| DB ID | MyCo_6332 |
| Title | Serological proteomic biomarkers to identify Paracoccidioides species and risk of relapse |
| Year | 2018 |
| PMID | 30157221 |
| Fungal Diseases involved | Paracoccidioidomycosis |
| Associated Medical Condition | None |
| Genus | Paracoccidioides |
| Species | lutzii |
| Organism | Paracoccidioides lutzii |
| Ethical Statement | The study was approved by the Research Ethics Committee of the Faculdade de Medicina de Botucatu (UNESP), number 2.100.907, submission no. CAAE 21822813.9.0000.5411. |
| Site of Infection | None |
| Opportunistic invasive | None |
| Sample type | Body fluid |
| Sample source | Serum |
| Host Group | Human |
| Host Common name | Human |
| Host Scientific name | Homo sapiens |
| Biomarker Name | Alpha-1-antichymotrypsin |
| Biomarker Full Name | Alpha-1-antichymotrypsin |
| Biomarker Type | Diagnostic |
| Biomolecule | Protein |
| Geographical Location | Brazil |
| Cohort | A prospective paracoccidioidomycosis control surveillance has been performed since 1988 at the Clinical Mycology Outpatient Service of the Tropical Diseases Area of the Faculdade de Medicina de Botucatu–São Paulo State University (UNESP) and since 1980 at the Infectious and Parasitic Diseases Service of the Faculdade de Medicina—Federal University of Mato Grosso do Sul (UFMS). Proteomic analysis was performed in serum from 9 patients with PCM caused by P. brasiliensis, with and with- out relapse, from 4 patients with PCM produced by P. lutzii, and from 3 healthy controls. |
| Cohort No. | 13 patients and 3 control |
| Age Group | None |
| P Value | None |
| Sensitivity | None |
| Specificity | None |
| Positive Predictive Value | None |
| MIC | None |
| Fold Change | None |
| Pathway | None |
| Disease Introduction Mechanism | None |
| Technique | Bioinformatics analysis |
| Analysis Method | Proteomics Approach |
| ELISA kits | None |
| Assay Data | None |
| Validation Techniques used | Proteomics Approach |
| Up Regulation Down Regulation | Positive |
| Sequence Data | Access code: P01011.2 |
| External Link | None |
