| DB ID | MyCo_7098 |
| Title | β-1,3-d-Glucan and Galactomannan as Biomarkers for the Detection of Invasive Geotrichum and Magnusiomyces Infections: a Retrospective Evaluation |
| Year | 2021 |
| PMID | 34669454 |
| Fungal Diseases involved | Invasive Geotrichum |
| Associated Medical Condition | None |
| Genus | Geotrichum |
| Species | silvicola |
| Organism | Geotrichum silvicola |
| Ethical Statement | This retrospective study was reviewed and approved by the ethics committee of our university hospital (Ethikkommission der Medizinischen Fakultät der LMU Munich) and conducted in accordance with the Declaration of Helsinki. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | BDG |
| Biomarker Full Name | 1-3-beta-D-Glucan |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Germany |
| Cohort | This retrospective analysis was performed at the Max von Pettenkofer Institute of Hygiene and Medical Microbiology that hosts the central microbiology laboratory for the University Hospital of Ludwig Maximilians University (LMU) Munich, a 2,000-bed university medical center in Munich, Germany. In an 11-year observation period in a university hospital, 31 and 7 cases of invasive M. capitatus and Geotrichum spp. infections could be identi ed, respectively. |
| Cohort No. | 38 |
| Age Group | 59 |
| P Value | None |
| Sensitivity | 0.65 |
| Specificity | 0.96 |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Assay |
| Analysis Method | Wako BDG assay |
| ELISA kits | Platelia™ Aspergillus Ag Kit (BioRad, Hercules, CA, USA) |
| Assay Data | Wako BDG test Assay |
| Validation Techniques used | FDA Approved -Platelia Aspergillus Ag ELISA, Wako BDG assay |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |