| DB ID | MyCo_6792 |
| Title | Th2-skewed peripheral T-helper cells drive B-cells in allergic bronchopulmonary aspergillosis |
| Year | 2024 |
| PMID | 38514095 |
| Fungal Diseases involved | Allergic bronchopulmonary aspergillosis |
| Associated Medical Condition | None |
| Genus | Aspergillus |
| Species | fumigatus |
| Organism | Aspergillus fumigatus |
| Ethical Statement | The study protocol was approved by the institutional review board of Shanghai Pulmonary Hospital ( protocol number k18-153) and Tongji University School of Medicine (number 2015YXY95). All participants signed written informed consent. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | Th2-skewed Tph cells |
| Biomarker Full Name | Th2-skewed Tph cells |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | China |
| Cohort | 77 ABPA patients, 23 asthma patients and 32 healthy controls were enrolled. |
| Cohort No. | 77 Patients and 55 control |
| Age Group | 28-63.8 |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Allergic bronchopulmonary aspergillosis (ABPA), an allergic pulmonary disease with Aspergillus fumigatus sensitisation, is usually diagnosed in patients with asthma and/or cystic fibrosis. The estimated global burden of ABPA is 5 million. |
| Technique | Bioinformatics analysis |
| Analysis Method | Transcriptomics Analysis |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Flow Cytometry Analysis, Transcriptomics Analysis |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
