| DB ID | MyCo_6491 |
| Title | The host response of CD28-deficient mice to Pneumocystis infection |
| Year | 2005 |
| PMID | 16324820 |
| Fungal Diseases involved | Pneumocystis |
| Associated Medical Condition | None |
| Genus | Pneumocystis |
| Species | carinii |
| Organism | Pneumocystis carinii |
| Ethical Statement | All animal experimentation was approved by the Washington University Animal Studies Committee. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Biopsy |
| Sample source | Extracted Lungs tissue |
| Host Group | Animal |
| Host Common name | Mice |
| Host Scientific name | Mus musculus |
| Biomarker Name | IL-10 |
| Biomarker Full Name | Interleukin-10 |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | USA |
| Cohort | C57BL/6J and B6.CB17-Prkdcscid/SzJ mice (B6.SCID) were purchased from Jackson Laboratories (Bar Harbor, ME). CD28-deficient mice have been previously described and IL-10 deficient mice in the C57BL/6 background were purchased from Jackson Laboratories (Bar Harbor, ME). |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Liquid chromatography |
| Analysis Method | Ribonuclease protection assay |
| ELISA kits | Riboquant multiprobe kit with the mCK-1 probe set (BD PharMingen Corporation, San Diego, CA) |
| Assay Data | None |
| Validation Techniques used | Ribonuclease protection assay |
| Up Regulation Down Regulation | Increase |
| Sequence Data | None |
| External Link | None |
