MycoBiomDB – Record Details (MyCo_7098)

Biomarker Record Details

Database ID: MyCo_7098
DB IDMyCo_7098
Titleβ-1,3-d-Glucan and Galactomannan as Biomarkers for the Detection of Invasive Geotrichum and Magnusiomyces Infections: a Retrospective Evaluation
Year2021
PMID34669454
Fungal Diseases involvedInvasive Geotrichum
Associated Medical ConditionNone
GenusGeotrichum
Speciessilvicola
OrganismGeotrichum silvicola
Ethical StatementThis retrospective study was reviewed and approved by the ethics committee of our university hospital (Ethikkommission der Medizinischen Fakultät der LMU Munich) and conducted in accordance with the Declaration of Helsinki.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameBDG
Biomarker Full Name1-3-beta-D-Glucan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationGermany
CohortThis retrospective analysis was performed at the Max von Pettenkofer Institute of Hygiene and Medical Microbiology that hosts the central microbiology laboratory for the University Hospital of Ludwig Maximilians University (LMU) Munich, a 2,000-bed university medical center in Munich, Germany. In an 11-year observation period in a university hospital, 31 and 7 cases of invasive M. capitatus and Geotrichum spp. infections could be identi ed, respectively.
Cohort No.38
Age Group59
P ValueNone
Sensitivity0.65
Specificity0.96
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAssay
Analysis MethodWako BDG assay
ELISA kitsPlatelia™ Aspergillus Ag Kit (BioRad, Hercules, CA, USA)
Assay DataWako BDG test Assay
Validation Techniques usedFDA Approved -Platelia Aspergillus Ag ELISA, Wako BDG assay
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone