| DB ID | MyCo_6469 |
| Title | Identification of Biomarkers for Resistance to Fusarium oxysporum f. sp. cubense Infection and in Silico Studies in Musa paradisiaca Cultivar Puttabale through Proteomic Approach |
| Year | 2016 |
| PMID | 28248219 |
| Fungal Diseases involved | Panama wilt |
| Associated Medical Condition | None |
| Genus | Fusarium |
| Species | oxysporum |
| Organism | Fusarium oxysporum f. spp. cubense (Foc) |
| Ethical Statement | None |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Plant extracts |
| Sample source | Plant extracts |
| Host Group | Plant |
| Host Common name | Banana |
| Host Scientific name | Musa paradisiaca |
| Biomarker Name | PMSRc |
| Biomarker Full Name | Peptide methionine sulfoxide reductase chloroplastic-like protein |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | India |
| Cohort | None |
| Cohort No. | None |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | Musa paradisiaca (L) cv. puttabale is an indigenous banana cultivar belongs to the AB genome cultivated in the Malnad region of Karnataka, India. The fruits are valued for their delicious taste but are highly prone to Fusarium oxysporum f. sp. cubense (Foc) infection. Universally, farmers apply high dose of commercial fungicides and pesticides for the obliteration of this pathogen. However, the pathogen Foc has mutated, becoming increasingly resistant to fungicides and adopted to various environmental stresses thus posing an imminent threat for global banana production. Conventional plants breeding techniques has been focused on disease resistant plants but are limited to several constraints such as polyploidy, heterozygosity, sterility, low fertility and limited genetic variability. Alternatively, mutation induction, somaclonal variation and in vitro selection technologies have a prominent role in improving disease resistant traits. Many investigators report the use of chemical mutagens such as ethyl-methane-sulfonate, diethyl sulfate, sodium azide and the Fusarium culture filtrate or Fusaric acid to improve Fusarium wilt resistant varieties of banana. |
| Technique | PCR |
| Analysis Method | qRT-PCR |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Proteomics Analysis, qRT-PCR |
| Up Regulation Down Regulation | Positive |
| Sequence Data | None |
| External Link | None |
