MycoBiomDB – Record Details (MyCo_7085)

Biomarker Record Details

Database ID: MyCo_7085
DB IDMyCo_7085
TitleUsefulness of procalcitonin in differentiating Candida and bacterial blood stream infections in critically ill septic patients outside the intensive care unit
Year2017
PMID28161884
Fungal Diseases involvedInvasive candidiasis
Associated Medical ConditionCritically ill septic patients
GenusCandida
Speciesspp.
OrganismCandida spp.
Ethical StatementThe study protocol was submitted and approved by our Local Ethics Committee (SepsiMed Study protocol number 0018329), and the study was performed in agreement with the principles set in the Declaration of Helsinki.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceBlood
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NamePCT
Biomarker Full NameProcalcitonin
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationItaly
CohortThis is a retrospective case–control study carried out in three internal medicine units (a total of 97 beds) of the University and General Hospital of Careggi, Florence, Italy, enrolling all cases of sepsis due to candidemia identified from January 1st 2012 to May 31st 2016.
Cohort No.64 Patients and 128 control
Age Group71.0 ± 14.8
P Valuep<0.0001
Sensitivity0.783
Specificity0.72
Positive Predictive Value0.151
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAssay
Analysis MethodVidas PCT Assay
ELISA kitsVidas PCT kit (Brahms D-agnostics, Berlin, Germany)
Assay DataNone
Validation Techniques usedVidas PCT Assay
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone