MycoBiomDB – Record Details (MyCo_7137)

Biomarker Record Details

Database ID: MyCo_7137
DB IDMyCo_7137
TitleThe Role of Autophagy in the Innate Immune Response to Fungal Keratitis Caused by Aspergillus fumigatus Infection
Year2020
PMID32084267
Fungal Diseases involvedFungal keratitis
Associated Medical ConditionNone
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementPatients consented to the management of samples, and the experiment was approved by the Institutional Research Ethics Committee at the Affiliated Hospital of Qingdao University.
Site of InfectionEye
Opportunistic invasiveNone
Sample typeBiopsy
Sample sourceCorneal samples
Host GroupAnimal
Host Common nameMice
Host Scientific nameMus musculus
Biomarker NameLAMP-1
Biomarker Full NameLAMP-1
Biomarker TypeDiagnostic
BiomoleculeGene
Geographical LocationChina
CohortSpecificpathogen-freeC57BL/6mice(female,8weeks)were purchased from Changzhou Cavens Laboratory Animal Co., Ltd. (Jiangsu, China). The animals were treated according to the Statement for the Use of Animals in Ophthalmic and Vision Research made by the ARVO.
Cohort No.None
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAnalytic
Analysis MethodWestern Blot Analysis
ELISA kitsNone
Assay DataNone
Validation Techniques usedWestern Blot Analysis, qRT-PCR
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone