MycoBiomDB – Record Details (MyCo_6479)

Biomarker Record Details

Database ID: MyCo_6479
DB IDMyCo_6479
TitleReal-world efficacy of anti-IL-5 treatment in patients with allergic bronchopulmonary aspergillosis
Year2023
PMID37015988
Fungal Diseases involvedAllergic bronchopulmonary aspergillosis
Associated Medical ConditionNone
GenusAspergillus
Speciesspp.
OrganismAspergillus spp.
Ethical StatementThis study was approved by the Institutional Review Board for clinical research of the Tokai University Hospital (#18R-290 and #22R-161) and carried out according to the principles embodied in the Declaration of Helsinki of 1965, as revised in Brazil in 2013.
Site of InfectionNone
Opportunistic invasiveNone
Sample typeBody fluid
Sample sourceBronchoalveolar lavage fluid (BALF)
Host GroupHuman
Host Common nameHuman
Host Scientific nameHomo sapiens
Biomarker NameAnti-IL-5/IL-5Rα
Biomarker Full NameAnti-Interleukin-5/Interleukin-5 receptor α chain (Rα)
Biomarker TypeDiagnostic
BiomoleculeProtein
Geographical LocationJapan
CohortTwenty-nine patients with ABPM treated with anti-IL-5/IL-5Rα mAbs, including 22 (76%) women with a median age of 63 years, were registered from 15 clinical centers in Japan.
Cohort No.29
Age Group63
P ValueNone
SensitivityNone
SpecificityNone
Positive Predictive ValueNone
MICNone
Fold ChangeNone
PathwayNone
Disease Introduction MechanismNone
TechniqueAnalytic
Analysis MethodRadiographic assessment
ELISA kitsNone
Assay DataNone
Validation Techniques usedRadiographic assessment
Up Regulation Down RegulationPositive
Sequence DataNone
External LinkNone