BETA-OXIDATION CYCLE, similar to TRIFUNCTONAL ENZYME ALPHA SUBUNITS INVOLVED FATTY ACID METABOLISM e.g. P40939|ECHA_HUMAN (763 aa) and P21177|FADB_ECOLI (729 aa). FASTA scores: Z81043|CEC29F3_ (fadB) {Mycobacterium tuberculosis H37Rv (lab strain)}
859Rv0861chypothetical protein Rv0861c {Mycobacterium tuberculosis H37Rv (lab strain)}
860Rv0862chypothetical protein Rv0862c {Mycobacterium tuberculosis H37Rv (lab strain)}
861Rv0863hypothetical protein Rv0863 {Mycobacterium tuberculosis H37Rv (lab strain)}
862Rv0864, (MTV043.57), len: 167. moaC-2, probable MoaC-2 protein involved in molybdopterin synthesis. Unknown but similar to Mycobacterium tuberculosis MoaC, MTCY164.21 (170 aa) and other MoaC proteins e.g. A.nicotinovorans ANY10817_3 (169 aa). FASTA scores: Y108 (moaC2) {Mycobacterium tuberculosis H37Rv (lab strain)}
863Rv0865, (MTV043.58), len: 160. PROBABLE MOLYBDOPTERIN BIOSYNTHESIS MOG PROTEIN similar to several. FASTA scores: sp|P44645|MOG_HAEIN MOLYBDOPTERIN BIOSYNTHESIS MOG PRO (197 aa) opt: 306 z-score: 364.0 E(): 9e-13; 39.6% identity in 139 aa overlap; and sp|P28694| (mog) {Mycobacterium tuberculosis H37Rv (lab strain)}
864Rv0866, (MTV043.59), len: 141. moaE-2, probable Molybdopterin synthase, large subunit similar to several e.g. A.nicotinovorans ANY10817_4 (155 aa). FASTA scores: Z95150|MTCY164_30 Mycobacterium tuberculosis cosmid (147 aa)initn:255 init1: 255 opt: 321 z-score: (moaE2) {Mycobacterium tuberculosis H37Rv (lab strain)}
865Rv0867chypothetical protein Rv0867c {Mycobacterium tuberculosis H37Rv (lab strain)}
866Rv0868c, (MTV043.61c), len: 92. moaD-2, probable molybdopterin converting factor (subunit 1) weakly similar toseveral MoaD proteins e.g. Mycobacterium tuberculosis MoaD;MTCY164.22 (83 aa) and Bacillus subtilis BSUB0008_103 (77aa). FASTA scores: Z95150|MTCY164_23 (moaD2) {Mycobacterium tuberculosis H37Rv (lab strain)}
867Rv0869c, (MTV043.62c), len: 360. moaA-2, similar to A.nicotinovorans moaAANMOAA_1 (374 aa) and M. tuberculosis MTCY164.19 (359 aa). FASTA scores: X78980|ANMOAA_1 (374 aa) opt: 1059 z-score: 1258.6 E(): 0; 49.9% identity in 369 aa overlap; and Z95150|MTCY164_20 ( (moaA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
868Rv0870chypothetical protein Rv0870c {Mycobacterium tuberculosis H37Rv (lab strain)}
869Rv0871, (MTV043.64), len: 135. cspB, probable cold shock protein B, equivalent to Mycobacterium leprae MLCB57.11 (136 aa) similar to, but longer than, many L.lactis Y10181|LLCSPB_1 (66 aa). FASTA scores: Z99494|MLCB57_7 (136 aa) opt: 787 z-score: 891.7 E(): 0; (cspB) {Mycobacterium tuberculosis H37Rv (lab strain)}
870Rv0872c, (MTV043.65c), len: 606. Member of Gly-richPGRS subfamily of the Mycobacterium tuberculosis PE family,similar to many eg. MTCY24A1.04c. FASTA scores: gp|Z95207|MTCY24A1_4 Mycobacterium tuberculosis cosmid (615 aa)initn:1361 init1: 1361 opt: 2636 z-score: (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
871Rv0873, (MTV043.66-MTCY31.01), len: 650.fadE10, Probable Acyl-CoA dehydrogenase similar to many e.g. rat D30647|RATVLCAD_1 (655 aa). FASTA scores: D30647|RATVLCAD_1 Rat mRNA for very-long-chain Acyl-CoA dehydrogenase (655 aa) opt: 675 z-score: 842.3 E(): 0; 33. (fadE10) {Mycobacterium tuberculosis H37Rv (lab strain)}
872Rv0874chypothetical protein Rv0874c {Mycobacterium tuberculosis H37Rv (lab strain)}
873Rv0875chypothetical protein Rv0875c {Mycobacterium tuberculosis H37Rv (lab strain)}
874Rv0876chypothetical protein Rv0876c {Mycobacterium tuberculosis H37Rv (lab strain)}
875Rv0877hypothetical protein Rv0877 {Mycobacterium tuberculosis H37Rv (lab strain)}
876Rv0878c, (MTCY31.06c), len: 443, unknown; similar to YHS6_MYCTU P42611 hypothetical 50.6 kd protein in hsp65 3 region, (517 aa), FASTA scores: opt: 1044, z-score: 954.9, E(): 0, (47.4% identity in 397 aa overlap). Similar also to MTV014_3; MTCI65_2, MTCY98_24, M (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
877Rv0879chypothetical protein Rv0879c {Mycobacterium tuberculosis H37Rv (lab strain)}
878Rv0880hypothetical protein Rv0880 {Mycobacterium tuberculosis H37Rv (lab strain)}
879Rv0881hypothetical protein Rv0881 {Mycobacterium tuberculosis H37Rv (lab strain)}
880Rv0882hypothetical protein Rv0882 {Mycobacterium tuberculosis H37Rv (lab strain)}
881Rv0883chypothetical protein Rv0883c {Mycobacterium tuberculosis H37Rv (lab strain)}
882Rv0884c, (MTCY31.12c), probable phosphoserine aminotransferase, len: 376, similar to RABEPIP_1 Rabbit P10658|SERC_RABIT P10658 (370 aa). FASTA scores opt: 271 z-score: 318.3 E(): 3.5e-11; (24.5% identity in 368 aa overlap). Equivalent to MLCB57_17 Mycobacterium (serC) {Mycobacterium tuberculosis H37Rv (lab strain)}
883Rv0885hypothetical protein Rv0885 {Mycobacterium tuberculosis H37Rv (lab strain)}
884Rv0886, (MTCY31.14), len: 525 ferredoxin,fprB, PUTATIVE FERREDOXIN/FERREDOXIN--NADP REDUCTASE, similar to egADRO_HUMAN P22570 nadph:adrenodoxin oxidoreductase prec (497 aa)FASTA scores: opt: 624 z-score: 660.6 E(): 3e-30Smith-Waterman score: 997; 39.7% identity (fprB) {Mycobacterium tuberculosis H37Rv (lab strain)}
885Rv0887chypothetical protein Rv0887c {Mycobacterium tuberculosis H37Rv (lab strain)}
886Rv0888hypothetical protein Rv0888 {Mycobacterium tuberculosis H37Rv (lab strain)}
887Rv0889c, (MTCY31.17c), len: 373, citA, citrate synthase 2, similar to eg CISY_BACSU P39119 citrate synthase ii (ec 4.1.3.7 (366 aa) FASTA scores: opt: 586 z-score: 655.5 E(): 5.8e-30; (33.8% identity in 367 aa overlap); contains PS00480 Citrate synthase signatur (citA) {Mycobacterium tuberculosis H37Rv (lab strain)}
888Rv0890chypothetical protein Rv0890c {Mycobacterium tuberculosis H37Rv (lab strain)}
889Rv0891chypothetical protein Rv0891c {Mycobacterium tuberculosis H37Rv (lab strain)}
890Rv0892hypothetical protein Rv0892 {Mycobacterium tuberculosis H37Rv (lab strain)}
891Rv0893chypothetical protein Rv0893c {Mycobacterium tuberculosis H37Rv (lab strain)}
892Rv0894hypothetical protein Rv0894 {Mycobacterium tuberculosis H37Rv (lab strain)}
893Rv0895hypothetical protein Rv0895 {Mycobacterium tuberculosis H37Rv (lab strain)}
894Rv0896, (MTCY31.24), len: 431, gltA2, citrate synthase, similar to many, e.g. CGGLTG_1 C;glutamicum CISY_CORGLP42457 (437 aa), FASTA scores: opt: 1847 z-score: 2094.0 E(): 0; (63.0% identity in 433 aa overlap); contains PS00480Citrate synthase signature; simila (gltA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
895Rv0897chypothetical protein Rv0897c {Mycobacterium tuberculosis H37Rv (lab strain)}
896Rv0898chypothetical protein Rv0898c {Mycobacterium tuberculosis H37Rv (lab strain)}
897Rv0899, (MTCY31.27), len: 326. Similar to many members of the OMPA family of outer membrane proteins e.g. YIAD_ECOLI P37665 hypothetical 22.2 kd lipoprotein in b (219 aa), FASTA scores; opt: 296, z-score: 322.0 E(): 2.2e-11, 45.3% identity in 117 aa overlap; co (ompA) {Mycobacterium tuberculosis H37Rv (lab strain)}
898Rv0900hypothetical protein Rv0900 {Mycobacterium tuberculosis H37Rv (lab strain)}
899Rv0901hypothetical protein Rv0901 {Mycobacterium tuberculosis H37Rv (lab strain)}
900Rv0902chypothetical protein Rv0902c {Mycobacterium tuberculosis H37Rv (lab strain)}
901Rv0903chypothetical protein Rv0903c {Mycobacterium tuberculosis H37Rv (lab strain)}
902Rv0904c, (MTCY31.32c), accD3, len: 495. Similar to many acetyl-coenzyme a carboxylase carboxylase beta subunits, e.g. ACCD_MARPO P12217 (316 aa), FASTA scores opt: 519 z-score: 557.7 E():1.6e-24, 40.2% identity in 219aa overlap); aa 52-90, 111-310, 371-430 are h (accD3) {Mycobacterium tuberculosis H37Rv (lab strain)}
903Rv0905, (MTCY31.33), len: 243.echA6, Possible enoyl-coa hydratase similar to many e.g. ECHH_RHOCA P24162 enoyl-coa hydratase homolog (orf257). (257 aa) FATA scores opt: 404 z-score: 491.6 E():7.8e-21, 37.3% identity in 249aa overlap; highly similar to reading f (echA6) {Mycobacterium tuberculosis H37Rv (lab strain)}
904Rv0906hypothetical protein Rv0906 {Mycobacterium tuberculosis H37Rv (lab strain)}
905Rv0907hypothetical protein Rv0907 {Mycobacterium tuberculosis H37Rv (lab strain)}
906Rv0908, (MTCY21C12.02), len: 797. ctpE, Probable cation-transporting ATPase, similar to many e.g. ATCL_SYNP7 P37278cation-transporting atpase pacl (926 aa), fasta scores; opt: 257 z-score: 722.6 E(): 4.8e-33, 27.7% identity in 905 aaoverlap. Contains E1-E2 ATPa (ctpE) {Mycobacterium tuberculosis H37Rv (lab strain)}
907Rv0909hypothetical protein Rv0909 {Mycobacterium tuberculosis H37Rv (lab strain)}
908Rv0910hypothetical protein Rv0910 {Mycobacterium tuberculosis H37Rv (lab strain)}
909Rv0911hypothetical protein Rv0911 {Mycobacterium tuberculosis H37Rv (lab strain)}
910Rv0912hypothetical protein Rv0912 {Mycobacterium tuberculosis H37Rv (lab strain)}
911Rv0913chypothetical protein Rv0913c {Mycobacterium tuberculosis H37Rv (lab strain)}
912Rv0914chypothetical protein Rv0914c {Mycobacterium tuberculosis H37Rv (lab strain)}
913Rv0915c, (MTCY21C12.09c), len: 423; PPE-family protein, similar to many such as MTCY03A2.22c, 4e-27; MTCY03C7.24c, 5.5e-27; MTCY274.23c, 7.3e-27; MTCY98.0029c, 6.6e-23;MTCY02B10.25c, 5.2e-21; MTCY13E10.17c, 6.2e-21; MTCY31.06c,3.2e-20; MTCY03C7.23, 5.4e-20; MTCY (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
914Rv0916c, (MTCY21C12.10c), len: 99. PE-family protein, similar to many e.g. MTC1A11.04, 8.7e-10; MTCY359.33, 8.7e-10; MTCY98.0011c, 9.4e-10; MTCY270.06, 1.5e-09; MTCY21B4.13c, 2.8e-09; MTCY1A11.25c, 9.7e-09; MTCY06H11.11, 7.4e-08. FASTA best: Q50594 hypothetical (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
915Rv0917, (MTCY21C12.11), betP, len: 593. Similar toeg. BETP_CORGL P54582 glycine betaine transporter betp. cor(595 aa) opt: 1367 z-score: 1575.5 E(): 0; (42.7% identityin504 aa overlap) (betP) {Mycobacterium tuberculosis H37Rv (lab strain)}
916Rv0918hypothetical protein Rv0918 {Mycobacterium tuberculosis H37Rv (lab strain)}
917Rv0919hypothetical protein Rv0919 {Mycobacterium tuberculosis H37Rv (lab strain)}
918Rv0920chypothetical protein Rv0920c {Mycobacterium tuberculosis H37Rv (lab strain)}
919Rv0921hypothetical protein Rv0921 {Mycobacterium tuberculosis H37Rv (lab strain)}
920Rv0922hypothetical protein Rv0922 {Mycobacterium tuberculosis H37Rv (lab strain)}
921Rv0923chypothetical protein Rv0923c {Mycobacterium tuberculosis H37Rv (lab strain)}
922Rv0924c, (MTCY21C12.18c), len: 428. Probable transmembrane protein, similar to many members of the Nramp family. FASTA best: Q50103 M. leprae cosmid B650 (377 aa) opt: 1780 z-score: 2053.1 E(): 0; (74.5% identity in 376 aa overlap) (nramp) {Mycobacterium tuberculosis H37Rv (lab strain)}
923Rv0925chypothetical protein Rv0925c {Mycobacterium tuberculosis H37Rv (lab strain)}
924Rv0926chypothetical protein Rv0926c {Mycobacterium tuberculosis H37Rv (lab strain)}
925Rv0927chypothetical protein Rv0927c {Mycobacterium tuberculosis H37Rv (lab strain)}
926Rv0928, (MTCY21C12.22), phoS1/ag88, len: 370. Precursor of phosphate binding lipoprotein, PhoS, or antigen 88.Contains liporotein signature (PS00013) at N-terminus. FASTA best: Q50794 AG88 precursor (369 aa) opt: 2369 z-score:2541.4 E(): 0; Smith-Waterman score (phoS2) {Mycobacterium tuberculosis H37Rv (lab strain)}
927Rv0929, (MTCY21C12.23), pstC2, len: 324. Membrane-bound component of phosphate transport system. Contains binding-protein-dependent transport systems inner membrane component signature (PS00402). FASTA best: Q50797 PSTC-2.TUB. (323 aa) opt: 2002 z-score: 2368.0 (pstC2) {Mycobacterium tuberculosis H37Rv (lab strain)}
928Rv0930, (MTCY21C12.24), pstA1, len: 304. Membrane bound component of phosphate transport system. FASTA best: M. tuberculosis Q50795 PSTA-1 (304 aa) opt: 1624 z-score: 1945.9 E(): 0; (99.6% identity in 255 aa overlap) (pstA1) {Mycobacterium tuberculosis H37Rv (lab strain)}
929Rv0931c, (MTCY08D9.08), pknD, len: 664. Probable serine-threonine protein kinase. Related to many such proteinkinases particularly in N-terminal half. Fasta scores: Q11053 K08G_MYCTU PROBABLE SERINE/THREONINE-PROTEIN (626 aa) opt: 1398; E: 0; (49.3% identity in (pknD) {Mycobacterium tuberculosis H37Rv (lab strain)}
930Rv0932c, (MTCY08D9.07), pstS, len: 370. Probable precursor of PstS component of phosphate uptake system. Contains prokaryotic membrane lipoprotein lipid attachment site(PS00013) at N-terminus so leader peptide of 22 aa probablyremoved. M. tuberculosis seems to h (pstS) {Mycobacterium tuberculosis H37Rv (lab strain)}
931Rv0933, (MTCY08D9.06c), pstB, len: 276. Probable PstB, ABC transport component of phosphate uptake system. Contains PS00211 ABC transporters family signature (PS00211) and ATP/GTP-binding site motif A (P-loop; PS00017). Fasta scores: P46341 YQGJ_BACSU HYPOTHETI (pstB) {Mycobacterium tuberculosis H37Rv (lab strain)}
932Rv0934, (MTCY08D9.05c), phoS (pstS) len: 374. Precursor of PhoS (aka PAB, protein antigen B), mycobacterial equivalent of PstS component of phosphate uptake system. Contains prokaryotic membrane lipoprotein lipid attachment site(PS00013)at N-terminus so 23 aa l (phoS1) {Mycobacterium tuberculosis H37Rv (lab strain)}
933Rv0935, (MTCY08D9.04c), pstC, len: 338. Probable PstC component of phosphate uptake system. Contains binding-protein-dependent transport systems inner membrane comp signature (PS00402). fasta scores: P45191 PSTC_HAEIN PHOSPHATETRANSPORT SYSTEM permease (315 aa) (pstC) {Mycobacterium tuberculosis H37Rv (lab strain)}
934Rv0936, (MTCY08D9.03c), pstA, len: 301. Probable PstA component of phosphate uptake system. Contains binding-protein-dependent transport systems inner membrane comp signature (PS00402). fasta scores: P07654 PSTA_ECOLI PHOSPHATETRANSPORT SYSTEM PERMEASE (296 aa) (pstA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
935Rv0937chypothetical protein Rv0937c {Mycobacterium tuberculosis H37Rv (lab strain)}
936Rv0938hypothetical protein Rv0938 {Mycobacterium tuberculosis H37Rv (lab strain)}
937Rv0939hypothetical protein Rv0939 {Mycobacterium tuberculosis H37Rv (lab strain)}
938Rv0940chypothetical protein Rv0940c {Mycobacterium tuberculosis H37Rv (lab strain)}
939Rv0941chypothetical protein Rv0941c {Mycobacterium tuberculosis H37Rv (lab strain)}
940Rv0942hypothetical protein Rv0942 {Mycobacterium tuberculosis H37Rv (lab strain)}
941Rv0943chypothetical protein Rv0943c {Mycobacterium tuberculosis H37Rv (lab strain)}
942Rv0944hypothetical protein Rv0944 {Mycobacterium tuberculosis H37Rv (lab strain)}
943Rv0945hypothetical protein Rv0945 {Mycobacterium tuberculosis H37Rv (lab strain)}
944Rv0946c, (MTCY10D7.28), len: 553. Probable glucose-6-phosphate isomease, strong similarity to G6PI_ECOLI P11537 glucose-6-phosphate isomerase (gpi) (549 aa) fasta scoresopt: 1779, E(): 0, (51.4% identity in 554 aa overlap); contains PS00765 Phosphoglucose isomer (pgi) {Mycobacterium tuberculosis H37Rv (lab strain)}
945Rv0947chypothetical protein Rv0947c {Mycobacterium tuberculosis H37Rv (lab strain)}
946Rv0948chypothetical protein Rv0948c {Mycobacterium tuberculosis H37Rv (lab strain)}
947Rv0949, (MTCY10D7.25c), len: 771. Probable DNA helicase similar to many eg. YAY5_SCHPO Q10213 probable atp-dependent dna helicase c (887 aa), FASTA scores, opt: 927, z-score: 1046.0, E(): 0, (33.5% identity in 659 aa overlap); contains PS00017 ATP/GTP-binding s (uvrD) {Mycobacterium tuberculosis H37Rv (lab strain)}
948Rv0950chypothetical protein Rv0950c {Mycobacterium tuberculosis H37Rv (lab strain)}
949Rv0951, (MTCY10D7.23c), sucC, len: 387. Probable succinyl-coa synthetase similar to e.g. SUCC_ECOLI P07460 succinyl-coa synthetase beta chain (388 aa), FASTA scores, opt: 933, z-score: 1038.9 E(): 0, (41.0% identity in 390 aa overlap) (sucC) {Mycobacterium tuberculosis H37Rv (lab strain)}
950Rv0952, (MTCY10D7.22c), sucD, len: 303. Probable succinyl-coa synthetase alpha chain, similar to e.g. SUCD_ECOLI P07459 (288 aa), fasta scores, opt: 855, E(): 0, (53.8%identity in 286 aa overlap); contains PS00399 ATP-citrate lyase and succinyl-CoA ligases acti (sucD) {Mycobacterium tuberculosis H37Rv (lab strain)}
951Rv0953chypothetical protein Rv0953c {Mycobacterium tuberculosis H37Rv (lab strain)}
952Rv0954hypothetical protein Rv0954 {Mycobacterium tuberculosis H37Rv (lab strain)}
953Rv0955hypothetical protein Rv0955 {Mycobacterium tuberculosis H37Rv (lab strain)}
954Rv0956, (MTCY10D7.18c), purN, len: 215. Similar toPUR3_ECOLI P08179 phosphoribosylglycinamide formyltransferase (212 aa), fasta scores, opt: 380, E(): 2.4e-18, (36.6% identity in 183 aa overlap) (purN) {Mycobacterium tuberculosis H37Rv (lab strain)}
955Rv0957, (MTCY10D7.17c), purH, len: 523. Strong similarity to PUR9_ECOLI P15639 phosphoribosylaminoimidazolecarboxamide formyltransferase (529 aa), fasta scores, opt: 1147, E(): 0, (44.8% identity in 533 aa overlap) (purH) {Mycobacterium tuberculosis H37Rv (lab strain)}
956Rv0958hypothetical protein Rv0958 {Mycobacterium tuberculosis H37Rv (lab strain)}
957Rv0959hypothetical protein Rv0959 {Mycobacterium tuberculosis H37Rv (lab strain)}
958Rv0960hypothetical protein Rv0960 {Mycobacterium tuberculosis H37Rv (lab strain)}
959Rv0961hypothetical protein Rv0961 {Mycobacterium tuberculosis H37Rv (lab strain)}
960Rv0962chypothetical protein Rv0962c {Mycobacterium tuberculosis H37Rv (lab strain)}
961Rv0963chypothetical protein Rv0963c {Mycobacterium tuberculosis H37Rv (lab strain)}
962Rv0964chypothetical protein Rv0964c {Mycobacterium tuberculosis H37Rv (lab strain)}
963Rv0965chypothetical protein Rv0965c {Mycobacterium tuberculosis H37Rv (lab strain)}
964Rv0966chypothetical protein Rv0966c {Mycobacterium tuberculosis H37Rv (lab strain)}
965Rv0967hypothetical protein Rv0967 {Mycobacterium tuberculosis H37Rv (lab strain)}
966Rv0968hypothetical protein Rv0968 {Mycobacterium tuberculosis H37Rv (lab strain)}
967Rv0969, (MTCY10D7.05c), len: 770. ctpV, Probable cation transport atpase, similar to e.g. ATCS_SYNP7 P37279 cation-transporting atpase pacs (747 aa) opt: 1851, z-score: 1862.3, E(): 0, (52.1% identity in 664 aa overlap), PS00154E1-E2 ATPases phosphorylation sit (ctpV) {Mycobacterium tuberculosis H37Rv (lab strain)}
968Rv0970hypothetical protein Rv0970 {Mycobacterium tuberculosis H37Rv (lab strain)}
969Rv0971c, (MTCY10D7.03), len: 269. echA7, Probable enoyl-coA hydratase, similar to e.g. ECHH_RHOCA P24162 enoyl-coa hydratase homologue (orf257) (257 aa), FASTA scores, opt: 369, z-score: 399.8, E(): 2.6e-15, (33.7% identityin 246 aa overlap) (echA7) {Mycobacterium tuberculosis H37Rv (lab strain)}
970Rv0972c, (MTCY10D7.02), len: 388.fadE12, Probable acyl-coa dehydrogenase, similar to eg ACDB_BACSU P45857, (379 aa),FASTA scores, opt: 576, z-score: 598.1, E(): 2.3e-26, (29.7% identity in 381 aaoverlap (fadE12) {Mycobacterium tuberculosis H37Rv (lab strain)}
971Rv0973c, (MTV044.01c-MTCY10D7.01), len: 667,accA2, Probable carbamoyl-phosphate synthase, biotin dependent,similar to pyruvate- or urea- carboxylases, similar to many e.g. MTCY349_20. FASTA scores: gp|Z83018|MTCY349_20 M. tuberculosis cosmid (1127 aa) opt: 838 z (accA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
972Rv0974c, (MTV044.02c), len: 529. accD2, Probable propionyl-CoA carboxylase similar to many, e.g.gp|Y07660|MTACCBC_1M.tuberculosis accBC gene. B subun (522 aa) opt: 1350 z-score: 1579.2 E(): 0. 46.8% identity in 509 aa overlap. TBparse score is 0.875 (accD2) {Mycobacterium tuberculosis H37Rv (lab strain)}
973Rv0975c, (MTV044.03c), len: 382.fadE13, Probable Acyl-CoAdehydrogenase similar to many e.g.gp|M74096|HUMACADL_1 Human long chain acyl-CoA dehydro (430 aa) FASTA scores:opt: 819 z-score: 886.7 E(): 0. 37.0% identity in 376 aaoverlap or gp|Z98209|MTCY154_4 M. tube (fadE13) {Mycobacterium tuberculosis H37Rv (lab strain)}
974Rv0976chypothetical protein Rv0976c {Mycobacterium tuberculosis H37Rv (lab strain)}
975Rv0977, (MTV044.05), len: 923. Unknown glycine richprotein, similar to other PGRS-type sequences e.g. gp|AL0091|MTV004_1M. tuberculosis sequence (1125 aa), 45.4% identity in 959 aa overlap; or gp|Z80225|MTCY441_4 M. tuberculosiscosmid (778 aa), 51.5% identity i (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
976Rv0978c, (MTV044.06c), len: 331. Member of M. tuberculosis gly-, ala-, asn-rich protein family, pgrs family,similar to e.g. gp|Z95387|MTCY1A10_19 M. tuberculosis cosmi(461 aa).73.6% identity in 277 aa overlapscore is 0.861 (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
977Rv0979chypothetical protein Rv0979c {Mycobacterium tuberculosis H37Rv (lab strain)}
978Rv0980c, (MTV044.08c), len: 457. Member of M. tuberculosis gly-, ala-, asn-rich protein family, pgrs family. similar to many e.g. gp|Z95387|MTCY1A10_19 M. tuberculosis cosmi (461 aa), 66.7% identity in 405 aa overlap; or gp|Z95844|MTCY493_2M. tuberculosis cosmid (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
979Rv0981hypothetical protein Rv0981 {Mycobacterium tuberculosis H37Rv (lab strain)}
980Rv0982hypothetical protein Rv0982 {Mycobacterium tuberculosis H37Rv (lab strain)}
981Rv0983hypothetical protein Rv0983 {Mycobacterium tuberculosis H37Rv (lab strain)}
982Rv0984, (MTV044.12), moaB-2, len: 181. Putative molybdenum cofactor biosynthesis protein (moaB) similar to many e.g. gp|AF0082|AF008220_146 B. subtilis rrnB-dnaB gen (170 aa), FASTA scores; opt: 220 z-score: 283.0 E(): 2.9e-08. 33.1% identity in 172 aa overlap (moaB2) {Mycobacterium tuberculosis H37Rv (lab strain)}
983Rv0985c, (MTV044.13c), mscL, len: 151. Hypotheticalprotein highly similar to large-conductance mechanosensitive channel proteins, mechanosensitive channel activity of large conductance (mscL). e.g. gp|Z83337|BSZ83337_6 B.subtilis mbl, flh[O,P], rapD,(130 aa) FAS (mscL) {Mycobacterium tuberculosis H37Rv (lab strain)}
984Rv0986hypothetical protein Rv0986 {Mycobacterium tuberculosis H37Rv (lab strain)}
985Rv0987hypothetical protein Rv0987 {Mycobacterium tuberculosis H37Rv (lab strain)}
986Rv0988hypothetical protein Rv0988 {Mycobacterium tuberculosis H37Rv (lab strain)}
987Rv0989c, (MTCI237.03c), len: 325.grcC2, Probable transferase, isoprene biosynthesis, similar e.g. to HEP2_BACST P55785 heptaprenyl diphosphate synthase component (323 aa),fasta scores, opt: 496 z-score: 566.9 E(): 1.4e-24, (31.4%identity in 306 aa overlap) (grcC2) {Mycobacterium tuberculosis H37Rv (lab strain)}
988Rv0990chypothetical protein Rv0990c {Mycobacterium tuberculosis H37Rv (lab strain)}
989Rv0991chypothetical protein Rv0991c {Mycobacterium tuberculosis H37Rv (lab strain)}
990Rv0992chypothetical protein Rv0992c {Mycobacterium tuberculosis H37Rv (lab strain)}
991Rv0993, (MTCI237.07), galU, len: 306.galU, Probable utp--glucose-1-phosphate uridylyltransferase, similar toe.g. GALU_ECOLI P25520 utp--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (301 aa), fasta score, opt: 624 z-score: 724.3 E(): 2.4e-33, (38.8% iden (galU) {Mycobacterium tuberculosis H37Rv (lab strain)}
992Rv0994, (MTCI237.08), moeA, len: 426. Probable MoeAprotein, similar to e.g. MOEA_ECOLI P12281 molybdopterin biosynthesis moea protein (411 aa), fasta scores, opt: 519 z-score: 567.7 E(): 1.3e-24, (32.3% identity in 402 aa overlap) (moeA) {Mycobacterium tuberculosis H37Rv (lab strain)}
993Rv0995, (MTCI237.09), len: 203. Similar to eg RIMJ_ECOLI P09454 ribosomal-protein-alanine acetyltrans (194aa),fasta scores, opt: 247 z-score: 315.0 E(): 1.5e-10, (26.9%identity in 186 aa overlap) (rimJ) {Mycobacterium tuberculosis H37Rv (lab strain)}
994Rv0996hypothetical protein Rv0996 {Mycobacterium tuberculosis H37Rv (lab strain)}
995Rv0997hypothetical protein Rv0997 {Mycobacterium tuberculosis H37Rv (lab strain)}
996Rv0998hypothetical protein Rv0998 {Mycobacterium tuberculosis H37Rv (lab strain)}
997Rv0999hypothetical protein Rv0999 {Mycobacterium tuberculosis H37Rv (lab strain)}
998Rv1000hypothetical protein Rv1000 {Mycobacterium tuberculosis H37Rv (lab strain)}
999Rv1001, (MTCI237.16), arcA, len: 402. Probable arginine deiminase, similar to e.g. ARCA_PSEAE P13981 argininedeiminase (ec 3.5.3.6) (417 aa), fasta scores, opt:581 z-score: 692.9 E(): 1.4e-31, (39.4% identity in 411 aaoverlap),also similar to SAGP_STRPY P16962 (arcA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1000Rv1002chypothetical protein Rv1002c {Mycobacterium tuberculosis H37Rv (lab strain)}
1001Rv1003hypothetical protein Rv1003 {Mycobacterium tuberculosis H37Rv (lab strain)}
1002Rv1004chypothetical protein Rv1004c {Mycobacterium tuberculosis H37Rv (lab strain)}
1003Rv1005c, (MTCI237.22c), len: 458. Start-site not certain, similar to eg PABB_ECOLI P05041 para-aminobenzoate synthasecomponent I (EC 4.1.3.-) (453 aa), fasta scores, opt: 589z-score: 619.1 E(): 1.8e-27, (40.7% identity in 268 aa overlap) (pabB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1004Rv1006hypothetical protein Rv1006 {Mycobacterium tuberculosis H37Rv (lab strain)}
1005Rv1007c, (MTCI237.24), metS, len: 519. Probable methionyl-tra synthetase, similar to e.g. SYM_BACSU P37465 methionyl-trna synthetase (ec 6.1.1.10) (664 aa), fasta scores, opt: 1506 z-score: 1698.0 E(): 0, (44.9% identity in 492aa overlap); contains PS00178 Amino (metS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1006Rv1008hypothetical protein Rv1008 {Mycobacterium tuberculosis H37Rv (lab strain)}
1007Rv1009hypothetical protein Rv1009 {Mycobacterium tuberculosis H37Rv (lab strain)}
1008Rv1010, (MTCI237.27), ksgA, len:317. Probable dimethyladenosine transferase, similar to e.g. KSGA_BACSU P37468dimethyladenosine transferase (EC 2.1.1.-) (292 aa), fastascores, opt: 524 z-score: 638.1 E(): 1.5e-28, (37.2% identity in 274 aa overlap); contains PS (ksgA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1009Rv1011hypothetical protein Rv1011 {Mycobacterium tuberculosis H37Rv (lab strain)}
1010Rv1012hypothetical protein Rv1012 {Mycobacterium tuberculosis H37Rv (lab strain)}
1011Rv1013, (MTCI237.30-MTCY10G2.36c), len: 544. Possible polyketide synthase similar to many e.g. N-terminus of TR:Q50857 (EMBL:U24657) SAFRAMYCIN MX1 SYNTHETASE B (1770 aa), fasta scores; opt: 526 z-score: 588.7 E(): 1.4e-25. 29.3% identity in 542 aa overlap. Con (pks16) {Mycobacterium tuberculosis H37Rv (lab strain)}
1012Rv1014c, (MTCY10G2.35), pth, len: 191. Probable peptidyl-trna hydrolase, similar to eg PTH_ECOLI P23932 peptidyl-trna hydrolase (ec 3.1.1.29) (194 aa), fasta scores, opt: 472, E(): 2.3e-25, (39.6% identity in 187 aa overlap) (pth) {Mycobacterium tuberculosis H37Rv (lab strain)}
1013Rv1015c, (MTCY10G2.34), rplY, len: 215. Probable 50s ribosomal protein l25 similar to RL25_ECOLI P02426 50s ribosomal protein l25. escherichi (94 aa), fasta scores, opt:182, E(): 2.5e-05, (38.4% identity in 86 aa overlap) and toCTC_BACSU P14194 general stress pr (rplY) {Mycobacterium tuberculosis H37Rv (lab strain)}
1014Rv1016c, (MTCY10G2.33), len: 226. Probable lipoprotein, similar to several M. tuberculosis hyp[othetical proteins e.g. Y0H3_MYCTU P71697 cy21d4.03c (310 aa), fasta scores; opt: 329 z-score: 442.0 E(): 2e-17, 32.3% identity in 229 aa overlap; contains PS00013 Pro (lpqT) {Mycobacterium tuberculosis H37Rv (lab strain)}
1015Rv1017c, (MTCY10G2.32), prsA, len: 326. Probale ribose-phosphate pyrophosphokinase, similar to eg KPRS_ECOLI P08330 ribose-phosphate pyrophosphokinase (314 aa), fasta scores, opt: 826, E(): 0, (43.8% identity in 317 aa overlap);contains PS00103 Purine/pyrimidine (prsA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1016Rv1018c, (MTCY10G2.31), glmU, len: 495. Probable udp-n-acetylglucosamine pyrophosphorylase, similar to eg GCAD_BACSU P14192 udp-n-acetylglucosamine pyrophosphorylase (EC2.7.7.23) (456 aa), fasta scores, opt: 1150, E(): 0, (40.0%identity in 453 aa overlap) (glmU) {Mycobacterium tuberculosis H37Rv (lab strain)}
1017Rv1019hypothetical protein Rv1019 {Mycobacterium tuberculosis H37Rv (lab strain)}
1018Rv1020, (MTCY10G2.29c), mfd, len: 1234. Probable transcription-repair coupling factor similar to eg MFD_ECOLIP30958 transcription-repair coupling factor (1148 aa), fastascores, opt: 1900, E(): 0, (37.9% identity in 1107 aa overlap); contains (mfd) {Mycobacterium tuberculosis H37Rv (lab strain)}
1019Rv1021hypothetical protein Rv1021 {Mycobacterium tuberculosis H37Rv (lab strain)}
1020Rv1022, (MTCY10G2.27c), len: 243. Similar to M. tuberculosis hypothetical protein MTV006.02C, fasta scores; E(): 2.8e-18, 37.9% identity in 240 aa overlap contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site (lpqU) {Mycobacterium tuberculosis H37Rv (lab strain)}
1021Rv1023, (MTCY10G2.26c), eno, len: 429. Probable enolase, similar to eg ENO_ECOLI P08324 enolase (ec 4.2.1.11)(431 aa), fasta scores, opt: 1487, E(): 0, (55.5% identityin422 aa overlap) (eno) {Mycobacterium tuberculosis H37Rv (lab strain)}
1022Rv1024hypothetical protein Rv1024 {Mycobacterium tuberculosis H37Rv (lab strain)}
1023Rv1025hypothetical protein Rv1025 {Mycobacterium tuberculosis H37Rv (lab strain)}
1024Rv1026hypothetical protein Rv1026 {Mycobacterium tuberculosis H37Rv (lab strain)}
1025Rv1027c, (MTCY10G2.22), kdpE, len: 226. Probable regulatory protein KdpE similar to KDPE_ECOLI P21866 kdp operon transcriptional regulatory protein (225 aa), fasta scores, opt: 691, E(): 0, (47.8% identity in 224 aa overlap) (kdpE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1026Rv1028c, (MTCY10G2.21), kdpD, len: 860. Probable sensor protein kdpd similar to KDPD_ECOLI P21865 sensor protein kdpd (ec 2.7.3.-) (894 aa), fasta scores, opt: 1041, E(): 0, (32.3% identity in 888 aa overlap); contains PS00017 ATP/GTP-binding site motif A (kdpD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1027Rv1029, (MTCY10G2.20c), kdpA, len: 571. Probable potassium-transporting atpase a chain, similar to ATKA_ECOLIP03959 potassium-transporting atpase a chain (557 aa), fastascores,opt: 1763, E(): 0, (50.4% identity in 569 aa overlap) (kdpA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1028Rv1030, (MTCY10G2.19c), kdpB, len: 709. Probable potassium-transporting atpase b chain similar to ATKB_ECOLI P03960 potassium-transporting atpase b chain (682 aa), fastascores, opt: 1481, E(): 0, (63.4% identity in 686 aa overlap); PS00154 E1-E2 ATPases phospho (kdpB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1029Rv1031, (MTCY10G2.18c), kdpC, len: 189. Probable potassium-transporting atpase c chain, similar to ATKC_ECOLIP03961 potassium-transporting atpase c chain, (190 aa),fastascores, opt: 475, E(): 3.1e-24, (45.7% identity in 186 aaoverlap) (kdpC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1030Rv1032chypothetical protein Rv1032c {Mycobacterium tuberculosis H37Rv (lab strain)}
1031Rv1033chypothetical protein Rv1033c {Mycobacterium tuberculosis H37Rv (lab strain)}
1032Rv1034chypothetical protein Rv1034c {Mycobacterium tuberculosis H37Rv (lab strain)}
1033Rv1035chypothetical protein Rv1035c {Mycobacterium tuberculosis H37Rv (lab strain)}
1034Rv1036chypothetical protein Rv1036c {Mycobacterium tuberculosis H37Rv (lab strain)}
1035Rv1037chypothetical protein Rv1037c {Mycobacterium tuberculosis H37Rv (lab strain)}
1036Rv1038chypothetical protein Rv1038c {Mycobacterium tuberculosis H37Rv (lab strain)}
1037Rv1039c, (MTCY10G2.10), len: 391. belongs to the M.tuberculosis PPE family, most similar to eg Y07P_MYCTU Q11031 hypothetical 40.0 kd protein cy02b10. (396 aa), fasttascores, opt: 898, E(): 0, (42.7% identity in 398 aa overlap) (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1038Rv1040c, (MTCY10G2.09), len: 275. similar to the N-terminal region of the PE family of M. tuberculosis, similar to eg YW36_MYCTU Q10873 hypothetical 53.7kd protein cy39.36c (558 aa), fasta scores, opt: 378, E():1e-12, (36.6% identity in 279 aa overlap) (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1039Rv1041chypothetical protein Rv1041c {Mycobacterium tuberculosis H37Rv (lab strain)}
1040Rv1042chypothetical protein Rv1042c {Mycobacterium tuberculosis H37Rv (lab strain)}
1041Rv1043chypothetical protein Rv1043c {Mycobacterium tuberculosis H37Rv (lab strain)}
1042Rv1044hypothetical protein Rv1044 {Mycobacterium tuberculosis H37Rv (lab strain)}
1043Rv1045hypothetical protein Rv1045 {Mycobacterium tuberculosis H37Rv (lab strain)}
1044Rv1046chypothetical protein Rv1046c {Mycobacterium tuberculosis H37Rv (lab strain)}
1045Rv1047hypothetical protein Rv1047 {Mycobacterium tuberculosis H37Rv (lab strain)}
1046Rv1048chypothetical protein Rv1048c {Mycobacterium tuberculosis H37Rv (lab strain)}
1047Rv1049hypothetical protein Rv1049 {Mycobacterium tuberculosis H37Rv (lab strain)}
1048Rv1050hypothetical protein Rv1050 {Mycobacterium tuberculosis H37Rv (lab strain)}
1049Rv1051chypothetical protein Rv1051c {Mycobacterium tuberculosis H37Rv (lab strain)}
1050Rv1052hypothetical protein Rv1052 {Mycobacterium tuberculosis H37Rv (lab strain)}
1051Rv1053chypothetical protein Rv1053c {Mycobacterium tuberculosis H37Rv (lab strain)}
1052Rv1054hypothetical protein Rv1054 {Mycobacterium tuberculosis H37Rv (lab strain)}
1053Rv1055hypothetical protein Rv1055 {Mycobacterium tuberculosis H37Rv (lab strain)}
1054Rv1056hypothetical protein Rv1056 {Mycobacterium tuberculosis H37Rv (lab strain)}
1055Rv1057hypothetical protein Rv1057 {Mycobacterium tuberculosis H37Rv (lab strain)}
1056Rv1058, (MTV017.11), len: 543. Probable fatty acidCoA-ligase similar to MEDIUM-CHAIN-FATTY-ACID--COA LIGASE (546 aa) (EC6.2.1.-) and 4-COUMARATE-COA LIGASE (EC 6.2.1.12). ContainsPS00455 Putative AMP-binding domain signature. FASTA scores: sp|Q00594|ALKK_PSEOL (fadD14) {Mycobacterium tuberculosis H37Rv (lab strain)}
1057Rv1059hypothetical protein Rv1059 {Mycobacterium tuberculosis H37Rv (lab strain)}
1058Rv1060hypothetical protein Rv1060 {Mycobacterium tuberculosis H37Rv (lab strain)}
1059Rv1061hypothetical protein Rv1061 {Mycobacterium tuberculosis H37Rv (lab strain)}
1060Rv1062hypothetical protein Rv1062 {Mycobacterium tuberculosis H37Rv (lab strain)}
1061Rv1063chypothetical protein Rv1063c {Mycobacterium tuberculosis H37Rv (lab strain)}
1062Rv1064c, (MTV017.17c), len: 139. Unknown but probably lipoprotein. Has N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. TBparse score is 0.912 (lpqV) {Mycobacterium tuberculosis H37Rv (lab strain)}
1063Rv1065hypothetical protein Rv1065 {Mycobacterium tuberculosis H37Rv (lab strain)}
1064Rv1066hypothetical protein Rv1066 {Mycobacterium tuberculosis H37Rv (lab strain)}
1065Rv1067c, (MTV017.20c), len: 667. Member of M. tuberculosis PE-family, Gly-, Ala-rich PGRS subfamily. ContainsPS00583 pfkB family of carbohydrate kinases signature 1, probably fortuitous. FASTA scores: AL0091|MTV004_44 (731 aa)opt: 2227 z-score: 1261.4 E(): 0; 55 (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1066Rv1068c, (MTV017.21c), len: 463. Member of M. tuberculosis PE-family, Gly-, Ala-rich PGRS subfamily. FASTA scores: gp|Z80108|MTCY21B4_13 (576 aa) opt: 1689 z-score: 1003.3 E(): 0; 56.6% identity in 516 aa overlap. TBparse score is 0.849 (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1067Rv1069chypothetical protein Rv1069c {Mycobacterium tuberculosis H37Rv (lab strain)}
1068Rv1070c, (MTV017.23c), len: 257. echA8, Probable enoyl-CoA hydratase,equivalent to Mycobacterium leprae B1306.05c protein (257aa), very similar to Rhizobium melilotii enoyl-CoA hydrataseL39265|RHMRPST_2 (257 aa). Contains enoyl-CoA hydratase. FASTA scores: sptr| (echA8) {Mycobacterium tuberculosis H37Rv (lab strain)}
1069Rv1071c, (MTV017.24c), len: 345. echA9, Probable enoyl-CoA hydratase or crotonase equivalent to Mycobacterium lepraecosmid B1306.06c protein (345 aa), similar to many eukaryotic and prokaryotic enoyl-CoA hydratases e.g. C. elegans Q19278 (386). FASTA scores: Y13 (echA9) {Mycobacterium tuberculosis H37Rv (lab strain)}
1070Rv1072hypothetical protein Rv1072 {Mycobacterium tuberculosis H37Rv (lab strain)}
1071Rv1073hypothetical protein Rv1073 {Mycobacterium tuberculosis H37Rv (lab strain)}
1072Rv1074c, (MTV017.27c), len: 405. fadA3, Probable beta-ketoacyl CoA thiolase similar to many involved in beta-oxidation e.g. Escherichia coli X97452|ECPAA_12 (401 aa) and D90778_5 (401 aa), or Acinetobacter calcoaceticus ACCCAT_9 (401 aa). Contains PS00737 Thiola (fadA3) {Mycobacterium tuberculosis H37Rv (lab strain)}
1073Rv1075chypothetical protein Rv1075c {Mycobacterium tuberculosis H37Rv (lab strain)}
1074Rv1076, (MTV017.29), len: 297. Unknown but very similar to several Mycobacterium tuberculosis proteins e.g. MTCY13E12.41c (277 aa), and to esterases and lipases of around 300 aa e.g. Acinetobacter lwoffii esterase Q44087 (303).FASTA scores: Z95390|MTY13E12_40 ( (lipU) {Mycobacterium tuberculosis H37Rv (lab strain)}
1075Rv1077, (MTV017.30), cysM, len: 464. cysM2, Probable cystathionine beta-synthase similar throughout its lengthto many eukaryotic cystathionine beta-synthases, also similar inN-terminal domain (aa 1 - 330) to Mycobacterium tuberculosis CysK, MTCY98.03 (310 aa). (cysM2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1076Rv1078, (MTV017.31), pra, len: 240. Unknown but equivalent to M.leprae proline rich antigen (249 aa). FASTA scores: X65546|MLPRAG_1 M.leprae pra gene for proline rich antigen (249 aa) opt: 1162 z-score: 676.8 E(): 3.3e-30;64.8% identity in 253 aa overlap. TBpar (pra) {Mycobacterium tuberculosis H37Rv (lab strain)}
1077Rv1079, (MTV017.32), metB, len: 388. Probable cystathionine gamma-synthase similar to many. closest to M. leprae P46807|METB_MYCLE (388 aa). Contains PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. FASTAscores: sp|P46807|METB_MYCLE CYSTA (metB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1078Rv1080c, (MTV017.33c), greA, len: 164. Probable transcription elongation factor G similar to many e.g P21346|GREA_ECOLI (158 aa) closest to M. leprae P46808|GREA_MYCLE (202 aa). Contains two PS00829 and one PS00830 Prokaryotic transcriptionelongation factors sig (greA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1079Rv1081chypothetical protein Rv1081c {Mycobacterium tuberculosis H37Rv (lab strain)}
1080Rv1082hypothetical protein Rv1082 {Mycobacterium tuberculosis H37Rv (lab strain)}
1081Rv1083hypothetical protein Rv1083 {Mycobacterium tuberculosis H37Rv (lab strain)}
1082Rv1084hypothetical protein Rv1084 {Mycobacterium tuberculosis H37Rv (lab strain)}
1083Rv1085chypothetical protein Rv1085c {Mycobacterium tuberculosis H37Rv (lab strain)}
1084Rv1086hypothetical protein Rv1086 {Mycobacterium tuberculosis H37Rv (lab strain)}
1085Rv1087, (MTV017.40), len: 767. Member of M. tuberculosis PE family, Gly-, Ala-rich PGRS subfamily. Contains PS00583 pfkBfamily of carbohydrate kinases signature 1 near C-terminus.FASTA scores: sp|P71933|YQ04_MYCTU HYPOTHETICAL 63.1 KD GLYCINE-RICH (778 aa) opt: (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1086Rv1088, (MTV017.41), len: 144. Member of Mycobacterium tuberculosis PE family, similar to many others e.g. MTCI418B_6 (487 aa) except it appears to be frameshifted around codon 84. No error to account for frameshift could be found. FASTA scores: gp|Z96071|MTCI4 (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1087Rv1089Protein sequence is in conflict with the conceptual translation; Rv1089, (MTV017.42), len: 120. Partial orf that appears to be frameshifted continuation of MTV017.41. Sequencehas been checked and appears correct. FASTA scores: Z95555|MTCY06F7_4Mycobacteri (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1088Rv1090hypothetical protein Rv1090 {Mycobacterium tuberculosis H37Rv (lab strain)}
1089Rv1091, (MTV017.44), len: 853. Member of M. tuberculosis PE-family, Gly-, Ala-rich PGRS subfamily. FASTA scores: sptr|O06810|O06810 HYPOTHETICAL 107.4 KD PROTEIN. (1329aa) opt:2723 z-score: 1545.5 E(): 0; 52.6% identity in951 aa overlap. TBparse score is 0.859 (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1090Rv1092c, (MTV017.45c), coaA, len: 312. Probable pantothenate kinase similar to many e.g. P15044|COAA_ECOLI (316 aa). Contains PS00017 ATP/GTP-binding site motif A (P-loop). FASTA scores: sp|P15044|COAA_ECOLI PANTOTHENATE KINASE(EC 2.7.1.33) (316 aa) opt: 1079 z- (coaA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1091Rv1093, (MTV017.46), glyA, len: 426. Probable SERINE HYDROXYMETHYLTRANSFERASE (EC 2.1.2.1) similar to many, best with HYPHOMICROBIUM METHYLOVORUM P34895|GLYA_HYPME (434aa). FASTAscores: sp|P34895|GLYA_HYPME SERINE HYDROXYMETHYLTRANSFERASE (434 aa) opt: 1492 z-s (glyA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1092Rv1094, (MTV017.47), len: 275. desA2, Probable stearoyl-acyl carrier protein desaturase weakly similar to plant stearoyl-acyl carrier protein desaturases but very similar to Mycobacterium tuberculosis enzyme DES (338 aa) and to Mycobacterium leprae AadX (338 aa (desA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1093Rv1095, (MTV017.48), len: 433. Unknown but similarto many proteins described as PhoH-like, e.g.Bacillus subtilis BSZ97025_12 (442 aa) or M. tuberculosis O05830|PHOL_MYCTU (352 aa). Contains PS00017 ATP/GTP-binding site motif A(P-loop).FASTA scores: gp|Z97025|BS (phoH2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1094Rv1096hypothetical protein Rv1096 {Mycobacterium tuberculosis H37Rv (lab strain)}
1095Rv1097chypothetical protein Rv1097c {Mycobacterium tuberculosis H37Rv (lab strain)}
1096Rv1098c, (MTV017.51c), fum, len: 474. Probable fumarase, similar to many P14408|FUMH_RA (507 aa) or P05042|FUMC_ECOLI (467 aa). FASTA scores: sp|P14408|FUMH_RAT FUMARATEHYDRATASE, MITOCHONDRIAL PRECURSOR (507 aa) opt: 1427 z-score: 1659.8 E(): 0; 52.3% identity (fum) {Mycobacterium tuberculosis H37Rv (lab strain)}
1097Rv1099chypothetical protein Rv1099c {Mycobacterium tuberculosis H37Rv (lab strain)}
1098Rv1100hypothetical protein Rv1100 {Mycobacterium tuberculosis H37Rv (lab strain)}
1099Rv1101chypothetical protein Rv1101c {Mycobacterium tuberculosis H37Rv (lab strain)}
1100Rv1102chypothetical protein Rv1102c {Mycobacterium tuberculosis H37Rv (lab strain)}
1101Rv1103chypothetical protein Rv1103c {Mycobacterium tuberculosis H37Rv (lab strain)}
1102Rv1104hypothetical protein Rv1104 {Mycobacterium tuberculosis H37Rv (lab strain)}
1103Rv1105hypothetical protein Rv1105 {Mycobacterium tuberculosis H37Rv (lab strain)}
1104Rv1106chypothetical protein Rv1106c {Mycobacterium tuberculosis H37Rv (lab strain)}
1105Rv1107c, (MTV017.60c), xseB, len: 85. Probable exonuclease VII small subunit similar to those from H. influenzae (P43914|EX7S_HAEIN 84 aa) and E. coli (P22938|EX7S_ECOLI79 aa). FASTA scores: sp|P43914|EX7S_HAEIN EXODEOXYRIBONUCLEASE SMALLSUBUNI (84 aa) opt: 126 (xseB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1106Rv1108c, (MTV017.61c), xseA, len: 415. Probable exonuclease VII large subunit similar to those from E. coli (P04994|EX7L_ECOLI 456 aa), B. subtilis, H. influenzae and H.pylori. FASTA scores: sp|P04994|EX7L_ECOLI EXODEOXYRIBONUCLEASE LARGESUBUNI (456 aa) opt: 581 (xseA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1107Rv1109chypothetical protein Rv1109c {Mycobacterium tuberculosis H37Rv (lab strain)}
1108Rv1110, (MTV017.63), len: 335. Unknown but very similar to LytB proteins from many bacteria (appears to have N-terminal extension) e.g. sp|P22565|LYTB_ECOLI LYTB PROTEIN(316 aa). Also very similar to another LytB-like protein from M. tuberculosis MTV004.40c (32 (lytB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1109Rv1111chypothetical protein Rv1111c {Mycobacterium tuberculosis H37Rv (lab strain)}
1110Rv1112hypothetical protein Rv1112 {Mycobacterium tuberculosis H37Rv (lab strain)}
1111Rv1113hypothetical protein Rv1113 {Mycobacterium tuberculosis H37Rv (lab strain)}
1112Rv1114hypothetical protein Rv1114 {Mycobacterium tuberculosis H37Rv (lab strain)}
1113Rv1115hypothetical protein Rv1115 {Mycobacterium tuberculosis H37Rv (lab strain)}
1114Rv1116hypothetical protein Rv1116 {Mycobacterium tuberculosis H37Rv (lab strain)}
1115Rv1117hypothetical protein Rv1117 {Mycobacterium tuberculosis H37Rv (lab strain)}
1116Rv1118chypothetical protein Rv1118c {Mycobacterium tuberculosis H37Rv (lab strain)}
1117Rv1119chypothetical protein Rv1119c {Mycobacterium tuberculosis H37Rv (lab strain)}
1118Rv1120chypothetical protein Rv1120c {Mycobacterium tuberculosis H37Rv (lab strain)}
1119Rv1121, (MTCY22G8.10), zwf, len 466. Probable glucose-6-phosphate 1-dehydrogenase, highly similar to eg. G6PD_ECOLI P22992 glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) (491 aa), fasta scores; opt: 642 z-score: 767.5 E(): 0, 35.8% identityin 478 aa overlap (zwf) {Mycobacterium tuberculosis H37Rv (lab strain)}
1120Rv1122, (MTCY22G8.11), gnd2, len: 340. Probable 6-phosphogluconate dehydrogenase, decarboxylating, highly similar to eg. Q53917 6-PHOSPHOGLUCONATE DEHYDROGENASE (291 aa)from Streptomyces coelicolor, fasta scores; opt: 431 z-score: 492.0 E(): 2.2e-20, 44.5% iden (gnd2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1121Rv1123c, (MTCY22G8.12c), len: 302. bpoB, Some similarity to a range of enzymes including; DEH1_MORSP Q01398 haloacetatedehalogenase (294 aa), fasta scores; 64 opt: 201z-score: 241.0 E(): 2.1e-06, 35.8% identity in 134 aa overlap, and; BPA1_STRAU P33912 non-haem (bpoB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1122Rv1124, (MTCY22G8.13), len: 316. ephC, Similar to Q42566epoxide hydrolase (321 aa) from Arabidopsis thaliana, fastascores; opt: 298 z-score: 356.0 E(): 8.2e-13, 27.6% identity in 333 aa overlap. Similar to other M. tuberculosishydrolaseseg. MTCY09F9.26c (26.7% (ephC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1123Rv1125hypothetical protein Rv1125 {Mycobacterium tuberculosis H37Rv (lab strain)}
1124Rv1126chypothetical protein Rv1126c {Mycobacterium tuberculosis H37Rv (lab strain)}
1125Rv1127c, (MTCY22G8.16c), len: 490. Highly similar to N-terminus of eg. PODK_BACSY P22983 pyruvate, phosphate dikinase (839 aa), fasta scores; opt: 786 z-score: 880.2 E():0, 37.0% identity in 514 aa overlap (ppdK) {Mycobacterium tuberculosis H37Rv (lab strain)}
1126Rv1128chypothetical protein Rv1128c {Mycobacterium tuberculosis H37Rv (lab strain)}
1127Rv1129chypothetical protein Rv1129c {Mycobacterium tuberculosis H37Rv (lab strain)}
1128Rv1130hypothetical protein Rv1130 {Mycobacterium tuberculosis H37Rv (lab strain)}
1129Rv1131, (MTCY22G8.20), gltA1, len: 393. Probable citrate synthase, highly similar to eg.CISY_MYCSM P26491 citrate synthase (ec4.1.3.7) (375 aa), fasta scores; opt: 1942z-score: 2334.7E(): 0, 80.0% identity in 375 aa overlap; contains PS00480Citrate synthase sig (gltA1) {Mycobacterium tuberculosis H37Rv (lab strain)}
1130Rv1132hypothetical protein Rv1132 {Mycobacterium tuberculosis H37Rv (lab strain)}
1131Rv1133c, (MTC22G8.22), metE, len: 759. Probable 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase (methionine synthase, vitamin-B12 independent isozyme), highly similar to eg. METE_ECOLI P25665 5-methyltetrahydropteroyltriglutamate--homocyste (metE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1132Rv1134hypothetical protein Rv1134 {Mycobacterium tuberculosis H37Rv (lab strain)}
1133Rv1135c, (MTCI65.02c), len: 618. Member of Gly, AlaAsn,-rich family (PPE class). Similar to etc, MTCY98.0034c,MTCY03C7.23, MTCY13E10.17c, MTCY06H11.05, MTCY31.06c. FASTAscores: MTCY9824 NID: g1781238 - Mycobacterium tuberculosis (615 aa) opt: 2292; E(): 0; 59.6% (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1134Rv1136hypothetical protein Rv1136 {Mycobacterium tuberculosis H37Rv (lab strain)}
1135Rv1137chypothetical protein Rv1137c {Mycobacterium tuberculosis H37Rv (lab strain)}
1136Rv1138chypothetical protein Rv1138c {Mycobacterium tuberculosis H37Rv (lab strain)}
1137Rv1139chypothetical protein Rv1139c {Mycobacterium tuberculosis H37Rv (lab strain)}
1138Rv1140hypothetical protein Rv1140 {Mycobacterium tuberculosis H37Rv (lab strain)}
1139Rv1141c, (MTCI65.08c), len: 268. echA11, Similar toenoyl-CoA hydratases and naphthoate synthases. FASTA scores: D907776NID: g1742263 - Escherichia coli (262 aa) opt: 513; E():1e-25; 36.1% identity in 249 aa overlap. Also very similartoupstream ORF MTCI65.09c, (2 (echA11) {Mycobacterium tuberculosis H37Rv (lab strain)}
1140Rv1142c, (MTCI65.09c), len: 268. echA10, Similar toenoyl-CoAhydratases and naphthoate synthases. FASTA scores: D907776D90777 NID: g1742263 - Escherichia coli (262 aa)opt: 525; E(): 1.3e-26; 35.1% identity in 251 aa overlap.Highlysimilar to downstream ORF MTCI65. (echA10) {Mycobacterium tuberculosis H37Rv (lab strain)}
1141Rv1143, (MTCI65.10), len: 360. Strong similarity torat 2-arylpropionyl-CoA epimerase and some similarity alsoto L-carnitine dehydratase (EC 4.2.1.89). FASTA scores: RN2ARYLCO NID: g1552373 - Norway rat. (361 aa) opt: 1035; E():0; 47.2% identity in 339 aa overla (mcr) {Mycobacterium tuberculosis H37Rv (lab strain)}
1142Rv1144hypothetical protein Rv1144 {Mycobacterium tuberculosis H37Rv (lab strain)}
1143Rv1145hypothetical protein Rv1145 {Mycobacterium tuberculosis H37Rv (lab strain)}
1144Rv1146hypothetical protein Rv1146 {Mycobacterium tuberculosis H37Rv (lab strain)}
1145Rv1147hypothetical protein Rv1147 {Mycobacterium tuberculosis H37Rv (lab strain)}
1146Rv1148chypothetical protein Rv1148c {Mycobacterium tuberculosis H37Rv (lab strain)}
1147Rv1149hypothetical protein Rv1149 {Mycobacterium tuberculosis H37Rv (lab strain)}
1148Rv1150hypothetical protein Rv1150 {Mycobacterium tuberculosis H37Rv (lab strain)}
1149Rv1151chypothetical protein Rv1151c {Mycobacterium tuberculosis H37Rv (lab strain)}
1150Rv1152hypothetical protein Rv1152 {Mycobacterium tuberculosis H37Rv (lab strain)}
1151Rv1153c, (MTCI65.20c), len: 282. Similar to O-methyl transferase involved in tetracenomycin (polyketide) synthesis in Streptomyces glaucescens (EC 2.1.1.-). FASTA scores: TCMP_STRGA (P39887) TETRACENOMYCIN POLYKETIDE SYNTHESIS O-METHYLTRANSFERASE TCMPDE(270 aa) (omt) {Mycobacterium tuberculosis H37Rv (lab strain)}
1152Rv1154chypothetical protein Rv1154c {Mycobacterium tuberculosis H37Rv (lab strain)}
1153Rv1155hypothetical protein Rv1155 {Mycobacterium tuberculosis H37Rv (lab strain)}
1154Rv1156hypothetical protein Rv1156 {Mycobacterium tuberculosis H37Rv (lab strain)}
1155Rv1157chypothetical protein Rv1157c {Mycobacterium tuberculosis H37Rv (lab strain)}
1156Rv1158chypothetical protein Rv1158c {Mycobacterium tuberculosis H37Rv (lab strain)}
1157Rv1159hypothetical protein Rv1159 {Mycobacterium tuberculosis H37Rv (lab strain)}
1158Rv1160, (MTCI65.27), mutT, len: 141. Probable mutator MutT protein or homolog (7,8-dihydro-8-oxoguanine-triphosphatase) (8-OXO-DGTPASE) (EC 3.6.1.-). Is more similar toE. coli MutT homolog (D908197) than to E. coli MutT itself.Contains PS00893 mutT domain signa (mutT2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1159Rv1161, (MTCI65.28), narG, len: 1232. Probable respiratory nitrate reductase alpha subunit (EC 1.7.99.4). Contains prokaryotic molybdopterin oxidoreductase signatures 1and 2 (PS00551, PS00490). FASTA scores: NARG_BACSU NITRATEREDUCTASE ALPHA CHAIN (EC 1.7.9 (12 (narG) {Mycobacterium tuberculosis H37Rv (lab strain)}
1160Rv1162, (MTCI65.29), narH, len: 558. Probable respiratory nitrate reductase beta chain. Contains PS00190 cytochrome c family heme-binding site signature. FASTA scores: NARH_BACSU P42176 NITRATE REDUCTASE BETA CHAIN (EC 1.7.99.4)(487 aa) opt: 2049; E(): 0; 56.8% (narH) {Mycobacterium tuberculosis H37Rv (lab strain)}
1161Rv1163, (MTCI65.30), narJ, len: 201. Probable respiratory nitrate reductase delta chain (EC 1.7.99.4). FASTA scores: NARJ_BACSU NITRATE REDUCTASE DELTA CHAIN, P42178, (184 aa) opt: 254; E(): 1.9e-10; 31.8% identity in 179 aa overlap. Strong similarity to region (narJ) {Mycobacterium tuberculosis H37Rv (lab strain)}
1162Rv1164, (MTCI65.31), narI, len: 246. Probable respiratory nitrate reductase gamma chain (EC 1.7.99.4). FASTA scores: NARI_BACSU NITRATE REDUCTASE GAMMA CHAIN; P42177; (223 aa) opt: 652; E(): 0; Smith-Waterman score: 652; 41.6% identityin 221 aa overlap. Highly (narI) {Mycobacterium tuberculosis H37Rv (lab strain)}
1163Rv1165hypothetical protein Rv1165 {Mycobacterium tuberculosis H37Rv (lab strain)}
1164Rv1166, (MTV005.02), len: 670. Possible membrane protein, almost identical in part to M. tuberculosis gene fragment TR:G2384665 (EMBL:AF009358) ORFA2-898 (FRAGMENT) (59aa)(93.9% identity in 49 aa overlap) (Nano F.E., Doran J.L.,Treit J.D., Moran A.J.; Identific (lpqW) {Mycobacterium tuberculosis H37Rv (lab strain)}
1165Rv1167chypothetical protein Rv1167c {Mycobacterium tuberculosis H37Rv (lab strain)}
1166Rv1168c, (MTV005.04c), len: 346. Member of the M. tuberculosis PPE-family, similar to many eg. TR:E332789 (EMBL:Z98268) MTCI125.27C (385 aa), fasta scores; opt: 504 z-score: 780.2 E(): 0, 36.6% identity in 388 aa overlap (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1167Rv1169c, (MTV005.05c), len: 100. similar to the N-terminal region of the M. tuberculosis PE family of proteinseg. TR:O05297 (EMBL:Z93777) MTCI364.07 (99 aa), fasta scores; opt: 209 z-score: 407.6 E(): 1.6e-15, 37.4% identityin 99 aa overlap. Also simlar to the N (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1168Rv1170hypothetical protein Rv1170 {Mycobacterium tuberculosis H37Rv (lab strain)}
1169Rv1171hypothetical protein Rv1171 {Mycobacterium tuberculosis H37Rv (lab strain)}
1170Rv1172c, (MTV005.08c), len: 308. N-terminus is similar to the N-terminus of members of the M. tuberculosis PE family of proteins eg. TR:P71748 (EMBL:Z81368) MTCY253.25C (361 aa), fasta scores; opt: 483 z-score: 520.9 E(): 7.8e-22, 46.4% identity in 192 aa overla (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1171Rv1173hypothetical protein Rv1173 {Mycobacterium tuberculosis H37Rv (lab strain)}
1172Rv1174chypothetical protein Rv1174c {Mycobacterium tuberculosis H37Rv (lab strain)}
1173Rv1175c, (MTV005.11c), fadH, len: 674; Probable 2,4-dienoyl-coA reductase, highly similar to E. coli TR:G2584857 (EMBL:U93405) 2,4-DIENOYL-COA REDUCTASE (FADH) (672 aa), fasta scores; opt:2344 z-score: 2419.4 E(): 0, 53.1% identity in 671 aa overlap (fadH) {Mycobacterium tuberculosis H37Rv (lab strain)}
1174Rv1176chypothetical protein Rv1176c {Mycobacterium tuberculosis H37Rv (lab strain)}
1175Rv1177, (MTV005.13), len: 108. fdxC, Probable ferredoxin highly similar to many eg. FER_MYCSM P00215 ferredoxin from mycobacterium smegmatis (106 aa), fasta scores; opt:705z-score: 1155.0 E(): 0, 87.7% identity in 106 aa overlap. Contains PS00198 4Fe-4S ferredo (fdxC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1176Rv1178hypothetical protein Rv1178 {Mycobacterium tuberculosis H37Rv (lab strain)}
1177Rv1179chypothetical protein Rv1179c {Mycobacterium tuberculosis H37Rv (lab strain)}
1178Rv1180, (MTV005.16), len: 488. Probable polyketidesynthase beta-ketoacyl synthase domain, similar to the N-terminus of many polyketide synthases eg. MCAS_MYCBO Q02251 mycocerosicacid synthase from mycobacterium bovis (2110 aa),fasta scores; opt: 2115 z-score: 2 (pks3) {Mycobacterium tuberculosis H37Rv (lab strain)}
1179Rv1181, (MTV005.17), len: 1582. Probable polyketidesynthase, similar to many eg. MCAS_MYCBO Q02251 mycocerosicacid synthase from mycobacterium bovis (2110 aa), fasta scores; opt: 3518 z-score: 6207.2 E(): 0, 59.7% identity in1614 aaoverlap. Note that this simil (pks4) {Mycobacterium tuberculosis H37Rv (lab strain)}
1180Rv1182, (MTV005.18), len: 472. Similar to other Mycobacterial hypothetical proteins eg. TR:Q49618 (EMBL:U00010)B1170_C1_180 from M. leprae (471 aa), fasta scores; opt: 2526 z-score: 3476.5 E(): 0, 75.6% identity in 471 aa overlap (papA3) {Mycobacterium tuberculosis H37Rv (lab strain)}
1181Rv1183, (MTV005.19), len: 1002. Probable transmembrane protein, similar to many Mycobacterial hypothetical membrane proteins eg. TR:Q49619 (EMBL:U00010) B1170_C1_181 (1008 aa), fasta scores; opt: 4545 z-score: 5010.3 E(): 0, 70.6% identity in 978 aa overlap (mmpL10) {Mycobacterium tuberculosis H37Rv (lab strain)}
1182Rv1184chypothetical protein Rv1184c {Mycobacterium tuberculosis H37Rv (lab strain)}
1183Rv1185c, (MTV005.21c), len: 578. fadD21, Probable acyl-coAsynthase, similar to eg. TR:P71495 (EMBL:U75685) ACYL-COA SYNTHASE from Mycobacterium bovis (582 aa), fasta scores; opt: 2388 z-score: 2929.0 E(): 0, 61.8% identity in 579 aa overlap (fadD21) {Mycobacterium tuberculosis H37Rv (lab strain)}
1184Rv1186chypothetical protein Rv1186c {Mycobacterium tuberculosis H37Rv (lab strain)}
1185Rv1187, (MTV005.23), rocA, len: 543. Probable pyrroline-5-carboxylate dehydrogenase, similar to many eg. PUT2_HUMAN P30038 delta-1-pyrroline-5-carboxylate dehydrogenase (563 aa), fasta scores; opt: 1596 z-score: 1724.4 E():0, 46.0% identity in 531 aa overlap. C (rocA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1186Rv1188hypothetical protein Rv1188 {Mycobacterium tuberculosis H37Rv (lab strain)}
1187Rv1189, (MTV005.25-MTCI364.01), len: 290. Probablesigma factor, similar to eg. TR:O05767 (EMBL:U87307) extracytoplasmic function alternative sigma factor (sigE) fromM. smegmatis (204 aa), fasta scores; opt: 239 z-score: 301.4 E(): 1.3e-09, 32.9% identity in 167 (sigI) {Mycobacterium tuberculosis H37Rv (lab strain)}
1188Rv1190hypothetical protein Rv1190 {Mycobacterium tuberculosis H37Rv (lab strain)}
1189Rv1191hypothetical protein Rv1191 {Mycobacterium tuberculosis H37Rv (lab strain)}
1190Rv1192hypothetical protein Rv1192 {Mycobacterium tuberculosis H37Rv (lab strain)}
1191Rv1193, (MTCI364.05), len: 473aa,fadD36, highly similar to M. leprae Q50017 XCLC (476 aa), fasta scores, opt:2594, E(): 0, (81.3% identity in 476 aa overlap), similar to LCFA_ECOLI P29212 long-chain-fatty-acid--coa ligase (561aa), fasta scores,opt: 605, E(): 8. (fadD36) {Mycobacterium tuberculosis H37Rv (lab strain)}
1192Rv1194chypothetical protein Rv1194c {Mycobacterium tuberculosis H37Rv (lab strain)}
1193Rv1195, (MTCI364.07), len: 99. Highly similar to N-terminal region of M. tuberculosis PE family eg Y0DP_MYCTU Q50615 hypothetical glycine-rich 40.8 kd pro (498aa), fastascores, opt: 307, E(): 1.4e-12, (56.3% identityin 96 aa overlap), similar to MTCY21C12.10c ( (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1194Rv1196, (MTCI364.08), len: 391. Belongs to the PPEfamily of M. tuberculosis hypothetical proteins, highly similar to Y07P_MYCTU Q11031 hypothetical 40.0 kd protein cy02b10.25c (396aa), fasta scores, opt: 2124, E(): 0, (85.1% identity in 397 aa overlap) (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1195Rv1197hypothetical protein Rv1197 {Mycobacterium tuberculosis H37Rv (lab strain)}
1196Rv1198hypothetical protein Rv1198 {Mycobacterium tuberculosis H37Rv (lab strain)}
1197Rv1199chypothetical protein Rv1199c {Mycobacterium tuberculosis H37Rv (lab strain)}
1198Rv1200hypothetical protein Rv1200 {Mycobacterium tuberculosis H37Rv (lab strain)}
1199Rv1201chypothetical protein Rv1201c {Mycobacterium tuberculosis H37Rv (lab strain)}
1200Rv1202, (MTCI364.14), dapE, len: 354.dapE, Probable succinyl-diaminopimelate desuccinylase, similar to e.g. DAPE_CORGL Q59284 succinyl-diaminopimelate desuccinylase (369 aa), fasta scores, opt: 1301, E(): 0, (55.7% identity in 359 aa overlap), highly similar to (dapE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1201Rv1203chypothetical protein Rv1203c {Mycobacterium tuberculosis H37Rv (lab strain)}
1202Rv1204chypothetical protein Rv1204c {Mycobacterium tuberculosis H37Rv (lab strain)}
1203Rv1205hypothetical protein Rv1205 {Mycobacterium tuberculosis H37Rv (lab strain)}
1204Rv1206, (MTCI364.18), len: 597. fadD6, similar to eg mouse fatp Q60714 fatty acid transport protein (646 aa), fasta scores, opt:712, E(): 0, (36.8% identity in 600 aa overlap); contains PS00017 ATP/GTP-binding site motif A (P-loop), PS00455 Putative AMP-binding (fadD6) {Mycobacterium tuberculosis H37Rv (lab strain)}
1205Rv1207, (MTCI364.19), folP2, len: 318. Dihydropteroate synthase, similar to eg DHPS_ECOLI P26282 (ec 2.5.1.15)(282 aa), fasta scores, opt: 480, E(): 1.9e-22, (34.4% identity in 270 aa overlap); contains PS00792 dihydropteroate synthase signature 1, PS00793 dihy (folP2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1206Rv1208hypothetical protein Rv1208 {Mycobacterium tuberculosis H37Rv (lab strain)}
1207Rv1209hypothetical protein Rv1209 {Mycobacterium tuberculosis H37Rv (lab strain)}
1208Rv1210, (MTCI364.22), tagA, len: 204. Probable dna-3-methyladenine glycosidase I, similar eg to 3MG1_ECOLI P05100 dna-3-methyladenine glycosidase i (187 aa), fasta scores, opt: 530, E(): 1.3e-27, (44.2% identity in 190 aa overlap), similar to M. leprae Q49957 c (tagA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1209Rv1211hypothetical protein Rv1211 {Mycobacterium tuberculosis H37Rv (lab strain)}
1210Rv1212chypothetical protein Rv1212c {Mycobacterium tuberculosis H37Rv (lab strain)}
1211Rv1213, (MTCI364.25), glgC, len: 404. Probable glucose-1-phosphate adenylyltransferase, similar to eg GLGC_ECOLI P00584 glucose-1-phosphate adenylyltransferase (EC 2.7.7.27) (430 aa), fasta scores, opt: 1075, E(): 0, (40.3% identity in 407 aa overlap), highly s (glgC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1212Rv1214c, (MTCI364.26c), len: 110. Similar to N-terminal region of M. tuberculosis PE family), appears to be frameshifted just upstream of this sequence but sequence of this cosmid appears to be correct (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1213Rv1215chypothetical protein Rv1215c {Mycobacterium tuberculosis H37Rv (lab strain)}
1214Rv1216chypothetical protein Rv1216c {Mycobacterium tuberculosis H37Rv (lab strain)}
1215Rv1217chypothetical protein Rv1217c {Mycobacterium tuberculosis H37Rv (lab strain)}
1216Rv1218chypothetical protein Rv1218c {Mycobacterium tuberculosis H37Rv (lab strain)}
1217Rv1219chypothetical protein Rv1219c {Mycobacterium tuberculosis H37Rv (lab strain)}
1218Rv1220chypothetical protein Rv1220c {Mycobacterium tuberculosis H37Rv (lab strain)}
1219Rv1221, (MTCI61.04), sigE, len: 257. Alternative sigma factor of extracytoplasmic function (ECF) family, see Wu Q.L.,Kong D., Lam K., Husson R.N.; A Mycobacterial extracytoplasmic function sigma factor involved in survival following stress; J. Bacteriol. 179:29 (sigE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1220Rv1222hypothetical protein Rv1222 {Mycobacterium tuberculosis H37Rv (lab strain)}
1221Rv1223, (MTCI61.06), htrA, len: 549. DegP protease serine protease homolog, similar to many eg. HTRA_ECOLI P09376 protease do precursor (ec 3.4.21.-) (474 aa), fasta scores; opt:581 z-score: 605.2 E(): 9.1e-27, 36.3% identity in278 aa overlap. Identical to PID: (htrA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1222Rv1224hypothetical protein Rv1224 {Mycobacterium tuberculosis H37Rv (lab strain)}
1223Rv1225chypothetical protein Rv1225c {Mycobacterium tuberculosis H37Rv (lab strain)}
1224Rv1226chypothetical protein Rv1226c {Mycobacterium tuberculosis H37Rv (lab strain)}
1225Rv1227chypothetical protein Rv1227c {Mycobacterium tuberculosis H37Rv (lab strain)}
1226Rv1228, (MTCI61.11), len: 185. Unknown, contains possible signal sequence and appropriately positioned PS00013Prokaryotic membrane lipoprotein lipid attachment site (lpqX) {Mycobacterium tuberculosis H37Rv (lab strain)}
1227Rv1229c, (MTCI61.12c-MTV006.01c), len: 390. Memberof MRP/NBP35 FAMILY OF ATP-BINDING proteins of unknown function, similar to eg. MRP_ECOLI P21590 mrp protein. escherichiacoli (379 aa), fasta results; E(): 0, 34.1% identity in355 aa overlap. Contains PS00017 ATP (mrp) {Mycobacterium tuberculosis H37Rv (lab strain)}
1228Rv1230chypothetical protein Rv1230c {Mycobacterium tuberculosis H37Rv (lab strain)}
1229Rv1231chypothetical protein Rv1231c {Mycobacterium tuberculosis H37Rv (lab strain)}
1230Rv1232chypothetical protein Rv1232c {Mycobacterium tuberculosis H37Rv (lab strain)}
1231Rv1233chypothetical protein Rv1233c {Mycobacterium tuberculosis H37Rv (lab strain)}
1232Rv1234hypothetical protein Rv1234 {Mycobacterium tuberculosis H37Rv (lab strain)}
1233Rv1235, (MTV006.07), len: 468. Unknown lipoprotein highly similar to M. leprae protein u1756v (469 aa), possibly involved in sugar (e.g. maltose) uptake. FASTA scores:MLU1518034opt: 2442 E(): 0; (77.4% identity in 470 aa overlap). Similar to P18815|MALE_ENTAE M (lpqY) {Mycobacterium tuberculosis H37Rv (lab strain)}
1234Rv1236, (MTV006.08), len: 307. Unknown membrane protein probably involved in sugar transport, most similar toM. leprae protein designated malF, U15180|MLU1518035 (310 aa). Also similar to numerous bacterial sugar transport system components. FASTA scores: opt: (sugA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1235Rv1237, (MTV006.09), len: 274. Probable sugar (e.g.maltose) transport protein similar to numerous bacterial sugar transport protein. Most similar to M. leprae protein designated MalG (296 aa). FASTA scores: U15180|MLU1518036opt:1571E(): 0; (89.8% identity in 27 (sugB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1236Rv1238, (MTV006.10), len: 393. Unknown ABC transporter component of sugar uptake system. Highly similar to M.leprae protein designated ugpC (392 aa) in U15180. FASTA score: opt:2007 E(): 0; (79.9% identity in 389 aa overlap).Contains PS00017 ATP/GTP-binding sit (sugC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1237Rv1239c, (MTV006.11c), corA, len: 366. Unknown, possible magnesium and cobalt transport protein highly similarto M. leprae protein (373 aa) designated corA in U15180.FASTA scores: opt: 1985 E(): 0; (79.1% identity in 369 aa overlap). Also similar to various CorA (corA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1238Rv1240, (MTV006.12), mdh, len: 329. Malate dehydrogenase. Most similar to P50917|MDH_MYCLE MALATE DEHYDROGENASE (EC 1.1.1.37 (329 aa). FASTA scores: opt: 1887 E(): 0; (89.1% identity in 329 aa overlap). Contains PS00068 Malate dehydrogenase active site signatur (mdh) {Mycobacterium tuberculosis H37Rv (lab strain)}
1239Rv1241hypothetical protein Rv1241 {Mycobacterium tuberculosis H37Rv (lab strain)}
1240Rv1242hypothetical protein Rv1242 {Mycobacterium tuberculosis H37Rv (lab strain)}
1241Rv1243c, (MTV006.15c), len: 562. Unknown, member ofPE family of glycine-rich M. tuberculosis proteins, PGRS subfamily. TBparse score is 0.875 (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1242Rv1244, (MTV006.16), len: 286. Unknown lipoproteinequivalentto M. leprae protein u1756x (228 aa). FASTA scores: U15180|MLU1518042 opt: 1039 E(): 0; (72.5% identity in 229 aa overlap). Contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site. TBpa (lpqZ) {Mycobacterium tuberculosis H37Rv (lab strain)}
1243Rv1245chypothetical protein Rv1245c {Mycobacterium tuberculosis H37Rv (lab strain)}
1244Rv1246chypothetical protein Rv1246c {Mycobacterium tuberculosis H37Rv (lab strain)}
1245Rv1247chypothetical protein Rv1247c {Mycobacterium tuberculosis H37Rv (lab strain)}
1246Rv1248c, (MTV006.20c), odhA, len: 1214. 2-oxoglutarate dehydrogenase, highly similar to sevral but closest toCorynebacterium glutamicum enzyme D84102 (1257 aa). FASTA scores:opt: 4418, E(): 0; (59.4% identity in 1223 aa overlap). TBparse score is 0.882 (sucA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1247Rv1249chypothetical protein Rv1249c {Mycobacterium tuberculosis H37Rv (lab strain)}
1248Rv1250hypothetical protein Rv1250 {Mycobacterium tuberculosis H37Rv (lab strain)}
1249Rv1251chypothetical protein Rv1251c {Mycobacterium tuberculosis H37Rv (lab strain)}
1250Rv1252c, (MTCY50.30), len: 202. Unknown, some similarity to M. tuberculosis protein MTCY13E12.36C E(): 7e-05, 29.5% identity in 200 aa overlap. Contains possible N-terminal signal;sequence and appropriately positioned prokaryotic lipoprotein lipid attachment sit (lprE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1251Rv1253, (MTCY50.29c), len: 563. Dead box atp-dependent rna helicase, similar to eg DEAD_ECOLI P23304, (646 aa)FASTA scores, opt: 1490, z-score: 1605.7, E(): 0, (46.7% identity in578 aa overlap; contains PS00017 ATP/GTP-bindingsite motifA, PS00039 DEAD-box subfa (deaD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1252Rv1254hypothetical protein Rv1254 {Mycobacterium tuberculosis H37Rv (lab strain)}
1253Rv1255chypothetical protein Rv1255c {Mycobacterium tuberculosis H37Rv (lab strain)}
1254Rv1256chypothetical protein Rv1256c {Mycobacterium tuberculosis H37Rv (lab strain)}
1255Rv1257chypothetical protein Rv1257c {Mycobacterium tuberculosis H37Rv (lab strain)}
1256Rv1258chypothetical protein Rv1258c {Mycobacterium tuberculosis H37Rv (lab strain)}
1257Rv1259hypothetical protein Rv1259 {Mycobacterium tuberculosis H37Rv (lab strain)}
1258Rv1260hypothetical protein Rv1260 {Mycobacterium tuberculosis H37Rv (lab strain)}
1259Rv1261chypothetical protein Rv1261c {Mycobacterium tuberculosis H37Rv (lab strain)}
1260Rv1262chypothetical protein Rv1262c {Mycobacterium tuberculosis H37Rv (lab strain)}
1261Rv1263, (MTCY50.19c), len: 462. amiB2, Probable amidase, similar to G1001278 hypothetical 54.3 kDa protein (506aa) opt: 767, z-score: 839.9, E(): 7.6e-40, (32.8% identity in 461 aa overlap), also to G580673 rhodococcus enantioselective amidase gene (462aa) FAST (amiB2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1262Rv1264hypothetical protein Rv1264 {Mycobacterium tuberculosis H37Rv (lab strain)}
1263Rv1265hypothetical protein Rv1265 {Mycobacterium tuberculosis H37Rv (lab strain)}
1264Rv1266c, (MTCY50.16), len: 626. Probable serine/threonine-protein kinase, similar to eg PKN1_MYXXA P33973 pkn1(693 aa) FASTA scores, opt: 611, z-score: 386.3, E(): 1.4e-14, (29.7% identityin 492 aa overlap), contains PS00107 Protein kinases ATP-binding region si (pknH) {Mycobacterium tuberculosis H37Rv (lab strain)}
1265Rv1267c, (MTCY50.15), len: 388. Probable regulatoryprotein, similar to e.g. AFSR_STRCO P25941 regulatory protein afsr, streptomyces(993 aa) FASTA scores, opt: 489, z-score: 586.4, E(): 1e-25, (33.5% identity in 361 aa overlap) (embR) {Mycobacterium tuberculosis H37Rv (lab strain)}
1266Rv1268chypothetical protein Rv1268c {Mycobacterium tuberculosis H37Rv (lab strain)}
1267Rv1269chypothetical protein Rv1269c {Mycobacterium tuberculosis H37Rv (lab strain)}
1268Rv1270c, (MTCY50.12), len: 244. Similar to M. bovislipoprotein TR:O32852 (EMBL:AJ000500) 27 KDA LIPOPROTEIN (236 aa), fasta scores; E(): 5.2e-23, 35.1% identity in 245aaoverlap. Contains probable N-terminal signal sequence. (lprA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1269Rv1271chypothetical protein Rv1271c {Mycobacterium tuberculosis H37Rv (lab strain)}
1270Rv1272chypothetical protein Rv1272c {Mycobacterium tuberculosis H37Rv (lab strain)}
1271Rv1273chypothetical protein Rv1273c {Mycobacterium tuberculosis H37Rv (lab strain)}
1272Rv1274, (MTCY50.08c), len: 185. Unknown, contains possible N-terminal signal sequence and appropriately positioned prokaryotic lipoprotein lipid attachment site (PS00013). (lprB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1273Rv1275,(MTCY50.07c), len: 180. Unknown, contains possible N-terminal signal sequence and appropriately positioned prokaryotic lipoprotein lipid attachment site (PS00013). (lprC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1274Rv1276chypothetical protein Rv1276c {Mycobacterium tuberculosis H37Rv (lab strain)}
1275Rv1277hypothetical protein Rv1277 {Mycobacterium tuberculosis H37Rv (lab strain)}
1276Rv1278hypothetical protein Rv1278 {Mycobacterium tuberculosis H37Rv (lab strain)}
1277Rv1279hypothetical protein Rv1279 {Mycobacterium tuberculosis H37Rv (lab strain)}
1278Rv1280c, (MTCY50.02), len: 591. oppA, Some similarity to periplasmic solute binding proteins e.g. OPPA_SALTY P06202 periplasmic oligopeptide-binding protein (542 aa), fasta scores; E(): 5.1e-05, 22.1% identity in 458 aa overlap. Has possible N-terminal signal se (oppA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1279Rv1281c, (MTCY50.01), len: 612. oppD, Probable ABC-type peptide transport protein, similar to DPPD_BACSU P26905 dipeptide transport atp-binding protein (335 aa) FASTA scores,opt: 983, z-score: 1044.9, E(): 0, (48.6% identity in 319 aa overlap); contains 2 x PS00 (oppD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1280Rv1282c, (MTCY373.01c-MTCY3H3.01), len: 291. oppC, Probable peptide transport system permease, similar to e.g.OPPC_ECOLI P77664 oligopeptide transport system permeas (302 aa), fasta scores; E(): 4.6e-33, 40.7% identity in 275 aaoverlap (oppC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1281Rv1283c, (MTCY373.02c), len: 325. oppB, Probable peptidetransport system permease, similar to e.g. DPPB_ECOLIP37316 dipeptide transport system permease protein DPPB (339 aa)opt: 402, z-score: 480.1, E(): 3.4e-20, (31.0% identity in345 aa overlap); contains PS004 (oppB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1282Rv1284hypothetical protein Rv1284 {Mycobacterium tuberculosis H37Rv (lab strain)}
1283Rv1285, (MTCY373.04), cysD, len: 332. Probable sulfate adenylate transferase subunit 2, but homology suggestsstart sites at aa 24 or 28, similar to e.g. CYSD_ECOLI P21156 sulfate adenylate transferase subunit 2 (302 aa)FASTA score, opt: 973, z-score: 1187.4, E( (cysD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1284Rv1286, (MTCY373.05), cysN, len: 614. Probable sulfate adenylate transferase, similar to CYSN_ECOLI P23845 sulfate adenylate transferase subunit 1 (475 aa) FASTA scores,opt: 1291, z-score: 1404.0, E():0, (50.2% identity in 428aaoverlap); contains 2 x PS00017 AT (cysN) {Mycobacterium tuberculosis H37Rv (lab strain)}
1285Rv1287hypothetical protein Rv1287 {Mycobacterium tuberculosis H37Rv (lab strain)}
1286Rv1288hypothetical protein Rv1288 {Mycobacterium tuberculosis H37Rv (lab strain)}
1287Rv1289hypothetical protein Rv1289 {Mycobacterium tuberculosis H37Rv (lab strain)}
1288Rv1290chypothetical protein Rv1290c {Mycobacterium tuberculosis H37Rv (lab strain)}
1289Rv1291chypothetical protein Rv1291c {Mycobacterium tuberculosis H37Rv (lab strain)}
1290Rv1292, (MTCY373.12), argS, len: 550. argS, Arginyl-trnasynthetase, highly similar to SYR_MYCLE P45840 (550 aa) FASTA scores,opt: 3115 z-score: 3492.9 E(): 0, (84.9% identityin 550 aa overlap); contains PS00178 Aminoacyl-transfer RNAsynthetases class-I signatur (argS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1291Rv1293, (MTCY373.13), lysA, len: 447. diaminopimelate decarboxylase, almost identical to DCDA_MYCTU P31848; contains PS00878 Orn/DAP/Arg decarboxylases family 2 pyridoxal-P attachment site, PS00879 Orn/DAP/Arg decarboxylases family 2 signature 2 (lysA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1292Rv1294, (MTCY373.14), thrA, len: 441. Homoserine dehydrogenase, highly similar to DHOM_MYCLE P46806 (441 aa) FASTA scores, opt: 2437 z-score: 2693.7 E():0, (89.5% identity in 438 aa overlap); contains PS00017 ATP/GTP-binding site motif A;PS01042 Homoserine dehy (thrA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1293Rv1295, (MTCY373.15), thrC, len: 360. Threonine synthase, highly similar to THRC_MYCLE P45837 (360 aa) FASTA scores, opt: 2202 z-score: 2447.3 E(): 0, (93.9% identity in359 aa overlap); contains PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachme (thrC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1294Rv1296, (MTCY373.16), thrB, len: 316. Homoserine kinase, highly similar to KHSE_MYCLE P45836 (314 aa) FASTA scores, opt: 1657 z-score: 1867.2, E(): 0, (82.0% identity in311 aa overlap); contains PS00639 Eukaryotic thiol (cysteine) proteases histidine active sit (thrB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1295Rv1297, (MTCY373.17), rho, len: 602. transcriptiontermination factor rho, highly similar to many e.g. RHO_MYCLE P45835, transcription termination factor rho homologue (610 aa) FASTA scores, (81.5% identity in 612 aa overlap) (rho) {Mycobacterium tuberculosis H37Rv (lab strain)}
1296Rv1298, (MTCY373.18), rpmE, len: 80. 50s ribosomalprotein L31, highly similar to many e.g. RL31_MYCLE P4583450s ribosomal protein l31. (84 aa)FASTA scores, opt: 490 z-score: 620.0, E(): 5.5e-28, (89.6% identity in 77 aa overlap); contains PS01143 Ribosomal prot (rpmE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1297Rv1299, (MTCY373.19), prfA, len: 357, peptide chainrelease factor 1 (rf-1), highly similar to many e.g. RF1_MYCLE P45833 peptide chain release factor 1 (rf-1), (357 aa)FASTA scores, opt: 2047 z-score: 2335.9 E(): 0, (89.3% identity in 356 aa overlap); PS00745 P (prfA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1298Rv1300, (MTCY373.20), hemK, len: 325. possible protoporphyrinogen oxidase, homology suggests translation startat aa 22, highly similar to many e.g. HEMK_MYCLE P45832 (191 aa) FASTA scores, opt: 936, z-score: 1095.9, E(): 0, (76.7% identity in 189 aa overlap) (hemK) {Mycobacterium tuberculosis H37Rv (lab strain)}
1299Rv1301hypothetical protein Rv1301 {Mycobacterium tuberculosis H37Rv (lab strain)}
1300Rv1302, (MTCY373.22), rfe, len: 404. putative undecaprenyl-phosphate alpha-n-acetylglucosaminyltransferase, highly similar to RFE_MYCLE P45830, (398 aa) FASTA scores, opt: 2285 z-score: 2679.7, E(): 0,(89.2% identity in 398 aa overlap) (rfe) {Mycobacterium tuberculosis H37Rv (lab strain)}
1301Rv1303hypothetical protein Rv1303 {Mycobacterium tuberculosis H37Rv (lab strain)}
1302Rv1304, (MTCY373.24), len: 250, atpB, ATP synthaseachain, highly similar to ATP6_MYCLE P45829, (251 aa), FASTAscores,opt: 1382 z-score: 1723.6 E(): 0, (84.0% identityin250 aaoverlap); contains PS00449 ATP synthase a subunitsignature (atpB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1303Rv1305, (MTCY373.25), len: 95. atpE, ATP synthase cchain, highly similar to (92.6% identity in 81 aa overlap); contains PS00605 ATP synthase c subunit signature (atpE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1304Rv1306, (MTCY373.26), len: 171. atpF, ATP synthase b chain, highly similar to ATPF_MYCLE P45827 (170 aa), FASTA scores, opt: 802, z-score: 919.7, E(): 0, (79.5% identityin 171 aaoverlap) (atpF) {Mycobacterium tuberculosis H37Rv (lab strain)}
1305Rv1307, (MTCY373.27), len: 446. atpH, Similarity toatp synthase b (5) and delta chains (3), eg ATPD_STRLI P50008 atp synthase delta chain (273 aa) FASTA scores, opt:505 z-score: 530.4, E(): 5.4e-23, (35.0% identity in 277 aaoverlap) and ATPF_HAEIN P43720 atp sy (atpH) {Mycobacterium tuberculosis H37Rv (lab strain)}
1306Rv1308, (MTCY373.28), len: 549. atpA, ATP synthasealpha chain, highly similar to ATPA_MYCLE P45825, (558 aa),FASTA scores, opt: 3233, z-score: 3587.5, E(): 0, (90.3% identity in547 aa overlap); contains PS00017 ATP/GTP-bindingsite motif A, PS00152 ATP synthase (atpA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1307Rv1309, (MTCY373.29), atpG, len: 305. ATP synthasegamma chain, highly similar toATPG_MYCLE P45824, atp synthase gamma chain, (298 aa) FASTA scores, opt: 1579 z-score: 1915.9 E():0, (83.9% identity in 305 aa overlap); contains PS00153 ATPsynthase gamma subunit s (atpG) {Mycobacterium tuberculosis H37Rv (lab strain)}
1308Rv1310, (MTCY373.30), atpD, len: 486. ATP synthasebeta chain, highly similar toATPB_MYCLE P45823 (485 aa) FASTA scores,opt: 2916, z-score: 3260.6, E(): 0, (92.6% identity in 484aa overlap); contains PS00017 ATP/GTP-binding sitemotif A, PS00152 ATP synthase alph (atpD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1309Rv1311, (MTCY373.31), atpC, len: 121. ATP synthaseepsilon chain, highly similar to ATPE_MYCLE P45822, (124 aa)FASTA scores, opt: 682, z-score: 835.9, E(): 5.4e-40, (87.6% identity in 121 aa overlap) (atpC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1310Rv1312hypothetical protein Rv1312 {Mycobacterium tuberculosis H37Rv (lab strain)}
1311Rv1313chypothetical protein Rv1313c {Mycobacterium tuberculosis H37Rv (lab strain)}
1312Rv1314chypothetical protein Rv1314c {Mycobacterium tuberculosis H37Rv (lab strain)}
1313Rv1315, (MTCY373.35-MTCY149.01), murA, len: 418. UDP-N-acetylglucosamine 1-carboxyvinyltransferase, highly similar to many e.g. MURA_MYCLE P45821 (418 aa) FASTA scores,opt: 2495, z-score: 2937.8, E(): 0, (96.2% identity in 396aaoverlap). (murA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1314Rv1316c, (MTCY130.01c), ogt, len: 165. Probable methylated-dna--protein-cysteine methytransferase similar to many e.g. OGT_HAEIN P44687 methylated-dna--protein-cysteinemethytransferase (190 aa) FASTA scores, opt: 405, z-score:475.1, E(): 6.5e-20, (41.9% identity (ogt) {Mycobacterium tuberculosis H37Rv (lab strain)}
1315Rv1317c, (MTCY130.02c), len: 496. alkA, similarity to 3MG2_ECOLI P04395 dna-3-methyladenine glycosidase ii, (282 aa), FASTA scores, opt: 437, z-score: 508.8, E(): 8.6e-22, (32.8% identity in 293 aa overlap), also similar to ada proteins e.g. ADA_SALTY P26189 ada (alkA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1316Rv1318chypothetical protein Rv1318c {Mycobacterium tuberculosis H37Rv (lab strain)}
1317Rv1319chypothetical protein Rv1319c {Mycobacterium tuberculosis H37Rv (lab strain)}
1318Rv1320chypothetical protein Rv1320c {Mycobacterium tuberculosis H37Rv (lab strain)}
1319Rv1321hypothetical protein Rv1321 {Mycobacterium tuberculosis H37Rv (lab strain)}
1320Rv1322hypothetical protein Rv1322 {Mycobacterium tuberculosis H37Rv (lab strain)}
1321Rv1323, (MTCY130.08), len: 389. fadA4, Acetyl-coa acetyltransferase, highly similar to THIL_MYCLE P46707 (393 aa) FASTA scores,opt: 2218, z-score: 2528.0, E(): 0, (87.0%identity in 392aa overlap), some homologies indicate ata start codon at 13165; contains PS00 (fadA4) {Mycobacterium tuberculosis H37Rv (lab strain)}
1322Rv1324hypothetical protein Rv1324 {Mycobacterium tuberculosis H37Rv (lab strain)}
1323Rv1325c, (MTCY130.10c), len: 603. Member of the PGRS Gly- Ala- rich subfamily of the PE family of proteins, similar to many e.g. YQ04_MYCTU P71933 hypothetical 63.1 kd glycine-rich protein (778 aa), fasta scores; E(): 0, 52.3% identity in 724 aa overlap (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1324Rv1326c, (MTCY130.11c), glgB, len: 731. 1,4-alpha-glucan branching enzyme, similar to e.g. GLGB_ECOLI P07762,(728 aa) FASTA scores, opt: 2330, z-score: 2726.7, E(): 0,(48.7% identity in 719 aa overlap) (glgB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1325Rv1327chypothetical protein Rv1327c {Mycobacterium tuberculosis H37Rv (lab strain)}
1326Rv1328, (MTCY130.13), glgP, len: 863. Probable glycogen phosphorylase, similar to many e.g. PHSG_HAEIN P45180glycogen phosphorylase (ec 2.4.1.1) (821 aa), fasta scores;E(): 6.9e-08, 25.6% identity in 675 aa overlap (glgP) {Mycobacterium tuberculosis H37Rv (lab strain)}
1327Rv1329c, (MTCY130.14c), dinG, len: 664. Probable atp-dependenthelicase dinG, similar to e.g. DING_HAEIN P44680probable atp-dependent helicase ding (640 aa) FASTA scores,opt: 685, z-score: 806.3, E(): 2.3e-38, (32.8% identity in644 aa overlap); contains PS00017 A (dinG) {Mycobacterium tuberculosis H37Rv (lab strain)}
1328Rv1330chypothetical protein Rv1330c {Mycobacterium tuberculosis H37Rv (lab strain)}
1329Rv1331hypothetical protein Rv1331 {Mycobacterium tuberculosis H37Rv (lab strain)}
1330Rv1332hypothetical protein Rv1332 {Mycobacterium tuberculosis H37Rv (lab strain)}
1331Rv1333hypothetical protein Rv1333 {Mycobacterium tuberculosis H37Rv (lab strain)}
1332Rv1334hypothetical protein Rv1334 {Mycobacterium tuberculosis H37Rv (lab strain)}
1333Rv1335hypothetical protein Rv1335 {Mycobacterium tuberculosis H37Rv (lab strain)}
1334Rv1336, (MTCY130.21), cysM, len: 323. Probable cysteine synthase b, similar to e.g. CYSM_ECOLI P16703,(303 aa)FASTA scores, opt: 720, z-score: 837.5, E(): 4.6e-40, (41.1% identity in 302 aaoverlap); contains PS00901 Cysteine synthase/cystathioninebeta-synthase (cysM) {Mycobacterium tuberculosis H37Rv (lab strain)}
1335Rv1337hypothetical protein Rv1337 {Mycobacterium tuberculosis H37Rv (lab strain)}
1336Rv1338, (MTCY130.23), len: 271.murI, Probable glutamateracemase, highly similar to many e.g MURI_MYCLE P46705(272aa) FASTA scores, opt: 1559 z-score: 1827.1 E(): 0, (88.9%identity in 271 aa overlap); contains PS00924 Aspartateand glutamate racemases signature 2 (murI) {Mycobacterium tuberculosis H37Rv (lab strain)}
1337Rv1339hypothetical protein Rv1339 {Mycobacterium tuberculosis H37Rv (lab strain)}
1338Rv1340, (MTCY130.25), rphA, len: 259. Ribonuclease ph, highly similar to e.g. RNPH_MYCLE P37939 (259 aa) FASTAscores, opt: 1524, z-score: 1739.7, E(): 0, (88.8% identityin 259 aa overlap) (rphA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1339Rv1341hypothetical protein Rv1341 {Mycobacterium tuberculosis H37Rv (lab strain)}
1340Rv1342c, (MTCY02B10.06c), len: 120. Highly similarto G466926 B1549_F2_59, (119 aa) FASTA scores, opt: 544, z-score: 653.4, E(): 1.9e-29, (68.3% identity in 120 aa overlap) (pks14) {Mycobacterium tuberculosis H37Rv (lab strain)}
1341Rv1343chypothetical protein Rv1343c {Mycobacterium tuberculosis H37Rv (lab strain)}
1342Rv1344hypothetical protein Rv1344 {Mycobacterium tuberculosis H37Rv (lab strain)}
1343Rv1345, (MTCY02B10.09), len: 521. fadD33, Probable polyketide synthase, similar to e.g. PKSJ_BACSU P40806 putative polyketide biosynthesis protein (557 aa) FASTA scores,opt: 537, z-score: 606.0, E(): 8.2e-27, (27.1% identity in468 aa overlap) (fadD33) {Mycobacterium tuberculosis H37Rv (lab strain)}
1344Rv1346, (MTCY02B10.10), len: 386.fadE14, Some similarity to ACDL_RATP15650 acyl-coa dehydrogenase, long-chainspecific (430 aa)FASTA scores, opt: 414, z-score: 459.3, E(): 1.2e-18, (26.1% identity in 376 aa overlap) (fadE14) {Mycobacterium tuberculosis H37Rv (lab strain)}
1345Rv1347chypothetical protein Rv1347c {Mycobacterium tuberculosis H37Rv (lab strain)}
1346Rv1348hypothetical protein Rv1348 {Mycobacterium tuberculosis H37Rv (lab strain)}
1347Rv1349hypothetical protein Rv1349 {Mycobacterium tuberculosis H37Rv (lab strain)}
1348Rv1350, (MTCY02B10.14), len: 247. fabG2, Oxidoreductase, most similar to G1118145 C. elegans (255 aa) opt: 641, z-score: 727.6, E(): 1.4e-33, (44.9% identity in 234 aa overlap); contains PS00061 Short-chain alcohol dehydrogenase family signature (fabG2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1349Rv1351hypothetical protein Rv1351 {Mycobacterium tuberculosis H37Rv (lab strain)}
1350Rv1352hypothetical protein Rv1352 {Mycobacterium tuberculosis H37Rv (lab strain)}
1351Rv1353chypothetical protein Rv1353c {Mycobacterium tuberculosis H37Rv (lab strain)}
1352Rv1354chypothetical protein Rv1354c {Mycobacterium tuberculosis H37Rv (lab strain)}
1353Rv1355c, (MTCY02B10.19c), len: 715. Unknown, but very weak similarity to MOEB_ECOLI P12282 molybdopterin biosynthesis moeb protein (249 aa) FASTA scores, opt: 180, z-score: 210.7, E(): 8.5e-05, (29.3% identity in 174 aa overlap) (moeY) {Mycobacterium tuberculosis H37Rv (lab strain)}
1354Rv1356chypothetical protein Rv1356c {Mycobacterium tuberculosis H37Rv (lab strain)}
1355Rv1357chypothetical protein Rv1357c {Mycobacterium tuberculosis H37Rv (lab strain)}
1356Rv1358hypothetical protein Rv1358 {Mycobacterium tuberculosis H37Rv (lab strain)}
1357Rv1359hypothetical protein Rv1359 {Mycobacterium tuberculosis H37Rv (lab strain)}
1358Rv1360hypothetical protein Rv1360 {Mycobacterium tuberculosis H37Rv (lab strain)}
1359Rv1361c, (MTCY02B10.25c), len: 396. Member of the PPE family of proteins, similar to e.g. MTCI364.08, fasta scores; E(): 0, 84.9% identity in 397 aa overlap; contains PS00501 Signal peptidases I serine active site; also similarto MTCY274.23c (42.3% identity in 4 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1360Rv1362chypothetical protein Rv1362c {Mycobacterium tuberculosis H37Rv (lab strain)}
1361Rv1363chypothetical protein Rv1363c {Mycobacterium tuberculosis H37Rv (lab strain)}
1362Rv1364c, (MTCY02B10.28c), len: 653. Unknown, some similarity to RSBU_BACSU P40399 sigma factor sibg regulationprotein, (335 aa), FASTA scores, opt: 224, z-score: 257.8,E(): 2e-07, (25.8% identity in 244 aa overlap) (rsbU) {Mycobacterium tuberculosis H37Rv (lab strain)}
1363Rv1365chypothetical protein Rv1365c {Mycobacterium tuberculosis H37Rv (lab strain)}
1364Rv1366hypothetical protein Rv1366 {Mycobacterium tuberculosis H37Rv (lab strain)}
1365Rv1367chypothetical protein Rv1367c {Mycobacterium tuberculosis H37Rv (lab strain)}
1366Rv1368, (MTCY02B12.02), len: 261. Similar to Y08C_MYCTU Q11049 hypothetical 26.4 kd protein cy50.12. (257 aa),fasta scores, opt: 286, E(): 5.3e-11, (26.3% identity in 270 aa overlap), also MTCY21B4.28c, (32.8% identity in 253 aaoverlap). Contains possible N-ter (lprF) {Mycobacterium tuberculosis H37Rv (lab strain)}
1367Rv1369chypothetical protein Rv1369c {Mycobacterium tuberculosis H37Rv (lab strain)}
1368Rv1370chypothetical protein Rv1370c {Mycobacterium tuberculosis H37Rv (lab strain)}
1369Rv1371hypothetical protein Rv1371 {Mycobacterium tuberculosis H37Rv (lab strain)}
1370Rv1372, (MTCY02B12.06), len: 393. Similar to e.g. CHS2_GERHY P48391 chalcone synthase 2 (402 aa)initn: 279 init1: 139 opt: 511 z-score: 590.4 E(): 7e-26, (28.4% identity in 380 aa overlap) (pks18) {Mycobacterium tuberculosis H37Rv (lab strain)}
1371Rv1373hypothetical protein Rv1373 {Mycobacterium tuberculosis H37Rv (lab strain)}
1372Rv1374chypothetical protein Rv1374c {Mycobacterium tuberculosis H37Rv (lab strain)}
1373Rv1375hypothetical protein Rv1375 {Mycobacterium tuberculosis H37Rv (lab strain)}
1374Rv1376hypothetical protein Rv1376 {Mycobacterium tuberculosis H37Rv (lab strain)}
1375Rv1377chypothetical protein Rv1377c {Mycobacterium tuberculosis H37Rv (lab strain)}
1376Rv1378chypothetical protein Rv1378c {Mycobacterium tuberculosis H37Rv (lab strain)}
1377Rv1379, (MTCY02B12.13), pyrR, len: 193. Probable pyrimidine operon regulatory protein similar to PYRR_BACCL P41007 pyrimidine operon regulatory protein (179 aa), fasta scores, opt: 544, E(): 1.1e-30, (54.2% identity in 179 aa overlap) (pyrR) {Mycobacterium tuberculosis H37Rv (lab strain)}
1378Rv1380, (MTCY02B12.14), pyrB, len: 319. Probable aspartate carbamoyltransferase similar to eg PYRB_BACCL P41008 aspartate carbamoyltransferase (308 aa), fasta scores, opt: 639, E(): 7.3e-36, (39.5% identity in 311 aa overlap); contains PS00097 Aspartate and orn (pyrB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1379Rv1381, (MTCY02B12.15), pyrC, len: 430. Probable dihydroorotase, similar e.g. to SW:PYRC_BACCL P46538 (40.5%identity in 395 aa overlap); contains PS00483 Dihydroorotasesignature 2 (pyrC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1380Rv1382hypothetical protein Rv1382 {Mycobacterium tuberculosis H37Rv (lab strain)}
1381Rv1383, (MTCY02B12.17), carA, len: 376. Carbamoyl-phosphate synthase, similar to e.g. CARA_ECOLI P00907 carbamoyl-phosphate synthase small chain (382 aa), fasta scores,opt: 796, E(): 0, (45.5% identity in 382 aa overlap); contains PS00442 Glutamine amidotransfe (carA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1382Rv1385, (MTCY21B4.02), pyrF, len: 274. orotidine 5-phosphate decarboxylase, identical to M. bovis, DCOP_MYCBOP42610 (274 aa); contains PS00156 Orotidine 5-phosphate decarboxylase active site (pyrF) {Mycobacterium tuberculosis H37Rv (lab strain)}
1383Rv1386, (MTCY21B4.03), len: 102. Member of M. tuberculosis PE family, similar to many e.g. G913039 ORF 3 OF PGRS TANDEM REPEAT {polymorphic GC-rich sequence)(100 aa), fasta scores, opt: 149, E(): 0.0013, (31.5% identity in 92 aa overlap), also G699138 U1756A (9 (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1384Rv1387, (MTCY21B4.04), len: 539, Member of M. tuberculosis PPE family of protein, similar to many e.g. Y05F_MYCTU Q10892 hypothetical 46.9 kd protein cy251.15 (463 aa), fasta scores; E(): 4.2e-26, 37.7% identity in 531 aa overlap; contains PS00343 Gram-positive (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1385Rv1388, (MTCY21B4.05), len: 190. Almost identical to, but longer than M. smegmatis TR:P96802 (EMBL:U75344) integration host factor (mIHF) for mycobacteriophage L5 (105 aa), fasta scores; E(): 0, 96.1% identity in 102 aa overlap (mIHF) {Mycobacterium tuberculosis H37Rv (lab strain)}
1386Rv1389, (MTCY21B4.06), gmk, len: 208, Probable guanylate kinase, similar to e.g. KGUA_ECOLI P24234 guanylate kinase (207 aa) fasta scores, opt: 424, E(): 6.6e-20, (35.9%identity in 184 aa overlap); contains PS00017 ATP/GTP-binding site motif A (P-loop), PS00856 (gmk) {Mycobacterium tuberculosis H37Rv (lab strain)}
1387Rv1390hypothetical protein Rv1390 {Mycobacterium tuberculosis H37Rv (lab strain)}
1388Rv1391, (MTCY21B4.08), dfp, len: 418. Flavoprotein(dfp), similar to e.g. DFP_ECOLI P24285 protein dfp, E. coli (430 aa), fasta scores, opt: 763, E(): 0, (40.2% identityin 408 aa overlap) (dfp) {Mycobacterium tuberculosis H37Rv (lab strain)}
1389Rv1392, (MTCY21B4.09), metK, len: 403. S-adenosylmethionine synthetase,similar to e.g. METK_STAAU P50307 (397aa), fasta scores, opt: 1484, E(): 0, (58.0% identity in 400aa overlap); contains PS00376 S-adenosylmethionine synthetase signature 1, PS00377 S-adenosy (metK) {Mycobacterium tuberculosis H37Rv (lab strain)}
1390Rv1393chypothetical protein Rv1393c {Mycobacterium tuberculosis H37Rv (lab strain)}
1391Rv1394chypothetical protein Rv1394c {Mycobacterium tuberculosis H37Rv (lab strain)}
1392Rv1396c, (MTCY21B4.13c), len: 576. Member of the PEfamily, PGRS subfamily of M. tuberculosis proteins, strongsimilarity to many e.g. glycine rich protein eg MTCY130.10C,E245019 hypothetical 49.6 kDa protein (603 aa), fasta scores, opt: 1945, E(): 0, (57.5% ident (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1393Rv1397chypothetical protein Rv1397c {Mycobacterium tuberculosis H37Rv (lab strain)}
1394Rv1398chypothetical protein Rv1398c {Mycobacterium tuberculosis H37Rv (lab strain)}
1395Rv1399c, (MTCY21B4.16c), len: 319. Possible lipase most similar to G695278 lipase like enzyme (364 aa), fasta scores, opt: 648, E(): 4.4e-34, (37.3% identity in 327 aaoverlap), similar to MTCY21B4.17c (58.1% identical in 315 aa overlap) (lipH) {Mycobacterium tuberculosis H37Rv (lab strain)}
1396Rv1400c, (MTCY21B4.17c), len: 320. Possible lipase,most similar to G695278 lipase like enzyme (364 aa) opt: 611, E(): 3.5e-30, (36.6% identity in 352 aa overlap), similar to MTCY21B4.16c (58.1% identical in 315 aa overlap) (lipI) {Mycobacterium tuberculosis H37Rv (lab strain)}
1397Rv1401hypothetical protein Rv1401 {Mycobacterium tuberculosis H37Rv (lab strain)}
1398Rv1402, (MTCY21B4.19), len: 655. Similar to e.g. PRIA_ECOLI P17888 primosomal protein n (replication factor Y) (732 aa), fasta scores, opt: 386, E(): 1.3e-16, (27.6% identity in 711 aa overlap) (priA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1399Rv1403chypothetical protein Rv1403c {Mycobacterium tuberculosis H37Rv (lab strain)}
1400Rv1404hypothetical protein Rv1404 {Mycobacterium tuberculosis H37Rv (lab strain)}
1401Rv1405chypothetical protein Rv1405c {Mycobacterium tuberculosis H37Rv (lab strain)}
1402Rv1406, (MTCY21B4.23), fmt, len: 312.fmt, Probablemethionyl-trna formyltransferase similar to many, e.g. FMT_ECOLI P23882 methionyl-trna formyltransferase (314 aa), fasta scores, opt: 616, E(): 6.7e-31, (39.3% identity in 303 aa overlap) (fmt) {Mycobacterium tuberculosis H37Rv (lab strain)}
1403Rv1407, (MTCY21B4.24), len: 457. fmu, similar to e.g. SUN_ECOLI P36929 sun protein (fmu protein). escherichia coli (429 aa), fasta scores; E(): 2.5e-20, 30.6% identity in 451 aa overlap (fmu) {Mycobacterium tuberculosis H37Rv (lab strain)}
1404Rv1408, (MTCY21B4.25), rpe, len: 232. Probable ribulose-phosphate 3-epimerase, similar to many, e.g. CXEC_ALCEU P40117, (241 aa), fasta scores, opt: 638, E(): 1.5e-34, (48.3% identity in 234 aa overlap) and RPE_ECOLI P32661 ribulose-phosphate 3-epimerase (225 a (rpe) {Mycobacterium tuberculosis H37Rv (lab strain)}
1405Rv1409, (MTCY21B4.26), ribD, len: 339. Probable riboflavin-specific deaminase, similar to many, e.g. RIBD_ECOLI P25539 riboflavin-specific deaminase (367 aa), fasta scores; E(): 0, 39.8% identity in 364 aa overlap; contains PS00903 Cytidine and deoxycytidylate (ribG) {Mycobacterium tuberculosis H37Rv (lab strain)}
1406Rv1410chypothetical protein Rv1410c {Mycobacterium tuberculosis H37Rv (lab strain)}
1407Rv1411c, (MTCY21B4.28c), len: 236. Probable lipoprotein, similar to MTCY50.12 (35.1% identity in 245 aa overlap). Contains N-terminal signal sequence and appropriately positioned prokaryotic lipoprotein lipid attachment site (PS00013) (lprG) {Mycobacterium tuberculosis H37Rv (lab strain)}
1408Rv1412, (MTCY21B4.29), ribC, len: 201. Riboflavin synthase alpha chain, strong similarity to eg RISA_ACTPL P50854 (215 aa), fasta scores, opt: 586, E(): 1.8e-33, (50.8%identity in 197 aa overlap); contains 2 x PS00693 Riboflavinsynthase alphachain family signat (ribC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1409Rv1413hypothetical protein Rv1413 {Mycobacterium tuberculosis H37Rv (lab strain)}
1410Rv1414hypothetical protein Rv1414 {Mycobacterium tuberculosis H37Rv (lab strain)}
1411Rv1415, (MTCY21B4.33), ribA, len: 428. Probable gtpcyclohydrolase ii, similar to e.g. GCH2_BACSU P17620 (398aa), fasta scores, opt: 1388, E(): 0, (55.4% identity in 399aa overlap) (ribA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1412Rv1416, (MTCY21B4.34), ribH, len: 154. Probable riboflavin synthase beta chain,similar to eg RISB_ECOLI P25540(156 aa), fasta scores, opt: 330, E(): 1.8e-15, (44.1% identity in 145 aa overlap); Note alternative GTG start possible overlapping stop codon of MTCY2 (ribH) {Mycobacterium tuberculosis H37Rv (lab strain)}
1413Rv1417hypothetical protein Rv1417 {Mycobacterium tuberculosis H37Rv (lab strain)}
1414Rv1418, (MTCY21B4.36), len: 228. Unknown. Probable lipoprotein. Contains N-terminal signal sequence and appropriately positioned prokaryotic lipoprotein lipid attachmentsite (PS00013) (lprH) {Mycobacterium tuberculosis H37Rv (lab strain)}
1415Rv1419hypothetical protein Rv1419 {Mycobacterium tuberculosis H37Rv (lab strain)}
1416Rv1420, (MTCY21B4.38), uvrC, len: 646. Probable excinuclease abc subunit c, similar to many e.g. UVRC_PSEFL P32966 excinuclease abc subunit c (607 aa), fasta scores, opt: 738, E(): 8.4e-39, (36.6% identity in 629 aa overlap) (uvrC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1417Rv1421hypothetical protein Rv1421 {Mycobacterium tuberculosis H37Rv (lab strain)}
1418Rv1422hypothetical protein Rv1422 {Mycobacterium tuberculosis H37Rv (lab strain)}
1419Rv1423hypothetical protein Rv1423 {Mycobacterium tuberculosis H37Rv (lab strain)}
1420Rv1424chypothetical protein Rv1424c {Mycobacterium tuberculosis H37Rv (lab strain)}
1421Rv1425hypothetical protein Rv1425 {Mycobacterium tuberculosis H37Rv (lab strain)}
1422Rv1426c, (MTCY493.28), len: 420. Unknown, possibleesterase, similar to MTCY493.28, MTCY08D5.15, MTCY21B4.16chighly similar esp. in C-terminus to M. tuberculosis hypothetical protein Q50681 (431 aa) (50.1% identity in 411 aa overlap), and also similar in central (lipO) {Mycobacterium tuberculosis H37Rv (lab strain)}
1423Rv1427c, (MTCY493.27), len: 535. fadD12, Possible long chain long-chain-fatty-acid-CoA ligase similar to eg. PC60_YEAST P38137 peroxisomal-coenzyme a synthetase (543 aa), fastascores; opt: 507 z-score: 579.4 E(): 2.9e-25, 30.4%identity in 365 aa overlap Contains (fadD12) {Mycobacterium tuberculosis H37Rv (lab strain)}
1424Rv1428chypothetical protein Rv1428c {Mycobacterium tuberculosis H37Rv (lab strain)}
1425Rv1429hypothetical protein Rv1429 {Mycobacterium tuberculosis H37Rv (lab strain)}
1426Rv1430, (MTCY493.24c), len: 528. N-terminus is highly similar to the conserved N-terminus of the M. tuberculosis PE family of proteins, eg. Y0D4_MYCTU Q50594 (55.9% identity in 127 aa overlap), although the glycine-rich C-terminal region is not present. The C-t (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1427Rv1431hypothetical protein Rv1431 {Mycobacterium tuberculosis H37Rv (lab strain)}
1428Rv1432hypothetical protein Rv1432 {Mycobacterium tuberculosis H37Rv (lab strain)}
1429Rv1433hypothetical protein Rv1433 {Mycobacterium tuberculosis H37Rv (lab strain)}
1430Rv1434hypothetical protein Rv1434 {Mycobacterium tuberculosis H37Rv (lab strain)}
1431Rv1435chypothetical protein Rv1435c {Mycobacterium tuberculosis H37Rv (lab strain)}
1432Rv1436, (MTCY493.18c), gap, len: 339. Glyceraldehyde 3-phosphate dehydrogenase (EC 1.2.1.12),highly similar toeg. G3P_MYCLE P46713 glyceraldehyde 3-phosphate dehydrogenase (339 aa), fasta scores; opt: 1933 z-score: 2154.9 E():0,89.1% identity in 339 aa overlap. (gap) {Mycobacterium tuberculosis H37Rv (lab strain)}
1433Rv1437, (MTCY493.17c), pgk, len: 412. Phosphoglycerate kinase, highly similar to eg.PGK_MYCLE P46712 phosphoglyceratekinase (ec 2.7.2.3) (416 aa), fasta scores; opt: 2153 z-score: 2423.8 E(): 0, 80.4% identity in 414 aa overlap.Contains PS00111 Phosphoglycerate (pgk) {Mycobacterium tuberculosis H37Rv (lab strain)}
1434Rv1438, (MTCY493.16c), tpi, len: 261. Triosephosphate isomerase, highly similar to eg. TPIS_MYCLE P46711 triosephosphate isomerase (ec 5.3.1.1) (261 aa), fasta scores; opt: 1456z-score: 1729.0 E(): 0, 83.9% identity in 261 aa overlapContains PS00171 Triosephosp (tpi) {Mycobacterium tuberculosis H37Rv (lab strain)}
1435Rv1439chypothetical protein Rv1439c {Mycobacterium tuberculosis H37Rv (lab strain)}
1436Rv1440, (MTCY493.14c), len: 117. Unknown, possiblemembrane protein, slight similarity to SECG_ECOLI P33582 protein-export membrane protein secg (110 aa), fasta scores;opt: 117 z-score: 157.9 E(): 0.089, 27.5% identity in 69 aaoverlap (secG) {Mycobacterium tuberculosis H37Rv (lab strain)}
1437Rv1441c, (MTCY493.13), len: 491. member of the PGRS(PE) family of glycine-rich proteins, similar to eg. Y0DP_MYCTU Q50615 hypothetical glycine-rich 40.8 kd protein (498aa), fasta scores; opt: 1625 z-score: 1118.3 E(): 0, 55.2%identity in 518 aa overlap (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1438Rv1442, (MTCY493.12c), bisC, len: 766. Biotin sulfoxide reductase, similar to eg. BISC_ECOLI P20099 biotin sulfoxide reductase (739 aa), fasta scores; opt: 1271 z-score:1436.6E():0, 40.2% identity in 744 aa overlap (bisC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1439Rv1443chypothetical protein Rv1443c {Mycobacterium tuberculosis H37Rv (lab strain)}
1440Rv1444chypothetical protein Rv1444c {Mycobacterium tuberculosis H37Rv (lab strain)}
1441Rv1445c, (MTCY493.09), devB, len: 247. Possible glucose-6-phosphate 1-dehydrogenase belongs to a different family to the upstream gene zwf2; similar to eg.DEVB_ANASP P46016 putativeglucose-6-phosphate 1-dehydrogenase (239 aa), fasta scores;opt: 439 z-score: 490. (devB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1442Rv1446c, (MTCY493.08), opcA, len: 303. Highly similar toS72774 B1496_F1_30 protein - Mycobacterium leprae (265aa)opt:1056 z-score: 1250.8 E(): 0; (70.3% identity in 239aa overlap). Also similar to eg. OPCA_NOSS2 P48971 putative oxppcycle protein opca. nost (465 (opcA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1443Rv1447c, (MTCY493.07), zwf2, len: 514. Glucose-6-phosphate 1-dehydrogenase, highly similar to eg.G6PD_SYNY3 P73411 glucose-6-phosphate 1-dehydrogenase (EC 1.1.1.49) (509aa), fastascores; opt: 1578 z-score: 1827.3 E(): 0, 46.8%identity in509 aa overlap. Contains (zwf2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1444Rv1448c, (MTCY493.06), tal, len: 373. Transaldolasehighly similar to eg.TAL_MYCLE P55193 transaldolase (ec 2.2.1.2) fromMycobacterium leprae (375 aa), fasta scores; opt: 1891z-score: 2186.1 E(): 0, 78.6% identity in 370 aa overlap (tal) {Mycobacterium tuberculosis H37Rv (lab strain)}
1445Rv1449c, (MTCY493.05), tkt, len: 700. Transketolasestart site chosen by homology; highly similar to eg. TKT_MYCLE P46708 transketolase (ec 2.2.1.1) (tk) from Mycobacterium leprae(699 aa), fasta scores; opt: 4216 z-score: 4718.5E(): 0, 89.1% identity in 700 aa ov (tkt) {Mycobacterium tuberculosis H37Rv (lab strain)}
1446Rv1450c, (MTCY493.04), len: 1329. member of the PGRS (PE) family of glycine-rich proteins, similar to eg. Y03A_MYCTU Q10637hypothetical glycine-rich 49.6 kd protein (603aa), fasta scores; opt: 2112 z-score: 1390.9 E(): 0, 56.5%identity in630 aa overlap. (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1447Rv1451, (MTCY493.03c),ctaB , len: 308 aa, Probablecytochrome C oxidase assembly factor, probable intgral membrane protein, highly similar to M. leprae Q49685 CYOE (300aa), fasta scores; opt: 1636 z-score: 1988.8 E(): 0 82.7% identity in 307 aa overlap (ctaB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1448Rv1452c, (MTCY493.02), len: 741. Member of the PGRS(PE) family of glycine-rich proteins, similar to eg. Y03A_MYCTU Q10637 hypothetical glycine-rich 49.6 kd protein (603aa), fasta scores; opt: 2090 z-score: 1407.8 E(): 0, 56.3%identity in 641aa overlap (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1449Rv1453hypothetical protein Rv1453 {Mycobacterium tuberculosis H37Rv (lab strain)}
1450Rv1454c, (MTV007.01c), qor, len: 328. Probable quinone oxidoreductase (EC 1.6.5.5) (NADPH:QUINONE REDUCTASE).FASTA scores: U87282|RCU87282_2 Rhodobacter capsulatus cbbIIoper (323aa) opt: 849 E(): 0; (44.7% identity in 329 aaoverlap). Contains PS01162 Quinone oxi (qor) {Mycobacterium tuberculosis H37Rv (lab strain)}
1451Rv1455hypothetical protein Rv1455 {Mycobacterium tuberculosis H37Rv (lab strain)}
1452Rv1456chypothetical protein Rv1456c {Mycobacterium tuberculosis H37Rv (lab strain)}
1453Rv1457chypothetical protein Rv1457c {Mycobacterium tuberculosis H37Rv (lab strain)}
1454Rv1458chypothetical protein Rv1458c {Mycobacterium tuberculosis H37Rv (lab strain)}
1455Rv1459chypothetical protein Rv1459c {Mycobacterium tuberculosis H37Rv (lab strain)}
1456Rv1460hypothetical protein Rv1460 {Mycobacterium tuberculosis H37Rv (lab strain)}
1457Rv1461hypothetical protein Rv1461 {Mycobacterium tuberculosis H37Rv (lab strain)}
1458Rv1462hypothetical protein Rv1462 {Mycobacterium tuberculosis H37Rv (lab strain)}
1459Rv1463hypothetical protein Rv1463 {Mycobacterium tuberculosis H37Rv (lab strain)}
1460Rv1464hypothetical protein Rv1464 {Mycobacterium tuberculosis H37Rv (lab strain)}
1461Rv1465hypothetical protein Rv1465 {Mycobacterium tuberculosis H37Rv (lab strain)}
1462Rv1466hypothetical protein Rv1466 {Mycobacterium tuberculosis H37Rv (lab strain)}
1463Rv1467c, (MTV007.14c), len: 609.fadE15, Possible acyl-coAdehydrogenase, weakly similar to many e.g. ACDS_MEGEL Q06319 acyl-coa dehydrogenase, short-chain specific (383 aa), fasta scores; E(): 2e-12, 25.4% identity in 410 aa overlap. TBparse score is 0.892 (fadE15) {Mycobacterium tuberculosis H37Rv (lab strain)}
1464Rv1468c, (MTV007.15c), len: 370. Member of Gly-richPE family, subfamily PGRS. TBparse score is 0.856 (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1465Rv1469, (MTV007.16), len: 657. ctpD, Probable cation-transporting ATPase. FASTA scores: gp|D64005|SYCSLRG_46 Synechocystis sp.PCC6803 (642 aa) opt: 1438 z-score: 1459.9E(): 0; 41.9% identity in 592 aa overlap. Contains PS00154E1-E2ATPases phosphorylation site. (ctpD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1466Rv1470, (MTV007.17), trxA, len: 124. Thioredoxin. FASTA scores: sp|P12243|THI1_ANANI THIOREDOXIN 1 (TRX-1) (THIOREDOXI (106 aa) opt: 201 z-score: 271.6 E(): 9.2e-08; 35.4% identity in 99 aa overlap. Highly similar to trxB, FASTA scores:opt: 402 z-score: 745.6 E (trxA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1467Rv1471, (MTV007.18), trxB, len: 123. Thioredoxin. Similar to many bacterial thioredoxins e.g. P00275. FASTA scores: owl|AE000344|ECAE0003448 ECAE000344 NID: g1788927 - Es (139 aa)opt: 290 z-score: 370.0 E(): 1.8e-13; 44.3% identity in 97aa overlap. Contains PS0 (trxB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1468Rv1472, (MTV007.19), len: 285. echA12, Probable enoyl-CoA hydratase, similar to many especially the M. leprae enzyme P53526. FASTA scores: P53526|ECHH_MYCLE PUTATIVE ENOYL-COA HYDRATASE (EC (294 aa) opt: 1265 z-score: 1494.1 E(): 0; 72.0% identity in 271 aa ove (echA12) {Mycobacterium tuberculosis H37Rv (lab strain)}
1469Rv1473hypothetical protein Rv1473 {Mycobacterium tuberculosis H37Rv (lab strain)}
1470Rv1474chypothetical protein Rv1474c {Mycobacterium tuberculosis H37Rv (lab strain)}
1471Rv1475c, (MTV007.22c), acn, len: 943. Probable aconitate hydratase, similar to many (e.g. P70920), closest toM. avium enzyme. FASTA scores: gp|AF0021|AF002133_2 Mycobacterium avium strain GIR10 (961 aa) opt: 5072 z-score: 5479.6 E(): 0; (82.8% identity in 943 aa (acn) {Mycobacterium tuberculosis H37Rv (lab strain)}
1472Rv1476hypothetical protein Rv1476 {Mycobacterium tuberculosis H37Rv (lab strain)}
1473Rv1477hypothetical protein Rv1477 {Mycobacterium tuberculosis H37Rv (lab strain)}
1474Rv1478hypothetical protein Rv1478 {Mycobacterium tuberculosis H37Rv (lab strain)}
1475Rv1479, (MTV007.26), moxR, len: 377. Probable regulatory protein similar to regulator of formation of active methanol dehyrogenase in B.burgdorferi (329 aa) and P.denitrificans. Highly similar to MoxR homologs of M. tuberculosis and M. avium but these both diff (moxR) {Mycobacterium tuberculosis H37Rv (lab strain)}
1476Rv1480hypothetical protein Rv1480 {Mycobacterium tuberculosis H37Rv (lab strain)}
1477Rv1481hypothetical protein Rv1481 {Mycobacterium tuberculosis H37Rv (lab strain)}
1478Rv1482chypothetical protein Rv1482c {Mycobacterium tuberculosis H37Rv (lab strain)}
1479Rv1483, (MTCY277.04), fabG1, len: 247. fabG1, Probable 3-oxoacyl-[acyl-carrier protein] reductase, identical to M. bovis G1155269 putative ketoacyl acp reductase (247 aa), strong similarity to FABG_ECOLI P25716 3-oxoacyl-[acyl-carrier protein] reductase (244 aa (fabG1) {Mycobacterium tuberculosis H37Rv (lab strain)}
1480Rv1484, (MTCY277.05), inhA, len: 269. Identical toINHA_MYCTU P46533 enoyl-[acyl-carrier-protein] reductase andto M. bovis G1155270 enoyl acp reductase (inhA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1481Rv1485, (MTCY277.06), hemZ, len: 344. Ferrochelatase similar to e.g. HEMZ_BACSU P32396 ferrochelatase (310 aa), FASTA scores, opt:490, E(): 2e-24, (30.2% identity in 295 aa overlap) (hemZ) {Mycobacterium tuberculosis H37Rv (lab strain)}
1482Rv1486chypothetical protein Rv1486c {Mycobacterium tuberculosis H37Rv (lab strain)}
1483Rv1487hypothetical protein Rv1487 {Mycobacterium tuberculosis H37Rv (lab strain)}
1484Rv1488hypothetical protein Rv1488 {Mycobacterium tuberculosis H37Rv (lab strain)}
1485Rv1489chypothetical protein Rv1489c {Mycobacterium tuberculosis H37Rv (lab strain)}
1486Rv1490hypothetical protein Rv1490 {Mycobacterium tuberculosis H37Rv (lab strain)}
1487Rv1491chypothetical protein Rv1491c {Mycobacterium tuberculosis H37Rv (lab strain)}
1488Rv1492, (MTCY277.14), mutA, len: 615. Methylmalonyl-coa mutase beta-subunit, strong similarity to e.g. MUTA_STRCM Q05064 methylmalonyl-coa mutase beta-subunit (616 aa) fasta scores, opt: 1512, E(): 0, (45.9% identity in 628 aaoverlap); contains PS00213 Lipocali (mutA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1489Rv1493, (MTCY277.15), mutB, len: 750. Methylmalonyl-coa mutase alpha-subunit, strong similarity to e.g. MUTB_STRCM Q05065 methylmalonyl-coa mutase alpha-subunit (733 aa)fasta scores, opt: 3562, E(): 0, (75.8% identity in 730 aaoverlap); contains PS00544 Methylm (mutB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1490Rv1494hypothetical protein Rv1494 {Mycobacterium tuberculosis H37Rv (lab strain)}
1491Rv1495hypothetical protein Rv1495 {Mycobacterium tuberculosis H37Rv (lab strain)}
1492Rv1496hypothetical protein Rv1496 {Mycobacterium tuberculosis H37Rv (lab strain)}
1493Rv1497, (MTCY277.19), len: 429. Probable esterase,very similar to MTCY09F9.41c putative esterase and to G151214 esterase (389 aa), FASTA scores, opt: 604, E(): 1e-31,(34.4%identity in 389 aa overlap) (lipL) {Mycobacterium tuberculosis H37Rv (lab strain)}
1494Rv1498chypothetical protein Rv1498c {Mycobacterium tuberculosis H37Rv (lab strain)}
1495Rv1499hypothetical protein Rv1499 {Mycobacterium tuberculosis H37Rv (lab strain)}
1496Rv1500hypothetical protein Rv1500 {Mycobacterium tuberculosis H37Rv (lab strain)}
1497Rv1501hypothetical protein Rv1501 {Mycobacterium tuberculosis H37Rv (lab strain)}
1498Rv1502hypothetical protein Rv1502 {Mycobacterium tuberculosis H37Rv (lab strain)}
1499Rv1503chypothetical protein Rv1503c {Mycobacterium tuberculosis H37Rv (lab strain)}
1500Rv1504chypothetical protein Rv1504c {Mycobacterium tuberculosis H37Rv (lab strain)}
1501Rv1505chypothetical protein Rv1505c {Mycobacterium tuberculosis H37Rv (lab strain)}
1502Rv1506chypothetical protein Rv1506c {Mycobacterium tuberculosis H37Rv (lab strain)}
1503Rv1507chypothetical protein Rv1507c {Mycobacterium tuberculosis H37Rv (lab strain)}
1504Rv1508chypothetical protein Rv1508c {Mycobacterium tuberculosis H37Rv (lab strain)}
1505Rv1509hypothetical protein Rv1509 {Mycobacterium tuberculosis H37Rv (lab strain)}
1506Rv1510hypothetical protein Rv1510 {Mycobacterium tuberculosis H37Rv (lab strain)}
1507Rv1511, (MTCY277.33), gmdA, len: 340. Probable GDP-D-mannose dehydratase, similar to e.g. PSEUDOMONAS AERUGINOSA G755218 GDP-D-MANNOSE DEHYDRATASE (GCA) (323 aa), fastascores, opt: 1073, z-score: 1269.9 E(): 0, (51.9% identityin320 aa overlap) and to S74433 GDP (gmdA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1508Rv1512, (MTCY277.34), len: 322. epiA, PROBABLE NUCLEOTIDE SUGAR EPIMERASE , similar to WCAG_ECOLI P32055 colanic acid biosynthesis protein wcaG (321 aa), fasta scores;opt: 835 z-score: 1489.0 E(): 0, 53.5% identity in 316 aa overlap (epiA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1509Rv1513hypothetical protein Rv1513 {Mycobacterium tuberculosis H37Rv (lab strain)}
1510Rv1514chypothetical protein Rv1514c {Mycobacterium tuberculosis H37Rv (lab strain)}
1511Rv1515chypothetical protein Rv1515c {Mycobacterium tuberculosis H37Rv (lab strain)}
1512Rv1516chypothetical protein Rv1516c {Mycobacterium tuberculosis H37Rv (lab strain)}
1513Rv1517hypothetical protein Rv1517 {Mycobacterium tuberculosis H37Rv (lab strain)}
1514Rv1518hypothetical protein Rv1518 {Mycobacterium tuberculosis H37Rv (lab strain)}
1515Rv1519hypothetical protein Rv1519 {Mycobacterium tuberculosis H37Rv (lab strain)}
1516Rv1520hypothetical protein Rv1520 {Mycobacterium tuberculosis H37Rv (lab strain)}
1517Rv1521, (MTCY19G5.07), len: 583.fadD25, Probable acyl-coAsynthase, simliar to many e.g. TR:P71495 (EMBL:U75685) ACYL-COA SYNTHASE from M. bovis (582 aa), fatsa scores; opt: 2486 z-score: 2167.3 E(): 0, 63.4% identity in 584 aa overlap. (fadD25) {Mycobacterium tuberculosis H37Rv (lab strain)}
1518Rv1522c, (MTCY19G5.06), len: 1146. Strong similarity to many mycobacterial membrane proteins e.g. M. leprae TR:Q49619 G466786 B1170_C1_181, putative transport protein (1008 aa) FASTA scores, opt: 2418, z-score: 2571.2, E(): 0, (51.0% identity in 1006 aa overlap) (mmpL12) {Mycobacterium tuberculosis H37Rv (lab strain)}
1519Rv1523hypothetical protein Rv1523 {Mycobacterium tuberculosis H37Rv (lab strain)}
1520Rv1524hypothetical protein Rv1524 {Mycobacterium tuberculosis H37Rv (lab strain)}
1521Rv1525, (MTCY19G5.03c), len: 261. Unknown. (wbbl2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1522Rv1526chypothetical protein Rv1526c {Mycobacterium tuberculosis H37Rv (lab strain)}
1523Rv1527c, (MTV045.01c-MTCY19G5.01), len: 2108.pks5, probable polyketide synthase, highly similar to many, e.g. MCAS_MYCBO Q02251 mycocerosic acid synthase from Mycobacterium bovis (2110 aa), fasta scores; opt: 6270 z-score: 7088.8 E(): 0, 63.6% identity in 2126 a (pks5) {Mycobacterium tuberculosis H37Rv (lab strain)}
1524Rv1528c, (MTV045.02), len: 165. Unknown, but shows some similarity to C-terminal part of hypothetical proteinsfrom M. tuberculosis and M. leprae, eg. gp|Z97188|MTCY409_10 M. tuberculosis cosmid (468), 37.9% identity in 66 aa overlap; or U00010_11 M. leprae cosmi (papA4) {Mycobacterium tuberculosis H37Rv (lab strain)}
1525Rv1529, (MTV045.03), len: 584. fadD24, but highlysimilar to possible polyketide synthase MTCY409.04c (584 aa),63.2% identity in 584 aa overlap, or MBU75685_1 M. bovisacyl-CoA synt (582 aa), 65.6% identity in 582 aa overlap and many other mycobacterial hypotheti (fadD24) {Mycobacterium tuberculosis H37Rv (lab strain)}
1526Rv1530, (MTV045.04), len: 367.adh, Probable alcoholdehydrogenase, zinc-dependent, similar to many e.g. gp|AE0009|AE000958_23 Archaeoglobus fulgidus section 1 (402 aa)FASTAscores: opt: 423 z-score: 484.4 E(): 1.8e-19; 31.7% identity in 341aa overlap; Contains PS (adh) {Mycobacterium tuberculosis H37Rv (lab strain)}
1527Rv1531hypothetical protein Rv1531 {Mycobacterium tuberculosis H37Rv (lab strain)}
1528Rv1532chypothetical protein Rv1532c {Mycobacterium tuberculosis H37Rv (lab strain)}
1529Rv1533hypothetical protein Rv1533 {Mycobacterium tuberculosis H37Rv (lab strain)}
1530Rv1534hypothetical protein Rv1534 {Mycobacterium tuberculosis H37Rv (lab strain)}
1531Rv1535hypothetical protein Rv1535 {Mycobacterium tuberculosis H37Rv (lab strain)}
1532Rv1536, (MTCY48.29c-MTCCY07A7A.05), len: 1041.ileS,Isoleucyl-trna synthetase, similar to eg SYIC_YEAST P09436isoleucyl-trna synthetase (1072 aa) FASTA scores, opt: 1447 z-score: 1645.4E(): 0, (37.8% identity in 1072 aa overlap);contains PS00178 Aminoacyl-transf (ileS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1533Rv1537, (MTCY48.28c), len: 463. dinX, Similar to umuc, mucb, samb,and impb (uv protection and mutation) eg IMPB_SALTY P18642, impb protein. salmonella typhimurium. (424 aa) FATA scores,opt: 386, z-score: 431.5, E(): 1.7e-17,(27.5% identity in 415 aa overlap) (dinX) {Mycobacterium tuberculosis H37Rv (lab strain)}
1534Rv1538c, (MTCY48.27), ansA, len: 326. Probable l-aparaginase, most similar to ASPG_BACLI P30363 l-asparaginase(322 aa) FASTA scores,opt: 417, z-score: 454.8, E(): 8.8e-19, (30.9% identity in 314 aa overlap); contains PS00917 Asparaginase / glutaminase active sit (ansA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1535Rv1539, (MTCY48.26c), lspA, len: 202. Probable lipoprotein signal peptidase, similar to eg LSPA_PSEFL P17942,(170 aa) FASTA scores, opt: 299, z-score: 338.6, E(): 2.6e-12, (38.3% identity in 167 aa overlap) (lspA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1536Rv1540hypothetical protein Rv1540 {Mycobacterium tuberculosis H37Rv (lab strain)}
1537Rv1541c, (MTCY48.24), len: 197. Possible lipoprotein, contains appropriately positioned prokaryotic membrane lipoprotein lipid attachment site (PS0013) (lprI) {Mycobacterium tuberculosis H37Rv (lab strain)}
1538Rv1542c, (MTCY48.23), glbN, len: 136. Belongs to the protozoan/cyanobacterial globin family. Similar to myoglobins e.g. GLB_PARCA P15160 myoglobin (hemoglobin). paramecium (116aa) FASTA scores, opt: 284, z-score: 358.1, E(): 2.1e-13,(35.7% identity in 115 aa ove (glbN) {Mycobacterium tuberculosis H37Rv (lab strain)}
1539Rv1543hypothetical protein Rv1543 {Mycobacterium tuberculosis H37Rv (lab strain)}
1540Rv1544hypothetical protein Rv1544 {Mycobacterium tuberculosis H37Rv (lab strain)}
1541Rv1545hypothetical protein Rv1545 {Mycobacterium tuberculosis H37Rv (lab strain)}
1542Rv1546hypothetical protein Rv1546 {Mycobacterium tuberculosis H37Rv (lab strain)}
1543Rv1547, (MTCY48.18c), dnaE, len: 1184. Probable dnapolymerase III, alpha chain, similar to e.g. DP3A_ECOLI P10443 dna polymerase iii, alpha chain (1160 aa) FASTA scores,opt: 1789, z-score: 2007.3, E(): 0, (36.5% identity in 1193aa overlap) (dnaE1) {Mycobacterium tuberculosis H37Rv (lab strain)}
1544Rv1548c, (MTCY48.17), len: 678. Member of the PPE family, similar to e.g. YHS6_MYCTU P42611 hypothetical 50.6kd protein in hsp65 3 region, (517 aa) FASTA scores, opt:1142, z-score: 1009.6, E(): 0, (40.6% identity in 616 aa overlap) also similar to MTCY31.06c, (5 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1545Rv1549, (MTCY48.16c), len: 175. fadD11, Similar tothe N-terminus of many fatty-acid coA ligases e.g. 4CL2_SOLTU P31685 4-coumarate--coa ligase 2 (545 aa), fasta scores;opt: 168 z-score: 238.4 E(): 4.4e-06, 30.4% identity in 112aa overlap possible frameshift wit (fadD11) {Mycobacterium tuberculosis H37Rv (lab strain)}
1546Rv1550, (MTCY48.15c), len: 571. fadD11, Probable fatty-acid coA ligase, similar to many e.g. LCFH_HAEIN P44446putative long-chain-fatty-acid--coa ligase (607 aa), FASTAscores, opt: 762, z-score: 806.2, E(): 2.3e-38, (34.4% identity in 436 aa overlap); contains (fadD11) {Mycobacterium tuberculosis H37Rv (lab strain)}
1547Rv1551, (MTCY48.14c), len: 621. Possible transferase, similarity to e.g. PLSB_HAEIN P44857 glycerol-3-phosphate acyltransferase, (810aa), FASTA scores, opt: 434, z-score: 511.3, E(): 6.2e-22,(27.6% identity in 395 aa overlap) (plsB1) {Mycobacterium tuberculosis H37Rv (lab strain)}
1548Rv1552, (MTCY48.13c), frdA, len: 583. Fumarate reductase flavoprotein, similar to e.g. FRDA_ECOLI P00363 fumarate reductase flavoprotein subunit (601 aa) FASTA scores,opt: 2102 z-score: 2367.6 E(): 0, (54.7% identity in 585 aaoverlap); contains PS00504 Fumarate (frdA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1549Rv1553, (MTCY48.12c), frdB, len: 247. Fumarate reductase iron-sulfur protein, similar to e.g. FRDB_ECOLI P00364 fumarate reductase iron-sulfur protein (243 aa) FASTA scores, opt: 846, z-score: 983.0, E(): 0, (50.0% identity in242aa overlap); contains PS00198 4F (frdB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1550Rv1554, (MTCY48.11c), frdC, len 126. Fumarate reductase 15 kd hydrophobic protein, similar to eg FRDC_ECOLI P03805 fumarate reductase 15 kd hydrophobic protein (131 aa)FASTA scores, opt: 268, z-score: 299.6, E(): 3.9e-10, (31.1%identity in 122 aa overlap) (frdC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1551Rv1555, (MTCY48.10c), frdD, len: 125. Fumarate reductase 13 kd hydrophobic protein, similar to e.g. FRDD_ECOLIP03806 fumarate reductase 13 kd hydrophobic protein (119 aa), FASTA scores, opt: 212, z-score: 262.7, E(): 4.4e-08, (36.8% identity in 106 aa overlap) (frdD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1552Rv1556hypothetical protein Rv1556 {Mycobacterium tuberculosis H37Rv (lab strain)}
1553Rv1557, (MTCY48.08c), len: 397. Probable membrane protein, strong similarity to C-terminal part of members oflarge mycobacterial membrane protein family including: MTCY04D9.15c, MTCY08D5.01c, MTCY19G5.06, MTCY20G9.34, etc. FASTAscore: Q11171|YV34_MYCTU HYPOTHET (mmpL6) {Mycobacterium tuberculosis H37Rv (lab strain)}
1554Rv1558hypothetical protein Rv1558 {Mycobacterium tuberculosis H37Rv (lab strain)}
1555Rv1559, (MTCY48.06c), ilvA, len: 429.ilvA, Probable probable threonine dehydratase, biosynthetic, similar to e.g. THD1_CORGL Q04513 threonine dehydratase biosynthetic, (436 aa) FASTA scores, opt: 1694, z-score: 1888.0, E(): 0, (61.9% identity in 415 aa overlap) (ilvA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1556Rv1560hypothetical protein Rv1560 {Mycobacterium tuberculosis H37Rv (lab strain)}
1557Rv1561hypothetical protein Rv1561 {Mycobacterium tuberculosis H37Rv (lab strain)}
1558Rv1562c, (MTCY48.03), glgZ, len: 580. Probable maltooligosyltrehalose trehalohydrolase. Similar to e.g. TR:Q44316 (EMBL:D63343) TREZ MALTOOLIGOSYL TREHALOSE TREHALOHYDROLASE from ARTHROBACTER SP (598 aa), fasta scores; opt: 2071z-score: 2131.2 E(): 0, 52.2% iden (glgZ) {Mycobacterium tuberculosis H37Rv (lab strain)}
1559Rv1563c, (MTCY48.02),len: 765. glgY, Probable maltooligosyl trehalose synthase. Strong similarity to TR:Q44315(EMBL:63343) TREY MALTOOLIGOSYL TREHALOSE SYNTHASE from ARTHROBACTER SP (775 aa) opt: 1953 E(): 0; (46.0% identity in789 aa overlap). Some similarity to (glgY) {Mycobacterium tuberculosis H37Rv (lab strain)}
1560Rv1564c, (MTCY48.01),glgX , len: 721, Strong similarity to treX, glycogen debranching enzyme (glgX), FASTA score: D83245 NID: g1890053- Sulfolobus acidocaldarius (713 aa) opt: 2396, E(): 0; (48.4% identity in 709 aa overlap), similar to GLGX_HAEIN P45178 glycoge (glgX) {Mycobacterium tuberculosis H37Rv (lab strain)}
1561Rv1565chypothetical protein Rv1565c {Mycobacterium tuberculosis H37Rv (lab strain)}
1562Rv1566chypothetical protein Rv1566c {Mycobacterium tuberculosis H37Rv (lab strain)}
1563Rv1567chypothetical protein Rv1567c {Mycobacterium tuberculosis H37Rv (lab strain)}
1564Rv1568, (MTCY336.35c), bioA, len: 437. Function: probable adenosylmethionine-8-amino-7-oxononanoate aminotransferase (EC2.6.1.62) O06622. Contains aminotransferases class-III pyridoxal-phosphate attachment site (PS00600). FASTAresults, BIOA_MYCLE P4548 (436 aa) (bioA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1565Rv1569, (MTCY336.34c), bioF, len: 386. Function: probable 8-amino-7-oxononanoate synthase (EC 2.3.1.47) O06621. Contains aminotransferases class-II pyridoxal-phosphate attachment site (PS00599). FASTA results, BIOF_MYCLE P45487(385 aa) opt: 1971; E(): 0; 80.1% (bioF) {Mycobacterium tuberculosis H37Rv (lab strain)}
1566Rv1570, (MTCY336.33c), bioD, len: 226. Function: probable dethiobiotin synthetase (EC 6.3.3.3) Similar to many. FASTA results, BIOD_MYCLE P45486 (223 aa) opt: 1059; E():0; 74.8% identity in 222 aa overlap. TBparse cY336.seq] (bioD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1567Rv1571hypothetical protein Rv1571 {Mycobacterium tuberculosis H37Rv (lab strain)}
1568Rv1572chypothetical protein Rv1572c {Mycobacterium tuberculosis H37Rv (lab strain)}
1569Rv1573hypothetical protein Rv1573 {Mycobacterium tuberculosis H37Rv (lab strain)}
1570Rv1574hypothetical protein Rv1574 {Mycobacterium tuberculosis H37Rv (lab strain)}
1571Rv1575hypothetical protein Rv1575 {Mycobacterium tuberculosis H37Rv (lab strain)}
1572Rv1576chypothetical protein Rv1576c {Mycobacterium tuberculosis H37Rv (lab strain)}
1573Rv1577chypothetical protein Rv1577c {Mycobacterium tuberculosis H37Rv (lab strain)}
1574Rv1578chypothetical protein Rv1578c {Mycobacterium tuberculosis H37Rv (lab strain)}
1575Rv1579chypothetical protein Rv1579c {Mycobacterium tuberculosis H37Rv (lab strain)}
1576Rv1580chypothetical protein Rv1580c {Mycobacterium tuberculosis H37Rv (lab strain)}
1577Rv1581chypothetical protein Rv1581c {Mycobacterium tuberculosis H37Rv (lab strain)}
1578Rv1582chypothetical protein Rv1582c {Mycobacterium tuberculosis H37Rv (lab strain)}
1579Rv1583chypothetical protein Rv1583c {Mycobacterium tuberculosis H37Rv (lab strain)}
1580Rv1584chypothetical protein Rv1584c {Mycobacterium tuberculosis H37Rv (lab strain)}
1581Rv1585chypothetical protein Rv1585c {Mycobacterium tuberculosis H37Rv (lab strain)}
1582Rv1586chypothetical protein Rv1586c {Mycobacterium tuberculosis H37Rv (lab strain)}
1583Rv1587chypothetical protein Rv1587c {Mycobacterium tuberculosis H37Rv (lab strain)}
1584Rv1588chypothetical protein Rv1588c {Mycobacterium tuberculosis H37Rv (lab strain)}
1585Rv1589, (MTCY336.15c), bioB, len: 349. Function: biotin synthetase (EC 2.8.1.-) O06601. FASTA results, BIOB_MYCLE P46715(345 aa) opt: 1982; E(): 0; 86.5% identity in 349aa overlap. TBparse score is 0.875 (bioB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1586Rv1590hypothetical protein Rv1590 {Mycobacterium tuberculosis H37Rv (lab strain)}
1587Rv1591hypothetical protein Rv1591 {Mycobacterium tuberculosis H37Rv (lab strain)}
1588Rv1592chypothetical protein Rv1592c {Mycobacterium tuberculosis H37Rv (lab strain)}
1589Rv1593chypothetical protein Rv1593c {Mycobacterium tuberculosis H37Rv (lab strain)}
1590Rv1594, (MTCY336.10c), nadA, len: 349. Function: quinolinate synthetase. Similar to many, FASTA results, Q49622 NADA (368 aa) opt:1994 E(): 0; 84.4% identity in 352 aa overlap (nadA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1591Rv1595, (MTCY336.09c), nadB, len: 527. Function: nadB, probable L-aspartate oxidase (EC 1.4.3.16). FASTA results,Q49617 L-ASPARTATE OXIDASE (QUINOLINATE SYNTHETASE) (424aa) opt: 2152; E(): 0; 82.0% identity in 400 aa overlap. Alsoshows some similarity to MTCY48 (nadB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1592Rv1596, (MTCY336.08c), nadC, len: 285. Function: probable nicotinate-nucleotide pyrophosphatase (EC 2.4.2.19)O06594. FASTA results, ADC_MYCLE P46714 (284 aa) opt: 1418; E(): 0; 79.2% identity in 283 aa overlap. TBparse score is 0.902 (nadC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1593Rv1597hypothetical protein Rv1597 {Mycobacterium tuberculosis H37Rv (lab strain)}
1594Rv1598chypothetical protein Rv1598c {Mycobacterium tuberculosis H37Rv (lab strain)}
1595Rv1599, (MTCY336.05c), hisD, len: 438. Function: probable histidinol dehydrogenase (EC 1.1.1.23) O08396. Contains histidinol dehydrogenase signature (PS00611). FASTA results, HISX_MYCSM P28736 (445 aa) opt: 2356 E(): 0; 83.1% identity in 437 aa overlap (hisD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1596Rv1600, (MTCY336.04c), hisC, len: 380. Function: probable histidinol-phosphate aminotransferase (EC 2.6.1.9)O06591. Contains aminotransferases class-II pyridoxal-phosphate attachment site ( PS00599). FASTA results, HIS8_STRCOP16246 (369 aa) opt: 1353; E(): 0; 5 (hisC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1597Rv1601, (MTCY336.03c), hisB, len: 210. Function: probable imidazole glycerol-phosphate dehydratase (EC 4.2.1.19). FASTA results, HIS7_STRCO P16247 (197 aa) opt: 763; E(): 0; 57.4% identity in 202 aa overlap. TBparse score is 0.910 (hisB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1598Rv1602, (MTCY336.02c), hisH, len: 206. Function: probable amidotransferase (EC 2.4.2.-). Contains glutamine amidotransferases class-I active site (PS00442). FASTA results, HIS5_STRCO P16249 (ec 2.4.2.-) (222 aa) opt: 872 E():0;61.0% identity in 210 aa overlap. (hisH) {Mycobacterium tuberculosis H37Rv (lab strain)}
1599Rv1603, (MTV046.01-MTCY336.01c), hisA, len: 245. Probable PHOSPHORIBOSYLFORMIMINO-5-AMINOIMIDAZOLE CARBOXAMIDERIBOTIDE ISOMERASE (EC 5.3.1.16) similar to many e.g. HIS4_STRCO P16250 phosphoribosylformimino-5-aminoimidaz (240 aa), fasta scores; opt: 1081 z-score (hisA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1600Rv1604, (MTV046.02), impA, len: 270. Probable inositol monophosphatase, similar to e.g. gp|AF0059|AF005905_2 Mycobacterium smegmatis phosphori (276 aa), FASTA scores: opt: 1241 z-score: 1462.4 E(): 0; 70.5% identity in 261 aa overlap (impA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1601Rv1605, (MTV046.03), hisF, len: 267. Probable cyclase involved in histidine biosynthetic pathway, similar tomany e.g. gp|AF0304|AF030405_1 Corynebacterium glutamicum cyclas (257 aa) FASTA scores: opt: 1201 z-score: 1428.4 E(): 0; 71.9% identity in 256 aa overla (hisF) {Mycobacterium tuberculosis H37Rv (lab strain)}
1602Rv1606, (MTV046.04), hisI2, len: 115. Probable phosphoribosyl-amp 1,6 cyclohydrolase similar to several, e.g. gp|X82010|RSHISI_2 R.sphaeroides HISI gene. Phosphorib (119aa) FASTA scores: opt: 378 z-score: 516.7 E(): 2.8e-21; 52.3% identity in 109 aa overlap. TB (hisI2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1603Rv1607, (MTV046.05), chaA, len: 360. Probable ionictransporter, putative calcium/proton antiporter, similar tomany, e.g. sp|P31801|CHAA_ECOLI CALCIUM/PROTON ANTIPORTER. (366 aa), opt: 736 z-score: 894.7 E(): 0; 35.9% identityin351 aa overlap. TBparse score is 0 (chaA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1604Rv1608c, (MTV046.06), bcpB, len: 154. Probable bacterioferritin comigratory protein, similar to many, e.g. gp|AE0003|ECAE000335_4 E. coli K-12 MG1655 se (156 aa), FASTAscores: opt: 329 z-score: 433.7 E(): 1.2e-16; 38.2% identity in 152 aa overlap, or gp|Z97179|M (bcpB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1605Rv1609, (MTCY01B2.01-MTV046.07), trpE, len: 516. Function: anthranilate synthase component I (EC 4.1.3.27). FASTA best: TRPE_CLOTM P14953 anthranilate synthase componenti (ec (494 aa), E(): 0, 42.6% identity in 498 aa overlap.Some similarity to MTCY253.35, 6.3e (trpE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1606Rv1610hypothetical protein Rv1610 {Mycobacterium tuberculosis H37Rv (lab strain)}
1607Rv1611, (MTCY01B2.03), len: 272. Function: probableindole-3-glycerol phosphate synthase (EC 4.1.1.48). Contains indole-3-glycerol phosphate synthase signature (PS00614).FASTA best: SLR0546 SYNECHOCYSTIS SP Q55508 HYPOTHETICAL33.0 KD PROTEIN. (295 aa) opt: 26; E (trpC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1608Rv1612, (MTCY01B2.04), trpB, len: 410. Function: probable tryptophan synthase beta chain (EC 4.2.1.20). FASTAbest: TRPB_CAUCR P12290 tryptophan synthase beta chain (406 aa) opt: 1662; E(): 0; (60.6% identity in 404 aa overlap) (trpB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1609Rv1613, (MTCY01B2.05), trpA, len: 270. Function: probable tryptophan synthase alpha chain (EC 4.2.1.20). FASTAbest: TRPA_THETH P16608 tryptophan synthase alpha chain (271 aa) opt: 601; E(): 2.2e-30; (43.0% identity in 251 aa overlap) (trpA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1610Rv1614, (MTCY01B2.06), len: 468. Unknown, possiblelgt/umpA, similar to many prolipoprotein diacylglyceryl transferase (EC 2.4.99.-). FASTA best: LGT_STAAU P52282 prolipoprotein diacylglyceryl transfer (279 aa) opt: 289; E():3.6e-09; (31.5% identity in 257 aa ov (lgt) {Mycobacterium tuberculosis H37Rv (lab strain)}
1611Rv1615hypothetical protein Rv1615 {Mycobacterium tuberculosis H37Rv (lab strain)}
1612Rv1616hypothetical protein Rv1616 {Mycobacterium tuberculosis H37Rv (lab strain)}
1613Rv1617, (MTCY01B2.09), pykA, len: 472. Function: probable pyruvate kinase (EC 2.7.1.40). FASTA best: CORYNEBACTERIUM GLUTAMICUM Q46078 PYRUVATE KINASE. (475 aa) opt: 2221; E(): 0; (72.2% identity in 468 aa overlap) (pykA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1614Rv1618, (MTCY01B2.10), tesB, len: 300. Possible acyl-coa thioesterase ii, similar to acyl-CoA thioesterases. FASTA best: TESB_ECOLI P23911 acyl-coa thioesterase ii (EC 3.1.2.-) (285 aa) opt: 495; E(): 2.9e-27; (32.5% identity in 283 aa overlap), alternative sta (tesB1) {Mycobacterium tuberculosis H37Rv (lab strain)}
1615Rv1619hypothetical protein Rv1619 {Mycobacterium tuberculosis H37Rv (lab strain)}
1616Rv1620c, (MTCY01B2.12c), len: 576. Function:cydC, probable ABC transporter, possibly CydC, contains ABC transporters family signature (PS00211) and ATP/GTP-binding site motif A (P-loop,PS00017). FASTA best: CYDC_ECOLI P23886 transport atp-binding protein cydc. ( (cydC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1617Rv1621c, (MTCY01B2.13c), len: 527. cydD, Function: probable ABC transporter, similar to many, possibly CydD, contains an ATP/GTP-binding site motif A (P-loop, PS00017) and ABC transporters family signature (PS00211). FASTA best:Q11019 Y07D_MYCTU (579 aa) opt: 53 (cydD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1618Rv1622c, (MTCY01B2.14c), cydB, len: 346. Function:probable cytochrome D ubiquinol oxidase subunit. FASTA best:P11027 CYDB_ECOLI CYTOCHROME D UBIQUINOL OXIDASE subunitII(379 aa) opt: 519; E(): 0; 32.3% identity in 372 aa overlap (cydB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1619Rv1623c, (MTCY01B2.15c), appC, len: 485. Function:probable cytochrome D ubiquinol oxidase subunit. FASTA best:SW:P26459 APPC_ECOLI CYTOCHROME BD-II OXIDASE SUBUNIT (514aa) opt:870; E(): 0; (35.9% identity in 485 aa overlap) (appC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1620Rv1624chypothetical protein Rv1624c {Mycobacterium tuberculosis H37Rv (lab strain)}
1621Rv1625chypothetical protein Rv1625c {Mycobacterium tuberculosis H37Rv (lab strain)}
1622Rv1626hypothetical protein Rv1626 {Mycobacterium tuberculosis H37Rv (lab strain)}
1623Rv1627chypothetical protein Rv1627c {Mycobacterium tuberculosis H37Rv (lab strain)}
1624Rv1628chypothetical protein Rv1628c {Mycobacterium tuberculosis H37Rv (lab strain)}
1625Rv1629, (MTCY01B2.21), polA, len: 904. Function: DNA polymerase I (EC 2.7.7.7). Has DNA polymerase family A signature (PS00447) at C-terminal end. FASTA best DPO1_MYCTUQ07700 DNApolymerase I (904 aa). Some similarity to MTCY49.30, (393 aa) E(): 2.2e-18; (38.7% (polA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1626Rv1630, (MTCY01B2.22), rpsA, len: 481. Function: ribosomal protein S1, RpsA. FASTA best: RS1_MYCLE P46836 30sribosomal protein S1. Mycobacterium leprae (482 aa) opt: 2655; E(): 0; (87.2% identity in 483 aa overlap) (rpsA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1627Rv1631hypothetical protein Rv1631 {Mycobacterium tuberculosis H37Rv (lab strain)}
1628Rv1632chypothetical protein Rv1632c {Mycobacterium tuberculosis H37Rv (lab strain)}
1629Rv1633, (MTCY01B2.25), uvrB, len: 698. Function: Excinuclease abc subunit b, has ATP/GTP-binding site motif A(P-loop; PS00017) near N-terminus. FASTA best: UVRB_MICLU P10125 Micrococcus luteus (709 aa) opt: 3268; E(): 0; (71.3% identityin 704 aa overlap) (uvrB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1630Rv1634hypothetical protein Rv1634 {Mycobacterium tuberculosis H37Rv (lab strain)}
1631Rv1635chypothetical protein Rv1635c {Mycobacterium tuberculosis H37Rv (lab strain)}
1632Rv1636hypothetical protein Rv1636 {Mycobacterium tuberculosis H37Rv (lab strain)}
1633Rv1637chypothetical protein Rv1637c {Mycobacterium tuberculosis H37Rv (lab strain)}
1634Rv1638, (MTCY06H11.01,MTCY06H11.02c), uvrA, len: 972. Excinuclease abc subunit a, similar to many e.g. UVRA_ECOLI P07671 excinuclease abc subunit a (940 aa), fasta files, opt:2573, E(): 0, (56.2% identity in 951 aa overlap); contains 2x PS00017 ATP/GTP-binding (uvrA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1635Rv1639chypothetical protein Rv1639c {Mycobacterium tuberculosis H37Rv (lab strain)}
1636Rv1640c, (MTCY06H11.04c), len: 1172. Long open reading frame of which the last 600 or so bases are similar toe.g. SYK_CRILO P37879 lysyl-trna synthetase (ec 6.1.1.6) (597 aa), this may indicate a frame shift upstream of the homology. Fasta scores, opt: 985, E(): (lysX) {Mycobacterium tuberculosis H37Rv (lab strain)}
1637Rv1641, (MTCY06H11.05), infC, len: 201. Initiation factor if-3, similar to eg IF3_BACST P03000 initiation factor if-3 (171 aa), fasta scores, opt: 560, E(): 1.9e-27, (50.6% identity in 166 aa overlap). Note that an AUC initiation codon has been used; The Bacill (infC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1638Rv1642, (MTCY06H11.06), rpmI, len: 64. 50s ribosomal protein l35, similar to eg RL35_SYNY3 P48959, (67 aa), fasta scores, opt: 179, E(): 2.7e-08, (51.6% identity in 64aaoverlap) (rpmI) {Mycobacterium tuberculosis H37Rv (lab strain)}
1639Rv1643, (MTCY06H11.07), rplt, len: 129. 50s ribosomal protein l20, similar to eg RL20_ECOLI P02421, (117 aa),fasta scores, opt: 438, E(): 5.8e-24, (60.3% identity in 116aa overlap); contains PS00937 Ribosomal protein L20 signature (rplT) {Mycobacterium tuberculosis H37Rv (lab strain)}
1640Rv1644, (MTCY06H11.08), len: 260, Possible 23s rrnamethyltransferase similar e.g. to TSNR_STRLU P52393 (270 aa), fasta scores, opt:276, E(): 3.6e-11, (27.6% identity in261 aa overlap) (tsnR) {Mycobacterium tuberculosis H37Rv (lab strain)}
1641Rv1645chypothetical protein Rv1645c {Mycobacterium tuberculosis H37Rv (lab strain)}
1642Rv1646, (MTCY06H11.11), len: 310. Member of the M.tuberculosis PE family of proteins, similar to eg YW36_MYCTUQ10873 hypothetical 53.7 kd protein cy39.36c (558aa), fastascores, opt: 411, E(): 1.3e-15, (34.4% identityin 320 aa overlap) (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1643Rv1647hypothetical protein Rv1647 {Mycobacterium tuberculosis H37Rv (lab strain)}
1644Rv1648hypothetical protein Rv1648 {Mycobacterium tuberculosis H37Rv (lab strain)}
1645Rv1649, (MTCY06H11.14), pheS, len: 341. Phenylalanyl-trna synthetase alpha chain, SYFA_ECOLI P08312, (327 aa),fasta scores, opt: 978, E(): 0, (46.5% identity in 331 aa overlap), homology suggests this start site, but there is apotential rbs upstream of a gtg at (pheS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1646Rv1650, (MTCY06H11.15), pheT, len: 831. Phenylalanyl-trna synthetase beta chain, similar eg to SYFB_ECOLI P07395, (795 aa), fasta scores, opt: 995, E(): 0, (31.8% identityin 847 aa overlap) (pheT) {Mycobacterium tuberculosis H37Rv (lab strain)}
1647Rv1651c, (MTCY06H11.16c), len: 1011. member of the M. tuberculosis glycine-rich PGRS (PE) family, similar to eg Y03A_MYCTU Q10637 hypothetical glycine-rich 49.6 kd pro (603 aa), fasta scores, opt: 1757, E(): 0, (50.8% identity in 714aa overlap) (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1648Rv1652, (MTCY06H11.17), argC, len: 352. N-acetyl-gamma-glutamyl-phosphate reductase, similar to many e.g. ARGC_STRCL P54896 n-acetyl-gamma-glutamyl-phosphate red (340 aa), fasta scores, opt: 1119, E(): 0, (56.9% identity in350 aa overlap) (argC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1649Rv1653, (MTCY06H11.18), argJ, len: 404. Glutamate n-acetyltransferase, similar to eg ARGJ_BACSU P36843, (406 aa), fasta scores, opt: 727, E(): 0, (36.3% identity in 410 aa overlap) (argJ) {Mycobacterium tuberculosis H37Rv (lab strain)}
1650Rv1654, (MTCY06H11.19), argB, len: 294. Acetylglutamate kinase, similar to ARGB_CORGL Q59281, (294 aa), fasta scores,opt: 1209, E(): 0, (64.4% identity in 270 aa overlap) (argB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1651Rv1655, (MTCY06H11.20), argD, len: 400. Acetylornithine aminotransferase, similar to eg ARGD_ECOLI P18335 (406aa), fasta scores, opt: 958, E(): 0, (38.6% identity in 404aa overlap), contains PS00600 Aminotransferases class-IIIpyridoxal-phosphate attachment site (argD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1652Rv1656, (MTCY06H11.21), argF, len: 307. Ornithine carbamoyltransferase, anabolic, almost identical to OTCA_MYCBO Q02095 ornithine carbamoyltransferase, anabolic (307 aa), fasta scores, opt: 1980, E(): 0, (99.0% identity in 307 aa overlap); contains PS00097 Aspa (argF) {Mycobacterium tuberculosis H37Rv (lab strain)}
1653Rv1657, (MTCY06H11.22), argR, len: 170. Argine repressor, ahrC or argR, Similar to eg AHRC_BACSU P17893 arginine hydroximate resistance protein (149 aa), fasta scores, opt: 283, E(): 1.8e-11, (34.5% identity in 142 aa overlap) and arginine repressor ARGR_ECOLI (argR) {Mycobacterium tuberculosis H37Rv (lab strain)}
1654Rv1658, (MTCY06H11.23), argG, len: 398. Argininosuccinate synthase, similar to e.g. ASSY_STRCL P50986 argininosuccinate synthase (397 aa), fasta scores, opt: 1873, E(): 0, (67.8% identity in 397 aa overlap); contains PS00564 Argininosuccinate synthase signature (argG) {Mycobacterium tuberculosis H37Rv (lab strain)}
1655Rv1659, (MTCY06H11.24), argH, len: 470. Argininosuccinate lyase, similar e.g. to ARLY_ECOLI P11447 argininosuccinate lyase (ec 4.3.2.1) (457 aa), fasta scores, opt: 1091, E(): 0, (42.5% identity in 461 aa overlap); contains PS00017 ATP/GTP-binding site motif A, (argH) {Mycobacterium tuberculosis H37Rv (lab strain)}
1656Rv1660, (MTCY06H11.25), len: 353. Possible chalconesynthase, similar to eg BCSA_BACSU P54157 putative chalconesynthase (365 aa),fasta scores, opt: 701, E(): 0, (33.1% identity in 362 aa overlap), other upstream initiation sitesare possible but homology suggests (pks10) {Mycobacterium tuberculosis H37Rv (lab strain)}
1657Rv1661, (MTCY06H11.26), len: 2126. Probable polyketide synthase, similar to many e.g. ERY2_SACER Q03132 erythronolide synthase, modules 3 and 4 (3567 aa), fasta scores; E(): 0, 48.8% identity in 2131 aa overlap; contains PS00606Beta-ketoacyl synthases active si (pks7) {Mycobacterium tuberculosis H37Rv (lab strain)}
1658Rv1662, (MTCY275.01-MTCY06H11.27), len: 1602. Probable polyketide synthase, similar to many polyketide synthases eg. ERY2_SACER Q03132 erythronolide synthase, modules 3 and 4 (3567 aa) from Saccharopolyspora erythraea (Streptomyces erythraeus), fasta scores; op (pks8) {Mycobacterium tuberculosis H37Rv (lab strain)}
1659Rv1663, (MTCY275.02), len: 502 aa; Probable polyketide synthase, similar to other polyketide synthases eg. ERY2_SACER Q03132 erythronolide synthase, modules 3 and 4 (3567 aa) from Saccharopolyspora erythraea (Streptomyces erythraeus), fasta scores; opt: 1207 z- (pks17) {Mycobacterium tuberculosis H37Rv (lab strain)}
1660Rv1664, (MTCY275.03), len: 1017. Probable polyketide synthase; similar to eg. OL56_STRAT Q07017 oleandomycin polyketide synthase, modules 5 and 6 (3519 aa) from Streptomycesantibioticus, fasta scores; opt: 1767 z-score: 1880.3 E():0, 41.6% identity in 919 aa ov (pks9) {Mycobacterium tuberculosis H37Rv (lab strain)}
1661Rv1665, (MTCY275.04-MTV047.01), len 353. Some similarity to BCSA_BACSU P54157 putative chalcone synthase (365 aa), fasta scores; opt: 615 z-score: 699.3 E(): 6.2e-32,33.4% identity in 308 aa overlap, and to many plant chalcone synthases eg. CHS_VIGUN P51089 cha (pks11) {Mycobacterium tuberculosis H37Rv (lab strain)}
1662Rv1666chypothetical protein Rv1666c {Mycobacterium tuberculosis H37Rv (lab strain)}
1663Rv1667chypothetical protein Rv1667c {Mycobacterium tuberculosis H37Rv (lab strain)}
1664Rv1668chypothetical protein Rv1668c {Mycobacterium tuberculosis H37Rv (lab strain)}
1665Rv1669hypothetical protein Rv1669 {Mycobacterium tuberculosis H37Rv (lab strain)}
1666Rv1670hypothetical protein Rv1670 {Mycobacterium tuberculosis H37Rv (lab strain)}
1667Rv1671hypothetical protein Rv1671 {Mycobacterium tuberculosis H37Rv (lab strain)}
1668Rv1672chypothetical protein Rv1672c {Mycobacterium tuberculosis H37Rv (lab strain)}
1669Rv1673chypothetical protein Rv1673c {Mycobacterium tuberculosis H37Rv (lab strain)}
1670Rv1674chypothetical protein Rv1674c {Mycobacterium tuberculosis H37Rv (lab strain)}
1671Rv1675chypothetical protein Rv1675c {Mycobacterium tuberculosis H37Rv (lab strain)}
1672Rv1676hypothetical protein Rv1676 {Mycobacterium tuberculosis H37Rv (lab strain)}
1673Rv1677, (MTV047.12), len: 182.dsbF, Probable lipoprotein possibly involved in thiol:disulfide interchange, highly similar toC-terminus of M.tuberculosis mpt53 soluble secreted antigenprecursor. Also some similarity to PRECURSORS OF THIOL:DISULFIDE INTERCHANGE P (dsbF) {Mycobacterium tuberculosis H37Rv (lab strain)}
1674Rv1678hypothetical protein Rv1678 {Mycobacterium tuberculosis H37Rv (lab strain)}
1675Rv1679, (MTV047.14,MTCI125.01), len: 373. fadE16, similar to acyl/butyryl-CoA dehydrogenases e.g. gp|Z99113|BSUB0010_119 Bacillus subtilis complete genome (380 aa), FASTA scores: opt: 439 z-score: 497.4 E(): 3.4e-20; 29.6% identity in 287 aa overlap.weakly simi (fadE16) {Mycobacterium tuberculosis H37Rv (lab strain)}
1676Rv1680hypothetical protein Rv1680 {Mycobacterium tuberculosis H37Rv (lab strain)}
1677Rv1681, (MTCI125.03), len: 330. Unknown, has weak similarity to MOAA_ECOLI P30745 molybdenum cofactor biosynthesis protein (329 aa), fasta scores; opt: 162 z-score: 193.2 E(): 0.00081, 27.7% identity in 224 aa overlap and to theM. tuberculosis MoaA MTCY164.19 ( (moeX) {Mycobacterium tuberculosis H37Rv (lab strain)}
1678Rv1682hypothetical protein Rv1682 {Mycobacterium tuberculosis H37Rv (lab strain)}
1679Rv1683hypothetical protein Rv1683 {Mycobacterium tuberculosis H37Rv (lab strain)}
1680Rv1684hypothetical protein Rv1684 {Mycobacterium tuberculosis H37Rv (lab strain)}
1681Rv1685chypothetical protein Rv1685c {Mycobacterium tuberculosis H37Rv (lab strain)}
1682Rv1686chypothetical protein Rv1686c {Mycobacterium tuberculosis H37Rv (lab strain)}
1683Rv1687chypothetical protein Rv1687c {Mycobacterium tuberculosis H37Rv (lab strain)}
1684Rv1688hypothetical protein Rv1688 {Mycobacterium tuberculosis H37Rv (lab strain)}
1685Rv1689, (MTCI125.11), len: 424. Tyrosyl-tRNA synthase, highly similar to many eg. SYY_ECOLI P00951 tyrosyl-trnasynthetase (ec 6.1.1.1) (423 aa), fasta scores; opt: 1271 z-score: 1200.9 E(): 0, 47.3% identity in 419 aa overlap. Contains PS00178 Aminoacyl-transfe (tyrS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1686Rv1690, (MTCI125.12), len: 127. Unknown, contains possible signal sequence and PS00013 Prokaryotic membrane lipoprotein lipid attachment site; weakly similar to other M.tuberculosis hypothetical proteins eg. MTCY16F9.04c (32.5%identity in 114 aa overlap) (lprJ) {Mycobacterium tuberculosis H37Rv (lab strain)}
1687Rv1691hypothetical protein Rv1691 {Mycobacterium tuberculosis H37Rv (lab strain)}
1688Rv1692hypothetical protein Rv1692 {Mycobacterium tuberculosis H37Rv (lab strain)}
1689Rv1693hypothetical protein Rv1693 {Mycobacterium tuberculosis H37Rv (lab strain)}
1690Rv1694, (MTCI125.16), tlyA, len: 269. Cytotoxin/haemolysin homologue, almost identical to M. tuberculosis TR:Q50760 cytotoxin/haemolysin homologue TlyA from EMBL:MTHYPROT; also similar to HLYA_TREHY Q06803 hemolysin from treponema hyodysenteriae (240 aa), fasta (tlyA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1691Rv1695hypothetical protein Rv1695 {Mycobacterium tuberculosis H37Rv (lab strain)}
1692Rv1696, (MTCI125.18), recN, len: 587. DNA repair protein, similar to many eg. RECN_ECOLI P05824 dna repair protein recN (553 aa), fasta scores; opt: 508 z-score: 725.0 E(): 1.9e-33, 31.5% identity in 587 aa overlap. Contains PS00017 ATP/GTP-binding site motif A (recN) {Mycobacterium tuberculosis H37Rv (lab strain)}
1693Rv1697hypothetical protein Rv1697 {Mycobacterium tuberculosis H37Rv (lab strain)}
1694Rv1698hypothetical protein Rv1698 {Mycobacterium tuberculosis H37Rv (lab strain)}
1695Rv1699, (MTCI125.21), pyrG, len: 586. CTP synthase highly similar to many eg. PYRG_ECOLI P08398 ctp synthase (ec 6.3.4.2) (544 aa), fasta scores; opt: 1786 z-score: 1968.3 E():0, 51.8% identity in 548 aa overlap. Contains PS00442 Glutamine amidotransferases cla (pyrG) {Mycobacterium tuberculosis H37Rv (lab strain)}
1696Rv1700hypothetical protein Rv1700 {Mycobacterium tuberculosis H37Rv (lab strain)}
1697Rv1701hypothetical protein Rv1701 {Mycobacterium tuberculosis H37Rv (lab strain)}
1698Rv1702chypothetical protein Rv1702c {Mycobacterium tuberculosis H37Rv (lab strain)}
1699Rv1703chypothetical protein Rv1703c {Mycobacterium tuberculosis H37Rv (lab strain)}
1700Rv1704c, (MTCI125.26c), cycA, len: 556. D-serine/d-alanine/glycine transporter, highly similar to CYCA_ECOLI P39312 d-serine/d-alanine/glycine transporter (470 aa), fasta scores; opt: 1906 z-score: 2124.4 E(): 0, 59.3% identityin 459 aa overlap, and to other ami (cycA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1701Rv1705c, (MTCI125.27c), len: 385. Similar to members of the PPE family of M. tuberculosis hypothetical proteins eg. YX23_MYCTU Q10813 hypothetical 41.1 kd protein cy274.23(404 aa), fasta scores; opt: 819 z-score: 979.5 E(): 0,46.2% identity in 413 aa overlap (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1702Rv1706c, (MTCI125.28c), len: 394. Similar to members of the PPE family of M. tuberculosis proteins eg. YX23_MYCTU Q10813 hypothetical 41.1 kd protein cy274.23 (404 aa),fasta scores; opt: 841 z-score: 683.7 E(): 3.9e-31, 46.8% identity in 408 aa overlap (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1703Rv1707hypothetical protein Rv1707 {Mycobacterium tuberculosis H37Rv (lab strain)}
1704Rv1708hypothetical protein Rv1708 {Mycobacterium tuberculosis H37Rv (lab strain)}
1705Rv1709hypothetical protein Rv1709 {Mycobacterium tuberculosis H37Rv (lab strain)}
1706Rv1710hypothetical protein Rv1710 {Mycobacterium tuberculosis H37Rv (lab strain)}
1707Rv1711hypothetical protein Rv1711 {Mycobacterium tuberculosis H37Rv (lab strain)}
1708Rv1712, (MTCI125.34), cmk, len: 230. Cytidylate kinase, highly similar to many eg. KCY_ECOLI P23863 cytidylatekinase(ec2.7.4.14) (ck) (227 aa), fasta scores; opt: 534 z-score: 753.0 E(): 0, 40.3% identity in 221 aa overlap. ContainsPS00017 ATP/GTP-binding site (cmk) {Mycobacterium tuberculosis H37Rv (lab strain)}
1709Rv1713hypothetical protein Rv1713 {Mycobacterium tuberculosis H37Rv (lab strain)}
1710Rv1714hypothetical protein Rv1714 {Mycobacterium tuberculosis H37Rv (lab strain)}
1711Rv1715, (MTV048.02), len: 304; fadB3, Probable 3-hydroxybutyryl-CoA dehydrogenase, similar to many, e.g.gp|U29084|BSU29084_2 Bacillus subtilis (mmgA), (mmgB), (287 aa), FASTA scores:opt:488 z-score: 575.4 E(): 1.5e-24. 38.7% identity in 279 aaoverlap (fadB3) {Mycobacterium tuberculosis H37Rv (lab strain)}
1712Rv1716hypothetical protein Rv1716 {Mycobacterium tuberculosis H37Rv (lab strain)}
1713Rv1717hypothetical protein Rv1717 {Mycobacterium tuberculosis H37Rv (lab strain)}
1714Rv1718hypothetical protein Rv1718 {Mycobacterium tuberculosis H37Rv (lab strain)}
1715Rv1719hypothetical protein Rv1719 {Mycobacterium tuberculosis H37Rv (lab strain)}
1716Rv1720chypothetical protein Rv1720c {Mycobacterium tuberculosis H37Rv (lab strain)}
1717Rv1721chypothetical protein Rv1721c {Mycobacterium tuberculosis H37Rv (lab strain)}
1718Rv1722hypothetical protein Rv1722 {Mycobacterium tuberculosis H37Rv (lab strain)}
1719Rv1723hypothetical protein Rv1723 {Mycobacterium tuberculosis H37Rv (lab strain)}
1720Rv1724chypothetical protein Rv1724c {Mycobacterium tuberculosis H37Rv (lab strain)}
1721Rv1725chypothetical protein Rv1725c {Mycobacterium tuberculosis H37Rv (lab strain)}
1722Rv1726hypothetical protein Rv1726 {Mycobacterium tuberculosis H37Rv (lab strain)}
1723Rv1727hypothetical protein Rv1727 {Mycobacterium tuberculosis H37Rv (lab strain)}
1724Rv1728chypothetical protein Rv1728c {Mycobacterium tuberculosis H37Rv (lab strain)}
1725Rv1729chypothetical protein Rv1729c {Mycobacterium tuberculosis H37Rv (lab strain)}
1726Rv1730chypothetical protein Rv1730c {Mycobacterium tuberculosis H37Rv (lab strain)}
1727Rv1731, (MTCY04C12.16), len: 518. gabD1, Aldehyde dehydrogenase, similar eg to GABD_ECOLI P25526 succinate-semialdehyde dehydrogenase (482 aa), fasta scores, opt: 870, E(): 0, (34.7% identity in 449 aa overlap); contains PS00216Sugar transportproteins signature (gabD1) {Mycobacterium tuberculosis H37Rv (lab strain)}
1728Rv1732chypothetical protein Rv1732c {Mycobacterium tuberculosis H37Rv (lab strain)}
1729Rv1733chypothetical protein Rv1733c {Mycobacterium tuberculosis H37Rv (lab strain)}
1730Rv1734chypothetical protein Rv1734c {Mycobacterium tuberculosis H37Rv (lab strain)}
1731Rv1735chypothetical protein Rv1735c {Mycobacterium tuberculosis H37Rv (lab strain)}
1732Rv1736c, (MTCY04C12.21c), len: 652. Probable nitrate reductase. Contains three domains: N-terminus (1.250 aa) is similar to N-terminus of e.g. NARG_ECOLI P09152 respiratory nitrate reductase 1 alpha chain (1246 aa), fasta scores; E(): 0, (58.6% identity in 251 a (narX) {Mycobacterium tuberculosis H37Rv (lab strain)}
1733Rv1737c, (MTCY04C12.22c), len: 395. Possible nitrate/nitrite transporter, similar to eg NARK_BACSU P46907 nitrite extrusion protein (395 aa), fasta scores, opt: 742, E(): 0, (33.6% identity in 375 aa overlap) (narK2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1734Rv1738hypothetical protein Rv1738 {Mycobacterium tuberculosis H37Rv (lab strain)}
1735Rv1739chypothetical protein Rv1739c {Mycobacterium tuberculosis H37Rv (lab strain)}
1736Rv1740hypothetical protein Rv1740 {Mycobacterium tuberculosis H37Rv (lab strain)}
1737Rv1741hypothetical protein Rv1741 {Mycobacterium tuberculosis H37Rv (lab strain)}
1738Rv1742hypothetical protein Rv1742 {Mycobacterium tuberculosis H37Rv (lab strain)}
1739Rv1743, (MTCY28.05,MTCY04C12.28), len: 566. Probable serine/threonine protein kinase, similar to eg. PKN1_MYXXA P33973 serine/threonine-protein kinase pkn1 (693 aa), fasta scores;opt: 542 z-score: 479.2 E(): 1.1e-19. 35.8% identity in 302 aa overlap. Also highl (pknE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1740Rv1744chypothetical protein Rv1744c {Mycobacterium tuberculosis H37Rv (lab strain)}
1741Rv1745chypothetical protein Rv1745c {Mycobacterium tuberculosis H37Rv (lab strain)}
1742Rv1746, (MTCY28.09,MTCY04C12.30), len: 476. pknF Probable serine/threonine protein kinase, highly similar to eg. KY28_MYCTU Q10697 probable serine/threonine-protein kinase (589 aa),fasta scores; opt: 870 z-score: 838.4 E(): 0, 41.6% identity in 406 aa overlap. (pknF) {Mycobacterium tuberculosis H37Rv (lab strain)}
1743Rv1747hypothetical protein Rv1747 {Mycobacterium tuberculosis H37Rv (lab strain)}
1744Rv1748hypothetical protein Rv1748 {Mycobacterium tuberculosis H37Rv (lab strain)}
1745Rv1749chypothetical protein Rv1749c {Mycobacterium tuberculosis H37Rv (lab strain)}
1746Rv1750c, (MTCY28.13c-MTCY04C12.34), len: 532.fadD1,Possible coA ligase, similar to eg. CAIC_ECOLI P31552 probable crotonobetaine/carnitine-coa ligase (522 aa), fasta scores; opt: 448 z-score: 511.1 E(): 1.9e-21, 25.1% identityin 502 aa overlap. Contains PS00455 (fadD1) {Mycobacterium tuberculosis H37Rv (lab strain)}
1747Rv1751hypothetical protein Rv1751 {Mycobacterium tuberculosis H37Rv (lab strain)}
1748Rv1752hypothetical protein Rv1752 {Mycobacterium tuberculosis H37Rv (lab strain)}
1749Rv1753c, (MTCY28.16c), len: 1053. Member of PPE family of Gly-, Asn-rich proteins, similar to eg. Y04H_MYCTU Q10778 hypothetical 72.9 kd protein cy48.17. (734 aa), fastascores; opt: 1360 z-score: 1130.2 E(): 0, 48.9% identity in550 aa overlap. Note that the Gly- (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1750Rv1754chypothetical protein Rv1754c {Mycobacterium tuberculosis H37Rv (lab strain)}
1751Rv1755cProtein sequence is in conflict with the conceptual translation; Rv1755c, (MTCY28.21c), len: 203. Partial CDS for phospholipase C, highly similar to C-terminus of Q50771 phospholipaseC from M. tuberculosis (512 aa) (71.1% identity in 284 aa overlap). CDS (plcD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1752Rv1756chypothetical protein Rv1756c {Mycobacterium tuberculosis H37Rv (lab strain)}
1753Rv1757chypothetical protein Rv1757c {Mycobacterium tuberculosis H37Rv (lab strain)}
1754Rv1758hypothetical protein Rv1758 {Mycobacterium tuberculosis H37Rv (lab strain)}
1755Rv1759c, (MTCY28.25c), wag22, len: 914. Member of the PGRS family of Glycine-rich proteins, highly similar to eg. Y03A_MYCTU Q10637 hypothetical glycine-rich 49.6 kd pro(603 aa), fasta scores; opt: 2010 z-score: 1372.2 E(): 0 ,53.0% identity in 724 aa overlap. C (PE_PGRS(wag22)) {Mycobacterium tuberculosis H37Rv (lab strain)}
1756Rv1760hypothetical protein Rv1760 {Mycobacterium tuberculosis H37Rv (lab strain)}
1757Rv1761chypothetical protein Rv1761c {Mycobacterium tuberculosis H37Rv (lab strain)}
1758Rv1762chypothetical protein Rv1762c {Mycobacterium tuberculosis H37Rv (lab strain)}
1759Rv1763hypothetical protein Rv1763 {Mycobacterium tuberculosis H37Rv (lab strain)}
1760Rv1764hypothetical protein Rv1764 {Mycobacterium tuberculosis H37Rv (lab strain)}
1761Rv1765chypothetical protein Rv1765c {Mycobacterium tuberculosis H37Rv (lab strain)}
1762Rv1766hypothetical protein Rv1766 {Mycobacterium tuberculosis H37Rv (lab strain)}
1763Rv1767hypothetical protein Rv1767 {Mycobacterium tuberculosis H37Rv (lab strain)}
1764Rv1768, (MTCY28.34), len: 618 aa; member of the PEfamily, PGRS sub-family of Glycine-rich proteins, highly similar to eg. Q50615 HYPOTHETICAL 40.8 KD PROTEIN (498 aa),fasta scores; opt: 1703 z-score: 1226.8 E(): 0, 57.4% identity in 566 aa overlap (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1765Rv1769hypothetical protein Rv1769 {Mycobacterium tuberculosis H37Rv (lab strain)}
1766Rv1770hypothetical protein Rv1770 {Mycobacterium tuberculosis H37Rv (lab strain)}
1767Rv1771hypothetical protein Rv1771 {Mycobacterium tuberculosis H37Rv (lab strain)}
1768Rv1772hypothetical protein Rv1772 {Mycobacterium tuberculosis H37Rv (lab strain)}
1769Rv1773chypothetical protein Rv1773c {Mycobacterium tuberculosis H37Rv (lab strain)}
1770Rv1774hypothetical protein Rv1774 {Mycobacterium tuberculosis H37Rv (lab strain)}
1771Rv1775hypothetical protein Rv1775 {Mycobacterium tuberculosis H37Rv (lab strain)}
1772Rv1776chypothetical protein Rv1776c {Mycobacterium tuberculosis H37Rv (lab strain)}
1773Rv1777hypothetical protein Rv1777 {Mycobacterium tuberculosis H37Rv (lab strain)}
1774Rv1778chypothetical protein Rv1778c {Mycobacterium tuberculosis H37Rv (lab strain)}
1775Rv1779chypothetical protein Rv1779c {Mycobacterium tuberculosis H37Rv (lab strain)}
1776Rv1780hypothetical protein Rv1780 {Mycobacterium tuberculosis H37Rv (lab strain)}
1777Rv1781chypothetical protein Rv1781c {Mycobacterium tuberculosis H37Rv (lab strain)}
1778Rv1782hypothetical protein Rv1782 {Mycobacterium tuberculosis H37Rv (lab strain)}
1779Rv1783hypothetical protein Rv1783 {Mycobacterium tuberculosis H37Rv (lab strain)}
1780Rv1784hypothetical protein Rv1784 {Mycobacterium tuberculosis H37Rv (lab strain)}
1781Rv1785chypothetical protein Rv1785c {Mycobacterium tuberculosis H37Rv (lab strain)}
1782Rv1786hypothetical protein Rv1786 {Mycobacterium tuberculosis H37Rv (lab strain)}
1783Rv1787, (MTV049.09), len: 365. Unknown, similar to members of the PPE family of M. tuberculosis hypothetical proteins, e.g. gp|Z74024|MTCY274_24 M. tuberculosis cosmid (404 aa) FASTA scores:opt: 837 z-score: 879.6 E(): 0; 52.0%identity in 406 aa overlap, also s (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1784Rv1788, (MTV049.10), len: 99. Unknown but belongs to large family of Gly-, Ala-rich M. tuberculosis proteins (PE family), similar to e.g. gp|Z93777|MTCI364_7 M. tuberculosis cosmid (99 aa), opt: 414 z-score: 497.0 E(): 3.6e-20. 72.4% identity in 98 aa overlapAl (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1785Rv1789, (MTV049.11), len: 393. Unknown, highly similar to members of the PPE family of M. tuberculosis hypothetical proteins, e.g. gp|Z98268|MTCI125_26 M. tuberculosis cosmid (385 aa) opt: 1283 z-score: 1046.3 E(): 0, 62.7% identity in 408 aa overlap. Also simi (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1786Rv1790, (MTV049.12), len: 350. Unknown, similar to members of the PPE family of M. tuberculosis hypothetical proteins, e.g. gp|Z74024|MTCY274_24 M. tuberculosis cosmid (404 aa)FASTA scores: opt: 849 z-score: 861.0 E(): 0; 50.0% identity in 406 aa overlap. Also (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1787Rv1791, (MTV049.13), len: 99. Unknown, highly similar to members of PE family , but no glycin rich C-terminus e.g. gp|Z93777|MTCI364_7 M.tuberculosis cosmid (99 aa) opt:430 z-score: 518.1 E(): 2.4e-21; 75.5% identity in 98 aa overlap. Also similar to MTV002_35, (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1788Rv1793hypothetical protein Rv1793 {Mycobacterium tuberculosis H37Rv (lab strain)}
1789Rv1794hypothetical protein Rv1794 {Mycobacterium tuberculosis H37Rv (lab strain)}
1790Rv1795hypothetical protein Rv1795 {Mycobacterium tuberculosis H37Rv (lab strain)}
1791Rv1796hypothetical protein Rv1796 {Mycobacterium tuberculosis H37Rv (lab strain)}
1792Rv1797hypothetical protein Rv1797 {Mycobacterium tuberculosis H37Rv (lab strain)}
1793Rv1798hypothetical protein Rv1798 {Mycobacterium tuberculosis H37Rv (lab strain)}
1794Rv1799, (MTV049.21), len: 63. Unknown, probable lipoprotein has possible signal peptide and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. TBparse score is 0.904 (lppT) {Mycobacterium tuberculosis H37Rv (lab strain)}
1795Rv1800, (MTV049.22), len: 655. Member of M. tuberculosis PPE protein family, very similar to MTCI5.25c. FASTA scores: Z92770|MTCI5_25 (588 aa) opt: 1269 z-score: 1328.5 E(): 0; 41.5% identity in 591 aa overlap. TBparse score is 0.925 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1796Rv1801, (MTV049.23), len: 423. Member of the PPE family of conserved M. tuberculosis proteins, most similar toMTV002.33c (394 aa). FASTA scores: AL0089|MTV002_34 (394 aa) opt: 930 z-score: 863.7 E(): 0; 43.8% identity in 404 aa overlap. TBparse score is 0.927 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1797Rv1802, (MTV049.24), len: 463. Member of the PPE family of conserved M. tuberculosis proteins most similar to MTV002.33c (394 aa). FASTA scores: AL0089|MTV002_34 (394 aa) opt: 904 z-score: 883.8 E(): 0; 44.1% identity in 392 aa overlap. TBparse score is 0.913 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1798Rv1803c, (MTV049.25c), len: 639. Member of Mycobacterium tuberculosis PE_family, PGRS-subfamily. Most similar to MTCY28.34 (618 aa). Contains two PS00583 pfkB family of carbohydrate kinases signatures 1. FASTA scores: Z95890|MTCY28_34 (618 aa) opt: 1827 z-score: (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1799Rv1804chypothetical protein Rv1804c {Mycobacterium tuberculosis H37Rv (lab strain)}
1800Rv1805chypothetical protein Rv1805c {Mycobacterium tuberculosis H37Rv (lab strain)}
1801Rv1806, (MTV049.28), len: 99. Member of conserved Mycobacterium tuberculosis PE_family, most similar to MTCI364.07 (99 aa). FASTA scores: Z93777|MTCI364_7 (99 aa) opt:315 z-score: 429.4 E(): 2.1e-16; 54.5% identity in 99 aa overlap. TBparse score is 0.932 (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1802Rv1807, (MTV049.29), len: 403. Belongs to the M. tuberculosis PPE family, most similar to MTCY10G2.10 (391 aa). FASTA scores: Z92539|MTCY10G2_10 Mycobacterium tuberculosis cosmi (391 aa) opt: 1060 z-score: 898.4 E(): 0; 47.2% identity in 405 aa overlap. TBparse (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1803Rv1808, (MTV049.30), len: 409. Member of conserved Mycobacterium tuberculosis PPE_family, most similar to MTCY10G2.10 (391 aa). Contains PS00343 Gram-positive cocci surface proteins anchoring hexapeptide. FASTA scores: Z92539|MTCY10G2_10 (391 aa) opt: 1017 z-sc (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1804Rv1809, (MTV049.31), len: 468. Member of conserved Mycobacterium tuberculosis PPE_family, most similar to MTCY21C12.09c (423 aa). FASTA scores: Z95210|MTY21C12_9 (423 aa) opt: 921 z-score: 889.0 E(): 0; 42.4% identity in 441 aa overlap. TBparse score is 0.923 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1805Rv1810hypothetical protein Rv1810 {Mycobacterium tuberculosis H37Rv (lab strain)}
1806Rv1811, (MTCY16F9.03c), mgtC, probable magnesium transport atpase protein c, len: 234 aa; similar to eg. ATMC_SALTY P22037 mg(2+) transport atpase protein c (231 aa), fasta scores; opt: 545 z-score: 666.7 E(): 4.1e-30, 42.3% identity in 220 aa overlap (mgtC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1807Rv1812chypothetical protein Rv1812c {Mycobacterium tuberculosis H37Rv (lab strain)}
1808Rv1813chypothetical protein Rv1813c {Mycobacterium tuberculosis H37Rv (lab strain)}
1809Rv1814hypothetical protein Rv1814 {Mycobacterium tuberculosis H37Rv (lab strain)}
1810Rv1815hypothetical protein Rv1815 {Mycobacterium tuberculosis H37Rv (lab strain)}
1811Rv1816hypothetical protein Rv1816 {Mycobacterium tuberculosis H37Rv (lab strain)}
1812Rv1817hypothetical protein Rv1817 {Mycobacterium tuberculosis H37Rv (lab strain)}
1813Rv1818c, (MTCY1A11.25), len: 498, ; Member of PE-family, glycine rich PGRS-subfamily, contains 2 x PS00583 pfkB family of carbohydrate kinases signature 1 (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1814Rv1819chypothetical protein Rv1819c {Mycobacterium tuberculosis H37Rv (lab strain)}
1815Rv1820, (MTCY1A11.23c), ilvG, acetolactate synthaselen: 547, similar to eg ILVB_KLEPN P27696 (559 aa), FASTA scores, opt: 660, z-score: 739.9, E(): 2.9e-34, (29.1% identity in 549 aa overlap); contains PS00187 Thiamine pyrophosphate enzymes signature (ilvG) {Mycobacterium tuberculosis H37Rv (lab strain)}
1816Rv1821, (MTCY1A11.22c), possible translocase secA, len: 808, similar to SECA_BACSU P28366 preprotein translocase seca subunit (841 aa), FASTA scores, opt: 1424, z-score:1595.5, E(): 0, (35.9% identity in 786 aa overlap) (secA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1817Rv1822, (MTCY1A11.21c), pgsA, len: 209, similar to eg PGSA_ECOLI P06978, cdp-diacylglycerol--glycerol-3-phosphate phosphatidyltransferase (181 aa), FASTA scores, opt: 252, z-score: 291.5, E(): 2.8e-09, (29.7% identity in 175 aa overlap); contains PS00379 CDP-al (pgsA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1818Rv1823hypothetical protein Rv1823 {Mycobacterium tuberculosis H37Rv (lab strain)}
1819Rv1824hypothetical protein Rv1824 {Mycobacterium tuberculosis H37Rv (lab strain)}
1820Rv1825hypothetical protein Rv1825 {Mycobacterium tuberculosis H37Rv (lab strain)}
1821Rv1826, (MTCY1A11.17c), gcvH, len: 134, highly similar to GCSH_ECOLI P23884 glycine cleavage system h protein (129 aa), FASTA scores, opt: 428, z-score: 526.8, E(): 2.2e-22, (47.8% identity in 134 aa overlap); contains PS00189 2-oxo acid dehydrogenases acyltran (gcvH) {Mycobacterium tuberculosis H37Rv (lab strain)}
1822Rv1827hypothetical protein Rv1827 {Mycobacterium tuberculosis H37Rv (lab strain)}
1823Rv1828hypothetical protein Rv1828 {Mycobacterium tuberculosis H37Rv (lab strain)}
1824Rv1829hypothetical protein Rv1829 {Mycobacterium tuberculosis H37Rv (lab strain)}
1825Rv1830hypothetical protein Rv1830 {Mycobacterium tuberculosis H37Rv (lab strain)}
1826Rv1831hypothetical protein Rv1831 {Mycobacterium tuberculosis H37Rv (lab strain)}
1827Rv1832, (MTCY1A11.11c), gcvB, glycine decarboxylase, len: 941, highly similar to eg GCSP_ECOLI P33195 glycine dehydrogenase (decarboxylating) (957 aa), FASTA scores, opt: 2194, z-score: 2375.9, E(): 0, (55.4% identity in 961 aa overlap) (gcvB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1828Rv1833chypothetical protein Rv1833c {Mycobacterium tuberculosis H37Rv (lab strain)}
1829Rv1834hypothetical protein Rv1834 {Mycobacterium tuberculosis H37Rv (lab strain)}
1830Rv1835chypothetical protein Rv1835c {Mycobacterium tuberculosis H37Rv (lab strain)}
1831Rv1836chypothetical protein Rv1836c {Mycobacterium tuberculosis H37Rv (lab strain)}
1832Rv1837c, (MTCY1A11.06), glcB, malate synthase, len:741, highly similar to eg MASY_CORGL P42450 malate synthase(738 aa) FASTA scores, opt: 2961, z-score: 3491.7, E(): 0,(61.3% identity in 724 aa overlap)) (glcB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1833Rv1838chypothetical protein Rv1838c {Mycobacterium tuberculosis H37Rv (lab strain)}
1834Rv1839chypothetical protein Rv1839c {Mycobacterium tuberculosis H37Rv (lab strain)}
1835Rv1840c, (MTCY359.33), len: 515. Function: unknown but member of Ala, Gly-rich protein PE-family, PGRS-subfamily. FASTA best: Y03A_MYCTU Q10637 hypothetical glycine-rich49.6 kd pro (603 aa), opt: 1693, E(): 0, (53.1% identity in612 aa overlap. Similar to other M (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1836Rv1841chypothetical protein Rv1841c {Mycobacterium tuberculosis H37Rv (lab strain)}
1837Rv1842chypothetical protein Rv1842c {Mycobacterium tuberculosis H37Rv (lab strain)}
1838Rv1843c, (MTCY359.30), len: 479. Function: guaB1, inosine-5-monophosphate dehydrogenase. FASTA best: IMDH_BACSU P21879 (513 aa) opt: 904, E(): 0, (37.8% identity in 471 aa overlap). Similar to other M. tuberculosis proteins: MTCY1A11.01, MTCY78.17. TBPARSE score (guaB1) {Mycobacterium tuberculosis H37Rv (lab strain)}
1839Rv1844c, (MTCY359.29), len: 485. Function: gnd, 6-phosphogluconate dehydrogenase. FASTA best: 6PGD_ECOLI P00350 6-phosphogluconate dehydrogenase, (468 aa), opt: 1661, E(): 0, (53.6% identity in 466 aa overlap). TBPARSE score is 0.886 (gnd) {Mycobacterium tuberculosis H37Rv (lab strain)}
1840Rv1845chypothetical protein Rv1845c {Mycobacterium tuberculosis H37Rv (lab strain)}
1841Rv1846chypothetical protein Rv1846c {Mycobacterium tuberculosis H37Rv (lab strain)}
1842Rv1847hypothetical protein Rv1847 {Mycobacterium tuberculosis H37Rv (lab strain)}
1843Rv1848, (MTCY359.25c), len: 100. Function: ureA, urease gamma subunit. FASTA best: URE3_MYCTU P50043 (ec 3.5.1.5), opt: 630, E(): 1.3e-36, (99.0% identity in 100 aa overlap). TBPARSE score is 0.874 (ureA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1844Rv1849, (MTCY359.24c), len: 104. Function: ureB, urease beta subunit. Identical to URE2_MYCTU P50048 urease beta subunit (ec 3.5.1.5). TBPARSE score is 0.914 (ureB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1845Rv1850, (MTCY359.23c), len: 577. Function: ureC, urease alpha subunit; has PS00145 Urease active site motif. FASTA best: URE1_MYCTU P50042, (577 aa), opt: 3794, E(): 0, (98.3% identity in 577 aa overlap. TBPARSE score is 0.898) (ureC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1846Rv1851, (MTCY359.22c), len: 211. Function: ureF, urease accessory protein. Identical to UREF_MYCTU P50050. TBPARSE score is 0.871 (ureF) {Mycobacterium tuberculosis H37Rv (lab strain)}
1847Rv1852, (MTCY359.21c), len: 224. Function: ureG, urease accessory protein has PS00017 ATP/GTP-binding site motif A (P-loop). Identical to UREG_MYCTU P50051. TBPARSE score is 0.878 (ureG) {Mycobacterium tuberculosis H37Rv (lab strain)}
1848Rv1853, (MTCY359.20c), len: 208. Function: ureD, probable urease accessory protein. FASTA best: URED_YEREN P42868 urease operon ureD protein (325 aa), opt: 114, E(): 0.37; (25.2% identity in 119 aa overlap). TBPARSE score is 0.904 (ureD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1849Rv1854c, (MTCY359.19), len: 463. Function: ndh, probable NADH dehydrogenase, similar to several - e.g. S74826 NADH dehydrogenase - Synechocystis s (445 aa) FASTA score: opt: 1228 z-score: 1387.4 E(): 0; 46.3% identity in 432 aa overlap. Highly similar to MTCY04D (ndh) {Mycobacterium tuberculosis H37Rv (lab strain)}
1850Rv1855chypothetical protein Rv1855c {Mycobacterium tuberculosis H37Rv (lab strain)}
1851Rv1856chypothetical protein Rv1856c {Mycobacterium tuberculosis H37Rv (lab strain)}
1852Rv1857, (MTCY359.16c), modA, len: 261. Function: probable molybdate binding protein attached to membrane by lipid-modified N-terminal cysteine (contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site) shows strong similarity to precursors of per (modA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1853Rv1858, (MTCY359.15c), modB, len: 264. Function: probable transport system permease for molybdate uptake. FASTA best: Y10817|ANY108175 NID: g2288874 - Arthrobacter ModB (239 aa) opt: 937; E(): 0; 67.8% identity in 230 aa overlap.. Similar to other M. tuberculos (modB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1854Rv1859, (MTCY359.14c), modC, len: 369. Function: probable membrane-bound ABC-transporter contains both PS00017ATP/GTP-binding site motif A (P-loop) and PS00211 ABC transporters family signatures involved in molybdate uptake. FASTA best: Y10817|ANY108176 NID: g2 (modC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1855Rv1860, (MTCY359.0013), modD, len: 325. Function: Precursor of Apa, Ala-Pro rich 45/47 kDa secreted protein. Identical to G1008136 45/47 gene precursor (325 aa), also referred to as modD in submission X99258, possibly involved in molybdate uptake. Very similar (modD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1856Rv1861hypothetical protein Rv1861 {Mycobacterium tuberculosis H37Rv (lab strain)}
1857Rv1862, (MTCY359.11), adhA, len: 346. Function: probable alcohol dehydrogenase, contains PS00059 Zinc-containing alcohol dehydrogenases signature. FASTA best: ADH2_BACSTP42327 alcohol dehydrogenase (339 aa), opt: 630, E(): 2.4e-32 (34.4% identity in 320 aa over (adhA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1858Rv1863chypothetical protein Rv1863c {Mycobacterium tuberculosis H37Rv (lab strain)}
1859Rv1864chypothetical protein Rv1864c {Mycobacterium tuberculosis H37Rv (lab strain)}
1860Rv1865chypothetical protein Rv1865c {Mycobacterium tuberculosis H37Rv (lab strain)}
1861Rv1866hypothetical protein Rv1866 {Mycobacterium tuberculosis H37Rv (lab strain)}
1862Rv1867hypothetical protein Rv1867 {Mycobacterium tuberculosis H37Rv (lab strain)}
1863Rv1868hypothetical protein Rv1868 {Mycobacterium tuberculosis H37Rv (lab strain)}
1864Rv1869chypothetical protein Rv1869c {Mycobacterium tuberculosis H37Rv (lab strain)}
1865Rv1870chypothetical protein Rv1870c {Mycobacterium tuberculosis H37Rv (lab strain)}
1866Rv1871chypothetical protein Rv1871c {Mycobacterium tuberculosis H37Rv (lab strain)}
1867Rv1872c, (MTCY180.46, MTCY359.01), lldD2, probable oxidoreductase, len: 414. Similar to lactate dehydrogenase and other oxidases. Start uncertain. FASTA results: Q51135 LACTATE DEHYDROGENASE (390 aa) opt: 309; E(): 4.1e-15; 42.5% identity in 113 aa overlap. TBpa (lldD2) {Mycobacterium tuberculosis H37Rv (lab strain)}
1868Rv1873hypothetical protein Rv1873 {Mycobacterium tuberculosis H37Rv (lab strain)}
1869Rv1874hypothetical protein Rv1874 {Mycobacterium tuberculosis H37Rv (lab strain)}
1870Rv1875hypothetical protein Rv1875 {Mycobacterium tuberculosis H37Rv (lab strain)}
1871Rv1876, (MTCY180.42c), bfrA. Len: 159. Function: bacterioferritin. FASTA results: BFR_MYCLE P43315 bacterioferritin (bfr) (159 aa) opt: 958; E(): 0; 90.6% identity in 159 aa overlap. TBparse score is 0.913 (bfrA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1872Rv1877hypothetical protein Rv1877 {Mycobacterium tuberculosis H37Rv (lab strain)}
1873Rv1878, (MTCY180.40c), len: 450. glnA3, Similar to many glutamine synthetases. FASTA results: GLNA_BACCE P19064 (EC 6.3.1.2) (443 aa) opt: 497; E(): 5.2e-23; 29.0% identity in 331 aa overlap. TBparse score is 0.925. Also similarto C-terminus of FLUG_EMENI P3809 (glnA3) {Mycobacterium tuberculosis H37Rv (lab strain)}
1874Rv1879hypothetical protein Rv1879 {Mycobacterium tuberculosis H37Rv (lab strain)}
1875Rv1880chypothetical protein Rv1880c {Mycobacterium tuberculosis H37Rv (lab strain)}
1876Rv1881c, (MTCY180.37), len: 140. Possible lipoprotein, contains signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. Some similarity to L12238|MSG18S19K_1 (162 aa) opt: 137 z-score: 186.9 E(): 0.0069; 27.6% (lppE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1877Rv1882chypothetical protein Rv1882c {Mycobacterium tuberculosis H37Rv (lab strain)}
1878Rv1883chypothetical protein Rv1883c {Mycobacterium tuberculosis H37Rv (lab strain)}
1879Rv1884chypothetical protein Rv1884c {Mycobacterium tuberculosis H37Rv (lab strain)}
1880Rv1885chypothetical protein Rv1885c {Mycobacterium tuberculosis H37Rv (lab strain)}
1881Rv1886c, (MTCY180.32), fbpB, len: 325. Function: antigen 85-B precursor, mycolyl transferase, fibronectin binding protein. Related to precursors of antigen 85-A and antigen 85-C. FASTA results: A85B_MYCTU P31952 antigen 85-b precursor (85b) (325 aa) opt: 2249; E (fbpB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1882Rv1887hypothetical protein Rv1887 {Mycobacterium tuberculosis H37Rv (lab strain)}
1883Rv1888chypothetical protein Rv1888c {Mycobacterium tuberculosis H37Rv (lab strain)}
1884Rv1889chypothetical protein Rv1889c {Mycobacterium tuberculosis H37Rv (lab strain)}
1885Rv1890chypothetical protein Rv1890c {Mycobacterium tuberculosis H37Rv (lab strain)}
1886Rv1891hypothetical protein Rv1891 {Mycobacterium tuberculosis H37Rv (lab strain)}
1887Rv1892hypothetical protein Rv1892 {Mycobacterium tuberculosis H37Rv (lab strain)}
1888Rv1893hypothetical protein Rv1893 {Mycobacterium tuberculosis H37Rv (lab strain)}
1889Rv1894chypothetical protein Rv1894c {Mycobacterium tuberculosis H37Rv (lab strain)}
1890Rv1895hypothetical protein Rv1895 {Mycobacterium tuberculosis H37Rv (lab strain)}
1891Rv1896chypothetical protein Rv1896c {Mycobacterium tuberculosis H37Rv (lab strain)}
1892Rv1897chypothetical protein Rv1897c {Mycobacterium tuberculosis H37Rv (lab strain)}
1893Rv1898hypothetical protein Rv1898 {Mycobacterium tuberculosis H37Rv (lab strain)}
1894Rv1899c, (MTCY180.19), len: 343. Possibly lipoprotein contains appropriately localized lipoprotein lipid attachment site (PS00013). Some similarity to 4-hydroxybutyrate dehydrogenase. FASTA results: Q44020 4-HYDROXYBUTYRATE DEHYDROGENASE (GBD), OR (173 aa) opt: (lppD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1895Rv1900c, (MTCY180.18), len: 462. Some similarity toesterases and hypothetical M. tuberculosis proteins. FASTAresults: Q43936 BETA-KETOADIPATE ENOL-LACTONE HYDROLASE (267aa) opt: 217; E(): 1.7e-07; 29.2% identity in 260 aa overlap. Also similar to other M. tuberc (lipJ) {Mycobacterium tuberculosis H37Rv (lab strain)}
1896Rv1901, (MTCY180.17c), cinA, len: 430. Probable cinA, strong similarity to competence damage proteins CinA of B. subtilis and S. pneumoniae. FASTA results: Q55760 HYPOTHETICAL 44.7 KD PROTEIN (416 aa) opt: 755; E(): 0; 36.0% identity in 433 aa overlap. TBparse (cinA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1897Rv1902c, (MTCY180.16), len: 422. Unknown transmembrane protein, similar to NanT, the sialic acid transporter (Q48076). Contains sugar transport proteins signature 2 (PS00217). FASTA results: Q48076 SIALIC ACID TRANSPORTER (407 aa) opt: 443; E(): 5.4e-22; 26.7% i (nanT) {Mycobacterium tuberculosis H37Rv (lab strain)}
1898Rv1903hypothetical protein Rv1903 {Mycobacterium tuberculosis H37Rv (lab strain)}
1899Rv1904hypothetical protein Rv1904 {Mycobacterium tuberculosis H37Rv (lab strain)}
1900Rv1905c, (MTCY180.13), len: 320. aao, Probable amino acid oxidase. Equivalent to Mycobacterium leprae AJ000521|MLCOSL672_2 (320 aa). FASTA results: AJ000521|MLCOSL672_2 (320 aa) opt: 1541 z-score: 1724.3 E(): 0; 71.7% identity in 315 aa overlapand OXDD_BOVIN P31 (aao) {Mycobacterium tuberculosis H37Rv (lab strain)}
1901Rv1906chypothetical protein Rv1906c {Mycobacterium tuberculosis H37Rv (lab strain)}
1902Rv1907chypothetical protein Rv1907c {Mycobacterium tuberculosis H37Rv (lab strain)}
1903Rv1908c, (MTCY180.10), len: 740. Function: KatG, catalase-peroxidase (EC 1.11.1.6), HPI. Contains peroxidases active site signature (PS00436) and ATP/GTP-binding site motif A (P-loop; PS00017). Cosmid sequence was corrected to agree with a sequencing read from t (katG) {Mycobacterium tuberculosis H37Rv (lab strain)}
1904Rv1909c, (MTCY180.09), len: 150. furA, similar to family of ferric uptake regulatory proteins. FASTA results: Q48835 LEGIONELLA PNEUMOPHILA 130B (WADSWORTH) FERRIC UPTAKE REGULATION (136 aa) opt: 230; E(): 2.5e-09; 32.3% identity in 133 aa overlap. (furA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1905Rv1910chypothetical protein Rv1910c {Mycobacterium tuberculosis H37Rv (lab strain)}
1906Rv1911c, (MTCY180.07), len: 201. Probably lipoprotein contains appropriately positioned prokaryotic membrane lipoprotein lipid attachment site (PS00013). Very similar todownstream ORF MTCY180.08, (204 aa) although this lacks lipoprotein motif. FASTA score: opt: (lppC) {Mycobacterium tuberculosis H37Rv (lab strain)}
1907Rv1912c, (MTCY180.06), len: 334. fadB5, Possible oxidoreductase, similar to hydroxyacyl-CoA dehydrogenase, quinone oxidoreductases (EC 1.6.5.5) and polyketide synthases.Contains quinone oxidoreductase / zeta-crystallin signature(PS01162). FASTA results: Q53927 H (fadB5) {Mycobacterium tuberculosis H37Rv (lab strain)}
1908Rv1913hypothetical protein Rv1913 {Mycobacterium tuberculosis H37Rv (lab strain)}
1909Rv1914chypothetical protein Rv1914c {Mycobacterium tuberculosis H37Rv (lab strain)}
1910Rv1915, (MTCY180.03c), len: 367 aa. aceAa. Probableisocitrate lyase (EC 4.1.3.1). Highly similar to the N-terminus of ACEA_MYCLE. Although this ORF and the downstream ORF representing the C-terminal half of aceA could be joinedby a frameshift no error is appare (aceAa) {Mycobacterium tuberculosis H37Rv (lab strain)}
1911Rv1916, (MTCY180.02c), len: 398 aa. aceAb. Probableisocitrate lyase (EC 4.1.3.1). Highly similar to the C-terminus of ACEA_MYCLE. Although this ORF and the upstream ORFrepresenting the N-terminal half of aceA could be joined by a frameshift no error is apparent (aceAb) {Mycobacterium tuberculosis H37Rv (lab strain)}
1912Rv1917c, (MTV050.01c-MTCY180.01), len: 1436. Unknown but member of the Gly, Asn-rich MPTR (PPE) family similarto MTCY28_16, MTCY13E10_17, MTCY63_10, MTV004_5, MTCY98_24, MTCY6G11_5, etc.C-terminus is identical to Q50471. FASTAresults: Q50471 ORF 5 OF KATG {SPECI (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1913Rv1918c, (MTV050.02c), len: 987. Unknown, member ofPPE family of Gly-, Asn-rich proteins. Similar to MTCY28_16, FASTA scores: gp|Z95890|MTCY28_16 M. tuberculosis cosmid (1053 aa), opt: 3404 z-score: 2836.8 E(): 0; 65.6% identityin 1058 aa overlap. Also similar t (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
1914Rv1919chypothetical protein Rv1919c {Mycobacterium tuberculosis H37Rv (lab strain)}
1915Rv1920hypothetical protein Rv1920 {Mycobacterium tuberculosis H37Rv (lab strain)}
1916Rv1921c, (MTCY09F9.43-MTV050.05c), len: 423. Lipoprotein, similar to G403173 lipoprotein precursor (fragment) (225 aa), fasta scores, opt: 364, E(): 9.2e-19, (41.9% identity in 148 aa overlap); contains PS00013 Prokaryotic membrane lipoprotein lipid attachment s (lppF) {Mycobacterium tuberculosis H37Rv (lab strain)}
1917Rv1922hypothetical protein Rv1922 {Mycobacterium tuberculosis H37Rv (lab strain)}
1918Rv1923, (MTCY09F9.41c), len: 446 aa. Similar to esterases, beta-lactamases, eg G151214 esterase, (389 aa), fasta scores, opt: 569, E(): 5.4e-29, (33.7% identity in 401 aa overlap) also MTCY277.19 (56.6% identity in 410 aa overlap) (lipD) {Mycobacterium tuberculosis H37Rv (lab strain)}
1919Rv1924chypothetical protein Rv1924c {Mycobacterium tuberculosis H37Rv (lab strain)}
1920Rv1925, (MTCY09F9.39c), len: 620 aa. fadD31 Acyl-CoA synthase similar to eg Y06J_MYCTU Q10976 hypothetical 67.9 kd protein cy338.19 (626 aa), fasta scores, opt: 945, E(): 0, (39.8% identity in 598 aa overlap), also G1171128 SAFRAMYCIN MX1 SYNTHETASE B(1770 aa), (fadD31) {Mycobacterium tuberculosis H37Rv (lab strain)}
1921Rv1926chypothetical protein Rv1926c {Mycobacterium tuberculosis H37Rv (lab strain)}
1922Rv1927hypothetical protein Rv1927 {Mycobacterium tuberculosis H37Rv (lab strain)}
1923Rv1928chypothetical protein Rv1928c {Mycobacterium tuberculosis H37Rv (lab strain)}
1924Rv1929chypothetical protein Rv1929c {Mycobacterium tuberculosis H37Rv (lab strain)}
1925Rv1930chypothetical protein Rv1930c {Mycobacterium tuberculosis H37Rv (lab strain)}
1926Rv1931chypothetical protein Rv1931c {Mycobacterium tuberculosis H37Rv (lab strain)}
1927Rv1932, (MTCY09F9.32c), len: 165 aa. tpx. Probable thiol peroxidase similar to eg TPX_ECOLI P37901 thiol peroxidase, (ec 1.11.1.-) (p20) (167 aa), fasta scores, opt: 535, E(): 7.3e-25, (52.4% identity in 164 aa overlap) (tpx) {Mycobacterium tuberculosis H37Rv (lab strain)}
1928Rv1933c, (MTCY09F9.31), len: 363 aa. fadE18. Acyl-CoA dehydrogenase similar to ACDS_RAT P15651 acyl-coa dehydrogenase, short-chain specific (412 aa), fasta scores, opt: 239, E(): 2.1e-08, (28.4% identity in 331 aa overlap) (fadE18) {Mycobacterium tuberculosis H37Rv (lab strain)}
1929Rv1934c, (MTCY09F9.30), len: 409 aa. fadE17 Acyl-CoA dehydrogenase similar to Acyl-CoA dehydrogenases, eg ACD_MYCLE P46703 acyl-coa dehydrogenase (389 aa), fasta scores,opt: 414, E(): 2.6e-19, (28.3% identity in 407 aa overlap) (fadE17) {Mycobacterium tuberculosis H37Rv (lab strain)}
1930Rv1935c, (MTCY09F9.29), len: 318 aa. echA13 enoyl-CoA hydratase similar to eg ECHM_RAT P14604 enoyl-coa hydratase, mitochondrial prec (290 aa), fasta scores, opt: 228, E(): 1.2e-08, (31.0% identity in 258 aa overlap) (echA13) {Mycobacterium tuberculosis H37Rv (lab strain)}
1931Rv1936hypothetical protein Rv1936 {Mycobacterium tuberculosis H37Rv (lab strain)}
1932Rv1937hypothetical protein Rv1937 {Mycobacterium tuberculosis H37Rv (lab strain)}
1933Rv1938, (MTCY09F9.26c), len: 356 aa. ephB - Epoxidehydrolase, similar to eg G1109600 ATSEH (EC 3.3.2.3) (321 aa), fasta scores, opt: 442, E(): 1.2e-21 (33.1% identity in356 aa overlap) (ephB) {Mycobacterium tuberculosis H37Rv (lab strain)}
1934Rv1939hypothetical protein Rv1939 {Mycobacterium tuberculosis H37Rv (lab strain)}
1935Rv1940, (MTCY09F9.24c), len: 353 aa, similar to eg GCH2_BACSU P17620 gtp cyclohydrolase ii (ec 3.5.4.25) (398 aa), fasta scores, opt: 682, E(): 0, (37.7% identity in 363aa overlap), also similar to MTCY21B4.33 (45.4% identity in368 aa overlap) (ribA) {Mycobacterium tuberculosis H37Rv (lab strain)}
1936Rv1941hypothetical protein Rv1941 {Mycobacterium tuberculosis H37Rv (lab strain)}
1937Rv1942chypothetical protein Rv1942c {Mycobacterium tuberculosis H37Rv (lab strain)}
1938Rv1943chypothetical protein Rv1943c {Mycobacterium tuberculosis H37Rv (lab strain)}
1939Rv1944chypothetical protein Rv1944c {Mycobacterium tuberculosis H37Rv (lab strain)}
1940Rv1945hypothetical protein Rv1945 {Mycobacterium tuberculosis H37Rv (lab strain)}
1941Rv1946c, (MTCY09F9.18), len: 150 aa. Possible lipoprotein, contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site, some similarity to MTCY09F9.21 (71.4%identity in 28 aa overlap) (lppG) {Mycobacterium tuberculosis H37Rv (lab strain)}
1942Rv1947hypothetical protein Rv1947 {Mycobacterium tuberculosis H37Rv (lab strain)}
1943Rv1948chypothetical protein Rv1948c {Mycobacterium tuberculosis H37Rv (lab strain)}
1944Rv1949chypothetical protein Rv1949c {Mycobacterium tuberculosis H37Rv (lab strain)}
1945Rv1950chypothetical protein Rv1950c {Mycobacterium tuberculosis H37Rv (lab strain)}
1946Rv1951chypothetical protein Rv1951c {Mycobacterium tuberculosis H37Rv (lab strain)}
1947Rv1952hypothetical protein Rv1952 {Mycobacterium tuberculosis H37Rv (lab strain)}
1948Rv1953hypothetical protein Rv1953 {Mycobacterium tuberculosis H37Rv (lab strain)}
1949Rv1954chypothetical protein Rv1954c {Mycobacterium tuberculosis H37Rv (lab strain)}
1950Rv1955hypothetical protein Rv1955 {Mycobacterium tuberculosis H37Rv (lab strain)}
1951Rv1956hypothetical protein Rv1956 {Mycobacterium tuberculosis H37Rv (lab strain)}
1952Rv1957hypothetical protein Rv1957 {Mycobacterium tuberculosis H37Rv (lab strain)}
1953Rv1958chypothetical protein Rv1958c {Mycobacterium tuberculosis H37Rv (lab strain)}
1954Rv1959chypothetical protein Rv1959c {Mycobacterium tuberculosis H37Rv (lab strain)}
1955Rv1960chypothetical protein Rv1960c {Mycobacterium tuberculosis H37Rv (lab strain)}
1956Rv1961hypothetical protein Rv1961 {Mycobacterium tuberculosis H37Rv (lab strain)}
1957Rv1962chypothetical protein Rv1962c {Mycobacterium tuberculosis H37Rv (lab strain)}
1958Rv1963chypothetical protein Rv1963c {Mycobacterium tuberculosis H37Rv (lab strain)}
1959Rv1964hypothetical protein Rv1964 {Mycobacterium tuberculosis H37Rv (lab strain)}
1960Rv1965hypothetical protein Rv1965 {Mycobacterium tuberculosis H37Rv (lab strain)}
1961Rv1966, (MTV051.04), len: 425. Mce3 - unknown but member of Mycobacterium tuberculosis Mce protein family, similar to Mcep2, MTCY19H5.33c (404 aa), highly similar to TR:P72013 M. tuberculosis Mcep protein (EM_BA:MTMCE X70901). FASTA scores: Z97182|MTCY19H5_33 ( (mce3) {Mycobacterium tuberculosis H37Rv (lab strain)}
1962Rv1967hypothetical protein Rv1967 {Mycobacterium tuberculosis H37Rv (lab strain)}
1963Rv1968hypothetical protein Rv1968 {Mycobacterium tuberculosis H37Rv (lab strain)}
1964Rv1969hypothetical protein Rv1969 {Mycobacterium tuberculosis H37Rv (lab strain)}
1965Rv1970, (MTV051.08), len: 377. lprM, similar to several hypothetical Mycobacterium tuberculosis lipoproteins e.g. MTCI28.13 (390 aa) and MTCY19H5.29c (402 aa). and MTV023.02c. Contains possible signal sequence and PS00013 Prokaryotic membrane lipoprotein lipid (lprM) {Mycobacterium tuberculosis H37Rv (lab strain)}
1966Rv1971hypothetical protein Rv1971 {Mycobacterium tuberculosis H37Rv (lab strain)}
1967Rv1972hypothetical protein Rv1972 {Mycobacterium tuberculosis H37Rv (lab strain)}
1968Rv1973hypothetical protein Rv1973 {Mycobacterium tuberculosis H37Rv (lab strain)}
1969Rv1974hypothetical protein Rv1974 {Mycobacterium tuberculosis H37Rv (lab strain)}
1970Rv1975hypothetical protein Rv1975 {Mycobacterium tuberculosis H37Rv (lab strain)}
1971Rv1976chypothetical protein Rv1976c {Mycobacterium tuberculosis H37Rv (lab strain)}
1972Rv1977hypothetical protein Rv1977 {Mycobacterium tuberculosis H37Rv (lab strain)}
1973Rv1978hypothetical protein Rv1978 {Mycobacterium tuberculosis H37Rv (lab strain)}
1974Rv1979chypothetical protein Rv1979c {Mycobacterium tuberculosis H37Rv (lab strain)}
1975Rv1980c, (MTCY39.39), len: 228. mpt64 identical to MPB6_MYCBO P19996 immunogenic protein mpb64/mpt64 (228 aa).Similar to Rv3036c, (MTV012.51c) (mpt64) {Mycobacterium tuberculosis H37Rv (lab strain)}
1976Rv1981c, (MTCY39.38), ribonucleotide reductase small subunit, len: 322, highly similar to RIR4_SALTY P17424, ribonucleoside-diphosphate reductase (319 aa) FASTA scores, opt: 1402, z-score: 1716.0, E(): 0, (66.0% identity in 315 aa overlap); Also similar to Rv304 (nrdF) {Mycobacterium tuberculosis H37Rv (lab strain)}
1977Rv1982chypothetical protein Rv1982c {Mycobacterium tuberculosis H37Rv (lab strain)}
1978Rv1983, (MTCY39.36c), len: 558; Member of M. tuberculosis PE_PGRS family. Contains PS00141 Eukaryotic and viral aspartyl proteases active site; similar to MTCY130.10c, (43.3% identity in 522 aa overlap) (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
1979Rv1984chypothetical protein Rv1984c {Mycobacterium tuberculosis H37Rv (lab strain)}
1980Rv1985chypothetical protein Rv1985c {Mycobacterium tuberculosis H37Rv (lab strain)}
1981Rv1986hypothetical protein Rv1986 {Mycobacterium tuberculosis H37Rv (lab strain)}
1982Rv1987hypothetical protein Rv1987 {Mycobacterium tuberculosis H37Rv (lab strain)}
1983Rv1988hypothetical protein Rv1988 {Mycobacterium tuberculosis H37Rv (lab strain)}
1984Rv1989chypothetical protein Rv1989c {Mycobacterium tuberculosis H37Rv (lab strain)}
1985Rv1990chypothetical protein Rv1990c {Mycobacterium tuberculosis H37Rv (lab strain)}
1986Rv1991chypothetical protein Rv1991c {Mycobacterium tuberculosis H37Rv (lab strain)}
1987Rv1992c, (MTCY39.27), len: 771, ctpG, probable cation transport ATPase, most similar to YHHO_ECOLI P37617 hypothetical 76.8 kd protein (732 aa) FASTA scores, opt: 1229, z-score: 1332.1, E(): 0, (35.6% identity in 677 aa overlap); contains PS00435 Peroxidases pro (ctpG) {Mycobacterium tuberculosis H37Rv (lab strain)}
1988Rv1993chypothetical protein Rv1993c {Mycobacterium tuberculosis H37Rv (lab strain)}
1989Rv1994chypothetical protein Rv1994c {Mycobacterium tuberculosis H37Rv (lab strain)}
1990Rv1995hypothetical protein Rv1995 {Mycobacterium tuberculosis H37Rv (lab strain)}
1991Rv1996hypothetical protein Rv1996 {Mycobacterium tuberculosis H37Rv (lab strain)}
1992Rv1997, (MTCY39.22c-MTCY39.21c), len: 905. ctpF, probable cation transport ATPase,similar to ATA1_SYNY3 P37367cation-transporting atpase pma1 (915 aa) FASTA scores, opt:2392, z-score: 2578.1, E(): 0, (46.5% identity in 852 aa overlap); contains PS00154 E1-E2 AT (ctpF) {Mycobacterium tuberculosis H37Rv (lab strain)}
1993Rv1998chypothetical protein Rv1998c {Mycobacterium tuberculosis H37Rv (lab strain)}
1994Rv1999chypothetical protein Rv1999c {Mycobacterium tuberculosis H37Rv (lab strain)}
1995Rv2000hypothetical protein Rv2000 {Mycobacterium tuberculosis H37Rv (lab strain)}
1996Rv2001hypothetical protein Rv2001 {Mycobacterium tuberculosis H37Rv (lab strain)}
1997Rv2002, (MTCY39.16c), len: 260, fabG3, similar to 2BHD_STREX P19992 20-beta-hydroxysteroid dehydrogenase (255aa) and many mycobacterial proteins. FASTA scores, opt: 718, z-score: 807.5, E(): 2e-38, (49.8% identity in 243 aa overlap), contains PS00061 Short-chai (fabG3) {Mycobacterium tuberculosis H37Rv (lab strain)}
1998Rv2003chypothetical protein Rv2003c {Mycobacterium tuberculosis H37Rv (lab strain)}
1999Rv2004chypothetical protein Rv2004c {Mycobacterium tuberculosis H37Rv (lab strain)}
2000Rv2005chypothetical protein Rv2005c {Mycobacterium tuberculosis H37Rv (lab strain)}
2001Rv2006, (MTCY39.11c), len: 1327, some similarity toOTSB_ECOLI P31678 trehalose-phosphatase (266 aa) and M. leprae TREHALOSE-PHOSPHATASE Q49734 (429 aa). FASTA scores, sp|Q49734|Q49734 PUTATIVE TREHALOSE-PHOSPHATASE (EC 3. (429aa) opt: 1283 z-score: 1507.4 E(): (otsB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2002Rv2007c, (MTCY39.10), len: 114, fdxA ferredoxin, similar to eg FER_MYCSM P00215 ferredoxin, Mycobacterium smegmatis (106 aa) FASTA scores, opt: 448 z-score: 503.8, E(): 1.6e-21, (58.7% identity in 109 aa overlap), also similar to MTCY31.14, (34.2% identity in 11 (fdxA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2003Rv2008chypothetical protein Rv2008c {Mycobacterium tuberculosis H37Rv (lab strain)}
2004Rv2009hypothetical protein Rv2009 {Mycobacterium tuberculosis H37Rv (lab strain)}
2005Rv2010hypothetical protein Rv2010 {Mycobacterium tuberculosis H37Rv (lab strain)}
2006Rv2011chypothetical protein Rv2011c {Mycobacterium tuberculosis H37Rv (lab strain)}
2007Rv2012hypothetical protein Rv2012 {Mycobacterium tuberculosis H37Rv (lab strain)}
2008Rv2013hypothetical protein Rv2013 {Mycobacterium tuberculosis H37Rv (lab strain)}
2009Rv2014hypothetical protein Rv2014 {Mycobacterium tuberculosis H37Rv (lab strain)}
2010Rv2015chypothetical protein Rv2015c {Mycobacterium tuberculosis H37Rv (lab strain)}
2011Rv2016hypothetical protein Rv2016 {Mycobacterium tuberculosis H37Rv (lab strain)}
2012Rv2017hypothetical protein Rv2017 {Mycobacterium tuberculosis H37Rv (lab strain)}
2013Rv2018hypothetical protein Rv2018 {Mycobacterium tuberculosis H37Rv (lab strain)}
2014Rv2019hypothetical protein Rv2019 {Mycobacterium tuberculosis H37Rv (lab strain)}
2015Rv2020chypothetical protein Rv2020c {Mycobacterium tuberculosis H37Rv (lab strain)}
2016Rv2021chypothetical protein Rv2021c {Mycobacterium tuberculosis H37Rv (lab strain)}
2017Rv2022chypothetical protein Rv2022c {Mycobacterium tuberculosis H37Rv (lab strain)}
2018Rv2023chypothetical protein Rv2023c {Mycobacterium tuberculosis H37Rv (lab strain)}
2019Rv2024chypothetical protein Rv2024c {Mycobacterium tuberculosis H37Rv (lab strain)}
2020Rv2025chypothetical protein Rv2025c {Mycobacterium tuberculosis H37Rv (lab strain)}
2021Rv2026chypothetical protein Rv2026c {Mycobacterium tuberculosis H37Rv (lab strain)}
2022Rv2027chypothetical protein Rv2027c {Mycobacterium tuberculosis H37Rv (lab strain)}
2023Rv2028chypothetical protein Rv2028c {Mycobacterium tuberculosis H37Rv (lab strain)}
2024Rv2029c, (MTV018.16c), len: 339. Probable carbohydrate kinase similar to phosphofructokinase P06999|K6P2_ECOLI(309 aa) and phosphotagatosekinase LACC_STRMU (310 aa). Contains PS00583 pfkB family of carbohydrate kinases signature1. FASTA scores: P06999|K6P2_ECOLI (pfkB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2025Rv2030chypothetical protein Rv2030c {Mycobacterium tuberculosis H37Rv (lab strain)}
2026Rv2031c, (MTV018.18c), len: 144. hspX. Identical to14 KD ANTIGEN (16 KD ANTIGEN) (HSP 16.3) of M. tuberculosis. BELONGS TO THE SMALL HEAT SHOCK PROTEIN (HSP20) FAMILY. (See J. BACTERIOL. 174:1352-1359(1992); INFECT. IMMUN. 60:2066-2074(1992)). FASTA scores: P302 (hspX) {Mycobacterium tuberculosis H37Rv (lab strain)}
2027Rv2032hypothetical protein Rv2032 {Mycobacterium tuberculosis H37Rv (lab strain)}
2028Rv2033chypothetical protein Rv2033c {Mycobacterium tuberculosis H37Rv (lab strain)}
2029Rv2034hypothetical protein Rv2034 {Mycobacterium tuberculosis H37Rv (lab strain)}
2030Rv2035hypothetical protein Rv2035 {Mycobacterium tuberculosis H37Rv (lab strain)}
2031Rv2036hypothetical protein Rv2036 {Mycobacterium tuberculosis H37Rv (lab strain)}
2032Rv2037chypothetical protein Rv2037c {Mycobacterium tuberculosis H37Rv (lab strain)}
2033Rv2038chypothetical protein Rv2038c {Mycobacterium tuberculosis H37Rv (lab strain)}
2034Rv2039chypothetical protein Rv2039c {Mycobacterium tuberculosis H37Rv (lab strain)}
2035Rv2040chypothetical protein Rv2040c {Mycobacterium tuberculosis H37Rv (lab strain)}
2036Rv2041chypothetical protein Rv2041c {Mycobacterium tuberculosis H37Rv (lab strain)}
2037Rv2042chypothetical protein Rv2042c {Mycobacterium tuberculosis H37Rv (lab strain)}
2038Rv2043c, (MTV018.30c), pncA, len: 186. Identical toPYRAZINAMIDASE/NICOTINAMIDASE involved in susceptibility orresistance to antituberculous drug pyrazinamide. FASTA scores: sptr|Q50575|Q50575 PYRAZINAMIDASE/NICOTINAMIDASE. (186aa) opt: 1236 z-score: 1477.8 E(): (pncA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2039Rv2044chypothetical protein Rv2044c {Mycobacterium tuberculosis H37Rv (lab strain)}
2040Rv2045c, (MTV018.32c), len: 511. Probable carboxylesterase similar to many e.g.O08472 (489 aa) and P37967|PNBA_BACSU (489 aa). PARA-NITROBENZYL ESTERASE (EC 3.1.1.-). Contains PS00941 Carboxylesterases type-B signature 2. Contains PS00122 Carboxylesterases type- (lipT) {Mycobacterium tuberculosis H37Rv (lab strain)}
2041Rv2046, (MTV018.33), len: 218. Probable lipoproteincontains signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site.TBparse score is 0.898 (lppI) {Mycobacterium tuberculosis H37Rv (lab strain)}
2042Rv2047chypothetical protein Rv2047c {Mycobacterium tuberculosis H37Rv (lab strain)}
2043Rv2048c, (MTV018.35c), len: 4151.Probable polyketide synthase similar to many polyketide synthases e.g. the second and third modules of polyketide synthase from S erythraea (3567 aa), many other Streptomyces enzymes and putativeM. tuberculosis polyketide synthas (pks12) {Mycobacterium tuberculosis H37Rv (lab strain)}
2044Rv2049chypothetical protein Rv2049c {Mycobacterium tuberculosis H37Rv (lab strain)}
2045Rv2050hypothetical protein Rv2050 {Mycobacterium tuberculosis H37Rv (lab strain)}
2046Rv2051chypothetical protein Rv2051c {Mycobacterium tuberculosis H37Rv (lab strain)}
2047Rv2052chypothetical protein Rv2052c {Mycobacterium tuberculosis H37Rv (lab strain)}
2048Rv2053chypothetical protein Rv2053c {Mycobacterium tuberculosis H37Rv (lab strain)}
2049Rv2054hypothetical protein Rv2054 {Mycobacterium tuberculosis H37Rv (lab strain)}
2050Rv2055c, (MTCY63A.05), rpsR2. len: 88. Function: probable ribosomal protein S18. FASTA results: RR18_ODOSI P49505 chloroplast 30s ribosomal protein s18 (72 aa) opt: 209;E(): 4.7e-09; 51.6% identity in 64 aa overlap. TBparse score is 0.907. Also similar to M. tub (rpsR2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2051Rv2056c, (MTCY63A.04), rpsN2. len: 101. Function: Probable ribosomal protein S14. FASTA results: RS14_ECOLI P02370 30s ribosomal protein s14 (100 aa) opt: 290; E(): 1.7e-13; 46.0% identity in 100 aa overlap. TBparse score is 0.907. Also similar to M. tuberculosi (rpsN2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2052Rv2057c, (MTCY63A.03), rpmG. len: 54. Function: probable ribosomal protein L33. FASTA results: RL33_ECOLI P02436 50s ribosomal protein l33 (54 aa) opt: 183; E(): 1.6e-09; 51.0% identity in 49 aa overlap. TBparse score is 0.86 (rpmG) {Mycobacterium tuberculosis H37Rv (lab strain)}
2053Rv2058c, (MTCY63A.02), rpmB2. len: 78. Function: probable ribosomal protein l28, very similar to rl28 of M. tuberculosis. FASTA results: RL28_MYCTU Q10879 50s ribosomal protein l28. mycobacter (94 aa) opt: 338; E(): 9.8e-19; 64.9% identity in 77 aa overlap. TBpa (rpmB2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2054Rv2059hypothetical protein Rv2059 {Mycobacterium tuberculosis H37Rv (lab strain)}
2055Rv2060hypothetical protein Rv2060 {Mycobacterium tuberculosis H37Rv (lab strain)}
2056Rv2061chypothetical protein Rv2061c {Mycobacterium tuberculosis H37Rv (lab strain)}
2057Rv2062c, (MTCY49.01c-MTV019.03), len: 1194. cobN - very similar to COBN_PSEDE P29929 cobn protein. Pseudomonasdenitrifica (1275 aa) FASTA scores, opt: 831, z-score: 905.8, E(): 0, (37.5% identity in 983 aa overlap). Also similar to several Mg2+-chelatases e.g. H (cobN) {Mycobacterium tuberculosis H37Rv (lab strain)}
2058Rv2063chypothetical protein Rv2063c {Mycobacterium tuberculosis H37Rv (lab strain)}
2059Rv2064, (MTCY49.03), len: 363, Some similarity to COBG_PSEDE P21637 cobg protein. pseudomona (459 aa) FASTA scores, opt: 240, z-score: 271.9, E(): 1.3e-08, (27.5% identity in 407 aa overlap); contains PS01156 TonB-dependent receptor proteins signature 2 (cobG) {Mycobacterium tuberculosis H37Rv (lab strain)}
2060Rv2065, (MTCY49.04), len: 208, Probable cobH, similar to COBH_PSEDE P21638 precorrin isomerase, (210 aa), FASTA scores, opt: 750, z-score: 871.3, E(): 0, (55.4% identityin 202 aa overlap) (cobH) {Mycobacterium tuberculosis H37Rv (lab strain)}
2061Rv2066, (MTCY49.05), unknown, len: 508, Probable CobI-CobJ fusion protein. Similar in N-terminal half (aa 1-240) to COBI_PSEDE P21639, s-adenosyl-l-methionine--precorrin-2 methyl transferase (244 aa) and in C-terminal half (aa 240-508) to COBJ_PSEDE PRECORRIN-3 (cobI) {Mycobacterium tuberculosis H37Rv (lab strain)}
2062Rv2067chypothetical protein Rv2067c {Mycobacterium tuberculosis H37Rv (lab strain)}
2063Rv2068c, (MTCY49.07c), len: 307. Probable blaC, class A beta-lactamase, similar to eg BLAC_NOCLA Q06316 beta-lactamase precursor (302 aa) FASTA scores, opt: 860, z-score: 980.1, E(): 0, (50.2% identity in 283 aa overlap); contains PS00013 Prokaryotic lipid attac (blaC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2064Rv2069, (MTCY49.08), len: 185, Probable sigC RNA polymerase sigma factor similarity to SIGX_BACSU P35165 probable rna polymerase sigma factor, (194 aa) FASTA scores, opt: 218, z-score: 245.3, E(): 4.1e-07, (32.6% identity in 129 aa overlap) (sigC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2065Rv2070c, (MTCY49.09c), len: 244. Probable cobK, probable precorrin-6x reductase, L21196|RERCOBLMK3 RERCOBLMK NID: g347169 - Rhodococcus sp. NI86/21 (248 aa) opt: 792 E(): 0; (53.6% identity in 250 aa overlap), also similarity to CBIJ_SALTY Q05591 cbij protein. s (cobK) {Mycobacterium tuberculosis H37Rv (lab strain)}
2066Rv2071c, (MTCY49.10c), len: 251. Probable cobM, precorrin-3 methylase, similar to L21196|RERCOBLMK2 RERCOBLMKNID: g347169 - Rhodococococcus sp. NI86/21 (249 aa) opt:992 E(): 0; (62.4% identity in 245 aa overlap) and to COBM_PSEDE P21922 precorrin-3 methylase (25 (cobM) {Mycobacterium tuberculosis H37Rv (lab strain)}
2067Rv2072c, (MTCY49.11c), len: 390. Probable cobL, methyl transferase, similar to L21196|RERCOBLMK1 NID: g347169- Rhodocococcus sp. NI86/21 (447 aa) opt: 892 E(): 0; (50.1% identity in 369 aa overlap), and to COBL_PSEDE P21921precorrin-6y methylase (413 aa) FASTA s (cobL) {Mycobacterium tuberculosis H37Rv (lab strain)}
2068Rv2073chypothetical protein Rv2073c {Mycobacterium tuberculosis H37Rv (lab strain)}
2069Rv2074hypothetical protein Rv2074 {Mycobacterium tuberculosis H37Rv (lab strain)}
2070Rv2075chypothetical protein Rv2075c {Mycobacterium tuberculosis H37Rv (lab strain)}
2071Rv2076chypothetical protein Rv2076c {Mycobacterium tuberculosis H37Rv (lab strain)}
2072Rv2077chypothetical protein Rv2077c {Mycobacterium tuberculosis H37Rv (lab strain)}
2073Rv2078hypothetical protein Rv2078 {Mycobacterium tuberculosis H37Rv (lab strain)}
2074Rv2079hypothetical protein Rv2079 {Mycobacterium tuberculosis H37Rv (lab strain)}
2075Rv2080, (MTCY49.19), unknown, len: 187. Possible lipoprotein, contains prokayotic lipoprotein modification site (PS00013) and signal sequence at N-terminus. (lppJ) {Mycobacterium tuberculosis H37Rv (lab strain)}
2076Rv2081chypothetical protein Rv2081c {Mycobacterium tuberculosis H37Rv (lab strain)}
2077Rv2082hypothetical protein Rv2082 {Mycobacterium tuberculosis H37Rv (lab strain)}
2078Rv2083hypothetical protein Rv2083 {Mycobacterium tuberculosis H37Rv (lab strain)}
2079Rv2084hypothetical protein Rv2084 {Mycobacterium tuberculosis H37Rv (lab strain)}
2080Rv2085hypothetical protein Rv2085 {Mycobacterium tuberculosis H37Rv (lab strain)}
2081Rv2086hypothetical protein Rv2086 {Mycobacterium tuberculosis H37Rv (lab strain)}
2082Rv2087hypothetical protein Rv2087 {Mycobacterium tuberculosis H37Rv (lab strain)}
2083Rv2088, (MTCY49.28), len: 589. Probable pknJ, serine-threonine protein kinase, similar to serine/threonine-protein kinases eg PKWA_THECU P49695 putative serine/threonine-protein kinase (742 aa) FASTA scores, opt: 457, z-score: 392.1, E(): 2.7e-15, (26.0% identi (pknJ) {Mycobacterium tuberculosis H37Rv (lab strain)}
2084Rv2089c, (MTCY49.29c), len: 375. Probable pepQ, peptidase, similar to eg PEPQ_LACDL P46545, xaa-pro dipeptidase (368 aa), FASTA scores, opt: 617, z-score: 692.4, E(): 5.1e-32, (34.7% identity in 363 aa overlap); contains PS00491Aminopeptidase P and proline dipep (pepE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2085Rv2090hypothetical protein Rv2090 {Mycobacterium tuberculosis H37Rv (lab strain)}
2086Rv2091chypothetical protein Rv2091c {Mycobacterium tuberculosis H37Rv (lab strain)}
2087Rv2092c, (MTCY49.32c), len: 906. Probable helicase helY, similarity to YJF0_YEAST P47047 hypothetical helicasein tdh1-gyp6 intergenic region, (1073 aa), FASTA scores, opt: 1004 z-score: 1097.5 E(): 0, (29.0% identity in 970 aa overlap); contains PS00017 ATP/GTP- (helY) {Mycobacterium tuberculosis H37Rv (lab strain)}
2088Rv2093chypothetical protein Rv2093c {Mycobacterium tuberculosis H37Rv (lab strain)}
2089Rv2094chypothetical protein Rv2094c {Mycobacterium tuberculosis H37Rv (lab strain)}
2090Rv2095chypothetical protein Rv2095c {Mycobacterium tuberculosis H37Rv (lab strain)}
2091Rv2096chypothetical protein Rv2096c {Mycobacterium tuberculosis H37Rv (lab strain)}
2092Rv2097chypothetical protein Rv2097c {Mycobacterium tuberculosis H37Rv (lab strain)}
2093Rv2098cProtein sequence is in conflict with the conceptual translation; Rv2098c, (MTCY49.38c), len: 434. Member of M. tuberculosis PE-family, PGRS sub-family. Frameshifted near N-terminus (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2094Rv2099c, (MTCY49.39c), len: 58. 5-end of MTCY49.38c, then frameshifts. Sequence has been checked, no errors found (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2095Rv2100hypothetical protein Rv2100 {Mycobacterium tuberculosis H37Rv (lab strain)}
2096Rv2101, (MTV020.01), len: 1013. Probable, helZ, helicase similar to many e.g. Synechocystis sp. PCC6803 P74552. FASTA scores: sptr|P74552|P74552 HELICASE OF THE SNF2/RAD54 FAMILY. (1039 aa) opt: 2015 z-score: 2280.4 E(): 0; 38.4% identity in 1063 aa overlap. TB (helZ) {Mycobacterium tuberculosis H37Rv (lab strain)}
2097Rv2102hypothetical protein Rv2102 {Mycobacterium tuberculosis H37Rv (lab strain)}
2098Rv2103chypothetical protein Rv2103c {Mycobacterium tuberculosis H37Rv (lab strain)}
2099Rv2104chypothetical protein Rv2104c {Mycobacterium tuberculosis H37Rv (lab strain)}
2100Rv2105hypothetical protein Rv2105 {Mycobacterium tuberculosis H37Rv (lab strain)}
2101Rv2106hypothetical protein Rv2106 {Mycobacterium tuberculosis H37Rv (lab strain)}
2102Rv2107, (MTCY261.03), len: 105 aa. Member of PE family N-terminal eg. Y03A_MYCTU Q10637 hypothetical glycine-rich 49.6 kd protein (603 aa), fasta scores; opt: 214 z-score: 387.2 E(): 1.3e-14, 39.8% identity in 93 aa overlap (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2103Rv2108, (MTCY261.04), len: 243 aa; N-terminus is similar to N-terminal region of M. tuberculosis PPE family proteins eg. YX23_MYCTU Q10813 hypothetical 41.1 kd protein cy274.23 (404 aa), fasta scores; opt: 431 z-score: 701.6 E(): 3.9e-32, 44.0% identity in 166 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2104Rv2109c, (MTCY261.05c), len: 248 aa. Proteasome alpha-type subunit 1, highly similar to TR:Q53080 (EMBL:U26421) proteasome alpha-type subunit 1 from Rhodococcus (259 aa), fasta scores; opt: 1035 z-score: 1663.7 E(): 0, 67.2% identity in 247 aa overlap (prcA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2105Rv2110c, (MTCY261.06c), len: 291 aa. Proteasome beta-type subunit 2, highly similar to eg. TR:Q53083 (EMBL:U26422) proteasome beta-type subunit 2 from Rhodococcus (292 aa), fasta scores; opt: 1103 z-score: 1446.0 E(): 0, 64.5% identity in 262 aa overlap (prcB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2106Rv2111chypothetical protein Rv2111c {Mycobacterium tuberculosis H37Rv (lab strain)}
2107Rv2112chypothetical protein Rv2112c {Mycobacterium tuberculosis H37Rv (lab strain)}
2108Rv2113hypothetical protein Rv2113 {Mycobacterium tuberculosis H37Rv (lab strain)}
2109Rv2114hypothetical protein Rv2114 {Mycobacterium tuberculosis H37Rv (lab strain)}
2110Rv2115chypothetical protein Rv2115c {Mycobacterium tuberculosis H37Rv (lab strain)}
2111Rv2116, (MTCY261.12), len: 189 aa. lppK, Similar toM. leprae B2126_F3_115 TR:Q49803 (194 aa), fasta scores; opt: 624 z-score: 685.3 E(): 3.1e-31, 51.6% identity in 190 aa overlap. Contains N-terminal signal sequence and PS00013Prokaryotic membrane lipoprotein l (lppK) {Mycobacterium tuberculosis H37Rv (lab strain)}
2112Rv2117hypothetical protein Rv2117 {Mycobacterium tuberculosis H37Rv (lab strain)}
2113Rv2118chypothetical protein Rv2118c {Mycobacterium tuberculosis H37Rv (lab strain)}
2114Rv2119hypothetical protein Rv2119 {Mycobacterium tuberculosis H37Rv (lab strain)}
2115Rv2120chypothetical protein Rv2120c {Mycobacterium tuberculosis H37Rv (lab strain)}
2116Rv2121c, (MTCY261.17c), len: 284 aa. Probable hisG atp phosphoribosyltransferase, similar to eg. HIS1_ECOLI P10366 atp phosphoribosyltransferase (299 aa), fasta scores; opt: 351 z-score: 485.1 E(): 4.5e-20, 31.8% identity in 289aa overlap (hisG) {Mycobacterium tuberculosis H37Rv (lab strain)}
2117Rv2122c, (MTCY261.18), len: 93 aa. hisI, Probable phosphoribosyl-amp cyclohydrolase, similar to N-terminus of eg. HIS2_SYNY3 P74755 phosphoribosyl-amp cyclohydrolase (230 aa), fasta scores; opt: 150 z-score: 270.5 E(): 4e-08, 37.9% identity in 87 aa overlap (hisI) {Mycobacterium tuberculosis H37Rv (lab strain)}
2118Rv2123, (MTCY261.19), len: 473 aa. Member of the M.tuberculosis PPE family of proteins but the C-terminus is not Gly-, Ala, Asn-rich. (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2119Rv2124c, (MTCY261.20c), len: 1192 aa. Probable metH, methionine synthase, similar to many eg, METH_ECOLI P13009 5-methyltetrahydrofolate--homocystein methyltransferase (1226 aa), fasta scores; opt: 1446 z-score: 1393.5 E(): 0, 32.1% identity in 1223 aa overlap. (metH) {Mycobacterium tuberculosis H37Rv (lab strain)}
2120Rv2125hypothetical protein Rv2125 {Mycobacterium tuberculosis H37Rv (lab strain)}
2121Rv2126c, (MTCY261.22c), len: 256 aa. Possible PE_PGRS pseudogene fragment, similar to the Gly-rich C-terminus of many members of the M. tuberculosis PGRS family eg. MTCY441.04c (778 aa), fasta scores; opt: 935 z-score: 418.8 E(): 4.4e-18, 56.1% identity in 271 a (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2122Rv2127, (MTCY261.26), len: 489 aa. ansP, l-asparagine permease, highly similar to many eg. ANSP_ECOLI P77610 l-asparagine permease (l-asparagine transport protein) (516aa), fasta scores; opt: 1880 z-score: 2362.5 E(): 0, 60.3%identity in 463 aa overlap. Probabl (ansP) {Mycobacterium tuberculosis H37Rv (lab strain)}
2123Rv2128hypothetical protein Rv2128 {Mycobacterium tuberculosis H37Rv (lab strain)}
2124Rv2129chypothetical protein Rv2129c {Mycobacterium tuberculosis H37Rv (lab strain)}
2125Rv2130c, (MTCY261.29c), len: 414. Probable cysS2, cysteinyl-trna synthetase, similar to many eg. SYC_ECOLI P21888 cysteinyl-trna synthetase (461 aa), fasta scores; opt: 535 z-score: 857.2 E(): 0, 37.0% identity in 370 aa overlap. Also simialr to M. tuberculosis (cysS2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2126Rv2131c, (MTCY270.37), len: 267. cysQ, equivalent to M. leprae CYSQ_MYCLE P46726 cysq protein homolog. (289 aa). Contains inositol monophosphatase family signature 1 (PS00629), significance uncertain. FASTA best: CYSQ_MYCLE P46726 cysq protein homolog. (289 aa) (cysQ) {Mycobacterium tuberculosis H37Rv (lab strain)}
2127Rv2132hypothetical protein Rv2132 {Mycobacterium tuberculosis H37Rv (lab strain)}
2128Rv2133chypothetical protein Rv2133c {Mycobacterium tuberculosis H37Rv (lab strain)}
2129Rv2134chypothetical protein Rv2134c {Mycobacterium tuberculosis H37Rv (lab strain)}
2130Rv2135chypothetical protein Rv2135c {Mycobacterium tuberculosis H37Rv (lab strain)}
2131Rv2136chypothetical protein Rv2136c {Mycobacterium tuberculosis H37Rv (lab strain)}
2132Rv2137chypothetical protein Rv2137c {Mycobacterium tuberculosis H37Rv (lab strain)}
2133Rv2138, (MTCY270.30c), len: 358. Function: unknown possible lipoprotein with appropriately placed lipoprotein signature (PS00013) strongly similar to hypothetical M. leprae protein, Q49806. FASTA best: Q49806 B2126_F3_142. (298 aa) opt: 1495 z-score: 1474.0 E() (lppL) {Mycobacterium tuberculosis H37Rv (lab strain)}
2134Rv2139, (MTCY270.29c), len: 357. Function pyrD: probable dihydroorotate dehydrogenase (EC 1.3.3.1) contains dihydroorotate dehydrogenase signatures 1 and 2 (PS00911, PS00912). FASTA best: PYRD_MYCLE P46727 dihydroorotate dehydrogenase(309 aa) opt: 1653 z-score: (pyrD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2135Rv2140chypothetical protein Rv2140c {Mycobacterium tuberculosis H37Rv (lab strain)}
2136Rv2141c, (MTCY270.27), len: 448. dapE, ut shows some similarity to acetylornithine deacetylase and succinyl-diaminopimelate desuccinylase and cotains ArgE/dapE/ACY1/CPG2/yscS family signature 1 (PS00758). FASTA best: CBPS_YEASTP27614 carboxypeptidase s precursor (dapE2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2137Rv2142chypothetical protein Rv2142c {Mycobacterium tuberculosis H37Rv (lab strain)}
2138Rv2143hypothetical protein Rv2143 {Mycobacterium tuberculosis H37Rv (lab strain)}
2139Rv2144chypothetical protein Rv2144c {Mycobacterium tuberculosis H37Rv (lab strain)}
2140Rv2145c, (MTCY270.23), len:260. Function: unknown but corresponds to antigen 84 of M. tuberculosis (wag31). Predicted to contain significant amount of coiled coil structure. FASTA best: AG84_MYCTU P46816 antigen 84 (wag31) {Mycobacterium tuberculosis H37Rv (lab strain)}
2141Rv2146chypothetical protein Rv2146c {Mycobacterium tuberculosis H37Rv (lab strain)}
2142Rv2147chypothetical protein Rv2147c {Mycobacterium tuberculosis H37Rv (lab strain)}
2143Rv2148chypothetical protein Rv2148c {Mycobacterium tuberculosis H37Rv (lab strain)}
2144Rv2149c, (MTCY270.19), len: 250. Function yfiH: unknown but corresponds to hypothetical 25.3 kDa YfiH protein in ftsZ 3 region of Streptomyces griseus, and to YfiH proteins in other bacteria. FASTA best: YFIH_STRGR P45496, (246aa) opt: 722 z-score: 797.9 E(): 1. (yfiH) {Mycobacterium tuberculosis H37Rv (lab strain)}
2145Rv2150c, (MTCY270.18), len: 379. Function ftsZ: Probable cell division protein FtsZ, contains FtsZ protein signature 2 (PS01135). FASTA best: FTSZ_STRCO P45500 cell division protein FtsZ (399 aa) opt: 1674 z-score: 1782.0 E(): 0; (77.3% identity in 339 aa overla (ftsZ) {Mycobacterium tuberculosis H37Rv (lab strain)}
2146Rv2151c, (MTCY270.17), len: 314. Function ftsQ: possible cell division protein, some homology to FTSQ_STRGR P45503 cell division protein ftsq homolog (208 aa), fasta scores; opt: 204 z-score: 217.5 E(): 4e-05; (30.6% identity in193 aa overlap) (ftsQ) {Mycobacterium tuberculosis H37Rv (lab strain)}
2147Rv2152c, (MTCY270.16), len: 494. Function murC: probable UDP-N-acetylmuramate-alanine ligase (EC 6.3.2.8). FASTA best: MURC_ECOLI P17952 (491 aa) opt: 764 z-score: 861.0E(): 0; (36.9% identity in 474 aa overlap) (murC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2148Rv2153c, (MTCY270.15), len: 410. Function: probableMURG PROTEIN (UPD-N-acetylglucosamine-N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol-N-acetylglucosamine transferase. FASTA best: MURG_BACSU P37585 murg protein (363aa) opt: 494 z-score: 497.2 E(): 1 (murG) {Mycobacterium tuberculosis H37Rv (lab strain)}
2149Rv2154c, (MTCY270.14), len: 524. ftsW, probable cell division protein FtsW, related to MTCY10H4.17c, 3.2e-17. FASTA best: SP5E_BACSU P07373 stage v sporulation protein e(366 aa) opt: 755 z-score: 727.2 E(): 1.6e-33; (38.4% identity in 357 aa overlap) (ftsW) {Mycobacterium tuberculosis H37Rv (lab strain)}
2150Rv2155c, (MTCY270.13), len: 486. Function: probableUDP-N-acetylmuramoylalanine-D-glutamate ligase (EC 6.3.2.9). FASTA best: MURD_BACSU Q03522 (451 aa) opt: 534 z-score:579.8 E(): 2.7e-25; (28.8% identity in 483 aa overlap); containsPS01011 Folylpolyglutamate syn (murD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2151Rv2156c, (MTCY270.12), len: 359. Function: probable phospho-N-acetylmuramoyl- pentappeptidetransferase (EC 2.7.8.13). FASTA best: MRAY_ECOLI P15876 (360 aa) opt: 572 z-score: 651.6 E(): 2.7e-29; (35.8% identity in 344 aa overlap) (murX) {Mycobacterium tuberculosis H37Rv (lab strain)}
2152Rv2157c, (MTCY270.11), len: 510. Function: probable UDP-N-acetylmuramoylalanyl-D-glutamyl- 2,6-diaminopimelate-D-alanyl-D-alanyl ligase (EC 6.3.2.15) (UDP-MURNAC-PENTAPEPTIDE SYNTHETASE) also related to other M. tuberculosis mur gene products. FASTA best: MURF_E (murF) {Mycobacterium tuberculosis H37Rv (lab strain)}
2153Rv2158c, (MTCY270.10), len: 535. Function murE: probable UDP-N-acetylmuramoylalanyl-D- glutamate-2,6-diaminopimelate ligase (EC 6.3.2.13; UDP-N-ACETYLMURAMYL-TRIPEPTIDE SYNTHETASE) also related to other M. tuberculosis mur gene products. FASTA best: MURE_BACSU Q (murE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2154Rv2159chypothetical protein Rv2159c {Mycobacterium tuberculosis H37Rv (lab strain)}
2155Rv2160chypothetical protein Rv2160c {Mycobacterium tuberculosis H37Rv (lab strain)}
2156Rv2161chypothetical protein Rv2161c {Mycobacterium tuberculosis H37Rv (lab strain)}
2157Rv2162c, (MTCY270.06), len: 532. Function: member of PE family, PGRS subfamily includes (best matches) MTCY21B4.13c, 0; cY130.seq 0; MTCY1A11.25c, 0; MTC1A11.04, 0; MTCY359.33, 0; MTCY227.10c, 0; MTCY06H11.16c, 0; MTCY253.25c, 0; MTCY441.04c, 0; MTCY49.39c, 0; M (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2158Rv2163c, (MTCY270.05), len: 679. Function pbpB: probable penicillin-binding protein, similar to many bacterialPBP2s and to MTCY10H4.16c; 2.8e-10. Contains possible ATP/GTP-binding site motif A (P-loop; PS00017) near C-terminus.FASTA best: PBP2_NEIME P11882 penic (pbpB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2159Rv2164chypothetical protein Rv2164c {Mycobacterium tuberculosis H37Rv (lab strain)}
2160Rv2165chypothetical protein Rv2165c {Mycobacterium tuberculosis H37Rv (lab strain)}
2161Rv2166chypothetical protein Rv2166c {Mycobacterium tuberculosis H37Rv (lab strain)}
2162Rv2167chypothetical protein Rv2167c {Mycobacterium tuberculosis H37Rv (lab strain)}
2163Rv2168chypothetical protein Rv2168c {Mycobacterium tuberculosis H37Rv (lab strain)}
2164Rv2169chypothetical protein Rv2169c {Mycobacterium tuberculosis H37Rv (lab strain)}
2165Rv2170hypothetical protein Rv2170 {Mycobacterium tuberculosis H37Rv (lab strain)}
2166Rv2171, (MTV021.04), len: 227. Probable lipoproteincontainsputative signal peptide and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachmentsite. Has hydrophobic stretch at C-terminus and also contains PS00225 Crystallins beta and g (lppM) {Mycobacterium tuberculosis H37Rv (lab strain)}
2167Rv2172chypothetical protein Rv2172c {Mycobacterium tuberculosis H37Rv (lab strain)}
2168Rv2173, (MTV021.06), len: 352. Probable, idsA2, geranylgeranyl pyrophosphate synthase similar to many e.g. Streptomyces griseus geranylgeranyl pyrophosphate synthase Q54193 (425 aa). Contains PS00723 and PS00444Polyprenyl synthetases signature 1and 2. FASTA sco (idsA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2169Rv2174hypothetical protein Rv2174 {Mycobacterium tuberculosis H37Rv (lab strain)}
2170Rv2175chypothetical protein Rv2175c {Mycobacterium tuberculosis H37Rv (lab strain)}
2171Rv2176, (MTV021.09), len: 399. Probable serine-threonine protein kinase, pknL, similar to many e.g. MLCB1770_9(622 aa). LacksC-terminal domain and ends with putative transmembrane segment. Contains PS00108 Serine/Threonine protein kinases active-site signature. (pknL) {Mycobacterium tuberculosis H37Rv (lab strain)}
2172Rv2177chypothetical protein Rv2177c {Mycobacterium tuberculosis H37Rv (lab strain)}
2173Rv2178c, (MTV021.11c), len: 462. Probable aroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase similar to many, especially those from plants. FASTA scores: Y15113|MC3DDAH7P_1Morinda citrifolia mRNA for 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase ( (aroG) {Mycobacterium tuberculosis H37Rv (lab strain)}
2174Rv2179chypothetical protein Rv2179c {Mycobacterium tuberculosis H37Rv (lab strain)}
2175Rv2180chypothetical protein Rv2180c {Mycobacterium tuberculosis H37Rv (lab strain)}
2176Rv2181hypothetical protein Rv2181 {Mycobacterium tuberculosis H37Rv (lab strain)}
2177Rv2182chypothetical protein Rv2182c {Mycobacterium tuberculosis H37Rv (lab strain)}
2178Rv2183chypothetical protein Rv2183c {Mycobacterium tuberculosis H37Rv (lab strain)}
2179Rv2184chypothetical protein Rv2184c {Mycobacterium tuberculosis H37Rv (lab strain)}
2180Rv2185chypothetical protein Rv2185c {Mycobacterium tuberculosis H37Rv (lab strain)}
2181Rv2186chypothetical protein Rv2186c {Mycobacterium tuberculosis H37Rv (lab strain)}
2182Rv2187, (MTV021.20), len: 600. Probable fadD15, long-chain-fatty-acid-CoA ligase, similar to several best withP44446|LCFH_HAEIN (607 aa). Contains PS00455 Putative AMP-binding domain signature. FASTA scores: sp|P44446|LCFH_HAEINPUTATIVE LONG-CHAIN-FATTY-ACID--C (fadD15) {Mycobacterium tuberculosis H37Rv (lab strain)}
2183Rv2188chypothetical protein Rv2188c {Mycobacterium tuberculosis H37Rv (lab strain)}
2184Rv2189chypothetical protein Rv2189c {Mycobacterium tuberculosis H37Rv (lab strain)}
2185Rv2190chypothetical protein Rv2190c {Mycobacterium tuberculosis H37Rv (lab strain)}
2186Rv2191hypothetical protein Rv2191 {Mycobacterium tuberculosis H37Rv (lab strain)}
2187Rv2192c, (MTCY190.03c), len: 370. Probable anthranilate phosphoribosyltransferase, TRPD, similar to eg SW:TRPD_LACCA P17170, (43.2% identity in 308 aa overlap), initiatiation codon uncertain, gtg at 4086 favoured by homology butthis has no clear ribosome binding (trpD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2188Rv2193, (MTCY190.04), len: 203. Probable ,ctaE, strong similarity to cytochrome c oxidase polypeptide III (cox3) eg SW:COX3_SYNY3 Q06475 (29.8% identity in 225 aa overlap) (ctaE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2189Rv2194, (MTCY190.05), len: 280. Probable cyoA, shows similarity to cytochrome c family; contains 2 X PS00190 Cytochrome c family heme-binding site signature (qcrC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2190Rv2195, (MTCY190.06), len: 429. Probable cyoB, shows some similarity to cytochrome B6-F complex iron-sulphur subunits (Rieske iron-sulfur protein); contains PS00200 Rieske iron-sulfur protein signature 2 (qcrA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2191Rv2196, (MTCY190.07), len: 549. Probable cytB, integral membrane protein, low similarity in amino-terminal half to cytochrome b subunits, highly similar at C-terminus toSW:12KD_MYCLE P15878 12 KD protein PIR:S08427 (86.9% identity in 153 aa overlap). FASTA scor (qcrB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2192Rv2197chypothetical protein Rv2197c {Mycobacterium tuberculosis H37Rv (lab strain)}
2193Rv2198c, (MTCY190.09c), len: 301. Unknown, containsPS00499 C2 domain signature, contains a hydrophobic region,contains a repetitive proline and threonine rich region (mmpS3) {Mycobacterium tuberculosis H37Rv (lab strain)}
2194Rv2199chypothetical protein Rv2199c {Mycobacterium tuberculosis H37Rv (lab strain)}
2195Rv2200c, (MTCY190.11c), len: 363. ctaC, COX2, similar eg to PIR:JT0964 cytochrome-c oxidase chain II (23.0% identity in 317 aa overlap); contains PS00078 Cytochrome c oxidase subunit II, copper A binding region signature (ctaC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2196Rv2201, (MTCY190.12), len: 652. asnB, Probable asparagine synthetase, similar to eg SW:ASNH_BACSU P42113 putative asparagine synthetase (26.0% identity in 438 aa overlap) (asnB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2197Rv2202c, (MTCY190.13c), len: 324.cbhK, Probable carbohydrate kinase (but not ribose), similar to several e.g.AE000915_1 Methanobacterium thermoautotrop (309 aa) FASTA score: opt: 370 z-score: 462.1 E(): 3.3e-18; 31.2% identity in 276 aa overlap. Low similarity t (cbhK) {Mycobacterium tuberculosis H37Rv (lab strain)}
2198Rv2203hypothetical protein Rv2203 {Mycobacterium tuberculosis H37Rv (lab strain)}
2199Rv2204chypothetical protein Rv2204c {Mycobacterium tuberculosis H37Rv (lab strain)}
2200Rv2205chypothetical protein Rv2205c {Mycobacterium tuberculosis H37Rv (lab strain)}
2201Rv2206hypothetical protein Rv2206 {Mycobacterium tuberculosis H37Rv (lab strain)}
2202Rv2207, (MTCY190.18), len: 361.cobT, Probable phosphoribosyltransferase (cobT), similar to many eg SW:COBT_ECOLI P36562 nicotinate-nucleotide--dimethylbenzimidazol phosphoribosyltransferase (34.6% identity in 341 aa overlap) (cobT) {Mycobacterium tuberculosis H37Rv (lab strain)}
2203Rv2208, (MTCY190.19), len: 249. Probable CobS, similarity to SW:COBS_ECOLI P36561 cobalamin (5-phosphate) synthase (28.0% identity in 243 aa overlap) (cobS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2204Rv2209hypothetical protein Rv2209 {Mycobacterium tuberculosis H37Rv (lab strain)}
2205Rv2210c, (MTCY190.21c), len: 368.ilvE, Branched-chain-amino-acid transaminase, similar to many e.g. SW:YWAA_BACSU P39576 hypothetical 40.3 KD protein (48.4% identity in339 aa overlap) (ilvE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2206Rv2211c, (MTCY190.22), len: 379. gcvT, Aminomethyltransferase (GCVT), similar to many eg SW:GCST_ECOLI P27248 (38.2% identity in 364 aa overlap) (gcvT) {Mycobacterium tuberculosis H37Rv (lab strain)}
2207Rv2212hypothetical protein Rv2212 {Mycobacterium tuberculosis H37Rv (lab strain)}
2208Rv2213, (MTCY190.24), len: 515. Probable pepA, verysimilar to aminopeptidases eg SW:AMPA_ECOLI P11648 aminopeptidase A/I, (41.4% identity in 309 aa overlap); Equivalentto Z98741|MLCB22_6 Mycobacterium leprae cosmid B22; Am (524 aa) FASTA scores: opt: 2793 z-sco (pepB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2209Rv2214c, (MTCY190.25c), len: 592.ephD, Equivalent to Z98741|MLCB22_8 Mycobacterium leprae cosmid B22; Ox (596aa)FASTA score: opt: 3262 z-score: 3601.1 E(): 0Smith-Waterman score: 3262; 80.4% identity in 596 aa overlap.C-terminus similar to short-chain alcohol de (ephD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2210Rv2215, (MTCY190.26), len: 553. Probable dihydrolipoamide acetyltransferase component (E2), similar to eg SW:OPD2_ACHLA P35489 dihydrolipoamide acetyltransferase component (E2) of pyruvate dehydrogenase complex (35.3% identity in 552 aa overlap); contains PS001 (sucB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2211Rv2216hypothetical protein Rv2216 {Mycobacterium tuberculosis H37Rv (lab strain)}
2212Rv2217, (MTCY190.28), len: 230. Probable lipB, similar to SW:LIPB_ECOLI P30976 liopate biosynthesis protein B (33.8% identity in 160 aa overlap). Equivalent to gp|Z98741|MLCB22_11 Mycobacterium leprae (235 aa). FASTA score: opt:1124 z-score: 1394.6 E(): 0; 78.4 (lipB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2213Rv2218, (MTCY190.29), len: 311. Probable lipoic acid synthetase (lipA), similar to eg SW:LIPA_HAEIN P44463 (42.6% identity in 291 aa overlap). Equivalent to Z98741|MLCB22_12 Mycobacterium leprae cosmid B22; L (314 aa)FASTA score: opt: 1836 z-score: 2219.0 E(): (lipA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2214Rv2219hypothetical protein Rv2219 {Mycobacterium tuberculosis H37Rv (lab strain)}
2215Rv2220, (MTCY190.31-MTCY427.01), len: 478.glnA1, Probable glutamine synthetase, glnA, similar to many eg SW:GLNA_STRCO P15106 (71.4% identity in 475 aa overlap); contains PS00180 Glutamine synthetase signature 1, PS00181 Glutamine synthetase putative ATP-bindin (glnA1) {Mycobacterium tuberculosis H37Rv (lab strain)}
2216Rv2221c, (MTCY190.32c-MTCY427.02c), len: 994. glnE,Probable glnE, similar to SW:GLNE_ECOLI P30870 glutamate-ammonia-ligase adenylyltransferase (24.4% identity in 721 aaoverlap) and SW:GLNE_HAEIN P44419 (28.1% identity in 199 aa overlap); initiation codon uncerta (glnE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2217Rv2222c, (MTCY427.03c), len: 446. glnA2, probable gln2, (overlaps MTCY190.33c partial sequence) probable classII glutamine synthetase, similar to MTCY190.31 (and partialorf MTCY427.01) (34.3% identity in 300 aa overlap) (glnA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2218Rv2223chypothetical protein Rv2223c {Mycobacterium tuberculosis H37Rv (lab strain)}
2219Rv2224chypothetical protein Rv2224c {Mycobacterium tuberculosis H37Rv (lab strain)}
2220Rv2225, (MTCY427.06), len: 281. panB, similar to SW:PANB_ECOLI P31057 3-methyl-2-oxobutanoate hydroxymethyltransferase (45.9% identity in 257 aa overlap) (panB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2221Rv2226hypothetical protein Rv2226 {Mycobacterium tuberculosis H37Rv (lab strain)}
2222Rv2227hypothetical protein Rv2227 {Mycobacterium tuberculosis H37Rv (lab strain)}
2223Rv2228chypothetical protein Rv2228c {Mycobacterium tuberculosis H37Rv (lab strain)}
2224Rv2229chypothetical protein Rv2229c {Mycobacterium tuberculosis H37Rv (lab strain)}
2225Rv2230chypothetical protein Rv2230c {Mycobacterium tuberculosis H37Rv (lab strain)}
2226Rv2231c, (MTCY427.12c), len: 364. Probable cobC, initiation codon uncertain, similar to CobC aminotransferases e.g sp|P21633|COBC_PSEDE COBC PROTEIN (333 aa) opt: 277 z-score: 341.5 E(): 1.7e-11; 28.8% identity in 313 aa overlap and also to eg SW:HIS8_ECOLI P069 (cobC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2227Rv2232hypothetical protein Rv2232 {Mycobacterium tuberculosis H37Rv (lab strain)}
2228Rv2233hypothetical protein Rv2233 {Mycobacterium tuberculosis H37Rv (lab strain)}
2229Rv2234, (MTCY427.15), len: 163. ptpA, probable low molecular weight protein-tyrosine-phosphatase, similar to phosphotyrosine protein phosphatases eg P53433|PTPA_STRCO LOW MOLECULAR WEIGHT PROTEIN-TYR (164 aa) opt: 455; E(): 3.3e-25; 49.7% identity in 155 aa ove (ptpA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2230Rv2235hypothetical protein Rv2235 {Mycobacterium tuberculosis H37Rv (lab strain)}
2231Rv2236c, (MTCY427.17c), len: 313 Probable cobD, membrane protein similar to PIR:S52223 Rhodobacter capsulatus 945 protein BluD (39.0% identity in 287 aa overlap) involved in cobinamide synthesis, and to SW:COBD_PSEDE Pseudomonasdentrificans cobD protein (37.5% i (cobD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2232Rv2237hypothetical protein Rv2237 {Mycobacterium tuberculosis H37Rv (lab strain)}
2233Rv2238c, (MTCY427.19c), len: 153. ahpE. Similarity to many members of AHPC/TSA family e.g. sp|Q96291|BAS1_ARATH 2-CYS PEROXIREDOXIN BAS1 PRECURSOR (265 aa). FASTA score:opt: 275 z-score: 356.0 E(): 2.7e-12; 35.0% identity in143 aa overlap (ahpE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2234Rv2239chypothetical protein Rv2239c {Mycobacterium tuberculosis H37Rv (lab strain)}
2235Rv2240chypothetical protein Rv2240c {Mycobacterium tuberculosis H37Rv (lab strain)}
2236Rv2241, (MTCY427.22), len: 901. aceE, pyruvate dehydrogenase E1 component, similar to SW:ODP1_ECOLI P06958 pyruvate dehydrogenase E1 component (51.2% identity in 891 aa overlap) (aceE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2237Rv2242hypothetical protein Rv2242 {Mycobacterium tuberculosis H37Rv (lab strain)}
2238Rv2243, (MTCY427.24), len: 302. fabD, highly similar to A57356 - acyl-CoA carrier protein malonyltransferase from Streptomyces coelicolor. FASTA score: A57356 (316 aa) opt: 955 E(): 0 (52.6% identity in 304 aa overlap) and SW:FABD_HAEIN P43712 malonyl CoA-acyl (fabD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2239Rv2244, (MTCY427.25), len: 115. acpM, acyl carrier protein involved in meromycolate extension. Highly similar to acyl carrier protein from Streptomyces glaucescens. eg L43074|STMFABD2 STMFABD NID: g870805 - (82 aa) opt: 298 E(): 8.4e-13; (56.6% identity in 76 a (acpM) {Mycobacterium tuberculosis H37Rv (lab strain)}
2240Rv2245, (MTCY427.26), len: 416, kasA, beta-ketoacyl-ACP synthase, involved in meromycolate extension. Highly similar to beta-ketoacyl-ACP synthase from Streptomyces glaucescens FASTA score: L43074|STMFABD3 STMFABD NID: g870805 -Streptomyce (423 aa)opt: 1105; E( (kasA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2241Rv2246, (MTCY427.27), len: 438. kasB, beta-ketoacyl-ACP synthase, involved in meromycolate extension. Very similar to L43074|STMFABD3 STMFABD NID: g870805 - (423 aa) opt: 1091 E(): 0; (44.7% identity in 416 aa overlap), also similar to SW:FABF_ECOLI P39435 3-ox (kasB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2242Rv2247, (MTCY427.28), len: 520, accD6 - Acetyl/Propionyl CoA Carboxylase beta subunit, highly similar to SW:PCCB_RHOSO Q06101 propionyl-CoA carboxylase beta chain (75.1%identity in 437 aa overlap). Similar to many other M. tuberculosis Acetyl/Propionyl CoA Carb (accD6) {Mycobacterium tuberculosis H37Rv (lab strain)}
2243Rv2248hypothetical protein Rv2248 {Mycobacterium tuberculosis H37Rv (lab strain)}
2244Rv2249c, (MTCY427.31c), len: 516. glpD1, glycerol-3-phosphate dehydrogenase, similar to SW:GLPD_ECOLI P13035 aerobic glycerol-3-phosphate dehydrogenase (30.0% identity in 486 aa overlap) and SW:GLPA_ECOLI P13032 anaerobic glycerol-3-phosphate dehydrogenase (28.2 (glpD1) {Mycobacterium tuberculosis H37Rv (lab strain)}
2245Rv2250chypothetical protein Rv2250c {Mycobacterium tuberculosis H37Rv (lab strain)}
2246Rv2251hypothetical protein Rv2251 {Mycobacterium tuberculosis H37Rv (lab strain)}
2247Rv2252hypothetical protein Rv2252 {Mycobacterium tuberculosis H37Rv (lab strain)}
2248Rv2253hypothetical protein Rv2253 {Mycobacterium tuberculosis H37Rv (lab strain)}
2249Rv2254chypothetical protein Rv2254c {Mycobacterium tuberculosis H37Rv (lab strain)}
2250Rv2255chypothetical protein Rv2255c {Mycobacterium tuberculosis H37Rv (lab strain)}
2251Rv2256chypothetical protein Rv2256c {Mycobacterium tuberculosis H37Rv (lab strain)}
2252Rv2257chypothetical protein Rv2257c {Mycobacterium tuberculosis H37Rv (lab strain)}
2253Rv2258chypothetical protein Rv2258c {Mycobacterium tuberculosis H37Rv (lab strain)}
2254Rv2259, (MTV022.09), len: 361; adhE2 - similar to several alcohol dehydrogenases like MTCI28.02c. Contains PS00059 Zinc-containing alcohol dehydrogenases signature. FASTAscores: sptr|O07407|O07407 ALCOHOL DEHYDROGENASE.(383 aa) opt: 720 z-score: 833.8 E(): 0; ( (adhE2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2255Rv2260hypothetical protein Rv2260 {Mycobacterium tuberculosis H37Rv (lab strain)}
2256Rv2261chypothetical protein Rv2261c {Mycobacterium tuberculosis H37Rv (lab strain)}
2257Rv2262chypothetical protein Rv2262c {Mycobacterium tuberculosis H37Rv (lab strain)}
2258Rv2263hypothetical protein Rv2263 {Mycobacterium tuberculosis H37Rv (lab strain)}
2259Rv2264chypothetical protein Rv2264c {Mycobacterium tuberculosis H37Rv (lab strain)}
2260Rv2265hypothetical protein Rv2265 {Mycobacterium tuberculosis H37Rv (lab strain)}
2261Rv2266hypothetical protein Rv2266 {Mycobacterium tuberculosis H37Rv (lab strain)}
2262Rv2267chypothetical protein Rv2267c {Mycobacterium tuberculosis H37Rv (lab strain)}
2263Rv2268chypothetical protein Rv2268c {Mycobacterium tuberculosis H37Rv (lab strain)}
2264Rv2269chypothetical protein Rv2269c {Mycobacterium tuberculosis H37Rv (lab strain)}
2265Rv2270, (MTCY339.40c), len: 175. Probable lipoprotein, has appropriately positioned prokaryotic membrane lipoprotein attachment site PS00013 (lppN) {Mycobacterium tuberculosis H37Rv (lab strain)}
2266Rv2271hypothetical protein Rv2271 {Mycobacterium tuberculosis H37Rv (lab strain)}
2267Rv2272hypothetical protein Rv2272 {Mycobacterium tuberculosis H37Rv (lab strain)}
2268Rv2273hypothetical protein Rv2273 {Mycobacterium tuberculosis H37Rv (lab strain)}
2269Rv2274chypothetical protein Rv2274c {Mycobacterium tuberculosis H37Rv (lab strain)}
2270Rv2275hypothetical protein Rv2275 {Mycobacterium tuberculosis H37Rv (lab strain)}
2271Rv2276hypothetical protein Rv2276 {Mycobacterium tuberculosis H37Rv (lab strain)}
2272Rv2277chypothetical protein Rv2277c {Mycobacterium tuberculosis H37Rv (lab strain)}
2273Rv2278hypothetical protein Rv2278 {Mycobacterium tuberculosis H37Rv (lab strain)}
2274Rv2279hypothetical protein Rv2279 {Mycobacterium tuberculosis H37Rv (lab strain)}
2275Rv2280hypothetical protein Rv2280 {Mycobacterium tuberculosis H37Rv (lab strain)}
2276Rv2281, (MTCY339.29c), len: 552. Putative phosphatepermease, similar to YG04_HAEIN P45268 putative phosphate permease hi1604 (420 aa) FASTA scores, opt: 484, z-score: 538.1, E(): 5e-23, (33.5% identity in 498 aa overlap) also toG399598 amphotropic murine retrov (pitB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2277Rv2282chypothetical protein Rv2282c {Mycobacterium tuberculosis H37Rv (lab strain)}
2278Rv2283hypothetical protein Rv2283 {Mycobacterium tuberculosis H37Rv (lab strain)}
2279Rv2284, (MTCY339.26c), len: 431. Probable esterase similar to others e.g. gp|Z95844|MTCY493_28 Mycobacterium tuberculosis cosmid (420 aa) opt: 1266 z-score: 1430.8 E(): 0; 50.1% identity in 411 aa overlap. Some similarity to G537514 arylacetamide deacetylase (3 (lipM) {Mycobacterium tuberculosis H37Rv (lab strain)}
2280Rv2285hypothetical protein Rv2285 {Mycobacterium tuberculosis H37Rv (lab strain)}
2281Rv2286chypothetical protein Rv2286c {Mycobacterium tuberculosis H37Rv (lab strain)}
2282Rv2287, (MTCY339.23c), len: 542: Probable integral membrane protein, similar to eukaryote NA+/H+ echangers, most similar to YJCE_ECOLI P32703 hypothetical 60.5 kd protein in soxr- (549 aa) FASTA scores, opt: 436, z-score: 501.3,E(): 5.6e-21, (29.4% identity in (yjcE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2283Rv2288hypothetical protein Rv2288 {Mycobacterium tuberculosis H37Rv (lab strain)}
2284Rv2289, (MTCY339.21c), len: 260. cdh, similar to CDH_SALTY P26219 cdp-diacylglycerol pyrophosphatase (251 aa) FASTA scores, opt: 395, z-score: 482.9, E(): 5.9e-20, (33.5% identity in 221 aa overlap) (cdh) {Mycobacterium tuberculosis H37Rv (lab strain)}
2285Rv2290, (MTCY339.20c), len: 171. Possible lipoprotein similar to 19KD_MYCTU P11572 19 kd lipoprotein antigen precursor (159 aa) FASTA scores, opt: 119, z-score: 135.9, E(): 1.3, (25.6% identity in 164 aa overlap). Contains appropriately positioned PS00013 lipop (lppO) {Mycobacterium tuberculosis H37Rv (lab strain)}
2286Rv2291, (MTCY339.19c), len: 284. sseB, probable thiosulfate sulfurtransferase. Very similar to thiosulfate sulfurtransferas/rhodanese from Streptomyces coelicolor AL009204|SC9B10_21 (283 aa)initn: 762 init1: 394 opt: 765 z-score: 903.5 E(): 0Smith-Waterman scor (sseB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2287Rv2292chypothetical protein Rv2292c {Mycobacterium tuberculosis H37Rv (lab strain)}
2288Rv2293chypothetical protein Rv2293c {Mycobacterium tuberculosis H37Rv (lab strain)}
2289Rv2294hypothetical protein Rv2294 {Mycobacterium tuberculosis H37Rv (lab strain)}
2290Rv2295hypothetical protein Rv2295 {Mycobacterium tuberculosis H37Rv (lab strain)}
2291Rv2296hypothetical protein Rv2296 {Mycobacterium tuberculosis H37Rv (lab strain)}
2292Rv2297hypothetical protein Rv2297 {Mycobacterium tuberculosis H37Rv (lab strain)}
2293Rv2298hypothetical protein Rv2298 {Mycobacterium tuberculosis H37Rv (lab strain)}
2294Rv2299c, (MTCY339.11), len: 647. htpG ,HEAT SHOCK PROTEIN HSP90 FAMILY. similar to HTPG_BACSU P46208 heat shock protein htpg homologue (626 aa), FASTA scores, opt: 1551, z-score: 1717.7, E(): 0, (39.6% identity in 631 aa overlap). Contains eventual helix-turn-he (htpG) {Mycobacterium tuberculosis H37Rv (lab strain)}
2295Rv2300chypothetical protein Rv2300c {Mycobacterium tuberculosis H37Rv (lab strain)}
2296Rv2301hypothetical protein Rv2301 {Mycobacterium tuberculosis H37Rv (lab strain)}
2297Rv2302hypothetical protein Rv2302 {Mycobacterium tuberculosis H37Rv (lab strain)}
2298Rv2303chypothetical protein Rv2303c {Mycobacterium tuberculosis H37Rv (lab strain)}
2299Rv2304chypothetical protein Rv2304c {Mycobacterium tuberculosis H37Rv (lab strain)}
2300Rv2305hypothetical protein Rv2305 {Mycobacterium tuberculosis H37Rv (lab strain)}
2301Rv2306chypothetical protein Rv2306c {Mycobacterium tuberculosis H37Rv (lab strain)}
2302Rv2307chypothetical protein Rv2307c {Mycobacterium tuberculosis H37Rv (lab strain)}
2303Rv2308hypothetical protein Rv2308 {Mycobacterium tuberculosis H37Rv (lab strain)}
2304Rv2309chypothetical protein Rv2309c {Mycobacterium tuberculosis H37Rv (lab strain)}
2305Rv2310hypothetical protein Rv2310 {Mycobacterium tuberculosis H37Rv (lab strain)}
2306Rv2311hypothetical protein Rv2311 {Mycobacterium tuberculosis H37Rv (lab strain)}
2307Rv2312hypothetical protein Rv2312 {Mycobacterium tuberculosis H37Rv (lab strain)}
2308Rv2313chypothetical protein Rv2313c {Mycobacterium tuberculosis H37Rv (lab strain)}
2309Rv2314chypothetical protein Rv2314c {Mycobacterium tuberculosis H37Rv (lab strain)}
2310Rv2315chypothetical protein Rv2315c {Mycobacterium tuberculosis H37Rv (lab strain)}
2311Rv2316, (MTCY3G12.18c), len: 290. uspA, membrane protein probably involved in sugar transport, most similar toUGPA_ECOLI P10905 sn-glycerol-3-phosphate transport sys (295 aa), fasta scores, opt: 521, E(): 3.8e-27, (32.4% identity in 287 aa overlap) (uspA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2312Rv2317, (MTC3G12.17c), len: 274. uspB, membrane protein probably involved in sugar transport, most similar to G296356 putative transport system permease protein (275 aa)fasta scores, opt: 562, E(): 3.8e-32, (33.8% identity in 275 aa overlap) (uspE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2313Rv2318, (MTCY3G12.16c), len: 440. uspC, probably component of sugar transport system, has hydrophobic stretch possibly signal peptide at N-terminus. Similar to AF012836|AF012836_1 Thermococcus litoralis trehalos (450 aa) opt: 202 z-score: 238.9 E(): 8.8e-06; 24 (uspC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2314Rv2319chypothetical protein Rv2319c {Mycobacterium tuberculosis H37Rv (lab strain)}
2315Rv2320c, (MTCY3G12.14), len: 476. rocE, prob Arg, ornithine transporter, most similar to Z99108|BSUB0005_3 Bacillus subtilis (461 aa) opt: 1271 z-score: 1516.3 E(): 0;41.9% identity in 463 aa overlap; and G403170 ETHANOLAMINEPERMEASE (488 aa), fasta scores, opt: (rocE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2316Rv2321c, (MTCY3G12.13), len: 181. Probable rocD, similar to C-terminal region of OAT_BACSU P38021 ornithine aminotransferase (401 aa), fasta scores, opt: 511, E(): 8.5e-27, (43.1% identity in 188 aa overlap), contains PS00600 Aminotransferases class-III pyridoxa (rocD2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2317Rv2322c, (MTCY3G12.12), len: 221. Probable rocD, similar to N-terminal region of ornithine aminotransferase len: 221, eg OAT_BACSU P38021 (401 aa) fasta scores, opt: 626, E(): 3.5e-32, (43.1% identity in 218 aa overlap); MTCY3G12.12 and .13 appear to be an ornit (rocD1) {Mycobacterium tuberculosis H37Rv (lab strain)}
2318Rv2323chypothetical protein Rv2323c {Mycobacterium tuberculosis H37Rv (lab strain)}
2319Rv2324hypothetical protein Rv2324 {Mycobacterium tuberculosis H37Rv (lab strain)}
2320Rv2325chypothetical protein Rv2325c {Mycobacterium tuberculosis H37Rv (lab strain)}
2321Rv2326chypothetical protein Rv2326c {Mycobacterium tuberculosis H37Rv (lab strain)}
2322Rv2327hypothetical protein Rv2327 {Mycobacterium tuberculosis H37Rv (lab strain)}
2323Rv2328, (MTCY3G12.06), len: 382. Member of M. tuberculosis PE family (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2324Rv2329c, (MTCY3G12.05), len: 515. narK1, probale nitrite extrusion protein. Equivalent to Z98741|MLCB22_25 Mycobacterium leprae cosmid B22; P (517 aa). FASTA score: opt: 2224 z-score: 2696.7 E(): 0; 69.3% identity in 488 aa overlap; similar to Z86089|MTCY6A4_5 M (narK1) {Mycobacterium tuberculosis H37Rv (lab strain)}
2325Rv2330c, (MTCY3G12.04), len: 175. Probable lipoprotein. Contains signal sequence and appropriately positioned PS00013 Prokaryoticmembrane lipoprotein lipid attachment site (PS00013). (lppP) {Mycobacterium tuberculosis H37Rv (lab strain)}
2326Rv2331hypothetical protein Rv2331 {Mycobacterium tuberculosis H37Rv (lab strain)}
2327Rv2332, (MTCY3G12.02c-MTCY98.01), len: 652. Probable malate oxidoreductase (EC 1.1.1.38) (MALIC ENZYME), similar to MAOX_BACSU P45868 probable malate oxidoreductase (nad) (582 aa) fasta scores, opt: 1849, E(): 0, (50.5% identity in 543 aa overlap) (mez) {Mycobacterium tuberculosis H37Rv (lab strain)}
2328Rv2333chypothetical protein Rv2333c {Mycobacterium tuberculosis H37Rv (lab strain)}
2329Rv2334, (MTCY98.03), len: 310 aa. cysK, probable cysteine synthase. FASTA best: G540497 Cysteine synthase (325aa), fasta scores, opt: 1223, E(): 0, (59.5% identity in 309 aa overlap). Also shows good similarity to MTCY130.21, (323 aa), fasta scores, opt: 662, E (cysK) {Mycobacterium tuberculosis H37Rv (lab strain)}
2330Rv2335, (MTCY98.04), len: 229. cysE. Function: probable serine acetyltransferase. len: 229 aa. FASTA best: TR:G142363 G142363 ORF 7, (49.5% identity in 216 aa overlap). TBPARSE score is 0.894; contains PS00101 Bacterial hexapeptide-repeat containing-transferase (cysE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2331Rv2336hypothetical protein Rv2336 {Mycobacterium tuberculosis H37Rv (lab strain)}
2332Rv2337chypothetical protein Rv2337c {Mycobacterium tuberculosis H37Rv (lab strain)}
2333Rv2338c, (MTCY98.07c), len: 318 aa. Probable moeW. Some similarity to several molybdopterin biosynthesis proteins: FASTA scores: sp|O27613|O27613 MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MO (251 aa) opt: 309 z-score: 387.4 E(): 4.7e-14; 30.7% identity in 254 aa overla (moeW) {Mycobacterium tuberculosis H37Rv (lab strain)}
2334Rv2339, (MTCY98.08), len: 962 aa, Probable membraneprotein with strong similarity to others in M. leprae (YV34_MYCLE P54881; G699237 U1740AB and M. tuberculosis (MTCY20G9.34; MTCY48.08c; MTCY19G5.06), FASTA best: YV34_MYCLE P54881 hypothetical 105.2 kd protein (mmpL9) {Mycobacterium tuberculosis H37Rv (lab strain)}
2335Rv2340c, (MTCY98.09c), len: 413 aa. Member of M. tuberculosis PE_family, with similarity to Y03A_MYCTU Q10637; YW36_MYCTU Q10873; etc, FASTA best: E245019 hypothetical 49.6 kDa protein (603 aa), fasta scores, opt: 655, E(): 2.8e-21, (40.3% identity in 382 aa ove (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2336Rv2341, (MTCY98.10), len: 139 aa. Possible lipoprotein. FASTA best: putative M. tuberculosis lipoprotein, Z98260|MTCI61.11(185 aa) opt: 155; E(): 0.0021; (31.0% identity in 116 aa overlap) also similar to VLPA_MYCHR P29228 variant surface antigen a precursor (1 (lppQ) {Mycobacterium tuberculosis H37Rv (lab strain)}
2337Rv2342hypothetical protein Rv2342 {Mycobacterium tuberculosis H37Rv (lab strain)}
2338Rv2343c, (MTCY98.12c), len: 639.dnaG, DNA primase, FASTA best: E214045 dna primase, (498 aa), fasta scores, opt: 844, E(): 0, (35.5% identity in 501 aa overlap). TBPARSEscore is 0.894 (dnaG) {Mycobacterium tuberculosis H37Rv (lab strain)}
2339Rv2344c, (MTCY98.13c), len: 431 aa. dgt. Probable deoxyguanosine triphosphate hydrolase, with similarity to several deoxyguanosine triphosphate hydrolases. FASTA best: AF027507|AF027507_2 Mycobacterium smegmatis dGTPase (428 aa)opt: 1991 z-score: 2396.5 E(): 0; (dgt) {Mycobacterium tuberculosis H37Rv (lab strain)}
2340Rv2345hypothetical protein Rv2345 {Mycobacterium tuberculosis H37Rv (lab strain)}
2341Rv2346chypothetical protein Rv2346c {Mycobacterium tuberculosis H37Rv (lab strain)}
2342Rv2347chypothetical protein Rv2347c {Mycobacterium tuberculosis H37Rv (lab strain)}
2343Rv2348chypothetical protein Rv2348c {Mycobacterium tuberculosis H37Rv (lab strain)}
2344Rv2349c, (MTCY98.18c), len: 508 aa. plcC gene: related to precursors of several phospolipases C; highly similar to PlcA/B (MTCY98.19c and MTCY98.20c), FASTA best: G399586 phospholipase C (512 aa), opt: 2494, E(): 0, (68.1% identity in 514 aa overlap) TBPARSE sco (plcC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2345Rv2350c, (MTCY98.19c), len: 512 aa. plcB: related to precursors of several phospolipases C; highly similar to PlcA/C (MTCY98.18c, MTCY98.20c) and (MTCY28.21c), FASTA best: G399586 PHOSPHOLIPASE C (512 aa), opt: 2788, E(): 0. (75.5% identity in 514 aa overlap) TB (plcB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2346Rv2351c, (MTCY98.20c), len: 512. plcA or phlC gene:related to precursors of several phospolipases C; highly similar to PlcB/C (MTCY98.18c/MTCY98.19c),and (MTCY28.21c) identical to G399586 PHOSPHOLIPASE C (512 aa) (plcA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2347Rv2352c, (MTCY98.21c), len: 391. Member of PPE_family in M. tuberculosis. Other examples are Q10778, Q10540, Q11031, Q10813, P42611, (MTCY31.06c; MTCY48.17; MTCY02B10.25c; MTCY274.23c; MTCY03C7.23; MTCY98.22c, MTCY98.25c; MTCY03C7.24c) etc. Len: 391. FASTA best: (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2348Rv2353c, (MTCY98.22c), len: 354 aa. Member of large Gly, Ala, Asn-rich PPE family including Q10778, P42611, E64997, Q10540, E241779, Q10707, Q10637, (MTCY31.06c, MTCY48.17, MTCY02B10.25c, MTCY274.23c, MTCY03C7.23, MTCY98.25c, MTCY03C7.24c) etc. FASTA best: Y04H_ (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2349Rv2354hypothetical protein Rv2354 {Mycobacterium tuberculosis H37Rv (lab strain)}
2350Rv2355hypothetical protein Rv2355 {Mycobacterium tuberculosis H37Rv (lab strain)}
2351Rv2356c, (MTCY98.25), len: 615 aa. Member of large Gly, Ala, Asn-rich PPE_family, including Q10778, Q10540,E241779, P42611, Q10813, (MTCY31.06c, MTCY02B10.25c, MTCY274.23c, MTCY03C7.23, MTCY98., MTCY03C7.24c, MTCY03C7.17c) etc. FASTA best: Y04H_MYCTU Q10778 hypo (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2352Rv2357c, (MTCY27.23-MTCY98.26), len: 463 aa. glyS, similar to eg MYCOPLASMA PNEUMONIAE SYG_MYCPN P75425 glycyl-trna synthetase (ec 6.1.1.14) (449 aa), fasta scores, opt:1074 z-score: 1266.2 E(): 0, (39.4% identity in 454 aa overlap); contains PS00017 ATP/GTP-bin (glyS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2353Rv2358hypothetical protein Rv2358 {Mycobacterium tuberculosis H37Rv (lab strain)}
2354Rv2359, (MTCY27.21c), len: 130 aa. furB, similar toeg FUR_ECOLI P06975, ferric uptake regulation protein (148aa), fasta scores, opt: 322 z-score: 395.8 E(): 4.8e-15, (37.9% identity in 132 aa overlap) (furB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2355Rv2360chypothetical protein Rv2360c {Mycobacterium tuberculosis H37Rv (lab strain)}
2356Rv2361chypothetical protein Rv2361c {Mycobacterium tuberculosis H37Rv (lab strain)}
2357Rv2362chypothetical protein Rv2362c {Mycobacterium tuberculosis H37Rv (lab strain)}
2358Rv2363, (MTCY27.17c), len: 484 aa. amiA2, Putative amidase similar to eg AMI2_MYCTU Q11056 putative amidase cy50.19c (ec 3.5.1.4 (462 aa), fasta scores, opt: 1141 z-score: 1247.0 E(): 0, (45.6% identity in 454 aa overlap), contains PS00571 Amidases signature, P (amiA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2359Rv2364c, (MTCY27.16), len: 300 aa. Probable bex, similar to gtp-binding proteins eg BEX_BACSU P42182 bex protein. bacillus subtilis. 10/96 (301 aa), fasta scores, opt: 831 z-score: 900.7 E(): 0, (44.0% identity in 300 aa overlap), highly similar to Q49768 B1937_ (bex) {Mycobacterium tuberculosis H37Rv (lab strain)}
2360Rv2365chypothetical protein Rv2365c {Mycobacterium tuberculosis H37Rv (lab strain)}
2361Rv2366chypothetical protein Rv2366c {Mycobacterium tuberculosis H37Rv (lab strain)}
2362Rv2367chypothetical protein Rv2367c {Mycobacterium tuberculosis H37Rv (lab strain)}
2363Rv2368c, (MTCY27.12), len: 352 aa. phoH, highly similar to M. leprae Q49751 phoH, similar eg to PHOH_BACSU P46343 phoh protein homolog (319 aa), fasta scores, opt: 1014 z-score: 1159.0 E(): 0, (50.8% identity in 303 aa overlap);contains PS00017 ATP/GTP-binding s (phoH) {Mycobacterium tuberculosis H37Rv (lab strain)}
2364Rv2369chypothetical protein Rv2369c {Mycobacterium tuberculosis H37Rv (lab strain)}
2365Rv2370chypothetical protein Rv2370c {Mycobacterium tuberculosis H37Rv (lab strain)}
2366Rv2371, (MTCY27.09c), len: 61 aa. Member of M. tuberculosis PE family, fasta scores, opt: 204 z-score: 268.3 E(): 6.1e-08, (66.7% identity in 57 aa overlap) (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2367Rv2372chypothetical protein Rv2372c {Mycobacterium tuberculosis H37Rv (lab strain)}
2368Rv2373c, (MTCY27.07), len: 382 aa. dnaJ2, dnaJ homologue, similar to eg DNAJ_ECOLI P08622 dnaj protein (376 aa), fasta scores, opt: 964 z-score: 968.0 E(): 0, (43.9% identity in 351 aa overlap), also highly similar to M. leprae Q49762 B1937_F2_56 (378 aa), fasta (dnaJ2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2369Rv2374c, (MTCY27.06), hrcA, len: 343 aa. Almost identical to M. leprae Q49749 YGRP but conflict at C-terminus,similar to eg HRCA_BACSU P25499 heat-inducible transcription repressor (343 aa) opt: 538 z-score: 592.4 E(): 5.4e-26,(28.9% identity in 325 aa overlap) (hrcA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2370Rv2375hypothetical protein Rv2375 {Mycobacterium tuberculosis H37Rv (lab strain)}
2371Rv2376chypothetical protein Rv2376c {Mycobacterium tuberculosis H37Rv (lab strain)}
2372Rv2377c, (MTCY27.03), len: 71 aa. mbtH, possibly involved in mycobactin synthesis. Similar to ORF1 in J04216|ECOFE6_3 Escherichia coli enterochelin esterase (72 aa) opt: 141 z-score: 231.3 E(): 2.3e-05; 38.0% identity in 50aa overlap (mbtH) {Mycobacterium tuberculosis H37Rv (lab strain)}
2373Rv2378c, (MTCY27.02), len: 431 aa. mbtG, possibly involved in mycobactin synthesis as lysine N6:hydroxylase, weakly similar to sp|P11295|IUCD_ECOLI LYSINE N-HYDROXLYASE (EC 1.-.-.-) (426 aa) FASTA score; opt: 118 z-score: 147.0E(): 1.2; 20.8% identity in 346 aa (mbtG) {Mycobacterium tuberculosis H37Rv (lab strain)}
2374Rv2379c, (MTCY27.01), len: 1461 aa. mbtF, Mycobactin/Exochelin Synthesis (lysine ligation). similar to peptide synthases eg Q54959 PRISTINAMYCIN I SYNTHASE I. (2591 aa)opt: 984 z-score: 1040.1 E(): 0, (32.6% identity in 1561 aaoverlap); contains PS00455 Putative (mbtF) {Mycobacterium tuberculosis H37Rv (lab strain)}
2375Rv2380c, (MTCY22H8.05), len: 1682. mbtE, probably involved in Mycobactin/Exochelin Synthesis (lysine ligation), similar to G466458 PYOVERDINE SYNTHETASE D (2448 aa) fasta scores, opt: 1833, E(): 0, (33.7% identity in 1649 aa overlap); contains PS00455 Putative A (mbtE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2376Rv2381c, (MTCY22H8.04), len: 1004. mbtD, probably involved in Mycobactin/Exochelin Synthesis. Similar eg to part of ERY3_SACER Q03133 erythronolide synthase, (3170 aa), fasta scores, opt: 1150, E(): (31.6% identity in 1041 aa overlap); contains PS00012 Phosphopa (mbtD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2377Rv2382c, (MTCY22H8.03), len: 444. mbtC, probably involved in Mycobactin/Exochelin Synthesis, similar to part of ERY3_SACER Q03133 erythronolide synthase, (module 6) (3170 aa) opt: 1368, E(): 0, (49.8% identity in 444 aa overlap) (mbtC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2378Rv2383c, (MTCY22H8.02), len: 1414. mbtB, probably involved in Mycobactin/Exochelin Synthesis (serine/threonineligation), similar to HMP2_YEREN P48633 high-molecular-weight protein 2 (2035 aa), fasta scores, opt: 2275, E(): 0, (38.4% identity in 1069 aa overlap); (mbtB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2379Rv2384, (MTCY22H8.01-MTCY253.37c), len: 565. mbtA, probably involved in Mycobactin/Exochelin Synthesis (salicylate-AMP ligase), similar to DHBE_BACSU P40871 2,3-dihydroxybenzoate-amp ligase (539 aa), fasta scores, opt: 1314, E(): 0, (45.9% identity in 442 aa ov (mbtA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2380Rv2385, (MTCY253.36c), len: 306, Probable esterase/acetyl hydrolase, similar to MTCY13E12.41c gp|Z95390|MTY13E12_40 Mycobacterium tuberculosis cosmi (277 aa) FASTA score: opt: 468 z-score: 555.3 E(): 2.1e-23; 36.2% identityin 254 aa overlap; also similar to eg (lipK) {Mycobacterium tuberculosis H37Rv (lab strain)}
2381Rv2386c, (MTCY253.35), len: 450. Possible trpE , similar to many eg TRPE_BACSU P03963 anthranilate synthase component i (515 aa), fasta scores, opt: 441, E(): 8.2e-22, (30.0% identity in 293 aa overlap) (trpE2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2382Rv2387hypothetical protein Rv2387 {Mycobacterium tuberculosis H37Rv (lab strain)}
2383Rv2388c, (MTCY253.33), len: 375. Probable hemN similar to sp|P54304|HEMN_BACSU PROBABLE OXYGEN-INDEPENDENT COPRO (366 aa) fasta scores, opt: 668 z-score: 815.2 E(): 0; 34.9% identity in 327 aa overlap; and YGGW_ECOLI P52062 hypothetical 42.6 kd protein in gshb- (hemN) {Mycobacterium tuberculosis H37Rv (lab strain)}
2384Rv2389chypothetical protein Rv2389c {Mycobacterium tuberculosis H37Rv (lab strain)}
2385Rv2390chypothetical protein Rv2390c {Mycobacterium tuberculosis H37Rv (lab strain)}
2386Rv2391, (MTCY253.30c), len: 563, Possible nitrite reductase similar to many eg D31732|PEENIRNRT_1 Plectonema boryanum nitrite reductase (654 aa), fasta scores, opt: 805,E(): 0, (31.7% identity in 517 aa overlap) (nirA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2387Rv2392, (MTCY253.29c), len: 254. Probable cysH, 3-phosphoadenylylsulfate reductase similar to many eg METG_SCHPO Q10270 putative 3-phosphoadenylylsulfate reductase (266 aa), fasta scores, opt: 343, E(): 3.4e-15, (29.9% identity in 261 aa overlap) (cysH) {Mycobacterium tuberculosis H37Rv (lab strain)}
2388Rv2393hypothetical protein Rv2393 {Mycobacterium tuberculosis H37Rv (lab strain)}
2389Rv2394, (MTCY253.27c), len: 643. ggtB, Probable gamma-glutamyltranspeptidase precursor, has potential signal peptide and appropriately positioned prokaryotic lipoproteinattachment site (PS00013), similar to eg GGT_BACSU P54422 gamma-glutamyltranspeptidase precu (ggtB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2390Rv2395hypothetical protein Rv2395 {Mycobacterium tuberculosis H37Rv (lab strain)}
2391Rv2396, (MTCY253.25c), len: 361. Member of PE family, PGRS subfamily gly rich protein, len: 361, similar to egY03A_MYCTU Q10637 hypothetical glycine-rich 49.6 kd pro (603 aa), fasta scores, opt: 1144, E(): 2.2e-40, (54.8% identity in 372 aa overlap); contains P (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2392Rv2397c, (MTCY253.24), len: 351. Probable cysA, similar to eg CYSA_ECOLI P16676 sulfate transport atp-binding protein (365 aa), fasta scores, opt: 903, E(): 0, (47.3% identity in 313 aa overlap); contains PS00017 ATP/GTP-bindingsite motif A, PS00211 ABC transpor (cysA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2393Rv2398c, (MTCY253.23), len: 272. Probable cysW, similar to eg CYSW_SYNP7 P27370 sulfate transport system permease protein cysW, (286 aa), fasta scores, opt: 757, E(): 0,(44.3% identity in 264 aa overlap); contains PS00402 Binding-protein-dependent transport syst (cysW) {Mycobacterium tuberculosis H37Rv (lab strain)}
2394Rv2399c, (MTCY253.22), len: 283. Probable cysT, similar to eg CYST_ECOLI P16701 sulfate transport system permease protein cysT,(277 aa), fasta scores, opt: 669, E(): 3.3e-36, (40.0% identity in 260 aa overlap); contains PS00402 Binding-protein-dependent transpor (cysT) {Mycobacterium tuberculosis H37Rv (lab strain)}
2395Rv2400c, (MTCY253.21), len: 356. Probable subI, (thio)sulphate binding protein, similar to eg G466966 subI, sulphate binding precursor, (358 aa), fasta scores, opt: 1775, E(): 0, (76.5% identity in 340 aa overlap) (subI) {Mycobacterium tuberculosis H37Rv (lab strain)}
2396Rv2401hypothetical protein Rv2401 {Mycobacterium tuberculosis H37Rv (lab strain)}
2397Rv2402hypothetical protein Rv2402 {Mycobacterium tuberculosis H37Rv (lab strain)}
2398Rv2403c, (MTCY253.17), len: 251. Probable lipoprotein, has signal peptide and appropriatelypositioned prokaryotic lipoprotein attachment site (PS00013). Similar to C-terminal part of sp|Q11053|K08G_MYCTU PROBABLE SERINE/THREONINE-PROTEIN (626 aa) fasta scores: o (lppR) {Mycobacterium tuberculosis H37Rv (lab strain)}
2399Rv2404c, (MTCY253.16), len: 653 Probable lepA, highly similar to LEPA_MYCLE P53530 gtp-binding protein lepa. lepa or b19 (646 aa), fasta scores, opt: 3610, E(): 0, (88.0% identity in 649 aa overlap); contains PS00017 ATP/GTP-binding site motif A, PS00301 GTP-bin (lepA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2400Rv2405hypothetical protein Rv2405 {Mycobacterium tuberculosis H37Rv (lab strain)}
2401Rv2406chypothetical protein Rv2406c {Mycobacterium tuberculosis H37Rv (lab strain)}
2402Rv2407hypothetical protein Rv2407 {Mycobacterium tuberculosis H37Rv (lab strain)}
2403Rv2408, (MTCY253.12c), len: 239. Possibly member ofPE family similar to, eg YW36_MYCTU Q10873 hypothetical 53.7 kd protein cy39.36c (558 aa), fasta scores, opt: 212, E(): 5.1e-05, (35.2% identity in 162 aa overlap) (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2404Rv2409chypothetical protein Rv2409c {Mycobacterium tuberculosis H37Rv (lab strain)}
2405Rv2410chypothetical protein Rv2410c {Mycobacterium tuberculosis H37Rv (lab strain)}
2406Rv2411chypothetical protein Rv2411c {Mycobacterium tuberculosis H37Rv (lab strain)}
2407Rv2412, (MTCY253.08c), len: 86 aa. rpsT, 30s ribosomal protein s20; highly similar to many eg. RS20_ECOLI P02378 30s ribosomal protein s20 (86 aa), fasta scores; opt: 210 z-score: 411.7 E(): 2.3e-16, 42.4% identity in 85 aa overlap (rpsT) {Mycobacterium tuberculosis H37Rv (lab strain)}
2408Rv2413chypothetical protein Rv2413c {Mycobacterium tuberculosis H37Rv (lab strain)}
2409Rv2414chypothetical protein Rv2414c {Mycobacterium tuberculosis H37Rv (lab strain)}
2410Rv2415chypothetical protein Rv2415c {Mycobacterium tuberculosis H37Rv (lab strain)}
2411Rv2416chypothetical protein Rv2416c {Mycobacterium tuberculosis H37Rv (lab strain)}
2412Rv2417chypothetical protein Rv2417c {Mycobacterium tuberculosis H37Rv (lab strain)}
2413Rv2418chypothetical protein Rv2418c {Mycobacterium tuberculosis H37Rv (lab strain)}
2414Rv2419chypothetical protein Rv2419c {Mycobacterium tuberculosis H37Rv (lab strain)}
2415Rv2420chypothetical protein Rv2420c {Mycobacterium tuberculosis H37Rv (lab strain)}
2416Rv2421chypothetical protein Rv2421c {Mycobacterium tuberculosis H37Rv (lab strain)}
2417Rv2422hypothetical protein Rv2422 {Mycobacterium tuberculosis H37Rv (lab strain)}
2418Rv2423hypothetical protein Rv2423 {Mycobacterium tuberculosis H37Rv (lab strain)}
2419Rv2424chypothetical protein Rv2424c {Mycobacterium tuberculosis H37Rv (lab strain)}
2420Rv2425chypothetical protein Rv2425c {Mycobacterium tuberculosis H37Rv (lab strain)}
2421Rv2426chypothetical protein Rv2426c {Mycobacterium tuberculosis H37Rv (lab strain)}
2422Rv2427c, (MTCY428.20), len: 415. Probable proA, similar to eg PROA_ECOLI P07004 gamma-glutamyl phosphate reductase (407 aa), fasta scores, opt: 1034, E(): 0, (47.1% identity in 403 aa overlap) (proA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2423Rv2428, (MTCY428.18c), len: 195. ahpC gene, alkyl hydroperoxide reductase, identical to G1172078 AHPC (ahpC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2424Rv2429, (MTCY428.17c), 177 aa. ahpD gene, identicalto G1174227 AHPD (ahpD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2425Rv2430c, (MTCY428.16), len: 194. Member of PPE family, similar to PPE e.g. Y07P_MYCTU Q11031 hypothetical 40.0 kd protein cy02b10. (396 aa), fasta scores, opt: 350, E(): 4.7e-16, (35.6% identity in 174 aa overlap) (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2426Rv2431c, (MTCY428.15), len: 99. Member of PE familysimilar to eg G913039 orf 3 OF PGRS repeat (100 aa), fastascores, opt: 168, E(): 4.2e-06, (34.7% identity in 95 aa overlap) (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2427Rv2432chypothetical protein Rv2432c {Mycobacterium tuberculosis H37Rv (lab strain)}
2428Rv2433chypothetical protein Rv2433c {Mycobacterium tuberculosis H37Rv (lab strain)}
2429Rv2434chypothetical protein Rv2434c {Mycobacterium tuberculosis H37Rv (lab strain)}
2430Rv2435chypothetical protein Rv2435c {Mycobacterium tuberculosis H37Rv (lab strain)}
2431Rv2436, (MTCY428.10c), len: 304. Probable ribokinase, rbsK, similar to eg RBSK_ECOLI P05054 ribokinase (309 aa), fasta scores,opt: 387, E(): 1.3e-16, (34.7% identity in 314 aa overlap), contains PS00583 pfkB family of carbohydrate kinases signature 1 (rbsK) {Mycobacterium tuberculosis H37Rv (lab strain)}
2432Rv2437hypothetical protein Rv2437 {Mycobacterium tuberculosis H37Rv (lab strain)}
2433Rv2438chypothetical protein Rv2438c {Mycobacterium tuberculosis H37Rv (lab strain)}
2434Rv2439c, (MTCY428.07), len: 376. Probable proB, glutamate 5-kinase, similar to eg PROB_CORGL P46546 glutamate 5-kinase (369 aa), fasta scores, opt: 1241, E(): 0, (54.3% identity in 368 aa overlap); contains PS00902 Glutamate 5-kinase signature (proB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2435Rv2440c, (MTCY428.06), len: 479. Probable obg, nucleotide-binding protein, equivalent to Streptomyces griseus D87916|D87916_3 (478 aa) fasta scores, opt: 1328 z-score: 1443.0 E(): 0; 58.9% identity in 479 aa overlap; also similar to eg OBG_BACSU P20964 spo0b-ass (obg) {Mycobacterium tuberculosis H37Rv (lab strain)}
2436Rv2441c, (MTCY428.05), len: 86. Probable rpmA, similar to eg RL27_ECOLI P02427 50s ribosomal protein l27, (84 aa), fasta scores, opt: 328, E(): 7.1e-17, (64.2% identity in 81 aa overlap); contains PS00831 Ribosomal protein L27 signature (rpmA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2437Rv2442c, (MTCY428.04), len: 104. Probable rplU, similar eg to RL21_ECOLI P02422 50s ribosomal protein l21 (103 aa), fasta scores, opt: 250, E(): 4e-11, (37.6% identity in 101 aa overlap) (rplU) {Mycobacterium tuberculosis H37Rv (lab strain)}
2438Rv2443, (MTCY428.03c), len: 491. dctA, Similar eg to DCTA_SALTY P50334 c4-dicarboxylate transport protein (428 aa), fasta scores, opt: 1241, E(): 0, (46.9% identity in 414 aa overlap) (dctA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2439Rv2444c, (MTCY428.02), len: 953. Similar at C-terminus to RNE_ECOLI P21513 ribonuclease e (1061 aa), fasta scores, opt: 554, E(): 9.8e-22, (37.8% identity in 386 aa overlap) (rne) {Mycobacterium tuberculosis H37Rv (lab strain)}
2440Rv2445c, (MTV008.01c-MTCY428.01), len: 136. Probable ndk, nucleoside diphosphate kinase,; highly similar to many eg. NDK_STRCO P50589 nucleoside diphosphate kinase (ec 2.7.4.6) from Streptomyces coelicolor (137 aa), fasta scores; opt: 367 z-score: 662.8 E(): 1e- (ndkA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2441Rv2446chypothetical protein Rv2446c {Mycobacterium tuberculosis H37Rv (lab strain)}
2442Rv2447c, (MTV008.03c), len: 487 aa. folC, probable folylpolyglutamate synthase; similar to many eg. Streptomyces coelicolor TR:O08416 (EMBL:Y13070) FOLYLPOLYGLUTAMATE SYNTHASE (EC 6.3.2.17) (444 aa), fasta scores; opt: 768 z-score: 1538.6 E(): 0, 53.2% identity (folC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2443Rv2448c, (MTV008.04c), len: 876. valS, valyl-tRNA synthetase similar to many eg. SYV_ECOLI P07118 valyl-trna synthetase (ec 6.1.1.9) (951 aa), fasta scores; opt: 1183 z-score: 2335.4 E(): 0, 43.7% identity in 945 aa overlap. Contains PS00178 Aminoacyl-transfer R (valS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2444Rv2449chypothetical protein Rv2449c {Mycobacterium tuberculosis H37Rv (lab strain)}
2445Rv2450chypothetical protein Rv2450c {Mycobacterium tuberculosis H37Rv (lab strain)}
2446Rv2451hypothetical protein Rv2451 {Mycobacterium tuberculosis H37Rv (lab strain)}
2447Rv2452chypothetical protein Rv2452c {Mycobacterium tuberculosis H37Rv (lab strain)}
2448Rv2453chypothetical protein Rv2453c {Mycobacterium tuberculosis H37Rv (lab strain)}
2449Rv2454chypothetical protein Rv2454c {Mycobacterium tuberculosis H37Rv (lab strain)}
2450Rv2455chypothetical protein Rv2455c {Mycobacterium tuberculosis H37Rv (lab strain)}
2451Rv2456chypothetical protein Rv2456c {Mycobacterium tuberculosis H37Rv (lab strain)}
2452Rv2457c, (MTV008.13c), len: 426 aa. Probable clpX, atp-dependent clp protease atp-binding subunit clpX highly similar to many eg. CLPX_ECOLI P33138 atp-dependent clp protease atp-binding subunit clpX (423 aa), fasta scores; opt:1694 z-score: 2321.3 E(): 0, 62.4% (clpX) {Mycobacterium tuberculosis H37Rv (lab strain)}
2453Rv2458hypothetical protein Rv2458 {Mycobacterium tuberculosis H37Rv (lab strain)}
2454Rv2459hypothetical protein Rv2459 {Mycobacterium tuberculosis H37Rv (lab strain)}
2455Rv2460c, (MTV008.16c), len: 214 aa. clpP2, atp-dependent clp protease proteolytic subunit; highly similar to many eg. CLPP_ECOLI P19245 atp-dependent clp protease proteolytic subunit (EC 3.4.21.92) (207 aa), fasta scores; opt: 639 z-score: 950.2 E(): 0, 49.7% id (clpP2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2456Rv2461c, (MTV008.17c), len: 200aa. clpP, atp-dependent clp protease proteolytic subunit; highly similar to many eg. CLPP_ECOLI P19245 atp-dependent clp protease proteolytiic subunit (EC 3.4.21.92) (207 aa), fasta scores; opt: 636 z-score: 1081.5 E(): 0, 53.5% id (clpP) {Mycobacterium tuberculosis H37Rv (lab strain)}
2457Rv2462c, (MTV008.18c), len: 466 aa. tig, possible chaperone protein; similar to trigger factor from several organisms eg. TIG_BACSU P80698 trigger factor (tf) (423 aa), fasta scores; opt: 648 z-score: 578.2 E(): 5.2e-25, 29.9% identity in 411 aa overlap (tig) {Mycobacterium tuberculosis H37Rv (lab strain)}
2458Rv2463, (MTV008.19), len: 394 aa. Probable esterase; similar to esterases from Pseudomonas spp. eg. TR:Q52467 (EMBL:M68491) esterase (389 aa), fasta scores; opt: 811 z-score: 951.6 E(): 0, 37.2% identity in 379 aa overlap. Also similar to other M. tuberculosis (lipP) {Mycobacterium tuberculosis H37Rv (lab strain)}
2459Rv2464chypothetical protein Rv2464c {Mycobacterium tuberculosis H37Rv (lab strain)}
2460Rv2465c, (MTV008.21c), len: 162 aa. Probable isomerase, rpi; similar to several diverse isomerases eg. LACB_STAAU P26592 galactose-6-phosphate isomerase lacb (171 aa), fasta scores; opt: 296 z-score: 444.4 E(): 1.5e-17, 35.4% identity in 158 aa overlap and RPIB_ (rpi) {Mycobacterium tuberculosis H37Rv (lab strain)}
2461Rv2466chypothetical protein Rv2466c {Mycobacterium tuberculosis H37Rv (lab strain)}
2462Rv2467, (MTV008.23), len: 861 aa. pepD, probable aminopeptidase; similar to many eg. Streptomyces lividans AMPN_STRLI Q11010 aminopeptidase n (ec 3.4.11.2) (lysyl aminopeptidase) (857 aa), fasta scores; opt: 2839 z-score: 3205.0E(): 0, 53.2% identity in 864 aa (pepD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2463Rv2468chypothetical protein Rv2468c {Mycobacterium tuberculosis H37Rv (lab strain)}
2464Rv2469chypothetical protein Rv2469c {Mycobacterium tuberculosis H37Rv (lab strain)}
2465Rv2470, (MTV008.26), len: 128 aa. glbO, possible globin; weakly similar to eg. GLBN_NOSSN P52335 cyanoglobin from nostoc sp. (118 aa), fasta scores; opt: 138 z-score: 216.7 E(): 7.1e-05, 26.6% identity in 94 aa overlap. Also similar to B. subtilis sp|O31607|O31 (glbO) {Mycobacterium tuberculosis H37Rv (lab strain)}
2466Rv2471hypothetical protein Rv2471 {Mycobacterium tuberculosis H37Rv (lab strain)}
2467Rv2472hypothetical protein Rv2472 {Mycobacterium tuberculosis H37Rv (lab strain)}
2468Rv2473hypothetical protein Rv2473 {Mycobacterium tuberculosis H37Rv (lab strain)}
2469Rv2474chypothetical protein Rv2474c {Mycobacterium tuberculosis H37Rv (lab strain)}
2470Rv2475chypothetical protein Rv2475c {Mycobacterium tuberculosis H37Rv (lab strain)}
2471Rv2476chypothetical protein Rv2476c {Mycobacterium tuberculosis H37Rv (lab strain)}
2472Rv2477chypothetical protein Rv2477c {Mycobacterium tuberculosis H37Rv (lab strain)}
2473Rv2478chypothetical protein Rv2478c {Mycobacterium tuberculosis H37Rv (lab strain)}
2474Rv2479chypothetical protein Rv2479c {Mycobacterium tuberculosis H37Rv (lab strain)}
2475Rv2480chypothetical protein Rv2480c {Mycobacterium tuberculosis H37Rv (lab strain)}
2476Rv2481chypothetical protein Rv2481c {Mycobacterium tuberculosis H37Rv (lab strain)}
2477Rv2482c, (MTV008.38c), len: 789. Probable plsB2, glycerol-3-phosphate acyltransferase; similar to many eg. PLSB_ECOLI P00482 glycerol-3-phosphate acyltransferase (827 aa), fasta scores; opt: 521 z-score: 573.9 E(): 9e-25, 24.1%identity in 611 aa overlap. Also si (plsB2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2478Rv2483chypothetical protein Rv2483c {Mycobacterium tuberculosis H37Rv (lab strain)}
2479Rv2484chypothetical protein Rv2484c {Mycobacterium tuberculosis H37Rv (lab strain)}
2480Rv2485c, (MTV008.41c), len: 421 aa. Unknown; similar to several M. tuberculosis hypothetical proteins eg. TR:O06832 (EMBL;Z95844) MTCY493.28 (420 aa), fasta scores; opt:1083 z-score: 1304.9 E(): 0, 46.3% identity in 380 aa overlap and, in part, to several carbox (lipQ) {Mycobacterium tuberculosis H37Rv (lab strain)}
2481Rv2486, (MTV008.42), len: 256. echA14, possible enoyl-coA hydratase; similar to many eg. ECHH_RHOCA P24162 probable enoyl-coa hydratase (257 aa), fasta scores; opt: 453 z-score: 544.7 E(): 3.8e-23, 39.4% identity in 259 aa overlap. Contains PS00166 Enoyl-CoA hy (echA14) {Mycobacterium tuberculosis H37Rv (lab strain)}
2482Rv2487c, (MTV008.43c), len: 694 aa. Member of the PE family, PGRS-subfamily of Gly-rich proteins; similar to many eg. TR:O06810 MTCY493.04 (EMBL:Z95844) (1329 aa), fastascores; opt: 1597 z-score: 746.8 E(): 0, 51.6% identity in764 aa overlap (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2483Rv2488chypothetical protein Rv2488c {Mycobacterium tuberculosis H37Rv (lab strain)}
2484Rv2489chypothetical protein Rv2489c {Mycobacterium tuberculosis H37Rv (lab strain)}
2485Rv2490c, (MTV008.46c), len: 1660 aa. Member of the M. tuberculosis PE family, PGRS-subfamily of Gly-rich proteins; similar to many eg. YQ04_MYCTU P71933 hypothetical 63.1 kd glycine-rich protein (778 aa), fasta scores; opt: 2352z-score: 915.0 E(): 0, 50.5% ident (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2486Rv2491hypothetical protein Rv2491 {Mycobacterium tuberculosis H37Rv (lab strain)}
2487Rv2492hypothetical protein Rv2492 {Mycobacterium tuberculosis H37Rv (lab strain)}
2488Rv2493hypothetical protein Rv2493 {Mycobacterium tuberculosis H37Rv (lab strain)}
2489Rv2494hypothetical protein Rv2494 {Mycobacterium tuberculosis H37Rv (lab strain)}
2490Rv2495c, (MTCY07A7.01c-MTV008.51c), len: 393. pdhC,similar to eg SUCB NEISSERIA GONORRHOEAE Q50993 (393 aa) opt: 509 z-score: 568.9 E(): 1.1e-24, (32.3% identity in 371aa overlap), ODP2_BACST P11961 dihydrolipoamide acetyltransferase component (e2) of pyruvate d (pdhC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2491Rv2496c, (MTCY07A7.02c), len: 348 aa. pdhB, similar to eg ODPB_BACST P21874 pyruvate dehydrogenase e1 component, BETA SUBUNIT (EC 1.2.4.1) (324 aa), fasta scores, opt: 951 z-score: 1108.3 E(): 0, (47.7% identity in 321 aa overlap) (pdhB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2492Rv2497c, (MTCY07A7.03c), len: 367 aa. pdhA, smilar to eg ODPA_ACHLA P35485 pyruvate dehydrogenase e1 componentALPHA SUBUNIT (EC 1.2.4.1) (345 aa) fasta scores, opt: 890z-score: 1048.0 E(): 0, (43.0% identity in 330 aa overlap) (pdhA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2493Rv2498c, (MTCY07A7.04c), len: 373 aa. similar to egCILB_ECOLI P77770 citrate lyase beta chain (ec 4.1.3.6) (307 aa) opt: 265 z-score: 315.6 E(): 1.5e-10, (32.8% identityin 265 aa overlap), similar to MTCY22D7.06, (35.2% identityin 264 aa overlap) (citE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2494Rv2499chypothetical protein Rv2499c {Mycobacterium tuberculosis H37Rv (lab strain)}
2495Rv2500c, (MTCY07A7.06c), len: 394 aa. fadE19 acyl-coa dehydrogenase, also known as mmgC, similar to eg ACDB_BACSU P45857 acyl-coa dehydrogenase (ec 1.3.99.-). (379 aa),fasta scores, opt: 983 z-score: 1116.6 E(): 0, (43.7% identity in 373 aa overlap), contains PS (fadE19) {Mycobacterium tuberculosis H37Rv (lab strain)}
2496Rv2501c, (MTCY07A7.07c), len: 654 aa, accA1, also known as bccA, BCCA_MYCTU P46401 acetyl-/propionyl-coenzyme a carboxylase alpha chain; contains PS00188 Biotin-requiring enzymes attachment site, PS00866 Carbamoyl-phosphate synthase subdomain signature 1, PS0086 (accA1) {Mycobacterium tuberculosis H37Rv (lab strain)}
2497Rv2502c, (MTCY07A7.08c), len: 529 aa. accD1, Acetyl/Propionyl-CoA Carboxylase, Beta Subunit, most similar to YLP5_CAEEL P34385 hypothetical 66.5 kd protein f02a9.5 (608 aa), fasta scores opt: 2217 z-score: 2538.1 E(): 0, (62.6% identity in 516 aa overlap), simil (accD1) {Mycobacterium tuberculosis H37Rv (lab strain)}
2498Rv2503c, (MTCY07A7.09c), len: 218 aa. scoB, 3-Oxo Acid:CoA Transferase, B Subunit similar to eg PCAJ_BACSU P42316 probable 3-oxoadipate coa-transferase SUBUNIT B (EC 2.8.3.6) (216 aa) opt: 820 z-score: 990.7 E(): 0, (58.2% identity in 201 aa overlap) (scoB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2499Rv2504c, (MTCY07A7.10c), len: 248 aa. scoA, 3-Oxo Acid:CoA Transferase, A Subunit, similar to eg PCAI_BACSU P42315 probable 3-oxoadipate coa-transferase SUBUNIT A (EC 2.8.3.6) (238 aa) opt: 562 z-score: 664.0 E(): 5.7e-30, (55.6% identity in 248 aa overlap) (scoA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2500Rv2505c, (MTCY07A7.11c), len: 547 aa. fadD35, Acyl-CoA Synthetase, similar to eg YDID_ECOLI P38135 hypothetical 62.8 kd protein in arod- (566 aa) fasta scores, opt: 852 z-score: 984.7 E(): 0, (32.5% identity in 499 aa overlap) (fadD35) {Mycobacterium tuberculosis H37Rv (lab strain)}
2501Rv2506hypothetical protein Rv2506 {Mycobacterium tuberculosis H37Rv (lab strain)}
2502Rv2507hypothetical protein Rv2507 {Mycobacterium tuberculosis H37Rv (lab strain)}
2503Rv2508chypothetical protein Rv2508c {Mycobacterium tuberculosis H37Rv (lab strain)}
2504Rv2509hypothetical protein Rv2509 {Mycobacterium tuberculosis H37Rv (lab strain)}
2505Rv2510chypothetical protein Rv2510c {Mycobacterium tuberculosis H37Rv (lab strain)}
2506Rv2511hypothetical protein Rv2511 {Mycobacterium tuberculosis H37Rv (lab strain)}
2507Rv2512chypothetical protein Rv2512c {Mycobacterium tuberculosis H37Rv (lab strain)}
2508Rv2513hypothetical protein Rv2513 {Mycobacterium tuberculosis H37Rv (lab strain)}
2509Rv2514chypothetical protein Rv2514c {Mycobacterium tuberculosis H37Rv (lab strain)}
2510Rv2515chypothetical protein Rv2515c {Mycobacterium tuberculosis H37Rv (lab strain)}
2511Rv2516chypothetical protein Rv2516c {Mycobacterium tuberculosis H37Rv (lab strain)}
2512Rv2517chypothetical protein Rv2517c {Mycobacterium tuberculosis H37Rv (lab strain)}
2513Rv2518c, (MTV009.03c), len: 408. Unknown but similar to several hypothetical mycobacterial proteins and equivalent to Mycobacterium leprae protein MLCL383.33; len: 414 aa; also similar to YV09_MYCTU Q11149 hypothetical 47.9 kd protein cY20G9.09 (451 aa). FASTA s (lppS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2514Rv2519, (MTV009.04), len: 492. Member of Gly, Ala-rich PE family. FASTA scores: sp|Q50630|Y0BA_MYCTU HYPOTHETICAL GLYCINE-RICH 46.3 KD (543 aa) opt: 848 z-score: 659.2 E(): 3.1e-29; 39.9% identity in 451 aa overlap. TBparse score is 0.918 (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2515Rv2520chypothetical protein Rv2520c {Mycobacterium tuberculosis H37Rv (lab strain)}
2516Rv2521, (MTV009.06), len: 157. Bcp, member of the AHPC/TSA family, equivalent to Mycobacterium leprae Bcp; MLCL383.31c, bcp, bacterioferritin comigratory protein, len: 161 aa; highly similar to eg. BCP_ECOLI P23480 bacterioferritin comigratory protein. (156 aa) (bcp) {Mycobacterium tuberculosis H37Rv (lab strain)}
2517Rv2522chypothetical protein Rv2522c {Mycobacterium tuberculosis H37Rv (lab strain)}
2518Rv2523c, (MTV009.08c), len: 130. acpS, Probable CoA:apo-[Acyl Carrier Protein] Pantethienephosphotransferase, similar to several e.g. P24224|ACPS_ECOLI. FASTA scores: sp|P24224|ACPS_ECOLI HOLO-[ACYL-CARRIER PROTEIN] SYNTH (126 aa) opt: 158 z-score: 212.8 E(): 0. (acpS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2519Rv2524c, (MTCY159.32-MTV009.09c), len: 3069. fas Fatty Acid Synthase, similar to eg G580746 fatty acid synthase (3104 aa), fasta scores, opt: 3867, E(): 0, (50.0% identity in 3032 aa overlap), contains PS00017 ATP/GTP-binding site motif A, PS00606 Beta-ketoacyl (fas) {Mycobacterium tuberculosis H37Rv (lab strain)}
2520Rv2525chypothetical protein Rv2525c {Mycobacterium tuberculosis H37Rv (lab strain)}
2521Rv2526hypothetical protein Rv2526 {Mycobacterium tuberculosis H37Rv (lab strain)}
2522Rv2527hypothetical protein Rv2527 {Mycobacterium tuberculosis H37Rv (lab strain)}
2523Rv2528c, (MTCY159.28), len: 306 aa. Probable mrr, similar to MRR_ECOLI P24202 mrr restriction system protein, (304 aa), fasta scores, opt: 647, E(): 0, (35.3% identity in 309 aa overlap) (mrr) {Mycobacterium tuberculosis H37Rv (lab strain)}
2524Rv2529hypothetical protein Rv2529 {Mycobacterium tuberculosis H37Rv (lab strain)}
2525Rv2530chypothetical protein Rv2530c {Mycobacterium tuberculosis H37Rv (lab strain)}
2526Rv2531c, (MTCY159.25), len: 947 aa. Possible adi, ornithine/arginine decarboxylase, similar to eg DCOR_ECOLI P21169 ornithine decarboxylase, constitutive (731 aa), fasta scores, opt: 396, E(): 4.4e-18, (27.8% identity in 648 aaoverlap) (adi) {Mycobacterium tuberculosis H37Rv (lab strain)}
2527Rv2532chypothetical protein Rv2532c {Mycobacterium tuberculosis H37Rv (lab strain)}
2528Rv2533c, (MTCY159.23), len: 156 aa. nusB, similar to eg NUSB_BACSU P54520 n utilization substance protein b hom (131 aa), fasta scores, opt: 315, E(): 5.4e-15, (39.5% identity in 129 aa overlap) (nusB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2529Rv2534c, (MTCY159.22), len: 187 aa. efp, similar toG1001112 hypothetical 20.4 kDa protein (187 aa), opt: 649,E(): 0, (50.3% identity in 185 aa overlap); also elongation factors eg EFP_ECOLI P33398 elongation factor p (ef-p), (187 aa), opt: 503, E(): 1.8e-27, (42 (efp) {Mycobacterium tuberculosis H37Rv (lab strain)}
2530Rv2535c, (MTCY159.21), len: 372 aa. Probable pepQ, cytoplasmic peptidas, similar eg to YQHT_BACSU P54518 putative peptidase in gcvt-spoiii (353 aa), fasta scores, opt: 781, E(): 0, (40.1% identity in 354 aa overlap) also similarto MTCY49.29c (33.9% identity in 3 (pepQ) {Mycobacterium tuberculosis H37Rv (lab strain)}
2531Rv2536hypothetical protein Rv2536 {Mycobacterium tuberculosis H37Rv (lab strain)}
2532Rv2537c, (MTCY159.19), len: 147 aa. aroD, almost identical to AROD_MYCTU P36918 3-dehydroquinate dehydratase; contains PS01029 Dehydroquinase class II signature (aroD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2533Rv2538c, (MTCY159.18), len: 362. aroB, almost identical to AROB_MYCTU P36919 3-dehydroquinate synthase (aroB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2534Rv2539c, (MTCY159.17), len: 176 aa. aroK, similar to eg AROK_ECOLI P24167 shikimate kinase i, (172 aa), fasta scores, opt: 316, E(): 1.3e-13, (39.4% identity in 165 aa overlap); contains PS00017 ATP/GTP-binding site motif A, PS01128 Shikimate kinase signature (aroK) {Mycobacterium tuberculosis H37Rv (lab strain)}
2535Rv2540c, (MTCY159.16), len: 401 aa. aroF, similar to eg AROC_BACSU P31104 chorismate synthase (368 aa), fasta scores, opt: 1134, E(): 0, (48.9% identity in 358 aa overlap); contains PS00788 Chorismate synthase signature 2 (aroF) {Mycobacterium tuberculosis H37Rv (lab strain)}
2536Rv2541hypothetical protein Rv2541 {Mycobacterium tuberculosis H37Rv (lab strain)}
2537Rv2542hypothetical protein Rv2542 {Mycobacterium tuberculosis H37Rv (lab strain)}
2538Rv2543, (MTCY159.13c), len: 219 aa. Probable lipoprotein highly similar to MTCY159.12c (87.2% identity in 218aa overlap), contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site (lppA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2539Rv2544, (MTCY159.12c), len: 220 aa. Probable lipoprotein, highly similar to MTCY159.13c (87.2% identity in 218aa overlap), TBparse score is 0.924; contains PS00013 Prokaryotic membrane lipoprotein lipid attachment site (lppB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2540Rv2545hypothetical protein Rv2545 {Mycobacterium tuberculosis H37Rv (lab strain)}
2541Rv2546hypothetical protein Rv2546 {Mycobacterium tuberculosis H37Rv (lab strain)}
2542Rv2547hypothetical protein Rv2547 {Mycobacterium tuberculosis H37Rv (lab strain)}
2543Rv2548hypothetical protein Rv2548 {Mycobacterium tuberculosis H37Rv (lab strain)}
2544Rv2549chypothetical protein Rv2549c {Mycobacterium tuberculosis H37Rv (lab strain)}
2545Rv2550chypothetical protein Rv2550c {Mycobacterium tuberculosis H37Rv (lab strain)}
2546Rv2551chypothetical protein Rv2551c {Mycobacterium tuberculosis H37Rv (lab strain)}
2547Rv2552c, (MTCY159.04), len: 269 aa. Probable aroE, shikimate 5-dehydrogenas, similar to eg AROE_ECOLI P15770 shikimate 5-dehydrogenase (272 aa), fasta scores, opt: 230, E(): 7.7e-08, (29.5% identity in 251 aa overlap) (aroE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2548Rv2553chypothetical protein Rv2553c {Mycobacterium tuberculosis H37Rv (lab strain)}
2549Rv2554chypothetical protein Rv2554c {Mycobacterium tuberculosis H37Rv (lab strain)}
2550Rv2555c, (MTCY318.01c-MTCY159.01), len: 904. alaS,alanyl-trna synthetase, similar to many eg. SYA_THIFE Q56273 alanyl-trna synthetase (ec 6.1.1.7) (877 aa), fasta scores; opt: 635 z-score: 2153.3 E(): 0, 43.5% identity in 751aa overlap (alaS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2551Rv2556chypothetical protein Rv2556c {Mycobacterium tuberculosis H37Rv (lab strain)}
2552Rv2557hypothetical protein Rv2557 {Mycobacterium tuberculosis H37Rv (lab strain)}
2553Rv2558hypothetical protein Rv2558 {Mycobacterium tuberculosis H37Rv (lab strain)}
2554Rv2559chypothetical protein Rv2559c {Mycobacterium tuberculosis H37Rv (lab strain)}
2555Rv2560hypothetical protein Rv2560 {Mycobacterium tuberculosis H37Rv (lab strain)}
2556Rv2561hypothetical protein Rv2561 {Mycobacterium tuberculosis H37Rv (lab strain)}
2557Rv2562hypothetical protein Rv2562 {Mycobacterium tuberculosis H37Rv (lab strain)}
2558Rv2563hypothetical protein Rv2563 {Mycobacterium tuberculosis H37Rv (lab strain)}
2559Rv2564, (MTCY9C4.04c), len: 330.glnQ, Probable atp-binding transport protein, highly similar to gp|AL021428|MTV030_17 Mycobacterium tuberculosis (330 aa) fasta scores:opt: 1782 z-score: 2078.1 E(): 0; 83.6% identity in 330 aa overlap; also some similarity to G1 (glnQ) {Mycobacterium tuberculosis H37Rv (lab strain)}
2560Rv2565hypothetical protein Rv2565 {Mycobacterium tuberculosis H37Rv (lab strain)}
2561Rv2566hypothetical protein Rv2566 {Mycobacterium tuberculosis H37Rv (lab strain)}
2562Rv2567hypothetical protein Rv2567 {Mycobacterium tuberculosis H37Rv (lab strain)}
2563Rv2568chypothetical protein Rv2568c {Mycobacterium tuberculosis H37Rv (lab strain)}
2564Rv2569chypothetical protein Rv2569c {Mycobacterium tuberculosis H37Rv (lab strain)}
2565Rv2570hypothetical protein Rv2570 {Mycobacterium tuberculosis H37Rv (lab strain)}
2566Rv2571chypothetical protein Rv2571c {Mycobacterium tuberculosis H37Rv (lab strain)}
2567Rv2572c, (MTCY227.29), len: 596. aspS, aspartyl-trna synthetase, highly similar to SYD_MYCLE P36429 (589 aa) FASTA scores, opt: 3534, z-, len: 300, highly similar to LINB_PSEPA P51698 score: 4184.0, E(): 0, (87.8% identity in 592 aa overlap); contains PS00179 Am (aspS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2568Rv2573hypothetical protein Rv2573 {Mycobacterium tuberculosis H37Rv (lab strain)}
2569Rv2574hypothetical protein Rv2574 {Mycobacterium tuberculosis H37Rv (lab strain)}
2570Rv2575hypothetical protein Rv2575 {Mycobacterium tuberculosis H37Rv (lab strain)}
2571Rv2576chypothetical protein Rv2576c {Mycobacterium tuberculosis H37Rv (lab strain)}
2572Rv2577hypothetical protein Rv2577 {Mycobacterium tuberculosis H37Rv (lab strain)}
2573Rv2578chypothetical protein Rv2578c {Mycobacterium tuberculosis H37Rv (lab strain)}
2574Rv2579, (MTCY227.22c), len: 300, highly similar to LINB_PSEPA P51698 1,3,4,6-tetrachloro-1,4-cyclohexadiene hydrolase (295 aa) FASTA scores, opt: 1475, z-score: 1640.2, E(): 0, (69.2% identity in 295 aa overlap), some similarityto MTCY339.14c, 30.8% identity in (linB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2575Rv2580c, (MTCY227.21), len: 423. hisS, histidyl-trna synthetase, highly similar to SYH_MYCLE P46696 histidyl-trna synthetase (427 aa), FASTA scores, opt: 2375, z-score: 2558.1, E(): 0, 84.9% identity in 424 aa overlap; contains PS00017 ATP/GTP-binding site motif (hisS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2576Rv2581chypothetical protein Rv2581c {Mycobacterium tuberculosis H37Rv (lab strain)}
2577Rv2582, (MTCY227.19c), len: 308. Probable cyclophilin, ppiB, highly similar to CYPH_MYCLE P46697 probable peptidyl-prolyl cis-trans isomerase (295 aa) FASTA scores, opt: 1423, z-score: 1371.2, E(): 0, (72.2% identity in 295 aa overlap) (ppiB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2578Rv2583c, (MTCY227.18), len: 790, relA, highly similar to sp|Q49640|RELA_MYCLE PUTATIVE GTP PYROPHOSPHOKINASE (E (787 aa) fasta score: opt: 4834 z-score: 5560.4 E(): 0;93.4% identity in 790 aa overlap (relA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2579Rv2584c, (MTCY227.17), len: 223. Probable apt, adenine phosphoribosyltransferase, similar to adenine phosphoribosyltransferases eg APT_ECOLI P07672 (183 aa) FASTA scores, opt: 393 z-score: 456.2 E(): 1.9e-18, (42.6% identity in 162 aa overlap), nearest initiatio (apt) {Mycobacterium tuberculosis H37Rv (lab strain)}
2580Rv2585chypothetical protein Rv2585c {Mycobacterium tuberculosis H37Rv (lab strain)}
2581Rv2586c, MTCY227.15, len: 442, probable secF, highly similar to SECF_MYCLE P38386 protein-export membrane protein secf. (394 aa) FASTA scores, opt: 1831, z-score: 2011.5, E(): 0, (75.4% identity in 398 aa overlap) (secF) {Mycobacterium tuberculosis H37Rv (lab strain)}
2582Rv2587c, (MTCY227.14), len: 573. Probable secD, highly similar to SECD_MYCLE P38387 protein-export membrane protein secd. (701 aa) FASTA scores, opt: 2462, z-score: 1738.2, E(): 0, (79.8% identity in 496 aa overlap) (secD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2583Rv2588chypothetical protein Rv2588c {Mycobacterium tuberculosis H37Rv (lab strain)}
2584Rv2589, (MTCY227.12c), len: 449. Probable gabT, highly similar to GABT_MYCLE P40829 4-aminobutyrate aminotransferase (446 aa) FASTA scores, opt: 2468, z-score: 2761.7, E(): 0, (83.7% identity in 449 aa overlap); contains PS00600Aminotransferases class-III pyrid (gabT) {Mycobacterium tuberculosis H37Rv (lab strain)}
2585Rv2590, (MTCY227.11c), len: 1168. fadD9, Acyl-CoA Synthetase. N-terminal 700 residues similar to long chain fatty acid ligase; C-terminus to polyketide synthases; contains PS00455 Putative AMP-binding domain signature, PS00061 Short-chain alcohol dehydrogenase (fadD9) {Mycobacterium tuberculosis H37Rv (lab strain)}
2586Rv2591, (MTCY227.10c), len: 543. Member of M. tuberculosis, PE family, PGRS subfamily; contains PS00583 pfkB family of carbohydrate kinases signature 1, highly similar to others e.g. MTCY130.10c, MTCY49.39c and MTCY39.36c (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2587Rv2592c, (MTCY227.09), len: 344 aa. Holliday junction binding protein ruvB, RUVB_MYCLE P40833 probable holliday junction dna helicase (369 aa) FASTA scores, opt: 1929, z-score: 2176.5 E(): 0, (94.4% identity in 321 aa overlap); contains PS00017 ATP/GTP-binding s (ruvB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2588Rv2593c, (MTCY227.08), len: 196. Holliday junction binding protein ruvA, highly similar to RUVA_MYCLE P40832 probable holliday junction dna helicase (203 aa) FASTA scores, opt: 923, z-score: 1063.6, E(): 0, (76.8% identity in 203 aa overlap) (ruvA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2589Rv2594c, (MTCY227.07), len: 188. Holliday junction resolvase, highly similar to RUVC_MYCLE P40834 probable crossover junction endodeoxyribonuclease ruvC (188 aa) FASTA scores, opt: 984, z-score: 1157.8, E(): 0, (81.0% identity in 184 aa overlap) (ruvC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2590Rv2595hypothetical protein Rv2595 {Mycobacterium tuberculosis H37Rv (lab strain)}
2591Rv2596hypothetical protein Rv2596 {Mycobacterium tuberculosis H37Rv (lab strain)}
2592Rv2597hypothetical protein Rv2597 {Mycobacterium tuberculosis H37Rv (lab strain)}
2593Rv2598hypothetical protein Rv2598 {Mycobacterium tuberculosis H37Rv (lab strain)}
2594Rv2599hypothetical protein Rv2599 {Mycobacterium tuberculosis H37Rv (lab strain)}
2595Rv2600hypothetical protein Rv2600 {Mycobacterium tuberculosis H37Rv (lab strain)}
2596Rv2602hypothetical protein Rv2602 {Mycobacterium tuberculosis H37Rv (lab strain)}
2597Rv2603chypothetical protein Rv2603c {Mycobacterium tuberculosis H37Rv (lab strain)}
2598Rv2604chypothetical protein Rv2604c {Mycobacterium tuberculosis H37Rv (lab strain)}
2599Rv2605c, (MTCY01A10.28), len: 281 aa. tesB2, similar eg to TESB_ECOLI P23911 acyl-coa thioesterase ii (285 aa), fasta scores, opt: 487, E(): 1e-25, (41.9% identity in 277 aa overlap), also MTCY01B2.10 (300 aa) opt: 425 z-score: 482.2 E(): 1.1e-21, (34.9% identit (tesB2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2600Rv2606chypothetical protein Rv2606c {Mycobacterium tuberculosis H37Rv (lab strain)}
2601Rv2607, (MTCY01A10.26c), len: 224 aa. pdxH, similarto PDXH_ECOLI P28225 pyridoxamine 5-phosphate oxidase (217aa), fasta scores, opt: 533, E(): 1.6e-28, (40.3% identityin 216 aa overlap) (pdxH) {Mycobacterium tuberculosis H37Rv (lab strain)}
2602Rv2608, (MTCY01A10.25c), len: 580 aa. Unknown, belongs to the M. tuberculosis PPE family, similar to eg YZ06_MYCTU Q10540 hypothetical 43.6 kd protein cy31.06c (443 aa),fasta scores, opt: 903, E(): 0, (54.8% identity in 303 aa overlap) (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2603Rv2609chypothetical protein Rv2609c {Mycobacterium tuberculosis H37Rv (lab strain)}
2604Rv2610chypothetical protein Rv2610c {Mycobacterium tuberculosis H37Rv (lab strain)}
2605Rv2611chypothetical protein Rv2611c {Mycobacterium tuberculosis H37Rv (lab strain)}
2606Rv2612c, (MTCY01A10.21), len: 217 aa. Probable pgsAsimilarity to CDP-diacylglycerol--glycerol-3-phosphate phosphatidyltransferases, equivalent to Z96801|MLCL581_10 Mycobacterium leprae cosmid L581; (239 aa) fasta scores: opt: 1141 z-score: 1451.6 E(): 0; 79.3% i (pgsA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2607Rv2613chypothetical protein Rv2613c {Mycobacterium tuberculosis H37Rv (lab strain)}
2608Rv2614c, (MTCY01A10.20), len: 692 aa. thrS, similarto SYT_ECOLI P00955 threonyl-trna synthetase (642 aa), fasta scores, opt: 946, E(): 0, (40.7% identity in 612 aa overlap); contains PS00339 Aminoacyl-transfer RNA synthetases class-II signature 2 (thrS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2609Rv2615c, (MTCY01A10.19), len: 461 aa. Member of M. tuberculosis gly-, ala-, asn-rich PE protein family, pgrs subfamily (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2610Rv2616hypothetical protein Rv2616 {Mycobacterium tuberculosis H37Rv (lab strain)}
2611Rv2617chypothetical protein Rv2617c {Mycobacterium tuberculosis H37Rv (lab strain)}
2612Rv2618hypothetical protein Rv2618 {Mycobacterium tuberculosis H37Rv (lab strain)}
2613Rv2619chypothetical protein Rv2619c {Mycobacterium tuberculosis H37Rv (lab strain)}
2614Rv2620chypothetical protein Rv2620c {Mycobacterium tuberculosis H37Rv (lab strain)}
2615Rv2621chypothetical protein Rv2621c {Mycobacterium tuberculosis H37Rv (lab strain)}
2616Rv2622hypothetical protein Rv2622 {Mycobacterium tuberculosis H37Rv (lab strain)}
2617Rv2623hypothetical protein Rv2623 {Mycobacterium tuberculosis H37Rv (lab strain)}
2618Rv2624chypothetical protein Rv2624c {Mycobacterium tuberculosis H37Rv (lab strain)}
2619Rv2625chypothetical protein Rv2625c {Mycobacterium tuberculosis H37Rv (lab strain)}
2620Rv2626chypothetical protein Rv2626c {Mycobacterium tuberculosis H37Rv (lab strain)}
2621Rv2627chypothetical protein Rv2627c {Mycobacterium tuberculosis H37Rv (lab strain)}
2622Rv2628hypothetical protein Rv2628 {Mycobacterium tuberculosis H37Rv (lab strain)}
2623Rv2629hypothetical protein Rv2629 {Mycobacterium tuberculosis H37Rv (lab strain)}
2624Rv2630hypothetical protein Rv2630 {Mycobacterium tuberculosis H37Rv (lab strain)}
2625Rv2631hypothetical protein Rv2631 {Mycobacterium tuberculosis H37Rv (lab strain)}
2626Rv2632chypothetical protein Rv2632c {Mycobacterium tuberculosis H37Rv (lab strain)}
2627Rv2633chypothetical protein Rv2633c {Mycobacterium tuberculosis H37Rv (lab strain)}
2628Rv2634c, (MTCY441.04c), len: 778. Member of glycinerich PE protein family, PGRS subfamily (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2629Rv2635hypothetical protein Rv2635 {Mycobacterium tuberculosis H37Rv (lab strain)}
2630Rv2636hypothetical protein Rv2636 {Mycobacterium tuberculosis H37Rv (lab strain)}
2631Rv2637, (MTCY441.07), len: 218. dedA, equivalent to M. leprae dedA homolog Z96801|MLCL58118 MLCL581 NID: g2193890 - Mycobacteria (214 aa) opt: 1160; E(): 0; 82.8% identity in 209 aa overlap) (dedA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2632Rv2638hypothetical protein Rv2638 {Mycobacterium tuberculosis H37Rv (lab strain)}
2633Rv2639chypothetical protein Rv2639c {Mycobacterium tuberculosis H37Rv (lab strain)}
2634Rv2640chypothetical protein Rv2640c {Mycobacterium tuberculosis H37Rv (lab strain)}
2635Rv2641hypothetical protein Rv2641 {Mycobacterium tuberculosis H37Rv (lab strain)}
2636Rv2642hypothetical protein Rv2642 {Mycobacterium tuberculosis H37Rv (lab strain)}
2637Rv2643, (MTCY441.13), len: 498. arsC, potential membrane protein, similar to conserved hypothetical proteins e.g. YQCL_BACSU P45946 hypothetical 38.3 kd protein in cwla-(346 aa), fasta scores, opt: 1173, E(): 0, (50.4% identityin 343 aa overlap). C-terminal par (arsC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2638Rv2644chypothetical protein Rv2644c {Mycobacterium tuberculosis H37Rv (lab strain)}
2639Rv2645hypothetical protein Rv2645 {Mycobacterium tuberculosis H37Rv (lab strain)}
2640Rv2646hypothetical protein Rv2646 {Mycobacterium tuberculosis H37Rv (lab strain)}
2641Rv2647hypothetical protein Rv2647 {Mycobacterium tuberculosis H37Rv (lab strain)}
2642Rv2648hypothetical protein Rv2648 {Mycobacterium tuberculosis H37Rv (lab strain)}
2643Rv2649hypothetical protein Rv2649 {Mycobacterium tuberculosis H37Rv (lab strain)}
2644Rv2650chypothetical protein Rv2650c {Mycobacterium tuberculosis H37Rv (lab strain)}
2645Rv2651chypothetical protein Rv2651c {Mycobacterium tuberculosis H37Rv (lab strain)}
2646Rv2652chypothetical protein Rv2652c {Mycobacterium tuberculosis H37Rv (lab strain)}
2647Rv2653chypothetical protein Rv2653c {Mycobacterium tuberculosis H37Rv (lab strain)}
2648Rv2654chypothetical protein Rv2654c {Mycobacterium tuberculosis H37Rv (lab strain)}
2649Rv2655chypothetical protein Rv2655c {Mycobacterium tuberculosis H37Rv (lab strain)}
2650Rv2656chypothetical protein Rv2656c {Mycobacterium tuberculosis H37Rv (lab strain)}
2651Rv2657chypothetical protein Rv2657c {Mycobacterium tuberculosis H37Rv (lab strain)}
2652Rv2658chypothetical protein Rv2658c {Mycobacterium tuberculosis H37Rv (lab strain)}
2653Rv2659chypothetical protein Rv2659c {Mycobacterium tuberculosis H37Rv (lab strain)}
2654Rv2660chypothetical protein Rv2660c {Mycobacterium tuberculosis H37Rv (lab strain)}
2655Rv2661chypothetical protein Rv2661c {Mycobacterium tuberculosis H37Rv (lab strain)}
2656Rv2662hypothetical protein Rv2662 {Mycobacterium tuberculosis H37Rv (lab strain)}
2657Rv2663hypothetical protein Rv2663 {Mycobacterium tuberculosis H37Rv (lab strain)}
2658Rv2664hypothetical protein Rv2664 {Mycobacterium tuberculosis H37Rv (lab strain)}
2659Rv2665hypothetical protein Rv2665 {Mycobacterium tuberculosis H37Rv (lab strain)}
2660Rv2666hypothetical protein Rv2666 {Mycobacterium tuberculosis H37Rv (lab strain)}
2661Rv2667, (MTCY441.36), len: 252. clpX, similar to P24428|CLPC_MYCLE PROBABLE ATP-DEPENDENT CLP PROTE (649 aa).FASTA score: opt: 307, E(): 5.4e-12 (38.6% identity in 158aa overlap); MTCY7H7B26 NID: g2113954 - Mycobac (848 aa)opt: 307 E(): 6.8e-12; (38.6% identity (clpX) {Mycobacterium tuberculosis H37Rv (lab strain)}
2662Rv2668hypothetical protein Rv2668 {Mycobacterium tuberculosis H37Rv (lab strain)}
2663Rv2669hypothetical protein Rv2669 {Mycobacterium tuberculosis H37Rv (lab strain)}
2664Rv2670chypothetical protein Rv2670c {Mycobacterium tuberculosis H37Rv (lab strain)}
2665Rv2671, (MTCY441.40), len: 258. Possible ribD, verysimilar to hypothetical M. leprae protein MLCB1351.23. FASTA score: Z95117|MLCB1351.23NID: g2198498 - Mycobac (268 aa)opt: 1211 E(): 0; (72.9% identity in 251 aa overlap), similar to ribD, RIBD_ECOLI P25539 rib (ribD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2666Rv2672hypothetical protein Rv2672 {Mycobacterium tuberculosis H37Rv (lab strain)}
2667Rv2673hypothetical protein Rv2673 {Mycobacterium tuberculosis H37Rv (lab strain)}
2668Rv2674hypothetical protein Rv2674 {Mycobacterium tuberculosis H37Rv (lab strain)}
2669Rv2675chypothetical protein Rv2675c {Mycobacterium tuberculosis H37Rv (lab strain)}
2670Rv2676chypothetical protein Rv2676c {Mycobacterium tuberculosis H37Rv (lab strain)}
2671Rv2677c, (MTV010.01c), len: 425. Probable hemY, protoporphyrinogen oxidase, similar to several, closest to M.leprae enzyme (451 aa) but shorter than other other bacterial enzymes( 470). FASTA scores; sptr|Q50008|Q50008 HEMY (451 aa) opt: 2096 z-score: 2276.8 E() (hemY) {Mycobacterium tuberculosis H37Rv (lab strain)}
2672Rv2678c, (MTV010.02c), len: 357. hemE. Probable uroporphyrinogen decarboxylase (EC 4.1.1.37), similar to many.Best with M. leprae enzyme (except at N-terminus) but startchosen on basis of similarity to B. subtilis hemE. ContainsPS00907 Uroporphyrinogen decarboxy (hemE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2673Rv2679, (MTV010.03), len: 276. echA15, Probable Enoyl-CoA hydratase, similar to many. Closest to one from M. leprae (P53526) but also similar to M. tuberculosis enzymes like MTCI65.09c (Z95584). Contains PS00166 Enoyl-CoA hydratase/isomerase signature. FASTA sc (echA15) {Mycobacterium tuberculosis H37Rv (lab strain)}
2674Rv2680hypothetical protein Rv2680 {Mycobacterium tuberculosis H37Rv (lab strain)}
2675Rv2681hypothetical protein Rv2681 {Mycobacterium tuberculosis H37Rv (lab strain)}
2676Rv2682c, (MTCY05A6.03c), len: 638. dxs, PROBABLE 1-DEOXYXYLULOSE-5-PHOSPHATE SYNTHASE (DXP SYNTHASE)unknown but highly similar to M. leprae G699189 TktB, similar to transketolases (EC 2.2.1.1). FASTA best: G699189 TKTB. opt: 3635; E(): 0; 86.4% identity in 632 a (dxs) {Mycobacterium tuberculosis H37Rv (lab strain)}
2677Rv2683hypothetical protein Rv2683 {Mycobacterium tuberculosis H37Rv (lab strain)}
2678Rv2684, (MTCY05A6.05), len: 429. Function: arsA, corresponds to antigen 45 of M. leprae, a transmembrane protein related to arsenical pumps. FASTA best: AG45_MYCLE P46838 46 kd membrane protein (429 aa) opt: 2060; E(): 0; 73.8% identity in 428 aa overlap. Highl (arsA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2679Rv2685, (MTCY05A6.06), len: 428. arsB, Function: unknown membrane protein very similar to M. leprae antigen 45(P46838) and MTCY05A6.05; related to arsenical pumps. FASTA best: AG45_MYCLE P46838 46 kd membrane protein (429 aa) opt: 2041; E(): 0; 74.0% identity i (arsB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2680Rv2686chypothetical protein Rv2686c {Mycobacterium tuberculosis H37Rv (lab strain)}
2681Rv2687chypothetical protein Rv2687c {Mycobacterium tuberculosis H37Rv (lab strain)}
2682Rv2688chypothetical protein Rv2688c {Mycobacterium tuberculosis H37Rv (lab strain)}
2683Rv2689chypothetical protein Rv2689c {Mycobacterium tuberculosis H37Rv (lab strain)}
2684Rv2690chypothetical protein Rv2690c {Mycobacterium tuberculosis H37Rv (lab strain)}
2685Rv2691, (MTCY05A6.12), len: 227. Function: probabletrkA, similar to Streptomyces coelicolor TrkA, and also toN-terminal half of trk system potassium uptake protein (e.g.P39448). FASTA best: AL021530|SC2E9_17 Streptomyces coelicolor (223 aa) opt: 781 z-score: 98 (trkA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2686Rv2692, (MTCY05A6.13), len: 220. Function: trkA2, putative potassium uptake protein but similar to both N- andC-terminal halves of trk system potassium uptake proteins and especially to S. coelicolor trkA, (e.g. G1220706) and tosome hypothetical B. subtilis pro (trkB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2687Rv2693chypothetical protein Rv2693c {Mycobacterium tuberculosis H37Rv (lab strain)}
2688Rv2694chypothetical protein Rv2694c {Mycobacterium tuberculosis H37Rv (lab strain)}
2689Rv2695hypothetical protein Rv2695 {Mycobacterium tuberculosis H37Rv (lab strain)}
2690Rv2696chypothetical protein Rv2696c {Mycobacterium tuberculosis H37Rv (lab strain)}
2691Rv2697c, (MTCY05A6.18c), len: 154. dut, deoxyuridine 5-triphosphate nucleotidohydrolase. Highly similar to M.leprae protein and also to other deoxyuridine 5-triphosphate nucleotidohydrolases (e.g. P43058). FASTA best: G699195COSMID B1764 opt: 932; E(): 0; 90.9% (dut) {Mycobacterium tuberculosis H37Rv (lab strain)}
2692Rv2698hypothetical protein Rv2698 {Mycobacterium tuberculosis H37Rv (lab strain)}
2693Rv2699chypothetical protein Rv2699c {Mycobacterium tuberculosis H37Rv (lab strain)}
2694Rv2700hypothetical protein Rv2700 {Mycobacterium tuberculosis H37Rv (lab strain)}
2695Rv2701c, (MTCY05A6.22c), len: 290. Function: suhB, probable extragenic suppressor protein SuhB, also similar to myo-inositol-1(or 4)-monophosphatase. Contains PS00630 Inositol monophosphatase family signatures 1 and 2 (PS00629,PS00630). FASTA best: SUHB_MYCLE P4 (suhB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2696Rv2702, (MTCY05A6.23), len: 265. Function: ppgK, probable polyphosphate glucokinase Q59568 POLYPHOSPHATE GLUCOKINASE (EC 2.7.1.63) (POLYPHOSPHATE-GLUCOSE PHOSPHOTRANSFERASE). FASTA best: G1172222 POLYPHOSPHATE GLUCOKINASE (EC 2.7.1.63) (265 aa) opt: 1721; E(): (ppgK) {Mycobacterium tuberculosis H37Rv (lab strain)}
2697Rv2703, (MTCY05A6.24), len: 528. Function: sigA, RNA polymerase sigma factor (formerly MysA, also known as rpoV). Contains sigma-70 family signatures 1 and 2 (PS00715, PS00716). FASTA best: G1171102 RNA POLYMERASE SIGMA FACTOR. (528 aa) opt: 3366; E(): 0; 100% (sigA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2698Rv2704hypothetical protein Rv2704 {Mycobacterium tuberculosis H37Rv (lab strain)}
2699Rv2705chypothetical protein Rv2705c {Mycobacterium tuberculosis H37Rv (lab strain)}
2700Rv2706chypothetical protein Rv2706c {Mycobacterium tuberculosis H37Rv (lab strain)}
2701Rv2707hypothetical protein Rv2707 {Mycobacterium tuberculosis H37Rv (lab strain)}
2702Rv2708chypothetical protein Rv2708c {Mycobacterium tuberculosis H37Rv (lab strain)}
2703Rv2709hypothetical protein Rv2709 {Mycobacterium tuberculosis H37Rv (lab strain)}
2704Rv2710, (MTCY05A6.31), len: 323. Function: sigB, RNA polymerase sigma factor (formerly MysB). Contains sigma-70 factors family signatures 1 and 2 (PS00715; PS00716)FASTA best: G1171103 (323 aa) opt: 2062; E(): 0; 100.0% identity in 323 aa overlap. Highly simila (sigB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2705Rv2711, (MTCY05A6.32), len: 230. Function: ideR, iron dependent repressor, IdeR, formerly known as DtxR. FASTAbest: G1171107 DIPTHERIA TOXIN REPRESSOR HOMOLOG (DTXR). 6/96 (230 aa)opt: 1494; E(): 0; 100.0% identity in 230 aa overlap. TBparse score is 0.876 (ideR) {Mycobacterium tuberculosis H37Rv (lab strain)}
2706Rv2712chypothetical protein Rv2712c {Mycobacterium tuberculosis H37Rv (lab strain)}
2707Rv2713hypothetical protein Rv2713 {Mycobacterium tuberculosis H37Rv (lab strain)}
2708Rv2714hypothetical protein Rv2714 {Mycobacterium tuberculosis H37Rv (lab strain)}
2709Rv2715hypothetical protein Rv2715 {Mycobacterium tuberculosis H37Rv (lab strain)}
2710Rv2716hypothetical protein Rv2716 {Mycobacterium tuberculosis H37Rv (lab strain)}
2711Rv2717chypothetical protein Rv2717c {Mycobacterium tuberculosis H37Rv (lab strain)}
2712Rv2718chypothetical protein Rv2718c {Mycobacterium tuberculosis H37Rv (lab strain)}
2713Rv2719chypothetical protein Rv2719c {Mycobacterium tuberculosis H37Rv (lab strain)}
2714Rv2720, (MTCY05A6.41), len: 217. Function: LexA repressor. FASTA results: G1016352 LEXA GENE opt:1404; E(): 0;100% identity in 217 aa overlap. TBparse score is 0.872 (lexA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2715Rv2721chypothetical protein Rv2721c {Mycobacterium tuberculosis H37Rv (lab strain)}
2716Rv2722hypothetical protein Rv2722 {Mycobacterium tuberculosis H37Rv (lab strain)}
2717Rv2723hypothetical protein Rv2723 {Mycobacterium tuberculosis H37Rv (lab strain)}
2718Rv2724c, (MTCY154.04c), len: 386.fadE20, Probable acyl-coa dehydrogenase, similar to many eg. ACDB_BACSU P45857 acyl-coa dehydrogenase (ec 1.3.99.-) (379 aa), fasta scores; opt: 854 z-score: 1212.7 E(): 0, 38.9% identity in 370aa overlap. Contains PS00073 Acyl-C (fadE20) {Mycobacterium tuberculosis H37Rv (lab strain)}
2719Rv2725c, (MTCY154.05c), len: 495; Probable HflX, GTP-binding protein, similar to HFLX_ECOLI P25519 gtp-bindingprotein hflx (426 aa), fasta scores; opt: 916 z-score: 537.9 E(): 5.1e-23, 40.1% identity in 414 aa overlap. ContainsPS00017 ATP/GTP-binding site motif (hflX) {Mycobacterium tuberculosis H37Rv (lab strain)}
2720Rv2726c, (MTCY154.06c), len: 289 aa. dapF, probablediaminopimelate epimerase, similar tomany eg. DAPF_SYNY3 P74667 diaminopimelate epimerase (ec 5.1.1.7) (279 aa), fastascores; opt: 251 z-score: 440.1 E(): 1.4e-17Smith-Watermanscore: 396; 34.2% identity in 295 a (dapF) {Mycobacterium tuberculosis H37Rv (lab strain)}
2721Rv2727c, (MTCY154.07c), len: 314. miaA, probable trna delta(2)-isopentenylpyrophosphate transferase, len: 314 aa; similar to many eg. MIAA_ECOLI P16384 trna delta(2)-isopentenylpyrophosphate transferase (316 aa), fasta scores; opt: 565 z-score: 528.6 E(): 1.7e-2 (miaA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2722Rv2728chypothetical protein Rv2728c {Mycobacterium tuberculosis H37Rv (lab strain)}
2723Rv2729chypothetical protein Rv2729c {Mycobacterium tuberculosis H37Rv (lab strain)}
2724Rv2730hypothetical protein Rv2730 {Mycobacterium tuberculosis H37Rv (lab strain)}
2725Rv2731hypothetical protein Rv2731 {Mycobacterium tuberculosis H37Rv (lab strain)}
2726Rv2732chypothetical protein Rv2732c {Mycobacterium tuberculosis H37Rv (lab strain)}
2727Rv2733chypothetical protein Rv2733c {Mycobacterium tuberculosis H37Rv (lab strain)}
2728Rv2734hypothetical protein Rv2734 {Mycobacterium tuberculosis H37Rv (lab strain)}
2729Rv2735chypothetical protein Rv2735c {Mycobacterium tuberculosis H37Rv (lab strain)}
2730Rv2736c, (MTV002.01c), len: 174 aa. recX, similar to eg. RECX_PSEAE P37860 regulatory protein recx from Pseudomonas aeruginosa (153 aa), fasta scores; opt: 161 z-score: 257.2 E(): 3.6e-07, 30.7% identity in 137 aa overlap. Overlaps and extends CDS from ovelappin (recX) {Mycobacterium tuberculosis H37Rv (lab strain)}
2731Rv2737c, (MTV002.02c), len: 790 aa. recA, identicalto RECA_MYCTU P26345 reca protein (790 aa). Contains self-splicing protein element (intein) from 2294 to 969 (c), similar to intein II from TR:E332317 (EMBL:Y13030) DNA-directedDNA polymerase (EC 2.7.7.7) from T (recA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2732Rv2738chypothetical protein Rv2738c {Mycobacterium tuberculosis H37Rv (lab strain)}
2733Rv2739chypothetical protein Rv2739c {Mycobacterium tuberculosis H37Rv (lab strain)}
2734Rv2740hypothetical protein Rv2740 {Mycobacterium tuberculosis H37Rv (lab strain)}
2735Rv2741, (MTV002.06), len: 525 aa; Member of M. tuberculosis PE_ PGRS subfamily, similar to many eg. Y0DP_MYCTUQ50615 hypothetical glycine-rich 40.8 kd protein (498 aa),fasta scores; opt: 1923 z-score: 844.3 E(): 0, 61.6% identity in 536 aa overlap (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2736Rv2742chypothetical protein Rv2742c {Mycobacterium tuberculosis H37Rv (lab strain)}
2737Rv2743chypothetical protein Rv2743c {Mycobacterium tuberculosis H37Rv (lab strain)}
2738Rv2744c, (MTV002.09c), len: 270 aa. 35-kd antigen; identical to 35KD_MYCTU P31511 35 kd protein (270 aa); alsosimilar to a Synechocystis hypothetical protein TR:Q55707 (EMBL:D64002) SLL0617 (267 aa), fasta scores; opt: 155 z-score: 231.0 E(): 1e-05, 23.4% identi (35kd_ag) {Mycobacterium tuberculosis H37Rv (lab strain)}
2739Rv2745chypothetical protein Rv2745c {Mycobacterium tuberculosis H37Rv (lab strain)}
2740Rv2746c, (MTV002.11c), len: 209 aa. pgsA2, PGP synthase; similar to many eg. PGSA_ECOLI P06978 cdp-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase (181 aa), fasta scores; opt: 322 z-score: 419.3 E(): 3.3e-16, 34.4% identity in 180 aa overlap. Cont (pgsA3) {Mycobacterium tuberculosis H37Rv (lab strain)}
2741Rv2747hypothetical protein Rv2747 {Mycobacterium tuberculosis H37Rv (lab strain)}
2742Rv2748c, (MTV002.13c), len: 883 aa. Possible ftsK, member of the spoIIIE/ftsK family; similar in C-terminal half to SP3E_BACSU P21458 stage iii sporulation protein e (787 aa), fasta scores; opt: 1294 z-score: 1488.5 E(): 0, 50.9% identity in 485 aa overlap, and (ftsK) {Mycobacterium tuberculosis H37Rv (lab strain)}
2743Rv2749hypothetical protein Rv2749 {Mycobacterium tuberculosis H37Rv (lab strain)}
2744Rv2750hypothetical protein Rv2750 {Mycobacterium tuberculosis H37Rv (lab strain)}
2745Rv2751hypothetical protein Rv2751 {Mycobacterium tuberculosis H37Rv (lab strain)}
2746Rv2752chypothetical protein Rv2752c {Mycobacterium tuberculosis H37Rv (lab strain)}
2747Rv2753c, (MTV002.18c), len: 300 aa. dapA, dihydrodipicolinate synthase; similar to many eg. DAPA_ECOLI P05640 dihydrodipicolinate synthase (ec 4.2.1.52) (292 aa), fasta scores; opt: 515 z-score: 735.8 E(): 0, 33.8% identity in 287 aa overlap. Contains PS00665 an (dapA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2748Rv2754chypothetical protein Rv2754c {Mycobacterium tuberculosis H37Rv (lab strain)}
2749Rv2755c, (MTV002.20c), len: 91 aa. hsdS, possible type I restriction/modification system specificity determinant (S protein), similar to the N-terminus of hsdS from Klebsiella pneumoniae TR:G2408222 EMBL:KPU93843 hsdS (439 aa), fasta scores; opt: 303 z-score: 53 (hsdS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2750Rv2756c, (MTV002.21c), len: 540 aa. hsdM, type I restriction/modification system DNA methylase (M protein); similar to many eg. Klebsiella pneumoniae TR:G2408224 (EMBL:KPU93843) hsdM (539 aa), fasta scores; opt: 1267 z-score: 1978.5 E(): 0, 45.9% identity in 549 (hsdM) {Mycobacterium tuberculosis H37Rv (lab strain)}
2751Rv2757chypothetical protein Rv2757c {Mycobacterium tuberculosis H37Rv (lab strain)}
2752Rv2758chypothetical protein Rv2758c {Mycobacterium tuberculosis H37Rv (lab strain)}
2753Rv2759chypothetical protein Rv2759c {Mycobacterium tuberculosis H37Rv (lab strain)}
2754Rv2760chypothetical protein Rv2760c {Mycobacterium tuberculosis H37Rv (lab strain)}
2755Rv2761chypothetical protein Rv2761c {Mycobacterium tuberculosis H37Rv (lab strain)}
2756Rv2762chypothetical protein Rv2762c {Mycobacterium tuberculosis H37Rv (lab strain)}
2757Rv2763c, (MTV002.28c), len: 159 aa. dfrA, dihydrofolate reductase; similar to many eg. DYR_BACSU P11045 dihydrofolate reductase (ec 1.5.1.3) (168 aa), fasta scores; opt:340 z-score: 464.7 E(): 9.9e-19, 39.0% identity in 146 aa overlap. Contains PS00075 Dihydrofo (dfrA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2758Rv2764c, (MTV002.29c), len: 263 aa. thyA, thymidylate synthase; highly similar to many eg. TYSY_ECOLI P00470 thymidylate synthase (ec 2.1.1.45) (264 aa), fasta scores; opt: 1309 z-score: 1937.5 E(): 0, 66.7% identity in 261 aa overlap. Contains PS00091 Thymidyla (thyA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2759Rv2765hypothetical protein Rv2765 {Mycobacterium tuberculosis H37Rv (lab strain)}
2760Rv2766c, (MTV002.31c), len: 260 aa. fabG5, probable 3-oxoacyl-[acyl-carrier protein]; Similar to many. fasta scores; sp|P51831|FABG_BACSU 3-OXOACYL-[ACYL-CARRIER PROTEIN] (246 aa) opt: 504 z-score: 639.3 E(): 4e-28; 37.2% identity in 247 aa overlap. Also similar (fabG5) {Mycobacterium tuberculosis H37Rv (lab strain)}
2761Rv2767chypothetical protein Rv2767c {Mycobacterium tuberculosis H37Rv (lab strain)}
2762Rv2768c, (MTV002.33c), len: 394 aa. Member of the PPE family of conserved M. tuberculosis hypothetical proteins, ; most similar to TR:P96362 (EMBL:Z92539) MTCY10G2.10 (391 aa), fasta scores; opt: 1721 z-score: 1639.4 E(): 0, 70.4% identity in 398 aa overlap (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2763Rv2769c, (MTV002.34c), len: 275 aa. Member of the PE family; similar to the N-terminus of the PE family of M. tuberculosis hypothetical proteins eg. TR:P96361 (EMBL:Z92539) MTCY10G2.09 (275 aa), fasta scores; opt: 1111 z-score:894.2 E(): 0, 68.6% identity in 283 (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2764Rv2770c, (MTV002.35c), len: 402 aa. Member of the PPE family of conserved M. tuberculosis hypothetical proteins; most similar to TR:P96362 (EMBL:Z92539) MTCY10G2.10 (391aa), fasta scores; opt: 1010 z-score: 1317.7 E(): 0, 55.9%identity in 395 aa overlap (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2765Rv2771chypothetical protein Rv2771c {Mycobacterium tuberculosis H37Rv (lab strain)}
2766Rv2772chypothetical protein Rv2772c {Mycobacterium tuberculosis H37Rv (lab strain)}
2767Rv2773c, (MTV002.38c), len: 245 aa. dapB, dihydrodipicolinate reductase; identical to DAPB_MYCTU P72024 dihydrodipicolinate reductase (ec 1.3.1.26) (245 aa) (dapB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2768Rv2774chypothetical protein Rv2774c {Mycobacterium tuberculosis H37Rv (lab strain)}
2769Rv2775hypothetical protein Rv2775 {Mycobacterium tuberculosis H37Rv (lab strain)}
2770Rv2776chypothetical protein Rv2776c {Mycobacterium tuberculosis H37Rv (lab strain)}
2771Rv2777chypothetical protein Rv2777c {Mycobacterium tuberculosis H37Rv (lab strain)}
2772Rv2778chypothetical protein Rv2778c {Mycobacterium tuberculosis H37Rv (lab strain)}
2773Rv2779chypothetical protein Rv2779c {Mycobacterium tuberculosis H37Rv (lab strain)}
2774Rv2780, (MTV002.45), len: 371 aa. ald, L-alanine dehydrogenase (40 kd antigen); almost identical to DHA_MYCTU P30234 alanine dehydrogenase (ec 1.4.1.1) (40 kd antigen) (373 aa) 99.5% identity in 373 aa overlap. Contains PS00836 and PS00837 Alanine dehydrogenase (ald) {Mycobacterium tuberculosis H37Rv (lab strain)}
2775Rv2781chypothetical protein Rv2781c {Mycobacterium tuberculosis H37Rv (lab strain)}
2776Rv2782c, (MTV002.47c), len: 438. pepR, probable protease/peptidase; similar to many eg. YMXG_BACSU (EMBL:U27560) Q04805 hypothetical processing protease (409 aa), fasta scores; opt: 1014 z-score: 1087.9 E(): 0, 38.3% identity in413 aa overlap. Contains PS00143 I (pepR) {Mycobacterium tuberculosis H37Rv (lab strain)}
2777Rv2783c, (MTV002.48c), len: 752 aa. gpsI, probable guanosine pentaphosphate synthetase and polyribonucleotide nucleotidyltransferase,; highly similar to Streptomyces antibioticus TR:Q53597 (EMBL:U19858) guanosine pentaphosphate synthetase, gpsI (740 aa), fasta s (gpsI) {Mycobacterium tuberculosis H37Rv (lab strain)}
2778Rv2784c, (MTV002.49c), len: 171 aa. Unknown, contains signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site (lppU) {Mycobacterium tuberculosis H37Rv (lab strain)}
2779Rv2785c, (MTV002.50c), len: 89 aa. rpsO, 30s ribosomal protein S15; highly similar to many eg. RS15_ECOLI P02371 30s ribosomal protein s15 (88 aa), fasta scores; opt: 295 z-score: 524.7 E(): 4.5e-22, 52.3% identity in 88 aa overlap. Contains PS00362 Ribosomal pr (rpsO) {Mycobacterium tuberculosis H37Rv (lab strain)}
2780Rv2786c, (MTV002.51c), len: 331 aa. ribF, riboflavin kinase; similar to many eg. RIBF_ECOLI P08391 riboflavin kinase (ec 2.7.1.26) (313 aa), fasta scores; opt: 517 z-score: 812.5 E(): 0, 35.9% identity in 306 aa overlap (ribF) {Mycobacterium tuberculosis H37Rv (lab strain)}
2781Rv2787hypothetical protein Rv2787 {Mycobacterium tuberculosis H37Rv (lab strain)}
2782Rv2788, (MTV002.53), probable transcriptional repressor, len: 228 aa; similar to several eg. TR:P72424 (EMBL:X99128) Staphylococcus epidermidis putative iron dependant repressor sirR (214 aa), fasta scores; opt: 374 z-score: 499.7 E(): 1.1e-20, 33.7% identity i (sirR) {Mycobacterium tuberculosis H37Rv (lab strain)}
2783Rv2789c, (MTV002.54c), len: 410. fadE21, probable Acyl-CoA Dehydrogenas, similar to TR:P97088 (EMBL:Z92974) BUTYRYL-COA DEHYDROGENASE (EC 1.1.1.35) from CLOSTRIDIUM THERMOSACCHAROLYTICUM (379 aa), fasta scores; opt: 597 z-score:816.1 E(): 0, 34.2% identity in 40 (fadE21) {Mycobacterium tuberculosis H37Rv (lab strain)}
2784Rv2790c, (MTV002.55c), len: 401 aa. ltp1, probable lipid-transfer protein, highly similar to many eukaryotic sterol-carrier proteins eg. NLTP_RAT P11915 nonspecific lipid-transfer protein precursor (sterol carrier protein) (547 aa), fasta scores; opt: 1696 z-sco (ltp1) {Mycobacterium tuberculosis H37Rv (lab strain)}
2785Rv2791chypothetical protein Rv2791c {Mycobacterium tuberculosis H37Rv (lab strain)}
2786Rv2792chypothetical protein Rv2792c {Mycobacterium tuberculosis H37Rv (lab strain)}
2787Rv2793c, (MTV002.58c), len: 298. Possible tRNA modification enzyme; similar in N-terminus to many eg. TRUB_ECOLI P09171 trna pseudouridine 55 synthase (314 aa), fasta scores; opt: 574 z-score: 601.4 E(): 2.4e-26, 42.5% identity in 214 aa overlap (truB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2788Rv2794chypothetical protein Rv2794c {Mycobacterium tuberculosis H37Rv (lab strain)}
2789Rv2795chypothetical protein Rv2795c {Mycobacterium tuberculosis H37Rv (lab strain)}
2790Rv2796c, (MTV002.61c-MTCY16B7.47), len 187; Probable lipoprotein similar to MTCY159.13c (220 aa) fasta score:opt: 169 z-score: 206.2 E(): 0.00058; 22.4% identity in196 aa overlap (lppV) {Mycobacterium tuberculosis H37Rv (lab strain)}
2791Rv2797chypothetical protein Rv2797c {Mycobacterium tuberculosis H37Rv (lab strain)}
2792Rv2798chypothetical protein Rv2798c {Mycobacterium tuberculosis H37Rv (lab strain)}
2793Rv2799hypothetical protein Rv2799 {Mycobacterium tuberculosis H37Rv (lab strain)}
2794Rv2800hypothetical protein Rv2800 {Mycobacterium tuberculosis H37Rv (lab strain)}
2795Rv2801chypothetical protein Rv2801c {Mycobacterium tuberculosis H37Rv (lab strain)}
2796Rv2802chypothetical protein Rv2802c {Mycobacterium tuberculosis H37Rv (lab strain)}
2797Rv2803chypothetical protein Rv2803c {Mycobacterium tuberculosis H37Rv (lab strain)}
2798Rv2804chypothetical protein Rv2804c {Mycobacterium tuberculosis H37Rv (lab strain)}
2799Rv2805hypothetical protein Rv2805 {Mycobacterium tuberculosis H37Rv (lab strain)}
2800Rv2806hypothetical protein Rv2806 {Mycobacterium tuberculosis H37Rv (lab strain)}
2801Rv2807hypothetical protein Rv2807 {Mycobacterium tuberculosis H37Rv (lab strain)}
2802Rv2808hypothetical protein Rv2808 {Mycobacterium tuberculosis H37Rv (lab strain)}
2803Rv2809hypothetical protein Rv2809 {Mycobacterium tuberculosis H37Rv (lab strain)}
2804Rv2810chypothetical protein Rv2810c {Mycobacterium tuberculosis H37Rv (lab strain)}
2805Rv2811hypothetical protein Rv2811 {Mycobacterium tuberculosis H37Rv (lab strain)}
2806Rv2812hypothetical protein Rv2812 {Mycobacterium tuberculosis H37Rv (lab strain)}
2807Rv2813hypothetical protein Rv2813 {Mycobacterium tuberculosis H37Rv (lab strain)}
2808Rv2814chypothetical protein Rv2814c {Mycobacterium tuberculosis H37Rv (lab strain)}
2809Rv2815chypothetical protein Rv2815c {Mycobacterium tuberculosis H37Rv (lab strain)}
2810Rv2816chypothetical protein Rv2816c {Mycobacterium tuberculosis H37Rv (lab strain)}
2811Rv2817chypothetical protein Rv2817c {Mycobacterium tuberculosis H37Rv (lab strain)}
2812Rv2818chypothetical protein Rv2818c {Mycobacterium tuberculosis H37Rv (lab strain)}
2813Rv2819chypothetical protein Rv2819c {Mycobacterium tuberculosis H37Rv (lab strain)}
2814Rv2820chypothetical protein Rv2820c {Mycobacterium tuberculosis H37Rv (lab strain)}
2815Rv2821chypothetical protein Rv2821c {Mycobacterium tuberculosis H37Rv (lab strain)}
2816Rv2822chypothetical protein Rv2822c {Mycobacterium tuberculosis H37Rv (lab strain)}
2817Rv2823chypothetical protein Rv2823c {Mycobacterium tuberculosis H37Rv (lab strain)}
2818Rv2824chypothetical protein Rv2824c {Mycobacterium tuberculosis H37Rv (lab strain)}
2819Rv2825chypothetical protein Rv2825c {Mycobacterium tuberculosis H37Rv (lab strain)}
2820Rv2826chypothetical protein Rv2826c {Mycobacterium tuberculosis H37Rv (lab strain)}
2821Rv2827chypothetical protein Rv2827c {Mycobacterium tuberculosis H37Rv (lab strain)}
2822Rv2828chypothetical protein Rv2828c {Mycobacterium tuberculosis H37Rv (lab strain)}
2823Rv2829chypothetical protein Rv2829c {Mycobacterium tuberculosis H37Rv (lab strain)}
2824Rv2830chypothetical protein Rv2830c {Mycobacterium tuberculosis H37Rv (lab strain)}
2825Rv2831, (MTCY16B7.11c), len: 249. echA16, member ofEnoyl-CoA Hydratase/Isomerase Superfamily similar to eg, G755067 enoyl coa hydratase (257 aa), fasta scores, opt: 433,E(): 3.6e-22, (37.6% identity in 226 aa overlap) also MTCY31.33, (36.5 % identity in 170 aa (echA16) {Mycobacterium tuberculosis H37Rv (lab strain)}
2826Rv2832c, (MTCY16B7.10), len: 360 aa. ugpC homologuesimilar to UGPC_ECOLI P10907 sn-glycerol-3-phosphate transport atp-binding protein (356 aa), fasta scores, opt: 953, E(): 0, (44.8% identity in 366 aa overlap) also MTCY9C4.04c,(37.1% identity in 213 aa overlap) (ugpC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2827Rv2833c, (MTCY16B7.09), len: 436 aa, Probable ugpB lipoprotein precursor, similar to UGPB_ECOLI P10904 glycerol-3-phosphate-binding periplasmic protein precursor (438 aa), fasta scores, opt: 254, E(): 1.5e-08, (26.8% identity in414 aa overlap) also MTCY3G12.16c, (ugpB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2828Rv2834c, (MTCY16B7.08), len: 275 aa. ugpE homologuesimilar to UGPE_ECOLI P10906 sn-glycerol-3-phosphate transport system protein (281 aa), fasta scores, opt: 569, E(): 1.1e-31, (32.6% identity in 264 aa overlap) also MTCY3G12.17c (32.4% identity in 278 aa overla (ugpE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2829Rv2835c, (MTCY1B7.07), len: 303. ugpA homologue, similar to UGPA_ECOLI P10905, sn-glycerol-3-phosphate transport system permease protein (295 aa), fasta scores, opt: 477, E(): 5.6e-26, (28.8% identity in 295 aa overlap) also MTCY3G12.18c, (33.8% identity in 278 (ugpA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2830Rv2836c, (MTCY16B7.06), len: 439. dinF homologue, similar to DINF_ECOLI P28303 dna-damage-inducible protein f (459 aa), fasta scores, opt: 491, E(): 1.6e-23, (29.3% identity in 443 aa overlap); contains PS00213 Lipocalin signature (dinF) {Mycobacterium tuberculosis H37Rv (lab strain)}
2831Rv2837chypothetical protein Rv2837c {Mycobacterium tuberculosis H37Rv (lab strain)}
2832Rv2838c, (MTCY16B7.04), len: 183. Probable rbfA, similarity to several RbfA proteins, eg to RBFA_BACSU P32731 ribosome-binding factor a (117 aa), fasta scores, opt: 199, E(): 4.2e-06, (32.4% identity in 108 aa overlap). Longer than other RbfA proteins (rbfA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2833Rv2839c, (MTCY16B7.03), len: 900. Probable infB, initiation factor IF-2 similar at C-terminal half to egIF2_BACSU P17889 initiation factor if-2 (716 aa), fasta scores, opt: 1782, E(): 0, (46.6% identity in 686 aa overlap); contains PS00017 ATP/GTP-binding site m (infB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2834Rv2840chypothetical protein Rv2840c {Mycobacterium tuberculosis H37Rv (lab strain)}
2835Rv2841c, (MTCY24A1.16-MTCY16B7.01), len: 347. nusA similar to eg NUSA_THETH P48514 n-utilization substance protein a homolog (387 aa), fasta scores, opt: 175 z-score: 218.1 E(): 3.7e-05 (28.5% identity in 179 aa overlap) (nusA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2836Rv2842chypothetical protein Rv2842c {Mycobacterium tuberculosis H37Rv (lab strain)}
2837Rv2843hypothetical protein Rv2843 {Mycobacterium tuberculosis H37Rv (lab strain)}
2838Rv2844hypothetical protein Rv2844 {Mycobacterium tuberculosis H37Rv (lab strain)}
2839Rv2845c, (MTCY24A1.12), len: 582 aa, proS, similar to eg SYP_ECOLI P16659 prolyl-trna synthetase (ec 6.1.1.15)( (572 aa), fasta scores, opt: 926 z-score: 1023.6 E(): 0,(39.9% identity in 587 aa overlap), contains PS00179 Aminoacyl-transfer RNA synthetases class- (proS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2840Rv2846c, (MTCY24A1.11), len: 530 aa. efpA, putativeefflux protein, almost identical to EMBL; L39922; G1161051EFFLUX PROTEIN (efpA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2841Rv2847c, (MTCY24A1.10), len: 405 aa. cysG2, possiblemultifunctional enzyme, siroheme synthase, containing uroporphyrin-iii c-methyltransferase, similar over entire length to eg. CYSG_ECOLI P11098 siroheme synthase (457 aa) fastascores; opt: 543 z-score: 606.1 E( (cysG2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2842Rv2848c, (MTCY24A1.09), len 457 aa. cobB, cobyrinicacid a,c-diamide synthase, similar to eg. CBIA_SALTY P29946cobyrinic acid a,c-diamide synthase (459 aa), fasta scores,opt: 831, E(): 0, (36.3% identity in 466 aa overlap). (cobB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2843Rv2849c, (MTCY24A1.08), len: 207 aa. cobA, cob(i)alamin adenosyltransferase, similar to eg. BTUR_SALTY P31570 cob(i)alamin adenosyltransferase (196 aa), fasta scores, opt: 278, E(): 1e-12, (39.3% identity in 196 aa overlap) (cobA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2844Rv2850chypothetical protein Rv2850c {Mycobacterium tuberculosis H37Rv (lab strain)}
2845Rv2851chypothetical protein Rv2851c {Mycobacterium tuberculosis H37Rv (lab strain)}
2846Rv2852chypothetical protein Rv2852c {Mycobacterium tuberculosis H37Rv (lab strain)}
2847Rv2853, (MTCY24A1.04c), len: 615 aa. Member of M. tuberculosis PE family, PGRS subfamily of glycine rich proteins eg Y03A_MYCTU Q10637 hypothetical glycine-rich 49.6 kd pro (603 aa), fasta scores, opt: 1874 z-score: 1309.5 E(): 0, (51.8% identity in 637 aa over (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2848Rv2854hypothetical protein Rv2854 {Mycobacterium tuberculosis H37Rv (lab strain)}
2849Rv2855, (MTCY24A1.02c), len: 459.gorA, Glutathione reductase homolog (gorA). Mycobacterium tuberculosis makes mycothiol instead of glutathione, this GorA homolog may be invovled in reduction of mycothiol; see AF002193_1/sp|O07927. Member of the pyridine nucleot (gorA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2850Rv2856, (MTCY24A1.01c), len: 372 aa. nicT, Possiblenickel transporter, similar to transport proteins and hydrogenase cluster protein, eg HOXN_ALCEU P23516 high-affinitynickel transport protein (351 aa), fasta scores, opt: 903,E(): 0, (41.9% identity in 339 aa o (nicT) {Mycobacterium tuberculosis H37Rv (lab strain)}
2851Rv2857chypothetical protein Rv2857c {Mycobacterium tuberculosis H37Rv (lab strain)}
2852Rv2858c, (MTV003.04c), len: 455 aa. aldC, Probablealdehyde dehydrogenase, aldC; similar to many eg. FEAB_ECOLI P80668 phenylacetaldehyde dehydrogenase (499 aa), fasta scores; opt: 1074 z-score: 1239.2 E(): 0, 42.2% identity in462 aa overlap. Contains PS00687 Ald (aldC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2853Rv2859chypothetical protein Rv2859c {Mycobacterium tuberculosis H37Rv (lab strain)}
2854Rv2860c, (MTV003.06c), unknown, len: 457 aa.glnA4, Probable glutamine synthetase class II, glnA4; similar to many glutamine synthases eg. sp|P10656|GLNA_CLOAB GLUTAMINE SYNTHETASE (EC 6.3.1.2) (443 aa) fasta scores; opt: 609 z-score: 750.0 E(): 0; 30.7% identity (glnA4) {Mycobacterium tuberculosis H37Rv (lab strain)}
2855Rv2861c, (MTV003.07c), len: 285 aa. map, methionineaminopeptidase, similar to many eg. AMPM_ECOLI P07906 methionine aminopeptidase (ec 3.4.11.18) (264 aa), fasta scores;opt: 793 z-score: 1107.5 E(): 0, 51.0% identity in 245 aaoverlap. Note that this gene has an (map) {Mycobacterium tuberculosis H37Rv (lab strain)}
2856Rv2862chypothetical protein Rv2862c {Mycobacterium tuberculosis H37Rv (lab strain)}
2857Rv2863hypothetical protein Rv2863 {Mycobacterium tuberculosis H37Rv (lab strain)}
2858Rv2864chypothetical protein Rv2864c {Mycobacterium tuberculosis H37Rv (lab strain)}
2859Rv2865hypothetical protein Rv2865 {Mycobacterium tuberculosis H37Rv (lab strain)}
2860Rv2866hypothetical protein Rv2866 {Mycobacterium tuberculosis H37Rv (lab strain)}
2861Rv2867chypothetical protein Rv2867c {Mycobacterium tuberculosis H37Rv (lab strain)}
2862Rv2868c, (MTV003.14c), len: 387. gcpE; highly similar to essential gene of unknown function from E. coli and other prokaryotes eg. GCPE_ECOLI P27433 gcpe protein (protein e) (372 aa), fasta scores; opt: 984 z-score: 1272.9 E(): 0, 44.2% identity in 360 aa overla (gcpE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2863Rv2869chypothetical protein Rv2869c {Mycobacterium tuberculosis H37Rv (lab strain)}
2864Rv2870chypothetical protein Rv2870c {Mycobacterium tuberculosis H37Rv (lab strain)}
2865Rv2871hypothetical protein Rv2871 {Mycobacterium tuberculosis H37Rv (lab strain)}
2866Rv2872hypothetical protein Rv2872 {Mycobacterium tuberculosis H37Rv (lab strain)}
2867Rv2873, (MTCY274.04), len: 220. mpt83, identical toMP83_MYCTU CELL SURFACE LIPOPROTEIN MPT83, FASTA scores: Q10790|MP83_MYCTU CELL SURFACE LIPOPROTEIN MPT83 P (239 aa) opt: 1520; E(): 0; 99.6% identity in 239 aa overlap. Also similar to MTCY274.06 which is also (mpt83) {Mycobacterium tuberculosis H37Rv (lab strain)}
2868Rv2874hypothetical protein Rv2874 {Mycobacterium tuberculosis H37Rv (lab strain)}
2869Rv2875, (MTCY274.06), len: 193. mpt70, major secreted immunogenic protein MPT70 precursor, Identical to A48320 major secreted immunogenic protein M (193 aa). FASTA scores: opt: 1200 E(): 0; 100.0% identity in 193 aa overlap. Also similar to MTCY274.04 (Q10790|M (mpt70) {Mycobacterium tuberculosis H37Rv (lab strain)}
2870Rv2876hypothetical protein Rv2876 {Mycobacterium tuberculosis H37Rv (lab strain)}
2871Rv2877c, (MTCY274.08c), len: 287. Similar to MER4_STRLI P30344 mercury resistance probable hg transport system(319 aa), FASTA scores, opt: 427, z-score: 487.1, E(): 1.4e-20, (32.8% identity in 290 aa overlap); contains PS00044 Bacterial regulatory proteins, lysR (merT) {Mycobacterium tuberculosis H37Rv (lab strain)}
2872Rv2878c, (MTCY274.09c), len: 173. dsbE, similar to several disulfide bond interchange proteins e.g. TIPB_PSEFLTHIOL:DISULFIDE INTERCHANGE PROT (178 aa) E(): 4.1e-06 Smith-Waterman score: 184; 26.3% identity in 171 aa overlap. Probably extracytoplasmic, contains (mpt53) {Mycobacterium tuberculosis H37Rv (lab strain)}
2873Rv2879chypothetical protein Rv2879c {Mycobacterium tuberculosis H37Rv (lab strain)}
2874Rv2880chypothetical protein Rv2880c {Mycobacterium tuberculosis H37Rv (lab strain)}
2875Rv2881c, (MTCY274.12c), len: 306, cdsA, similar to CDSA_ECOLI P06466 phosphatidate cytidylyltransferase (249 aa). FASTA scores, opt: 352, z-score: 410.3, E(): 2.6e-16, (40.4% identity in 156 aa overlap); contains PS00017 ATP/GTP-binding site motif A (cdsA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2876Rv2882c, MTCY274.13c, frr, probable ribosome recycling factor, len: 185, similar to RRF_ECOLI P16174, (185 aa)FASTA scores, opt: 473, z-score: 540.8, E(): 1.4e-23, (40.2% identity in 184 aa overlap). Equivalent to M. leprae sp|O33046|O33046 RIBOSOME RECYCLING FA (frr) {Mycobacterium tuberculosis H37Rv (lab strain)}
2877Rv2883c, (MTCY274.14c), len: 261. pyrH, probable uridylate kinase, similar to eg PYRH_ECOLI P29464, (uk) (240 aa), opt: 666, z-score: 757.9, E(): 1.1e-35, (45.7% identity in 232 aa overlap). M.leprae equivalent is sp|O33045|O33045 URIDYLATE KINASE. (279 aa) opt: (pyrH) {Mycobacterium tuberculosis H37Rv (lab strain)}
2878Rv2884hypothetical protein Rv2884 {Mycobacterium tuberculosis H37Rv (lab strain)}
2879Rv2885chypothetical protein Rv2885c {Mycobacterium tuberculosis H37Rv (lab strain)}
2880Rv2886chypothetical protein Rv2886c {Mycobacterium tuberculosis H37Rv (lab strain)}
2881Rv2887hypothetical protein Rv2887 {Mycobacterium tuberculosis H37Rv (lab strain)}
2882Rv2888c, (MTCY274.19c), amiC, len: 473, PUTATIVE AMIDASE (EC 3.5.1.4) also similar to NYLA_PSES8 P13398 6-aminohexanoate-cyclic-dimer hydrolase (492 aa) FASTA scores, opt: 502, z-score: 566.9, E(): 5e-25, (32.9% identity in 474 aa overlap); contains PS00017 ATP/ (amiC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2883Rv2889c, (MTCY274.20c), len: 271. Probable elongation factor tsf, most similar to EFTS_SPIPL P34828 elongationfactor ts (ef-ts) (247 aa) FASTA scores, opt: 509, z-score:539.3, E(): 1.7e-23, (38.3% identity in 253 aa overlap); contains PS01127 Elongation factor T (tsf) {Mycobacterium tuberculosis H37Rv (lab strain)}
2884Rv2890c, (MTCY274.21c), len: 287. rpsB, probable 30s ribosomal protein s2, most similar to RS2_PEDAC P49668, (261 aa) FASTA scores, opt: 934, z-score: 1076.4, E(): 0, (58.1% identity in 248 aa overlap); contains PS00962 Ribosomal protein S2 signature 1 (rpsB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2885Rv2891hypothetical protein Rv2891 {Mycobacterium tuberculosis H37Rv (lab strain)}
2886Rv2892c, (MTCY274.23c), len: 408. Member of PPE family with Z95436|MTY15C10_31 Mycobacterium tuberculosis cosmi (413 aa) opt: 957 z-score: 916.2 E(): 0; 44.7% identity in 423 aa overlap, also similar to MTCY31.06c (53.5% identity in 200 aa overlap) (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2887Rv2893hypothetical protein Rv2893 {Mycobacterium tuberculosis H37Rv (lab strain)}
2888Rv2894c, (MTCY274.25c), len: 298. xerC, integrase/recombinase, most similar to XERC_HAEIN P44818 integrase/recombinase xerc, (295 aa), opt: 627, z-score: 726.6, E(): 6.3e-34, (39.9% identity in 296 aa overlap). M. leprae equivalent is sp|O33037|O33037 XERC PROTE (xerC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2889Rv2895c, (MTCY274.26c), len: 283. Some similarity to proteins from Vibrio sp. involved in catechol siderophoreutilization e.g. U11759|VCVIUAB1 VCVIUAB NID: g517206 - Vibrio chol (271 aa) FASTA: opt: 395 E(): 4.6e-18; 31.0% identity in 274 aa overlap (viuB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2890Rv2896chypothetical protein Rv2896c {Mycobacterium tuberculosis H37Rv (lab strain)}
2891Rv2897chypothetical protein Rv2897c {Mycobacterium tuberculosis H37Rv (lab strain)}
2892Rv2898chypothetical protein Rv2898c {Mycobacterium tuberculosis H37Rv (lab strain)}
2893Rv2899c, (MTCY274.30c), len: 276. fdhD, similar to bacterial fdhd proteins, eg FDHD_HAEIN P44449, fdhd protein, Haemophilus influenzae, (270 aa) FASTA scores, opt: 336, z-score: 381.1, E(): 1.1e-14, (32.1% identity in 252 aa overlap) (fdhD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2894Rv2900c, (MTCY274.31c), len: 779. fdhF. Similar to FdhF and other prokaryotic molybdopterin-containing oxidoreductases e.g. REU60056 NID: g1620507 - Ralstonia (757 aa) FASTA scores opt: 2050 E(): 0; Smith-Waterman score: 2050; 45.0% identity in 746 aa overlap. A (fdhF) {Mycobacterium tuberculosis H37Rv (lab strain)}
2895Rv2901chypothetical protein Rv2901c {Mycobacterium tuberculosis H37Rv (lab strain)}
2896Rv2902c, (MTCY274.33c), len: 264. rnhB, ribonuclease HII, similar to eg RNH2_ECOLI P10442 ribonuclease hii, (213 aa) FASTA scores, opt: 519, z-score: 609.4, E(): 2.1e-27, (48.6% identity in 183 aa overlap) (rnhB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2897Rv2903c, (MTCY274.34c), len: 294. lepB, signal peptidase I, similar to many eg LEP_BACLI P42668 signal peptidase i, (186 aa), FASTA scores, opt: 218, z-score: 256.4, E(): 9.9e-08, (34.5% identity in 194 aa overlap); contains PS00501 Signal peptidases I serine ac (lepB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2898Rv2904c, (MTCY274.35c), len: 113. rplS, 50S ribosomal protein L19, similar to eg RL19_BACST P30529, (116 aa) FASTA scores, opt: 518, z-score: 642.0, E(): 3.3e-29, (71.7%identity in 106 aa overlap) (rplS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2899Rv2905, (MTCY274.36), len: 314. Unknown lipoproteinhas signal peptide and appropriately positioned prokaryoticlipoprotein lipid attachment site. Slight similarity to beta-lactamase. FASTA score: P14559|BLAC_STRAL BETA-LACTAMASEPRECURSOR (EC 3.5 (314 aa) opt: 11 (lppW) {Mycobacterium tuberculosis H37Rv (lab strain)}
2900Rv2906c, (MTCY274.37c), len: 230. trmD, trna m1G methyltransferase, similar to eg TRMD_ECOLI P07020 trna (guanine-n1)-methyltransferase (255 aa) FASTA scores, opt: 573, z-score: 712.6, E(): 3.8e-33, (42.1% identity in 228 aa overlap) (trmD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2901Rv2907c, (MTCY274.38c), unknown, len: 176, similar to RIMM_ECOLI 16S RRNA PROCESSING PROTEIN RIMM. (185 aa). FASTA scores, opt: 249, z-score: 305.2, E(): 1.9e-10, (29.2%identity in 185 aa overlap). Equivalent to M. leprae sp|O33016|O33016 HYPOTHETICAL 19.3 KD PR (rimM) {Mycobacterium tuberculosis H37Rv (lab strain)}
2902Rv2908chypothetical protein Rv2908c {Mycobacterium tuberculosis H37Rv (lab strain)}
2903Rv2909c, (MTCY274.41c), len: 162. rpsP, 30S ribosomal protein S16, similar to eg RS16_BACSU P21474 30s ribosomal protein s16 (bs17). (89 aa) FASTA scores, opt: 258, z-score: 277.9, E(): 6.2e-09, (42.9% identity in 91 aa overlap) (rpsP) {Mycobacterium tuberculosis H37Rv (lab strain)}
2904Rv2910chypothetical protein Rv2910c {Mycobacterium tuberculosis H37Rv (lab strain)}
2905Rv2911, (MTCY274.43), dacB, len: 291. Similar to penicillin binding proteins, eg DACB_BACSU PENICILLIN-BINDINGPROTEIN 5* PR (382 aa) opt: 384 E(): 3.6e-17; 30.7% identity in 244 aa overlap; PBP7_ECOLI P33364 penicillin-bindingprotein 7 precursor (313 aa) FASTA (dacB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2906Rv2912chypothetical protein Rv2912c {Mycobacterium tuberculosis H37Rv (lab strain)}
2907Rv2913chypothetical protein Rv2913c {Mycobacterium tuberculosis H37Rv (lab strain)}
2908Rv2914c, (MTCY338.02c), len: 585, Probable serine/threonine-protein kinase similar to many in M. tuberculosisand other bacteria eg PKN1_MYXXA P33973 serine/threonine-protein kinase pkn1, (693 aa) FASTA scores, opt: 286, z-score: 296.9, E(): 5.4e-10, (29.9% ident (pknI) {Mycobacterium tuberculosis H37Rv (lab strain)}
2909Rv2915chypothetical protein Rv2915c {Mycobacterium tuberculosis H37Rv (lab strain)}
2910Rv2916c, (MTCY338.04c), ffh, signal recognition particle protein, len: 525, similar to eg SR54_BACSU P37105 signal recognition particle protein (fifty-four homologue, (446 aa) FASTA scores, opt: 1451, z-score: 1409.6 E(): 0,Smith-Waterman score: 1451; (51.5% ide (ffh) {Mycobacterium tuberculosis H37Rv (lab strain)}
2911Rv2917hypothetical protein Rv2917 {Mycobacterium tuberculosis H37Rv (lab strain)}
2912Rv2918c, (MTCY338.07c), len: 808. glnD, Probable uridylyltransferase, similar to eg GLND_ECOLI P27249 [protein-pii] (890 aa) FASTA scores, opt: 306, z-score: 339.0, E():2.5e-12, (27.7% identity in 857 aa overlap). (glnD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2913Rv2919c, (MTCY338.08c), len: 112,glnB, Probable nitrogen regulatory protein GlnB, Q10960, highly similar to GLNB_ECOLI P05826, (112 aa) FASTA scores, opt: 487, z-score: 605.2, E(): 3.6e-27, (61.6% identity in 112 aa overlap); contains PS00496 P-II protein urydyl (glnB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2914Rv2920c, (MTCY338.09c), len: 477. Probable ammoniumtransporter, amt, belongs to AMT1/MEP/NRGA FAMILY OF AMMONIUM TRANSPORTERS; similar to NRGA_BACSU Q07429 membrane protein nrga, (404 aa) FASTA scores, opt: 721, z-score: 856.4,E(): 0, (44.4% identity in 430 aa o (amt) {Mycobacterium tuberculosis H37Rv (lab strain)}
2915Rv2921c, (MTCY338.10c), len: 422. ftsY, Probable cell division protein FtsY, Q10969, similar to eg FTSY_ECOLIP10121, cell division protein ftsy (497 aa), FASTA scores,opt: 800, z-score: 819.9, E(): 4e-39, (40.9% identity in 328 aa overlap): contains PS00017 ATP/ (ftsY) {Mycobacterium tuberculosis H37Rv (lab strain)}
2916Rv2922c, (MTCY338.11c), len: 1289. smc. Homolog of chromosome segregation protein, SMC, Q10970 BELONGS TO THE SMC1/CUT3/CUT14 FAMILY. Similar to sp|O31735|O31735 CHROMOSOME SEGREGATION SMC PROTEIN HO (1186 aa) opt: 1009 z-score: 915.2 E(): 0; 30.8% identity in 1 (smc) {Mycobacterium tuberculosis H37Rv (lab strain)}
2917Rv2923chypothetical protein Rv2923c {Mycobacterium tuberculosis H37Rv (lab strain)}
2918Rv2924c, (MTCY338.13c), len: 289.fpg, Probable formamidopyrimidine-dna glycosylase, Q10959;, similar to eg FPG_ECOLI P05523 (269 aa) FASTA scores, opt: 424, z-score: 509.3, E(): 8e-22, (34.1% identity in 290 aa overlap) (fpg) {Mycobacterium tuberculosis H37Rv (lab strain)}
2919Rv2925c, (MTCY338.14c), len: 240. RNase III, Q10962; RNC_ECOLI P05797 ribonuclease III, (226 aa) opt: 459, z-score: 563.7, E(): 7.5e-25, (41.8% identity in 213 aa overlap); contains PS00517 Ribonuclease III family signature (rnc) {Mycobacterium tuberculosis H37Rv (lab strain)}
2920Rv2926chypothetical protein Rv2926c {Mycobacterium tuberculosis H37Rv (lab strain)}
2921Rv2927chypothetical protein Rv2927c {Mycobacterium tuberculosis H37Rv (lab strain)}
2922Rv2928, (MTCY338.17), len: 261. Probable thioesterase, most similar to PABT_STRGR P33586 probable cadicidin biosynthesis thioesterase (361 aa) FASTA scores, opt: 493, z-score: 589.3, E(): 2.8e-26, (35.8% identity in 240 aa overlap) (tesA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2923Rv2929hypothetical protein Rv2929 {Mycobacterium tuberculosis H37Rv (lab strain)}
2924Rv2930, (MTCY338.19), len: 626.fadD26, Probable Acyl-CoA Synthetase similar to several e.g. YMA2_MYCBO Q02278 hypothetical 32.3 kd protein in mas 5 region (298 aa) FASTA scores, opt: 1104, z-score: 1251.2, E(): 0, (58.0% identity in 288 aa overlap) (fadD26) {Mycobacterium tuberculosis H37Rv (lab strain)}
2925Rv2931, (MTCY338.20), len: 1876. Polyketide synthase involved in Phenolpthiocerol Synthesis, similar many e.g.to MSAS_PENPA P22367 6-methylsalicylic acid synthase (ec 2(1774 aa) FASTA scores, opt: 2391, z-score: 2478.9, E(): 0,(34.2% identity in 1815 aa overlap (ppsA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2926Rv2932, (MTV011.01-MTCY338.21), len 1538. Polyketide synthase involved in Phenolpthiocerol Synthesis. Highly similar to many eg. M. leprae TR:Q49932 (EMBL:U00023) PUTATIVE POLYKETIDE SYNTHASE PKSC (L518_F1_2) (1446 aa), fasta scores; opt: 5614 z-score: 4262.0 E (ppsB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2927Rv2933, (MTCY19H9.01-MTV011.02), len: 2188. Polyketide synthase involved in Phenolpthiocerol Synthesis. Highlysimilar to G467200 PKSD (2201 aa), fasta scores, opt: 6973,E(): 0, (80.4% identity in 1842 aa overlap); contains PS00012 Phosphopantetheine attachment (ppsC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2928Rv2934, (MTCY19H9.02), len: 1827 aa. Polyketide synthase involved in Phenolpthiocerol Synthesis. Highly similar to G467207 PKSE (1815 aa), fasta scores, opt: 9658, E(): 0, (79.8% identity in 1831 aa overlap); contains PS00606 Beta-ketoacyl synthases active site (ppsD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2929Rv2935, (MTCY19H9.03), len: 1488 aa, Phenolpthiocerol Synthesis. Highly similar to G467201 PKSF, (1489 aa), fasta scores, opt: 8156, E(): 0, (82.0% identity in 1493 aa overlap); contains PS00606 Beta-ketoacyl synthases active site (ppsE) {Mycobacterium tuberculosis H37Rv (lab strain)}
2930Rv2936, (MTCY19H9.04), len: 331 aa. drrA, highly similar to G467205 DRRA daunorubicin resistance atp-binding protein (331 aa), fasta scores, opt: 1842, E(): 0, (85.2% identity in 331 aa overlap); PS00017 ATP/GTP-binding site motif A, PS00211 ABC transporters fa (drrA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2931Rv2937, (MTCY19H9.05), len: 289 aa. drrB, highly similar to G467202 DRRB daunorubicin resistance transmembraneprotein, (288 aa), fasta scores, opt: 1252, E(): 0, (64.0%identity in 289 aa overlap) (drrB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2932Rv2938, (MTCY19H9.06), len: 276 aa. drrC, highly similar to G467208 DRRC (244 aa), fasta scores, opt: 1194, E(): 0, (76.9% identity in 242 aa overlap) (drrC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2933Rv2939, (MTCY19H9.07), len: 422 aa, papA5, Polyketide synthase associated protein, Pap5. Highly similar to G467206 UL518A (423 aa), fasta scores, opt: 2398, E(): 0, (84.0% identity in 426 aa overlap), also YMA3_MYCBO Q02279 hypothetical 38.1 kd protein in mas 3 (papA5) {Mycobacterium tuberculosis H37Rv (lab strain)}
2934Rv2940c, (MTCY24G1.09-MTCY19H9.08c), len: 2111, Mycocerosic acid synthase, almost identical to M. bovis MCAS_MYCBO Q02251 Mycocerosic acid synthase (2110 aa), fasta scores, opt: 12812, E(): 0, (95.7% identity in 2046 aa overlap), highly similar to G466793 MASA, (mas) {Mycobacterium tuberculosis H37Rv (lab strain)}
2935Rv2941, (MTCY24G1.08c), len: 580 aa,fadD28, Probable Acyl-CoA Synthetase, similar to many e.g. Y06J_MYCTU Q10976 hypothetical 67.9 kd protein cy338.19 (626 aa), fasta scores, opt: 2337, E(): 0, (57.7% identity in 619 aa overlap), also MTCY19G5.07, (64% identity (fadD28) {Mycobacterium tuberculosis H37Rv (lab strain)}
2936Rv2942, (MTCY24G1.07c), len: 920 aa. mmpL1, member of Conserved Mycobacterial Membrane Protein. Similarity to gp|AL021932|MTV037_14 Mycobacterium tuberculosis seque (967aa) opt: 481 z-score: 521.3 E(): 1.6e-21; 25.9% identity in 922 aa overlap; and to YV34_MYCL (mmpL7) {Mycobacterium tuberculosis H37Rv (lab strain)}
2937Rv2943hypothetical protein Rv2943 {Mycobacterium tuberculosis H37Rv (lab strain)}
2938Rv2944hypothetical protein Rv2944 {Mycobacterium tuberculosis H37Rv (lab strain)}
2939Rv2945c, (MTCY24G1.04), len: 233 aa, Probable lipoprotein, similar to Y08C_MYCTU Q11049 hypothetical 26.4 kd protein cy50.12. (257 aa), fasta scores, opt: 309, E(): 3.9e-13, (30.8% identity in 240 aa overlap), also MTCY21B4.28c,(32% identity in 231 aa overlap); (lppX) {Mycobacterium tuberculosis H37Rv (lab strain)}
2940Rv2946c, (MTCY24G1.03), len: 1616 aa. Probable polyketide Synthase, almost identical to G560507 PKS002C (fragment) (950 aa) opt: 5685, E(): 0, (95.3% identity in 927 aa overlap); PS00012 Phosphopantetheine attachment site (pks1) {Mycobacterium tuberculosis H37Rv (lab strain)}
2941Rv2947c, (MTCY24G1.02), len: 496 aa, Probable polyketide synthase, almost identical to G560508 PKS002B (495 aa), fasta scores, opt: 3270, E(): 0, (99.6% identity in 496 aa overlap); contains PS00606 Beta-ketoacyl synthases active site; similar to MTCY338.20 (49. (pks15) {Mycobacterium tuberculosis H37Rv (lab strain)}
2942Rv2948c, (MTCY24G1.01), len: 705 aa. fadD22, Probable Acyl-CoA Synthetase. Almost identical to G560509 PKS002A(705 aa), fasta scores, opt: 4647, E(): 0, (99.7% identityin 705 aa overlap) (fadD22) {Mycobacterium tuberculosis H37Rv (lab strain)}
2943Rv2949chypothetical protein Rv2949c {Mycobacterium tuberculosis H37Rv (lab strain)}
2944Rv2950c, (MTCY349.40), len: 619 aa.fadD29, Probable Acyl-CoA Synthetas, similar to various mycobacterial enzymes believed to be involved in polyketide or fatty acid synthesis such as G466799 MASC. FASTA best: Y06J_MYCTU Q10976 hypothetical 67.9 kd protein cy338. (fadD29) {Mycobacterium tuberculosis H37Rv (lab strain)}
2945Rv2951chypothetical protein Rv2951c {Mycobacterium tuberculosis H37Rv (lab strain)}
2946Rv2952hypothetical protein Rv2952 {Mycobacterium tuberculosis H37Rv (lab strain)}
2947Rv2953hypothetical protein Rv2953 {Mycobacterium tuberculosis H37Rv (lab strain)}
2948Rv2954chypothetical protein Rv2954c {Mycobacterium tuberculosis H37Rv (lab strain)}
2949Rv2955chypothetical protein Rv2955c {Mycobacterium tuberculosis H37Rv (lab strain)}
2950Rv2956hypothetical protein Rv2956 {Mycobacterium tuberculosis H37Rv (lab strain)}
2951Rv2957hypothetical protein Rv2957 {Mycobacterium tuberculosis H37Rv (lab strain)}
2952Rv2958chypothetical protein Rv2958c {Mycobacterium tuberculosis H37Rv (lab strain)}
2953Rv2959chypothetical protein Rv2959c {Mycobacterium tuberculosis H37Rv (lab strain)}
2954Rv2960chypothetical protein Rv2960c {Mycobacterium tuberculosis H37Rv (lab strain)}
2955Rv2961hypothetical protein Rv2961 {Mycobacterium tuberculosis H37Rv (lab strain)}
2956Rv2962chypothetical protein Rv2962c {Mycobacterium tuberculosis H37Rv (lab strain)}
2957Rv2963hypothetical protein Rv2963 {Mycobacterium tuberculosis H37Rv (lab strain)}
2958Rv2964, (MTCY349.23c), len: 310 aa. Identical to formyltetrahydrofolate deformylase G560524 purU (310 aa) (purU) {Mycobacterium tuberculosis H37Rv (lab strain)}
2959Rv2965c, (MTCY349.22), len: 161 aa. kdtB, identicalto G560525 U0002E, similar to KDTB_ECOLI P23875 lipopolysaccharide core biosynthesis protein (159 aa), fasta scores, opt: 459, E(): 8.5e-26, (45.2% identity in 155 aa overlap) (kdtB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2960Rv2966chypothetical protein Rv2966c {Mycobacterium tuberculosis H37Rv (lab strain)}
2961Rv2967c, (MTCY349.20), len: 1127 aa. pca, pyruvate carboxylase, nearly identical to G560527 cosmid tbc2 (1124 aa); contains PS00867 Carbamoyl-phosphate synthase subdomain signature 2, PS00165 Serine/threonine dehydratases pyridoxal-phosphate attachment site, PS0 (pca) {Mycobacterium tuberculosis H37Rv (lab strain)}
2962Rv2968chypothetical protein Rv2968c {Mycobacterium tuberculosis H37Rv (lab strain)}
2963Rv2969chypothetical protein Rv2969c {Mycobacterium tuberculosis H37Rv (lab strain)}
2964Rv2970c, (MTCY349.17), len: 376 aa. Probable lipase/esterase, similar to several eg G695278 lipase-like enzyme(364 aa), fasta scores, opt: 665, E(): 4e-36, (39.4% identity in 327 aa overlap) (lipN) {Mycobacterium tuberculosis H37Rv (lab strain)}
2965Rv2971hypothetical protein Rv2971 {Mycobacterium tuberculosis H37Rv (lab strain)}
2966Rv2972chypothetical protein Rv2972c {Mycobacterium tuberculosis H37Rv (lab strain)}
2967Rv2973c, (MTCY349.14), len: 737 aa. Probable recG, similar to eg T. pallidum sp|P96130|P96130 RECG. (686 aa) fasta scores, opt: 644 z-score: 769.9 E(): 0; 34.9% identity in 527 aa overlap; and RECG_ECOLI P24230 atp-dependent dna helicase recg (693 aa), fasta sco (recG) {Mycobacterium tuberculosis H37Rv (lab strain)}
2968Rv2974chypothetical protein Rv2974c {Mycobacterium tuberculosis H37Rv (lab strain)}
2969Rv2975chypothetical protein Rv2975c {Mycobacterium tuberculosis H37Rv (lab strain)}
2970Rv2976c, (MTCY349.11), len: 227 aa. ung, probable uracil-DNA glycosylase; similar to eg UNG_BACSU P39615 uracil-dna glycosylase (225 aa), fasta scores, opt: 625, E(): 1e-35, (45.5% identity in 222 aa overlap) (ung) {Mycobacterium tuberculosis H37Rv (lab strain)}
2971Rv2977c, (MTCY349.10), len: 333 aa. Possible thiL, similar to several thiamin-monophosphate kinases THIL_ECOLIP77785 thiamin-monophosphate kinase (ec 2.7. (325 aa) FASTAscores: opt: 418 E(): 7.8e-19; (36.9% identity in 282 aaoverlap). Note the start, as given, i (thiL) {Mycobacterium tuberculosis H37Rv (lab strain)}
2972Rv2978chypothetical protein Rv2978c {Mycobacterium tuberculosis H37Rv (lab strain)}
2973Rv2979chypothetical protein Rv2979c {Mycobacterium tuberculosis H37Rv (lab strain)}
2974Rv2980hypothetical protein Rv2980 {Mycobacterium tuberculosis H37Rv (lab strain)}
2975Rv2981c, (MTCY349.06), len: 373 aa. Probable ddlA, similar to eg DDLA_ECOLI P23844 d-alanine-d-alanine ligase a (364 aa), fasta scores, opt: 938, E(): 0, (44.5% identityin 364 aa overlap); contains PS00843 D-alanine--D-alanine ligase signature 1 (ddlA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2976Rv2982c, (MTCY349.05), len: 334 aa. gpdA2, similar to eg GPDA_BACSU P46919 glycerol-3-phosphate dehydrogenase (345 aa), fasta scores, opt: 872, E(): 0, (44.9% identity in 325 aa overlap). Equivalent to M. leprae sp|O33129|O33129GLYCEROL-3-PHOSPHATE DEHYDROGENASE (gpdA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
2977Rv2983hypothetical protein Rv2983 {Mycobacterium tuberculosis H37Rv (lab strain)}
2978Rv2984, (MTCY349.03c), len: 742 aa. ppk, similar toeg G755167 polyphosphate kinase (685 aa), fasta scores, opt: 1263, E(): 0, (41.7% identity in 702 aa overlap). Equivalent to M. leprae sp|O33127|O33127 POLYPHOSPHATE KINASE (739 aa) opt: 4264 z-score: 4869.2 E( (ppk) {Mycobacterium tuberculosis H37Rv (lab strain)}
2979Rv2985, (MTCY349.02c), len: 317 aa. Equivalent to M. leprae sp|O33126|O33126 HYPOTHETICAL 34.5 KD PROTEIN.(312aa) opt: 1514 z-score: 1817.8 E(): 0; 71.8% identity in 316 aa overlap; also some similarity with G886310, M.leprae L222-ORF6 (251 aa), fasta scores, o (mutT1) {Mycobacterium tuberculosis H37Rv (lab strain)}
2980Rv2986c, (MTCY349.01), len: 214 aa. Probable hupB, resembles fusion between HU and histone. Equivalent to M. leprae sp|O33125|O33125 HISTONE-LIKE DNA BINDING PROTEIN. (200 aa) opt: 914 z-score: 751.6 E(): 0; 80.1% identity in 216 aa overlap; also similar at N-te (hupB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2981Rv2987c, (MTV012.01c), len: 198. leuD, 3-isopropylmalate dehydratase small subunit (ec 4.2.1.33), similar to many e.g. S. typhimurium leuD P04787, best with M. leprae. FASTA score: gp|Z99263|MLCB637_33 Mycobacterium leprae cosmid B637. (198 aa) opt: 1155 z-score (leuD) {Mycobacterium tuberculosis H37Rv (lab strain)}
2982Rv2988c, (MTV012.02c), len: 473. leuC, 3-isopropylmalate dehydratase large subunit, similar to many e.g. A.teichomyceticus leuC (X84647) best with M. leprae (Z99263|MLCB637_32). FASTA score: gp|Z99263|MLCB637_32 Mycobacterium leprae cosmid B637. (476 aa) opt: 28 (leuC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2983Rv2989hypothetical protein Rv2989 {Mycobacterium tuberculosis H37Rv (lab strain)}
2984Rv2990chypothetical protein Rv2990c {Mycobacterium tuberculosis H37Rv (lab strain)}
2985Rv2991hypothetical protein Rv2991 {Mycobacterium tuberculosis H37Rv (lab strain)}
2986Rv2992c, (MTV012.06c), len: 490. gltS, Glutamyl-tRNA synthase, gltX, similar to many eg. Bacillus subtilis glutamyl-tRNA synthase BACGLTXA_1, best with M. leprae. FASTA score: gp|Z99263|MLCB637_29 Mycobacterium leprae (502 aa) opt: 2660 z-score: 3226.7 E(): 0; ( (gltS) {Mycobacterium tuberculosis H37Rv (lab strain)}
2987Rv2993chypothetical protein Rv2993c {Mycobacterium tuberculosis H37Rv (lab strain)}
2988Rv2994hypothetical protein Rv2994 {Mycobacterium tuberculosis H37Rv (lab strain)}
2989Rv2995c, (MTV012.09), len: 336. 3-isopropylmalate dehydrogenase, leuB, identical to M. tuberculosis enzyme. FASTA score: sptr|P95313|P95313 3-ISOPROPYLMALATE DEHYDROGENASE (336 aa) opt: 2175 z-score: 2511.9 E(): 0; (100.0% identity in 336 aa overlap). TBparse sc (leuB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2990Rv2996c, (MTV012.10), len: 528. D-3-phosphoglycerate dehydrogenase, serA, similar to many e.g. JU67544_7 Methanococcus jannaschii (524 aa), best with M. leprae serA 9MLCB637_25). Contains PS00017 ATP/GTP-binding site motif A (P-loop), PS00065 D-isomer specific 2 (serA) {Mycobacterium tuberculosis H37Rv (lab strain)}
2991Rv2997hypothetical protein Rv2997 {Mycobacterium tuberculosis H37Rv (lab strain)}
2992Rv2998hypothetical protein Rv2998 {Mycobacterium tuberculosis H37Rv (lab strain)}
2993Rv2999, (MTV012.13), len: 321. Unknown lipoprotein highly similar to Mycobacterium tuberculosis hypothetical protein MTCY19H5.18c. FASTA score: gp|Z97182|MTCY19H5_18 (316 aa) opt: 1153 z-score: 1164.2 E(): 0; (53.2% identity in 312 aa overlap). Contains probabl (lppY) {Mycobacterium tuberculosis H37Rv (lab strain)}
2994Rv3000hypothetical protein Rv3000 {Mycobacterium tuberculosis H37Rv (lab strain)}
2995Rv3001c, (MTV012.15c), len: 333. Ketol-acid reductoisomerase, ilvC, similar to many eg. ILVC_MYCAV Q59500 (333aa). FASTA score: sp|Q59500|ILVC_MYCAV KETOL-ACID REDUCTOISOMERASE (333 aa) opt: 1977 z-score: 2361.0 E(): 0; (87.7% identity in 333 aa overlap). TBpars (ilvC) {Mycobacterium tuberculosis H37Rv (lab strain)}
2996Rv3002c, (MTV012.16c), len: 168. Acetolactate synthase small subunit, ilvN, similar to many eg Mycobacterium leprae MLCB637.21. FASTA score: gp|Z99263|MLCB637_21 Mycobacterium leprae cosmid B637. (169 aa) opt: 843 z-score: 1038.0 E(): 0; (83.5% identity in 164 a (ilvN) {Mycobacterium tuberculosis H37Rv (lab strain)}
2997Rv3003c, (MTV012.17c), len: 618. Acetolactate synthase large subunit, ilvB, similar to many eg. MLCB637_20 from Mycobacterium leprae. Contains PS00187 Thiamine pyrophosphate enzymes signature. Also shows similarity to MTCY1A11.23c. FASTA score: gp|Z99263|MLCB637 (ilvB) {Mycobacterium tuberculosis H37Rv (lab strain)}
2998Rv3004hypothetical protein Rv3004 {Mycobacterium tuberculosis H37Rv (lab strain)}
2999Rv3005chypothetical protein Rv3005c {Mycobacterium tuberculosis H37Rv (lab strain)}
3000Rv3006, (MTV012.20), len: 373. Unknown but equivalent to M. leprae lipoprotein MLCB637.17c. Contains signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site, followed by a proline-rich domain. FASTA score: gp| (lppZ) {Mycobacterium tuberculosis H37Rv (lab strain)}
3001Rv3007chypothetical protein Rv3007c {Mycobacterium tuberculosis H37Rv (lab strain)}
3002Rv3008hypothetical protein Rv3008 {Mycobacterium tuberculosis H37Rv (lab strain)}
3003Rv3009c, (MTV012.23c), len: 509. Probable gatB, Glu-tRNA-Gln amidotransferase subunit B. Similar to several e.g. G2589196 (476 aa) See Proc Natl Acad Sci U S A 1997 Oct28;94(22):11819-11826. Equivalent to Mycobacterium leprae protein MLCB637_15, len: 509 aa; sim (gatB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3004Rv3010c, (MTV012.24c), len: 343. Phosphofructokinase, pfkA, similar to many, best with Mycobacterium leprae MLCB637.14. Contains PS00433 Phosphofructokinase signature. FASTA score: gp|Z99263|MLCB637_14 (348 aa) opt: 2099 z-score: 2588.0 E(): 0; (90.4% identity i (pfkA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3005Rv3011c, (MTV012.25c), len: 494. Probable gatA, Glu-tRNA-Gln amidotransferase subunit A similar to several e.g. G2589195 (486 aa). See Proc Natl Acad Sci U S A 1997 Oct28;94(22):11819-11826. Similar to many prokaryotic and eukaryotic amidases, best with Mycobact (gatA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3006Rv3012c, (MTV012.26c), len: 99. Probably corresponds to gatC, Glu-tRNA-Gln amidotransferase subunit C similar to several e.g. G2589194 (96 aa). See Proc Natl Acad Sci U S A 1997 Oct 28;94(22):11819-11826. Equivalent to hypothetical protein MLCB637.12 from Mycoba (gatC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3007Rv3013hypothetical protein Rv3013 {Mycobacterium tuberculosis H37Rv (lab strain)}
3008Rv3014c, (MTV012.28c), len: 691. Probable ligA, DNAligase, similar to many prokaryotic and eukaryotic ligases,best with M. leprae MLCB637.10. FASTA score: Z99263|MLCB637_10 Mycobacterium leprae cosmid B637. (694 aa) opt: 3844 z-score: 4389.1 E(): 0; (84.7% ident (ligA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3009Rv3015chypothetical protein Rv3015c {Mycobacterium tuberculosis H37Rv (lab strain)}
3010Rv3016, (MTV012.30), len: 209. Unknown, probable lipoprotein. Contains signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. TBparse score is 0.921 (lpqA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3011Rv3017chypothetical protein Rv3017c {Mycobacterium tuberculosis H37Rv (lab strain)}
3012Rv3018c, (MTV012.32c), len: 434. Unknown, member ofPPE family but lacks Gly, Ala rich repeats at C-terminal domain, closest to MTCY261.19. Also very similar to followingorf MTV012.35c. Nearly identical in parts to M. tuberculosis protein erroneously described as (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3013Rv3019chypothetical protein Rv3019c {Mycobacterium tuberculosis H37Rv (lab strain)}
3014Rv3020c, (MTV012.34c), len: 97. Unknown, but memberof M. tuberculosis PE family. Has potential helix-turn-helix motif at positions 14-35. FASTA score: Z95387|MTCY1A10_19(461 aa) opt: 107 z-score: 150.2 E(): 0.7; (30.2% identity in 96 aa overlap). TBparse score i (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3015Rv3021c, (MTV012.35c), len: 358. Member of M. tuberculosis PPE family. Should be continuation of upstream orf MTV012.36c but is frameshifted due to missing base at 36448in v012. Sequence has been checked but no error apparent. Very similar to neighbouring orf MT (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3016Rv3022c, (MTV012.36c), len: 81. Member of M. tuberculosis PPE family with frameshift due to missing bp in in codon 82. The orf continues in downstream MTV012.35c. The sequence has been checked and no errors were detected. Identical to neigbouring orf MTV012.32c. (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3017Rv3023chypothetical protein Rv3023c {Mycobacterium tuberculosis H37Rv (lab strain)}
3018Rv3024chypothetical protein Rv3024c {Mycobacterium tuberculosis H37Rv (lab strain)}
3019Rv3025chypothetical protein Rv3025c {Mycobacterium tuberculosis H37Rv (lab strain)}
3020Rv3026chypothetical protein Rv3026c {Mycobacterium tuberculosis H37Rv (lab strain)}
3021Rv3027chypothetical protein Rv3027c {Mycobacterium tuberculosis H37Rv (lab strain)}
3022Rv3028c, (MTV012.43c), len: 318. fixB. Probable electron transfer flavoprotein alpha subunit for various dehydrogenases. Equivalent to Mycobacterium leprae FixB; MLCB637.04, FASTA score: Z99263|MLCB637_4 Mycobacterium leprae cosmid B637. (318 aa) opt: 1788 z-sco (fixB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3023Rv3029c, (MTV012.44c), len: 266 aa. fixA, Probable electron transfer flavoprotein beta-subunit. Equivalent of Mycobacterium leprae FixA protein; MLCB637.03, FASTA score:Z99263|MLCB637_3 (266 aa) opt: 1603 z-score: 1883.0 E(): 0;(95.1% identity in 266 aa overlap) (fixA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3024Rv3030hypothetical protein Rv3030 {Mycobacterium tuberculosis H37Rv (lab strain)}
3025Rv3031hypothetical protein Rv3031 {Mycobacterium tuberculosis H37Rv (lab strain)}
3026Rv3032hypothetical protein Rv3032 {Mycobacterium tuberculosis H37Rv (lab strain)}
3027Rv3033hypothetical protein Rv3033 {Mycobacterium tuberculosis H37Rv (lab strain)}
3028Rv3034chypothetical protein Rv3034c {Mycobacterium tuberculosis H37Rv (lab strain)}
3029Rv3035hypothetical protein Rv3035 {Mycobacterium tuberculosis H37Rv (lab strain)}
3030Rv3036chypothetical protein Rv3036c {Mycobacterium tuberculosis H37Rv (lab strain)}
3031Rv3037chypothetical protein Rv3037c {Mycobacterium tuberculosis H37Rv (lab strain)}
3032Rv3038chypothetical protein Rv3038c {Mycobacterium tuberculosis H37Rv (lab strain)}
3033Rv3039c, (MTV012.54c), len: 254. echA17, Enoyl-CoA Hydratase/Isomerase Superfamily member, echA17. Probable enoyl-CoA hydratase, similar to many closest to Mycobacteriumleprae B1306.05c protein. FASTA score: Y13803|MLB1306_5 Mycobacterium leprae cosmid B1306 (25 (echA17) {Mycobacterium tuberculosis H37Rv (lab strain)}
3034Rv3040chypothetical protein Rv3040c {Mycobacterium tuberculosis H37Rv (lab strain)}
3035Rv3041chypothetical protein Rv3041c {Mycobacterium tuberculosis H37Rv (lab strain)}
3036Rv3042c, (MTV012.57c), len: 409. The C-terminal domain (150-409) is highly similar to several SerB proteins e.g. P06862|SERB_ECOLI. N-terminus (1-150) shows no similarity, FASTA score: sp|P06862|SERB_ECOLI PHOSPHOSERINE PHOSPHATASE (EC 3.1 (322 aa) opt: 628 z-sc (serB2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3037Rv3043c, (MTV012.58c), len: 573. ctaD. Probable cytochrome c oxidase polypeptide I (EC 1.9.3.1) (CYTOCHROME AA3 SUBUNIT 1), similar to many e.g. Q04440|COX1_BACFI. Contains PS00077 Cytochrome c oxidase subunit I, copper B binding region signature. FASTA score: s (ctaD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3038Rv3044, (MTV012.59), len: 359. Probable fecB, lipoprotein that may be involved in FeIII-dicitrate transport. Similar to many periplasmic FeIII-dicitrate transporters e.gsptr|P72593 (315 aa). Has signal peptide and appropriately positioned PS00013 Prokaryotic me (fecB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3039Rv3045, (MTV012.60), len: 346. adhC. Identical to alcohol dehydrogenase from M. bovis BCG. Contains PS00059 Zinc-containing alcohol dehydrogenases signature. FASTA score: sp|P31975|ADH_MYCBO NADP-DEPENDENT ALCOHOL DEHYDROGENA (346 aa) opt: 2302 z-score: 2682.6 (adhC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3040Rv3046chypothetical protein Rv3046c {Mycobacterium tuberculosis H37Rv (lab strain)}
3041Rv3047chypothetical protein Rv3047c {Mycobacterium tuberculosis H37Rv (lab strain)}
3042Rv3048c, (MTV012.63c), len: 324. nrdG. Identical to M. tuberculosis RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE 2 BETA CHAIN (EC 1.17.4.1). Also very similar to second M. tuberculosis enzyme MTCY39.38 Q10840|RIR2_MYCTU. Contains PS00368 Ribonucleotide reductase small s (nrdG) {Mycobacterium tuberculosis H37Rv (lab strain)}
3043Rv3049chypothetical protein Rv3049c {Mycobacterium tuberculosis H37Rv (lab strain)}
3044Rv3050chypothetical protein Rv3050c {Mycobacterium tuberculosis H37Rv (lab strain)}
3045Rv3051c, (MTV012.66c), len: 693. nrdE, ribonucleotide-diphosphate reductase alpha chain nearly identical to P50640|RIR1_MYCTU. Contains PS00089 Ribonucleotide reductase large subunit signature and is continuation of MTCY22D7.31.FASTA score: sp|P50640|RIR1_MYCTU (nrdE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3046Rv3052c, (MTCY22D7.30), len: 150. nrdI. Probable nrdI protein, similar to many e.g. sp|Q47415|NRDI_ECOLI NRDI PROTEIN (136 aa) fasta scores, opt: 574 z-score: 747.2 E(): 0; 62.2% identity in 135 aa overlap (nrdI) {Mycobacterium tuberculosis H37Rv (lab strain)}
3047Rv3053c, (MTCY22D7.29), len: 79. nrdH. Probable NrdH protein, involved in electron transfer, shows strong similarity to other NrdH glutaredoxin-like proteins. FASTA best: sp|Q56108|NRDH_SALTY GLUTAREDOXIN-LIKE PROTEIN NRDH. (81 aa) fatsa scores, opt: 243 z-score (nrdH) {Mycobacterium tuberculosis H37Rv (lab strain)}
3048Rv3054chypothetical protein Rv3054c {Mycobacterium tuberculosis H37Rv (lab strain)}
3049Rv3055hypothetical protein Rv3055 {Mycobacterium tuberculosis H37Rv (lab strain)}
3050Rv3056, (MTCY22D7.25c), len: 346. dinP, extensive similarity to proteins induced by DNA damage such as dinP, mucB, umuC. Also similar to MTCY48.28c. FASTA best: YQJH_BACSU P54545 hypothetical 47.0 kd protein in glnq- (414 aa) opt: 493, E(): 2e-26, (32.9% identi (dinP) {Mycobacterium tuberculosis H37Rv (lab strain)}
3051Rv3057chypothetical protein Rv3057c {Mycobacterium tuberculosis H37Rv (lab strain)}
3052Rv3058chypothetical protein Rv3058c {Mycobacterium tuberculosis H37Rv (lab strain)}
3053Rv3059hypothetical protein Rv3059 {Mycobacterium tuberculosis H37Rv (lab strain)}
3054Rv3060chypothetical protein Rv3060c {Mycobacterium tuberculosis H37Rv (lab strain)}
3055Rv3061c, (MTCY22D7.20), len: 721. fadE22, probable Acyl-CoA Dehydrogenase; extensive similarity in C-terminal half to many acyl-CoA dehydrogenases. Related to many others in M. tuberculosis e.g. MTCY03C7.13, and MTCY10D7.02. FASTA: G47382 acyl-CoA dehydrogenase (fadE22) {Mycobacterium tuberculosis H37Rv (lab strain)}
3056Rv3062, (MTCY22D7.19c), len: 507. ligB. Probable DNA ligase, highly similar to numerous archaebacterial and eukaryotic polynucleotide ligases. Similarity at N-terminus is poor so first start codon was taken. Contains ATP-dependent DNA ligase AMP-binding site si (ligB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3057Rv3063, (MTCY22D7.18c), len: 758. Function: cstA, probable starvation-induced stress response protein, similarto several. Predicted to be membrane associated. Similaritysuggests start at GTG at 16801 in Y22D7 but no RBS obviousso TBparse-predicted start at 1688 (cstA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3058Rv3064chypothetical protein Rv3064c {Mycobacterium tuberculosis H37Rv (lab strain)}
3059Rv3065, (MTCY22D7.17c), len: 107. emrE. Function: Membrane protein highly similar to bacterial proteins involved in resistance to ethidium bromide or methyl viologen. Also similar to the SugE protein of enteric bacteria. FASTA: SW:P23895 EMRE_ECOLI EMRE protein (emrE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3060Rv3066hypothetical protein Rv3066 {Mycobacterium tuberculosis H37Rv (lab strain)}
3061Rv3067hypothetical protein Rv3067 {Mycobacterium tuberculosis H37Rv (lab strain)}
3062Rv3068c, (MTCY22D7.13), len: 547. Probable pgm: phosphoglucomutase highly similar to many other phosphoglucomutases and phosphomannomutases. Has phosphoglucomutase and phosphomannomutase signature (PS00710) and ATP/GTP-binding site motif A (P-loop),(PS00017), FA (pgmA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3063Rv3069hypothetical protein Rv3069 {Mycobacterium tuberculosis H37Rv (lab strain)}
3064Rv3070hypothetical protein Rv3070 {Mycobacterium tuberculosis H37Rv (lab strain)}
3065Rv3071hypothetical protein Rv3071 {Mycobacterium tuberculosis H37Rv (lab strain)}
3066Rv3072chypothetical protein Rv3072c {Mycobacterium tuberculosis H37Rv (lab strain)}
3067Rv3073chypothetical protein Rv3073c {Mycobacterium tuberculosis H37Rv (lab strain)}
3068Rv3074hypothetical protein Rv3074 {Mycobacterium tuberculosis H37Rv (lab strain)}
3069Rv3075chypothetical protein Rv3075c {Mycobacterium tuberculosis H37Rv (lab strain)}
3070Rv3076hypothetical protein Rv3076 {Mycobacterium tuberculosis H37Rv (lab strain)}
3071Rv3077, (MTCY22D7.04c), len: 603. atsF, some similarity to variety of aryl- and steryl sulfatases. FASTA best: G1177864 PHOSPHONATE MONOESTER HYDROLASE (514 aa) opt: 239 z-score: 265.5 E(): 8.4e-08. (24.0% identity in 413 aa overlap). TBparse score is 1.002 (atsF) {Mycobacterium tuberculosis H37Rv (lab strain)}
3072Rv3078hypothetical protein Rv3078 {Mycobacterium tuberculosis H37Rv (lab strain)}
3073Rv3079chypothetical protein Rv3079c {Mycobacterium tuberculosis H37Rv (lab strain)}
3074Rv3080c, (MTV013.01c-MTCY22D7.01), len: 1110. pknK.Probable serine-threonine protein kinase, similar to several in N-terminal half. C-terminal part from aa 300 related to N-terminal parts of Klebsiella pneumoniae CG43 aco operon regulatory protein ACOK (921 aa) (pknK) {Mycobacterium tuberculosis H37Rv (lab strain)}
3075Rv3081hypothetical protein Rv3081 {Mycobacterium tuberculosis H37Rv (lab strain)}
3076Rv3082c, (MTV013.03c), len: 340. Almost identical to putative 38 kD virulence regulating protein of M. tuberculosis H37Rv described in GENE 126:157-158(1993). Member of ARAC/XYLS FAMILY. Has potential helix-turn-helix motif at positions 252-273. Some similarity (virS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3077Rv3083hypothetical protein Rv3083 {Mycobacterium tuberculosis H37Rv (lab strain)}
3078Rv3084, (MTV013.05), len: 308. Unknown but similar to ACETYL-HYDROLASE (EC 3.1.1.-) and various esterases. FASTA scores: sp|Q01109|BAH_STRHY ACETYL-HYDROLASE (EC 3.1.1.-). (299 aa) opt: 558 z-score: 654.3 E(): 5.9e-29; (40.2% identity in 246 aa overlap). Also s (lipR) {Mycobacterium tuberculosis H37Rv (lab strain)}
3079Rv3085hypothetical protein Rv3085 {Mycobacterium tuberculosis H37Rv (lab strain)}
3080Rv3086, (MTV013.07), len: 368. adhD. Probable alcohol dehydrogenase similar to many especially MTCY369.06c. Contains PS00059 Zinc-containing alcohol dehydrogenases signature. FASTA scores: gp|Z80226|MTCY369_6 Mycobacterium tuberculosis cosmid (375 aa) opt: 1186 (adhD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3081Rv3087hypothetical protein Rv3087 {Mycobacterium tuberculosis H37Rv (lab strain)}
3082Rv3088hypothetical protein Rv3088 {Mycobacterium tuberculosis H37Rv (lab strain)}
3083Rv3089, (MTV013.10), len: 503. fadD13, Acyl-CoA Synthetase similar to many e.g. MTCI28.06, MTCY08D5.09, MTCY06G11.08, and to OSB-CoA synthase from B. subtilis. Contains PS00455 Putative AMP-binding domain signature and PS00061 Short-chain alcohol dehydrogenase (fadD13) {Mycobacterium tuberculosis H37Rv (lab strain)}
3084Rv3090hypothetical protein Rv3090 {Mycobacterium tuberculosis H37Rv (lab strain)}
3085Rv3091hypothetical protein Rv3091 {Mycobacterium tuberculosis H37Rv (lab strain)}
3086Rv3092chypothetical protein Rv3092c {Mycobacterium tuberculosis H37Rv (lab strain)}
3087Rv3093chypothetical protein Rv3093c {Mycobacterium tuberculosis H37Rv (lab strain)}
3088Rv3094chypothetical protein Rv3094c {Mycobacterium tuberculosis H37Rv (lab strain)}
3089Rv3095hypothetical protein Rv3095 {Mycobacterium tuberculosis H37Rv (lab strain)}
3090Rv3096hypothetical protein Rv3096 {Mycobacterium tuberculosis H37Rv (lab strain)}
3091Rv3097c, (MTCY164.08c), len: 436. Esterase/lipase, identical to TR:P77909 (EMBL:U76006) ESTERASE/LIPASE (EC 3.1.1.3) (TRIACYLGLYCEROL LIPASE) (437 aa); N-terminal similar to N-terminal of M. tuberculosis PE family members, eg Y03A_MYCTU Q10637 hypothetical glyci (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3092Rv3098chypothetical protein Rv3098c {Mycobacterium tuberculosis H37Rv (lab strain)}
3093Rv3099chypothetical protein Rv3099c {Mycobacterium tuberculosis H37Rv (lab strain)}
3094Rv3100c, (MTCY164.11c), len: 160. smpB. Probable small protein b related to several bacterial small protein b homologs e.g. SMPB_ENTFA P43659 small protein b homolog. Enterococcus faecalis (163 aa). FASTA results opt: 473, E():7.7e-26; (45.6% identity in 147 aa (smpB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3095Rv3101c, (MTCY164.12c), ftsX, len: 297, membrane protein possibly FtsX, similar to FTSX_HAEIN P44872 cell division protein FtsX homolog (310 aa), fasta results, opt: 196E(): 3.9e-06; (20.6% identity in 243 aa overlap) (ftsX) {Mycobacterium tuberculosis H37Rv (lab strain)}
3096Rv3102c, (MTCY164.13_2c), len: 229. ftsE. Probable cell division ATP-binding protein, similar to FTSE_ECOLI P10115 (222 aa). FASTA, opt: 649, E(): 5.2e-35; 49.1% identity in 216 aa overlap. Contains ATP/GTP-binding site motif A(P-loop; PS00017) and ABC transport (ftsE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3097Rv3103chypothetical protein Rv3103c {Mycobacterium tuberculosis H37Rv (lab strain)}
3098Rv3104chypothetical protein Rv3104c {Mycobacterium tuberculosis H37Rv (lab strain)}
3099Rv3105c, (MTCY164.15c), len: 378. prfB. Probable peptide chain release factor 2, strong similarity to M. leprae sp|O32885|O32885 PEPTIDE CHAIN RELEASE FACTOR 2 (374 aa) opt: 2197 z-score: 2444.0 E(): 0; 90.1% identityin 372 aa overlap and RF2_SALTY P28353 (365 a (prfB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3100Rv3106, (MTCY164.16), len: 456. fprA. Probable adrenodoxin and NADPH ferredoxin reductase, similar to several. FASTA, E241991 HYPOTHETICAL 61.3 KD PROTEIN (575 aa) opt:894; E(): 0; (42.0% identity in 459 aa overlap). Very similar to MTCY31.14, E(): 0; (42.0% id (fprA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3101Rv3107chypothetical protein Rv3107c {Mycobacterium tuberculosis H37Rv (lab strain)}
3102Rv3108hypothetical protein Rv3108 {Mycobacterium tuberculosis H37Rv (lab strain)}
3103Rv3109, (MTCY164.19), len: 359. moaA. Highly similar to the NarA and MoaA proteins, may be involved in molybdo-pterin synthesis. FASTA, NARA_BACSU P39757 NarA protein. Bacillus subtilis (341 aa) opt: 810; E(): 0; 39.8% identity in 327 aa overlap. Also similar t (moaA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3104Rv3110, (MTCY164.20), len: 131. moaB. Probably involved in molybdopterin synthesis. FASTA results: PHS_HUMAN P80095 pterin-4-alpha-carbinolamine dehydratase (103 aa) opt: 132; E(): 0.011; 31.9% identity in 94 aa overlap (moaB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3105Rv3111, (MTCY164.21), len: 170. moaC. Probably involved in molybdopterin synthesis. FASTA results: MOAC_HAEIN P45310 molybdenum cofactor biosynthesis prot (160 aa) opt: 512; E(): 2.9e-27; 58.0% identity in 150 aa overlap (moaC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3106Rv3112, (MTCY164.22), len: 83. moaD. Probable MoaD involved in molybdopterin synthesis. FASTA, P30748|MOAD_ECOLI MOLYBDOPTERIN CONVERTING ENZYME(81 aa) opt: 125; E(): 0.0011; 37.8% identity in 82 aa overlap (moaD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3107Rv3113hypothetical protein Rv3113 {Mycobacterium tuberculosis H37Rv (lab strain)}
3108Rv3114hypothetical protein Rv3114 {Mycobacterium tuberculosis H37Rv (lab strain)}
3109Rv3115hypothetical protein Rv3115 {Mycobacterium tuberculosis H37Rv (lab strain)}
3110Rv3116, (MTCY164.26), len: 389. moeB. Probably involved in molybdopterin metabolism, very similar to members of the HESA/MOEB/THIF family. FASTA results, YCXH_PORPU P51335 hypothetical 43.4 kd protein opt: 743 z-score: 869.0 E(): 0; (35.5% identity in 375 aa ov (moeB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3111Rv3117, (MTCY164.27), len: 277. cysA3. Probable thiosulfate sulfurtransferase. Very similar to CysA of M. leprae and putative thiosulfate sulfurtransferases. Contains rhodanese active site and C-terminal signatures (PS00380, PS00683). FASTA results, G699218 CYS (cysA3) {Mycobacterium tuberculosis H37Rv (lab strain)}
3112Rv3118, (MTCY164.28), len: 100. Unknown but very similar to hypothetical M. leprae protein G699208 U2266J (143aa) and to Saccharopolyspora erythraea sp|Q54084 (HYPOTHETICAL 10.2 KD PROTEIN). FASTA results, opt: 545 E(): 2.1e-31;(84.0% identity in 100 aa overlap (sseC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3113Rv3119, (MTCY164.29), len: 147. moaE. Probable molybdopterin converting factor E. Very similar to molybdopterin converting factors E of E. coli and H. influenzae. FASTA results MOAE_HAEIN P45308 , opt: 323; E(): 6.6e-16; 38.2% identity in 131 aa overlap (moaE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3114Rv3120hypothetical protein Rv3120 {Mycobacterium tuberculosis H37Rv (lab strain)}
3115Rv3121hypothetical protein Rv3121 {Mycobacterium tuberculosis H37Rv (lab strain)}
3116Rv3122hypothetical protein Rv3122 {Mycobacterium tuberculosis H37Rv (lab strain)}
3117Rv3123hypothetical protein Rv3123 {Mycobacterium tuberculosis H37Rv (lab strain)}
3118Rv3124hypothetical protein Rv3124 {Mycobacterium tuberculosis H37Rv (lab strain)}
3119Rv3125c, (MTCY164.35c), len: 391. Member of M. tuberculosis PPE family, FASTA results, Y07P_MYCTU Q11031 hypothetical 40.0 kd protein cy02b10.25c (396 aa) opt: 703; E():1.2e-30; (38.6% identity in 383 aa overlap). Other examplesare MTCY98.0029c, E(): 0; MTCY03A2 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3120Rv3126chypothetical protein Rv3126c {Mycobacterium tuberculosis H37Rv (lab strain)}
3121Rv3127hypothetical protein Rv3127 {Mycobacterium tuberculosis H37Rv (lab strain)}
3122Rv3129hypothetical protein Rv3129 {Mycobacterium tuberculosis H37Rv (lab strain)}
3123Rv3130chypothetical protein Rv3130c {Mycobacterium tuberculosis H37Rv (lab strain)}
3124Rv3131hypothetical protein Rv3131 {Mycobacterium tuberculosis H37Rv (lab strain)}
3125Rv3132chypothetical protein Rv3132c {Mycobacterium tuberculosis H37Rv (lab strain)}
3126Rv3133chypothetical protein Rv3133c {Mycobacterium tuberculosis H37Rv (lab strain)}
3127Rv3134chypothetical protein Rv3134c {Mycobacterium tuberculosis H37Rv (lab strain)}
3128Rv3135, (MTCY03A2.23c), len: 132, unknown, PPE family member of Mycobacterium tuberculosis Ala-, Gly-rich PPE family, similar to MTCY3A2_22 (next ORF downstream), MTY21C12_9, MTCY3C7_24, MTCI125_27, MTV049_12, MTV049_9, MTV049_11, MTCY274_24 etc. YX23_MYCTU Q10 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3129Rv3136, (MTCY03A2.22c), len: 380, unknown, PPE-FAMILY PROTEIN,Gly-Ala-rich family, similar to MTV002_36, MTCI125_26, MTCY10G2_10, MTCI364_8, MTV049_28, MTV049_29, etc. FASTA scores: O33312 PPE-FAMILY PROTEIN, opt: 917 z-score: 858.7 E(): 0; 46.1% identity in 38 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3130Rv3137hypothetical protein Rv3137 {Mycobacterium tuberculosis H37Rv (lab strain)}
3131Rv3138, (MTCY03A2.20c), len: 362, PROBABLE PYRUVATEFORMATE LYASE ACTIVATING PROTEIN, similar to many, e.g. AE000902_6 Methanobacterium thermoautotrop (335 aa), FASTA scores: opt: 909 z-score: 1081.0 E(): 0; (42.2% identity in 327 aa overlap), TBparse score is 0 (pflA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3132Rv3139, (MTCY03A2.19c), len: 468, fadE24, probable acyl-CoA dehydrogenase, equivalent to MLCB1779_20 Mycobacterium leprae O32890 HYPOTHETICAL 49.8 KD PROTEIN (83.6% identity in 464 aa overlap). Contains acyl-CoA dehydrogenases signature 2 (PS00073) near C-termi (fadE24) {Mycobacterium tuberculosis H37Rv (lab strain)}
3133Rv3140, (MTCY03A2.18c), len: 401.fadE23, PUTATIVE ACYL-COA DEHYDROGENASE, similar to ACDS_HUMAN P16219 acyl-CoA dehydrogenase, short-chain (412 aa), FASTA scores: opt:575, E(): 6.4e-30, (31.2% identity in 394 aa overlap). EQUIVALENT to MLCB1779_21 Mycobacterium (fadE23) {Mycobacterium tuberculosis H37Rv (lab strain)}
3134Rv3141, (MTCY03A2.17c), len: 323, fadB4, probable quinone oxidoreductase showing strong similarity to varietyof quinone oxidoreductases and domains in polyketide and fatty acid synthases. Also resembles: MTCI5_23, MTCY13D12.11,MTCY24G1.03, MTCY19H9.01. FASTA: Q (fadB4) {Mycobacterium tuberculosis H37Rv (lab strain)}
3135Rv3142chypothetical protein Rv3142c {Mycobacterium tuberculosis H37Rv (lab strain)}
3136Rv3143hypothetical protein Rv3143 {Mycobacterium tuberculosis H37Rv (lab strain)}
3137Rv3144c, (MTCY03A2.14), len: 409 aa. PPE family protein, Gly-, Ala-rich, similar to MTCY03C7.23, MTV014_3, MTCY6G11_5, MTCY98.0034c, MTCY31.06c, MTCY48.17, MTCY98.0029c, MTCY03C7.17c, etc. TBparse score is 0.891 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3138Rv3145, (MTCY03A2.13c), len: 108, nuoA, transmembrane NADH dehydrogenase subunit. FASTA best: WHTCPPSBG_1 Triticum aestivum chloropla NU3C_WHEAT P26303 nadh-plastoquinone oxidoreductase (120 aa) opt: 273, E(): 3.3e-12, (38.3% identity in 128 aa overla), TBparse (nuoA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3139Rv3146, (MTCY03A2.12c), len: 184, nuoB, NADH dehydrogenase subunit. FASTA best: sp|Q56218|NQO6_THETH NADH dehydrogenase I,subunit NQO6 (181 aa), opt: 720, E(): 0, (64.5%identity in 152 aa overlap), TBparse score is 0.912 (nuoB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3140Rv3147, (MTCY03A2.11c), len: 236, nuoC, NADH dehydrogenase subunit. FASTA best: NUGM_CANMA Q00673 probable nadh-ubiquinone oxidoreductase (276 aa) opt: 333, E(): 4.1e-15; (36.3% identity in 135 aa overlap),Also similar to MTCY251.05, 4.9e-05. TBparse score is 0 (nuoC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3141Rv3148, (MTCY03A2.10c), len: 440, nuoD, NADH dehydrogenase subunit. Some similarity to MTCY251.05, 1e-12. FASTA best: NUCM_PARTE P15689 nadh-ubiquinone oxidoreductase 49kd (400 aa), opt: 922, E(): 0; (38.5% identity in 408 aa overlap). Contains helix-turn-helix (nuoD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3142Rv3149, (MTCY03A2.09c), len: 252, nuoE, NADH dehydrogenase subunit. FASTA best: SW:P19234 NUHM_RAT NADH-ubiquinone dehydrogenase 24 kDa protein, fasta scores, opt: 360 (31.6% identity in 231 aa overlap) (nuoE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3143Rv3150, (MTCY03A2.08c), len: 445, nuoF, NADH dehydrogenase subunit, contains respiratory-chain NADH dehydrogenase 51 Kd subunit signature 2 (PS00645). FASTA best: NUOF_ECOLI P31979 nadh dehydrogenase i chain f (445 aa), opt: 1365, E(): 0, (47.1% identity in 442 (nuoF) {Mycobacterium tuberculosis H37Rv (lab strain)}
3144Rv3151, (MTCY03A2.07c), len: 806, nuoG, NADH dehydogenase subunit contains respiratory-chain NADH dehydrogenase 75 Kd subunit signature 2 (PS00642). FASTA scores: e.g. NEUNDS_1 Neurospora crassa Q01388 NADH dehydrogenase subunit (744 aa) opt: 885, E(): 0, (29.8 (nuoG) {Mycobacterium tuberculosis H37Rv (lab strain)}
3145Rv3152, (MTCY03A2.06c), len: 410, nuoH, transmembrane subunit of NADH dehydrogenase contains respiratory-chainNADH dehydrogenase subunit 1 signature 2 ( PS00668). Some similarity to MTCY251.02 (1.2e-07). FASTA best: NUOH_RHOCA P42032 nadh dehydrogenase i chain (nuoH) {Mycobacterium tuberculosis H37Rv (lab strain)}
3146Rv3153, (MTCY03A2.05c), len: 211, NuoI, iron-sulfurprotein component of NADH dehydrogenase contains two 4Fe-4Sferredoxins, iron-sulfur binding region signatures (PS00198). FASTA best: sp|Q56224|NQO9_THETH NADH-UBIQUINONE OXIDOREDUCTASE , subunit, NQO9 (182 aa), (nuoI) {Mycobacterium tuberculosis H37Rv (lab strain)}
3147Rv3154, (MTCY03A2.04c), len: 262, NuoJ, NADH dehydrogenase transmembrane subunit. FASTA best: NU6C_PLEBO Q00243 nadh-plastoquinone oxidoreductase cha (199 aa) initn: 231 init1: 160 opt: 287 z-score: 336.8 E(): 8.9e-12; 34.4% identity in 195 aa overlap. TBparse (nuoJ) {Mycobacterium tuberculosis H37Rv (lab strain)}
3148Rv3155, (MTCY03A2.03c), len: 99, nuoK, NADH dehydrogenase subunit, transmembrane protein. . FASTA best: sp|Q56226|NQOB_THETH NADH-UBIQUINONE OXIDOREDUCTASE NADH dehydrogenase I, subunitNQO11, (95 aa) opt: 313, E(): 7e-20; (53.7%identity in 95 aa overlap), TBpar (nuoK) {Mycobacterium tuberculosis H37Rv (lab strain)}
3149Rv3156, (MTCY03A2.02c), len: 633, nuoL, NADH dehydrogenase transmembrane subunit. Also similar to MTCY251.04 (1.3e-11) and MTCY03A2.01c (2.3e-10). FASTA best: sp|Q56227|NQOC_THETH NADH-UBIQUINONE OXIDOREDUCTASE NADH dehydrogenase I, subunit NQO12, (606 aa), opt (nuoL) {Mycobacterium tuberculosis H37Rv (lab strain)}
3150Rv3157, (MTCY03A2.01c-MTV014.01c), len: 553, nuoM, NADH dehydrogenase subunit. Similar to MTCY251.04 (3.3e-16) and MTCY03A2.02c (9.6e-13). FASTA best: NUOM_RHOCA P50974nadh dehydrogenase I chain (512 aa) opt: 996 z-score: 1165.2 E(): 0; 38.3% identity in 522 aa (nuoM) {Mycobacterium tuberculosis H37Rv (lab strain)}
3151Rv3158, (MTV014.02c), len: 531, nuoN, probable NADHdehydrogenase (EC1.6.5.3) N subunit (integral membrane protein) similar to many and to Synechococcus sp. NdhB (521 aa)NADH dehydrogenase subunit II (EC1.6.99.3). FASTA scores:X65027|S7942NDHB_1 Synechococcus sp (nuoN) {Mycobacterium tuberculosis H37Rv (lab strain)}
3152Rv3159c, (MTV014.03c), len: 590. Member of M. tuberculosis PPE_family of Gly-, Asn-rich proteins. Highly similar to MTCY03C7.23 (582 aa). FASTA scores: sptr|P71868|P71868 HYPOTHETICAL 55.5 KD PROTEIN (582 aa) opt: 2289 z-score: 1832.6 E(): 0; 63.5% identity in 6 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3153Rv3160chypothetical protein Rv3160c {Mycobacterium tuberculosis H37Rv (lab strain)}
3154Rv3161chypothetical protein Rv3161c {Mycobacterium tuberculosis H37Rv (lab strain)}
3155Rv3162chypothetical protein Rv3162c {Mycobacterium tuberculosis H37Rv (lab strain)}
3156Rv3163chypothetical protein Rv3163c {Mycobacterium tuberculosis H37Rv (lab strain)}
3157Rv3164c, (MTV014.08c), len: 320. Probable regulatory protein similar to many espescially Archaeoglobus fulgidus MoxR (324 aa; putative methanol dehydrogenase regulatory protein) and B. subtilis YEAC (320 aa). FASTA scores: gp|AE0011|AE001108_1 Archaeoglobus fulg (moxR3) {Mycobacterium tuberculosis H37Rv (lab strain)}
3158Rv3165chypothetical protein Rv3165c {Mycobacterium tuberculosis H37Rv (lab strain)}
3159Rv3166chypothetical protein Rv3166c {Mycobacterium tuberculosis H37Rv (lab strain)}
3160Rv3167chypothetical protein Rv3167c {Mycobacterium tuberculosis H37Rv (lab strain)}
3161Rv3168hypothetical protein Rv3168 {Mycobacterium tuberculosis H37Rv (lab strain)}
3162Rv3169hypothetical protein Rv3169 {Mycobacterium tuberculosis H37Rv (lab strain)}
3163Rv3170hypothetical protein Rv3170 {Mycobacterium tuberculosis H37Rv (lab strain)}
3164Rv3171c, (MTV014.15c), len: 299. hpx, some similarity to variety of non-heme haloperoxidases e.g.P49323 (275 aa). Start chosen by similarity, alternative with good RBS possible. FASTA scores: sp|P49323|PRXC_STRLI NON-HEME CHLOROPEROXIDASE (EC 1.1 (275 aa) opt: 2 (hpx) {Mycobacterium tuberculosis H37Rv (lab strain)}
3165Rv3172chypothetical protein Rv3172c {Mycobacterium tuberculosis H37Rv (lab strain)}
3166Rv3173chypothetical protein Rv3173c {Mycobacterium tuberculosis H37Rv (lab strain)}
3167Rv3174hypothetical protein Rv3174 {Mycobacterium tuberculosis H37Rv (lab strain)}
3168Rv3175hypothetical protein Rv3175 {Mycobacterium tuberculosis H37Rv (lab strain)}
3169Rv3176c, (MTV014.20c), len: 318. Unknown but similar to several M. tuberculosis proteins e.g. MTCY1A11.09C (288 aa) that show similarity to esterases/lipases/epoxide hydrolase. FASTA scoressp|Q50599|Y0D9_MYCTU HYPOTHETICAL 31.7 KD PROTEIN (288 aa) opt: 294 z-sco (lipS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3170Rv3177hypothetical protein Rv3177 {Mycobacterium tuberculosis H37Rv (lab strain)}
3171Rv3178hypothetical protein Rv3178 {Mycobacterium tuberculosis H37Rv (lab strain)}
3172Rv3179hypothetical protein Rv3179 {Mycobacterium tuberculosis H37Rv (lab strain)}
3173Rv3180chypothetical protein Rv3180c {Mycobacterium tuberculosis H37Rv (lab strain)}
3174Rv3181chypothetical protein Rv3181c {Mycobacterium tuberculosis H37Rv (lab strain)}
3175Rv3182hypothetical protein Rv3182 {Mycobacterium tuberculosis H37Rv (lab strain)}
3176Rv3183hypothetical protein Rv3183 {Mycobacterium tuberculosis H37Rv (lab strain)}
3177Rv3184hypothetical protein Rv3184 {Mycobacterium tuberculosis H37Rv (lab strain)}
3178Rv3185hypothetical protein Rv3185 {Mycobacterium tuberculosis H37Rv (lab strain)}
3179Rv3186hypothetical protein Rv3186 {Mycobacterium tuberculosis H37Rv (lab strain)}
3180Rv3187hypothetical protein Rv3187 {Mycobacterium tuberculosis H37Rv (lab strain)}
3181Rv3188hypothetical protein Rv3188 {Mycobacterium tuberculosis H37Rv (lab strain)}
3182Rv3189hypothetical protein Rv3189 {Mycobacterium tuberculosis H37Rv (lab strain)}
3183Rv3190chypothetical protein Rv3190c {Mycobacterium tuberculosis H37Rv (lab strain)}
3184Rv3191chypothetical protein Rv3191c {Mycobacterium tuberculosis H37Rv (lab strain)}
3185Rv3192hypothetical protein Rv3192 {Mycobacterium tuberculosis H37Rv (lab strain)}
3186Rv3193chypothetical protein Rv3193c {Mycobacterium tuberculosis H37Rv (lab strain)}
3187Rv3194chypothetical protein Rv3194c {Mycobacterium tuberculosis H37Rv (lab strain)}
3188Rv3195hypothetical protein Rv3195 {Mycobacterium tuberculosis H37Rv (lab strain)}
3189Rv3196hypothetical protein Rv3196 {Mycobacterium tuberculosis H37Rv (lab strain)}
3190Rv3197hypothetical protein Rv3197 {Mycobacterium tuberculosis H37Rv (lab strain)}
3191Rv3198c, (MTV014.42c), uvrD, len: 700. Probable UvrD similar to several, especially the products of two adjacent orfs in M. leprae B1937_F1_27 (P53528) and B1937_F1_26 (Q49764).Also very similar to Mycobacterium tuberculosis protein MTCY10D7_25 (771 aa). Contain (uvrD2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3192Rv3199chypothetical protein Rv3199c {Mycobacterium tuberculosis H37Rv (lab strain)}
3193Rv3200chypothetical protein Rv3200c {Mycobacterium tuberculosis H37Rv (lab strain)}
3194Rv3201chypothetical protein Rv3201c {Mycobacterium tuberculosis H37Rv (lab strain)}
3195Rv3202chypothetical protein Rv3202c {Mycobacterium tuberculosis H37Rv (lab strain)}
3196Rv3203, (MTCY07D11.23c), len: 224, unknown but shows some similarity to lipases and contains serine active site signature of lipases (PS00120). FASTA best: P19076 DMPD_PSEPU 2-HYDROXYMUCONIC SEMIALDEHYDE hydrolase (283 aa) opt:171 z-score: 201.7 E(): 0.00012; ( (lipV) {Mycobacterium tuberculosis H37Rv (lab strain)}
3197Rv3204hypothetical protein Rv3204 {Mycobacterium tuberculosis H37Rv (lab strain)}
3198Rv3205chypothetical protein Rv3205c {Mycobacterium tuberculosis H37Rv (lab strain)}
3199Rv3206c, (MTCY07D11.20), len: 392. probable MOEB- homolog, possibly involved in cofactor synthesis, shows goodsimilarity to enzymes involved in molbdopterin synthesis. Has hydrophobic segment from 45-71, and belongs to the HesA/MoeB/ThiF family. FASTA best: P513 (moeZ) {Mycobacterium tuberculosis H37Rv (lab strain)}
3200Rv3207chypothetical protein Rv3207c {Mycobacterium tuberculosis H37Rv (lab strain)}
3201Rv3208hypothetical protein Rv3208 {Mycobacterium tuberculosis H37Rv (lab strain)}
3202Rv3209hypothetical protein Rv3209 {Mycobacterium tuberculosis H37Rv (lab strain)}
3203Rv3210chypothetical protein Rv3210c {Mycobacterium tuberculosis H37Rv (lab strain)}
3204Rv3211, (MTCY07D11.15c), len: 524, probable ATP-dependent RNA helicase. Contains ATP/GTP-binding site motif A; (PS00017) and DEAD-box subfamily ATP-dependent helicases signature (PS00039). Extensive similarity with MTCY50.29c, E: 2.5e-35. FASTA best: P33906 DEA (rhlE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3205Rv3212hypothetical protein Rv3212 {Mycobacterium tuberculosis H37Rv (lab strain)}
3206Rv3213chypothetical protein Rv3213c {Mycobacterium tuberculosis H37Rv (lab strain)}
3207Rv3214, (MTCY07D11.12c), len: 203, entD, shows weaksimilarity to many PHOSPHOGLYCERATE MUTASES. Some similarity at N-terminus with other M. tuberculosis proteins. MTCY427.09c, MTCY20G9.15, MTCY428.28. FASTA best: Q10512 Y019_MYCTU HYPOTHETICAL 39.2 kDa protein (entD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3208Rv3215, (MTCY07D11.11c), len: 372, entC, probable isochorismate synthase (EC 5.4.99.6) could be involved in enterochelin or menaquinone biosynthesis. Stronger similarityto E. coli entC suggests former. Also similar to MTCY253.35. FASTA best: P45744 DHBC_BACSU I (entC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3209Rv3216hypothetical protein Rv3216 {Mycobacterium tuberculosis H37Rv (lab strain)}
3210Rv3217chypothetical protein Rv3217c {Mycobacterium tuberculosis H37Rv (lab strain)}
3211Rv3218hypothetical protein Rv3218 {Mycobacterium tuberculosis H37Rv (lab strain)}
3212Rv3219, (MTCY07D11.07c), len: 84, whiB-homolog, putative regulatory protein, similar to MTCY78_13. FASTA best: SCWHIB_1 S;coelicolor whiB gene; Regulatory (87 aa, E(): 7e-10;43.8% identity in 73 aa overlap. Also similar to U00020_2 Mycobacterium leprae cosmid B (whiB1) {Mycobacterium tuberculosis H37Rv (lab strain)}
3213Rv3220chypothetical protein Rv3220c {Mycobacterium tuberculosis H37Rv (lab strain)}
3214Rv3221AM. tuberculosis H37Rv|Rv3221A|Rv3221A: 101 aa - POSSIBLE ANTI-SIGMA FACTOR
3215Rv3221chypothetical protein Rv3221c {Mycobacterium tuberculosis H37Rv (lab strain)}
3216Rv3222chypothetical protein Rv3222c {Mycobacterium tuberculosis H37Rv (lab strain)}
3217Rv3223c, (MTCY07D11.03), len: 216. sigH, probable RNA polymerase sigma factor, has sigma-70 factors ECF subfamily signature (PS01063). Start chosen on basis of similarity, other potential starts upstream. FASTA best: Q06198 RPSH_PSEAE RNA POLYMERASE SIGMA-H FACT (sigH) {Mycobacterium tuberculosis H37Rv (lab strain)}
3218Rv3224hypothetical protein Rv3224 {Mycobacterium tuberculosis H37Rv (lab strain)}
3219Rv3225chypothetical protein Rv3225c {Mycobacterium tuberculosis H37Rv (lab strain)}
3220Rv3226chypothetical protein Rv3226c {Mycobacterium tuberculosis H37Rv (lab strain)}
3221Rv3227, (MTCY20B11.02), len: 450, AroA, 3-phosphoshikimate 1-carboxyvinyl transferase (EC 2.5.1.19; 5-enolpyruvylshikimate-3-phosphate synthase). FASTA best: M62708|MSGARO_1, AROA_MYCTU; contains PS00885 EPSP synthase signature 2 (aroA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3222Rv3228hypothetical protein Rv3228 {Mycobacterium tuberculosis H37Rv (lab strain)}
3223Rv3229c, (MTCY20B11.04c), len: 427. Function: desA3, but shows some similarity to desaturases. FASTA best:D90914_112 Synechocystis Q08871 LINOLEOYL-COA DESATURASE (EC 1.14.99.25) (359 aa), opt: 319 z-score: 380.8 E(): 3.2e-14; (25.1% identity in 295 aa overlap) (desA3) {Mycobacterium tuberculosis H37Rv (lab strain)}
3224Rv3230chypothetical protein Rv3230c {Mycobacterium tuberculosis H37Rv (lab strain)}
3225Rv3231chypothetical protein Rv3231c {Mycobacterium tuberculosis H37Rv (lab strain)}
3226Rv3232c, (MTCY20B11.07c), len: 295, unknown, some similarity to TRANSCRIPTIONAL REGULATOR PVDS gp|U12891|PAU12891_5 Pseudomonas aeruginosa P72119 PAO SUBSTRAIN OT684 PYOVERDINE GENE(237 aa), E(): 0;(61.2% identity in 227 aa overlap), start uncertain (pvdS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3227Rv3233chypothetical protein Rv3233c {Mycobacterium tuberculosis H37Rv (lab strain)}
3228Rv3234chypothetical protein Rv3234c {Mycobacterium tuberculosis H37Rv (lab strain)}
3229Rv3235hypothetical protein Rv3235 {Mycobacterium tuberculosis H37Rv (lab strain)}
3230Rv3236c, (MTCY20B11.11c), len: 385, unknown membrane protein showing some similarity to glutathione-regulated potassium-efflux proteins. FASTA best: Q45308 PUTATIVE SPORE GERMINATION APPARATUS protein (386 aa) opt: 354 z-score: 399.0 E(): 3.1e-15; (24.3% identit (kefB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3231Rv3237chypothetical protein Rv3237c {Mycobacterium tuberculosis H37Rv (lab strain)}
3232Rv3238chypothetical protein Rv3238c {Mycobacterium tuberculosis H37Rv (lab strain)}
3233Rv3239chypothetical protein Rv3239c {Mycobacterium tuberculosis H37Rv (lab strain)}
3234Rv3240c, (MTCY20B11.15c), len: 949, secA, preprotein translocase subunit, component of secretion apparatus, similar to MTCY1A11.22c, opt: 1212 z-score: 1150.8 E(): 0; (35.2% identity in 862 aa overlap). FASTA best: SECA_STRLI P55021 preprotein translocase SecA s (secA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3235Rv3241chypothetical protein Rv3241c {Mycobacterium tuberculosis H37Rv (lab strain)}
3236Rv3242chypothetical protein Rv3242c {Mycobacterium tuberculosis H37Rv (lab strain)}
3237Rv3243chypothetical protein Rv3243c {Mycobacterium tuberculosis H37Rv (lab strain)}
3238Rv3244c, (MTCY20B11.19c), len: 583, unknown, possibly lipoprotein as contains appropriately placed lipoprotein signature (PS00013) (lpqB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3239Rv3245c, (MTCY20B11.20c), len: 567. Function: MtrB sensor-like histidine kinase, almost identical to MTU14909_1 Mycobacterium tuberculosis MtrB (567 aa, 99.8% identity in 567 aa overlap); Relatives in M. tuberculosis are: MTCY369.03, 1.5e-22; MTCY20G9.16, 1.9e-1 (mtrB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3240Rv3246c, (MTCY20B11.21c), len: 228, mtrA response regulator, putative transcriptional activator, identical to U01971|MTU01971_1 Mycobacterium tuberculosis H37Rv (225 aa), 100.0% identity in 225 aa overlap), also similar to sp|Q11156|RGX3_MYCTU SENSORY TRANSDUCTI (mtrA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3241Rv3247c, (MTCY20B11.22c), len: 214. Function: unknown, but similar to MPAE000016_12 Mycoplasma pneumoniae P75106|KTHY_MYCPN THYMIDYLATE KINASE (210 aa) FASTA scores: opt: 152 z-score: 197.8 E(): 0.0017; 32.3% identity in 158 aa overlap. Also similar to Q55593 HY (tmk) {Mycobacterium tuberculosis H37Rv (lab strain)}
3242Rv3248c, (MTCY20B11.23c), len: 495, sahH, probable adenosylhomocysteinase has S-adenosyl-L-homocysteine hydrolase signature (PS00739) FASTA best: SAAH_TRIVA P51540 adenosylhomocysteinase (486 aa) opt: 2005 z-score: 2240.0 E(): 0; (62.1% identity in 477 aa overla (sahH) {Mycobacterium tuberculosis H37Rv (lab strain)}
3243Rv3249chypothetical protein Rv3249c {Mycobacterium tuberculosis H37Rv (lab strain)}
3244Rv3250c, (MTCY20B11.25c), len: 60, rubredoxin,, similar to P42453|RUBR_ACICA RUBREDOXIN; contains rubredoxin signature (PS00202), also similar to neighbouring ORF M. tuberculosis RubA (MTCY20B11.26c, 7.3e-11). FASTA best: RUBR_ACICA P42453 rubredoxin (rd). acine (rubB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3245Rv3251c, (MTCY20B11.26c), len: 55. Function: rubredoxin, most similar to X65936|POOCT_3 P;oleovorans; contains rubredoxin signature (PS00202). Similar to neighbouring ORF M. tuberculosis rubB, MTCY20B11.25c, 7.3e-11. FASTA best: RUB2_PSEOL P00272 rubredoxin 2. p (rubA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3246Rv3252chypothetical protein Rv3252c {Mycobacterium tuberculosis H37Rv (lab strain)}
3247Rv3253chypothetical protein Rv3253c {Mycobacterium tuberculosis H37Rv (lab strain)}
3248Rv3254hypothetical protein Rv3254 {Mycobacterium tuberculosis H37Rv (lab strain)}
3249Rv3255c, (MTCY20B11.30c), len: 408, probable mannose-6-phosphate isomerase. FASTA best: MANA_HUMAN P34949 mannose-6-phosphate isomerase (422 aa) opt: 562 z-score: 646.8 E(): 4.9e-29; (32.5% identity in 425 aa overlap) (manA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3250Rv3256chypothetical protein Rv3256c {Mycobacterium tuberculosis H37Rv (lab strain)}
3251Rv3257c, (MTV015.02c), len: 465. Probable phosphomannomutase (EC 5.4.2.8) similar to many e.g.P29955|XANA_XANCP (448 aa), Q01411|CPSG_SALMO (456 aa). FASTA scores: sp|P29955|XANA_XANCP PHOSPHOGLUCOMUTASE (EC 5.4.2.2) (448 aa) opt: 1050 z-score: 1252.3 E(): 0; 41 (pmmA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3252Rv3258chypothetical protein Rv3258c {Mycobacterium tuberculosis H37Rv (lab strain)}
3253Rv3259hypothetical protein Rv3259 {Mycobacterium tuberculosis H37Rv (lab strain)}
3254Rv3260c, (MTV015.05c), len: 89. whiB, Probable regulatory protein very similar to S.griseocarneum WhiB SGWHIB_1 (87 aa) and other Streptomyces and mycobacterial WhiB homologues. Start chosen by homology but orf continues to ATG upstream at 3754. FASTA scores: gp (whiB2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3255Rv3261hypothetical protein Rv3261 {Mycobacterium tuberculosis H37Rv (lab strain)}
3256Rv3262hypothetical protein Rv3262 {Mycobacterium tuberculosis H37Rv (lab strain)}
3257Rv3263hypothetical protein Rv3263 {Mycobacterium tuberculosis H37Rv (lab strain)}
3258Rv3264c, (MTCY71.04c), len: 359, rfbF transferase, similar to MPG1_YEAST P41940 mannose-1-phosphate guanyltransferase (361 aa), fasta scores, opt: 557, E(): 1.9e-27, (28.9% identity in 353 aa overlap), also similar to RBA1_ECOLIP37744, glucose-1-phosphate thymid (rmlA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3259Rv3265c, (MTCY71.05c), len: 301, unknown but similar to YEFJ_ECOLI P36667 hypothetical 31.1 kd protein in gnd-r (264 aa), fasta scores, opt: 253, E(): 9.8e-10, (28.6% identity in 259 aa overlap) (wbbL) {Mycobacterium tuberculosis H37Rv (lab strain)}
3260Rv3266c, (MTCY71.06c), len: 304, rfbD, similar to eg STRL_STRGR P29781 dtdp-4-dehydrorhamnose reductase (304 aa), fasta scores, opt: 788, E(): 0, (47.4% identity in 304 aa overlap) (rmlD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3261Rv3267hypothetical protein Rv3267 {Mycobacterium tuberculosis H37Rv (lab strain)}
3262Rv3268hypothetical protein Rv3268 {Mycobacterium tuberculosis H37Rv (lab strain)}
3263Rv3269hypothetical protein Rv3269 {Mycobacterium tuberculosis H37Rv (lab strain)}
3264Rv3270, (MTCY71.10), len: 718 aa, ctpC, cation transport atpase, similar to eg, E. coli ATCU_ECOLI Q59385 probable copper-transporting atpase 11/9 (834 aa), fasta scores, opt: 1115, E(): 0, (34.8% identity in 730 aa overlap); also similar to MTCY251_11 CTPA_MYC (ctpC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3265Rv3271chypothetical protein Rv3271c {Mycobacterium tuberculosis H37Rv (lab strain)}
3266Rv3272hypothetical protein Rv3272 {Mycobacterium tuberculosis H37Rv (lab strain)}
3267Rv3273hypothetical protein Rv3273 {Mycobacterium tuberculosis H37Rv (lab strain)}
3268Rv3274c, (MTCY71.14c), len: 389,fadE25, highly similar to ACD_MYCLE P46703 acyl-coa dehydrogenase (389 aa), fasta scores, opt: 2394, E(): 0, (92.0% identity in 389 aa overlap); contains PS00072 Acyl-CoA dehydrogenases signature 1, PS00073 Acyl-CoA dehydrogenases (fadE25) {Mycobacterium tuberculosis H37Rv (lab strain)}
3269Rv3275c, (MTCY71.15c), len: 174 aa, purE, highly similar to PUR6_MYCLE P46702 phosphoribosylaminoimidazole carboxylase catalytic subunit (171 aa), fasta scores, opt: 878, E(): 0, (81.5% identity in 168 aa overlap) (purE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3270Rv3276c, (MTCY71.16c), len: 429, purK, highly similar to M. leprae PURK_MYCLE P46701 phosphoribosylaminoimidazole carboxylase atpase subunit (EC 4.1.1.21) (439 aa), fasta scores, opt: 2164, E(): 0, (76.8% identity in 435 aa overlap) (purK) {Mycobacterium tuberculosis H37Rv (lab strain)}
3271Rv3277hypothetical protein Rv3277 {Mycobacterium tuberculosis H37Rv (lab strain)}
3272Rv3278chypothetical protein Rv3278c {Mycobacterium tuberculosis H37Rv (lab strain)}
3273Rv3279c, (MTCY71.19c), len: 266, birA, similar to eg BIRA_ECOLI P06709 bira bifunctional protein (biotin operon repressor) (321 aa), fasta scores, opt: 314, E(): 1.1e-13, (33.7% identity in 249 aa overlap). Lacks BirA h-t-h domain at N-terminus, may simply be bi (birA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3274Rv3280, (MTCY71.20, pccB), len: 548 aa,accD5, PROBABLE PROPIONYL-COA CARBOXYLASE BETA CHAIN, similar to many,e.g. PCCB_MYCLE P53002, (549 aa), fasta scores, opt: 3241,E(): 0, (88.7% identity in 549 aa overlap); similar to MTCY427.28, (43.8% identity in 434 aa o (accD5) {Mycobacterium tuberculosis H37Rv (lab strain)}
3275Rv3281hypothetical protein Rv3281 {Mycobacterium tuberculosis H37Rv (lab strain)}
3276Rv3282hypothetical protein Rv3282 {Mycobacterium tuberculosis H37Rv (lab strain)}
3277Rv3283, (MTCY71.23), len: 297 aa, similar to eg THTR_MYCLE P46700 putative thiosulfate sulfurtransferase (296 aa), fasta scores, opt: 1742, E(): 0, (83.4% identity in 296 aa overlap); contains PS00683 Rhodanese C-terminal signature; some similarity to MTCY339.1 (sseA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3278Rv3284hypothetical protein Rv3284 {Mycobacterium tuberculosis H37Rv (lab strain)}
3279Rv3285, (MTCY71.25), len: 600 aa, accA3, similar toeg BCCA_MYCLE P46392 acetyl-/propionyl-coenzyme a carboxylase alpha chainyl (598 aa), fasta scores, opt: 3501, E(): 0, (88.5% identity in 601 aa overlap); contains PS00867 Carbamoyl-phosphate synthase subdomain (accA3) {Mycobacterium tuberculosis H37Rv (lab strain)}
3280Rv3286c, (MTCY71.26), len: 261, sigF, almost identical to M. tuberculosisMTU41061_1 Q50547, stress response/stationary phase sigma factor f (261 aa). Also similar to U00012_11 Mycobacterium leprae Q49668 RPSB (118 aa, 71.2% identity in 111 aa overlap) Contains p (sigF) {Mycobacterium tuberculosis H37Rv (lab strain)}
3281Rv3287c, (MTCY71.27c), len: 242, usfX, hypotheticalprotein, identical to AF001306_2 Mycobacterium tuberculosisP96892 USFX (100.0% identity in 242 aa overlap). Start chosen by similarity, overlapping end of next ORF. Also similar to M. leprae Q49667 B1308_F3_89 ( (rsbW) {Mycobacterium tuberculosis H37Rv (lab strain)}
3282Rv3288chypothetical protein Rv3288c {Mycobacterium tuberculosis H37Rv (lab strain)}
3283Rv3289chypothetical protein Rv3289c {Mycobacterium tuberculosis H37Rv (lab strain)}
3284Rv3290c, (MTCY71.30), len: 449, lat, similar to LAT_NOCLA Q05174 lysine-epsilon aminotransferase (ec 2. (450 aa), fasta scores, opt: 1702, E(): 0, (60.4% identity in 439aa overlap) (lat) {Mycobacterium tuberculosis H37Rv (lab strain)}
3285Rv3291chypothetical protein Rv3291c {Mycobacterium tuberculosis H37Rv (lab strain)}
3286Rv3292hypothetical protein Rv3292 {Mycobacterium tuberculosis H37Rv (lab strain)}
3287Rv3293, (MTCY71.33), len: 494 aa,aldB, similar to eg DHA1_BACSU P42236 probable aldehyde dehydrogenase ycbd (488 aa), fasta scores, opt: 796, E(): 0, (32.1% identity in 442 aa overlap); contains PS00687 Aldehyde dehydrogenases glutamic acid active site. FASTA b (aldB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3288Rv3294hypothetical protein Rv3294 {Mycobacterium tuberculosis H37Rv (lab strain)}
3289Rv3295hypothetical protein Rv3295 {Mycobacterium tuberculosis H37Rv (lab strain)}
3290Rv3296lhr {Mycobacterium tuberculosis H37Rv (lab strain)}
3291Rv3297, (MTCY71.37), len: 255, nei, most similar toEND8_ECOLI P50465 endonuclease viii (263 aa), fasta scores,opt: 317, E(): 1.4e-14, (28.6% identity in 269 aa overlap),also similar to eg FPG_ECOLI P05523 formamidopyrimidine-dna glycosylase (269 aa), fasta scor (nei) {Mycobacterium tuberculosis H37Rv (lab strain)}
3292Rv3298c, (MTCY71.38c), len: 304 aa, similar to M. leprae Q49658 B1308_F2_43, (302 aa), fasta scores, opt: 1541, E(): 0, (72.0% identity in 300 aa overlap). Possibly esterase or poly(3-hydroxyalkanoate) depolymerases.MTI376.03c Z95972 (280 aa) opt: 519; E(): 1.7e (lpqC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3293Rv3299c, (MTCI418A.01c-MTCY71.39c), len: 970, atsB,probable sulfatase similar to eg. ARS_PSEAE P51691 arylsulfatase (ec 3.1.6.1) (532 aa), fasta scores; opt: 624 z-score: 684.8 E(): 4e-31, 31.4% identity in 548 aa overlap. Contains PS00523 Sulfatases signature 1 (atsB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3294Rv3300chypothetical protein Rv3300c {Mycobacterium tuberculosis H37Rv (lab strain)}
3295Rv3301c, (MTCI418A.03c), len: 221 aa phoY, probablephosphate transport system regulatory protein, highly similar to M. leprae Q50047 phoY (222 aa), fasta scores; opt:929 z-score: 1110.0 E(): 0, 61.5% identity in 218 aa overlap.Also similar to MTV043_13 (213 aa, (phoY1) {Mycobacterium tuberculosis H37Rv (lab strain)}
3296Rv3302c, (MTCI418A.04c-MTV016.01c), len: 585, glpd2, glycerol-3-phosphate dehydrogenase, almost identical M. leprae GLPD_MYCLE P53435 glycerol-3-phosphate dehydrogenase (585 aa, 90.8% identity in 584 aa overlap), fasta scores; opt: 2318 z-score: 2657.7 E(): 0, 9 (glpD2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3297Rv3303c, (MTV016.02c), len: 493. Probable dihydrolipoamide dehydrogenase similar to many e.g. Q04829|DLDH_HALVO (474 aa) from HALOFERAX VOLCANII. FASTA scores: sp|Q04829|DLDH_HALVO DIHYDROLIPOAMIDE DEHYDROGENASE (E (474 aa) opt:675 z-score: 794.6 E(): 0; 29.3% i (lpdA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3298Rv3304hypothetical protein Rv3304 {Mycobacterium tuberculosis H37Rv (lab strain)}
3299Rv3305c, (MTV016.04c), len: 389. amiA, Probable N-acyl-L-amino acid amidohydrolase or peptidase similar to many e.g. Bacillus subtilis BSUB0015_194 (416 aa) and P54984|Y100_SYNY3 (393 aa). Contains PS00639 Eukaryotic thiol (cysteine) proteases histidine active s (amiA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3300Rv3306c, (MTV016.05c), len: 394. amiB, Probable aminohydrolase similar to several belonging to peptidase family M40 (and to hypothetical proteins) e.g. AMHX_BACSU (383 aa). FASTA scores: sptr|P76052|P76052 (481 aa) opt: 383 z-score: 455.1 E(): 7.3e-18; 30.5% ide (amiB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3301Rv3307, (MTV016.06), len: 268, deoD, probable purine nucleoside phosphorylase similar to several especially M.leprae DEOD_MYCLE (268 aa) and DEOD_BACST (274 aa). FASTA scores: sp|P46862|DEOD_MYCLE PROBABLE PURINE NUCLEOSIDE PHOSPH (268 aa) opt: 1373 z-score: 16 (deoD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3302Rv3308, (MTV016.07), len: 534. Probable phosphomannomutase similar to several e.g. Mycobacterium leprae L308_F1_13 (534 aa) and sp|P18159|YHXB_BACSU (565 aa). Contains PS00710 Phosphoglucomutase and phosphomannomutase phosphoserine signature. FASTA scores: U000 (pmmB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3303Rv3309c, (MTV016.08c), len: 207, upp, Uracil phosphoribosyltransferase, identical to Mycobacterium bovis uracil phosphoribosyltransferase. FASTA scores: U77913|MBU77913_1 Mycobacterium bovis uracil phosph (207 aa) opt: 1346 z-score: 1618.6 E(): 0; 99.5% identity (upp) {Mycobacterium tuberculosis H37Rv (lab strain)}
3304Rv3310hypothetical protein Rv3310 {Mycobacterium tuberculosis H37Rv (lab strain)}
3305Rv3311hypothetical protein Rv3311 {Mycobacterium tuberculosis H37Rv (lab strain)}
3306Rv3312chypothetical protein Rv3312c {Mycobacterium tuberculosis H37Rv (lab strain)}
3307Rv3313c, (MTV016.13), len: 365, add, probable adenosine deaminase (EC 3.5.4.4) similar to several e.g. P22333|ADD_ECOLI (333 aa) and especially to Mycobacterium leprae cosmid L308_C2_206 (332). FASTA scores: U00022_14 Mycobacterium leprae cosmid L308. (332 aa) o (add) {Mycobacterium tuberculosis H37Rv (lab strain)}
3308Rv3314c, (MTV016.14), len: 427. deoA, probable thymidine phosporylase, similar to many e.g. P77836|PDP_BACST (433 aa) best with human TYPH_HUMAN (482 aa). Contains PS00647 Thymidine and pyrimidine-nucleoside phosphorylases signature. FASTA scores: sp|P19971|TYPH (deoA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3309Rv3315c, (MTV016.15c), len: 133. cdd, probable cytidine deaminase similar to several best with Brugia malayi enzyme P90706 (133 aa). Contains PS00903 Cytidine and deoxycytidylate deaminases zinc-binding region signature. FASTA scores: sptr|P90706|P90706 CYTIDINE (cdd) {Mycobacterium tuberculosis H37Rv (lab strain)}
3310Rv3316, (MTV016.16), len: 112. sdhC, probable SdhC subunit, membrane anchor of succinate dehydrogenase (EC 1.3.99.1). Similar to several e.g. Natronobacterium pharaonis Y07709|NPSDHCDBA_2 (130 aa) but closest to C-terminal half of M. leprae protein Q49919 L308_ (sdhC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3311Rv3317, (MTV016.17), len: 144, sdhD, Probable SdhD subunit, membrane anchor of succinate dehydrogenase (EC 1.3.99.1). Similar to several e.g. P41086|DHSD_RICPR (125 aa),closest to M. leprae Q49915 L308_F1_25 (163 aa). FASTA scores: sptr|Q49915|Q49915 L308_F1_25 (sdhD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3312Rv3318, (MTV016.18), len: 590. sdhA, probable flavoprotein subunit of succinate dehydrogenase (EC 1.3.99.1). Similar to many, e.g.g DHSA_ECOLI (588 aa) closest to M. leprae L308_F3_120 (401 aa). Contains PS00504 Fumarate reductase / succinate dehydrogenase FAD- (sdhA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3313Rv3319, (MTV016.19), len: 263. sdhB, iron-sulphur protien subunit of succinate dehydrogenase (EC 1.3.99.1). Similar to many e.g. P07014|DHSB_ECOLI (238 aa) closest to M.leprae Q49916 L308_F1_28 (264 aa). Contains PS00198 4Fe-4Sferredoxins, iron-sulfur binding r (sdhB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3314Rv3320chypothetical protein Rv3320c {Mycobacterium tuberculosis H37Rv (lab strain)}
3315Rv3321chypothetical protein Rv3321c {Mycobacterium tuberculosis H37Rv (lab strain)}
3316Rv3322c, (MTV016.22c), len: 204. Unknown, similar to Mycobacterium tuberculosis protein MTCY164.30 (200 aa), FASTA scores: gp|Z95150|MTCY164_31 (200 aa) opt: 691 z-score: 871.8 E(): 0; 57.0% identity in 200 aa overlap. Also similat to D90917_85 Synechocystis sp (moaE3) {Mycobacterium tuberculosis H37Rv (lab strain)}
3317Rv3323c, (MTV016.23c), len: 221. gphA, Probable MoaD-MoaE fusion protein involved in molybdopterin synthesis, similar to several MoaD and MoaE proteins especially Mycobacterium tuberculosis MoaE; MTCY164.29 (147 aa) and MTCY164.22 (83 aa). FASTA scores: Z95150|M (gphA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3318Rv3324c, (MTV016.24c), len: 177. MoaC2, probably involved in molybdopterin synthesis similar to many MoaC proteins especially MTCY164.21 (170 aa). FASTA scores: Z95150|MTCY164_22 (170 aa) opt: 734 z-score: 946.1 E(): 0; 71.8% identity in 163 aa overlap. TBparses (moaC3) {Mycobacterium tuberculosis H37Rv (lab strain)}
3319Rv3325hypothetical protein Rv3325 {Mycobacterium tuberculosis H37Rv (lab strain)}
3320Rv3326hypothetical protein Rv3326 {Mycobacterium tuberculosis H37Rv (lab strain)}
3321Rv3327hypothetical protein Rv3327 {Mycobacterium tuberculosis H37Rv (lab strain)}
3322Rv3328c, (MTV016.28c, sigJ), len: 312. Probable sigma factor, similar to several closest to Mycobacterium tuberculosis MTV005.25 (249 aa, partial seq.). FASTA scores: AL0101|MTV005_25 (249 aa) opt: 426 z-score: 511.5 E(): 5.3e-21; 35.9% identity in 223 aa overl (sigJ) {Mycobacterium tuberculosis H37Rv (lab strain)}
3323Rv3329hypothetical protein Rv3329 {Mycobacterium tuberculosis H37Rv (lab strain)}
3324Rv3330hypothetical protein Rv3330 {Mycobacterium tuberculosis H37Rv (lab strain)}
3325Rv3331, (MTV016.31), len: 502. Probable sygar transport protein, similar to several e.g. P37021|GALP_ECOLI (464 aa). Contains PS00216 Sugar transport proteins signature 1 and PS00217 Sugar transport proteins signature 2. Start uncertain. FASTA scores: sp|P37021 (sugI) {Mycobacterium tuberculosis H37Rv (lab strain)}
3326Rv3332, (MTV016.32), len: 383. nagA, probable N-acetylglucosamine-6-phosphate deacetylase similar to several e.g. BSUB0018_187 (396 aa). FASTA scores: Z99121|BSUB0018_187 Bacillus subtilis (396 aa) opt: 571 z-score: 643.5 E(): 2.4e-28; 32.4% identity in 376 aa (nagA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3327Rv3333chypothetical protein Rv3333c {Mycobacterium tuberculosis H37Rv (lab strain)}
3328Rv3334hypothetical protein Rv3334 {Mycobacterium tuberculosis H37Rv (lab strain)}
3329Rv3335chypothetical protein Rv3335c {Mycobacterium tuberculosis H37Rv (lab strain)}
3330Rv3336c, (MTV016.36c), len: 336, trpS, probable tryptophanyl tRNA synthetase similar to many, closest to M. leprae enzyme. Contains PS00178 Aminoacyl-transfer RNA synthetases class-I signature. FASTA scores: sp|Q49901|SYW_MYCLE TRYPTOPHANYL-TRNA SYNTHETASE (343 (trpS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3331Rv3337hypothetical protein Rv3337 {Mycobacterium tuberculosis H37Rv (lab strain)}
3332Rv3338hypothetical protein Rv3338 {Mycobacterium tuberculosis H37Rv (lab strain)}
3333Rv3339c, (MTV016.39c), len: 409, icd, probable isocitrate dehydrogenase similar to many. Contains PS00470 Isocitrate and isopropylmalate dehydrogenases signature. FASTA scores: sp|P50215|IDH_SPHYA ISOCITRATE DEHYDROGENASE (NADP)(E (406 aa) opt: 1964 z-score: 235 (icd1) {Mycobacterium tuberculosis H37Rv (lab strain)}
3334Rv3340, (MTV016.40), len: 449. Probable homocysteine synthase (EC 4.2.99.10) similar to many fungal enzymes e.g. P50125|CYSD_EMENI (437 aa). Contains PS00868 Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. FASTA scores: sp|P50125|CYSD_EMENI O-AC (metC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3335Rv3341, (MTV016.41), len: 379. Probable homoserine o-acetyltransferase similar to many but closest to M. leprae enzyme MLCB1779_3 O32874 (382 aa). FASTA scores: gp|Z98271|MLCB1779_3 Mycobacterium leprae cosmid B1779 (382 aa) opt: 2263 z-score: 2524.2 E(): 0; 85 (metA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3336Rv3342hypothetical protein Rv3342 {Mycobacterium tuberculosis H37Rv (lab strain)}
3337Rv3343c, (MTV016.43c), len: 2523. Member of PPE-family of M. tuberculosis proteins, Gly-, Asn-rich MPTR subgroup. Most similar to MTV004_5 (3716 aa). FASTA scores: gp|AL0091|MTV004_5 Mycobacterium tuberculosis sequence (3716 aa)opt: 4672 z-score: 3736.8 E(): 0; (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3338Rv3344cProtein sequence is in conflict with the conceptual translation; Rv3344c, (MTV016.44c), len: 484. Member of the M. tuberculosis PE-PGRS group of Gly, Ala-rich proteins. Appears to be a gene fragment, should be in-frame with following orf, MTV016.45c, fram (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3339Rv3345c, (MTV004.01c-MTV016.45c), member of the M. tuberculosis PE-PGRS family of Glycine-rich proteins, len 1538; similar to many eg. Y0DP_MYCTU Q50615 MTCY1A11.25Cc(498 aa), fasta scores; opt: 1646 z-score: 657.9 E(): 1.7e-29,55.0% identity in 565 aa overlap. (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3340Rv3346chypothetical protein Rv3346c {Mycobacterium tuberculosis H37Rv (lab strain)}
3341Rv3347c, (MTV004.03c), member of the M. tuberculosis PPE family of Gly-, Ala-, Asn-rich proteins), len: 3157 aa; similar to many eg. TR:O07232 (EMBL:Z96800) MTCY63.10c (963 aa), opt: 1181 z-score: 2191.5 E(): 0, 47.5% identity in 995 aa overlap. Also similar to (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3342Rv3348hypothetical protein Rv3348 {Mycobacterium tuberculosis H37Rv (lab strain)}
3343Rv3349chypothetical protein Rv3349c {Mycobacterium tuberculosis H37Rv (lab strain)}
3344Rv3350c, (MTV004.07c), len: 3716, member of the M. tuberculosis PPE family of Gly-, Ala-, Asn-rich proteins, similar to many eg. Y04H_MYCTU Q10778 MTCY48.17 (734 aa), fasta scores; opt: 1264 z-score: 1136.3 E(): 0, 47.4% identity in 546 aa overlap. Also similar (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3345Rv3351chypothetical protein Rv3351c {Mycobacterium tuberculosis H37Rv (lab strain)}
3346Rv3352chypothetical protein Rv3352c {Mycobacterium tuberculosis H37Rv (lab strain)}
3347Rv3353chypothetical protein Rv3353c {Mycobacterium tuberculosis H37Rv (lab strain)}
3348Rv3354hypothetical protein Rv3354 {Mycobacterium tuberculosis H37Rv (lab strain)}
3349Rv3355chypothetical protein Rv3355c {Mycobacterium tuberculosis H37Rv (lab strain)}
3350Rv3356c, (MTV004.13c), len: 281, folD, methylenetetrahydrofolate dehydrogenase, similar to many eg. FOLD_ECOLIP24186 methylenetetrahydrofolate dehydrogenase (EC 1.5.1.5)(287 aa), fasta scores; 741 z-score: 853.3 E(): 0, 44.4% identity in 277 aa overlap. Also hig (folD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3351Rv3357hypothetical protein Rv3357 {Mycobacterium tuberculosis H37Rv (lab strain)}
3352Rv3358hypothetical protein Rv3358 {Mycobacterium tuberculosis H37Rv (lab strain)}
3353Rv3359hypothetical protein Rv3359 {Mycobacterium tuberculosis H37Rv (lab strain)}
3354Rv3360hypothetical protein Rv3360 {Mycobacterium tuberculosis H37Rv (lab strain)}
3355Rv3361chypothetical protein Rv3361c {Mycobacterium tuberculosis H37Rv (lab strain)}
3356Rv3362chypothetical protein Rv3362c {Mycobacterium tuberculosis H37Rv (lab strain)}
3357Rv3363chypothetical protein Rv3363c {Mycobacterium tuberculosis H37Rv (lab strain)}
3358Rv3364chypothetical protein Rv3364c {Mycobacterium tuberculosis H37Rv (lab strain)}
3359Rv3365chypothetical protein Rv3365c {Mycobacterium tuberculosis H37Rv (lab strain)}
3360Rv3366, (MTV004.23), len: 154; probable rRNA methylase similar to many members of the spoU family of rRNA methylases eg. YIBK_ECOLI P33899 (157 aa), fasta scores; opt: 511 z-score: 924.9 E(): 0, 49.4% identity in 154 aa overlap (spoU) {Mycobacterium tuberculosis H37Rv (lab strain)}
3361Rv3367, (MTV004.25), member of the M. tuberculosis PE-PGRS family of Gly-rich proteins; len: 588 aa; similar to many eg. YW36_MYCTU Q10873 MTCY39.36c (558 aa), fasta scores; opt: 990 z-score: 664.7 E(): 7.2e-30, 51.0% identity in 351 aa overlap. Also similar to (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3362Rv3368chypothetical protein Rv3368c {Mycobacterium tuberculosis H37Rv (lab strain)}
3363Rv3369hypothetical protein Rv3369 {Mycobacterium tuberculosis H37Rv (lab strain)}
3364Rv3370c, (MTV004.28c), len: 1079, dnaE, probable DNA polymerase III alpha chain), similar to many eg. DP3A_VIBCH P52022 dna polymerase iii, alpha chain (ec 2.7.7.7) (1159 aa), fasta scores; opt: 702 z-score: 1055.9 E(): 0, 30.8%identity in 1068 aa overlap. Also (dnaE2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3365Rv3371hypothetical protein Rv3371 {Mycobacterium tuberculosis H37Rv (lab strain)}
3366Rv3372, (MTV004.30),len: 391, possible trehalose-6-phosphate phosphatase, similar to M. leprae TR:Q49734 MLCL383.17C (EMBL:Z97179) (429 aa), fasta scores; opt: 1675 z-score: 2127.4 E(): 0, 67.1% identity in 425 aa overlap, and weakly similar to several trehalos (otsB2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3367Rv3373, (MTV004.31), len: 213, echA18, probable enoyl-coA hydratase (crotonase), similar to several eg. TR:P97087 (EMBL:Z92974) CROTONASE (EC 4.2.1.17) (ENOYL-COA HYDRATASE) (259 aa), fasta scores; opt: 423 z-score: 608.8 E(): 9.4e-27, 37.9% identity in 174 aa (echA18) {Mycobacterium tuberculosis H37Rv (lab strain)}
3368Rv3374, (MTV004.32), len: 82, echA18, possible enoyl-coA hydratase C-terminus, similar to the C-terminus ofTR:P97087 (EMBL:Z92974) CROTONASE (EC 4.2.1.17) (ENOYL-COAHYDRATASE) (259 aa), fasta scores; opt: 115 z-score: 171.1E(): 0.023, 32.9% identity in 82 aa ov (echA18) {Mycobacterium tuberculosis H37Rv (lab strain)}
3369Rv3375, (MTV004.33), len: 475, amiD, probable amidase similar to many eg. TR:Q53116 (EMBL:M74531) ENANTIOMERASE-SELECTIVE AMIDASE from RHODOCOCCUS sp. (462 aa), fasta scores; opt: 1036 z-score: 990.5 E(): 0, 38.6% identity in 464 aa overlap. Also similar to M. (amiD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3370Rv3376hypothetical protein Rv3376 {Mycobacterium tuberculosis H37Rv (lab strain)}
3371Rv3377chypothetical protein Rv3377c {Mycobacterium tuberculosis H37Rv (lab strain)}
3372Rv3378chypothetical protein Rv3378c {Mycobacterium tuberculosis H37Rv (lab strain)}
3373Rv3379chypothetical protein Rv3379c {Mycobacterium tuberculosis H37Rv (lab strain)}
3374Rv3380chypothetical protein Rv3380c {Mycobacterium tuberculosis H37Rv (lab strain)}
3375Rv3381chypothetical protein Rv3381c {Mycobacterium tuberculosis H37Rv (lab strain)}
3376Rv3382c, (MTV004.40c), len: 329, lytB protein homolog, highly similar to many eg. LYTB_ECOLI P22565 lytb protein (316 aa), fasta scores; opt: 1013 z-score: 1058.5 E(): 0, 51.4% identity in 311 aa overlap (lytB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3377Rv3383c, (MTV004.41c), len: 350, probable transferase similar to many transferases involved in lipid biosynthesis eg. GGPP_MYCTU Q50727 probable geranylgeranyl pyrophosphate synthetase (359 aa), fasta scores; opt: 687 z-score: 853.4 E(): 0, 39.1% identity in 325 (idsB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3378Rv3384chypothetical protein Rv3384c {Mycobacterium tuberculosis H37Rv (lab strain)}
3379Rv3385chypothetical protein Rv3385c {Mycobacterium tuberculosis H37Rv (lab strain)}
3380Rv3386hypothetical protein Rv3386 {Mycobacterium tuberculosis H37Rv (lab strain)}
3381Rv3387hypothetical protein Rv3387 {Mycobacterium tuberculosis H37Rv (lab strain)}
3382Rv3388, (MTV004.46, member of the M. tuberculosis PE_PGRS family of Gly-rich proteins), len: 731 aa; similar to many eg. Y0BA_MYCTU Q50630 MTCY227.10C (543 aa), fasta scores; opt: 1725 z-score: 730.9 E(): 0, 52.3% identity in 610 aa overlap, also similar to MTV (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3383Rv3389chypothetical protein Rv3389c {Mycobacterium tuberculosis H37Rv (lab strain)}
3384Rv3390, (MTV004.48), len: 236, unknown, some similarity to M. tuberculosis hypothetical protein TR:O06391 (EMBL:Z95558) MTCY25D10.04 (202 aa), fasta scores; opt: 178 z-score: 277.3 E(): 2.8e-08, 27.3% identity in 165 aa overlap.Contains signal sequence and appr (lpqD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3385Rv3391, (MTV004.49), len: 650, acrA1, fatty acyl-CoA reductase, identical to, but longer than, M. tuberculosisTR:Q11197 (EMBL:U27357) HYPOTHETICAL 41.9 KD PROTEIN IN CMA1 3REGION (384 aa), due to use of a more upstream start site. Multi-domain enzyme, N-terminu (acrA1) {Mycobacterium tuberculosis H37Rv (lab strain)}
3386Rv3392c, (MTV004.50), len: 287, cmaA1, cyclopropanemycolic acid synthase, identical to CFA1_MYCTU Q11195 cyclopropane-fatty-acyl-phospholipid synthase 1. See Yuan et al.Proc Natl Acad Sci U.S.A. (1995) 92(14):6630-6634. Also highly similar to M. tuberculosis gen (cmaA1) {Mycobacterium tuberculosis H37Rv (lab strain)}
3387Rv3393, (MTV004.51), len: 308, probable nucleoside hydrolase, similar to IUNH_CRIFA Q27546 inosine-uridine preferring nucleoside hydrolase from Crithidia fasciculata (314 aa), fasta scores; opt: 475 z-score: 591.6 E(): 8.6e-26, 31.2% identity in 317 aa overlap; (iunH) {Mycobacterium tuberculosis H37Rv (lab strain)}
3388Rv3394chypothetical protein Rv3394c {Mycobacterium tuberculosis H37Rv (lab strain)}
3389Rv3395chypothetical protein Rv3395c {Mycobacterium tuberculosis H37Rv (lab strain)}
3390Rv3396c, (MTCY78.32), len: 525, guaA, gmp synthase, highly similar to Mycobacterium leprae U00015_15 GUAA_MYCLE P46810 gmp synthase (glutamine-hydrolyzing) (590 aa) Fasta scores, opt: 3000, z-score: 3351.4, E(): 0, (86.3% identity in 531 aa overlap); contains PS (guaA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3391Rv3397c, (MTCY78.31), len: 302, phytoene synthase, similar to many, e.g. PSY2_LYCES P37273 phytoene synthase 2precursor (310 aa) Fasta scores, opt: 421, z-score: 500.0,E(): 6.6e-21, (32.9% identity in 295 aa overlap); containsPS01045 Squalene and phytoene syntha (phyA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3392Rv3398c, (MTCY78.30), len: 359, GGPP synthetase, most similar to AE000797_3 Methanobacterium thermoautotrop O26156 bifunctional short chain isoprenyl diphosphate synthase (325 aa) FASTA scores, opt: 605, z-score: 738.4, E(): 0,(37.1% identity in 329 aa overlap); (idsA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3393Rv3399hypothetical protein Rv3399 {Mycobacterium tuberculosis H37Rv (lab strain)}
3394Rv3400hypothetical protein Rv3400 {Mycobacterium tuberculosis H37Rv (lab strain)}
3395Rv3401hypothetical protein Rv3401 {Mycobacterium tuberculosis H37Rv (lab strain)}
3396Rv3402chypothetical protein Rv3402c {Mycobacterium tuberculosis H37Rv (lab strain)}
3397Rv3403chypothetical protein Rv3403c {Mycobacterium tuberculosis H37Rv (lab strain)}
3398Rv3404chypothetical protein Rv3404c {Mycobacterium tuberculosis H37Rv (lab strain)}
3399Rv3405chypothetical protein Rv3405c {Mycobacterium tuberculosis H37Rv (lab strain)}
3400Rv3406hypothetical protein Rv3406 {Mycobacterium tuberculosis H37Rv (lab strain)}
3401Rv3407hypothetical protein Rv3407 {Mycobacterium tuberculosis H37Rv (lab strain)}
3402Rv3408hypothetical protein Rv3408 {Mycobacterium tuberculosis H37Rv (lab strain)}
3403Rv3409c, (MTCY78.19), len: 578, choD, highly similar to U00015_19 M. leprae G466945Q59530 PROBABLE CHOLESTEROL OXIDASE PRECURSOR CHOD (585 aa) fasta scores, opt: 3544,z-score: 3844.6, E(): 0, (88.4% identity in 576 aa overlap); contains PS00017 ATP/GTP-binding s (choD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3404Rv3410c, (MTCY78.18), len: 375, guaB3, but similar to D90910_39 Synechocystis P73853 IMP DEHYDROGENASE SUBUNIT(387 aa, E(): 0, 41.3% identity in 373 aa overlap). Highlysimilar to U00015_20, M. leprae Y09J_MYCLE (375 aa) fasta scores, opt: 2182, z-score: 2448.1, (guaB3) {Mycobacterium tuberculosis H37Rv (lab strain)}
3405Rv3411c, (MTCY78.17), len: 529, guaB2, inosine-5-monophosphate dehydrogenase, highly similar to Q49729|IMDH_MYCLE INOSINE-5-MONOPHOSPHATE DEHYDROGENASE (529 aa), FASTAscores, opt: 3154 z-score: 3270.6 E(): 0, (92.4% identity in 529 aa overlap), similar to IMDH_A (guaB2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3406Rv3412hypothetical protein Rv3412 {Mycobacterium tuberculosis H37Rv (lab strain)}
3407Rv3413chypothetical protein Rv3413c {Mycobacterium tuberculosis H37Rv (lab strain)}
3408Rv3414c, (MTCY78.15), len: 212, sigD, similar to CNRH_ALCEU P37978 rna polymerase sigma factor cnrh (191 aa), fasta scores, opt: 197, z-score: 246.1, E(): 9.1e-07, (30.4% identity in 191 aa overlap) also highly similar to part G466942 S1620B (59 aa) Fasta scores (sigD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3409Rv3415chypothetical protein Rv3415c {Mycobacterium tuberculosis H37Rv (lab strain)}
3410Rv3416, (MTCY78.13c), len: 102, whiB, regulatory protein, highly similar to U00020_2 Mycobacterium leprae cosmid B229 and M. leprae U00015_26 cosmid B1620(102 aa) opt: 657, z-score: 807.1, E(): 0, (86.3% identity in 102 aa overlap) (whiB3) {Mycobacterium tuberculosis H37Rv (lab strain)}
3411Rv3417c, (MTCY78.12, cpn60-1 gene), len: 539,groEL1, 60 kd chaperonin 1 (protein cpn60 1) identical to X60350|MTGROEOP_2 M;tuberculosis groE (G44601); contains PS00017 ATP/GTP-binding site motif A, PS00296 Chaperonins cpn60 signature. Also highly similar to U000 (groEL1) {Mycobacterium tuberculosis H37Rv (lab strain)}
3412Rv3418c, (MTCY78.11), len: 100, groES, identical toCH10_MYCTU P09621 10 kd chaperonin (protein cpn10); also identical to MSG10KAG_1, MT10KAG_1, MTBCGA_1 contains PS00681Chaperonins cpn10 signature (groES) {Mycobacterium tuberculosis H37Rv (lab strain)}
3413Rv3419c, (MTCY78.10), len: 344, gcp, Glycoprotease highly similar to M. leprae U1620C, Q49725, G466938, (351 aa) opt: 1898, z-score: 2029.2, E(): 0, (86.1% identity in 345 aa overlap), also similar eg to GCP_HAEIN P43764 probable o-sialoglycoprotein endopeptidas (gcp) {Mycobacterium tuberculosis H37Rv (lab strain)}
3414Rv3420c, (MTCY78.09), len: 158 rimI, acetyltransferase, highly similar to U00020_6 (G467109) M. leprae cosmid B229 (359 aa) fasta scores, opt: 772, z-score: 888.2, E(): 0, (72.1% identity in 154 aa overlap) and similar to RIMI_ECOLI P09453 ribosomal-protein-alan (rimI) {Mycobacterium tuberculosis H37Rv (lab strain)}
3415Rv3421chypothetical protein Rv3421c {Mycobacterium tuberculosis H37Rv (lab strain)}
3416Rv3422chypothetical protein Rv3422c {Mycobacterium tuberculosis H37Rv (lab strain)}
3417Rv3423c, (MTCY78.06), len: 408, alr, alanine racemase, highly similar to U00020_9 Mycobacterium leprae ALR_MYCLE P38056 alanine racemase (388 aa) FASTA scores, opt: 2160, z-score: 2453.0, E(): 0, (84.4% identity in 384 aa overlap) and other ALANINE RACEMASES (alr) {Mycobacterium tuberculosis H37Rv (lab strain)}
3418Rv3424chypothetical protein Rv3424c {Mycobacterium tuberculosis H37Rv (lab strain)}
3419Rv3425, (MTCY78.04c), len: 176, unknown, some similarity to PPE_family members. Most similar to downstream Rv3429 (MTCY77_1), MTCY78_3, MTV049_11, MTCY428_16, MTV049_22,MTV049_30, MTCY261_4 etc. fasta scores: YHS6_MYCTU P42611hypothetical 50.6 kd protein in hsp (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3420Rv3426, (MTCY78.03c), len: 232, unknown, similar toPPE_family, e.g. YHS6_MYCTU P42611 hypothetical 50.6 kd protein in hsp65 (517 aa) fasta scores, opt: 197, z-score:217.5, E(): 3.6e-05, (29.6% identity in 152 aa overlap), alsosimilar to upstream Rv3425 MTCY78.0 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3421Rv3427chypothetical protein Rv3427c {Mycobacterium tuberculosis H37Rv (lab strain)}
3422Rv3428chypothetical protein Rv3428c {Mycobacterium tuberculosis H37Rv (lab strain)}
3423Rv3429, (MTCY77.01), len: 178 aa. member of PPE family, similar to upstream M. tuberculosis Y094_MYCTU Q50703,hypothetical 19.9 kd protein cy78.04c (176 aa), fasta scores, opt: 781, E(): 0, (69.9% identity in 176 aa overlap), also Y093_MYCTU Q50702 hypothetical (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3424Rv3430chypothetical protein Rv3430c {Mycobacterium tuberculosis H37Rv (lab strain)}
3425Rv3431chypothetical protein Rv3431c {Mycobacterium tuberculosis H37Rv (lab strain)}
3426Rv3432c, (MTCY77.04c), len: 460 aa. gadB, Probable glutamate decarboxylase, similar to eg DCE_PETHY Q07346 glutamate decarboxylase (4.1.1.15) (500 aa), fasta scores, opt: 1485, E(): 0, (50.3% identity in 437 aa overlap) (gadB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3427Rv3433chypothetical protein Rv3433c {Mycobacterium tuberculosis H37Rv (lab strain)}
3428Rv3434chypothetical protein Rv3434c {Mycobacterium tuberculosis H37Rv (lab strain)}
3429Rv3435chypothetical protein Rv3435c {Mycobacterium tuberculosis H37Rv (lab strain)}
3430Rv3436c, (MTCY77.08c), len: 624 aa. glmS, probableglucosamine-fructose-6-phosphate aminotransferasehighly similar to M. leprae GLMS_MYCLE P40831 probable glucosamine--fructose-6-phosphate aminotransferase (624 aa), fasta scores, opt: 3570, E(): 0, (89.0% identit (glmS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3431Rv3437hypothetical protein Rv3437 {Mycobacterium tuberculosis H37Rv (lab strain)}
3432Rv3438hypothetical protein Rv3438 {Mycobacterium tuberculosis H37Rv (lab strain)}
3433Rv3439chypothetical protein Rv3439c {Mycobacterium tuberculosis H37Rv (lab strain)}
3434Rv3440chypothetical protein Rv3440c {Mycobacterium tuberculosis H37Rv (lab strain)}
3435Rv3441c, (MTCY77.13c), len: 448 aa. Probable phosphoglucomutase or phosphomannomutasehighly similar to M. leprae Q49869 URED (463 aa) fasta scores, opt: 2449, E(): 0, (87.6% identity in 445 aa overlap) and Q49862 UREC, (288 aa), fasta scores, opt: 1442, E(): 0, (mrsA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3436Rv3442c, (MTCY77.14c), len: 151. rpsI. Ribosomal protein S9 ighly similar to RS9_MYCLE P40828 30s ribosomal protein s9 (153 aa), fasta scores, opt: 800, E(): 0, (83.9% identity in 155 aa overlap); contains PS00360 Ribosomal protein S9 signature (rpsI) {Mycobacterium tuberculosis H37Rv (lab strain)}
3437Rv3443c, (MTCY77.15c), len: 147 aa. rplM, 50S ribosomal protein L13, highly similar to RL13_MYCLE P38014 50s ribosomal protein l13 (147 aa), fasta scores, opt: 917, E():0, (91.2% identity in 147 aa overlap) (rplM) {Mycobacterium tuberculosis H37Rv (lab strain)}
3438Rv3444chypothetical protein Rv3444c {Mycobacterium tuberculosis H37Rv (lab strain)}
3439Rv3445chypothetical protein Rv3445c {Mycobacterium tuberculosis H37Rv (lab strain)}
3440Rv3446chypothetical protein Rv3446c {Mycobacterium tuberculosis H37Rv (lab strain)}
3441Rv3447chypothetical protein Rv3447c {Mycobacterium tuberculosis H37Rv (lab strain)}
3442Rv3448hypothetical protein Rv3448 {Mycobacterium tuberculosis H37Rv (lab strain)}
3443Rv3449hypothetical protein Rv3449 {Mycobacterium tuberculosis H37Rv (lab strain)}
3444Rv3450chypothetical protein Rv3450c {Mycobacterium tuberculosis H37Rv (lab strain)}
3445Rv3451hypothetical protein Rv3451 {Mycobacterium tuberculosis H37Rv (lab strain)}
3446Rv3452hypothetical protein Rv3452 {Mycobacterium tuberculosis H37Rv (lab strain)}
3447Rv3453hypothetical protein Rv3453 {Mycobacterium tuberculosis H37Rv (lab strain)}
3448Rv3454hypothetical protein Rv3454 {Mycobacterium tuberculosis H37Rv (lab strain)}
3449Rv3455c, (MTCY13E12.08c), len: 256. Function: possible pseudouridylate synthase, some similarity to pseudouridylate synthase. FASTA results: TRUA_ECOLI P07649 pseudouridylate synthase (270 aa) opt: 315; E(): 1.6e-14; (33.3% identity in 240 aa overlap) (truA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3450Rv3456c, (MTCY13E12.09c), len: 180. rplQ. Function:probable 50S ribosomal protein L17. FASTA results: RL17_ECOLI P02416 50s ribosomal protein l17 (127 aa) opt: 347; E():5e-13; (50.4% identity in 119 aa overlap) (rplQ) {Mycobacterium tuberculosis H37Rv (lab strain)}
3451Rv3457c, (MTCY13E12.10c), len: 347. rpoA. Function:probable alpha subunit of RNA polymerase. Contains ATP/GTP-binding site motif A (P-loop; PS00017). FASTA results: RPOA_STRCO P72404 dna-directed rna polymerase alpha chain (339aa) opt: 1644; E(): 0; (75.0% ident (rpoA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3452Rv3458c, (MTCY13E12.11c), len: 201. rpsD. Function:probable ribosomal protein S4. Contains ribosomal protein S4 signature (PS00632) and ATP/GTP binding site motif (PS00017). FASTA results: identical to RS4_MYCBO P45811 30s ribosomal protein s4 (fragment) (131 aa (rpsD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3453Rv3459c, (MTCY13E12.12c), len: 139. rpsK. Function:probable ribosomal protein S11, contains ribosomal proteinS11 signature (PS00054). FASTA results: RS11_MYCBO P45812 30s ribosomal protein s11 (139 aa) opt: 867; E(): 0; (94.2%identity in 139 aa overlap) (rpsK) {Mycobacterium tuberculosis H37Rv (lab strain)}
3454Rv3460c, (MTCY13E12.13c), len: 124. rpsM. Function:probable ribosomal protein S13, contains ribosomal proteinS13 signature (PS00646). FASTA results: RS13_MYCBO P45813 (123 aa) opt: 727; E(); (98.2% identity in 114 aa overlap) (rpsM) {Mycobacterium tuberculosis H37Rv (lab strain)}
3455Rv3461c, (MTCY13E12.14c), len: 37. rpmJ. Probable ribosomal protein L36. identical to P45810|RL36_MYCBO 50S RIBOSOMAL PROTEIN L36 (37 aa), contains PS00828 Ribosomal protein L36 signature (rpmJ) {Mycobacterium tuberculosis H37Rv (lab strain)}
3456Rv3462c, (MTCY13E12.15c), len: 73 aa. infA. Probable initiation factor IF-1. FASTA results: identical to IF1_MYCBO P45957 initiation factor if-1 (72 aa) (infA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3457Rv3463hypothetical protein Rv3463 {Mycobacterium tuberculosis H37Rv (lab strain)}
3458Rv3464, (MTCY13E12.17), len: 331. rmlB. Function: probable DTDP-GLUCOSE 4,6-DEHYDRATASE nearly identical to Mycobacterium tuberculosis rhamnose biosynthesis protein (previously rfbB, now known as rmlB) gene. FASTA results: Q50556 RHAMNOSE BIOSYNTHESIS PROTEIN ( (rmlB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3459Rv3465, (MTCY13E12.18), len: 202. rmlC. Probable dtdp-4-dehydrorhamnose 3,5-epimerase. Nearly identical to M. tuberculosis sp|O33170|O33170 RMLC PROTEIN (203 aa) opt: 1171 z-score: 1465.1 E(): 0; 89.5% identity in 200 aa overlap. Previously known as rfbC. FASTA (rmlC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3460Rv3466hypothetical protein Rv3466 {Mycobacterium tuberculosis H37Rv (lab strain)}
3461Rv3467hypothetical protein Rv3467 {Mycobacterium tuberculosis H37Rv (lab strain)}
3462Rv3468c, (MTCY13E12.21c), len: 364. Function: similar to many dtdp-glucose 4,6-dehydratases (EC 4.2.1.46). First start taken, alternative at 17080 in cSCYY13E12 suggested by similarity. FASTA results: Q39077 HOMOLOG OF DTDP-GLUCOSE 4-6-DEHYDRATASES. (445 aa) opt (rmlB3) {Mycobacterium tuberculosis H37Rv (lab strain)}
3463Rv3469c, (MTCY13E12.22c), len: 336. mhpE: probable 4-hydroxy-2-oxovalerate aldolase. FASTA results: BPHF_PSES1P51014 4-hydroxy-2-oxovalerate aldolase (EC 4.1.3.-) (352 aa) opt: 549; E(): 1e-28; (31.2% identity in 314 aa overlap). Similar to MTCY03C7.22 (FASTA sc (mhpE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3464Rv3470c, (MTCY13E12.23c), len: 552. ilvB: probable acetolactate synthase large subunit (EC 4.1.3.18). Containsthiamine pyrophosphate enzymes signature (PS00187). FASTA results: Q59950 ACETOHYDROXY ACID SYNTHASE (EC 4.1.3.18) (612 aa) opt: 715; E(): 0; (28.5% ide (ilvB2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3465Rv3471chypothetical protein Rv3471c {Mycobacterium tuberculosis H37Rv (lab strain)}
3466Rv3472hypothetical protein Rv3472 {Mycobacterium tuberculosis H37Rv (lab strain)}
3467Rv3473c, (MTCY13E12.26c), len: 261. Probable bpoA. Some similarity to non-haem bromoperoxidase and related enzymes. May have been inactivated or truncated by neighbouring IS6110. FASTA results: BPA2_STRAU P29715 non-haem bromoperoxidase bpo-a2 (277 aa) opt: 237; (bpoA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3468Rv3474hypothetical protein Rv3474 {Mycobacterium tuberculosis H37Rv (lab strain)}
3469Rv3475hypothetical protein Rv3475 {Mycobacterium tuberculosis H37Rv (lab strain)}
3470Rv3476c, (MTCY13E12.29c), len: 449. kgtP, probable dicarboxylate transport protein. Contains sugar transport protein signatures 1 and 2 (PS00216, PS00217). FASTA results: Q52000 DICARBOXYLIC ACID TRANSPORT PROTEIN. 11/9 (429 aa)opt: 1086; E(): 0; 40.5% identity (kgtP) {Mycobacterium tuberculosis H37Rv (lab strain)}
3471Rv3477, (MTCY13E12.30), len: 98. Member of M. tuberculosis PE family including MTCI364.07, MTCY21C12.10c, MTCY1A11.25c, MTC1A11.04, MTCY359.33 etc. (PE class). FASTA results: sp|O05297|O05297 HYPOTHETICAL 9.6 KD PROTEIN (99 aa)opt: 394 z-score: 508.4 E(): 8.5e- (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3472Rv3478, (MTCY13E12.31), len: 393. Member of M. tuberculosis PPE family. Includes MTCY02B10.25c, MTCI364.08, MTCY10G2.10, MTCY03A2.22c, MTCY274.23c, MTCY164.34c, MTCY98.0029c, etc. FASTA scores: Z75555|MTCY02B10_25 Mycobacterium tuberculosis cosm (396 aa) opt: 2 (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3473Rv3479hypothetical protein Rv3479 {Mycobacterium tuberculosis H37Rv (lab strain)}
3474Rv3480chypothetical protein Rv3480c {Mycobacterium tuberculosis H37Rv (lab strain)}
3475Rv3481chypothetical protein Rv3481c {Mycobacterium tuberculosis H37Rv (lab strain)}
3476Rv3482chypothetical protein Rv3482c {Mycobacterium tuberculosis H37Rv (lab strain)}
3477Rv3483chypothetical protein Rv3483c {Mycobacterium tuberculosis H37Rv (lab strain)}
3478Rv3484, (MTCY13E12.37), len: 512. cpsA. Function: unknown, highly similar to Mycobacterium leprae protein CpsA. FASTA results: Q50160 CPSA (516 aa) opt: 2557; E(): 0; (74.9% identity in 518 aa overlap). Also similar to Z92771|MTCY71_7 Mycobacterium tuberculosis (cpsA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3479Rv3485chypothetical protein Rv3485c {Mycobacterium tuberculosis H37Rv (lab strain)}
3480Rv3486hypothetical protein Rv3486 {Mycobacterium tuberculosis H37Rv (lab strain)}
3481Rv3487c, (MTCY13E12.41c), len: 277. Function: unknown but similar to esterases and lipases of around 300 aa. Best with M. leprae protein Q50058. FASTA results: Q50058 COSMID B1740 (143 aa) opt: 565; E(): 3.9e-31; 61.8% identity in 136 aa overlap. Also similar to (lipF) {Mycobacterium tuberculosis H37Rv (lab strain)}
3482Rv3488hypothetical protein Rv3488 {Mycobacterium tuberculosis H37Rv (lab strain)}
3483Rv3489hypothetical protein Rv3489 {Mycobacterium tuberculosis H37Rv (lab strain)}
3484Rv3490, (MTCY13E12.43, otsA), len: 500. Function: probable alpha,alpha-trehalose-phosphate synthase (EC 2.4.1.15). FASTA results: Q50167 OTSA (498 aa) opt: 2706; E(): 0;(80.3% identity in 497 aa overlap) (otsA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3485Rv3491hypothetical protein Rv3491 {Mycobacterium tuberculosis H37Rv (lab strain)}
3486Rv3492chypothetical protein Rv3492c {Mycobacterium tuberculosis H37Rv (lab strain)}
3487Rv3493chypothetical protein Rv3493c {Mycobacterium tuberculosis H37Rv (lab strain)}
3488Rv3494chypothetical protein Rv3494c {Mycobacterium tuberculosis H37Rv (lab strain)}
3489Rv3495c, (MTV023.02c), len: 384. lprN, similar to Mycobacterium tuberculosis proteins MTCI28.13 (390 aa) and MTCY19H5.29 (402 aa) and (MTV051.08). Probably lipoprotein,contains possible signal sequence and appropriately positioned PS00013 Prokaryotic membrane li (lprN) {Mycobacterium tuberculosis H37Rv (lab strain)}
3490Rv3496chypothetical protein Rv3496c {Mycobacterium tuberculosis H37Rv (lab strain)}
3491Rv3497chypothetical protein Rv3497c {Mycobacterium tuberculosis H37Rv (lab strain)}
3492Rv3498chypothetical protein Rv3498c {Mycobacterium tuberculosis H37Rv (lab strain)}
3493Rv3499c, (MTV023.06c), len: 400. Member of Mycobacterium tuberculosis Mce protein family, similar to MTCY19H5.33c (404 aa), MTCI28.09 and MTV051.04 X70901|MTMCE_1 (432 aa). Contains a possible N-terminal signal sequence. FASTA scores: Z97182|MTCY19H5_33 Mycobact (mce4) {Mycobacterium tuberculosis H37Rv (lab strain)}
3494Rv3500chypothetical protein Rv3500c {Mycobacterium tuberculosis H37Rv (lab strain)}
3495Rv3501chypothetical protein Rv3501c {Mycobacterium tuberculosis H37Rv (lab strain)}
3496Rv3502chypothetical protein Rv3502c {Mycobacterium tuberculosis H37Rv (lab strain)}
3497Rv3503c, (MTV023.10c), len: 63. fdxD. Probable ferredoxin similar to several e.g. FER_CLOTH (63 aa). FASTA scores: sptr|Q49867|Q49867 HYPOTHETICAL 9.3 KD PROTEIN B229_C3(83 aa) opt: 276 z-score: 401.6 E(): 7.3e-15; 75.9% identity in 54 aa overlap; and sp|P00203| (fdxD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3498Rv3504, (MTV023.11), len: 400. fadE26. Probable acyl-CoA dehydrogenase similar to several e.g. Mycobacterium tuberculosis MTCY03C7.13 (387 aa), Archaeoglobus fulgidus AE001025_6 (387 aa).FASTA scores: Z82098|MTCY3C7_13 (387 aa)opt: 1031 z-score: 1231.1 E(): 0; (fadE26) {Mycobacterium tuberculosis H37Rv (lab strain)}
3499Rv3505, (MTV023.12), len: 373. fadE27. Probable acyl-CoA dehydrogenase similar to many e.g. Mycobacterium tuberculosis MTCY3C7.12 (339 aa). FASTA scores: Z82098|MTCY3C7_12 (339 aa) opt:497 z-score: 594.1 E(): 1.4e-25; 30.3% identity in 343 aa overlap. TBparse s (fadE27) {Mycobacterium tuberculosis H37Rv (lab strain)}
3500Rv3506, (MTV023.13), len: 502. fadD17, Probable Acyl-CoA Synthetase similar to many. FASTA scores: Z81360|MTCY4C12_34 Mycobacterium tuberculosis cosmi (532 aa) opt: 666z-score: 702.9 E(): 1.2e-31; 52.0% identity in 488 aa overlap. TBparse score is 0.898. Contai (fadD17) {Mycobacterium tuberculosis H37Rv (lab strain)}
3501Rv3507, (MTV023.14), len: 1381. Member of M. tuberculosis PE protein family, glycine-rich PGRS subfamily similar to many others e.g. MTCY493.04 (1329 aa). Contains two PS00583 pfkB family of carbohydrate kinases signature 1. FASTA scores:Z95844|MTCY493_4 Mycoba (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3502Rv3508, (MTV023.15), len: 1901. Member of Mycobacterium tuberculosis PE protein family, Gly-rich PGRS subfamily, most similar to MTV008_46 (1660 aa). Contains fivePS00583 pfkB family of carbohydrate kinases signatures 1. FASTA scores: AL0212|MTV008_46 (1660 aa) (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3503Rv3509c, (MTV023.16), len: 515. ilvB-3. Probable acetohydroxyacid synthase equivalent to Mycobacterium leprae protein described as Acetolactate synthase I, valine sensitive, large subunit U00020_36 (515 aa). Other M. tuberculosis proteins e.g. MTV012.17c, show b (ilvX) {Mycobacterium tuberculosis H37Rv (lab strain)}
3504Rv3510chypothetical protein Rv3510c {Mycobacterium tuberculosis H37Rv (lab strain)}
3505Rv3511, (MTV023.18), len: 714. Member of Mycobacterium tuberculosis PE protein family, Gly-rich PGRS subfamily, most similar to MTV008_46 (1660 aa). FASTA scores: AL0212|MTV008_46Mycobacterium tuberculosis sequenc (1660 aa) opt:2383 z-score: 1406.6 E(): 0; 49.5 (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3506Rv3512Protein sequence is in conflict with the conceptual translation; Rv3512, (MTV023.19), len:1059. Frameshifted PGRS, could be continuation of MTV023.18, but no error could be found. FASTA scores: Z95844|MTCY493_4 Mycobacterium tuberculosis cosmid (1329 aa) (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3507Rv3513c, (MTV023.20c), len: 218. fadD18. Similar toC-terminal fragment of Acyl-CoA Synthetase, almost identical to C-terminal end of MTV023.22c. Probably result of partial gene duplication, start uncertain. Also highly similar to C-terminal part (150 aa) of Myco (fadD18) {Mycobacterium tuberculosis H37Rv (lab strain)}
3508Rv3514, (MTV023.21), len: 1489. Member of Mycobacterium tuberculosis PE protein family, Gly-rich PGRS subfamily, most similar to MTV008_46 (1660 aa). FASTA scores: AL0212|MTV008_46 (1660 aa) opt: 4859 z-score: 2609.6 E(): 0;52.0% identity in 1643 aa overlap. TB (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3509Rv3515c, (MTV023.22c), len: 548. fadD19. Probable Acyl-CoA Synthetase similar to many e.g. P29212|LCFA_ECOLI (561 aa). Also highly similar to products of two adjacent orfs from Mycobacterium avium encoding secreted 30 kD antigenprecursor Mig MAU43598_2 (262 aa) (fadD19) {Mycobacterium tuberculosis H37Rv (lab strain)}
3510Rv3516, (MTV023.23), len: 263. echA19. Probable enoyl coA hydratase similar to several e.g. P76082|ECHH_ECOLI, closest to MTCY08D5.17 (262 aa). FASTA scores: sp|P76082|ECHH_ECOLI PROBABLE ENOYL-COA HYDRATASE (EC (255 aa) opt:523 z-score: 642.4 E(): 2.9e-28; 33. (echA19) {Mycobacterium tuberculosis H37Rv (lab strain)}
3511Rv3517hypothetical protein Rv3517 {Mycobacterium tuberculosis H37Rv (lab strain)}
3512Rv3518chypothetical protein Rv3518c {Mycobacterium tuberculosis H37Rv (lab strain)}
3513Rv3519hypothetical protein Rv3519 {Mycobacterium tuberculosis H37Rv (lab strain)}
3514Rv3520chypothetical protein Rv3520c {Mycobacterium tuberculosis H37Rv (lab strain)}
3515Rv3521hypothetical protein Rv3521 {Mycobacterium tuberculosis H37Rv (lab strain)}
3516Rv3522hypothetical protein Rv3522 {Mycobacterium tuberculosis H37Rv (lab strain)}
3517Rv3523hypothetical protein Rv3523 {Mycobacterium tuberculosis H37Rv (lab strain)}
3518Rv3524hypothetical protein Rv3524 {Mycobacterium tuberculosis H37Rv (lab strain)}
3519Rv3525chypothetical protein Rv3525c {Mycobacterium tuberculosis H37Rv (lab strain)}
3520Rv3526hypothetical protein Rv3526 {Mycobacterium tuberculosis H37Rv (lab strain)}
3521Rv3527hypothetical protein Rv3527 {Mycobacterium tuberculosis H37Rv (lab strain)}
3522Rv3528chypothetical protein Rv3528c {Mycobacterium tuberculosis H37Rv (lab strain)}
3523Rv3529chypothetical protein Rv3529c {Mycobacterium tuberculosis H37Rv (lab strain)}
3524Rv3530chypothetical protein Rv3530c {Mycobacterium tuberculosis H37Rv (lab strain)}
3525Rv3531chypothetical protein Rv3531c {Mycobacterium tuberculosis H37Rv (lab strain)}
3526Rv3532, (MTCY03C7.24c), len: 406 aa. Member of M. tuberculosis PPE protein family similar to eg AL022021|MTV049_28 Mycobacterium tuberculosis seque (403 aa) fasta scores, opt: 931 z-score: 865.6 E(): 0; 43.4% identity in 410 aa overlap (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3527Rv3533c, (MTCY03C7.23), len: 582 aa. Member of M. tuberculosis PPE protein family, similar to eg AL021646|MTV014_3 Mycobacterium tuberculosis sequen (590 aa) opt: 2289 z-score: 1849.1 E(): 0; 63.5% identity in 600 aa overlap) (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3528Rv3534chypothetical protein Rv3534c {Mycobacterium tuberculosis H37Rv (lab strain)}
3529Rv3535chypothetical protein Rv3535c {Mycobacterium tuberculosis H37Rv (lab strain)}
3530Rv3536chypothetical protein Rv3536c {Mycobacterium tuberculosis H37Rv (lab strain)}
3531Rv3537hypothetical protein Rv3537 {Mycobacterium tuberculosis H37Rv (lab strain)}
3532Rv3538, (MTCY03C7.18c), len: 286 aa. ufa2. Unknown Fatty Acid Methyltransferase, similar to G886104 cyclopropane mycolic acid synthase (CMA1) (290 aa), fasta scores, opt: 609, E(): 1.9e-31, (39.6% identity in 285 aa overlap) (ufaA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3533Rv3539, (MTCY03C7.17c), len: 479 aa. Member of M. tuberculosis PE protein family, similar to AL022021|MTV049_21 Mycobacterium tuberculosis seque (655 aa) fasta scores, opt: 914 z-score: 1032.0 E(): 0; 37.3% identity in 498 aa overlap) (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3534Rv3540c, (MTCY03C7.16), len: 386 aa. Probable lipid-transfer protein Similar to eg G304423 non-specific lipid-transfer protein (sterol carrier protein) (547 aa), fasta scores, opt: 381, E(): 1e-17, (27.5% identity in 389 aa overlap) and to sp|O30255|O30255 3-KET (ltp2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3535Rv3541chypothetical protein Rv3541c {Mycobacterium tuberculosis H37Rv (lab strain)}
3536Rv3542chypothetical protein Rv3542c {Mycobacterium tuberculosis H37Rv (lab strain)}
3537Rv3543c, (MTCY03C7.13), len: 387 aa. fadE29. Acyl-CoA Dehydrogenase similar to eg ACDB_BACSU P45857 acyl-coa dehydrogenase, (379 aa), fasta scores, opt: 440, E(): 3.4e-21, (29.2% identity in 390 aa overlap) (fadE29) {Mycobacterium tuberculosis H37Rv (lab strain)}
3538Rv3544c, (MTCY03C7.12), len: 339 aa. fadE28. Acyl-CoA Dehydrogenase, similar to eg ACD_MYCLE P46703 acyl-coa dehydrogenase (389 aa), fasta scores, opt: 165, E(): 0.0012,(25.2% identity in 345 aa overlap) (fadE28) {Mycobacterium tuberculosis H37Rv (lab strain)}
3539Rv3545chypothetical protein Rv3545c {Mycobacterium tuberculosis H37Rv (lab strain)}
3540Rv3546, (MTCY03C7.10c), len: 391 aa. fadA5, Acetyl-CoA C-Acetyltransferase, similar to eg THIL_CHRVI P45369 acetyl-coa acetyltransferase (394 aa), fasta scores, opt: 790, E(): 0, (39.0% identity in 403 aa overlap); contains PS00737 Thiolases signature 2 (fadA5) {Mycobacterium tuberculosis H37Rv (lab strain)}
3541Rv3547hypothetical protein Rv3547 {Mycobacterium tuberculosis H37Rv (lab strain)}
3542Rv3548chypothetical protein Rv3548c {Mycobacterium tuberculosis H37Rv (lab strain)}
3543Rv3549chypothetical protein Rv3549c {Mycobacterium tuberculosis H37Rv (lab strain)}
3544Rv3550, (MTCY03C7.06c), len: 247. echA20, Enoyl-CoAHydratase/Isomerase Superfamily. CRT_CLOAB P52046 3-hydroxbutyryl-coa dehydratase (ec 4. (261 aa), fasta scores, opt:321, E(): 9.2e-15, (34.0% identity in 209 aa overlap) (echA20) {Mycobacterium tuberculosis H37Rv (lab strain)}
3545Rv3551hypothetical protein Rv3551 {Mycobacterium tuberculosis H37Rv (lab strain)}
3546Rv3552hypothetical protein Rv3552 {Mycobacterium tuberculosis H37Rv (lab strain)}
3547Rv3553hypothetical protein Rv3553 {Mycobacterium tuberculosis H37Rv (lab strain)}
3548Rv3554, (MTCY06G11.01-MTCY03C7.01c), len: 685.fdxB,Possible electron transfer protein. Unknown two-domain protein. N-terminal part is similar to sp|P73428|P73428 HYPOTHETICAL 36.2 KD PROTEIN (312 aa) fasta scores, opt: 317z-score: 373.6 E(): 2.8e-13; 30.2% iden (fdxB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3549Rv3555chypothetical protein Rv3555c {Mycobacterium tuberculosis H37Rv (lab strain)}
3550Rv3556c, (MTCY06G11.03), len: 386 aa. fadA6. Acetyl-CoA C-Acetyltransferase, similar to eg sp|P45359|THL_CLOABACETYL-COA ACETYLTRANSFERASE (392 aa) fasta scores, opt:872 z-score: 1016.0 E(): 0; 38.1% identity in 396 aa overlap; THIL_HAEIN P44873 acetyl-coa acety (fadA6) {Mycobacterium tuberculosis H37Rv (lab strain)}
3551Rv3557chypothetical protein Rv3557c {Mycobacterium tuberculosis H37Rv (lab strain)}
3552Rv3558, (MTCY06G11.05), unknown function, len: 552 aa, member of the M. tuberculosis PPE family of glycine-rich proteins similar to eg Z82098|MTCY3C7_23 Mycobacterium tuberculosis cosmid (582 aa) fasta scores opt: 1908 z-score: 1648.4 E(): 0; 58.5% identity in (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3553Rv3559chypothetical protein Rv3559c {Mycobacterium tuberculosis H37Rv (lab strain)}
3554Rv3560c, (MTCY06G11.07c), len: 385. fadE30, Acyl-coa dehydrogenase, similar to eg ACDS_MOUSE Q07417 acyl-coa dehydrogenase, short-chain s (412 aa), fasta scores, opt: 417, E():6.1e-21,(29.5% identity in 359 aa overlap) (fadE30) {Mycobacterium tuberculosis H37Rv (lab strain)}
3555Rv3561, (MTCY06G11.08), len: 507. fadD3, Probable fatty-acid coA ligase, similar to e.g. LCFA_ECOLIP29212 long-chain-fatty-acid--coa ligase (561 aa), fasta scores, opt: 532, E(): 6.3e-28, (30.0% identity in 533 aa overlap) ; contains PS00455 Putative AMP-bindin (fadD3) {Mycobacterium tuberculosis H37Rv (lab strain)}
3556Rv3562, (MTCY06G11.09), len: 377. fadE31, Probable acyl-coA dehydrogenase, similar e.g. to ACDA_BACSUP45867 acyl-coa dehydrogenase (ec 1.3.99.-). (379 aa), fasta scores,opt: 347, E(): 1e-15, (28.6% identity in 385 aa overlap) (fadE31) {Mycobacterium tuberculosis H37Rv (lab strain)}
3557Rv3563, (MTCY06G11.10), len: 319. Probable acyl-coadehydrogenase, similar to ACDB_BACSU P45857 acyl-coa dehydrogenase (ec 1.3.99.-). (379 aa), fasta scores, opt: 230, E(): 1.1e-07, (25.5% identity in 357 aa overlap) (fadE32) {Mycobacterium tuberculosis H37Rv (lab strain)}
3558Rv3564, (MTCY06G11.11), len: 318. Probable acyl-coadehydrogenase, similar to eg ACDB_BACSUP45857 acyl-coa dehydrogenase (ec 1.3.99.-). (379 aa), fasta scores, opt: 211,E(): 4.7e-06, (25.9% identity in 378 aaoverlap) (fadE33) {Mycobacterium tuberculosis H37Rv (lab strain)}
3559Rv3565, (MTCY06G11.12), len: 388. aspB, possible aminotransferase, similar to eg AAT1_BACSUP53001 aspartate aminotransferase (ec 2.6.1. (393 aa), fasta scores, opt: 519,E():1.9e-26, (26.5% identity in 389 aaoverlap); contains PS00105 Aminotransferases class-I p (aspB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3560Rv3566c, (MTCY06G11.13c), len: 332. Similar in N-terminus to e.g. NHOA_SALTY Q00267 n-hydroxyarylamine o-acetyltransferas (281 aa), fasta scores, opt: 507, E(): 2.6e-26,(34.8% identity in 273 aa overlap), reading frame open upstream of homology to position15234 (nhoA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3561Rv3567chypothetical protein Rv3567c {Mycobacterium tuberculosis H37Rv (lab strain)}
3562Rv3568chypothetical protein Rv3568c {Mycobacterium tuberculosis H37Rv (lab strain)}
3563Rv3569chypothetical protein Rv3569c {Mycobacterium tuberculosis H37Rv (lab strain)}
3564Rv3570chypothetical protein Rv3570c {Mycobacterium tuberculosis H37Rv (lab strain)}
3565Rv3571hypothetical protein Rv3571 {Mycobacterium tuberculosis H37Rv (lab strain)}
3566Rv3572hypothetical protein Rv3572 {Mycobacterium tuberculosis H37Rv (lab strain)}
3567Rv3573c, (MTCY06G11.20c), len: 711. fadE34, Similar, especially in C-terminal half to acyl coA dehydrogenases eg ACDM_PIG P41367 acyl-coa dehydrogenase, medium-chain specific precursor (421 aa), fasta scores, opt: 325, E(): 4.9e-13, (28.5% identity in 368 aa ove (fadE34) {Mycobacterium tuberculosis H37Rv (lab strain)}
3568Rv3574hypothetical protein Rv3574 {Mycobacterium tuberculosis H37Rv (lab strain)}
3569Rv3575chypothetical protein Rv3575c {Mycobacterium tuberculosis H37Rv (lab strain)}
3570Rv3576, (MTCY06G11.23), len: 237. Unknown, similar to c-terminal half of K08G_MYCTU Q11053 Rv1266c (MTCY50.16), probable serine/threonine-protein kinase (626 aa), fasta scores, opt: 397, E(): 3.5e-20, (36.5% identity in 200 aa overlap), also to KY28_MYCTU;, con (pknM) {Mycobacterium tuberculosis H37Rv (lab strain)}
3571Rv3577hypothetical protein Rv3577 {Mycobacterium tuberculosis H37Rv (lab strain)}
3572Rv3578, (MTCY06G11.25), arsB, len: 413. Probable arsenical pump membrane protein, similar to eg ARB2_ECOLI P52146 arsenical pump membrane protein. esch (429 aa), fasta scores, opt: 345, E(): 3.8e-15, (29.6% identity in426 aa overlap) (arsB2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3573Rv3579chypothetical protein Rv3579c {Mycobacterium tuberculosis H37Rv (lab strain)}
3574Rv3580c, (MTCY06G11.27c), cysS, len: 469. Cysteinyl-trna synthetase, similar to eg SYC_ECOLI P21888 cysteinyl-trna synthetase (461 aa), fasta scores, opt: 1189, E(): 0,(42.8% identity in 463 aa overlap) (cysS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3575Rv3581chypothetical protein Rv3581c {Mycobacterium tuberculosis H37Rv (lab strain)}
3576Rv3582chypothetical protein Rv3582c {Mycobacterium tuberculosis H37Rv (lab strain)}
3577Rv3583chypothetical protein Rv3583c {Mycobacterium tuberculosis H37Rv (lab strain)}
3578Rv3584, (MTV024.02), len: 182. Unknown. Contains probable N-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site. TBparse score is 0.895 (lpqE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3579Rv3585, (MTV024.03), radA, len: 480. Probable DNA REPAIR PROTEIN RADA homolog, similar to many, e.g. sp|P37572|RADA_BACSU DNA REPAIR PROTEIN RADA HOMOLOG (YACJ)(458 aa);FASTA scores: opt: 1204 z-score: 1366.1 E(): 0; 39.6% identity in455aa overlap. Contains PS0 (radA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3580Rv3586hypothetical protein Rv3586 {Mycobacterium tuberculosis H37Rv (lab strain)}
3581Rv3587chypothetical protein Rv3587c {Mycobacterium tuberculosis H37Rv (lab strain)}
3582Rv3588chypothetical protein Rv3588c {Mycobacterium tuberculosis H37Rv (lab strain)}
3583Rv3589, (MTV024.07), len: 304. Probable DNA GLYCOSYLASE, similar to many e.g. sp|Q05869|MUTY_SALTY A/G-SPECIFIC ADENINE GLYCOSYLASE (350 aa); opt:421 z-score: 496.6 E(): 3.8e-20;35.2% identity in 227 aa overlap.TBparse score is0.905 (mutY) {Mycobacterium tuberculosis H37Rv (lab strain)}
3584Rv3590c, (MTV024.08c,MTCY6F7.04), len: 584. Belongs to M. tuberculosis Gly-rich protein family (PE-PGRS family)highly similar to e.g.gp|AL0210|MTV006_15 M. tuberculosis(562 aa); FASTA scores: opt: 814 z-score: 532.1 E(): 4e-22; 58.2% identity in 232 aa overlap (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3585Rv3591chypothetical protein Rv3591c {Mycobacterium tuberculosis H37Rv (lab strain)}
3586Rv3592hypothetical protein Rv3592 {Mycobacterium tuberculosis H37Rv (lab strain)}
3587Rv3593, (MTCY6F7.01c), len: 491. Unknown. ContainsN-terminal signal sequence and appropriately positioned PS00013 Prokaryotic membrane lipoprotein lipid attachment site (lpqF) {Mycobacterium tuberculosis H37Rv (lab strain)}
3588Rv3594hypothetical protein Rv3594 {Mycobacterium tuberculosis H37Rv (lab strain)}
3589Rv3595c, (MTCY07H7B.27), len: 439. Belongs to PGRS(PE) family, similar to eg Y03A_MYCTU Q10637 hypothetical glycine-rich 49.6 kd protein (603 aa), fasta scores, opt: 1522, E(): 0, (56.1% identity in 471 aa overlap) (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3590Rv3596c, (MTCY07H7B.26), clpC, len: 848. Probable atp-dependent clp protease atp-binding subunit, highly similar to members of the clpA/clpB family, e.g. MECB_BACSU P37571 negative regulator of genetic competence mecB (810 aa),fasta scores, opt: 2969, E(): 0, (6 (clpC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3591Rv3597c, (MTCY07H7B.25), lsr2, len: 112. lsr2 homologue, highly similar to M.leprae LSR2_MYCLE P24094 lsr2 protein precursor (15 kd antigen) (112 aa), fasta scores, opt:698, E(): 0, (92.9% identity in 112 aa overlap) (lsr2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3592Rv3598c, (MTCY07H7B.24), lysS, len: 505. Lysyl-trnasynthetase, similar to e.g. SYK_BACSU P37477 lysyl-trna synthetase (ec 6.1.1.6) (499 aa), fasta scores, opt: 1294, E(): 0, (42.4% identity in 498 aa overlap); contains PS00179Aminoacyl-transfer RNA synthetases c (lysS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3593Rv3599chypothetical protein Rv3599c {Mycobacterium tuberculosis H37Rv (lab strain)}
3594Rv3600chypothetical protein Rv3600c {Mycobacterium tuberculosis H37Rv (lab strain)}
3595Rv3601c, (MTCY07H7B.21), panD, len: 139. Aspartate1-decarboxylase, similar to eg PAND_BACSU P52999, aspartate1-decarboxylase (127 aa), fasta scores, opt: 421, E(): 6.7e-23, (54.5% identity in 123 aa overlap) (panD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3596Rv3602c, (MTCY07H7B.20), panC, len: 309. Pantoate--beta-alanine ligase, similar to eg PANC_ECOLI P31663 pantoate--beta-alanine ligase (283 aa), fasta scores,opt: 695, E(): 0, (46.1% identity in 271 aa overlap) (panC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3597Rv3603chypothetical protein Rv3603c {Mycobacterium tuberculosis H37Rv (lab strain)}
3598Rv3604chypothetical protein Rv3604c {Mycobacterium tuberculosis H37Rv (lab strain)}
3599Rv3605chypothetical protein Rv3605c {Mycobacterium tuberculosis H37Rv (lab strain)}
3600Rv3606c, (MTCY07H7B.16), folK, len: 188. Probable 2-amino-4-hydroxy-6-hydroxymethyldihydropterine pyrophosphokinase, similar to many e.g. HPPK_BACSU P29252 2-amino-4-hydroxy-6-hydroxymethyldihydropterine pyrophosphokinase (EC 2.7.6.3) (167 aa) FIRST STEP IN DIHY (folK) {Mycobacterium tuberculosis H37Rv (lab strain)}
3601Rv3607c, (MTCY07H7B.15), len: 133. folX, similar toeg YACE_BACSU P28823 hypothetical 13.5 kd protein in sul-f(120aa), fasta scores, opt: 283, E(): 2.5e-13, (39.0% identityin 118 aa overlap) (folX) {Mycobacterium tuberculosis H37Rv (lab strain)}
3602Rv3608c, (MTCY07H7B.14), folP, len: 280. Dihydropteroate synthase, similar to e.g. DHPS_ECOLI P26282 dihydropteroate synthase (ec 2.5.1.15 SECOND STEP IN DIHYDROFOLATE BIOSYNTHESIS(282 aa), fasta scores, opt:642, E(): 0, (42.0%identity in 274 aa overlap); contai (folP) {Mycobacterium tuberculosis H37Rv (lab strain)}
3603Rv3609c, (MTCY07H7B.13), folE, len: 202. GTP cyclohydrolase I, similar to e.g. GCH1_BACSU P19465 gtp cyclohydrolase i (ec 3.5.4.16) FIRST STEP INTHE BIOSYNTHESIS OF TETRAHYDROFOLATE (190 aa), fasta scores, opt: 750, E(): 0, (58.9% identity in 190 aa overlap); co (folE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3604Rv3610c, (MTCY07H7B.12), ftsH, len: 760.cell division protein ftsh, Similar to e.g. FTSH_BACSU P37476 cell division protein ftsh homolog (637 aa), fasta scores, opt: 1897, E(): 0, (49.0% identity in 622 aa overlap), contains PS00017 ATP/GTP-binding site motif A, (ftsH) {Mycobacterium tuberculosis H37Rv (lab strain)}
3605Rv3611hypothetical protein Rv3611 {Mycobacterium tuberculosis H37Rv (lab strain)}
3606Rv3612chypothetical protein Rv3612c {Mycobacterium tuberculosis H37Rv (lab strain)}
3607Rv3613chypothetical protein Rv3613c {Mycobacterium tuberculosis H37Rv (lab strain)}
3608Rv3614chypothetical protein Rv3614c {Mycobacterium tuberculosis H37Rv (lab strain)}
3609Rv3615chypothetical protein Rv3615c {Mycobacterium tuberculosis H37Rv (lab strain)}
3610Rv3616chypothetical protein Rv3616c {Mycobacterium tuberculosis H37Rv (lab strain)}
3611Rv3617, (MTCY07H7B.05c-MTCY15C10.35c), ephA, len: 322. Similar to C-terminus of e.g. HYES_RAT P80299 soluble epoxide hydrolase (seh) (554aa), fasta scores, opt: 759, E(): 0, (40.5% identity in 306aa overlap); contains PS00888 Cyclic nucleotide-binding domain si (ephA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3612Rv3618hypothetical protein Rv3618 {Mycobacterium tuberculosis H37Rv (lab strain)}
3613Rv3619chypothetical protein Rv3619c {Mycobacterium tuberculosis H37Rv (lab strain)}
3614Rv3620chypothetical protein Rv3620c {Mycobacterium tuberculosis H37Rv (lab strain)}
3615Rv3621c, (MTCY15C10.31,MTCY07H7B.01), len: 413. Member of Ala-, Gly-rich protein family in M. tuberculosis (PPE family). FASTA best: Q10813 YX23_MYCTU HYPOTHETICAL 41.1KD PROTEIN CY27 (404 aa) opt: 939 z-score: 914.2 E(): 0; (44.5% identity in 418 aa overlap) (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3616Rv3622c, (MTCY15C10.30), len: 99. Belongs to largefamily of M. tuberculosis proteins. (PE) family), but no glycin rich c-terminus present, FASTA best: Q10637 Y03A_MYCTU(603 aa) opt: 252z-score: 301.9 E(): 3.1e-10; (46.9% identity in 98 aaoverlap) (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3617Rv3623, (MTCY15C10.29c), len: 240. Probable lipoprotein, has suitable signal peptide and prokaryotic membranelipoprotein lipid attachment site (PS00013). Some similarityto hypothetical E. coli protein. FASTA best: P11668 YGGE_ECOLI (246 aa) opt: 206 z-score: 23 (lpqG) {Mycobacterium tuberculosis H37Rv (lab strain)}
3618Rv3624c, (MTCY15C10.28), len: 216. Function: hpt, probable hypoxanthine-guanine phosphoribosyltransferase (butseems to have 35 aa extension at N-terminus) involved in purine salvage contains PS00103 Purine/pyrimidine phosphoribosyltransferases signature. FASTA b (hpt) {Mycobacterium tuberculosis H37Rv (lab strain)}
3619Rv3625c, (MTCY15C10.27), len: 323. Function: unknown but shows some similarity to bacterial cell cycle proteins, MesJ, best with E. coli. FASTA best: P52097 MESJ_ECOLI (432 aa) opt:299 z-score: 351.6 E(): 5.2e-13; (34.7% identity in 277 aaoverlap) (mesJ) {Mycobacterium tuberculosis H37Rv (lab strain)}
3620Rv3626chypothetical protein Rv3626c {Mycobacterium tuberculosis H37Rv (lab strain)}
3621Rv3627chypothetical protein Rv3627c {Mycobacterium tuberculosis H37Rv (lab strain)}
3622Rv3628, (MTCY15C10.24), ppa, len: 162. Function: probable inorganic pyrophosphatase (pyrophosphate phosphohydrolase EC 3.6.1.1), highly similar to many bacterial enzymes, especially to that of Sulfulobus acidocaldarius. FASTA best: P50308IPYR_SULAC INORGANIC PY (ppa) {Mycobacterium tuberculosis H37Rv (lab strain)}
3623Rv3629chypothetical protein Rv3629c {Mycobacterium tuberculosis H37Rv (lab strain)}
3624Rv3630hypothetical protein Rv3630 {Mycobacterium tuberculosis H37Rv (lab strain)}
3625Rv3631hypothetical protein Rv3631 {Mycobacterium tuberculosis H37Rv (lab strain)}
3626Rv3632hypothetical protein Rv3632 {Mycobacterium tuberculosis H37Rv (lab strain)}
3627Rv3633hypothetical protein Rv3633 {Mycobacterium tuberculosis H37Rv (lab strain)}
3628Rv3634c, (MTCY15C10.18), len: 314. Function: possible DTDP-Glucose 4,6-dehydratase (EC 4.2.1.46) related to many bacterial dehydratases especially the DTDP-Glucose 4,6-dehydratase - of Streptomyces griseus (P29782). Contains short-chain alcohol dehydrogenase fam (rmlB2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3629Rv3635hypothetical protein Rv3635 {Mycobacterium tuberculosis H37Rv (lab strain)}
3630Rv3636hypothetical protein Rv3636 {Mycobacterium tuberculosis H37Rv (lab strain)}
3631Rv3637hypothetical protein Rv3637 {Mycobacterium tuberculosis H37Rv (lab strain)}
3632Rv3638hypothetical protein Rv3638 {Mycobacterium tuberculosis H37Rv (lab strain)}
3633Rv3639chypothetical protein Rv3639c {Mycobacterium tuberculosis H37Rv (lab strain)}
3634Rv3640chypothetical protein Rv3640c {Mycobacterium tuberculosis H37Rv (lab strain)}
3635Rv3641c, (MTCY15C10.11), fic, len: 211. Function: unknown but resembles E. coli Fic Protein that causes cell filamentation and may be involved in cell division. FASTA best: P20605 FIC_ECOLI (200 aa) opt: 323 z-score: 413.9 E():1.8e-16; (31.0%identity in 187 aa o (fic) {Mycobacterium tuberculosis H37Rv (lab strain)}
3636Rv3642chypothetical protein Rv3642c {Mycobacterium tuberculosis H37Rv (lab strain)}
3637Rv3643hypothetical protein Rv3643 {Mycobacterium tuberculosis H37Rv (lab strain)}
3638Rv3644chypothetical protein Rv3644c {Mycobacterium tuberculosis H37Rv (lab strain)}
3639Rv3645hypothetical protein Rv3645 {Mycobacterium tuberculosis H37Rv (lab strain)}
3640Rv3646c, (MTCY15C10.06), topA, len: 934, DNA topoisomerase I, highly similar to many e.g. TOP1_ECOLI P06612 dna topoisomerase i (ec 5.99.1.2) (865 aa), fasta scores; opt: 397 z-score: 1472.5 E(): 0, 39.6% identity in 704 aa overlap. Some conflicts with TOP1_MYCT (topA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3641Rv3647chypothetical protein Rv3647c {Mycobacterium tuberculosis H37Rv (lab strain)}
3642Rv3648c, (MTCY15C10.04), cspA. len: 67. Function: cold shock protein containing cold-shock DNA-binding domain signature (PS00352) at N-terminus. Closest relative is cold shock protein from Arthrobacter globiformis (ARGCSP_1).FASTA best:ARGCSP_1 opt: 335 z-score: (cspA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3643Rv3649hypothetical protein Rv3649 {Mycobacterium tuberculosis H37Rv (lab strain)}
3644Rv3650, (MTCY15C10.02c), len: 94. Function: unknownbut related to several other M. tuberculosis proteins of the PE family but without the repetitive gly-rich region. FASTA best: Q10637 Y03A_MYCTU (603 aa) opt: 313 z-score: 370.1 E(): 4.9e-14 (66.7% identity in (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3645Rv3651hypothetical protein Rv3651 {Mycobacterium tuberculosis H37Rv (lab strain)}
3646Rv3652, (MTV025.001A), len: 54. Member of the PGRS(PE) glycine-rich protein family of M. tuberculosis, similarto many e.g. Y03A_MYCTU Q10637 hypothetical glycine-rich49.6 kd pro (603 aa), Fasta scores; opt: 239, E(): 1.8e-15, 77.4% identityin 53 aa overlap. Not (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3647Rv3653Protein sequence is in conflict with the conceptual translation; Rv3653, (MTV025.001B), len: 245. Unknown, highly similar to the C-termini of members the PGRS glycine-rich protein family of M. tuberculosis, e.g. gp|AL0089|MTV002_7 M.tuberculosis sequence( (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3648Rv3654chypothetical protein Rv3654c {Mycobacterium tuberculosis H37Rv (lab strain)}
3649Rv3655chypothetical protein Rv3655c {Mycobacterium tuberculosis H37Rv (lab strain)}
3650Rv3656chypothetical protein Rv3656c {Mycobacterium tuberculosis H37Rv (lab strain)}
3651Rv3657chypothetical protein Rv3657c {Mycobacterium tuberculosis H37Rv (lab strain)}
3652Rv3658chypothetical protein Rv3658c {Mycobacterium tuberculosis H37Rv (lab strain)}
3653Rv3659c, (MTV025.007c), len: 352. Unknown, but similar to trbB: probable conjugal transfer protein from EAU67194_28 Enterobacter aerogenes and AE000068_7 Rhizobium sp.Also similar to KILB PROTEIN. FASTA scores: p|X59971|ECRK2KILB_1 E.coli plasmid RK2 kilB gene.( (trbB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3654Rv3660chypothetical protein Rv3660c {Mycobacterium tuberculosis H37Rv (lab strain)}
3655Rv3661hypothetical protein Rv3661 {Mycobacterium tuberculosis H37Rv (lab strain)}
3656Rv3662chypothetical protein Rv3662c {Mycobacterium tuberculosis H37Rv (lab strain)}
3657Rv3663c, (MTV025.011c), len: 548. dppD, Probable peptidetransport system ABC-transporter ATP-binding protein similar to many, e.g.gp|AF0354|AF035413_11 Agrobacterium tumefaciens AgaA, (588 aa), FASTA scores: opt: 1354 z-score: 1473.2 E(): 0, 42.9% identity in 54 (dppD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3658Rv3664c, (MTV025.012c), len: 266. dppC, Probable peptidetransport system permease, similar to many, e.g. gp|U64514|BFU64514_3 Bacillus firmus dppABC operon, di (304aa), FASTAscores: opt: 642 z-score: 800.3 E(): 0, 35.7% identityin263 aa overlap. Also similar to (dppC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3659Rv3665c, (MTV025.013c), len: 308. dppB, Probable peptidetransport system permease, similar to many, e.g. gp|AF0354|AF035413_3 Agrobacterium tumefaciens AgaA, A (323 aa),FASTA scores: opt: 657 z-score: 801.6 E(): 0. 34.0% identityin 309 aa overlap, also similar t (dppB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3660Rv3666c, (MTV025.014c), len: 541. dppA, Probable peptidetransport system secreted peptide-binding protein similar to many e.g. gp|X04194|STOPPAG_1 Salmonella typhimuriumOppAgene f (542aa) FASTA scores: opt: 474 z-score: 538.0 E():1.9e-22,27.9% identity in 523 aa (dppA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3661Rv3667, (MTV025.015), acs, len: 651. Probable acetyl-coenzyme-A synthetase, similar to many, e.g. ACSA_ECOLI P27550 acetyl-coenzyme a synthetase (652 aa), fasta scores;opt: 1625 z-score: 2198.0 E(): 0, 48.3% identity in 646 aaoverlap. Contains PS00455 Putative (acs) {Mycobacterium tuberculosis H37Rv (lab strain)}
3662Rv3668chypothetical protein Rv3668c {Mycobacterium tuberculosis H37Rv (lab strain)}
3663Rv3669hypothetical protein Rv3669 {Mycobacterium tuberculosis H37Rv (lab strain)}
3664Rv3670, (MTV025.018), len: 327, ephE, Probable epoxide hydrolase similar to many, involved in detoxification,aromatic hydrocarbons catabolism. FASTA scores: gp|D85082|D85082_23 Bacillus subtilis DNA, genome sequ (286 aa)opt: 311 z-score: 364.3 E(): 8.9e-13, 29. (ephE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3665Rv3671chypothetical protein Rv3671c {Mycobacterium tuberculosis H37Rv (lab strain)}
3666Rv3672chypothetical protein Rv3672c {Mycobacterium tuberculosis H37Rv (lab strain)}
3667Rv3673chypothetical protein Rv3673c {Mycobacterium tuberculosis H37Rv (lab strain)}
3668Rv3674c, (MTV025.022c), nth, len: 223. Probable Endonuclease III, (DNA N-GLYCOSYLASE ACTIVITY), similar to many, e.g. sp|P73715|END3_SYNY3 ENDONUCLEASE III (219 aa) FASTA scores: opt: 678 z-score: 839.3 E(): 0. 53.6% identity in 194 aa overlap, or sp|P46303|UVEN (nth) {Mycobacterium tuberculosis H37Rv (lab strain)}
3669Rv3675hypothetical protein Rv3675 {Mycobacterium tuberculosis H37Rv (lab strain)}
3670Rv3676hypothetical protein Rv3676 {Mycobacterium tuberculosis H37Rv (lab strain)}
3671Rv3677chypothetical protein Rv3677c {Mycobacterium tuberculosis H37Rv (lab strain)}
3672Rv3678chypothetical protein Rv3678c {Mycobacterium tuberculosis H37Rv (lab strain)}
3673Rv3679hypothetical protein Rv3679 {Mycobacterium tuberculosis H37Rv (lab strain)}
3674Rv3680hypothetical protein Rv3680 {Mycobacterium tuberculosis H37Rv (lab strain)}
3675Rv3681c, (MTV025.029c), len: 100. Probable regulatory protein, similar to many e.g. gp|X62287|SCWHIB_1 S.coelicolor whiBgene (87 aa), FASTA scores: opt: 237 z-score: 332.1 E():5.5e-11; 45.2% identity in 73 aa overlap,Also similar to several mycobacterial putativ (whiB4) {Mycobacterium tuberculosis H37Rv (lab strain)}
3676Rv3682, (MTV025.030), ponA, len: 810. CLASS A PENICILLIN-BINDING PROTEIN, almost identical to gp|S82044|S82044_1 pon1=PBP1 Mycobacterium leprae,(821 aa), FASTA scores:opt: 4547 z-score: 3629.2 E(): 0, 88.0% identity in 769 aaoverlap. Also similar to MTCY21D4_13 (ponA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3677Rv3683hypothetical protein Rv3683 {Mycobacterium tuberculosis H37Rv (lab strain)}
3678Rv3684hypothetical protein Rv3684 {Mycobacterium tuberculosis H37Rv (lab strain)}
3679Rv3685chypothetical protein Rv3685c {Mycobacterium tuberculosis H37Rv (lab strain)}
3680Rv3686chypothetical protein Rv3686c {Mycobacterium tuberculosis H37Rv (lab strain)}
3681Rv3687chypothetical protein Rv3687c {Mycobacterium tuberculosis H37Rv (lab strain)}
3682Rv3688chypothetical protein Rv3688c {Mycobacterium tuberculosis H37Rv (lab strain)}
3683Rv3689hypothetical protein Rv3689 {Mycobacterium tuberculosis H37Rv (lab strain)}
3684Rv3690hypothetical protein Rv3690 {Mycobacterium tuberculosis H37Rv (lab strain)}
3685Rv3691hypothetical protein Rv3691 {Mycobacterium tuberculosis H37Rv (lab strain)}
3686Rv3692, (MTV025.040), len: 358. Probable regulatory protein; similar to many, e.g. B. subtilis YEAC (320 aa);MTV014_8 M. tuberculosis putative regulatory protein; BBGIDBMOX_2B.burgdorferi gidB moxR genes (329 aa); AE001108_10Archaeoglobus fulgidus MoxR (324 aa) (moxR2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3687Rv3693hypothetical protein Rv3693 {Mycobacterium tuberculosis H37Rv (lab strain)}
3688Rv3694chypothetical protein Rv3694c {Mycobacterium tuberculosis H37Rv (lab strain)}
3689Rv3695hypothetical protein Rv3695 {Mycobacterium tuberculosis H37Rv (lab strain)}
3690Rv3696c, (MTV025.044c), glpK, len: 517. Probable glycerol kinase, (ATP:glycerol 3-phosphotransferase) similarto many, e.g. sp|P08859|GLPK_ECOLI GLYCEROL KINASE (501 aa)opt: 1740 z-score: 2108.9 E(): 0; 52.3% identity in 499 aaoverlap. Contains PS00933 FGGY famil (glpK) {Mycobacterium tuberculosis H37Rv (lab strain)}
3691Rv3697chypothetical protein Rv3697c {Mycobacterium tuberculosis H37Rv (lab strain)}
3692Rv3698hypothetical protein Rv3698 {Mycobacterium tuberculosis H37Rv (lab strain)}
3693Rv3699hypothetical protein Rv3699 {Mycobacterium tuberculosis H37Rv (lab strain)}
3694Rv3700chypothetical protein Rv3700c {Mycobacterium tuberculosis H37Rv (lab strain)}
3695Rv3701chypothetical protein Rv3701c {Mycobacterium tuberculosis H37Rv (lab strain)}
3696Rv3702chypothetical protein Rv3702c {Mycobacterium tuberculosis H37Rv (lab strain)}
3697Rv3703chypothetical protein Rv3703c {Mycobacterium tuberculosis H37Rv (lab strain)}
3698Rv3704c, (MTV025.052c), len: 432. gshA, similarity with gamma-glutamylcysteine synthetase from chloroplasts. Fasta scores: sp|P92951|P92951 GAMMA-GLUTAMYLCYSTEINE SYNTHETASE. (522 aa), opt: 395 z-score: 462.1 E(): 3.2e-18; 27.3%identity in 385 aa overlap. TBpars (gshA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3699Rv3705chypothetical protein Rv3705c {Mycobacterium tuberculosis H37Rv (lab strain)}
3700Rv3706chypothetical protein Rv3706c {Mycobacterium tuberculosis H37Rv (lab strain)}
3701Rv3707chypothetical protein Rv3707c {Mycobacterium tuberculosis H37Rv (lab strain)}
3702Rv3708c, (MTV025.056c), asd, len: 345. ASPARTATE SEMIALDEHYDE DEHYDROGENASE, identical to gp|U90239|MTU90239_3Mycobacterium tuberculosis aspart (345 aa), 100.0% identityin 345 aaoverlap. Also similar to MSASDASK_4 M.smegmatisasd, ask-alpha,; 80.3% identity in 34 (asd) {Mycobacterium tuberculosis H37Rv (lab strain)}
3703Rv3709c, (MTV025.057c), ask, len: 421. ASPARTOKINASE, highly similar to the aspartokinase of M. smegmatis : FASTA scores sp|P41403|AKAB_MYCSM ASPARTOKINASE ALPHA AND BETA SUBU (421aa) opt: 2423 z-score: 2839.1 E(): 0; 88.1% identity in 421aa overlap. Partially i (ask) {Mycobacterium tuberculosis H37Rv (lab strain)}
3704Rv3710, (MTV025.058), leuA, len: 644. Probable alpha-isopropyl malate synthase (leuA), almost identical to gp|U88526|MTU88526_1 M.tuberculosis (558 aa), FASTA scores: opt: 3611 z-score: 4007.8 E(): 0, 98.9% identity in 552 aa overlap. Contains PS00815 and PS008 (leuA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3705Rv3711c, (MTV025.059c), len: 329. dnaQ, similar toDNA polymerase III epsilon chain of several, e.g. sp|P03007|DP3E_ECOLI DNA POLYMERASE III, EPSILON CHAIN (243aa)FASTAscores: opt: 208 z-score: 262.0 E(): 4.4e-07; 28.4% identityin 169 aa overlap. Also similar to (dnaQ) {Mycobacterium tuberculosis H37Rv (lab strain)}
3706Rv3712hypothetical protein Rv3712 {Mycobacterium tuberculosis H37Rv (lab strain)}
3707Rv3713, (MTV025.061), len: 231. , cobQ2, partially similar to several cobyric acid synthases, e.g. gp|AE0008|AE000857_2 Methanobacterium thermoautotrophi (514 aa),opt:201 z-score: 236.5 E(): 1.2e-05. 32.9% identity in 170 aa overlap.Best FASTA scores with hypot (cobQ2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3708Rv3714chypothetical protein Rv3714c {Mycobacterium tuberculosis H37Rv (lab strain)}
3709Rv3715c, (MTV025.063c), recR, len: 203. Probable recombination protein recR, similar to many, e.g. sp|P24277|RECR_BACSU RECOMBINATION PROTEIN RECR (198 aa) FASTA scores: initn:644 init1: 438 opt: 696 z-score: 847.7 E(): 0;50.0% identity in 198 aa overlap. TBpars (recR) {Mycobacterium tuberculosis H37Rv (lab strain)}
3710Rv3716chypothetical protein Rv3716c {Mycobacterium tuberculosis H37Rv (lab strain)}
3711Rv3717hypothetical protein Rv3717 {Mycobacterium tuberculosis H37Rv (lab strain)}
3712Rv3718chypothetical protein Rv3718c {Mycobacterium tuberculosis H37Rv (lab strain)}
3713Rv3719hypothetical protein Rv3719 {Mycobacterium tuberculosis H37Rv (lab strain)}
3714Rv3720hypothetical protein Rv3720 {Mycobacterium tuberculosis H37Rv (lab strain)}
3715Rv3721c, (MTV025.069c), dnaZX, len: 578. Probable DNA POLYMERASE III SUBUNITS GAMMA (dnaZ) AND TAU (dnaX), similar to many, e.g. sp|P09122|DP3X_BACSU DNA POLYMERASE IIISUBUNITS GAMMA (563 aa), FASTA scores: opt: 841 z-score: 839.8 E(): 0, 30.8% identity in 510 a (dnaZX) {Mycobacterium tuberculosis H37Rv (lab strain)}
3716Rv3722chypothetical protein Rv3722c {Mycobacterium tuberculosis H37Rv (lab strain)}
3717Rv3723hypothetical protein Rv3723 {Mycobacterium tuberculosis H37Rv (lab strain)}
3718Rv3724hypothetical protein Rv3724 {Mycobacterium tuberculosis H37Rv (lab strain)}
3719Rv3725hypothetical protein Rv3725 {Mycobacterium tuberculosis H37Rv (lab strain)}
3720Rv3726hypothetical protein Rv3726 {Mycobacterium tuberculosis H37Rv (lab strain)}
3721Rv3727hypothetical protein Rv3727 {Mycobacterium tuberculosis H37Rv (lab strain)}
3722Rv3728hypothetical protein Rv3728 {Mycobacterium tuberculosis H37Rv (lab strain)}
3723Rv3729hypothetical protein Rv3729 {Mycobacterium tuberculosis H37Rv (lab strain)}
3724Rv3730chypothetical protein Rv3730c {Mycobacterium tuberculosis H37Rv (lab strain)}
3725Rv3731, (MTV025.079), len: 358. Possible DNA ligasesimilar to numerous archaebacterial and eukaryotic polynucleotide ligases, e.g. sp|O28549|O28549 DNA LIGASE, PUTATIVE.(313 aa) FASTA scores: opt: 313 z-score: 379.8 E(): 1.2e-13; 28.6% identity in 339 aa overla (ligC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3726Rv3732hypothetical protein Rv3732 {Mycobacterium tuberculosis H37Rv (lab strain)}
3727Rv3733chypothetical protein Rv3733c {Mycobacterium tuberculosis H37Rv (lab strain)}
3728Rv3734chypothetical protein Rv3734c {Mycobacterium tuberculosis H37Rv (lab strain)}
3729Rv3735hypothetical protein Rv3735 {Mycobacterium tuberculosis H37Rv (lab strain)}
3730Rv3736hypothetical protein Rv3736 {Mycobacterium tuberculosis H37Rv (lab strain)}
3731Rv3737hypothetical protein Rv3737 {Mycobacterium tuberculosis H37Rv (lab strain)}
3732Rv3738c, (MTV025.086c), len: 315. Member of M. tuberculosis PPEfamily, probaly a continuation of the upstreamORF MTV025.87c. At position 97470-72 a stop codon is presentwhich interrupts a possibly longer ORF, observed in relatedORFs MTV012_32 or MTCY21B4_4. The (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3733Rv3739c, (MTV025.087c), len: 77. Member of the M. tuberculosis PPE family, shows high homology with gp|AL0212|MTV012_32 and MTV012_36 Mycobacterium tuberculosis sequenc(434 aa); FASTA scores: opt: 398 z-score: 494.7 E(): 4.9e-20; 74.0% identity in 77 aa overlap. (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3734Rv3740chypothetical protein Rv3740c {Mycobacterium tuberculosis H37Rv (lab strain)}
3735Rv3741chypothetical protein Rv3741c {Mycobacterium tuberculosis H37Rv (lab strain)}
3736Rv3742chypothetical protein Rv3742c {Mycobacterium tuberculosis H37Rv (lab strain)}
3737Rv3743chypothetical protein Rv3743c {Mycobacterium tuberculosis H37Rv (lab strain)}
3738Rv3744hypothetical protein Rv3744 {Mycobacterium tuberculosis H37Rv (lab strain)}
3739Rv3745chypothetical protein Rv3745c {Mycobacterium tuberculosis H37Rv (lab strain)}
3740Rv3746c, (MTV025.094c), len: 111. Unknown, similar to M. tuberculosis PE-family proteins, but without the glycine-rich C-terminal part. FASTA scores: Rv3872 (MTV027.07)(99 aa, E(): 7.3e-12, 50.5% identity in 99 aa overlap), gp|Z77724|MTCY227_10 Mycobacterium tub (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3741Rv3747hypothetical protein Rv3747 {Mycobacterium tuberculosis H37Rv (lab strain)}
3742Rv3748hypothetical protein Rv3748 {Mycobacterium tuberculosis H37Rv (lab strain)}
3743Rv3749chypothetical protein Rv3749c {Mycobacterium tuberculosis H37Rv (lab strain)}
3744Rv3750chypothetical protein Rv3750c {Mycobacterium tuberculosis H37Rv (lab strain)}
3745Rv3751hypothetical protein Rv3751 {Mycobacterium tuberculosis H37Rv (lab strain)}
3746Rv3752chypothetical protein Rv3752c {Mycobacterium tuberculosis H37Rv (lab strain)}
3747Rv3753chypothetical protein Rv3753c {Mycobacterium tuberculosis H37Rv (lab strain)}
3748Rv3754, (MTV025.102), len: 301. Probable oxidoreductase, similar to many, e.g sp|P20692|TYRA_BACSU PREPHENATEDEHYDROGENASE (372 aa). FASTA scores: opt: 314 z-score: 384.3 E(): 6.8e-14; 27.8% identity in 263 aa overlap. Also similar to tyrC in ZMTYRC_1 Z.mobilis (tyrA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3749Rv3755chypothetical protein Rv3755c {Mycobacterium tuberculosis H37Rv (lab strain)}
3750Rv3756c, (MTV025.104c), len: 239. Probable transport system permease protein, similar to osmoprotection proteins (proW, proZ) involved in glycine betaine/L-proline transport in B. subtilis (Q45461 or PROZ_BACSU), A. fulgidus (AE001036_4) and E. coli (ECAE000352_ (proZ) {Mycobacterium tuberculosis H37Rv (lab strain)}
3751Rv3757c, (MTV025.105c), len: 225. Probable transport system permease protein, similar to osmoprotection proteins (proW, proZ) involved in glycine betaine/L-proline transport in B. subtilis (Q45461 or PROZ_BACSU), A. fulgidus (AE001036_4) and E. coli (ECAE000352_ (proW) {Mycobacterium tuberculosis H37Rv (lab strain)}
3752Rv3758c, (MTV025.106c), len: 376. Probable ABC transporter ATP-binding protein, similar to osmoprotection protein (proV) involved in glycine betaine/L-proline transportin B. subtilis (PROV_BACSU), A. fulgidus (AE001036_5) and E.coli (PROV_ECOLI). Also similar to (proV) {Mycobacterium tuberculosis H37Rv (lab strain)}
3753Rv3759c, (MTV025.107c), len: 315. Probable secretedprotein, similar to osmoprotection protein (proX) involvedin glycinebetaine/L-proline transport in B. subtilis (PROX_BACSU), and A. fulgidus (AE001036_6). Also similar to (opuBC), a choline binding protein precu (proX) {Mycobacterium tuberculosis H37Rv (lab strain)}
3754Rv3760hypothetical protein Rv3760 {Mycobacterium tuberculosis H37Rv (lab strain)}
3755Rv3761c, (MTV025.109c), len: 351. fadE36, has partial similarity (31.2% identity in 324 aa overlap) toCaenorhabditis elegans hypothetical protein, similar to acyl-CoA dehydrogenases and epoxide hydrolases CELK09H11_6 (974 aa). FASTA scores: opt: 530 z-score: 645 (fadE36) {Mycobacterium tuberculosis H37Rv (lab strain)}
3756Rv3762chypothetical protein Rv3762c {Mycobacterium tuberculosis H37Rv (lab strain)}
3757Rv3763, (MTV025.111), len: 159. 19 KD lipoprotein antigen precursor, almost identical (99.4% identity in 159 aa overlap)to gp|J03838|MSGANT19K_1 M.tuberculosis (Erdmann) 19 Kd antigen com (159 aa) and MB19KD_1 Mycobacterium bovis gene fora 20kD (159 aa). Also h (lpqH) {Mycobacterium tuberculosis H37Rv (lab strain)}
3758Rv3764chypothetical protein Rv3764c {Mycobacterium tuberculosis H37Rv (lab strain)}
3759Rv3765chypothetical protein Rv3765c {Mycobacterium tuberculosis H37Rv (lab strain)}
3760Rv3766hypothetical protein Rv3766 {Mycobacterium tuberculosis H37Rv (lab strain)}
3761Rv3767chypothetical protein Rv3767c {Mycobacterium tuberculosis H37Rv (lab strain)}
3762Rv3768hypothetical protein Rv3768 {Mycobacterium tuberculosis H37Rv (lab strain)}
3763Rv3769hypothetical protein Rv3769 {Mycobacterium tuberculosis H37Rv (lab strain)}
3764Rv3770chypothetical protein Rv3770c {Mycobacterium tuberculosis H37Rv (lab strain)}
3765Rv3771chypothetical protein Rv3771c {Mycobacterium tuberculosis H37Rv (lab strain)}
3766Rv3772, (MTCY13D12.06), hisC2, len: 353, Probable histidinol-phosphate aminotransferase, similar to eg HIS8_BACSU P17731 histidinol-phosphate aminotransferase (363 aa), fasta scores, opt: 555, E(): 8.9e-28, (30.7% identity in 355 aa overlap); contains PS00599 A (hisC2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3767Rv3773chypothetical protein Rv3773c {Mycobacterium tuberculosis H37Rv (lab strain)}
3768Rv3774, (MTCY13D12.08), len: 274. echA21, Probable enoyl-coA hydratase, similar to e.g. Rhizobium meliloti TR:Q52995 (EMBL:L39265) enoyl-CoA hydratase FADB1 (257 aa), fasta scores; opt: 279 z-score: 611.6 E(): 7.6e-27, 33.6% identity in 268 aa overlap (echA21) {Mycobacterium tuberculosis H37Rv (lab strain)}
3769Rv3775, (MTCY13D12.09), len: 415. Probable hydrolase, similar to e.g. Arthrobacter globiformis TR:Q44050 (EMBL:L22516) carboxylic-ester hydrolase (375 aa), fasta scores;opt: 346 z-score: 320.2 E(): 1.3e-10, 28.8% identity in 309aa overlap (lipE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3770Rv3776hypothetical protein Rv3776 {Mycobacterium tuberculosis H37Rv (lab strain)}
3771Rv3777hypothetical protein Rv3777 {Mycobacterium tuberculosis H37Rv (lab strain)}
3772Rv3778chypothetical protein Rv3778c {Mycobacterium tuberculosis H37Rv (lab strain)}
3773Rv3779hypothetical protein Rv3779 {Mycobacterium tuberculosis H37Rv (lab strain)}
3774Rv3780hypothetical protein Rv3780 {Mycobacterium tuberculosis H37Rv (lab strain)}
3775Rv3781hypothetical protein Rv3781 {Mycobacterium tuberculosis H37Rv (lab strain)}
3776Rv3782, (MTCY13D12.16), len: 304. Unknown, some similarity to Methanobacterium thermoautotrophicum gene described as TR:O26448 RHAMNOSYL TRANSFERASE (313 aa), fasta scores; opt: 177 z-score: 335.3 E(): 1.9e-11, 27.9% identity in333 aa overlap, but no similarity (rfbE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3777Rv3783hypothetical protein Rv3783 {Mycobacterium tuberculosis H37Rv (lab strain)}
3778Rv3784, (MTCY13D12.18), len: 326. epiB, Possible dtdp-glucose 4,6-dehydratase, similar to e.g. RFFG_ECOLI P27830 dtdp-glucose 4,6-dehydratase (355 aa), fasta scores; opt: 401z-score: 629.6 E(): 7.5e-28, 31.3% identity in 348 aa overlap (epiB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3779Rv3785hypothetical protein Rv3785 {Mycobacterium tuberculosis H37Rv (lab strain)}
3780Rv3786chypothetical protein Rv3786c {Mycobacterium tuberculosis H37Rv (lab strain)}
3781Rv3787chypothetical protein Rv3787c {Mycobacterium tuberculosis H37Rv (lab strain)}
3782Rv3788hypothetical protein Rv3788 {Mycobacterium tuberculosis H37Rv (lab strain)}
3783Rv3789hypothetical protein Rv3789 {Mycobacterium tuberculosis H37Rv (lab strain)}
3784Rv3790hypothetical protein Rv3790 {Mycobacterium tuberculosis H37Rv (lab strain)}
3785Rv3791hypothetical protein Rv3791 {Mycobacterium tuberculosis H37Rv (lab strain)}
3786Rv3792hypothetical protein Rv3792 {Mycobacterium tuberculosis H37Rv (lab strain)}
3787Rv3793, (MTCY13D12.27), embC, len: 1094. Probable arabinosyltransferase, highly similar to fragment sequence of MYCOBACTERIUM SMEGMATIS, G1197631 embC (257 aa), fasta scores, opt: 1431, E(): 0, (78.3% identity in 258 aa overlap), similar to G1197633 embB, (1066 (embC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3788Rv3794, (MTCY13D12.28), embA, len: 1094. Probable arabinosyltransferase, highly similar to MYCOBACTERIUM SMEGMATIS, G1197632 embA (1078 aa), fasta scores, opt: 4069, E(): 0, (67.4% identity in 1085 aa overlap) (embA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3789Rv3795, (MTCY13D12.29), embB, len: 1098, Probable arabinosyltransferase, highly similar to G1197633 embB, (1066 aa), fasta scores, opt: 4144, E(): 0, (68.2% identity in1091 aa overlap) (embB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3790Rv3796, (MTV026.01-MTCY13D12.30), atsH, len: 375. Possible hydrolase, similar to e.g. ARS_ALTCA P28607 arylsulfatase precursor (ec 3.1.6.1) (328 aa), fasta scores; opt:166 z-score: 254.1 E(): 6.2e-07, 24.8% identity in 331 aa overlap (atsH) {Mycobacterium tuberculosis H37Rv (lab strain)}
3791Rv3797, (MTV026.02), len: 593. fadE35, Probable acyl Co-A dehydrogenase similar to E. coli AidB protein, gp|L20915|ECOAIDB_3 E. coli (aidB) gene, comp (541 aa): FASTA scores: opt: 455 z-score: 561.5 E(): 9.2e-24. 31.1% identity in 514 aa overlap.Also similar to (fadE35) {Mycobacterium tuberculosis H37Rv (lab strain)}
3792Rv3798hypothetical protein Rv3798 {Mycobacterium tuberculosis H37Rv (lab strain)}
3793Rv3799c, (MTV026.04c), accD4, len: 517. Probable Propionyl-CoA carboxylase; Beta chain, similar to many, e.g. sp|P53003|PCCB_SACER PROPIONYL-COA CARBOXYLASE BETA CH (546aa), FASTA scores: opt: 1549 z-score: 1841.5 E(): 0; 50.7%identity in 519 aa overlap, Also si (accD4) {Mycobacterium tuberculosis H37Rv (lab strain)}
3794Rv3800c, (MTV026.05c), len: 1733. Probable polyketide synthase, similar to many. e.g. gp|M63676|SERERYAA_1 S.erythraea first ORF of eryA gene, involved in complex polyketide formation in erythromycin biosynthesis. FASTA scores: opt: 1329 z-score: 1411.0 E(): 0, (pks13) {Mycobacterium tuberculosis H37Rv (lab strain)}
3795Rv3801c, (MTV026.06c), len: 637. fadD32, polyketide synthase, similar to gp|Z97188|MTCY409_4 M. tuberculosiscosmid (584 aa). FASTA scores: opt: 1094 z-score: 1262.3 E(): 0, 36.8% identity in 585 aa overlap. Also similar to manyother mycobacterial hypothetical pr (fadD32) {Mycobacterium tuberculosis H37Rv (lab strain)}
3796Rv3802chypothetical protein Rv3802c {Mycobacterium tuberculosis H37Rv (lab strain)}
3797Rv3803c, (MTV026.08c), fbpC1, len: 299. MPB51 PRECURSOR of the 85-C antigen, mycolyltransferase identical to gp|AJ0021|MTAJ2150_1 M. tuberculosis H37Rv,(299 aa), FASTA scores: opt: 2088 z-score: 2234.4 E(): 0, 99.7% identity in 299 aa overlap, and gp|D26486|MSG3 (fbpC1) {Mycobacterium tuberculosis H37Rv (lab strain)}
3798Rv3804c, (MTV026.09c), fbpA, len: 338. 32 kDa antigen protein 85-A precursor, mycolyltransferase, FASTA scores: gp|M27016|MSG32KDA_1 M. tuberculosis 32 kDa (338 aa), opt: 2341 z-score: 2660.8 E(): 0, 100.0% identity in 338 aa overlap, almost identical to 85-A pr (fbpA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3799Rv3805chypothetical protein Rv3805c {Mycobacterium tuberculosis H37Rv (lab strain)}
3800Rv3806chypothetical protein Rv3806c {Mycobacterium tuberculosis H37Rv (lab strain)}
3801Rv3807chypothetical protein Rv3807c {Mycobacterium tuberculosis H37Rv (lab strain)}
3802Rv3808chypothetical protein Rv3808c {Mycobacterium tuberculosis H37Rv (lab strain)}
3803Rv3809c, (MTV026.14), glf, len: 399. UDP-galactopyranose mutase, Identical to previously sequenced gene. FASTAscores: gp|U96128|MTU96128_1 Mycobacterium tuberculosis UDP-ga (399 aa) opt: 2709 z-score: 3166.0 E(): 0, 100.0% identity in 399 aa overlap (glf) {Mycobacterium tuberculosis H37Rv (lab strain)}
3804Rv3810, (MTV026.15), pirg, len: 284. Cell surface protein precursor, almost identical to gp|L38851|MSGPIRG_1 M. tuberculosis cell surface (284 aa)opt: 1850 z-score: 1342.3 E(): 0,99.3% identity in 284 aa overlap and gp|A49359|A49359_1 Sequence 40 from Patent WO (pirG) {Mycobacterium tuberculosis H37Rv (lab strain)}
3805Rv3811, (MTV026.16), len: 539. ,csp, some short similarity to gp|X66078|CGCOP1G_1 C. glutamicum cop1 gene forPS1. (657 aa), FASTA scores: opt: 250 z-score: 244.4 E():4.2e-06 39.4% identity in 109 aa overlap, Contains PS00687Aldehydedehydrogenases glutamic acid (csp) {Mycobacterium tuberculosis H37Rv (lab strain)}
3806Rv3812, (MTV026.17,MTCY409.18c), len: 540. Glycine rich hypothetical protein belonging to PGRS (PE) family, similar to many e.g. YW36_MYCTU Q10873 hypothetical 53.7 kd protein cy39.36c (558 aa), fasta scores; opt: 327 z-score: 458.5 E(): 2.5e-18, 28.5% identity (PE_PGRS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3807Rv3813chypothetical protein Rv3813c {Mycobacterium tuberculosis H37Rv (lab strain)}
3808Rv3814chypothetical protein Rv3814c {Mycobacterium tuberculosis H37Rv (lab strain)}
3809Rv3815chypothetical protein Rv3815c {Mycobacterium tuberculosis H37Rv (lab strain)}
3810Rv3816chypothetical protein Rv3816c {Mycobacterium tuberculosis H37Rv (lab strain)}
3811Rv3817hypothetical protein Rv3817 {Mycobacterium tuberculosis H37Rv (lab strain)}
3812Rv3818hypothetical protein Rv3818 {Mycobacterium tuberculosis H37Rv (lab strain)}
3813Rv3819hypothetical protein Rv3819 {Mycobacterium tuberculosis H37Rv (lab strain)}
3814Rv3820c, (MTCY409.10), len: 468. Unknown, similar to M. leprae hypothetical gene TR:Q49618 (sus) from cosmid B1170 (471 aa), fasta scores; opt: 1660 z-score: 2129.4 E():0, 53.9% identity in 456 aa overlap; weakly similar to partof TR:Q54297 polyketide synthase f (papA2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3815Rv3821hypothetical protein Rv3821 {Mycobacterium tuberculosis H37Rv (lab strain)}
3816Rv3822hypothetical protein Rv3822 {Mycobacterium tuberculosis H37Rv (lab strain)}
3817Rv3823c, (MTCY409.07), len: 1089. Unknown, possiblemembrane protein, similar to several Mycobacterial hypothetical proteins eg. TR:Q50585 hypothetical 122.4 KD protein MTCY19G5.06(1146 aa), fasta scores; opt: 2427 z-score: 3606.9 E():0, 50.0% identity in 1051 aa (mmpL8) {Mycobacterium tuberculosis H37Rv (lab strain)}
3818Rv3824c, (MTCY409.06), len: 511. Unknown, similar to part of Q09164 cyclosporin synthetase (CYSYN) from Tolypocladium niveum (15281 aa), fasta scores; opt: 238 z-score: 216.5 E(): 4.8e-05, 21.7% identity in 369 aa overlap. Contains PS00453FKBP-type peptidyl-prol (papA1) {Mycobacterium tuberculosis H37Rv (lab strain)}
3819Rv3825c, (MTCY409.05), len: 2126. Probable polyketide synthase, highly similar to MCAS_MYCBO Q02251 mycocerosic acid synthase from Mycobacterium bovis (2110 aa), fasta scores; opt: 3495 z-score: 8755.7 E(): 0, 61.6% identity in 2130 aa overlap. Contains PS00606 (pks2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3820Rv3826, (MTCY409.04c), len: 584.fadD23, Possible polyketide synthase, similar to eg. YMA2_MYCBO Q02278 hypothetical 32.3 kd protein upstream of mycocerosic acid synthase (298 aa), fasta scores opt: 1180 z-score: 1269.6 E(): 0, 60.8% identity in 288 aa overlap; (fadD23) {Mycobacterium tuberculosis H37Rv (lab strain)}
3821Rv3827chypothetical protein Rv3827c {Mycobacterium tuberculosis H37Rv (lab strain)}
3822Rv3828chypothetical protein Rv3828c {Mycobacterium tuberculosis H37Rv (lab strain)}
3823Rv3829chypothetical protein Rv3829c {Mycobacterium tuberculosis H37Rv (lab strain)}
3824Rv3830chypothetical protein Rv3830c {Mycobacterium tuberculosis H37Rv (lab strain)}
3825Rv3831hypothetical protein Rv3831 {Mycobacterium tuberculosis H37Rv (lab strain)}
3826Rv3832chypothetical protein Rv3832c {Mycobacterium tuberculosis H37Rv (lab strain)}
3827Rv3833hypothetical protein Rv3833 {Mycobacterium tuberculosis H37Rv (lab strain)}
3828Rv3834c, (MTCY01A6.35), len: 419. Seryl-trna synthetase, similar eg to SYS_BACSU P37464 (425 aa), fasta scores, opt: 1015, E(): 0, (39.3% identity in 425 aa overlap); contains PS00179 Aminoacyl-transfer RNA synthetases class-II signature 1 (serS) {Mycobacterium tuberculosis H37Rv (lab strain)}
3829Rv3835hypothetical protein Rv3835 {Mycobacterium tuberculosis H37Rv (lab strain)}
3830Rv3836hypothetical protein Rv3836 {Mycobacterium tuberculosis H37Rv (lab strain)}
3831Rv3837chypothetical protein Rv3837c {Mycobacterium tuberculosis H37Rv (lab strain)}
3832Rv3838c, (MTCY01A6.31), len: 321. Possible prephenate dehydratase, similar to PHEA_CORGL P10341 prephenate dehydratase (315 aa), fasta scores, opt: 843, E(): 0, (45.8% identity in 308 aa overlap); contains PS00858 Prephenate dehydratase signature 2 (pheA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3833Rv3839hypothetical protein Rv3839 {Mycobacterium tuberculosis H37Rv (lab strain)}
3834Rv3840hypothetical protein Rv3840 {Mycobacterium tuberculosis H37Rv (lab strain)}
3835Rv3841, (MTCY01A6.28c), len: 181. bfrB, Similar to ferritin e.g. FRH2_SCHMA P25320 ferritin-2 heavy chain (172aa), fasta scores, opt: 199, E(): 4.9e-07, (29.7% identityin 145 aa overlap) (bfrB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3836Rv3842c, (MTCY01A6.27), len: 274. glpQ1, Similar toe.g. GLPQ_BACSU P37965 glycerophosphoryl diester phosphodiesterase (293 aa), fasta scores, opt: 405, E(): 3.1e-21 (31.3% identity in 249 aa overlap) (glpQ1) {Mycobacterium tuberculosis H37Rv (lab strain)}
3837Rv3843chypothetical protein Rv3843c {Mycobacterium tuberculosis H37Rv (lab strain)}
3838Rv3844hypothetical protein Rv3844 {Mycobacterium tuberculosis H37Rv (lab strain)}
3839Rv3845hypothetical protein Rv3845 {Mycobacterium tuberculosis H37Rv (lab strain)}
3840Rv3846, (MTCY01A6.22c), sodA, len: 207. Identical to SODF_MYCTU P17670 superoxide dismutase (fe) (207 aa), PS00088 Manganese and iron superoxide dismutases signature (sodA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3841Rv3847hypothetical protein Rv3847 {Mycobacterium tuberculosis H37Rv (lab strain)}
3842Rv3848hypothetical protein Rv3848 {Mycobacterium tuberculosis H37Rv (lab strain)}
3843Rv3849hypothetical protein Rv3849 {Mycobacterium tuberculosis H37Rv (lab strain)}
3844Rv3850hypothetical protein Rv3850 {Mycobacterium tuberculosis H37Rv (lab strain)}
3845Rv3851hypothetical protein Rv3851 {Mycobacterium tuberculosis H37Rv (lab strain)}
3846Rv3852, (MTCY01A6.16c), len: 134. hns, Similar to histones e.g. H1C6_TRYCR P40269 histone h1.c6/h1.c9. trypanosoma cruz (87 aa), fasta scores; opt: 151 z-score: 191.4 E(): 0.0019, 38.6% identity in 83 aa overlap (hns) {Mycobacterium tuberculosis H37Rv (lab strain)}
3847Rv3853, (MTCY01A6.15c), menG, len: 157. Probable s-adenosylmethionine:2-demethylmenaquinone methyltransferase,highly similar to MENG_ECOLI P32165 s-adenosylmethionine:2-demethylmenaquinone biosynthesis protein menG (161 aa), fasta scores, opt: 428, E(): 1.3e-21 (menG) {Mycobacterium tuberculosis H37Rv (lab strain)}
3848Rv3854chypothetical protein Rv3854c {Mycobacterium tuberculosis H37Rv (lab strain)}
3849Rv3855hypothetical protein Rv3855 {Mycobacterium tuberculosis H37Rv (lab strain)}
3850Rv3856chypothetical protein Rv3856c {Mycobacterium tuberculosis H37Rv (lab strain)}
3851Rv3857chypothetical protein Rv3857c {Mycobacterium tuberculosis H37Rv (lab strain)}
3852Rv3858c, (MTCY01A6.10), gltD, len: 488. Probable small subunit of NADH-dependent glutamate synthase, simialr to many e.g. GLTD_ECOLI P09832 glutamate synthase (nadph) small chai (471 aa), fasta scores; opt: 889 z-score: 730.2 E(): 0, 37.4% identity in 473 aa ove (gltD) {Mycobacterium tuberculosis H37Rv (lab strain)}
3853Rv3859c, (MTCY01A6.09), gltB, len: 1527. Probable ferredoxin-dependent glutamate synthase, similar to e.g. GLTB_SYNY3 P55037 ferredoxin-dependent glutamate synthase (1550aa), fasta scores, opt: 3685, E(): 0, (57.1% identity in 1540 aa overlap) (gltB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3854Rv3860hypothetical protein Rv3860 {Mycobacterium tuberculosis H37Rv (lab strain)}
3855Rv3861hypothetical protein Rv3861 {Mycobacterium tuberculosis H37Rv (lab strain)}
3856Rv3862chypothetical protein Rv3862c {Mycobacterium tuberculosis H37Rv (lab strain)}
3857Rv3863hypothetical protein Rv3863 {Mycobacterium tuberculosis H37Rv (lab strain)}
3858Rv3864hypothetical protein Rv3864 {Mycobacterium tuberculosis H37Rv (lab strain)}
3859Rv3865hypothetical protein Rv3865 {Mycobacterium tuberculosis H37Rv (lab strain)}
3860Rv3866hypothetical protein Rv3866 {Mycobacterium tuberculosis H37Rv (lab strain)}
3861Rv3867hypothetical protein Rv3867 {Mycobacterium tuberculosis H37Rv (lab strain)}
3862Rv3868hypothetical protein Rv3868 {Mycobacterium tuberculosis H37Rv (lab strain)}
3863Rv3869hypothetical protein Rv3869 {Mycobacterium tuberculosis H37Rv (lab strain)}
3864Rv3870hypothetical protein Rv3870 {Mycobacterium tuberculosis H37Rv (lab strain)}
3865Rv3871hypothetical protein Rv3871 {Mycobacterium tuberculosis H37Rv (lab strain)}
3866Rv3872, (MTV027.07), len: 99. Some similarity to M.tuberculosis conserved PE family proteins, e.g. MTV035.13 (102 aa) E(): 0.00017, 32.4% identity in 71 aa overlap (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3867Rv3873, (MTV027.08), len: 368. Member of M. tuberculosis PPE family, similar to many e.g. TR:O33205 (EMBL:Z98268) MTCI125.28C (394 aa), fasta scores; opt: 446, E(): 5.9e-14, 31.5%identity in 349 aa overlap (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3868Rv3874hypothetical protein Rv3874 {Mycobacterium tuberculosis H37Rv (lab strain)}
3869Rv3875, (MTV027.10), esat6, len: 95. Identical to early secretory antigen target esta6 from M. tuberculosis (Erdman) andM. bovis TR:Q57165 (EMBL:X79562) ESAT6 (95 aa). Also similar to homologs from M. leprae e.g. TR:Q50206 (EMBL:X90946) L-ESAT. Contains probabl (esat6) {Mycobacterium tuberculosis H37Rv (lab strain)}
3870Rv3876hypothetical protein Rv3876 {Mycobacterium tuberculosis H37Rv (lab strain)}
3871Rv3877hypothetical protein Rv3877 {Mycobacterium tuberculosis H37Rv (lab strain)}
3872Rv3878hypothetical protein Rv3878 {Mycobacterium tuberculosis H37Rv (lab strain)}
3873Rv3879chypothetical protein Rv3879c {Mycobacterium tuberculosis H37Rv (lab strain)}
3874Rv3880chypothetical protein Rv3880c {Mycobacterium tuberculosis H37Rv (lab strain)}
3875Rv3881chypothetical protein Rv3881c {Mycobacterium tuberculosis H37Rv (lab strain)}
3876Rv3882chypothetical protein Rv3882c {Mycobacterium tuberculosis H37Rv (lab strain)}
3877Rv3883chypothetical protein Rv3883c {Mycobacterium tuberculosis H37Rv (lab strain)}
3878Rv3884chypothetical protein Rv3884c {Mycobacterium tuberculosis H37Rv (lab strain)}
3879Rv3885chypothetical protein Rv3885c {Mycobacterium tuberculosis H37Rv (lab strain)}
3880Rv3886chypothetical protein Rv3886c {Mycobacterium tuberculosis H37Rv (lab strain)}
3881Rv3887chypothetical protein Rv3887c {Mycobacterium tuberculosis H37Rv (lab strain)}
3882Rv3888chypothetical protein Rv3888c {Mycobacterium tuberculosis H37Rv (lab strain)}
3883Rv3889chypothetical protein Rv3889c {Mycobacterium tuberculosis H37Rv (lab strain)}
3884Rv3890chypothetical protein Rv3890c {Mycobacterium tuberculosis H37Rv (lab strain)}
3885Rv3891chypothetical protein Rv3891c {Mycobacterium tuberculosis H37Rv (lab strain)}
3886Rv3892c, (MTCY15F10.20), len: 399. Member of the M.tuberculosis PPE family of conserved proteins, similar to many e.g. MTV049.23 (423 aa) E(): 6.1e-06, 28.7% identity in401 aa overlap (PPE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3887Rv3893c, (MTCY15F10.19), len: 77. Member of the M.tuberculosis PE family of conserved proteins similar to e.g.MTV035.13 (102 aa) E(): 2.5e-05, 35.6% identity in 73 aa overlap (PE) {Mycobacterium tuberculosis H37Rv (lab strain)}
3888Rv3894chypothetical protein Rv3894c {Mycobacterium tuberculosis H37Rv (lab strain)}
3889Rv3895chypothetical protein Rv3895c {Mycobacterium tuberculosis H37Rv (lab strain)}
3890Rv3896chypothetical protein Rv3896c {Mycobacterium tuberculosis H37Rv (lab strain)}
3891Rv3897chypothetical protein Rv3897c {Mycobacterium tuberculosis H37Rv (lab strain)}
3892Rv3898chypothetical protein Rv3898c {Mycobacterium tuberculosis H37Rv (lab strain)}
3893Rv3899chypothetical protein Rv3899c {Mycobacterium tuberculosis H37Rv (lab strain)}
3894Rv3900chypothetical protein Rv3900c {Mycobacterium tuberculosis H37Rv (lab strain)}
3895Rv3901chypothetical protein Rv3901c {Mycobacterium tuberculosis H37Rv (lab strain)}
3896Rv3902chypothetical protein Rv3902c {Mycobacterium tuberculosis H37Rv (lab strain)}
3897Rv3903chypothetical protein Rv3903c {Mycobacterium tuberculosis H37Rv (lab strain)}
3898Rv3904chypothetical protein Rv3904c {Mycobacterium tuberculosis H37Rv (lab strain)}
3899Rv3905chypothetical protein Rv3905c {Mycobacterium tuberculosis H37Rv (lab strain)}
3900Rv3906chypothetical protein Rv3906c {Mycobacterium tuberculosis H37Rv (lab strain)}
3901Rv3907c, (MTCY15F10.04), pcnA, len: 480. Function: Probable polynucleotide polymerase; contains ATP/GTP-binding site motif A (P-loop; PS00017) and EF-hand calcium-binding domain (PS00018), and probably less significantly G-protein coupled receptors signature (PS (pcnA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3902Rv3908hypothetical protein Rv3908 {Mycobacterium tuberculosis H37Rv (lab strain)}
3903Rv3909hypothetical protein Rv3909 {Mycobacterium tuberculosis H37Rv (lab strain)}
3904Rv3910hypothetical protein Rv3910 {Mycobacterium tuberculosis H37Rv (lab strain)}
3905Rv3911, (MTV028.02), len: 222. Possible sigma factor, weakly similar to many eg. M.tuberculosis TR:O06289 (EMBL:U87242) SIGE (257 aa), fasta scores; opt: 193 z-score: 237.8 E(): 4.8e-06, 33.1% identity in 163 aa overlap. Also similar to M. tuberculosis MTCI61.0 (sigM) {Mycobacterium tuberculosis H37Rv (lab strain)}
3906Rv3912hypothetical protein Rv3912 {Mycobacterium tuberculosis H37Rv (lab strain)}
3907Rv3913, (MTV028.04), trxB, len: 335. Thioredoxin reductase, almost identical to TRXB_MYCTU P52214 thioredoxin reductase (ec 1.6.4.5) and highly similar to many eg. TRXB_ECOLI P09625 thioredoxin reductase (ec 1.6.4.5) (320 aa), fasta scores; opt: 948 z-score: 11 (trxB2) {Mycobacterium tuberculosis H37Rv (lab strain)}
3908Rv3914, (MTV028.05), trxC, len: 116. Thioredoxin, identical to THIO_MYCTU P52229 thioredoxin (116 aa) and highly similar to may eg. THIO_ECOLI P00274 thioredoxin (108 aa), fastascores; opt: 364 z-score: 655.3 E(): 2.6e-29, 54.5%identityin 101 aa overlap. Contai (trxC) {Mycobacterium tuberculosis H37Rv (lab strain)}
3909Rv3915, (MTV028.06), len: 406.cwlM, Probable hydrolase, similar to parts of BACILLUS LICHENIFORMIS CWLM_BACLIP37134 n-acetylmuramoyl-l-alanine amidase cwlM (253 aa), fasta scortes;opt:151 z-score: 281.1 E(): 1.8e-08, 27.7% identity in 191 aa overlap and CWLL_BA (cwlM) {Mycobacterium tuberculosis H37Rv (lab strain)}
3910Rv3916chypothetical protein Rv3916c {Mycobacterium tuberculosis H37Rv (lab strain)}
3911Rv3917c,(MTV028.08c), len: 344. Unknown, similar toTR:O05190 CHROMOSOME PARTITIONING PROTEIN PARB from CAULOBACTER CRESCENTUS (293 aa), fasta scores; opt: 564 z-score: 784.2 E():0, 38.6% identity in 308 aa overlap; and to SP0J_BACSU P26497 stage 0 sporulation pr (parA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3912Rv3918c, (MTV028.09c), len: 347. Unknown, similar to TR:O05189(EMBL:U87804) CHROMOSOME PARTITIONING PROTEIN PARA from CAULOBACTER CRESCENTUS (266 aa), fasta scores; opt:787 z-score: 990.9 E(): 0, 50.6% identity in 261 aa overlapand to SOJ_BACSU P37522 soj protei (parB) {Mycobacterium tuberculosis H37Rv (lab strain)}
3913Rv3919c, (MTV028.10c), len: 224. gid, similar to GIDB_ECOLI P17113 glucose inhibited division protein b. (207aa),fasta scores; opt: 287 z-score: 274.7 E(): 4.2e-08, 34.8% identity in 138 aa overlap, and to other gidBs. Contains PS00539 Pyrokinins signature (gid) {Mycobacterium tuberculosis H37Rv (lab strain)}
3914Rv3920chypothetical protein Rv3920c {Mycobacterium tuberculosis H37Rv (lab strain)}
3915Rv3921chypothetical protein Rv3921c {Mycobacterium tuberculosis H37Rv (lab strain)}
3916Rv3922chypothetical protein Rv3922c {Mycobacterium tuberculosis H37Rv (lab strain)}
3917Rv3923c, (MTV028.14c), rnpA, len: 375. Ribonucleasep protein component, identical to, but longer than, TR:Q50789 EMBL:X92504 RNPA from M. tuberculosis (116 aa), also similar to others eg. RNPA_STRCO P48206 ribonuclease p proteincomponent(123 aa), fasta scores; o (rnpA) {Mycobacterium tuberculosis H37Rv (lab strain)}
3918Rv3924c, (MTV028.15), rpmH, len: 47. 50s ribosomal protein l34, identical to RL34_MYCTU P52829 (47 aa) and hyighly similar to others eg. RL34_ECOLI P02437 50s ribosomal protein l34 (46 aa), fasta scores opt: 159 z-score: 295.7 E(): 2.9e-09, 54.8% identity in 42 (rpmH) {Mycobacterium tuberculosis H37Rv (lab strain)}