MycoBiomDB – Record Details (MyCo_7089)

Biomarker Record Details

Database ID: MyCo_7089
DB IDMyCo_7089
TitleSerologic biomarkers in Candida and Aspergillus infections of the central nervous system: A comparison of galactomannan, mannan and β-1,3-D-gucan testing from serum and cerebrospinal fluid
Year2022
PMID35506957
Fungal Diseases involvedAspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesfumigatus
OrganismAspergillus fumigatus
Ethical StatementNone
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceSerum
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameBDG
Biomarker Full Name1-3-beta-D-Glucan
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationGermany
CohortSerum and cerebrospinal fluid (CSF; 10) samples of 19 patients, whose CNS specimens yielded growth of Aspergillus or Candida, were analysed for different biomarkers for fungal infection.
Cohort No.19
Age GroupNone
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAssay
Analysis MethodWako BDG assay
ELISA kitsWako β-Glucan Test Kit (FUJIFILM Wako Chemicals Europe) , ELISA Kit- Platelia Aspergillus (Platelia Aspergillus EIA; Bio-Rad, Marnes la Coquette, France)
Assay DataNone
Validation Techniques usedWako BDG assay
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone