| DB ID | MyCo_6735 |
| Title | The host transcriptional response to Candidemia is dominated by neutrophil activation and heme biosynthesis and supports novel diagnostic approaches |
| Year | 2021 |
| PMID | 34225776 |
| Fungal Diseases involved | Candidemia |
| Associated Medical Condition | None |
| Genus | Candida |
| Species | spp. |
| Organism | Candida spp. |
| Ethical Statement | The study was approved by the IRB at Duke University Medical Center (Pro00083484) for all patient cohorts and was performed in accordance with the Declaration of Helsinki. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Blood |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | NEO1 |
| Biomarker Full Name | NEO1 |
| Biomarker Type | Diagnostic |
| Biomolecule | Gene |
| Geographical Location | USA |
| Cohort | The discovery cohort consisted of 138 subjects—23 with bloodstream infection with Candida spp. in the absence of other types of infection, 35 with bacterial infection, 48 with a viral infection, 17 with SIRS, and 15 with healthy controls. |
| Cohort No. | 23 Patients and 15 control |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Bioinformatics analysis |
| Analysis Method | Transcriptional analysis |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Transcriptional analysis |
| Up Regulation Down Regulation | Diffrenetially expressed |
| Sequence Data | None |
| External Link | None |
