MycoBiomDB – Record Details (MyCo_7082)

Biomarker Record Details

Database ID: MyCo_7082
DB IDMyCo_7082
TitleA Polyclonal Antibody to NKX3.1 Identifies Fungal Organisms From the Esophagus
Year2019
PMID28777145
Fungal Diseases involvedEsophageal candidiasis
Associated Medical ConditionNone
GenusCandida
Speciesalbicans
OrganismCandida albicans
Ethical StatementThe study was approved by the University of Pittsburgh Institutional Review Board (IRB #PRO12050551).
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBiopsy
Sample sourceEsophageal biopsies
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameNKX3.1
Biomarker Full NameNKX3.1
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationPittsburgh, PA
CohortHere identified cases of esophageal biopsies on the basis of the search term “candida” from March 28, 2012 to December 27, 2013 at our institution. Of 85 cases for which 3 stains were available and at least 1 stain was positive for fungus con-sistent with Candida, 83 cases stained as positive with NKX3.1, compared with 79 with PASD and 75 with Grocott.
Cohort No.85
Age GroupNone
P Valuep< 0.05
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAnalytic
Analysis MethodultraView Universal DAB Detection analysis
ELISA kitsNone
Assay DataNone
Validation Techniques usedultraView Universal DAB Detection analysis
Up Regulation Down RegulationIncrease
Sequence DataNone
External LinkNone