MycoBiomDB – Record Details (MyCo_7189)

Biomarker Record Details

Database ID: MyCo_7189
DB IDMyCo_7189
TitleCOVID-19 Impairs Immune Response to Candida albicans
Year2021
PMID33717195
Fungal Diseases involvedCandida albicans infection
Associated Medical ConditionCOVID-19
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementInformed consent was obtained from next of kins or carers of all patients and from healthy volunteers, respectively. This study was performed after obtaining the LMU Medical Faculty ethics committee approval (#20-271 and #19-778) and conducted in agreement with the ethical norms and standards of the Declaration of Helsinki.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceBlood
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NamePD-1+ CD4+
Biomarker Full NamePD-1+ CD4+
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationGermany
CohortPatients with pneumonia resulting from confirmed SARS-CoV-2 infection were included in this study upon admittance to the ICU, when they required intubation and ventilation.
Cohort No.11
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueImmunological assay
Analysis MethodWhole Blood Incubation Assay and Immune Phenotyping
ELISA kitsNone
Assay DataNone
Validation Techniques usedWhole Blood Incubation Assay and Immune Phenotyping
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone